Molfile
Inchi
Smiles
Synonyms:
-
ganirelix
-
orgalutran
-
ganirelix acetate
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Ganirelix is a GnRH antagonist, which modulates the hypothalamic-pituitary-gonadal axis by competitive binding to the GnRH receptors in the pituitary gland. As result a rapid, profound,reversible suppression of endogenous gonadotropins occurs, without initial stimulation as induced by GnRH agonists.
- Molecular weight: 1570.35
- Formula: C80H113ClN18O13
- CLOGP: 1.55
- LIPINSKI: 4
- HAC: 31
- HDO: 16
- TPSA: 451.49
- ALOGS: -5.47
- ROTB: 44
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