Stem definition | Drug id | CAS RN |
---|---|---|
gabamimetic agents | 1264 | 60142-96-3 |
Dose | Unit | Route |
---|---|---|
1.80 | g | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 10 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 100 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 116.79 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 60 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.71 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 1.70 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.97 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 5.30 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 30, 1993 | FDA | PFIZER PHARMS |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 1707.99 | 9.78 | 4328 | 289448 | 239497 | 46152789 |
Drug ineffective for unapproved indication | 1111.83 | 9.78 | 881 | 292895 | 15532 | 46376754 |
Completed suicide | 526.61 | 9.78 | 2062 | 291714 | 143858 | 46248428 |
Multiple sclerosis relapse | 375.02 | 9.78 | 823 | 292953 | 41302 | 46350984 |
Pemphigus | 252.08 | 9.78 | 7 | 293769 | 45267 | 46347019 |
Rheumatoid arthritis | 239.76 | 9.78 | 746 | 293030 | 239469 | 46152817 |
Somnolence | 225.34 | 9.78 | 1721 | 292055 | 154800 | 46237486 |
Myoclonus | 220.01 | 9.78 | 354 | 293422 | 13998 | 46378288 |
Toxicity to various agents | 217.51 | 9.78 | 2161 | 291615 | 209605 | 46182681 |
Contraindicated product administered | 202.87 | 9.78 | 126 | 293650 | 79821 | 46312465 |
Maternal exposure during pregnancy | 198.75 | 9.78 | 211 | 293565 | 102338 | 46289948 |
Neuropathy peripheral | 180.82 | 9.78 | 1083 | 292693 | 89810 | 46302476 |
Neuralgia | 172.66 | 9.78 | 402 | 293374 | 20981 | 46371305 |
Fall | 169.96 | 9.78 | 2961 | 290815 | 326136 | 46066150 |
Synovitis | 168.23 | 9.78 | 87 | 293689 | 60988 | 46331298 |
Drug abuse | 160.70 | 9.78 | 807 | 292969 | 62601 | 46329685 |
Febrile neutropenia | 160.66 | 9.78 | 216 | 293560 | 94411 | 46297875 |
Balance disorder | 150.91 | 9.78 | 803 | 292973 | 63718 | 46328568 |
Memory impairment | 148.41 | 9.78 | 913 | 292863 | 76424 | 46315862 |
Accidental death | 147.26 | 9.78 | 109 | 293667 | 1726 | 46390560 |
Exposure during pregnancy | 146.24 | 9.78 | 287 | 293489 | 107925 | 46284361 |
Suicidal ideation | 144.58 | 9.78 | 720 | 293056 | 55662 | 46336624 |
Systemic lupus erythematosus | 140.37 | 9.78 | 122 | 293654 | 65058 | 46327228 |
Multiple sclerosis | 138.45 | 9.78 | 406 | 293370 | 24385 | 46367901 |
Depression | 137.62 | 9.78 | 1656 | 292120 | 168448 | 46223838 |
Feeling abnormal | 125.18 | 9.78 | 1270 | 292506 | 123790 | 46268496 |
Tremor | 121.87 | 9.78 | 1187 | 292589 | 114452 | 46277834 |
Hypoaesthesia | 117.47 | 9.78 | 1204 | 292572 | 117665 | 46274621 |
General physical health deterioration | 115.67 | 9.78 | 359 | 293417 | 115410 | 46276876 |
Hand deformity | 113.31 | 9.78 | 38 | 293738 | 34536 | 46357750 |
Product complaint | 112.86 | 9.78 | 241 | 293535 | 11860 | 46380426 |
Rheumatoid factor positive | 107.54 | 9.78 | 5 | 293771 | 20456 | 46371830 |
Dizziness | 107.02 | 9.78 | 2851 | 290925 | 337563 | 46054723 |
Pyrexia | 104.64 | 9.78 | 1555 | 292221 | 347247 | 46045039 |
Glossodynia | 100.55 | 9.78 | 79 | 293697 | 44294 | 46347992 |
Device expulsion | 98.03 | 9.78 | 26 | 293750 | 27516 | 46364770 |
Anaemia | 96.72 | 9.78 | 1086 | 292690 | 254693 | 46137593 |
Pericarditis | 92.26 | 9.78 | 19 | 293757 | 23908 | 46368378 |
Muscle spasms | 91.10 | 9.78 | 1179 | 292597 | 121934 | 46270352 |
Confusional state | 90.45 | 9.78 | 1461 | 292315 | 158431 | 46233855 |
C-reactive protein abnormal | 88.26 | 9.78 | 14 | 293762 | 21256 | 46371030 |
Interstitial lung disease | 86.71 | 9.78 | 128 | 293648 | 53821 | 46338465 |
Drug withdrawal syndrome | 85.89 | 9.78 | 371 | 293405 | 27013 | 46365273 |
Gait disturbance | 85.04 | 9.78 | 1335 | 292441 | 143928 | 46248358 |
Hallucination | 84.91 | 9.78 | 572 | 293204 | 49379 | 46342907 |
Vision blurred | 84.82 | 9.78 | 820 | 292956 | 78888 | 46313398 |
Thrombocytopenia | 84.71 | 9.78 | 459 | 293317 | 126122 | 46266164 |
Infusion related reaction | 83.63 | 9.78 | 340 | 293436 | 100868 | 46291418 |
C-reactive protein increased | 82.97 | 9.78 | 151 | 293625 | 58439 | 46333847 |
Withdrawal syndrome | 82.81 | 9.78 | 277 | 293499 | 17857 | 46374429 |
Mental status changes | 82.28 | 9.78 | 464 | 293312 | 37624 | 46354662 |
Respiratory arrest | 81.88 | 9.78 | 425 | 293351 | 33391 | 46358895 |
Product dose omission issue | 79.56 | 9.78 | 1496 | 292280 | 167024 | 46225262 |
Sedation | 79.38 | 9.78 | 320 | 293456 | 22590 | 46369696 |
Joint swelling | 77.89 | 9.78 | 669 | 293107 | 165404 | 46226882 |
Pain in extremity | 76.77 | 9.78 | 2151 | 291625 | 256529 | 46135757 |
Hepatic function abnormal | 72.20 | 9.78 | 66 | 293710 | 34355 | 46357931 |
Treatment failure | 69.42 | 9.78 | 325 | 293451 | 92762 | 46299524 |
Cytomegalovirus infection | 68.74 | 9.78 | 15 | 293761 | 18129 | 46374157 |
Cardiac failure | 68.31 | 9.78 | 265 | 293511 | 79683 | 46312603 |
Paraesthesia | 65.22 | 9.78 | 1070 | 292706 | 116367 | 46275919 |
Migraine | 64.75 | 9.78 | 700 | 293076 | 69326 | 46322960 |
Multiple organ dysfunction syndrome | 64.06 | 9.78 | 144 | 293632 | 51566 | 46340720 |
Pancytopenia | 64.00 | 9.78 | 296 | 293480 | 84762 | 46307524 |
Trigeminal neuralgia | 62.03 | 9.78 | 85 | 293691 | 2904 | 46389382 |
Neutropenia | 61.41 | 9.78 | 590 | 293186 | 142614 | 46249672 |
Amnesia | 58.78 | 9.78 | 456 | 293320 | 41175 | 46351111 |
Sopor | 58.67 | 9.78 | 264 | 293512 | 19564 | 46372722 |
Coordination abnormal | 57.98 | 9.78 | 176 | 293600 | 10773 | 46381513 |
Seizure | 57.55 | 9.78 | 1091 | 292685 | 121963 | 46270323 |
Premature baby | 57.47 | 9.78 | 21 | 293755 | 18091 | 46374195 |
Anxiety | 57.30 | 9.78 | 1525 | 292251 | 180432 | 46211854 |
Foetal exposure during pregnancy | 56.52 | 9.78 | 66 | 293710 | 30681 | 46361605 |
Pleural effusion | 56.47 | 9.78 | 299 | 293477 | 82653 | 46309633 |
Unresponsive to stimuli | 56.21 | 9.78 | 371 | 293405 | 31803 | 46360483 |
Drug dependence | 55.93 | 9.78 | 261 | 293515 | 19640 | 46372646 |
Product use in unapproved indication | 55.22 | 9.78 | 836 | 292940 | 89437 | 46302849 |
Dyskinesia | 55.14 | 9.78 | 341 | 293435 | 28584 | 46363702 |
Red blood cell sedimentation rate abnormal | 54.39 | 9.78 | 10 | 293766 | 13639 | 46378647 |
Atrial fibrillation | 54.20 | 9.78 | 405 | 293371 | 103185 | 46289101 |
Burning sensation | 53.86 | 9.78 | 470 | 293306 | 43941 | 46348345 |
Mucosal inflammation | 53.81 | 9.78 | 102 | 293674 | 38874 | 46353412 |
Hypokalaemia | 52.56 | 9.78 | 331 | 293445 | 87693 | 46304593 |
Leukopenia | 52.50 | 9.78 | 236 | 293540 | 68107 | 46324179 |
Fibromyalgia | 52.37 | 9.78 | 401 | 293375 | 36062 | 46356224 |
Hepatic enzyme increased | 52.28 | 9.78 | 301 | 293475 | 81486 | 46310800 |
Muscular weakness | 51.41 | 9.78 | 838 | 292938 | 91006 | 46301280 |
Malignant neoplasm progression | 51.20 | 9.78 | 222 | 293554 | 64704 | 46327582 |
Bone marrow failure | 51.06 | 9.78 | 67 | 293709 | 29602 | 46362684 |
Insomnia | 49.85 | 9.78 | 1375 | 292401 | 163549 | 46228737 |
Hypersomnia | 49.82 | 9.78 | 211 | 293565 | 15228 | 46377058 |
Lethargy | 48.92 | 9.78 | 515 | 293261 | 50656 | 46341630 |
Hyponatraemia | 48.46 | 9.78 | 406 | 293370 | 100926 | 46291360 |
Blood lactate dehydrogenase increased | 48.36 | 9.78 | 35 | 293741 | 20465 | 46371821 |
Erythema | 48.30 | 9.78 | 621 | 293155 | 142199 | 46250087 |
Mental disorder | 46.99 | 9.78 | 271 | 293505 | 22154 | 46370132 |
Drug reaction with eosinophilia and systemic symptoms | 46.60 | 9.78 | 71 | 293705 | 29477 | 46362809 |
Therapeutic response decreased | 46.54 | 9.78 | 129 | 293647 | 43016 | 46349270 |
Feeling drunk | 45.35 | 9.78 | 85 | 293691 | 3802 | 46388484 |
Arthropathy | 45.33 | 9.78 | 329 | 293447 | 84371 | 46307915 |
Abortion spontaneous | 44.52 | 9.78 | 134 | 293642 | 43512 | 46348774 |
Speech disorder | 44.51 | 9.78 | 384 | 293392 | 35783 | 46356503 |
Sleep apnoea syndrome | 44.39 | 9.78 | 265 | 293511 | 21936 | 46370350 |
Respiratory depression | 43.40 | 9.78 | 166 | 293610 | 11434 | 46380852 |
Osteonecrosis of jaw | 43.26 | 9.78 | 95 | 293681 | 34307 | 46357979 |
Drug resistance | 43.17 | 9.78 | 28 | 293748 | 17340 | 46374946 |
Septic shock | 42.63 | 9.78 | 203 | 293573 | 57690 | 46334596 |
Pleural thickening | 42.52 | 9.78 | 66 | 293710 | 2529 | 46389757 |
Presbyacusis | 42.42 | 9.78 | 69 | 293707 | 2753 | 46389533 |
Live birth | 42.41 | 9.78 | 7 | 293769 | 10323 | 46381963 |
Myocardial stunning | 42.01 | 9.78 | 21 | 293755 | 154 | 46392132 |
Muscle twitching | 41.66 | 9.78 | 193 | 293583 | 14479 | 46377807 |
Hepatotoxicity | 41.50 | 9.78 | 58 | 293718 | 24951 | 46367335 |
Inadequate analgesia | 41.03 | 9.78 | 68 | 293708 | 2756 | 46389530 |
Premature delivery | 40.97 | 9.78 | 47 | 293729 | 22022 | 46370264 |
Cardio-respiratory arrest | 40.78 | 9.78 | 565 | 293211 | 59304 | 46332982 |
Restless legs syndrome | 40.36 | 9.78 | 202 | 293574 | 15641 | 46376645 |
Pleural fibrosis | 40.34 | 9.78 | 77 | 293699 | 3492 | 46388794 |
Intentional product misuse | 40.31 | 9.78 | 464 | 293312 | 46664 | 46345622 |
Crying | 40.14 | 9.78 | 249 | 293527 | 20892 | 46371394 |
Anaphylactic shock | 40.05 | 9.78 | 41 | 293735 | 20233 | 46372053 |
Duodenal ulcer perforation | 39.13 | 9.78 | 4 | 293772 | 8498 | 46383788 |
Cognitive disorder | 38.50 | 9.78 | 378 | 293398 | 36505 | 46355781 |
Full blood count decreased | 38.12 | 9.78 | 255 | 293521 | 21956 | 46370330 |
Therapeutic response unexpected | 37.61 | 9.78 | 196 | 293580 | 15420 | 46376866 |
Blood magnesium increased | 37.59 | 9.78 | 68 | 293708 | 2959 | 46389327 |
Euphoric mood | 37.46 | 9.78 | 83 | 293693 | 4189 | 46388097 |
Pneumocystis jirovecii pneumonia | 37.33 | 9.78 | 25 | 293751 | 15223 | 46377063 |
Head injury | 36.54 | 9.78 | 273 | 293503 | 24363 | 46367923 |
Bradycardia | 36.21 | 9.78 | 256 | 293520 | 66042 | 46326244 |
Premature labour | 36.02 | 9.78 | 13 | 293763 | 11286 | 46381000 |
Hepatocellular injury | 35.92 | 9.78 | 83 | 293693 | 29439 | 46362847 |
Impaired driving ability | 35.84 | 9.78 | 81 | 293695 | 4143 | 46388143 |
Abdominal discomfort | 34.54 | 9.78 | 707 | 293069 | 150458 | 46241828 |
Peritonitis | 34.41 | 9.78 | 48 | 293728 | 20666 | 46371620 |
Influenza like illness | 34.36 | 9.78 | 531 | 293245 | 57039 | 46335247 |
Ascites | 34.04 | 9.78 | 117 | 293659 | 36467 | 46355819 |
Eosinophilic colitis | 34.00 | 9.78 | 16 | 293760 | 101 | 46392185 |
Melaena | 33.85 | 9.78 | 78 | 293698 | 27694 | 46364592 |
Alopecia | 33.54 | 9.78 | 772 | 293004 | 161642 | 46230644 |
Bone erosion | 33.44 | 9.78 | 9 | 293767 | 9434 | 46382852 |
Diplopia | 33.43 | 9.78 | 223 | 293553 | 19182 | 46373104 |
Dry mouth | 33.31 | 9.78 | 508 | 293268 | 54418 | 46337868 |
Hepatic failure | 33.08 | 9.78 | 104 | 293672 | 33312 | 46358974 |
Off label use | 32.93 | 9.78 | 2006 | 291770 | 377835 | 46014451 |
Pain | 32.91 | 9.78 | 3454 | 290322 | 473494 | 45918792 |
Hypermobility syndrome | 32.74 | 9.78 | 30 | 293746 | 649 | 46391637 |
Rash maculo-papular | 32.61 | 9.78 | 80 | 293696 | 27794 | 46364492 |
Stiff person syndrome | 32.46 | 9.78 | 18 | 293758 | 167 | 46392119 |
Cough | 32.20 | 9.78 | 1155 | 292621 | 229094 | 46163192 |
Febrile bone marrow aplasia | 32.18 | 9.78 | 3 | 293773 | 6859 | 46385427 |
Hyperaesthesia | 31.53 | 9.78 | 115 | 293661 | 7741 | 46384545 |
Jaundice | 31.29 | 9.78 | 86 | 293690 | 28759 | 46363527 |
Ataxia | 30.94 | 9.78 | 171 | 293605 | 13759 | 46378527 |
Neck pain | 30.70 | 9.78 | 504 | 293272 | 54802 | 46337484 |
Epigastric discomfort | 30.69 | 9.78 | 92 | 293684 | 5592 | 46386694 |
Mood altered | 30.46 | 9.78 | 162 | 293614 | 12845 | 46379441 |
Helicobacter infection | 30.45 | 9.78 | 18 | 293758 | 11718 | 46380568 |
Diabetic neuropathy | 30.32 | 9.78 | 71 | 293705 | 3718 | 46388568 |
Pregnancy | 30.12 | 9.78 | 80 | 293696 | 27057 | 46365229 |
Hallucination, visual | 29.96 | 9.78 | 204 | 293572 | 17669 | 46374617 |
Accidental poisoning | 29.70 | 9.78 | 27 | 293749 | 578 | 46391708 |
Nerve injury | 29.43 | 9.78 | 111 | 293665 | 7594 | 46384692 |
Deafness neurosensory | 29.42 | 9.78 | 78 | 293698 | 4416 | 46387870 |
Nervousness | 29.32 | 9.78 | 291 | 293485 | 28184 | 46364102 |
Thrombotic microangiopathy | 29.25 | 9.78 | 8 | 293768 | 8298 | 46383988 |
Epistaxis | 29.23 | 9.78 | 261 | 293515 | 64044 | 46328242 |
Urinary incontinence | 29.10 | 9.78 | 291 | 293485 | 28239 | 46364047 |
Somatic symptom disorder | 29.08 | 9.78 | 47 | 293729 | 1865 | 46390421 |
Rash | 28.61 | 9.78 | 1896 | 291880 | 354616 | 46037670 |
Gastrointestinal haemorrhage | 28.58 | 9.78 | 330 | 293446 | 77043 | 46315243 |
Intervertebral disc protrusion | 28.52 | 9.78 | 223 | 293553 | 20182 | 46372104 |
Back pain | 27.96 | 9.78 | 1602 | 292174 | 208437 | 46183849 |
Rheumatoid nodule | 27.71 | 9.78 | 11 | 293765 | 9009 | 46383277 |
Toxic epidermal necrolysis | 27.62 | 9.78 | 62 | 293714 | 22216 | 46370070 |
Spinal operation | 27.43 | 9.78 | 87 | 293689 | 5453 | 46386833 |
Congenital thrombocytopenia | 27.40 | 9.78 | 11 | 293765 | 44 | 46392242 |
Anger | 27.34 | 9.78 | 147 | 293629 | 11705 | 46380581 |
Gestational diabetes | 27.28 | 9.78 | 6 | 293770 | 7213 | 46385073 |
Back disorder | 27.26 | 9.78 | 122 | 293654 | 9019 | 46383267 |
Gait inability | 26.79 | 9.78 | 339 | 293437 | 34864 | 46357422 |
Fatigue | 26.57 | 9.78 | 4287 | 289489 | 604410 | 45787876 |
Cyst | 26.52 | 9.78 | 148 | 293628 | 11952 | 46380334 |
Myelodysplastic syndrome | 26.50 | 9.78 | 36 | 293740 | 15675 | 46376611 |
Agranulocytosis | 26.49 | 9.78 | 63 | 293713 | 22122 | 46370164 |
Acute respiratory distress syndrome | 26.37 | 9.78 | 62 | 293714 | 21860 | 46370426 |
Limb discomfort | 26.05 | 9.78 | 238 | 293538 | 22538 | 46369748 |
Concussion | 26.02 | 9.78 | 100 | 293676 | 6903 | 46385383 |
Somatic delusion | 25.58 | 9.78 | 25 | 293751 | 588 | 46391698 |
Hypersensitivity | 25.56 | 9.78 | 735 | 293041 | 149586 | 46242700 |
Human epidermal growth factor receptor decreased | 25.34 | 9.78 | 8 | 293768 | 12 | 46392274 |
Incoherent | 25.28 | 9.78 | 74 | 293702 | 4438 | 46387848 |
Tachycardia | 25.17 | 9.78 | 458 | 293318 | 99164 | 46293122 |
Complex regional pain syndrome | 25.13 | 9.78 | 46 | 293730 | 2020 | 46390266 |
Drug-induced liver injury | 25.07 | 9.78 | 79 | 293697 | 25289 | 46366997 |
Lower respiratory tract infection | 24.86 | 9.78 | 224 | 293552 | 54865 | 46337421 |
Paranoia | 24.83 | 9.78 | 132 | 293644 | 10465 | 46381821 |
Cerebral infarction | 24.36 | 9.78 | 71 | 293705 | 23295 | 46368991 |
Haemophagocytic lymphohistiocytosis | 24.31 | 9.78 | 11 | 293765 | 8331 | 46383955 |
Asterixis | 24.04 | 9.78 | 34 | 293742 | 1197 | 46391089 |
Drug screen positive | 23.93 | 9.78 | 66 | 293710 | 3825 | 46388461 |
Liver injury | 23.77 | 9.78 | 40 | 293736 | 15961 | 46376325 |
Focal dyscognitive seizures | 23.74 | 9.78 | 54 | 293722 | 2774 | 46389512 |
Haemoglobin decreased | 23.60 | 9.78 | 624 | 293152 | 128325 | 46263961 |
Alanine aminotransferase increased | 23.50 | 9.78 | 403 | 293373 | 88048 | 46304238 |
Psychotic disorder due to a general medical condition | 23.36 | 9.78 | 15 | 293761 | 186 | 46392100 |
Intervertebral disc degeneration | 23.26 | 9.78 | 153 | 293623 | 13099 | 46379187 |
Transplant rejection | 23.14 | 9.78 | 16 | 293760 | 9580 | 46382706 |
Transaminases increased | 23.07 | 9.78 | 93 | 293683 | 27668 | 46364618 |
Ankle fracture | 23.06 | 9.78 | 172 | 293604 | 15339 | 46376947 |
Therapeutic product effect decreased | 23.04 | 9.78 | 373 | 293403 | 82228 | 46310058 |
Poisoning | 23.02 | 9.78 | 159 | 293617 | 13835 | 46378451 |
Cerebral haemorrhage | 22.98 | 9.78 | 96 | 293680 | 28275 | 46364011 |
Dyspnoea | 22.82 | 9.78 | 2869 | 290907 | 512679 | 45879607 |
Blood bilirubin increased | 22.82 | 9.78 | 124 | 293652 | 34060 | 46358226 |
Urinary tract infection | 22.75 | 9.78 | 1644 | 292132 | 218622 | 46173664 |
Central nervous system lesion | 22.69 | 9.78 | 120 | 293656 | 9495 | 46382791 |
Mental impairment | 22.59 | 9.78 | 145 | 293631 | 12311 | 46379975 |
Pre-eclampsia | 22.58 | 9.78 | 11 | 293765 | 7983 | 46384303 |
Visual impairment | 22.42 | 9.78 | 564 | 293212 | 66125 | 46326161 |
Dysarthria | 22.42 | 9.78 | 346 | 293430 | 37152 | 46355134 |
Anorgasmia | 22.40 | 9.78 | 23 | 293753 | 575 | 46391711 |
Sacroiliitis | 22.34 | 9.78 | 45 | 293731 | 2124 | 46390162 |
Drug titration error | 22.27 | 9.78 | 23 | 293753 | 579 | 46391707 |
Neutropenic sepsis | 22.07 | 9.78 | 27 | 293749 | 12297 | 46379989 |
Hyperreflexia | 22.02 | 9.78 | 78 | 293698 | 5176 | 46387110 |
Eosinophilia | 21.82 | 9.78 | 56 | 293720 | 19161 | 46373125 |
Limb injury | 21.74 | 9.78 | 200 | 293576 | 18974 | 46373312 |
Bone cyst | 21.66 | 9.78 | 43 | 293733 | 2008 | 46390278 |
Acute kidney injury | 21.57 | 9.78 | 1239 | 292537 | 234616 | 46157670 |
Nightmare | 21.35 | 9.78 | 178 | 293598 | 16420 | 46375866 |
Acute myeloid leukaemia | 21.16 | 9.78 | 42 | 293734 | 15736 | 46376550 |
Device difficult to use | 21.16 | 9.78 | 12 | 293764 | 7992 | 46384294 |
Overdose | 21.11 | 9.78 | 813 | 292963 | 101166 | 46291120 |
Lactic acidosis | 21.02 | 9.78 | 126 | 293650 | 33783 | 46358503 |
Haemorrhage | 20.66 | 9.78 | 233 | 293543 | 54636 | 46337650 |
Accidental exposure to product | 20.59 | 9.78 | 66 | 293710 | 21015 | 46371271 |
Dysstasia | 20.39 | 9.78 | 185 | 293591 | 17483 | 46374803 |
Disseminated intravascular coagulation | 20.36 | 9.78 | 57 | 293719 | 18948 | 46373338 |
Substance abuse | 20.23 | 9.78 | 65 | 293711 | 4102 | 46388184 |
Abdominal pain | 20.21 | 9.78 | 1213 | 292563 | 228818 | 46163468 |
Drug diversion | 20.20 | 9.78 | 26 | 293750 | 835 | 46391451 |
Vertigo | 20.19 | 9.78 | 449 | 293327 | 51599 | 46340687 |
Foetal growth restriction | 20.19 | 9.78 | 8 | 293768 | 6559 | 46385727 |
Thinking abnormal | 20.17 | 9.78 | 118 | 293658 | 9696 | 46382590 |
Red blood cell sedimentation rate increased | 20.10 | 9.78 | 75 | 293701 | 22814 | 46369472 |
Tuberculosis | 20.00 | 9.78 | 21 | 293755 | 10244 | 46382042 |
Abortion induced | 19.98 | 9.78 | 21 | 293755 | 10239 | 46382047 |
Cholestasis | 19.97 | 9.78 | 94 | 293682 | 26799 | 46365487 |
Device use error | 19.66 | 9.78 | 4 | 293772 | 5077 | 46387209 |
Pre-existing condition improved | 19.53 | 9.78 | 88 | 293688 | 6524 | 46385762 |
Haematoma | 19.45 | 9.78 | 119 | 293657 | 31753 | 46360533 |
Device dislocation | 19.43 | 9.78 | 71 | 293705 | 21731 | 46370555 |
Bronchiectasis | 19.37 | 9.78 | 18 | 293758 | 9298 | 46382988 |
Torsade de pointes | 19.36 | 9.78 | 29 | 293747 | 12125 | 46380161 |
Cardiogenic shock | 19.18 | 9.78 | 47 | 293729 | 16337 | 46375949 |
Therapy non-responder | 19.15 | 9.78 | 166 | 293610 | 40986 | 46351300 |
Caesarean section | 19.15 | 9.78 | 48 | 293728 | 16555 | 46375731 |
Gamma-glutamyltransferase increased | 19.12 | 9.78 | 119 | 293657 | 31621 | 46360665 |
Autonomic nervous system imbalance | 18.91 | 9.78 | 45 | 293731 | 2381 | 46389905 |
Unintentional medical device removal | 18.88 | 9.78 | 3 | 293773 | 4550 | 46387736 |
Posterior reversible encephalopathy syndrome | 18.88 | 9.78 | 42 | 293734 | 15099 | 46377187 |
Irritability | 18.83 | 9.78 | 271 | 293505 | 28675 | 46363611 |
Hepatitis | 18.78 | 9.78 | 122 | 293654 | 32093 | 46360193 |
Serotonin syndrome | 18.75 | 9.78 | 234 | 293542 | 23986 | 46368300 |
Ventricular fibrillation | 18.73 | 9.78 | 27 | 293749 | 11469 | 46380817 |
Dysphemia | 18.67 | 9.78 | 44 | 293732 | 2314 | 46389972 |
Joint injury | 18.67 | 9.78 | 194 | 293582 | 19015 | 46373271 |
Metastases to liver | 18.65 | 9.78 | 62 | 293714 | 19523 | 46372763 |
Pulmonary aplasia | 18.63 | 9.78 | 6 | 293770 | 10 | 46392276 |
Hypotension | 18.44 | 9.78 | 1238 | 292538 | 231351 | 46160935 |
Peroneal nerve palsy | 18.44 | 9.78 | 63 | 293713 | 4105 | 46388181 |
Allodynia | 18.40 | 9.78 | 20 | 293756 | 535 | 46391751 |
Colitis ulcerative | 18.40 | 9.78 | 54 | 293722 | 17678 | 46374608 |
Drug effective for unapproved indication | 18.34 | 9.78 | 34 | 293742 | 1508 | 46390778 |
Brain injury | 18.28 | 9.78 | 82 | 293694 | 6068 | 46386218 |
Post herpetic neuralgia | 18.23 | 9.78 | 39 | 293737 | 1921 | 46390365 |
Acute hepatic failure | 18.22 | 9.78 | 41 | 293735 | 14680 | 46377606 |
Wrong patient received product | 17.84 | 9.78 | 36 | 293740 | 1701 | 46390585 |
Neutrophil count decreased | 17.72 | 9.78 | 181 | 293595 | 43245 | 46349041 |
Vomiting | 17.59 | 9.78 | 2540 | 291236 | 450254 | 45942032 |
Shock haemorrhagic | 17.54 | 9.78 | 17 | 293759 | 8607 | 46383679 |
Pituitary tumour benign | 17.46 | 9.78 | 35 | 293741 | 1646 | 46390640 |
Hyperhidrosis | 17.32 | 9.78 | 707 | 293069 | 88601 | 46303685 |
Face oedema | 17.32 | 9.78 | 62 | 293714 | 19091 | 46373195 |
Myoclonic epilepsy | 17.30 | 9.78 | 25 | 293751 | 898 | 46391388 |
Body height decreased | 17.28 | 9.78 | 112 | 293664 | 9540 | 46382746 |
Graft versus host disease | 17.24 | 9.78 | 10 | 293766 | 6578 | 46385708 |
Secondary progressive multiple sclerosis | 17.22 | 9.78 | 29 | 293747 | 1191 | 46391095 |
Progressive multiple sclerosis | 17.16 | 9.78 | 23 | 293753 | 769 | 46391517 |
Genital haemorrhage | 17.13 | 9.78 | 10 | 293766 | 6556 | 46385730 |
Nerve compression | 17.09 | 9.78 | 87 | 293689 | 6781 | 46385505 |
Myelosuppression | 17.09 | 9.78 | 14 | 293762 | 7689 | 46384597 |
Circulatory collapse | 17.00 | 9.78 | 74 | 293702 | 21550 | 46370736 |
Muscle tightness | 16.90 | 9.78 | 117 | 293659 | 10188 | 46382098 |
Liver function test abnormal | 16.88 | 9.78 | 199 | 293577 | 46288 | 46345998 |
Discomfort | 16.86 | 9.78 | 200 | 293576 | 46470 | 46345816 |
Bone density decreased | 16.80 | 9.78 | 22 | 293754 | 9730 | 46382556 |
Colitis | 16.79 | 9.78 | 152 | 293624 | 37195 | 46355091 |
Prescription drug used without a prescription | 16.78 | 9.78 | 31 | 293745 | 1371 | 46390915 |
Stillbirth | 16.78 | 9.78 | 10 | 293766 | 6481 | 46385805 |
Surgery | 16.60 | 9.78 | 264 | 293512 | 28521 | 46363765 |
Toxic skin eruption | 16.59 | 9.78 | 33 | 293743 | 12354 | 46379932 |
Liver disorder | 16.56 | 9.78 | 152 | 293624 | 37094 | 46355192 |
Hyperbilirubinaemia | 16.54 | 9.78 | 25 | 293751 | 10413 | 46381873 |
Pharyngitis | 16.51 | 9.78 | 56 | 293720 | 17527 | 46374759 |
Femur fracture | 16.45 | 9.78 | 151 | 293625 | 36846 | 46355440 |
Drug use disorder | 16.44 | 9.78 | 46 | 293730 | 2689 | 46389597 |
Cytomegalovirus viraemia | 16.37 | 9.78 | 4 | 293772 | 4474 | 46387812 |
Tardive dyskinesia | 16.35 | 9.78 | 92 | 293684 | 7451 | 46384835 |
Asthma | 16.21 | 9.78 | 445 | 293331 | 91097 | 46301189 |
Injection site mass | 16.11 | 9.78 | 155 | 293621 | 14885 | 46377401 |
Atonic urinary bladder | 16.09 | 9.78 | 9 | 293767 | 85 | 46392201 |
Obstructive airways disorder | 16.08 | 9.78 | 38 | 293738 | 13374 | 46378912 |
Cardiac arrest | 16.03 | 9.78 | 709 | 293067 | 89690 | 46302596 |
Metabolic encephalopathy | 16.03 | 9.78 | 72 | 293704 | 5331 | 46386955 |
Panniculitis | 15.89 | 9.78 | 8 | 293768 | 5696 | 46386590 |
Bipolar disorder | 15.87 | 9.78 | 88 | 293688 | 7089 | 46385197 |
Angioedema | 15.63 | 9.78 | 165 | 293611 | 39177 | 46353109 |
Sensory loss | 15.51 | 9.78 | 85 | 293691 | 6817 | 46385469 |
Palmar-plantar erythrodysaesthesia syndrome | 15.47 | 9.78 | 71 | 293705 | 20380 | 46371906 |
Epstein-Barr virus infection | 15.46 | 9.78 | 12 | 293764 | 6772 | 46385514 |
Aspartate aminotransferase increased | 15.42 | 9.78 | 377 | 293399 | 78323 | 46313963 |
Hypokinesia | 15.42 | 9.78 | 123 | 293653 | 11199 | 46381087 |
Proteinuria | 15.36 | 9.78 | 53 | 293723 | 16500 | 46375786 |
Lupus-like syndrome | 15.34 | 9.78 | 16 | 293760 | 7828 | 46384458 |
Head banging | 15.33 | 9.78 | 16 | 293760 | 408 | 46391878 |
Suspected suicide | 15.27 | 9.78 | 64 | 293712 | 4597 | 46387689 |
Therapy cessation | 15.27 | 9.78 | 244 | 293532 | 26385 | 46365901 |
Pericardial effusion | 15.26 | 9.78 | 96 | 293680 | 25447 | 46366839 |
Economic problem | 15.25 | 9.78 | 37 | 293739 | 1983 | 46390303 |
Uterine perforation | 15.16 | 9.78 | 14 | 293762 | 7253 | 46385033 |
Exposure via ingestion | 14.98 | 9.78 | 52 | 293724 | 3415 | 46388871 |
Urticaria | 14.98 | 9.78 | 598 | 293178 | 117294 | 46274992 |
Ejection fraction decreased | 14.96 | 9.78 | 60 | 293716 | 17877 | 46374409 |
Rash erythematous | 14.92 | 9.78 | 141 | 293635 | 34209 | 46358077 |
Hostility | 14.92 | 9.78 | 29 | 293747 | 1333 | 46390953 |
Postmortem blood drug level abnormal | 14.87 | 9.78 | 14 | 293762 | 314 | 46391972 |
Exostosis | 14.81 | 9.78 | 113 | 293663 | 10150 | 46382136 |
Skin reaction | 14.80 | 9.78 | 29 | 293747 | 10917 | 46381369 |
Disturbance in attention | 14.79 | 9.78 | 280 | 293496 | 31280 | 46361006 |
Oligohydramnios | 14.72 | 9.78 | 8 | 293768 | 5457 | 46386829 |
Ventricular tachycardia | 14.63 | 9.78 | 56 | 293720 | 16911 | 46375375 |
Facial pain | 14.59 | 9.78 | 90 | 293686 | 7535 | 46384751 |
Low birth weight baby | 14.57 | 9.78 | 8 | 293768 | 5426 | 46386860 |
Pulmonary fibrosis | 14.47 | 9.78 | 71 | 293705 | 20021 | 46372265 |
Hypercholesterolaemia | 14.36 | 9.78 | 32 | 293744 | 11498 | 46380788 |
Acute myocardial infarction | 14.32 | 9.78 | 130 | 293646 | 31794 | 46360492 |
Tooth loss | 14.21 | 9.78 | 81 | 293695 | 6592 | 46385694 |
Jaundice cholestatic | 14.09 | 9.78 | 7 | 293769 | 5022 | 46387264 |
Myotonia | 14.08 | 9.78 | 10 | 293766 | 148 | 46392138 |
Disorganised speech | 14.06 | 9.78 | 22 | 293754 | 849 | 46391437 |
Deprescribing error | 14.05 | 9.78 | 6 | 293770 | 29 | 46392257 |
Agitation | 14.00 | 9.78 | 452 | 293324 | 54963 | 46337323 |
Blood lactic acid | 13.99 | 9.78 | 9 | 293767 | 112 | 46392174 |
Contusion | 13.97 | 9.78 | 679 | 293097 | 86808 | 46305478 |
Tubulointerstitial nephritis | 13.96 | 9.78 | 47 | 293729 | 14741 | 46377545 |
Carpal tunnel syndrome | 13.94 | 9.78 | 157 | 293619 | 15702 | 46376584 |
Tumour lysis syndrome | 13.88 | 9.78 | 15 | 293761 | 7221 | 46385065 |
Bronchopulmonary aspergillosis | 13.87 | 9.78 | 16 | 293760 | 7480 | 46384806 |
Acute coronary syndrome | 13.82 | 9.78 | 27 | 293749 | 10177 | 46382109 |
Mucocutaneous haemorrhage | 13.82 | 9.78 | 7 | 293769 | 53 | 46392233 |
Hepatitis cholestatic | 13.77 | 9.78 | 13 | 293763 | 6664 | 46385622 |
Osteosclerosis | 13.72 | 9.78 | 51 | 293725 | 3465 | 46388821 |
Metabolic acidosis | 13.70 | 9.78 | 167 | 293609 | 38613 | 46353673 |
Complication of device insertion | 13.67 | 9.78 | 7 | 293769 | 4937 | 46387349 |
Pulmonary embolism | 13.54 | 9.78 | 552 | 293224 | 108033 | 46284253 |
Congenital absence of vertebra | 13.54 | 9.78 | 5 | 293771 | 15 | 46392271 |
Coma | 13.48 | 9.78 | 471 | 293305 | 57878 | 46334408 |
Pancreatitis chronic | 13.46 | 9.78 | 33 | 293743 | 1780 | 46390506 |
Haemolysis | 13.46 | 9.78 | 11 | 293765 | 6048 | 46386238 |
No adverse event | 13.42 | 9.78 | 144 | 293632 | 34087 | 46358199 |
Breakthrough pain | 13.20 | 9.78 | 25 | 293751 | 1127 | 46391159 |
Atrioventricular block | 13.20 | 9.78 | 14 | 293762 | 6797 | 46385489 |
Arthralgia | 13.15 | 9.78 | 2054 | 291722 | 362549 | 46029737 |
Internal hernia | 13.14 | 9.78 | 6 | 293770 | 35 | 46392251 |
Blood pressure increased | 13.13 | 9.78 | 657 | 293119 | 126009 | 46266277 |
Cervical spinal stenosis | 13.09 | 9.78 | 34 | 293742 | 1901 | 46390385 |
Glycosylated haemoglobin decreased | 13.07 | 9.78 | 16 | 293760 | 488 | 46391798 |
Wound | 13.05 | 9.78 | 190 | 293586 | 42612 | 46349674 |
Foot fracture | 13.00 | 9.78 | 184 | 293592 | 19398 | 46372888 |
Forced expiratory volume decreased | 13.00 | 9.78 | 8 | 293768 | 5096 | 46387190 |
Gastroenteritis | 12.98 | 9.78 | 94 | 293682 | 24125 | 46368161 |
Postmortem blood drug level increased | 12.98 | 9.78 | 15 | 293761 | 430 | 46391856 |
Hypocalcaemia | 12.93 | 9.78 | 107 | 293669 | 26678 | 46365608 |
Unintended pregnancy | 12.92 | 9.78 | 10 | 293766 | 5650 | 46386636 |
Blood creatine phosphokinase increased | 12.83 | 9.78 | 112 | 293664 | 27612 | 46364674 |
Enterocolitis | 12.73 | 9.78 | 12 | 293764 | 6156 | 46386130 |
Movement disorder | 12.71 | 9.78 | 162 | 293614 | 16687 | 46375599 |
Sinusitis | 12.71 | 9.78 | 677 | 293099 | 129091 | 46263195 |
Eyelid oedema | 12.69 | 9.78 | 29 | 293747 | 10328 | 46381958 |
Peripheral nerve operation | 12.67 | 9.78 | 4 | 293772 | 6 | 46392280 |
Cervicogenic headache | 12.67 | 9.78 | 4 | 293772 | 6 | 46392280 |
Haematotoxicity | 12.61 | 9.78 | 15 | 293761 | 6918 | 46385368 |
Phobia | 12.50 | 9.78 | 13 | 293763 | 330 | 46391956 |
Road traffic accident | 12.45 | 9.78 | 214 | 293562 | 23477 | 46368809 |
Lymphoma | 12.42 | 9.78 | 27 | 293749 | 9786 | 46382500 |
Skin necrosis | 12.33 | 9.78 | 22 | 293754 | 8582 | 46383704 |
Arrhythmia | 12.32 | 9.78 | 150 | 293626 | 34691 | 46357595 |
Adverse drug reaction | 12.31 | 9.78 | 366 | 293410 | 43996 | 46348290 |
Heteroplasia | 12.30 | 9.78 | 4 | 293772 | 7 | 46392279 |
Turbinectomy | 12.22 | 9.78 | 3 | 293773 | 0 | 46392286 |
Muscle relaxant drug level above therapeutic | 12.22 | 9.78 | 3 | 293773 | 0 | 46392286 |
Premature ageing | 12.22 | 9.78 | 3 | 293773 | 0 | 46392286 |
CSF neutrophil count increased | 12.22 | 9.78 | 3 | 293773 | 0 | 46392286 |
Bradyphrenia | 12.22 | 9.78 | 74 | 293702 | 6156 | 46386130 |
Schizophrenia | 12.20 | 9.78 | 22 | 293754 | 8546 | 46383740 |
Dysgraphia | 12.18 | 9.78 | 42 | 293734 | 2750 | 46389536 |
Injection site atrophy | 12.12 | 9.78 | 16 | 293760 | 527 | 46391759 |
Somnambulism | 11.98 | 9.78 | 63 | 293713 | 4974 | 46387312 |
Infection | 11.97 | 9.78 | 703 | 293073 | 132889 | 46259397 |
Lymphoedema | 11.97 | 9.78 | 94 | 293682 | 8518 | 46383768 |
Asthenia | 11.96 | 9.78 | 2177 | 291599 | 308898 | 46083388 |
Narcolepsy | 11.88 | 9.78 | 24 | 293752 | 1135 | 46391151 |
Drug abuser | 11.88 | 9.78 | 46 | 293730 | 3187 | 46389099 |
Altered state of consciousness | 11.86 | 9.78 | 92 | 293684 | 23256 | 46369030 |
Weight increased | 11.83 | 9.78 | 1195 | 292581 | 163278 | 46229008 |
Acute generalised exanthematous pustulosis | 11.80 | 9.78 | 26 | 293750 | 9379 | 46382907 |
Withdrawal catatonia | 11.78 | 9.78 | 6 | 293770 | 46 | 46392240 |
Spinal cord injury | 11.78 | 9.78 | 16 | 293760 | 542 | 46391744 |
Depressed level of consciousness | 11.75 | 9.78 | 387 | 293389 | 47182 | 46345104 |
Lung adenocarcinoma stage I | 11.74 | 9.78 | 5 | 293771 | 24 | 46392262 |
Arteriovenous malformation | 11.73 | 9.78 | 25 | 293751 | 1228 | 46391058 |
Pollakiuria | 11.63 | 9.78 | 216 | 293560 | 24045 | 46368241 |
Peritonitis bacterial | 11.63 | 9.78 | 23 | 293753 | 8630 | 46383656 |
Cholecystitis chronic | 11.61 | 9.78 | 31 | 293745 | 10468 | 46381818 |
Shock | 11.61 | 9.78 | 85 | 293691 | 21760 | 46370526 |
Food allergy | 11.58 | 9.78 | 16 | 293760 | 6917 | 46385369 |
Burns second degree | 11.53 | 9.78 | 18 | 293758 | 693 | 46391593 |
Soft tissue disorder | 11.47 | 9.78 | 6 | 293770 | 4180 | 46388106 |
Copper deficiency | 11.46 | 9.78 | 6 | 293770 | 49 | 46392237 |
Concomitant disease aggravated | 11.44 | 9.78 | 20 | 293756 | 7862 | 46384424 |
Empty sella syndrome | 11.41 | 9.78 | 5 | 293771 | 26 | 46392260 |
Haemangioma of skin | 11.40 | 9.78 | 12 | 293764 | 309 | 46391977 |
Laryngeal oedema | 11.39 | 9.78 | 10 | 293766 | 5309 | 46386977 |
Upper airway resistance syndrome | 11.35 | 9.78 | 4 | 293772 | 10 | 46392276 |
Ankylosing spondylitis | 11.35 | 9.78 | 77 | 293699 | 6660 | 46385626 |
Septic encephalopathy | 11.31 | 9.78 | 7 | 293769 | 81 | 46392205 |
JC polyomavirus test positive | 11.25 | 9.78 | 21 | 293755 | 936 | 46391350 |
Disease progression | 11.19 | 9.78 | 465 | 293311 | 90835 | 46301451 |
Complication of device removal | 11.15 | 9.78 | 4 | 293772 | 3486 | 46388800 |
Electroencephalogram abnormal | 11.12 | 9.78 | 50 | 293726 | 3704 | 46388582 |
Brain malformation | 11.11 | 9.78 | 5 | 293771 | 28 | 46392258 |
Porphyria | 11.06 | 9.78 | 8 | 293768 | 122 | 46392164 |
Hypomagnesaemia | 11.06 | 9.78 | 88 | 293688 | 22122 | 46370164 |
Panic attack | 11.06 | 9.78 | 184 | 293592 | 20058 | 46372228 |
Toe operation | 11.05 | 9.78 | 16 | 293760 | 576 | 46391710 |
Hypertension | 10.96 | 9.78 | 1075 | 292701 | 195281 | 46197005 |
Pneumonitis | 10.96 | 9.78 | 120 | 293656 | 28300 | 46363986 |
Disorientation | 10.90 | 9.78 | 307 | 293469 | 36611 | 46355675 |
Myocarditis | 10.90 | 9.78 | 20 | 293756 | 7719 | 46384567 |
Hepatitis acute | 10.90 | 9.78 | 22 | 293754 | 8192 | 46384094 |
Connective tissue inflammation | 10.88 | 9.78 | 6 | 293770 | 55 | 46392231 |
Acne | 10.83 | 9.78 | 77 | 293699 | 19842 | 46372444 |
Confusional arousal | 10.82 | 9.78 | 7 | 293769 | 88 | 46392198 |
Lymphadenopathy | 10.79 | 9.78 | 147 | 293629 | 33341 | 46358945 |
Metastases to lung | 10.79 | 9.78 | 33 | 293743 | 10663 | 46381623 |
Tachypnoea | 10.75 | 9.78 | 50 | 293726 | 14301 | 46377985 |
Uveitis | 10.75 | 9.78 | 24 | 293752 | 8617 | 46383669 |
Walking aid user | 10.71 | 9.78 | 59 | 293717 | 4741 | 46387545 |
Femoral artery dissection | 10.70 | 9.78 | 5 | 293771 | 31 | 46392255 |
Hepatitis fulminant | 10.70 | 9.78 | 4 | 293772 | 3398 | 46388888 |
Laryngeal dyspnoea | 10.69 | 9.78 | 8 | 293768 | 129 | 46392157 |
Pseudomonas infection | 10.65 | 9.78 | 29 | 293747 | 9729 | 46382557 |
Pulmonary arterial hypertension | 10.60 | 9.78 | 108 | 293668 | 25820 | 46366466 |
Muscle injury | 10.60 | 9.78 | 9 | 293767 | 4857 | 46387429 |
Gastrointestinal inflammation | 10.60 | 9.78 | 7 | 293769 | 4294 | 46387992 |
Inflammation | 10.58 | 9.78 | 230 | 293546 | 48551 | 46343735 |
Dermatitis bullous | 10.55 | 9.78 | 20 | 293756 | 7623 | 46384663 |
Plasma cell myeloma | 10.52 | 9.78 | 360 | 293416 | 44118 | 46348168 |
Lip oedema | 10.50 | 9.78 | 4 | 293772 | 3360 | 46388926 |
Upper gastrointestinal haemorrhage | 10.47 | 9.78 | 62 | 293714 | 16676 | 46375610 |
Infective pulmonary exacerbation of cystic fibrosis | 10.44 | 9.78 | 34 | 293742 | 10773 | 46381513 |
Ischaemic stroke | 10.43 | 9.78 | 62 | 293714 | 16660 | 46375626 |
Hypoxic-ischaemic encephalopathy | 10.42 | 9.78 | 52 | 293724 | 4021 | 46388265 |
Right ventricular failure | 10.40 | 9.78 | 59 | 293717 | 16034 | 46376252 |
Toxicologic test abnormal | 10.38 | 9.78 | 17 | 293759 | 682 | 46391604 |
Gastric bypass | 10.37 | 9.78 | 25 | 293751 | 1334 | 46390952 |
Skin toxicity | 10.37 | 9.78 | 5 | 293771 | 3649 | 46388637 |
Osteopenia | 10.33 | 9.78 | 157 | 293619 | 16804 | 46375482 |
Radiculopathy | 10.28 | 9.78 | 60 | 293716 | 4925 | 46387361 |
Metastases to bone | 10.28 | 9.78 | 66 | 293710 | 17410 | 46374876 |
Bladder disorder | 10.25 | 9.78 | 78 | 293698 | 7000 | 46385286 |
Stress cardiomyopathy | 10.20 | 9.78 | 21 | 293755 | 7763 | 46384523 |
International normalised ratio increased | 10.19 | 9.78 | 221 | 293555 | 46662 | 46345624 |
Naevus haemorrhage | 10.18 | 9.78 | 7 | 293769 | 98 | 46392188 |
Subarachnoid haemorrhage | 10.15 | 9.78 | 36 | 293740 | 11117 | 46381169 |
Micturition urgency | 10.14 | 9.78 | 84 | 293692 | 7733 | 46384553 |
Malignant polyp | 10.12 | 9.78 | 9 | 293767 | 187 | 46392099 |
Pathogen resistance | 10.11 | 9.78 | 14 | 293762 | 6046 | 46386240 |
Accidental overdose | 10.09 | 9.78 | 180 | 293596 | 19886 | 46372400 |
Sciatica | 10.06 | 9.78 | 172 | 293604 | 18848 | 46373438 |
Dry eye | 10.06 | 9.78 | 256 | 293520 | 30066 | 46362220 |
Drug screen false positive | 10.01 | 9.78 | 19 | 293757 | 858 | 46391428 |
Substance use | 9.99 | 9.78 | 13 | 293763 | 422 | 46391864 |
Blood potassium increased | 9.93 | 9.78 | 156 | 293620 | 16811 | 46375475 |
Bronchospasm | 9.92 | 9.78 | 58 | 293718 | 15649 | 46376637 |
Pruritus | 9.90 | 9.78 | 1355 | 292421 | 240997 | 46151289 |
Parapsoriasis | 9.89 | 9.78 | 7 | 293769 | 103 | 46392183 |
Normal newborn | 9.87 | 9.78 | 14 | 293762 | 5987 | 46386299 |
Osteoporosis | 9.84 | 9.78 | 188 | 293588 | 40420 | 46351866 |
Cystitis haemorrhagic | 9.84 | 9.78 | 5 | 293771 | 3542 | 46388744 |
Pulmonary toxicity | 9.84 | 9.78 | 9 | 293767 | 4684 | 46387602 |
Sudden death | 9.82 | 9.78 | 29 | 293747 | 9475 | 46382811 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 988.10 | 10.22 | 1509 | 159969 | 67010 | 29723990 |
Drug ineffective for unapproved indication | 536.26 | 10.22 | 455 | 161023 | 10425 | 29780575 |
Completed suicide | 312.99 | 10.22 | 1211 | 160267 | 98281 | 29692719 |
Myoclonus | 224.37 | 10.22 | 316 | 161162 | 12996 | 29778004 |
Neuropathy peripheral | 168.02 | 10.22 | 789 | 160689 | 69686 | 29721314 |
Somnolence | 157.08 | 10.22 | 975 | 160503 | 95788 | 29695212 |
Toxicity to various agents | 139.03 | 10.22 | 1513 | 159965 | 175670 | 29615330 |
Drug withdrawal syndrome | 138.11 | 10.22 | 320 | 161158 | 19489 | 29771511 |
Interstitial lung disease | 132.69 | 10.22 | 80 | 161398 | 60117 | 29730883 |
Pain | 125.77 | 10.22 | 1453 | 160025 | 171188 | 29619812 |
Fall | 125.14 | 10.22 | 1514 | 159964 | 180358 | 29610642 |
Multiple sclerosis relapse | 111.74 | 10.22 | 206 | 161272 | 10656 | 29780344 |
Sedation | 104.94 | 10.22 | 256 | 161222 | 16117 | 29774883 |
Mental status changes | 101.75 | 10.22 | 433 | 161045 | 36646 | 29754354 |
Neuralgia | 100.83 | 10.22 | 193 | 161285 | 10273 | 29780727 |
Febrile neutropenia | 93.89 | 10.22 | 280 | 161198 | 106413 | 29684587 |
Memory impairment | 90.57 | 10.22 | 419 | 161059 | 36755 | 29754245 |
Hypoaesthesia | 87.61 | 10.22 | 546 | 160932 | 53684 | 29737316 |
Cytomegalovirus infection | 87.30 | 10.22 | 12 | 161466 | 23662 | 29767338 |
Confusional state | 84.29 | 10.22 | 1103 | 160375 | 133731 | 29657269 |
Tremor | 84.12 | 10.22 | 694 | 160784 | 74669 | 29716331 |
Hepatic function abnormal | 82.70 | 10.22 | 63 | 161415 | 41882 | 29749118 |
Pain in extremity | 80.70 | 10.22 | 929 | 160549 | 109292 | 29681708 |
Depression | 80.57 | 10.22 | 793 | 160685 | 89644 | 29701356 |
Cardiac failure | 78.46 | 10.22 | 212 | 161266 | 83206 | 29707794 |
Drug dependence | 78.37 | 10.22 | 273 | 161205 | 21022 | 29769978 |
Anaemia | 78.04 | 10.22 | 731 | 160747 | 207261 | 29583739 |
Withdrawal syndrome | 76.50 | 10.22 | 180 | 161298 | 11070 | 29779930 |
Multiple organ dysfunction syndrome | 76.35 | 10.22 | 141 | 161337 | 63346 | 29727654 |
Gait disturbance | 75.26 | 10.22 | 673 | 160805 | 74104 | 29716896 |
Drug abuse | 74.74 | 10.22 | 723 | 160755 | 81349 | 29709651 |
Insomnia | 73.92 | 10.22 | 799 | 160679 | 92537 | 29698463 |
Suicidal ideation | 70.27 | 10.22 | 382 | 161096 | 35732 | 29755268 |
Pyrexia | 68.36 | 10.22 | 1147 | 160331 | 293342 | 29497658 |
Thrombocytopenia | 65.97 | 10.22 | 450 | 161028 | 136594 | 29654406 |
Euphoric mood | 65.21 | 10.22 | 97 | 161381 | 4193 | 29786807 |
Balance disorder | 65.03 | 10.22 | 377 | 161101 | 36116 | 29754884 |
Product complaint | 63.38 | 10.22 | 113 | 161365 | 5693 | 29785307 |
Renal impairment | 63.01 | 10.22 | 237 | 161241 | 83947 | 29707053 |
Accidental death | 62.24 | 10.22 | 66 | 161412 | 2013 | 29788987 |
Drug resistance | 61.93 | 10.22 | 16 | 161462 | 20117 | 29770883 |
Muscle spasms | 61.90 | 10.22 | 577 | 160901 | 64261 | 29726739 |
Respiratory arrest | 58.62 | 10.22 | 312 | 161166 | 28946 | 29762054 |
Obsessive-compulsive disorder | 57.81 | 10.22 | 90 | 161388 | 4051 | 29786949 |
General physical health deterioration | 52.75 | 10.22 | 319 | 161159 | 99625 | 29691375 |
C-reactive protein increased | 50.98 | 10.22 | 98 | 161380 | 43375 | 29747625 |
Burning sensation | 48.79 | 10.22 | 197 | 161281 | 16277 | 29774723 |
Feeling abnormal | 48.72 | 10.22 | 494 | 160984 | 56262 | 29734738 |
Anxiety | 48.70 | 10.22 | 717 | 160761 | 89154 | 29701846 |
Disseminated intravascular coagulation | 48.08 | 10.22 | 30 | 161448 | 22141 | 29768859 |
Neutropenia | 47.58 | 10.22 | 453 | 161025 | 128087 | 29662913 |
Alanine aminotransferase increased | 47.58 | 10.22 | 222 | 161256 | 74054 | 29716946 |
Amnesia | 45.78 | 10.22 | 255 | 161223 | 24066 | 29766934 |
Dizziness | 45.06 | 10.22 | 1372 | 160106 | 193537 | 29597463 |
Back disorder | 44.17 | 10.22 | 99 | 161379 | 5895 | 29785105 |
Bone marrow failure | 43.55 | 10.22 | 58 | 161420 | 29727 | 29761273 |
Septic shock | 43.21 | 10.22 | 186 | 161292 | 63421 | 29727579 |
Therapeutic product effect variable | 43.19 | 10.22 | 45 | 161433 | 1344 | 29789656 |
Paraesthesia | 42.47 | 10.22 | 464 | 161014 | 53863 | 29737137 |
Vision blurred | 42.36 | 10.22 | 377 | 161101 | 41439 | 29749561 |
Mucosal inflammation | 41.97 | 10.22 | 62 | 161416 | 30432 | 29760568 |
Multiple sclerosis | 41.73 | 10.22 | 109 | 161369 | 7158 | 29783842 |
Prescription drug used without a prescription | 39.45 | 10.22 | 41 | 161437 | 1221 | 29789779 |
Inadequate analgesia | 39.41 | 10.22 | 60 | 161418 | 2648 | 29788352 |
Congenital multiplex arthrogryposis | 39.29 | 10.22 | 13 | 161465 | 31 | 29790969 |
Dyspnoea | 38.22 | 10.22 | 1441 | 160037 | 331854 | 29459146 |
Overdose | 38.18 | 10.22 | 653 | 160825 | 83684 | 29707316 |
Hepatic failure | 37.97 | 10.22 | 79 | 161399 | 33964 | 29757036 |
Drug reaction with eosinophilia and systemic symptoms | 37.22 | 10.22 | 60 | 161418 | 28428 | 29762572 |
Dysarthria | 36.27 | 10.22 | 285 | 161193 | 30205 | 29760795 |
Disinhibition | 35.28 | 10.22 | 48 | 161430 | 1909 | 29789091 |
Muscle spasticity | 35.26 | 10.22 | 83 | 161395 | 5105 | 29785895 |
Myokymia | 35.15 | 10.22 | 14 | 161464 | 66 | 29790934 |
Parasomnia | 34.85 | 10.22 | 21 | 161457 | 273 | 29790727 |
Hypokalaemia | 33.94 | 10.22 | 147 | 161331 | 50045 | 29740955 |
Haemophagocytic lymphohistiocytosis | 33.75 | 10.22 | 6 | 161472 | 9785 | 29781215 |
Diabetic neuropathy | 33.31 | 10.22 | 69 | 161409 | 3890 | 29787110 |
Jaundice | 33.27 | 10.22 | 79 | 161399 | 32407 | 29758593 |
Full blood count decreased | 33.13 | 10.22 | 170 | 161308 | 15547 | 29775453 |
Drug tolerance | 33.03 | 10.22 | 49 | 161429 | 2113 | 29788887 |
Renal failure | 32.91 | 10.22 | 493 | 160985 | 128473 | 29662527 |
Cerebral haemorrhage | 32.87 | 10.22 | 81 | 161397 | 32806 | 29758194 |
Back pain | 32.85 | 10.22 | 754 | 160724 | 101842 | 29689158 |
Hallucination | 32.55 | 10.22 | 406 | 161072 | 48653 | 29742347 |
Nightmare | 32.31 | 10.22 | 140 | 161338 | 11936 | 29779064 |
Blood bilirubin increased | 32.28 | 10.22 | 96 | 161382 | 36540 | 29754460 |
Antipsychotic drug level below therapeutic | 31.59 | 10.22 | 38 | 161440 | 1334 | 29789666 |
Malignant neoplasm progression | 31.53 | 10.22 | 244 | 161234 | 72043 | 29718957 |
Atrial fibrillation | 31.27 | 10.22 | 403 | 161075 | 107721 | 29683279 |
Anorgasmia | 30.86 | 10.22 | 26 | 161452 | 589 | 29790411 |
Melaena | 30.80 | 10.22 | 82 | 161396 | 32355 | 29758645 |
Hyperreflexia | 30.66 | 10.22 | 55 | 161423 | 2784 | 29788216 |
Muscle twitching | 30.39 | 10.22 | 105 | 161373 | 8050 | 29782950 |
Sciatica | 30.18 | 10.22 | 77 | 161401 | 4984 | 29786016 |
Peripheral swelling | 29.89 | 10.22 | 479 | 160999 | 60595 | 29730405 |
Acute kidney injury | 29.80 | 10.22 | 1191 | 160287 | 272651 | 29518349 |
Sweat gland disorder | 29.36 | 10.22 | 14 | 161464 | 109 | 29790891 |
Product dose omission issue | 29.20 | 10.22 | 673 | 160805 | 90958 | 29700042 |
Peritonitis | 28.89 | 10.22 | 44 | 161434 | 21331 | 29769669 |
Nerve injury | 28.72 | 10.22 | 55 | 161423 | 2928 | 29788072 |
Infusion related reaction | 28.54 | 10.22 | 117 | 161361 | 40447 | 29750553 |
Trigeminal neuralgia | 28.03 | 10.22 | 29 | 161449 | 859 | 29790141 |
Off label use | 27.81 | 10.22 | 1081 | 160397 | 248209 | 29542791 |
Aspartate aminotransferase increased | 27.69 | 10.22 | 214 | 161264 | 63208 | 29727792 |
Asterixis | 27.57 | 10.22 | 34 | 161444 | 1225 | 29789775 |
Bronchopulmonary aspergillosis | 27.51 | 10.22 | 16 | 161462 | 12268 | 29778732 |
Tooth disorder | 27.48 | 10.22 | 110 | 161368 | 9051 | 29781949 |
Fatigue | 27.28 | 10.22 | 2043 | 159435 | 318630 | 29472370 |
Increased appetite | 27.04 | 10.22 | 79 | 161399 | 5538 | 29785462 |
Ascites | 26.94 | 10.22 | 101 | 161377 | 35820 | 29755180 |
Contraindicated product administered | 26.80 | 10.22 | 32 | 161446 | 17199 | 29773801 |
Foetal exposure during pregnancy | 26.79 | 10.22 | 105 | 161373 | 36766 | 29754234 |
Neutrophil count decreased | 26.52 | 10.22 | 128 | 161350 | 42326 | 29748674 |
Aspergillus infection | 26.35 | 10.22 | 11 | 161467 | 10203 | 29780797 |
Adverse drug reaction | 26.24 | 10.22 | 214 | 161264 | 22931 | 29768069 |
Graft versus host disease | 26.08 | 10.22 | 11 | 161467 | 10139 | 29780861 |
Delirium tremens | 25.80 | 10.22 | 22 | 161456 | 507 | 29790493 |
Bradyphrenia | 25.49 | 10.22 | 62 | 161416 | 3895 | 29787105 |
Spinal operation | 25.47 | 10.22 | 45 | 161433 | 2251 | 29788749 |
Pneumocystis jirovecii pneumonia | 25.37 | 10.22 | 33 | 161445 | 17087 | 29773913 |
Nervousness | 25.19 | 10.22 | 128 | 161350 | 11660 | 29779340 |
Proteinuria | 25.10 | 10.22 | 30 | 161448 | 16115 | 29774885 |
Cholestasis | 24.51 | 10.22 | 62 | 161416 | 24888 | 29766112 |
Bradypnoea | 24.41 | 10.22 | 40 | 161438 | 1881 | 29789119 |
Hyperaesthesia | 24.11 | 10.22 | 57 | 161421 | 3516 | 29787484 |
Respiratory depression | 23.95 | 10.22 | 124 | 161354 | 11379 | 29779621 |
Depressed level of consciousness | 23.94 | 10.22 | 313 | 161165 | 37909 | 29753091 |
Suicidal behaviour | 23.94 | 10.22 | 33 | 161445 | 1329 | 29789671 |
Localised infection | 23.86 | 10.22 | 141 | 161337 | 13596 | 29777404 |
Colitis | 23.54 | 10.22 | 86 | 161392 | 30734 | 29760266 |
Intervertebral disc degeneration | 23.53 | 10.22 | 72 | 161406 | 5179 | 29785821 |
Ataxia | 23.48 | 10.22 | 123 | 161355 | 11339 | 29779661 |
Personality change | 23.41 | 10.22 | 66 | 161412 | 4534 | 29786466 |
Eosinophilia | 23.41 | 10.22 | 53 | 161425 | 22107 | 29768893 |
Lethargy | 23.26 | 10.22 | 320 | 161158 | 39199 | 29751801 |
Anger | 23.24 | 10.22 | 120 | 161358 | 11000 | 29780000 |
Constipation | 23.22 | 10.22 | 784 | 160694 | 112122 | 29678878 |
Angioedema | 23.06 | 10.22 | 101 | 161377 | 34283 | 29756717 |
Gamma-glutamyltransferase increased | 23.01 | 10.22 | 81 | 161397 | 29269 | 29761731 |
Acute myocardial infarction | 22.93 | 10.22 | 179 | 161299 | 52760 | 29738240 |
Venoocclusive liver disease | 22.91 | 10.22 | 4 | 161474 | 6609 | 29784391 |
Gait inability | 22.89 | 10.22 | 177 | 161301 | 18664 | 29772336 |
Antidepressant drug level above therapeutic | 22.68 | 10.22 | 13 | 161465 | 153 | 29790847 |
Muscular weakness | 22.66 | 10.22 | 475 | 161003 | 63170 | 29727830 |
Cerebral infarction | 22.60 | 10.22 | 70 | 161408 | 26303 | 29764697 |
Affective disorder | 22.53 | 10.22 | 51 | 161427 | 3057 | 29787943 |
Cholangitis | 22.51 | 10.22 | 7 | 161471 | 7795 | 29783205 |
Gastrointestinal haemorrhage | 22.31 | 10.22 | 316 | 161162 | 83130 | 29707870 |
Erythema | 22.26 | 10.22 | 289 | 161189 | 77162 | 29713838 |
Coordination abnormal | 22.14 | 10.22 | 88 | 161390 | 7217 | 29783783 |
Transplant rejection | 22.06 | 10.22 | 11 | 161467 | 9195 | 29781805 |
Rheumatoid arthritis | 21.97 | 10.22 | 131 | 161347 | 41066 | 29749934 |
Neonatal toxicity | 21.95 | 10.22 | 8 | 161470 | 28 | 29790972 |
Haematuria | 21.63 | 10.22 | 147 | 161331 | 44687 | 29746313 |
Acute myeloid leukaemia | 21.62 | 10.22 | 40 | 161438 | 17966 | 29773034 |
Mood altered | 21.58 | 10.22 | 95 | 161383 | 8155 | 29782845 |
Toxic epidermal necrolysis | 21.41 | 10.22 | 40 | 161438 | 17900 | 29773100 |
Pneumonitis | 21.37 | 10.22 | 76 | 161402 | 27378 | 29763622 |
Facial pain | 21.24 | 10.22 | 36 | 161442 | 1741 | 29789259 |
Colitis ulcerative | 21.20 | 10.22 | 28 | 161450 | 14406 | 29776594 |
Encephalopathy neonatal | 21.12 | 10.22 | 8 | 161470 | 32 | 29790968 |
Hypernatraemia | 21.09 | 10.22 | 7 | 161471 | 7477 | 29783523 |
Hallucination, visual | 21.06 | 10.22 | 154 | 161324 | 15959 | 29775041 |
Haematotoxicity | 20.79 | 10.22 | 4 | 161474 | 6166 | 29784834 |
Plasma cell myeloma | 20.69 | 10.22 | 404 | 161074 | 53058 | 29737942 |
Hypometabolism | 20.56 | 10.22 | 8 | 161470 | 35 | 29790965 |
Labelled drug-drug interaction medication error | 20.54 | 10.22 | 16 | 161462 | 10522 | 29780478 |
Feeding intolerance | 20.43 | 10.22 | 9 | 161469 | 57 | 29790943 |
Acute respiratory distress syndrome | 20.32 | 10.22 | 62 | 161416 | 23410 | 29767590 |
Transaminases increased | 20.28 | 10.22 | 62 | 161416 | 23395 | 29767605 |
Sleep apnoea syndrome | 20.28 | 10.22 | 158 | 161320 | 16699 | 29774301 |
Pathogen resistance | 20.23 | 10.22 | 10 | 161468 | 8400 | 29782600 |
Myocardial infarction | 20.21 | 10.22 | 519 | 160959 | 125106 | 29665894 |
Impaired driving ability | 20.16 | 10.22 | 43 | 161435 | 2475 | 29788525 |
Anaphylactic reaction | 20.13 | 10.22 | 80 | 161398 | 27902 | 29763098 |
Phantom limb syndrome | 20.12 | 10.22 | 15 | 161463 | 283 | 29790717 |
Metabolic acidosis | 20.04 | 10.22 | 119 | 161359 | 37342 | 29753658 |
Circulatory collapse | 20.03 | 10.22 | 50 | 161428 | 20164 | 29770836 |
Epistaxis | 19.88 | 10.22 | 186 | 161292 | 52795 | 29738205 |
Erectile dysfunction | 19.79 | 10.22 | 166 | 161312 | 17936 | 29773064 |
Myocarditis | 19.77 | 10.22 | 15 | 161463 | 9996 | 29781004 |
Hepatic enzyme increased | 19.77 | 10.22 | 103 | 161375 | 33391 | 29757609 |
Joint hyperextension | 19.71 | 10.22 | 8 | 161470 | 40 | 29790960 |
Binocular eye movement disorder | 19.55 | 10.22 | 8 | 161470 | 41 | 29790959 |
Pancytopenia | 19.38 | 10.22 | 332 | 161146 | 84720 | 29706280 |
Rash maculo-papular | 19.36 | 10.22 | 71 | 161407 | 25347 | 29765653 |
Asthma | 19.30 | 10.22 | 115 | 161363 | 36059 | 29754941 |
Cognitive disorder | 19.27 | 10.22 | 204 | 161274 | 23486 | 29767514 |
Pleural effusion | 19.26 | 10.22 | 282 | 161196 | 73784 | 29717216 |
Hostility | 19.24 | 10.22 | 24 | 161454 | 875 | 29790125 |
Dyskinesia | 19.18 | 10.22 | 191 | 161287 | 21643 | 29769357 |
Treatment failure | 19.17 | 10.22 | 109 | 161369 | 34570 | 29756430 |
Conversion disorder | 19.12 | 10.22 | 16 | 161462 | 359 | 29790641 |
Cerebral disorder | 19.11 | 10.22 | 41 | 161437 | 2369 | 29788631 |
Leukopenia | 19.05 | 10.22 | 202 | 161276 | 55957 | 29735043 |
Hepatocellular injury | 18.85 | 10.22 | 72 | 161406 | 25399 | 29765601 |
Post transplant lymphoproliferative disorder | 18.84 | 10.22 | 3 | 161475 | 5303 | 29785697 |
Pulmonary alveolar haemorrhage | 18.82 | 10.22 | 6 | 161472 | 6575 | 29784425 |
Disorientation | 18.73 | 10.22 | 255 | 161223 | 31163 | 29759837 |
Restless legs syndrome | 18.64 | 10.22 | 80 | 161398 | 6792 | 29784208 |
Thinking abnormal | 18.60 | 10.22 | 67 | 161411 | 5244 | 29785756 |
Posterior reversible encephalopathy syndrome | 18.58 | 10.22 | 12 | 161466 | 8695 | 29782305 |
Intentional product misuse | 18.52 | 10.22 | 276 | 161202 | 34391 | 29756609 |
Drug eruption | 18.44 | 10.22 | 42 | 161436 | 17484 | 29773516 |
Hyperbilirubinaemia | 18.32 | 10.22 | 40 | 161438 | 16902 | 29774098 |
Feeling drunk | 18.30 | 10.22 | 32 | 161446 | 1587 | 29789413 |
Opisthotonus | 18.29 | 10.22 | 16 | 161462 | 382 | 29790618 |
Precancerous skin lesion | 18.25 | 10.22 | 19 | 161459 | 567 | 29790433 |
Analgesic drug level above therapeutic | 18.05 | 10.22 | 13 | 161465 | 232 | 29790768 |
Infective pulmonary exacerbation of cystic fibrosis | 18.04 | 10.22 | 12 | 161466 | 8560 | 29782440 |
Serotonin syndrome | 17.95 | 10.22 | 161 | 161317 | 17730 | 29773270 |
Fibromyalgia | 17.92 | 10.22 | 42 | 161436 | 2576 | 29788424 |
Metastases to liver | 17.79 | 10.22 | 23 | 161455 | 11942 | 29779058 |
Ear deformity acquired | 17.70 | 10.22 | 5 | 161473 | 5 | 29790995 |
Epstein-Barr virus infection | 17.66 | 10.22 | 7 | 161471 | 6699 | 29784301 |
Cough | 17.65 | 10.22 | 529 | 160949 | 125113 | 29665887 |
Blood creatinine increased | 17.63 | 10.22 | 367 | 161111 | 91008 | 29699992 |
Blood lactate dehydrogenase increased | 17.42 | 10.22 | 55 | 161423 | 20546 | 29770454 |
Musculoskeletal disorder | 17.40 | 10.22 | 62 | 161416 | 4827 | 29786173 |
Hand deformity | 17.38 | 10.22 | 34 | 161444 | 1839 | 29789161 |
Migraine | 17.37 | 10.22 | 124 | 161354 | 12750 | 29778250 |
Nephropathy toxic | 17.37 | 10.22 | 19 | 161459 | 10620 | 29780380 |
Seizure | 17.34 | 10.22 | 672 | 160806 | 97803 | 29693197 |
Intervertebral disc protrusion | 17.31 | 10.22 | 97 | 161381 | 9174 | 29781826 |
Blood creatine phosphokinase increased | 17.29 | 10.22 | 152 | 161326 | 43696 | 29747304 |
Mental impairment | 17.28 | 10.22 | 97 | 161381 | 9180 | 29781820 |
Liver disorder | 17.20 | 10.22 | 92 | 161386 | 29630 | 29761370 |
Delirium | 17.08 | 10.22 | 311 | 161167 | 40320 | 29750680 |
Hepatocellular carcinoma | 17.01 | 10.22 | 16 | 161462 | 9594 | 29781406 |
Tumour lysis syndrome | 16.96 | 10.22 | 27 | 161451 | 12858 | 29778142 |
Idiopathic neutropenia | 16.91 | 10.22 | 4 | 161474 | 0 | 29791000 |
Agranulocytosis | 16.90 | 10.22 | 61 | 161417 | 21881 | 29769119 |
Haemolysis | 16.79 | 10.22 | 9 | 161469 | 7222 | 29783778 |
Stomatitis | 16.64 | 10.22 | 125 | 161353 | 37154 | 29753846 |
Tubulointerstitial nephritis | 16.40 | 10.22 | 46 | 161432 | 17845 | 29773155 |
Haemoglobin decreased | 16.37 | 10.22 | 479 | 160999 | 113619 | 29677381 |
Immune reconstitution inflammatory syndrome | 16.29 | 10.22 | 15 | 161463 | 9086 | 29781914 |
Urinary incontinence | 16.27 | 10.22 | 151 | 161327 | 16789 | 29774211 |
Osteomyelitis | 16.24 | 10.22 | 135 | 161343 | 14546 | 29776454 |
Heat exhaustion | 16.07 | 10.22 | 9 | 161469 | 101 | 29790899 |
Aggression | 16.05 | 10.22 | 284 | 161194 | 36623 | 29754377 |
Agitation | 15.94 | 10.22 | 393 | 161085 | 53680 | 29737320 |
Appendicolith | 15.75 | 10.22 | 22 | 161456 | 897 | 29790103 |
Metabolic encephalopathy | 15.73 | 10.22 | 51 | 161427 | 3784 | 29787216 |
Shock haemorrhagic | 15.69 | 10.22 | 18 | 161460 | 9847 | 29781153 |
Gingival atrophy | 15.68 | 10.22 | 7 | 161471 | 46 | 29790954 |
Acute coronary syndrome | 15.56 | 10.22 | 31 | 161447 | 13542 | 29777458 |
Ischaemic stroke | 15.55 | 10.22 | 41 | 161437 | 16234 | 29774766 |
Sopor | 15.50 | 10.22 | 107 | 161371 | 10884 | 29780116 |
Diplopia | 15.43 | 10.22 | 127 | 161351 | 13645 | 29777355 |
Artery dissection | 15.41 | 10.22 | 9 | 161469 | 110 | 29790890 |
Nephrotic syndrome | 15.37 | 10.22 | 9 | 161469 | 6876 | 29784124 |
Thrombosis | 15.29 | 10.22 | 316 | 161162 | 41915 | 29749085 |
Quality of life decreased | 15.25 | 10.22 | 45 | 161433 | 3172 | 29787828 |
Dysphemia | 15.12 | 10.22 | 28 | 161450 | 1453 | 29789547 |
Herpes zoster | 15.07 | 10.22 | 236 | 161242 | 29707 | 29761293 |
Pulmonary toxicity | 15.07 | 10.22 | 3 | 161475 | 4513 | 29786487 |
Drug screen negative | 15.01 | 10.22 | 12 | 161466 | 252 | 29790748 |
Encephalitis | 14.96 | 10.22 | 8 | 161470 | 6428 | 29784572 |
Prescribed overdose | 14.95 | 10.22 | 88 | 161390 | 8473 | 29782527 |
Schizophrenia | 14.95 | 10.22 | 16 | 161462 | 9032 | 29781968 |
Ventricular tachycardia | 14.87 | 10.22 | 72 | 161406 | 23790 | 29767210 |
Tuberculosis | 14.83 | 10.22 | 13 | 161465 | 8064 | 29782936 |
Body height decreased | 14.72 | 10.22 | 49 | 161429 | 3685 | 29787315 |
Pulmonary tuberculosis | 14.67 | 10.22 | 4 | 161474 | 4853 | 29786147 |
Muscle tightness | 14.67 | 10.22 | 56 | 161422 | 4507 | 29786493 |
Enterocolitis | 14.56 | 10.22 | 9 | 161469 | 6678 | 29784322 |
Rhabdomyolysis | 14.54 | 10.22 | 248 | 161230 | 63332 | 29727668 |
Irritability | 14.53 | 10.22 | 189 | 161289 | 22861 | 29768139 |
Acute hepatic failure | 14.44 | 10.22 | 26 | 161452 | 11801 | 29779199 |
Thoracic vertebral fracture | 14.42 | 10.22 | 27 | 161451 | 1413 | 29789587 |
Back injury | 14.41 | 10.22 | 47 | 161431 | 3498 | 29787502 |
Synovitis | 14.35 | 10.22 | 19 | 161459 | 9764 | 29781236 |
Foot fracture | 14.08 | 10.22 | 52 | 161426 | 4120 | 29786880 |
Hyperkalaemia | 13.98 | 10.22 | 261 | 161217 | 65749 | 29725251 |
Acute pulmonary oedema | 13.92 | 10.22 | 12 | 161466 | 7503 | 29783497 |
Weight increased | 13.85 | 10.22 | 514 | 160964 | 74399 | 29716601 |
Spinal stenosis | 13.81 | 10.22 | 53 | 161425 | 4276 | 29786724 |
Blood pressure decreased | 13.76 | 10.22 | 175 | 161303 | 46900 | 29744100 |
Shock | 13.65 | 10.22 | 70 | 161408 | 22789 | 29768211 |
Blood urea increased | 13.64 | 10.22 | 106 | 161372 | 31275 | 29759725 |
Mucosal atrophy | 13.45 | 10.22 | 7 | 161471 | 67 | 29790933 |
Personality disorder | 13.28 | 10.22 | 23 | 161455 | 1132 | 29789868 |
Free androgen index decreased | 13.20 | 10.22 | 5 | 161473 | 20 | 29790980 |
Foetal disorder | 13.19 | 10.22 | 17 | 161461 | 641 | 29790359 |
Tachycardia | 13.12 | 10.22 | 300 | 161178 | 73439 | 29717561 |
Abnormal sleep-related event | 13.10 | 10.22 | 15 | 161463 | 499 | 29790501 |
Mucormycosis | 13.07 | 10.22 | 6 | 161472 | 5262 | 29785738 |
Mental disorder | 12.97 | 10.22 | 120 | 161358 | 13329 | 29777671 |
Injection site mass | 12.93 | 10.22 | 57 | 161421 | 4896 | 29786104 |
Autoimmune haemolytic anaemia | 12.92 | 10.22 | 3 | 161475 | 4056 | 29786944 |
Lung disorder | 12.89 | 10.22 | 108 | 161370 | 31361 | 29759639 |
Inflammation | 12.85 | 10.22 | 68 | 161410 | 21958 | 29769042 |
Abdominal discomfort | 12.75 | 10.22 | 349 | 161129 | 48442 | 29742558 |
Therapeutic response unexpected | 12.75 | 10.22 | 87 | 161391 | 8816 | 29782184 |
Facial wasting | 12.72 | 10.22 | 9 | 161469 | 156 | 29790844 |
Pancreatic fibrosis | 12.69 | 10.22 | 3 | 161475 | 0 | 29791000 |
Severe myoclonic epilepsy of infancy | 12.69 | 10.22 | 3 | 161475 | 0 | 29791000 |
Nasal odour | 12.69 | 10.22 | 3 | 161475 | 0 | 29791000 |
Left ventricular dysfunction | 12.62 | 10.22 | 17 | 161461 | 8674 | 29782326 |
Dysaesthesia | 12.62 | 10.22 | 33 | 161445 | 2168 | 29788832 |
Hypoosmolar state | 12.62 | 10.22 | 7 | 161471 | 77 | 29790923 |
Rectal haemorrhage | 12.53 | 10.22 | 124 | 161354 | 34815 | 29756185 |
Eye injury | 12.51 | 10.22 | 13 | 161465 | 387 | 29790613 |
Hepatitis | 12.50 | 10.22 | 70 | 161408 | 22286 | 29768714 |
Hypersomnia | 12.49 | 10.22 | 104 | 161374 | 11212 | 29779788 |
Dependence on respirator | 12.48 | 10.22 | 5 | 161473 | 24 | 29790976 |
Palmar-plantar erythrodysaesthesia syndrome | 12.36 | 10.22 | 40 | 161438 | 14830 | 29776170 |
Violence-related symptom | 12.35 | 10.22 | 15 | 161463 | 532 | 29790468 |
Facet joint syndrome | 12.35 | 10.22 | 10 | 161468 | 214 | 29790786 |
Candida infection | 12.31 | 10.22 | 42 | 161436 | 15320 | 29775680 |
Radiculopathy | 12.30 | 10.22 | 37 | 161441 | 2636 | 29788364 |
Hyperuricaemia | 12.30 | 10.22 | 13 | 161465 | 7381 | 29783619 |
Neutrophil count increased | 12.20 | 10.22 | 42 | 161436 | 15281 | 29775719 |
Hypoalbuminaemia | 12.15 | 10.22 | 26 | 161452 | 11066 | 29779934 |
Stevens-Johnson syndrome | 12.12 | 10.22 | 51 | 161427 | 17505 | 29773495 |
Hepatitis B | 12.12 | 10.22 | 9 | 161469 | 6063 | 29784937 |
Dysphoria | 12.11 | 10.22 | 32 | 161446 | 2116 | 29788884 |
Anaphylactic shock | 12.08 | 10.22 | 37 | 161441 | 13956 | 29777044 |
Cytomegalovirus viraemia | 12.08 | 10.22 | 8 | 161470 | 5721 | 29785279 |
Toxic skin eruption | 11.91 | 10.22 | 26 | 161452 | 10989 | 29780011 |
Seborrhoeic keratosis | 11.89 | 10.22 | 20 | 161458 | 961 | 29790039 |
Complex regional pain syndrome | 11.87 | 10.22 | 14 | 161464 | 481 | 29790519 |
Laboratory test abnormal | 11.84 | 10.22 | 145 | 161333 | 17297 | 29773703 |
Pneumothorax | 11.83 | 10.22 | 46 | 161432 | 16147 | 29774853 |
Drug abuser | 11.76 | 10.22 | 51 | 161427 | 4350 | 29786650 |
Hepatotoxicity | 11.74 | 10.22 | 54 | 161424 | 18091 | 29772909 |
Panic disorder | 11.73 | 10.22 | 22 | 161456 | 1153 | 29789847 |
Foetal heart rate disorder | 11.71 | 10.22 | 5 | 161473 | 29 | 29790971 |
Psoriasis | 11.69 | 10.22 | 160 | 161318 | 42346 | 29748654 |
Sensory disturbance | 11.65 | 10.22 | 62 | 161416 | 5749 | 29785251 |
Slow speech | 11.64 | 10.22 | 20 | 161458 | 978 | 29790022 |
Hypertriglyceridaemia | 11.60 | 10.22 | 16 | 161462 | 8082 | 29782918 |
Hyperthyroidism | 11.60 | 10.22 | 16 | 161462 | 8082 | 29782918 |
Mouth ulceration | 11.51 | 10.22 | 25 | 161453 | 10584 | 29780416 |
Drug effective for unapproved indication | 11.50 | 10.22 | 21 | 161457 | 1078 | 29789922 |
Hypotension | 11.49 | 10.22 | 928 | 160550 | 199637 | 29591363 |
Erysipelas | 11.47 | 10.22 | 5 | 161473 | 4519 | 29786481 |
Oesophageal mucosa erythema | 11.44 | 10.22 | 5 | 161473 | 31 | 29790969 |
Haemorrhage intracranial | 11.44 | 10.22 | 42 | 161436 | 14990 | 29776010 |
Acute graft versus host disease in skin | 11.43 | 10.22 | 5 | 161473 | 4511 | 29786489 |
Post herpetic neuralgia | 11.39 | 10.22 | 20 | 161458 | 995 | 29790005 |
Breakthrough pain | 11.39 | 10.22 | 15 | 161463 | 578 | 29790422 |
Swelling | 11.37 | 10.22 | 264 | 161214 | 35711 | 29755289 |
Panic attack | 11.36 | 10.22 | 83 | 161395 | 8598 | 29782402 |
Chronic graft versus host disease | 11.35 | 10.22 | 4 | 161474 | 4115 | 29786885 |
Fracture | 11.32 | 10.22 | 63 | 161415 | 5943 | 29785057 |
Teeth brittle | 11.31 | 10.22 | 6 | 161472 | 60 | 29790940 |
Walking disability | 11.30 | 10.22 | 17 | 161461 | 742 | 29790258 |
Lymphoedema | 11.30 | 10.22 | 43 | 161435 | 3456 | 29787544 |
Dissociative disorder | 11.29 | 10.22 | 8 | 161470 | 139 | 29790861 |
Neck pain | 11.28 | 10.22 | 167 | 161311 | 20777 | 29770223 |
Nerve compression | 11.25 | 10.22 | 37 | 161441 | 2765 | 29788235 |
Lower respiratory tract infection | 11.25 | 10.22 | 91 | 161387 | 26623 | 29764377 |
Incoherent | 11.21 | 10.22 | 48 | 161430 | 4070 | 29786930 |
Hyperfibrinogenaemia | 11.20 | 10.22 | 4 | 161474 | 13 | 29790987 |
Blood alkaline phosphatase increased | 11.19 | 10.22 | 112 | 161366 | 31375 | 29759625 |
Nephrogenic systemic fibrosis | 11.18 | 10.22 | 50 | 161428 | 4321 | 29786679 |
Dependence | 11.07 | 10.22 | 22 | 161456 | 1204 | 29789796 |
Lymphocyte count decreased | 11.02 | 10.22 | 59 | 161419 | 18996 | 29772004 |
Hyperglycaemia | 10.99 | 10.22 | 129 | 161349 | 35071 | 29755929 |
Genital burning sensation | 10.97 | 10.22 | 4 | 161474 | 14 | 29790986 |
Abnormal labour affecting foetus | 10.97 | 10.22 | 4 | 161474 | 14 | 29790986 |
Myelosuppression | 10.96 | 10.22 | 14 | 161464 | 7308 | 29783692 |
Neurogenic bladder | 10.90 | 10.22 | 26 | 161452 | 1613 | 29789387 |
Drug tolerance increased | 10.83 | 10.22 | 12 | 161466 | 385 | 29790615 |
Respiratory disorder | 10.77 | 10.22 | 53 | 161425 | 17441 | 29773559 |
Second primary malignancy | 10.77 | 10.22 | 11 | 161467 | 6345 | 29784655 |
Neck surgery | 10.76 | 10.22 | 11 | 161467 | 321 | 29790679 |
Fear of weight gain | 10.76 | 10.22 | 4 | 161474 | 15 | 29790985 |
Immunosuppressant drug level increased | 10.70 | 10.22 | 6 | 161472 | 4696 | 29786304 |
Lumbar radiculopathy | 10.70 | 10.22 | 18 | 161460 | 865 | 29790135 |
Decreased interest | 10.69 | 10.22 | 31 | 161447 | 2164 | 29788836 |
Tongue movement disturbance | 10.66 | 10.22 | 6 | 161472 | 68 | 29790932 |
Multiple cardiac defects | 10.66 | 10.22 | 6 | 161472 | 68 | 29790932 |
Carcinogenicity | 10.66 | 10.22 | 6 | 161472 | 68 | 29790932 |
Autonomic nervous system imbalance | 10.66 | 10.22 | 33 | 161445 | 2388 | 29788612 |
Lipodystrophy acquired | 10.63 | 10.22 | 3 | 161475 | 3557 | 29787443 |
Joint injury | 10.63 | 10.22 | 67 | 161411 | 6610 | 29784390 |
Premature baby | 10.61 | 10.22 | 50 | 161428 | 16641 | 29774359 |
Disturbance in attention | 10.60 | 10.22 | 173 | 161305 | 21956 | 29769044 |
Osteonecrosis of jaw | 10.57 | 10.22 | 58 | 161420 | 18560 | 29772440 |
Rib fracture | 10.56 | 10.22 | 110 | 161368 | 12610 | 29778390 |
Developmental hip dysplasia | 10.54 | 10.22 | 10 | 161468 | 266 | 29790734 |
Incision site complication | 10.49 | 10.22 | 11 | 161467 | 331 | 29790669 |
Ventricular septal defect | 10.49 | 10.22 | 3 | 161475 | 3526 | 29787474 |
Aphasia | 10.47 | 10.22 | 155 | 161323 | 19284 | 29771716 |
Haematochezia | 10.46 | 10.22 | 126 | 161352 | 34096 | 29756904 |
Immunodeficiency common variable | 10.38 | 10.22 | 8 | 161470 | 159 | 29790841 |
Myelomalacia | 10.37 | 10.22 | 5 | 161473 | 40 | 29790960 |
Intervertebral disc injury | 10.37 | 10.22 | 4 | 161474 | 17 | 29790983 |
Road traffic accident | 10.35 | 10.22 | 139 | 161339 | 16932 | 29774068 |
White blood cell count increased | 10.33 | 10.22 | 151 | 161327 | 39522 | 29751478 |
Cardio-respiratory arrest | 10.30 | 10.22 | 392 | 161086 | 56914 | 29734086 |
Arthrofibrosis | 10.30 | 10.22 | 6 | 161472 | 73 | 29790927 |
Bipolar disorder | 10.27 | 10.22 | 44 | 161434 | 3732 | 29787268 |
Dysstasia | 10.27 | 10.22 | 94 | 161384 | 10411 | 29780589 |
Source | Code | Description |
---|---|---|
ATC | N03AX12 | NERVOUS SYSTEM ANTIEPILEPTICS ANTIEPILEPTICS Other antiepileptics |
FDA PE | N0000008486 | Decreased Central Nervous System Disorganized Electrical Activity |
FDA EPC | N0000175753 | Anti-epileptic Agent |
MeSH PA | D000700 | Analgesics |
MeSH PA | D014151 | Anti-Anxiety Agents |
MeSH PA | D000927 | Anticonvulsants |
MeSH PA | D018692 | Antimanic Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D018691 | Excitatory Amino Acid Antagonists |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D011619 | Psychotropic Drugs |
MeSH PA | D018689 | Sensory System Agents |
MeSH PA | D014149 | Tranquilizing Agents |
CHEBI has role | CHEBI:35623 | antiepileptic |
CHEBI has role | CHEBI:35703 | xenobiotic |
CHEBI has role | CHEBI:38215 | calcium channel blockers |
CHEBI has role | CHEBI:78298 | environmental contaminants |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Postherpetic neuralgia | indication | 2177002 | |
Restless legs | indication | 32914008 | DOID:0050425 |
Partial Epilepsy Treatment Adjunct | indication | ||
Alcohol use disorder | off-label use | 7200002 | |
Menopausal night sweats | off-label use | 42984000 | |
Chronic cough | off-label use | 68154008 | |
Chronic pain | off-label use | 82423001 | |
Insomnia | off-label use | 193462001 | |
Anxiety disorder | off-label use | 197480006 | DOID:2030 |
Menopausal flushing | off-label use | 198436008 | |
Fibromyalgia | off-label use | 203082005 | DOID:631 |
Neuropathic pain | off-label use | 247398009 | |
Chronic pruritus | off-label use | 418363000 | |
Refractory pruritis | off-label use | 418363000 | |
Post-stroke nausea | off-label use | 422587007 | |
Essential tremor | off-label use | 609558009 | DOID:4990 |
Intractable hiccups | off-label use | 716771000 | |
Acute postoperative pain | off-label use | 107401000119105 | |
Suicidal thoughts | contraindication | 6471006 | |
Depressive disorder | contraindication | 35489007 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.02 | acidic |
pKa2 | 10.31 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Voltage-dependent calcium channel subunit alpha-2/delta-1 | Ion channel | MODULATOR | IC50 | 7.26 | WOMBAT-PK | CHEMBL | |||
Voltage-dependent calcium channel subunit alpha-2/delta-2 | Ion channel | MODULATOR | IC50 | 6.93 | SCIENTIFIC LITERATURE | SCIENTIFIC LITERATURE | |||
Large neutral amino acids transporter small subunit 1 | Transporter | IC50 | 4.52 | WOMBAT-PK | |||||
Glutamate receptor ionotropic, NMDA 3A | Ion channel | WOMBAT-PK | |||||||
Gamma-aminobutyric acid type B receptor subunit 2 | GPCR | WOMBAT-PK | |||||||
Adenosine receptor A1 | GPCR | WOMBAT-PK | |||||||
Alpha-2A adrenergic receptor | GPCR | WOMBAT-PK | |||||||
Sodium channel protein type 5 subunit alpha | Ion channel | WOMBAT-PK | |||||||
Voltage-dependent calcium channel subunit alpha-2/delta-1 | Ion channel | Ki | 6.92 | CHEMBL | |||||
Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit | Ion channel | IC50 | 7.15 | CHEMBL |
ID | Source |
---|---|
4020833 | VUID |
N0000148345 | NUI |
D00332 | KEGG_DRUG |
4020833 | VANDF |
C0060926 | UMLSCUI |
CHEBI:42797 | CHEBI |
GBN | PDB_CHEM_ID |
CHEMBL940 | ChEMBL_ID |
DB00996 | DRUGBANK_ID |
D000077206 | MESH_DESCRIPTOR_UI |
5483 | IUPHAR_LIGAND_ID |
5094 | INN_ID |
6CW7F3G59X | UNII |
3446 | PUBCHEM_CID |
196498 | RXNORM |
2269 | MMSL |
4770 | MMSL |
60712 | MMSL |
d03182 | MMSL |
004415 | NDDF |
108402001 | SNOMEDCT_US |
386845007 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0401 | TABLET, FILM COATED | 800 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0513 | TABLET, FILM COATED | 600 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0803 | CAPSULE | 100 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0805 | CAPSULE | 300 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0806 | CAPSULE | 400 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-2012 | SOLUTION | 250 mg | ORAL | NDA | 31 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0228-2636 | TABLET, FILM COATED | 600 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0228-2637 | TABLET, FILM COATED | 800 mg | ORAL | ANDA | 26 sections |
GABAPENTIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0440-5562 | TABLET, FILM COATED | 600 mg | ORAL | ANDA | 24 sections |
GABAPENTIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0440-5563 | TABLET, FILM COATED | 800 mg | ORAL | ANDA | 24 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0440-7559 | CAPSULE | 300 mg | ORAL | ANDA | 14 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8132 | TABLET | 800 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8230 | CAPSULE | 100 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8231 | CAPSULE | 300 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8232 | CAPSULE | 400 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8233 | TABLET | 600 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8340 | CAPSULE | 100 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8341 | CAPSULE | 300 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8342 | CAPSULE | 400 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6586 | TABLET, FILM COATED | 800 mg | ORAL | ANDA | 25 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6665 | CAPSULE | 100 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6666 | CAPSULE | 300 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6667 | CAPSULE | 400 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6823 | TABLET, FILM COATED | 600 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7108 | TABLET, FILM COATED | 800 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10135-644 | CAPSULE | 100 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10135-645 | CAPSULE | 300 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10135-646 | CAPSULE | 400 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10135-647 | TABLET | 600 mg | ORAL | ANDA | 30 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10135-648 | TABLET | 800 mg | ORAL | ANDA | 30 sections |