galactose Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1271 59-23-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • galactose
  • galactopyranose
  • alpha-D-Galactopyranose
  • microparticles of galactose
An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.
  • Molecular weight: 180.16
  • Formula: C6H12O6
  • CLOGP: -2.21
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 5
  • TPSA: 110.38
  • ALOGS: 0.64
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC V04CE01 VARIOUS
DIAGNOSTIC AGENTS
OTHER DIAGNOSTIC AGENTS
Tests for liver functional capacity
ATC V08DA02 VARIOUS
CONTRAST MEDIA
ULTRASOUND CONTRAST MEDIA
Ultrasound contrast media
CHEBI has role CHEBI:75771 Mus musculus metabolite
CHEBI has role CHEBI:78675 essential metabolite

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.87 acidic
pKa2 13.08 acidic
pKa3 13.91 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Jacalin Unclassified Kd 4.80 CHEMBL

External reference:

IDSource
4018618 VUID
N0000146931 NUI
D04291 KEGG_DRUG
4018618 VANDF
C0016945 UMLSCUI
CHEBI:28260 CHEBI
GLA PDB_CHEM_ID
CHEMBL300520 ChEMBL_ID
CHEMBL195923 ChEMBL_ID
CHEMBL1233058 ChEMBL_ID
DB11735 DRUGBANK_ID
D005690 MESH_DESCRIPTOR_UI
6036 PUBCHEM_CID
X2RN3Q8DNE UNII
4626 RXNORM
006112 NDDF
38182007 SNOMEDCT_US
423410006 SNOMEDCT_US

Pharmaceutical products:

None