ganirelix 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
gonadotropin-releasing-hormone (GnRH) inhibitors, peptides 1279 124904-93-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ganirelix
  • orgalutran
  • ganirelix acetate
Ganirelix is a GnRH antagonist, which modulates the hypothalamic-pituitary-gonadal axis by competitive binding to the GnRH receptors in the pituitary gland. As result a rapid, profound,reversible suppression of endogenous gonadotropins occurs, without initial stimulation as induced by GnRH agonists.
  • Molecular weight: 1570.35
  • Formula: C80H113ClN18O13
  • CLOGP: 1.55
  • LIPINSKI: 4
  • HAC: 31
  • HDO: 16
  • TPSA: 451.49
  • ALOGS: -5.47
  • ROTB: 44

Drug dosage:

DoseUnitRoute
0.25 mg P

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

ganirelix