Stem definition | Drug id | CAS RN |
---|---|---|
gabamimetic agents | 1264 | 60142-96-3 |
Dose | Unit | Route |
---|---|---|
1.80 | g | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 10 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 100 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 116.79 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 60 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.71 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 1.70 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.97 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 5.30 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 30, 1993 | FDA | PFIZER PHARMS |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 1642.83 | 9.81 | 4502 | 337284 | 270703 | 55679578 |
Drug ineffective for unapproved indication | 1048.60 | 9.81 | 1018 | 340768 | 24675 | 55925606 |
Pemphigus | 904.87 | 9.81 | 9 | 341777 | 157203 | 55793078 |
Completed suicide | 863.30 | 9.81 | 2256 | 339530 | 131577 | 55818704 |
Systemic lupus erythematosus | 671.08 | 9.81 | 138 | 341648 | 179940 | 55770341 |
Hand deformity | 647.88 | 9.81 | 43 | 341743 | 134449 | 55815832 |
Glossodynia | 641.14 | 9.81 | 84 | 341702 | 152374 | 55797907 |
Anti-cyclic citrullinated peptide antibody positive | 580.30 | 9.81 | 3 | 341783 | 98597 | 55851684 |
Rheumatoid arthritis | 571.65 | 9.81 | 901 | 340885 | 381703 | 55568578 |
Contraindicated product administered | 565.35 | 9.81 | 212 | 341574 | 186074 | 55764207 |
Pericarditis | 542.25 | 9.81 | 29 | 341757 | 108894 | 55841387 |
Synovitis | 521.50 | 9.81 | 165 | 341621 | 161140 | 55789141 |
Maternal exposure during pregnancy | 512.78 | 9.81 | 255 | 341531 | 189298 | 55760983 |
Multiple sclerosis relapse | 427.87 | 9.81 | 883 | 340903 | 44020 | 55906261 |
Arthropathy | 408.01 | 9.81 | 369 | 341417 | 199906 | 55750375 |
Duodenal ulcer perforation | 388.10 | 9.81 | 5 | 341781 | 68337 | 55881944 |
Rheumatoid factor positive | 364.91 | 9.81 | 12 | 341774 | 69048 | 55881233 |
Infusion related reaction | 352.13 | 9.81 | 451 | 341335 | 208480 | 55741801 |
Helicobacter infection | 351.05 | 9.81 | 24 | 341762 | 73244 | 55877037 |
Wound | 349.98 | 9.81 | 204 | 341582 | 138600 | 55811681 |
Somnolence | 340.31 | 9.81 | 1919 | 339867 | 161494 | 55788787 |
Toxicity to various agents | 316.99 | 9.81 | 2391 | 339395 | 222173 | 55728108 |
Fall | 316.01 | 9.81 | 3438 | 338348 | 354072 | 55596209 |
Joint swelling | 312.48 | 9.81 | 823 | 340963 | 288977 | 55661304 |
Hepatic enzyme increased | 311.02 | 9.81 | 349 | 341437 | 171035 | 55779246 |
Drug abuse | 309.45 | 9.81 | 1009 | 340777 | 66601 | 55883680 |
Discomfort | 288.81 | 9.81 | 261 | 341525 | 141500 | 55808781 |
Neuropathy peripheral | 267.83 | 9.81 | 1286 | 340500 | 101607 | 55848674 |
Abdominal discomfort | 266.89 | 9.81 | 831 | 340955 | 276443 | 55673838 |
Muscle injury | 261.14 | 9.81 | 14 | 341772 | 52486 | 55897795 |
Myoclonus | 255.83 | 9.81 | 384 | 341402 | 14819 | 55935462 |
Depression | 250.76 | 9.81 | 1912 | 339874 | 178205 | 55772076 |
Folliculitis | 241.59 | 9.81 | 26 | 341760 | 54953 | 55895328 |
General physical health deterioration | 234.21 | 9.81 | 421 | 341365 | 169589 | 55780692 |
Neuralgia | 224.53 | 9.81 | 465 | 341321 | 23230 | 55927051 |
Alopecia | 217.46 | 9.81 | 979 | 340807 | 292479 | 55657802 |
Feeling abnormal | 211.61 | 9.81 | 1463 | 340323 | 132139 | 55818142 |
Tremor | 210.45 | 9.81 | 1357 | 340429 | 119732 | 55830549 |
Therapeutic product effect decreased | 206.39 | 9.81 | 451 | 341335 | 169001 | 55781280 |
Swelling | 205.14 | 9.81 | 756 | 341030 | 239015 | 55711266 |
Sleep disorder due to general medical condition, insomnia type | 202.42 | 9.81 | 16 | 341770 | 43322 | 55906959 |
Suicidal ideation | 198.63 | 9.81 | 785 | 341001 | 56957 | 55893324 |
Treatment failure | 197.38 | 9.81 | 466 | 341320 | 169926 | 55780355 |
Hypersensitivity | 196.22 | 9.81 | 845 | 340941 | 255563 | 55694718 |
Dizziness | 194.46 | 9.81 | 3285 | 338501 | 372855 | 55577426 |
Multiple sclerosis | 193.72 | 9.81 | 483 | 341303 | 27319 | 55922962 |
Exposure during pregnancy | 190.11 | 9.81 | 335 | 341451 | 136007 | 55814274 |
Memory impairment | 186.29 | 9.81 | 1026 | 340760 | 85531 | 55864750 |
Product dose omission issue | 178.10 | 9.81 | 1964 | 339822 | 202789 | 55747492 |
Lower respiratory tract infection | 159.17 | 9.81 | 283 | 341503 | 114511 | 55835770 |
Hallucination | 155.39 | 9.81 | 651 | 341135 | 48498 | 55901783 |
Accidental death | 153.20 | 9.81 | 110 | 341676 | 1722 | 55948559 |
Muscle spasms | 152.41 | 9.81 | 1386 | 340400 | 135985 | 55814296 |
Balance disorder | 148.87 | 9.81 | 883 | 340903 | 75637 | 55874644 |
Irritable bowel syndrome | 146.70 | 9.81 | 120 | 341666 | 68338 | 55881943 |
Febrile neutropenia | 142.92 | 9.81 | 264 | 341522 | 105281 | 55845000 |
Anxiety | 139.75 | 9.81 | 1789 | 339997 | 191383 | 55758898 |
Vision blurred | 139.45 | 9.81 | 922 | 340864 | 82021 | 55868260 |
Impaired healing | 138.46 | 9.81 | 195 | 341591 | 86646 | 55863635 |
Liver injury | 138.37 | 9.81 | 41 | 341745 | 41807 | 55908474 |
Respiratory arrest | 135.53 | 9.81 | 452 | 341334 | 30173 | 55920108 |
Product use issue | 134.45 | 9.81 | 626 | 341160 | 185415 | 55764866 |
Drug intolerance | 133.03 | 9.81 | 1001 | 340785 | 263817 | 55686464 |
Withdrawal syndrome | 132.05 | 9.81 | 324 | 341462 | 18138 | 55932143 |
Swollen joint count increased | 128.46 | 9.81 | 4 | 341782 | 24180 | 55926101 |
Drug withdrawal syndrome | 127.46 | 9.81 | 396 | 341390 | 25461 | 55924820 |
Hypoaesthesia | 127.44 | 9.81 | 1367 | 340419 | 140124 | 55810157 |
Mental status changes | 126.67 | 9.81 | 507 | 341279 | 36994 | 55913287 |
Product complaint | 124.83 | 9.81 | 242 | 341544 | 11518 | 55938763 |
Pyrexia | 120.32 | 9.81 | 1804 | 339982 | 416969 | 55533312 |
C-reactive protein increased | 120.23 | 9.81 | 182 | 341604 | 78502 | 55871779 |
Rheumatic fever | 118.43 | 9.81 | 17 | 341769 | 28810 | 55921471 |
Blister | 116.52 | 9.81 | 310 | 341476 | 108577 | 55841704 |
Migraine | 115.39 | 9.81 | 912 | 340874 | 85885 | 55864396 |
C-reactive protein abnormal | 114.72 | 9.81 | 40 | 341746 | 36769 | 55913512 |
Drug dependence | 112.84 | 9.81 | 347 | 341439 | 22186 | 55928095 |
Seizure | 110.88 | 9.81 | 1205 | 340581 | 123914 | 55826367 |
Rash | 110.17 | 9.81 | 2222 | 339564 | 490825 | 55459456 |
Gait disturbance | 106.66 | 9.81 | 1485 | 340301 | 161836 | 55788445 |
Pain in extremity | 102.00 | 9.81 | 2444 | 339342 | 294987 | 55655294 |
Paraesthesia | 99.56 | 9.81 | 1221 | 340565 | 129293 | 55820988 |
Device expulsion | 95.05 | 9.81 | 33 | 341753 | 30416 | 55919865 |
Cardio-respiratory arrest | 94.80 | 9.81 | 618 | 341168 | 54703 | 55895578 |
Respiratory depression | 92.97 | 9.81 | 222 | 341564 | 12213 | 55938068 |
Ill-defined disorder | 90.52 | 9.81 | 174 | 341612 | 68369 | 55881912 |
Dyskinesia | 90.01 | 9.81 | 383 | 341403 | 28725 | 55921556 |
Unresponsive to stimuli | 89.41 | 9.81 | 406 | 341380 | 31319 | 55918962 |
Interstitial lung disease | 84.29 | 9.81 | 135 | 341651 | 56928 | 55893353 |
Live birth | 84.28 | 9.81 | 10 | 341776 | 19595 | 55930686 |
Sopor | 84.02 | 9.81 | 299 | 341487 | 20623 | 55929658 |
Infection | 77.42 | 9.81 | 809 | 340977 | 199397 | 55750884 |
Amnesia | 77.26 | 9.81 | 514 | 341272 | 45808 | 55904473 |
Lethargy | 75.91 | 9.81 | 554 | 341232 | 50887 | 55899394 |
Trigeminal neuralgia | 73.58 | 9.81 | 97 | 341689 | 3310 | 55946971 |
Urinary tract infection | 71.40 | 9.81 | 1939 | 339847 | 238574 | 55711707 |
Mental disorder | 70.99 | 9.81 | 308 | 341478 | 23296 | 55926985 |
Stiff person syndrome | 70.84 | 9.81 | 37 | 341749 | 313 | 55949968 |
Speech disorder | 70.55 | 9.81 | 429 | 341357 | 37064 | 55913217 |
Thrombocytopenia | 69.21 | 9.81 | 513 | 341273 | 135711 | 55814570 |
Off label use | 68.92 | 9.81 | 2721 | 339065 | 553459 | 55396822 |
Drug use disorder | 68.87 | 9.81 | 111 | 341675 | 4558 | 55945723 |
Burning sensation | 67.64 | 9.81 | 517 | 341269 | 48179 | 55902102 |
Muscular weakness | 67.43 | 9.81 | 948 | 340838 | 103504 | 55846777 |
Head injury | 64.92 | 9.81 | 313 | 341473 | 24753 | 55925528 |
Hepatic function abnormal | 64.11 | 9.81 | 69 | 341717 | 34489 | 55915792 |
Cytomegalovirus infection | 63.61 | 9.81 | 19 | 341767 | 19277 | 55931004 |
Back pain | 61.54 | 9.81 | 1880 | 339906 | 235290 | 55714991 |
Sleep apnoea syndrome | 60.15 | 9.81 | 315 | 341471 | 25746 | 55924535 |
Coordination abnormal | 60.09 | 9.81 | 191 | 341595 | 12430 | 55937851 |
Therapeutic response unexpected | 59.62 | 9.81 | 233 | 341553 | 16811 | 55933470 |
Sedation | 59.48 | 9.81 | 389 | 341397 | 34465 | 55915816 |
Bone erosion | 58.85 | 9.81 | 10 | 341776 | 14964 | 55935317 |
Insomnia | 58.40 | 9.81 | 1552 | 340234 | 190308 | 55759973 |
Cardiac arrest | 58.40 | 9.81 | 790 | 340996 | 85524 | 55864757 |
Hip arthroplasty | 58.35 | 9.81 | 90 | 341696 | 38533 | 55911748 |
Stomatitis | 58.05 | 9.81 | 462 | 341324 | 120348 | 55829933 |
Premature baby | 57.93 | 9.81 | 22 | 341764 | 19183 | 55931098 |
Full blood count decreased | 57.93 | 9.81 | 288 | 341498 | 23061 | 55927220 |
Hypersomnia | 57.65 | 9.81 | 224 | 341562 | 16117 | 55934164 |
Muscle twitching | 56.78 | 9.81 | 222 | 341564 | 16020 | 55934261 |
Influenza like illness | 56.14 | 9.81 | 592 | 341194 | 60396 | 55889885 |
Myelosuppression | 56.08 | 9.81 | 18 | 341768 | 17437 | 55932844 |
Inadequate analgesia | 56.08 | 9.81 | 75 | 341711 | 2596 | 55947685 |
Crying | 55.73 | 9.81 | 268 | 341518 | 21172 | 55929109 |
Intervertebral disc protrusion | 55.54 | 9.81 | 270 | 341516 | 21424 | 55928857 |
Cardiac failure | 54.76 | 9.81 | 284 | 341502 | 81809 | 55868472 |
Anaemia | 54.76 | 9.81 | 1222 | 340564 | 266289 | 55683992 |
Intentional product misuse | 54.20 | 9.81 | 514 | 341272 | 50990 | 55899291 |
Foetal exposure during pregnancy | 53.84 | 9.81 | 76 | 341710 | 33747 | 55916534 |
Restless legs syndrome | 53.17 | 9.81 | 224 | 341562 | 16723 | 55933558 |
Mucosal inflammation | 52.83 | 9.81 | 113 | 341673 | 42697 | 55907584 |
Confusional state | 52.65 | 9.81 | 1645 | 340141 | 206510 | 55743771 |
Rheumatoid nodule | 52.03 | 9.81 | 13 | 341773 | 14844 | 55935437 |
Intentional product use issue | 51.89 | 9.81 | 373 | 341413 | 99360 | 55850921 |
Malignant neoplasm progression | 51.69 | 9.81 | 250 | 341536 | 73337 | 55876944 |
Feeling drunk | 51.69 | 9.81 | 87 | 341699 | 3705 | 55946576 |
Multiple organ dysfunction syndrome | 51.45 | 9.81 | 157 | 341629 | 52613 | 55897668 |
Neck pain | 51.37 | 9.81 | 586 | 341200 | 60969 | 55889312 |
Sinusitis | 51.26 | 9.81 | 867 | 340919 | 196714 | 55753567 |
Knee arthroplasty | 51.21 | 9.81 | 121 | 341665 | 44138 | 55906143 |
Pancytopenia | 51.04 | 9.81 | 322 | 341464 | 88393 | 55861888 |
Drug ineffective | 49.75 | 9.81 | 4857 | 336929 | 914132 | 55036149 |
Overdose | 49.68 | 9.81 | 911 | 340875 | 104919 | 55845362 |
Nervousness | 49.61 | 9.81 | 324 | 341462 | 28691 | 55921590 |
Arthralgia | 49.26 | 9.81 | 2517 | 339269 | 499152 | 55451129 |
Euphoric mood | 49.11 | 9.81 | 92 | 341694 | 4266 | 55946015 |
Hallucination, visual | 48.81 | 9.81 | 223 | 341563 | 17245 | 55933036 |
Spinal operation | 48.32 | 9.81 | 125 | 341661 | 7231 | 55943050 |
Presbyacusis | 48.19 | 9.81 | 72 | 341714 | 2766 | 55947515 |
Hyperhidrosis | 48.11 | 9.81 | 821 | 340965 | 93267 | 55857014 |
Vertigo | 48.03 | 9.81 | 525 | 341261 | 54047 | 55896234 |
Pleural fibrosis | 48 | 9.81 | 80 | 341706 | 3379 | 55946902 |
Red blood cell sedimentation rate abnormal | 47.65 | 9.81 | 27 | 341759 | 18646 | 55931635 |
Nasopharyngitis | 47.32 | 9.81 | 1002 | 340784 | 219957 | 55730324 |
Urinary incontinence | 46.77 | 9.81 | 324 | 341462 | 29261 | 55921020 |
Back disorder | 46.29 | 9.81 | 151 | 341635 | 9962 | 55940319 |
Pleural thickening | 46.12 | 9.81 | 69 | 341717 | 2654 | 55947627 |
Premature delivery | 45.92 | 9.81 | 58 | 341728 | 27002 | 55923279 |
Anticipatory anxiety | 45.74 | 9.81 | 43 | 341743 | 999 | 55949282 |
Poisoning | 45.50 | 9.81 | 176 | 341610 | 12637 | 55937644 |
Blood magnesium increased | 44.68 | 9.81 | 71 | 341715 | 2880 | 55947401 |
Myocardial stunning | 44.64 | 9.81 | 21 | 341765 | 138 | 55950143 |
Blood cholesterol increased | 44.60 | 9.81 | 258 | 341528 | 72321 | 55877960 |
Therapeutic response decreased | 44.59 | 9.81 | 167 | 341619 | 52591 | 55897690 |
Gastrointestinal disorder | 44.51 | 9.81 | 453 | 341333 | 112249 | 55838032 |
Pregnancy | 44.35 | 9.81 | 83 | 341703 | 32950 | 55917331 |
Hepatotoxicity | 42.97 | 9.81 | 77 | 341709 | 31076 | 55919205 |
Diplopia | 42.81 | 9.81 | 240 | 341546 | 20129 | 55930152 |
Bone marrow failure | 42.64 | 9.81 | 66 | 341720 | 28220 | 55922061 |
Asthenia | 42.38 | 9.81 | 2515 | 339271 | 340458 | 55609823 |
Impaired driving ability | 41.91 | 9.81 | 83 | 341703 | 4013 | 55946268 |
Drug-induced liver injury | 41.67 | 9.81 | 92 | 341694 | 34370 | 55915911 |
Hyperaesthesia | 41.20 | 9.81 | 131 | 341655 | 8526 | 55941755 |
Ataxia | 41.08 | 9.81 | 185 | 341601 | 14218 | 55936063 |
Drug tolerance decreased | 41.06 | 9.81 | 15 | 341771 | 13396 | 55936885 |
Pleural effusion | 41 | 9.81 | 327 | 341459 | 85153 | 55865128 |
Drug resistance | 40.40 | 9.81 | 39 | 341747 | 20503 | 55929778 |
Surgery | 40.25 | 9.81 | 336 | 341450 | 32150 | 55918131 |
Mood altered | 39.95 | 9.81 | 174 | 341612 | 13181 | 55937100 |
Psoriatic arthropathy | 39.86 | 9.81 | 274 | 341512 | 73734 | 55876547 |
Death | 39.82 | 9.81 | 2491 | 339295 | 338935 | 55611346 |
Ankle fracture | 39.75 | 9.81 | 201 | 341585 | 16202 | 55934079 |
Diabetic neuropathy | 39.62 | 9.81 | 77 | 341709 | 3671 | 55946610 |
Macular degeneration | 39.44 | 9.81 | 34 | 341752 | 18874 | 55931407 |
Hypermobility syndrome | 39.24 | 9.81 | 35 | 341751 | 758 | 55949523 |
Nausea | 39.15 | 9.81 | 5251 | 336535 | 758927 | 55191354 |
Neutropenia | 38.78 | 9.81 | 701 | 341085 | 157466 | 55792815 |
Anger | 37.97 | 9.81 | 156 | 341630 | 11516 | 55938765 |
Hypokalaemia | 37.94 | 9.81 | 378 | 341408 | 94059 | 55856222 |
Dry mouth | 37.58 | 9.81 | 573 | 341213 | 63632 | 55886649 |
Pre-existing condition improved | 37.10 | 9.81 | 114 | 341672 | 7284 | 55942997 |
Therapy non-responder | 36.69 | 9.81 | 220 | 341566 | 61135 | 55889146 |
Anaphylactic shock | 36.47 | 9.81 | 47 | 341739 | 21693 | 55928588 |
Lupus-like syndrome | 36.23 | 9.81 | 15 | 341771 | 12412 | 55937869 |
Leukopenia | 36.08 | 9.81 | 267 | 341519 | 70673 | 55879608 |
Limb injury | 35.86 | 9.81 | 245 | 341541 | 22025 | 55928256 |
Eosinophilic colitis | 35.31 | 9.81 | 18 | 341768 | 144 | 55950137 |
Mental impairment | 35.24 | 9.81 | 162 | 341624 | 12560 | 55937721 |
Premature labour | 35.19 | 9.81 | 14 | 341772 | 11868 | 55938413 |
Accidental poisoning | 35.08 | 9.81 | 30 | 341756 | 613 | 55949668 |
Irritability | 35.06 | 9.81 | 303 | 341483 | 29285 | 55920996 |
Concussion | 34.97 | 9.81 | 120 | 341666 | 8126 | 55942155 |
Epigastric discomfort | 34.87 | 9.81 | 100 | 341686 | 6148 | 55944133 |
Disturbance in attention | 34.86 | 9.81 | 326 | 341460 | 32214 | 55918067 |
Type 2 diabetes mellitus | 34.80 | 9.81 | 156 | 341630 | 46706 | 55903575 |
Blood lactate dehydrogenase increased | 34.38 | 9.81 | 45 | 341741 | 20630 | 55929651 |
Drug screen positive | 34.01 | 9.81 | 69 | 341717 | 3395 | 55946886 |
Atrial fibrillation | 33.99 | 9.81 | 461 | 341325 | 108436 | 55841845 |
Somatic symptom disorder | 33.94 | 9.81 | 52 | 341734 | 2043 | 55948238 |
Brain injury | 33.82 | 9.81 | 100 | 341686 | 6255 | 55944026 |
Nerve injury | 33.58 | 9.81 | 125 | 341661 | 8812 | 55941469 |
Complex regional pain syndrome | 33.42 | 9.81 | 52 | 341734 | 2071 | 55948210 |
Cyst | 33.40 | 9.81 | 160 | 341626 | 12618 | 55937663 |
Nightmare | 33.23 | 9.81 | 195 | 341591 | 16631 | 55933650 |
Bradyphrenia | 33.19 | 9.81 | 102 | 341684 | 6518 | 55943763 |
Agitation | 33.15 | 9.81 | 501 | 341285 | 55535 | 55894746 |
Congenital absence of vertebra | 32.91 | 9.81 | 12 | 341774 | 36 | 55950245 |
Serotonin syndrome | 32.83 | 9.81 | 274 | 341512 | 26216 | 55924065 |
Incoherent | 32.76 | 9.81 | 77 | 341709 | 4192 | 55946089 |
Breast cancer stage III | 32.47 | 9.81 | 3 | 341783 | 7160 | 55943121 |
Joint injury | 32.13 | 9.81 | 266 | 341520 | 25388 | 55924893 |
Deafness neurosensory | 32.07 | 9.81 | 81 | 341705 | 4617 | 55945664 |
Pneumocystis jirovecii pneumonia | 31.83 | 9.81 | 29 | 341757 | 15672 | 55934609 |
Nerve compression | 31.52 | 9.81 | 115 | 341671 | 8029 | 55942252 |
Dysarthria | 31.42 | 9.81 | 373 | 341413 | 39177 | 55911104 |
Hyperreflexia | 31.23 | 9.81 | 86 | 341700 | 5164 | 55945117 |
Suspected suicide | 31.01 | 9.81 | 88 | 341698 | 5378 | 55944903 |
Pulmonary fibrosis | 30.85 | 9.81 | 86 | 341700 | 29672 | 55920609 |
Visual impairment | 30.81 | 9.81 | 627 | 341159 | 73575 | 55876706 |
Panniculitis | 30.14 | 9.81 | 11 | 341775 | 9831 | 55940450 |
Intervertebral disc degeneration | 29.99 | 9.81 | 168 | 341618 | 14086 | 55936195 |
Osteonecrosis of jaw | 29.90 | 9.81 | 103 | 341683 | 33255 | 55917026 |
Paranoia | 29.90 | 9.81 | 137 | 341649 | 10607 | 55939674 |
Thrombotic microangiopathy | 29.71 | 9.81 | 10 | 341776 | 9401 | 55940880 |
Limb discomfort | 29.67 | 9.81 | 269 | 341517 | 26353 | 55923928 |
Drug reaction with eosinophilia and systemic symptoms | 29.65 | 9.81 | 90 | 341696 | 30214 | 55920067 |
Gait inability | 29.62 | 9.81 | 386 | 341400 | 41432 | 55908849 |
Depressed level of consciousness | 29.41 | 9.81 | 494 | 341292 | 55939 | 55894342 |
Neovascularisation | 29.32 | 9.81 | 34 | 341752 | 1015 | 55949266 |
Body height decreased | 29.28 | 9.81 | 122 | 341664 | 9063 | 55941218 |
Melaena | 29.15 | 9.81 | 82 | 341704 | 28208 | 55922073 |
Febrile bone marrow aplasia | 29.14 | 9.81 | 3 | 341783 | 6569 | 55943712 |
Rash maculo-papular | 28.90 | 9.81 | 85 | 341701 | 28822 | 55921459 |
Herpes zoster | 28.52 | 9.81 | 632 | 341154 | 75257 | 55875024 |
Peroneal nerve palsy | 28.48 | 9.81 | 75 | 341711 | 4386 | 55945895 |
Gestational diabetes | 28.35 | 9.81 | 7 | 341779 | 8057 | 55942224 |
Musculoskeletal stiffness | 28.19 | 9.81 | 726 | 341060 | 155281 | 55795000 |
Somatic delusion | 27.82 | 9.81 | 25 | 341761 | 547 | 55949734 |
Congenital thrombocytopenia | 27.78 | 9.81 | 11 | 341775 | 44 | 55950237 |
Focal dyscognitive seizures | 27.42 | 9.81 | 56 | 341730 | 2769 | 55947512 |
Pituitary tumour benign | 27.30 | 9.81 | 45 | 341741 | 1883 | 55948398 |
Septic shock | 27.23 | 9.81 | 237 | 341549 | 60598 | 55889683 |
Haemophagocytic lymphohistiocytosis | 27.19 | 9.81 | 12 | 341774 | 9560 | 55940721 |
Lymphoedema | 26.91 | 9.81 | 131 | 341655 | 10399 | 55939882 |
Coma | 26.76 | 9.81 | 510 | 341276 | 59145 | 55891136 |
Abortion spontaneous | 26.63 | 9.81 | 156 | 341630 | 43597 | 55906684 |
Muscle tightness | 26.41 | 9.81 | 133 | 341653 | 10703 | 55939578 |
Central nervous system lesion | 26.39 | 9.81 | 125 | 341661 | 9813 | 55940468 |
Thinking abnormal | 26.37 | 9.81 | 125 | 341661 | 9816 | 55940465 |
Neutropenic sepsis | 26.34 | 9.81 | 32 | 341754 | 15153 | 55935128 |
Dysstasia | 26.05 | 9.81 | 204 | 341582 | 19150 | 55931131 |
Asterixis | 25.64 | 9.81 | 34 | 341752 | 1167 | 55949114 |
Human epidermal growth factor receptor decreased | 25.62 | 9.81 | 8 | 341778 | 12 | 55950269 |
Bone cyst | 25.62 | 9.81 | 46 | 341740 | 2064 | 55948217 |
Encephalopathy | 25.41 | 9.81 | 327 | 341459 | 34998 | 55915283 |
Drug diversion | 25.36 | 9.81 | 28 | 341758 | 791 | 55949490 |
Therapy cessation | 25.24 | 9.81 | 265 | 341521 | 26999 | 55923282 |
Headache | 25.20 | 9.81 | 3814 | 337972 | 555230 | 55395051 |
Thrombosis | 24.95 | 9.81 | 503 | 341283 | 58924 | 55891357 |
Substance abuse | 24.84 | 9.81 | 72 | 341714 | 4453 | 55945828 |
Loss of consciousness | 24.48 | 9.81 | 852 | 340934 | 108497 | 55841784 |
Bipolar disorder | 24.41 | 9.81 | 101 | 341685 | 7479 | 55942802 |
Anorgasmia | 24.20 | 9.81 | 23 | 341763 | 542 | 55949739 |
Dysphemia | 24.15 | 9.81 | 49 | 341737 | 2411 | 55947870 |
Ascites | 23.85 | 9.81 | 132 | 341654 | 37412 | 55912869 |
Pulmonary toxicity | 23.83 | 9.81 | 9 | 341777 | 7874 | 55942407 |
Skin necrosis | 23.69 | 9.81 | 24 | 341762 | 12337 | 55937944 |
Erythema | 23.52 | 9.81 | 744 | 341042 | 155195 | 55795086 |
Hepatic failure | 23.37 | 9.81 | 114 | 341672 | 33372 | 55916909 |
Pollakiuria | 23.35 | 9.81 | 245 | 341541 | 24957 | 55925324 |
Bronchiectasis | 23.32 | 9.81 | 21 | 341765 | 11413 | 55938868 |
Injection site mass | 23.15 | 9.81 | 178 | 341608 | 16615 | 55933666 |
Agranulocytosis | 23.11 | 9.81 | 66 | 341720 | 22593 | 55927688 |
Disorientation | 23.09 | 9.81 | 331 | 341455 | 36282 | 55913999 |
Exposure via ingestion | 23.04 | 9.81 | 52 | 341734 | 2756 | 55947525 |
Blood parathyroid hormone decreased | 22.96 | 9.81 | 11 | 341775 | 8353 | 55941928 |
Foot fracture | 22.61 | 9.81 | 217 | 341569 | 21592 | 55928689 |
Hypercholesterolaemia | 22.56 | 9.81 | 33 | 341753 | 14440 | 55935841 |
Tooth loss | 22.46 | 9.81 | 87 | 341699 | 6250 | 55944031 |
Condition aggravated | 22.43 | 9.81 | 1796 | 339990 | 343102 | 55607179 |
Cervical spinal stenosis | 22.38 | 9.81 | 42 | 341744 | 1950 | 55948331 |
Pneumonia | 22.19 | 9.81 | 2809 | 338977 | 404289 | 55545992 |
Hyponatraemia | 22.18 | 9.81 | 462 | 341324 | 101677 | 55848604 |
Myoclonic epilepsy | 22.13 | 9.81 | 31 | 341755 | 1122 | 55949159 |
Bone density decreased | 22.02 | 9.81 | 27 | 341759 | 12733 | 55937548 |
Cognitive disorder | 21.68 | 9.81 | 419 | 341367 | 48714 | 55901567 |
Product use in unapproved indication | 21.60 | 9.81 | 1054 | 340732 | 139768 | 55810513 |
Somnambulism | 21.50 | 9.81 | 74 | 341712 | 5018 | 55945263 |
Myelodysplastic syndrome | 21.35 | 9.81 | 42 | 341744 | 16364 | 55933917 |
Pruritus | 21.33 | 9.81 | 1644 | 340142 | 314979 | 55635302 |
Tardive dyskinesia | 21.31 | 9.81 | 101 | 341685 | 7930 | 55942351 |
Progressive multiple sclerosis | 21.30 | 9.81 | 25 | 341761 | 756 | 55949525 |
Psychotic disorder due to a general medical condition | 21.26 | 9.81 | 15 | 341771 | 228 | 55950053 |
Skin reaction | 21.14 | 9.81 | 29 | 341757 | 13034 | 55937247 |
Bradycardia | 20.97 | 9.81 | 286 | 341500 | 67218 | 55883063 |
Oesophageal spasm | 20.92 | 9.81 | 50 | 341736 | 2752 | 55947529 |
Acute myeloid leukaemia | 20.77 | 9.81 | 45 | 341741 | 16927 | 55933354 |
Colitis ulcerative | 20.74 | 9.81 | 77 | 341709 | 24314 | 55925967 |
Secondary progressive multiple sclerosis | 20.71 | 9.81 | 33 | 341753 | 1342 | 55948939 |
Hypokinesia | 20.70 | 9.81 | 141 | 341645 | 12662 | 55937619 |
Device use error | 20.67 | 9.81 | 4 | 341782 | 5452 | 55944829 |
Transaminases increased | 20.63 | 9.81 | 97 | 341689 | 28673 | 55921608 |
Drug titration error | 20.52 | 9.81 | 23 | 341763 | 661 | 55949620 |
Panic attack | 20.49 | 9.81 | 202 | 341584 | 20245 | 55930036 |
Dislocation of vertebra | 20.45 | 9.81 | 4 | 341782 | 5411 | 55944870 |
Dysphagia | 20.25 | 9.81 | 646 | 341140 | 81301 | 55868980 |
Sacroiliitis | 20.20 | 9.81 | 49 | 341737 | 2723 | 55947558 |
Jaundice | 20.18 | 9.81 | 91 | 341695 | 27203 | 55923078 |
Autonomic nervous system imbalance | 20.15 | 9.81 | 47 | 341739 | 2546 | 55947735 |
Eosinophilia | 20.09 | 9.81 | 59 | 341727 | 20018 | 55930263 |
Unintentional medical device removal | 19.91 | 9.81 | 5 | 341781 | 5689 | 55944592 |
Therapy interrupted | 19.62 | 9.81 | 240 | 341546 | 25385 | 55924896 |
Micturition urgency | 19.48 | 9.81 | 105 | 341681 | 8676 | 55941605 |
Acute respiratory distress syndrome | 19.45 | 9.81 | 68 | 341718 | 21858 | 55928423 |
Transplant rejection | 19.37 | 9.81 | 19 | 341767 | 9915 | 55940366 |
Paradoxical drug reaction | 19.28 | 9.81 | 59 | 341727 | 3761 | 55946520 |
Hepatocellular injury | 19.24 | 9.81 | 89 | 341697 | 26425 | 55923856 |
Creatinine renal clearance decreased | 19.18 | 9.81 | 37 | 341749 | 14522 | 55935759 |
Metabolic encephalopathy | 19.13 | 9.81 | 73 | 341713 | 5207 | 55945074 |
Arteriovenous malformation | 19.09 | 9.81 | 31 | 341755 | 1281 | 55949000 |
Chronic obstructive pulmonary disease | 19.06 | 9.81 | 470 | 341316 | 56945 | 55893336 |
Prescription drug used without a prescription | 18.92 | 9.81 | 39 | 341747 | 1941 | 55948340 |
Cytomegalovirus viraemia | 18.89 | 9.81 | 4 | 341782 | 5116 | 55945165 |
Psychomotor hyperactivity | 18.87 | 9.81 | 113 | 341673 | 9707 | 55940574 |
Pulmonary aplasia | 18.84 | 9.81 | 6 | 341780 | 10 | 55950271 |
Foetal growth restriction | 18.49 | 9.81 | 10 | 341776 | 7089 | 55943192 |
Toxic epidermal necrolysis | 18.47 | 9.81 | 70 | 341716 | 21972 | 55928309 |
Metastases to liver | 18.45 | 9.81 | 68 | 341718 | 21518 | 55928763 |
Sensory disturbance | 18.45 | 9.81 | 135 | 341651 | 12408 | 55937873 |
Laboratory test abnormal | 18.35 | 9.81 | 230 | 341556 | 24465 | 55925816 |
Schizophrenia | 18.34 | 9.81 | 22 | 341764 | 10477 | 55939804 |
Fibromyalgia | 18.34 | 9.81 | 483 | 341303 | 59120 | 55891161 |
Tuberculosis | 18.34 | 9.81 | 24 | 341762 | 11005 | 55939276 |
Plasma cell myeloma | 18.33 | 9.81 | 391 | 341395 | 46255 | 55904026 |
Device difficult to use | 18.33 | 9.81 | 23 | 341763 | 10738 | 55939543 |
Cystitis | 18.30 | 9.81 | 408 | 341378 | 48630 | 55901651 |
Glycosylated haemoglobin decreased | 18.26 | 9.81 | 19 | 341767 | 501 | 55949780 |
Urticaria | 18.20 | 9.81 | 706 | 341080 | 143970 | 55806311 |
Facial pain | 18.14 | 9.81 | 95 | 341691 | 7763 | 55942518 |
Post herpetic neuralgia | 18.03 | 9.81 | 39 | 341747 | 2008 | 55948273 |
Visual snow syndrome | 17.87 | 9.81 | 7 | 341779 | 27 | 55950254 |
Rib deformity | 17.86 | 9.81 | 13 | 341773 | 208 | 55950073 |
Depressed mood | 17.76 | 9.81 | 315 | 341471 | 36044 | 55914237 |
Dental caries | 17.66 | 9.81 | 114 | 341672 | 10054 | 55940227 |
Hypertension | 17.61 | 9.81 | 1261 | 340525 | 243017 | 55707264 |
Spinal disorder | 17.60 | 9.81 | 103 | 341683 | 8775 | 55941506 |
Haematotoxicity | 17.57 | 9.81 | 15 | 341771 | 8368 | 55941913 |
Device adhesion issue | 17.56 | 9.81 | 3 | 341783 | 4471 | 55945810 |
Low birth weight baby | 17.53 | 9.81 | 8 | 341778 | 6250 | 55944031 |
Tinnitus | 17.53 | 9.81 | 268 | 341518 | 29774 | 55920507 |
Economic problem | 17.51 | 9.81 | 37 | 341749 | 1874 | 55948407 |
Disorganised speech | 17.49 | 9.81 | 27 | 341759 | 1068 | 55949213 |
Epistaxis | 17.38 | 9.81 | 294 | 341492 | 66729 | 55883552 |
Oesophageal obstruction | 17.35 | 9.81 | 18 | 341768 | 473 | 55949808 |
Foot deformity | 17.28 | 9.81 | 80 | 341706 | 23745 | 55926536 |
Maternal exposure before pregnancy | 17.22 | 9.81 | 10 | 341776 | 6813 | 55943468 |
Hot flush | 17.19 | 9.81 | 388 | 341398 | 46338 | 55903943 |
Drug abuser | 17.17 | 9.81 | 47 | 341739 | 2812 | 55947469 |
Accidental exposure to product | 17.15 | 9.81 | 84 | 341702 | 24563 | 55925718 |
Injury | 17.04 | 9.81 | 258 | 341528 | 59593 | 55890688 |
Graft versus host disease | 17.02 | 9.81 | 10 | 341776 | 6771 | 55943510 |
Constipation | 16.92 | 9.81 | 1435 | 340351 | 200508 | 55749773 |
Pre-eclampsia | 16.82 | 9.81 | 16 | 341770 | 8470 | 55941811 |
Atonic urinary bladder | 16.76 | 9.81 | 9 | 341777 | 81 | 55950200 |
Fatigue | 16.68 | 9.81 | 5190 | 336596 | 783362 | 55166919 |
JC polyomavirus test positive | 16.67 | 9.81 | 28 | 341758 | 1190 | 55949091 |
Urinary retention | 16.60 | 9.81 | 251 | 341535 | 27823 | 55922458 |
Blood pressure systolic abnormal | 16.54 | 9.81 | 21 | 341765 | 9756 | 55940525 |
Bladder disorder | 16.50 | 9.81 | 94 | 341692 | 7930 | 55942351 |
White blood cell count decreased | 16.49 | 9.81 | 929 | 340857 | 125061 | 55825220 |
Diffuse axonal injury | 16.48 | 9.81 | 9 | 341777 | 84 | 55950197 |
Facial spasm | 16.43 | 9.81 | 20 | 341766 | 629 | 55949652 |
Obstructive airways disorder | 16.43 | 9.81 | 52 | 341734 | 17230 | 55933051 |
Subdural hygroma | 16.39 | 9.81 | 13 | 341773 | 238 | 55950043 |
Cerebrovascular accident | 16.28 | 9.81 | 748 | 341038 | 98522 | 55851759 |
Hip fracture | 16.27 | 9.81 | 242 | 341544 | 26731 | 55923550 |
Anal incontinence | 16.20 | 9.81 | 129 | 341657 | 12169 | 55938112 |
Osteosclerosis | 16.14 | 9.81 | 54 | 341732 | 3609 | 55946672 |
Blood potassium decreased | 16.12 | 9.81 | 327 | 341459 | 38345 | 55911936 |
Generalised tonic-clonic seizure | 16.12 | 9.81 | 246 | 341540 | 27320 | 55922961 |
Blood potassium increased | 16.09 | 9.81 | 168 | 341618 | 17093 | 55933188 |
Cerebral infarction | 16.06 | 9.81 | 76 | 341710 | 22429 | 55927852 |
Head banging | 16.06 | 9.81 | 16 | 341770 | 400 | 55949881 |
Abortion induced | 16.03 | 9.81 | 21 | 341765 | 9624 | 55940657 |
Drug effective for unapproved indication | 16.02 | 9.81 | 43 | 341743 | 2543 | 55947738 |
Osteoporosis | 16.00 | 9.81 | 221 | 341565 | 51831 | 55898450 |
Posterior reversible encephalopathy syndrome | 15.90 | 9.81 | 47 | 341739 | 15913 | 55934368 |
Cholestasis | 15.83 | 9.81 | 97 | 341689 | 26816 | 55923465 |
Deprescribing error | 15.76 | 9.81 | 6 | 341780 | 21 | 55950260 |
Shock haemorrhagic | 15.71 | 9.81 | 19 | 341767 | 9014 | 55941267 |
Blood lactic acid | 15.63 | 9.81 | 9 | 341777 | 94 | 55950187 |
Cardiogenic shock | 15.60 | 9.81 | 49 | 341737 | 16276 | 55934005 |
Gastrointestinal motility disorder | 15.39 | 9.81 | 63 | 341723 | 4643 | 55945638 |
Red blood cell sedimentation rate increased | 15.37 | 9.81 | 145 | 341641 | 36478 | 55913803 |
Gastroschisis | 15.31 | 9.81 | 13 | 341773 | 263 | 55950018 |
Basal cell carcinoma | 15.30 | 9.81 | 90 | 341696 | 25131 | 55925150 |
Bronchitis | 15.26 | 9.81 | 831 | 340955 | 111480 | 55838801 |
Tubulointerstitial nephritis | 15.25 | 9.81 | 51 | 341735 | 16614 | 55933667 |
Breast cancer stage II | 15.16 | 9.81 | 8 | 341778 | 5750 | 55944531 |
Hostility | 15.13 | 9.81 | 34 | 341752 | 1797 | 55948484 |
Road traffic accident | 15.11 | 9.81 | 246 | 341540 | 27681 | 55922600 |
Spinal osteoarthritis | 15.08 | 9.81 | 147 | 341639 | 14689 | 55935592 |
Myocardial oedema | 15 | 9.81 | 9 | 341777 | 102 | 55950179 |
Accidental overdose | 14.96 | 9.81 | 190 | 341596 | 20271 | 55930010 |
Joint destruction | 14.90 | 9.81 | 6 | 341780 | 5049 | 55945232 |
Caesarean section | 14.89 | 9.81 | 49 | 341737 | 16042 | 55934239 |
Dry eye | 14.89 | 9.81 | 302 | 341484 | 35414 | 55914867 |
Epstein-Barr virus infection | 14.87 | 9.81 | 14 | 341772 | 7449 | 55942832 |
Pineal gland cyst | 14.80 | 9.81 | 5 | 341781 | 11 | 55950270 |
Carpal tunnel syndrome | 14.80 | 9.81 | 172 | 341614 | 17972 | 55932309 |
Genital haemorrhage | 14.73 | 9.81 | 12 | 341774 | 6850 | 55943431 |
Postmortem blood drug level increased | 14.59 | 9.81 | 18 | 341768 | 574 | 55949707 |
Tonic clonic movements | 14.55 | 9.81 | 27 | 341759 | 1243 | 55949038 |
Peritonitis | 14.54 | 9.81 | 50 | 341736 | 16152 | 55934129 |
Colitis | 14.53 | 9.81 | 173 | 341613 | 41638 | 55908643 |
Breast cancer stage I | 14.52 | 9.81 | 10 | 341776 | 6220 | 55944061 |
Ageusia | 14.48 | 9.81 | 127 | 341659 | 12324 | 55937957 |
Myotonia | 14.46 | 9.81 | 10 | 341776 | 147 | 55950134 |
Stillbirth | 14.45 | 9.81 | 10 | 341776 | 6204 | 55944077 |
Septic encephalopathy | 14.44 | 9.81 | 8 | 341778 | 77 | 55950204 |
Ventricular fibrillation | 14.28 | 9.81 | 28 | 341758 | 10924 | 55939357 |
Disseminated intravascular coagulation | 14.22 | 9.81 | 58 | 341728 | 17827 | 55932454 |
Postmortem blood drug level abnormal | 14.22 | 9.81 | 14 | 341772 | 345 | 55949936 |
Dysgraphia | 14.19 | 9.81 | 43 | 341743 | 2727 | 55947554 |
Rib fracture | 14.18 | 9.81 | 187 | 341599 | 20122 | 55930159 |
Spinal cord injury | 14.17 | 9.81 | 20 | 341766 | 729 | 55949552 |
Ejection fraction decreased | 14.16 | 9.81 | 67 | 341719 | 19774 | 55930507 |
Delirium | 14.10 | 9.81 | 348 | 341438 | 42169 | 55908112 |
Pancreatitis chronic | 14.07 | 9.81 | 38 | 341748 | 2256 | 55948025 |
Jaundice cholestatic | 14.05 | 9.81 | 8 | 341778 | 5511 | 55944770 |
Osteopenia | 13.93 | 9.81 | 170 | 341616 | 17971 | 55932310 |
Cellulitis | 13.90 | 9.81 | 572 | 341214 | 74377 | 55875904 |
Hypoxic-ischaemic encephalopathy | 13.85 | 9.81 | 54 | 341732 | 3891 | 55946390 |
Gastrointestinal haemorrhage | 13.83 | 9.81 | 353 | 341433 | 75598 | 55874683 |
Nervous system disorder | 13.73 | 9.81 | 160 | 341626 | 16729 | 55933552 |
Kidney infection | 13.72 | 9.81 | 189 | 341597 | 20536 | 55929745 |
Electroencephalogram abnormal | 13.72 | 9.81 | 50 | 341736 | 3489 | 55946792 |
Abnormal dreams | 13.71 | 9.81 | 103 | 341683 | 9546 | 55940735 |
Diarrhoea | 13.68 | 9.81 | 4205 | 337581 | 634302 | 55315979 |
Toxicologic test abnormal | 13.62 | 9.81 | 19 | 341767 | 685 | 55949596 |
Pharyngitis | 13.59 | 9.81 | 62 | 341724 | 18476 | 55931805 |
Adjustment disorder with depressed mood | 13.57 | 9.81 | 7 | 341779 | 5096 | 55945185 |
Juvenile idiopathic arthritis | 13.53 | 9.81 | 6 | 341780 | 4767 | 55945514 |
Hyperbilirubinaemia | 13.49 | 9.81 | 26 | 341760 | 10209 | 55940072 |
Oligohydramnios | 13.48 | 9.81 | 10 | 341776 | 5984 | 55944297 |
Illness | 13.47 | 9.81 | 289 | 341497 | 34222 | 55916059 |
Mucocutaneous haemorrhage | 13.46 | 9.81 | 8 | 341778 | 89 | 55950192 |
Sedation complication | 13.43 | 9.81 | 32 | 341754 | 11640 | 55938641 |
Injection site induration | 13.41 | 9.81 | 94 | 341692 | 8521 | 55941760 |
Snoring | 13.38 | 9.81 | 50 | 341736 | 3531 | 55946750 |
Wrong patient received product | 13.35 | 9.81 | 36 | 341750 | 2135 | 55948146 |
Hepatitis | 13.35 | 9.81 | 144 | 341642 | 35297 | 55914984 |
Proteinuria | 13.34 | 9.81 | 58 | 341728 | 17512 | 55932769 |
Wheezing | 13.31 | 9.81 | 350 | 341436 | 74676 | 55875605 |
Sleep talking | 13.27 | 9.81 | 22 | 341764 | 925 | 55949356 |
Phobia | 13.25 | 9.81 | 13 | 341773 | 319 | 55949962 |
Breakthrough pain | 13.17 | 9.81 | 25 | 341761 | 1171 | 55949110 |
Injection site atrophy | 13.15 | 9.81 | 16 | 341770 | 503 | 55949778 |
Substance use | 13.10 | 9.81 | 14 | 341772 | 381 | 55949900 |
Alanine aminotransferase abnormal | 12.92 | 9.81 | 5 | 341781 | 4310 | 55945971 |
Toxic skin eruption | 12.87 | 9.81 | 33 | 341753 | 11706 | 55938575 |
Hepatitis cholestatic | 12.82 | 9.81 | 12 | 341774 | 6402 | 55943879 |
Persistent depressive disorder | 12.81 | 9.81 | 21 | 341765 | 875 | 55949406 |
Drug screen false positive | 12.79 | 9.81 | 20 | 341766 | 800 | 55949481 |
Influenza | 12.77 | 9.81 | 704 | 341082 | 94557 | 55855724 |
Hyperprolactinaemia | 12.76 | 9.81 | 50 | 341736 | 3611 | 55946670 |
Adverse event | 12.76 | 9.81 | 248 | 341538 | 55128 | 55895153 |
Intentional self-injury | 12.73 | 9.81 | 218 | 341568 | 24774 | 55925507 |
Urinary hesitation | 12.70 | 9.81 | 34 | 341752 | 2008 | 55948273 |
Movement disorder | 12.68 | 9.81 | 175 | 341611 | 19023 | 55931258 |
Drug eruption | 12.60 | 9.81 | 98 | 341688 | 25665 | 55924616 |
Paralysis | 12.60 | 9.81 | 96 | 341690 | 8936 | 55941345 |
Lymphoma | 12.47 | 9.81 | 28 | 341758 | 10400 | 55939881 |
Oesophageal pain | 12.47 | 9.81 | 46 | 341740 | 3229 | 55947052 |
Haemolysis | 12.46 | 9.81 | 12 | 341774 | 6316 | 55943965 |
Neutrophil count decreased | 12.45 | 9.81 | 220 | 341566 | 49602 | 55900679 |
Prophylaxis | 12.44 | 9.81 | 4 | 341782 | 7 | 55950274 |
Cervicogenic headache | 12.44 | 9.81 | 4 | 341782 | 7 | 55950274 |
Heteroplasia | 12.44 | 9.81 | 4 | 341782 | 7 | 55950274 |
Stereotypy | 12.34 | 9.81 | 14 | 341772 | 408 | 55949873 |
Epidermal naevus | 12.33 | 9.81 | 3 | 341783 | 0 | 55950281 |
Glossopharyngeal neuralgia | 12.33 | 9.81 | 3 | 341783 | 0 | 55950281 |
Ligamentum flavum hypertrophy | 12.33 | 9.81 | 3 | 341783 | 0 | 55950281 |
Muscle relaxant drug level above therapeutic | 12.33 | 9.81 | 3 | 341783 | 0 | 55950281 |
CSF neutrophil count increased | 12.33 | 9.81 | 3 | 341783 | 0 | 55950281 |
Pharyngeal neoplasm | 12.33 | 9.81 | 3 | 341783 | 0 | 55950281 |
Turbinectomy | 12.33 | 9.81 | 3 | 341783 | 0 | 55950281 |
Aphasia | 12.29 | 9.81 | 256 | 341530 | 30159 | 55920122 |
Face oedema | 12.20 | 9.81 | 64 | 341722 | 18388 | 55931893 |
Skin toxicity | 12.13 | 9.81 | 5 | 341781 | 4148 | 55946133 |
Dyspnoea | 12.05 | 9.81 | 3309 | 338477 | 589268 | 55361013 |
Vascular malformation | 12.04 | 9.81 | 13 | 341773 | 358 | 55949923 |
Angioedema | 12.04 | 9.81 | 178 | 341608 | 41275 | 55909006 |
Paranasal cyst | 12.01 | 9.81 | 13 | 341773 | 359 | 55949922 |
Allodynia | 11.93 | 9.81 | 19 | 341767 | 772 | 55949509 |
Lung adenocarcinoma stage I | 11.91 | 9.81 | 5 | 341781 | 24 | 55950257 |
Gastric bypass | 11.89 | 9.81 | 28 | 341758 | 1526 | 55948755 |
Post procedural infection | 11.87 | 9.81 | 89 | 341697 | 8243 | 55942038 |
Vulvar basal cell carcinoma | 11.74 | 9.81 | 5 | 341781 | 25 | 55950256 |
Blood iron abnormal | 11.74 | 9.81 | 3 | 341783 | 3374 | 55946907 |
Internal hernia | 11.67 | 9.81 | 6 | 341780 | 49 | 55950232 |
Parapsoriasis | 11.66 | 9.81 | 8 | 341778 | 116 | 55950165 |
Haemangioma of skin | 11.64 | 9.81 | 12 | 341774 | 313 | 55949968 |
Hypopnoea | 11.64 | 9.81 | 37 | 341749 | 2408 | 55947873 |
Blood potassium abnormal | 11.63 | 9.81 | 36 | 341750 | 2309 | 55947972 |
Central nervous system infection | 11.60 | 9.81 | 18 | 341768 | 715 | 55949566 |
Narcolepsy | 11.60 | 9.81 | 25 | 341761 | 1284 | 55948997 |
Drug screen negative | 11.58 | 9.81 | 11 | 341775 | 259 | 55950022 |
Upper airway resistance syndrome | 11.49 | 9.81 | 4 | 341782 | 10 | 55950271 |
X-ray abnormal | 11.48 | 9.81 | 6 | 341780 | 4335 | 55945946 |
Radiculopathy | 11.41 | 9.81 | 66 | 341720 | 5599 | 55944682 |
Mobility decreased | 11.39 | 9.81 | 488 | 341298 | 98503 | 55851778 |
Sensory loss | 11.38 | 9.81 | 93 | 341693 | 8842 | 55941439 |
Naevus haemorrhage | 11.37 | 9.81 | 8 | 341778 | 121 | 55950160 |
Neuroma | 11.34 | 9.81 | 13 | 341773 | 383 | 55949898 |
Formication | 11.33 | 9.81 | 51 | 341735 | 3919 | 55946362 |
Seasonal allergy | 11.32 | 9.81 | 156 | 341630 | 16952 | 55933329 |
Femur fracture | 11.32 | 9.81 | 169 | 341617 | 39126 | 55911155 |
Tooth disorder | 11.30 | 9.81 | 218 | 341568 | 25335 | 55924946 |
Unevaluable event | 11.28 | 9.81 | 374 | 341412 | 47313 | 55902968 |
Urine amphetamine positive | 11.27 | 9.81 | 6 | 341780 | 53 | 55950228 |
Withdrawal catatonia | 11.27 | 9.81 | 6 | 341780 | 53 | 55950228 |
Enterocolitis | 11.27 | 9.81 | 16 | 341770 | 7088 | 55943193 |
Nerve block | 11.26 | 9.81 | 17 | 341769 | 659 | 55949622 |
Congenital neuropathy | 11.22 | 9.81 | 4 | 341782 | 11 | 55950270 |
Connective tissue inflammation | 11.17 | 9.81 | 6 | 341780 | 54 | 55950227 |
Liver function test increased | 11.13 | 9.81 | 113 | 341673 | 28020 | 55922261 |
Abnormal behaviour | 11.13 | 9.81 | 179 | 341607 | 20093 | 55930188 |
Burns second degree | 11.08 | 9.81 | 18 | 341768 | 744 | 55949537 |
Device dislocation | 11.06 | 9.81 | 86 | 341700 | 22520 | 55927761 |
Spinal stenosis | 11.05 | 9.81 | 132 | 341654 | 13882 | 55936399 |
Confusional arousal | 11.05 | 9.81 | 7 | 341779 | 88 | 55950193 |
Impaired gastric emptying | 11.05 | 9.81 | 95 | 341691 | 9168 | 55941113 |
Nephrogenic systemic fibrosis | 11.02 | 9.81 | 55 | 341731 | 4410 | 55945871 |
Metabolic surgery | 11.02 | 9.81 | 23 | 341763 | 1155 | 55949126 |
Maternal exposure timing unspecified | 11.01 | 9.81 | 10 | 341776 | 5413 | 55944868 |
Femoral artery dissection | 11.00 | 9.81 | 5 | 341781 | 30 | 55950251 |
Toe operation | 10.95 | 9.81 | 17 | 341769 | 676 | 55949605 |
Diffuse large B-cell lymphoma | 10.93 | 9.81 | 16 | 341770 | 7000 | 55943281 |
Conversion disorder | 10.93 | 9.81 | 28 | 341758 | 1610 | 55948671 |
Application site vesicles | 10.89 | 9.81 | 25 | 341761 | 1340 | 55948941 |
Screaming | 10.88 | 9.81 | 42 | 341744 | 3012 | 55947269 |
Ligament sprain | 10.84 | 9.81 | 112 | 341674 | 11363 | 55938918 |
Pericardial effusion | 10.81 | 9.81 | 109 | 341677 | 27066 | 55923215 |
Pharyngeal swelling | 10.81 | 9.81 | 62 | 341724 | 5244 | 55945037 |
Polyarthritis | 10.80 | 9.81 | 23 | 341763 | 8705 | 55941576 |
Normal newborn | 10.72 | 9.81 | 18 | 341768 | 7452 | 55942829 |
Wrist fracture | 10.72 | 9.81 | 116 | 341670 | 11910 | 55938371 |
Acute hepatic failure | 10.69 | 9.81 | 58 | 341728 | 16520 | 55933761 |
Complication of device insertion | 10.66 | 9.81 | 14 | 341772 | 6410 | 55943871 |
Application site burn | 10.65 | 9.81 | 18 | 341768 | 769 | 55949512 |
Intervertebral disc disorder | 10.64 | 9.81 | 55 | 341731 | 4471 | 55945810 |
Malignant polyp | 10.64 | 9.81 | 9 | 341777 | 181 | 55950100 |
Metastases to lung | 10.63 | 9.81 | 36 | 341750 | 11682 | 55938599 |
Acute generalised exanthematous pustulosis | 10.62 | 9.81 | 28 | 341758 | 9841 | 55940440 |
Metastases to bone | 10.61 | 9.81 | 72 | 341714 | 19436 | 55930845 |
Vertebral foraminal stenosis | 10.60 | 9.81 | 19 | 341767 | 851 | 55949430 |
Stress | 10.56 | 9.81 | 448 | 341338 | 58462 | 55891819 |
Urinary occult blood positive | 10.55 | 9.81 | 6 | 341780 | 61 | 55950220 |
Scratch | 10.47 | 9.81 | 64 | 341722 | 5539 | 55944742 |
Cardiotoxicity | 10.47 | 9.81 | 19 | 341767 | 7631 | 55942650 |
Post procedural complication | 10.43 | 9.81 | 143 | 341643 | 15523 | 55934758 |
Hepatitis C virus test positive | 10.41 | 9.81 | 7 | 341779 | 98 | 55950183 |
Flushing | 10.39 | 9.81 | 523 | 341263 | 69577 | 55880704 |
Chorea | 10.33 | 9.81 | 25 | 341761 | 1387 | 55948894 |
Ulcer | 10.33 | 9.81 | 87 | 341699 | 22398 | 55927883 |
Enamel anomaly | 10.30 | 9.81 | 4 | 341782 | 15 | 55950266 |
Inflammation | 10.30 | 9.81 | 330 | 341456 | 68741 | 55881540 |
Acute coronary syndrome | 10.29 | 9.81 | 28 | 341758 | 9740 | 55940541 |
Intentional underdose | 10.29 | 9.81 | 28 | 341758 | 1670 | 55948611 |
Blood glucose decreased | 10.28 | 9.81 | 168 | 341618 | 18919 | 55931362 |
Premature ageing | 10.27 | 9.81 | 3 | 341783 | 3 | 55950278 |
Nervous system cyst | 10.27 | 9.81 | 3 | 341783 | 3 | 55950278 |
Diabetic gastropathy | 10.27 | 9.81 | 3 | 341783 | 3 | 55950278 |
Neurogenic bladder | 10.26 | 9.81 | 41 | 341745 | 2988 | 55947293 |
Slow speech | 10.25 | 9.81 | 24 | 341762 | 1303 | 55948978 |
Empty sella syndrome | 10.25 | 9.81 | 5 | 341781 | 36 | 55950245 |
Eyelid myoclonus | 10.23 | 9.81 | 7 | 341779 | 101 | 55950180 |
Dependence | 10.23 | 9.81 | 31 | 341755 | 1966 | 55948315 |
Colorectal cancer | 10.22 | 9.81 | 4 | 341782 | 3425 | 55946856 |
Product adhesion issue | 10.21 | 9.81 | 54 | 341732 | 4429 | 55945852 |
Respiratory rate decreased | 10.14 | 9.81 | 43 | 341743 | 3219 | 55947062 |
Decreased interest | 10.14 | 9.81 | 41 | 341745 | 3005 | 55947276 |
Uveitis | 10.12 | 9.81 | 34 | 341752 | 11061 | 55939220 |
Blood bilirubin increased | 10.11 | 9.81 | 142 | 341644 | 33212 | 55917069 |
Hypercalcaemia | 10.08 | 9.81 | 102 | 341684 | 25309 | 55924972 |
Retroplacental haematoma | 10.06 | 9.81 | 8 | 341778 | 147 | 55950134 |
Face injury | 10.06 | 9.81 | 40 | 341746 | 2909 | 55947372 |
Haemorrhage | 10.03 | 9.81 | 263 | 341523 | 56134 | 55894147 |
Laryngeal dyspnoea | 10.02 | 9.81 | 8 | 341778 | 148 | 55950133 |
Disturbance in social behaviour | 10.01 | 9.81 | 3 | 341783 | 3038 | 55947243 |
Uterine perforation | 9.98 | 9.81 | 15 | 341771 | 6490 | 55943791 |
Dysphonia | 9.93 | 9.81 | 329 | 341457 | 41618 | 55908663 |
Copper deficiency | 9.93 | 9.81 | 6 | 341780 | 69 | 55950212 |
Nerve root injury | 9.91 | 9.81 | 5 | 341781 | 39 | 55950242 |
Sciatic nerve injury | 9.90 | 9.81 | 13 | 341773 | 442 | 55949839 |
Neck surgery | 9.88 | 9.81 | 28 | 341758 | 1710 | 55948571 |
Radiation necrosis | 9.87 | 9.81 | 12 | 341774 | 377 | 55949904 |
Soft tissue disorder | 9.81 | 9.81 | 7 | 341779 | 4275 | 55946006 |
Eyelid contusion | 9.81 | 9.81 | 3 | 341783 | 4 | 55950277 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 869.65 | 10.58 | 1543 | 184888 | 71056 | 31439857 |
Completed suicide | 488.16 | 10.58 | 1410 | 185021 | 90104 | 31420809 |
Drug ineffective for unapproved indication | 462.89 | 10.58 | 547 | 185884 | 17243 | 31493670 |
Myoclonus | 279.34 | 10.58 | 377 | 186054 | 13613 | 31497300 |
Somnolence | 201.17 | 10.58 | 1132 | 185299 | 98313 | 31412600 |
Drug abuse | 190.24 | 10.58 | 1018 | 185413 | 86740 | 31424173 |
Toxicity to various agents | 188.83 | 10.58 | 1760 | 184671 | 179727 | 31331186 |
Neuropathy peripheral | 180.93 | 10.58 | 902 | 185529 | 74747 | 31436166 |
Drug withdrawal syndrome | 157.77 | 10.58 | 344 | 186087 | 18406 | 31492507 |
Sedation | 150.62 | 10.58 | 340 | 186091 | 18625 | 31492288 |
Interstitial lung disease | 150.52 | 10.58 | 87 | 186344 | 61316 | 31449597 |
Fall | 145.83 | 10.58 | 1704 | 184727 | 184385 | 31326528 |
Drug dependence | 144.13 | 10.58 | 372 | 186059 | 22207 | 31488706 |
Multiple sclerosis relapse | 133.63 | 10.58 | 248 | 186183 | 11799 | 31499114 |
Pain | 123.50 | 10.58 | 1657 | 184774 | 185102 | 31325811 |
Febrile neutropenia | 118.36 | 10.58 | 347 | 186084 | 121502 | 31389411 |
Memory impairment | 118.21 | 10.58 | 491 | 185940 | 37639 | 31473274 |
Neuralgia | 109.41 | 10.58 | 226 | 186205 | 11640 | 31499273 |
Euphoric mood | 108.11 | 10.58 | 139 | 186292 | 4781 | 31506132 |
Hypoaesthesia | 105.49 | 10.58 | 626 | 185805 | 55396 | 31455517 |
Confusional state | 105.21 | 10.58 | 1223 | 185208 | 132111 | 31378802 |
Mental status changes | 101.36 | 10.58 | 450 | 185981 | 35518 | 31475395 |
Insomnia | 97.00 | 10.58 | 917 | 185514 | 93919 | 31416994 |
Tremor | 94.79 | 10.58 | 771 | 185660 | 75649 | 31435264 |
Hepatic function abnormal | 94.64 | 10.58 | 63 | 186368 | 41159 | 31469754 |
Cytomegalovirus infection | 94.06 | 10.58 | 16 | 186415 | 24691 | 31486222 |
Withdrawal syndrome | 92.96 | 10.58 | 210 | 186221 | 11507 | 31499406 |
Depression | 92.82 | 10.58 | 878 | 185553 | 89937 | 31420976 |
Cardiac failure | 90.72 | 10.58 | 235 | 186196 | 85718 | 31425195 |
Pain in extremity | 88.15 | 10.58 | 1058 | 185373 | 115145 | 31395768 |
Anaemia | 87.26 | 10.58 | 819 | 185612 | 212703 | 31298210 |
Pyrexia | 86.09 | 10.58 | 1264 | 185167 | 302576 | 31208337 |
Therapeutic product effect variable | 83.42 | 10.58 | 78 | 186353 | 1860 | 31509053 |
Obsessive-compulsive disorder | 82.18 | 10.58 | 122 | 186309 | 4815 | 31506098 |
Gait disturbance | 81.06 | 10.58 | 753 | 185678 | 76742 | 31434171 |
Respiratory arrest | 78.16 | 10.58 | 334 | 186097 | 25923 | 31484990 |
Renal impairment | 78.05 | 10.58 | 254 | 186177 | 86095 | 31424818 |
C-reactive protein increased | 77.99 | 10.58 | 103 | 186328 | 48547 | 31462366 |
Balance disorder | 76.19 | 10.58 | 427 | 186004 | 36995 | 31473918 |
Thrombocytopenia | 74.65 | 10.58 | 512 | 185919 | 142235 | 31368678 |
Dizziness | 72.08 | 10.58 | 1604 | 184827 | 197543 | 31313370 |
Antipsychotic drug level below therapeutic | 69.77 | 10.58 | 72 | 186359 | 1943 | 31508970 |
Disinhibition | 68.68 | 10.58 | 82 | 186349 | 2611 | 31508302 |
Drug resistance | 68.59 | 10.58 | 26 | 186405 | 23427 | 31487486 |
Muscle spasms | 68.03 | 10.58 | 657 | 185774 | 67661 | 31443252 |
Anxiety | 67.75 | 10.58 | 826 | 185605 | 90207 | 31420706 |
Nightmare | 66.44 | 10.58 | 189 | 186242 | 11948 | 31498965 |
Suicidal ideation | 64.81 | 10.58 | 401 | 186030 | 36005 | 31474908 |
Neutropenia | 64.07 | 10.58 | 523 | 185908 | 139841 | 31371072 |
Mucosal inflammation | 61.44 | 10.58 | 67 | 186364 | 34360 | 31476553 |
Muscle spasticity | 61.23 | 10.58 | 115 | 186316 | 5520 | 31505393 |
Alanine aminotransferase increased | 60.49 | 10.58 | 230 | 186201 | 74426 | 31436487 |
Product complaint | 60.36 | 10.58 | 113 | 186318 | 5411 | 31505502 |
Feeling abnormal | 60.14 | 10.58 | 555 | 185876 | 56447 | 31454466 |
Septic shock | 57.44 | 10.58 | 198 | 186233 | 65960 | 31444953 |
Appendicolith | 57.42 | 10.58 | 113 | 186318 | 5618 | 31505295 |
Hallucination | 57.38 | 10.58 | 468 | 185963 | 45942 | 31464971 |
Intervertebral disc degeneration | 57.22 | 10.58 | 111 | 186320 | 5460 | 31505453 |
Accidental death | 55.71 | 10.58 | 67 | 186364 | 2150 | 31508763 |
Overdose | 55.30 | 10.58 | 750 | 185681 | 83914 | 31426999 |
Respiratory depression | 54.86 | 10.58 | 199 | 186232 | 14311 | 31496602 |
Dysarthria | 54.71 | 10.58 | 349 | 186082 | 31668 | 31479245 |
Right atrial hypertrophy | 54.33 | 10.58 | 38 | 186393 | 589 | 31510324 |
Disseminated intravascular coagulation | 53.36 | 10.58 | 27 | 186404 | 20510 | 31490403 |
Increased appetite | 52.90 | 10.58 | 116 | 186315 | 6228 | 31504685 |
Intentional product misuse | 52.60 | 10.58 | 393 | 186038 | 37558 | 31473355 |
Burning sensation | 49.04 | 10.58 | 212 | 186219 | 16535 | 31494378 |
Amnesia | 48.93 | 10.58 | 269 | 186162 | 23133 | 31487780 |
Multiple sclerosis | 47.80 | 10.58 | 129 | 186302 | 7908 | 31503005 |
Bone marrow failure | 47.27 | 10.58 | 57 | 186374 | 27951 | 31482962 |
Drug reaction with eosinophilia and systemic symptoms | 46.64 | 10.58 | 65 | 186366 | 29953 | 31480960 |
Back disorder | 45.89 | 10.58 | 107 | 186324 | 5986 | 31504927 |
Fatigue | 45.01 | 10.58 | 2405 | 184026 | 332801 | 31178112 |
Haemophagocytic lymphohistiocytosis | 43.49 | 10.58 | 8 | 186423 | 11670 | 31499243 |
Paraesthesia | 42.65 | 10.58 | 511 | 185920 | 55560 | 31455353 |
Myokymia | 42.15 | 10.58 | 17 | 186414 | 75 | 31510838 |
Constipation | 41.75 | 10.58 | 989 | 185442 | 123002 | 31387911 |
Malignant neoplasm progression | 41.41 | 10.58 | 283 | 186148 | 78715 | 31432198 |
Vision blurred | 41.16 | 10.58 | 402 | 186029 | 41513 | 31469400 |
Serotonin syndrome | 40.74 | 10.58 | 218 | 186213 | 18555 | 31492358 |
Bronchial secretion retention | 40.65 | 10.58 | 44 | 186387 | 1256 | 31509657 |
Prescription drug used without a prescription | 40.63 | 10.58 | 46 | 186385 | 1382 | 31509531 |
Off label use | 40.38 | 10.58 | 1652 | 184779 | 345622 | 31165291 |
Ataxia | 40.12 | 10.58 | 166 | 186265 | 12697 | 31498216 |
Myelosuppression | 39.69 | 10.58 | 19 | 186412 | 14901 | 31496012 |
Rheumatoid arthritis | 39.55 | 10.58 | 146 | 186285 | 47663 | 31463250 |
Multiple organ dysfunction syndrome | 39.49 | 10.58 | 237 | 186194 | 67966 | 31442947 |
Depressed level of consciousness | 37.80 | 10.58 | 370 | 186061 | 38231 | 31472682 |
Needle fatigue | 37.75 | 10.58 | 33 | 186398 | 719 | 31510194 |
Sleep apnoea syndrome | 37.55 | 10.58 | 212 | 186219 | 18413 | 31492500 |
Inadequate analgesia | 37.10 | 10.58 | 61 | 186370 | 2632 | 31508281 |
Relapsing-remitting multiple sclerosis | 37.04 | 10.58 | 36 | 186395 | 902 | 31510011 |
Bronchial wall thickening | 37.03 | 10.58 | 40 | 186391 | 1139 | 31509774 |
Bronchopulmonary aspergillosis | 36.83 | 10.58 | 17 | 186414 | 13617 | 31497296 |
Aspergillus infection | 36.81 | 10.58 | 11 | 186420 | 11517 | 31499396 |
Dyspnoea | 36.78 | 10.58 | 1649 | 184782 | 341830 | 31169083 |
Hypokalaemia | 36.07 | 10.58 | 177 | 186254 | 53397 | 31457516 |
Infusion related reaction | 35.17 | 10.58 | 154 | 186277 | 47901 | 31463012 |
General physical health deterioration | 35.14 | 10.58 | 463 | 185968 | 112972 | 31397941 |
Hepatic failure | 34.78 | 10.58 | 89 | 186342 | 32613 | 31478300 |
Aspartate aminotransferase increased | 34.72 | 10.58 | 221 | 186210 | 62498 | 31448415 |
Muscle twitching | 34.68 | 10.58 | 117 | 186314 | 8113 | 31502800 |
Melaena | 34.63 | 10.58 | 89 | 186342 | 32565 | 31478348 |
Right ventricular hypertrophy | 34.57 | 10.58 | 40 | 186391 | 1231 | 31509682 |
Gait spastic | 34.47 | 10.58 | 34 | 186397 | 868 | 31510045 |
Foetal exposure during pregnancy | 34.35 | 10.58 | 124 | 186307 | 40752 | 31470161 |
Colitis ulcerative | 34.24 | 10.58 | 35 | 186396 | 18494 | 31492419 |
Neutrophil count decreased | 33.76 | 10.58 | 149 | 186282 | 46245 | 31464668 |
Appendicitis | 33.46 | 10.58 | 145 | 186286 | 11320 | 31499593 |
Jaundice | 33.33 | 10.58 | 81 | 186350 | 30206 | 31480707 |
Congenital multiplex arthrogryposis | 33.23 | 10.58 | 13 | 186418 | 52 | 31510861 |
Sopor | 32.88 | 10.58 | 145 | 186286 | 11407 | 31499506 |
Acute kidney injury | 32.81 | 10.58 | 1329 | 185102 | 278385 | 31232528 |
Antidepressant drug level above therapeutic | 32.79 | 10.58 | 19 | 186412 | 208 | 31510705 |
Renal failure | 32.74 | 10.58 | 519 | 185912 | 122811 | 31388102 |
Diabetic neuropathy | 32.69 | 10.58 | 72 | 186359 | 3877 | 31507036 |
Contraindicated product administered | 32.56 | 10.58 | 41 | 186390 | 19731 | 31491182 |
Cerebral haemorrhage | 32.12 | 10.58 | 93 | 186338 | 32719 | 31478194 |
Asterixis | 32.07 | 10.58 | 37 | 186394 | 1135 | 31509778 |
Product dose omission issue | 31.89 | 10.58 | 830 | 185601 | 104756 | 31406157 |
Back pain | 31.87 | 10.58 | 856 | 185575 | 108557 | 31402356 |
Colitis | 31.77 | 10.58 | 98 | 186333 | 33789 | 31477124 |
Labelled drug-drug interaction medication error | 31.74 | 10.58 | 19 | 186412 | 13144 | 31497769 |
Obstruction | 31.70 | 10.58 | 50 | 186381 | 2082 | 31508831 |
Prostate cancer | 31.64 | 10.58 | 114 | 186317 | 37487 | 31473426 |
Restless legs syndrome | 31.57 | 10.58 | 109 | 186322 | 7647 | 31503266 |
Graft versus host disease | 31.53 | 10.58 | 11 | 186420 | 10436 | 31500477 |
Full blood count decreased | 31.21 | 10.58 | 185 | 186246 | 16355 | 31494558 |
Lethargy | 31.08 | 10.58 | 356 | 186075 | 38285 | 31472628 |
Eosinophilia | 30.78 | 10.58 | 56 | 186375 | 23197 | 31487716 |
Metabolic acidosis | 30.71 | 10.58 | 124 | 186307 | 39453 | 31471460 |
Toxic epidermal necrolysis | 30.60 | 10.58 | 42 | 186389 | 19482 | 31491431 |
Victim of child abuse | 30.52 | 10.58 | 32 | 186399 | 880 | 31510033 |
Adverse drug reaction | 29.99 | 10.58 | 252 | 186179 | 24949 | 31485964 |
Sweat gland disorder | 29.81 | 10.58 | 14 | 186417 | 95 | 31510818 |
Hyperreflexia | 29.36 | 10.58 | 58 | 186373 | 2891 | 31508022 |
Blood bilirubin increased | 29.25 | 10.58 | 107 | 186324 | 35029 | 31475884 |
Sciatica | 29.06 | 10.58 | 83 | 186348 | 5258 | 31505655 |
Parasomnia | 28.68 | 10.58 | 21 | 186410 | 351 | 31510562 |
Mood altered | 28.67 | 10.58 | 111 | 186320 | 8235 | 31502678 |
Haematotoxicity | 28.58 | 10.58 | 4 | 186427 | 7133 | 31503780 |
Pleural effusion | 28.55 | 10.58 | 292 | 186139 | 74628 | 31436285 |
Gastrointestinal haemorrhage | 28.55 | 10.58 | 329 | 186102 | 82220 | 31428693 |
Pneumonitis | 28.48 | 10.58 | 89 | 186342 | 30563 | 31480350 |
Proteinuria | 28.41 | 10.58 | 34 | 186397 | 16729 | 31494184 |
Atrial fibrillation | 28.16 | 10.58 | 485 | 185946 | 113298 | 31397615 |
Analgesic drug level above therapeutic | 28.04 | 10.58 | 19 | 186412 | 279 | 31510634 |
Drug tolerance | 27.99 | 10.58 | 52 | 186379 | 2475 | 31508438 |
Synovitis | 27.88 | 10.58 | 19 | 186412 | 12264 | 31498649 |
Gamma-glutamyltransferase increased | 27.87 | 10.58 | 78 | 186353 | 27747 | 31483166 |
Nervousness | 27.66 | 10.58 | 140 | 186291 | 11660 | 31499253 |
Bradyphrenia | 27.52 | 10.58 | 72 | 186359 | 4332 | 31506581 |
Nerve injury | 27.49 | 10.58 | 60 | 186371 | 3211 | 31507702 |
Erectile dysfunction | 27.10 | 10.58 | 200 | 186231 | 19035 | 31491878 |
Pneumocystis jirovecii pneumonia | 26.90 | 10.58 | 41 | 186390 | 18210 | 31492703 |
Transaminases increased | 26.86 | 10.58 | 65 | 186366 | 24276 | 31486637 |
Haematochezia | 26.48 | 10.58 | 135 | 186296 | 40329 | 31470584 |
Dyskinesia | 26.45 | 10.58 | 212 | 186219 | 20698 | 31490215 |
Spinal operation | 26.36 | 10.58 | 51 | 186380 | 2503 | 31508410 |
Peripheral swelling | 26.18 | 10.58 | 552 | 185879 | 67313 | 31443600 |
Acute myocardial infarction | 26.16 | 10.58 | 183 | 186248 | 50640 | 31460273 |
Erythema | 26.07 | 10.58 | 325 | 186106 | 80080 | 31430833 |
Disorientation | 25.98 | 10.58 | 286 | 186145 | 30458 | 31480455 |
Acute respiratory distress syndrome | 25.93 | 10.58 | 67 | 186364 | 24473 | 31486440 |
Drug eruption | 25.72 | 10.58 | 42 | 186389 | 18145 | 31492768 |
Tooth disorder | 25.66 | 10.58 | 122 | 186309 | 9907 | 31501006 |
Schizophrenia | 25.60 | 10.58 | 16 | 186415 | 10814 | 31500099 |
Acute myeloid leukaemia | 25.59 | 10.58 | 44 | 186387 | 18628 | 31492285 |
Post transplant lymphoproliferative disorder | 25.31 | 10.58 | 3 | 186428 | 6073 | 31504840 |
Anger | 25.22 | 10.58 | 131 | 186300 | 11022 | 31499891 |
Hyperaesthesia | 25.10 | 10.58 | 65 | 186366 | 3886 | 31507027 |
Hypernatraemia | 25.04 | 10.58 | 7 | 186424 | 7656 | 31503257 |
Trigeminal neuralgia | 25.01 | 10.58 | 32 | 186399 | 1095 | 31509818 |
Pulmonary function test abnormal | 24.97 | 10.58 | 46 | 186385 | 2175 | 31508738 |
Delirium tremens | 24.90 | 10.58 | 24 | 186407 | 595 | 31510318 |
Circulatory collapse | 24.86 | 10.58 | 49 | 186382 | 19695 | 31491218 |
Pathogen resistance | 24.85 | 10.58 | 10 | 186421 | 8691 | 31502222 |
Anorgasmia | 24.83 | 10.58 | 26 | 186405 | 714 | 31510199 |
Cholangitis | 24.81 | 10.58 | 8 | 186423 | 7978 | 31502935 |
Gait inability | 24.71 | 10.58 | 195 | 186236 | 18949 | 31491964 |
Delirium | 24.63 | 10.58 | 361 | 186070 | 41060 | 31469853 |
Hallucination, visual | 24.45 | 10.58 | 168 | 186263 | 15626 | 31495287 |
Pancytopenia | 24.33 | 10.58 | 364 | 186067 | 86952 | 31423961 |
Aortic valve stenosis | 24.23 | 10.58 | 48 | 186383 | 2398 | 31508515 |
Venoocclusive liver disease | 23.80 | 10.58 | 7 | 186424 | 7405 | 31503508 |
Hypertonic bladder | 23.58 | 10.58 | 39 | 186392 | 1691 | 31509222 |
Hepatic enzyme increased | 23.38 | 10.58 | 120 | 186311 | 35788 | 31475125 |
Posterior reversible encephalopathy syndrome | 23.33 | 10.58 | 13 | 186418 | 9354 | 31501559 |
Epistaxis | 23.16 | 10.58 | 203 | 186228 | 53504 | 31457409 |
Angioedema | 22.66 | 10.58 | 111 | 186320 | 33507 | 31477406 |
Cholestasis | 22.46 | 10.58 | 74 | 186357 | 25001 | 31485912 |
Pulmonary alveolar haemorrhage | 22.45 | 10.58 | 6 | 186425 | 6760 | 31504153 |
Encephalopathy neonatal | 22.26 | 10.58 | 9 | 186422 | 40 | 31510873 |
Coordination abnormal | 22.16 | 10.58 | 93 | 186338 | 7158 | 31503755 |
Drug screen negative | 21.93 | 10.58 | 13 | 186418 | 149 | 31510764 |
Suicidal behaviour | 21.87 | 10.58 | 34 | 186397 | 1398 | 31509515 |
Cerebral infarction | 21.69 | 10.58 | 79 | 186352 | 25898 | 31485015 |
Inflammation | 21.59 | 10.58 | 76 | 186355 | 25165 | 31485748 |
Urinary incontinence | 21.58 | 10.58 | 175 | 186256 | 17145 | 31493768 |
Monoparesis | 21.33 | 10.58 | 42 | 186389 | 2089 | 31508824 |
Neonatal toxicity | 21.27 | 10.58 | 8 | 186423 | 28 | 31510885 |
Irritability | 21.24 | 10.58 | 217 | 186214 | 22672 | 31488241 |
Anaphylactic reaction | 20.84 | 10.58 | 96 | 186335 | 29457 | 31481456 |
Acute hepatic failure | 20.83 | 10.58 | 27 | 186404 | 12832 | 31498081 |
Palmar-plantar erythrodysaesthesia syndrome | 20.75 | 10.58 | 37 | 186394 | 15446 | 31495467 |
Transplant rejection | 20.75 | 10.58 | 16 | 186415 | 9692 | 31501221 |
Phantom limb syndrome | 20.63 | 10.58 | 15 | 186416 | 248 | 31510665 |
Fibromyalgia | 20.60 | 10.58 | 49 | 186382 | 2777 | 31508136 |
Drug tolerance increased | 20.53 | 10.58 | 19 | 186412 | 447 | 31510466 |
Osteomyelitis | 20.49 | 10.58 | 152 | 186279 | 14491 | 31496422 |
Blood lactate dehydrogenase increased | 20.38 | 10.58 | 57 | 186374 | 20282 | 31490631 |
Rash maculo-papular | 20.32 | 10.58 | 80 | 186351 | 25639 | 31485274 |
Myocarditis | 20.31 | 10.58 | 24 | 186407 | 11876 | 31499037 |
Affective disorder | 20.27 | 10.58 | 58 | 186373 | 3678 | 31507235 |
Shock haemorrhagic | 20.23 | 10.58 | 18 | 186413 | 10159 | 31500754 |
Agranulocytosis | 20.23 | 10.58 | 61 | 186370 | 21186 | 31489727 |
Blood creatine phosphokinase increased | 20.22 | 10.58 | 154 | 186277 | 41820 | 31469093 |
Disease progression | 20.06 | 10.58 | 393 | 186038 | 90071 | 31420842 |
Impaired driving ability | 19.88 | 10.58 | 44 | 186387 | 2377 | 31508536 |
Accidental poisoning | 19.87 | 10.58 | 23 | 186408 | 708 | 31510205 |
Epstein-Barr virus infection | 19.85 | 10.58 | 8 | 186423 | 6945 | 31503968 |
Lower respiratory tract infection | 19.75 | 10.58 | 92 | 186339 | 28145 | 31482768 |
Treatment failure | 19.49 | 10.58 | 150 | 186281 | 40642 | 31470271 |
Nephropathy toxic | 19.27 | 10.58 | 23 | 186408 | 11330 | 31499583 |
Personality change | 19.18 | 10.58 | 67 | 186364 | 4728 | 31506185 |
Head titubation | 19.15 | 10.58 | 16 | 186415 | 327 | 31510586 |
Ischaemic stroke | 18.97 | 10.58 | 45 | 186386 | 16926 | 31493987 |
Localised infection | 18.89 | 10.58 | 154 | 186277 | 15111 | 31495802 |
Mental impairment | 18.88 | 10.58 | 108 | 186323 | 9424 | 31501489 |
Tuberculosis | 18.80 | 10.58 | 13 | 186418 | 8328 | 31502585 |
Agitation | 18.79 | 10.58 | 434 | 185997 | 53735 | 31457178 |
Cardio-respiratory arrest | 18.75 | 10.58 | 417 | 186014 | 51309 | 31459604 |
Brief psychotic disorder with marked stressors | 18.72 | 10.58 | 13 | 186418 | 199 | 31510714 |
Conversion disorder | 18.71 | 10.58 | 16 | 186415 | 338 | 31510575 |
Facial pain | 18.71 | 10.58 | 38 | 186393 | 1933 | 31508980 |
Tumour lysis syndrome | 18.67 | 10.58 | 39 | 186392 | 15346 | 31495567 |
Intervertebral disc protrusion | 18.62 | 10.58 | 104 | 186327 | 8996 | 31501917 |
Nephrotic syndrome | 18.50 | 10.58 | 9 | 186422 | 6994 | 31503919 |
Muscular weakness | 18.18 | 10.58 | 509 | 185922 | 64939 | 31445974 |
Lumbar radiculopathy | 18.11 | 10.58 | 23 | 186408 | 781 | 31510132 |
Prescribed overdose | 18.11 | 10.58 | 104 | 186327 | 9088 | 31501825 |
Rhabdomyolysis | 18.07 | 10.58 | 264 | 186167 | 63317 | 31447596 |
Migraine | 18.06 | 10.58 | 144 | 186287 | 14036 | 31496877 |
Cognitive disorder | 18.01 | 10.58 | 225 | 186206 | 24698 | 31486215 |
Haemolysis | 17.99 | 10.58 | 10 | 186421 | 7206 | 31503707 |
Thrombosis | 17.97 | 10.58 | 369 | 186062 | 44782 | 31466131 |
Mucosal atrophy | 17.82 | 10.58 | 9 | 186422 | 73 | 31510840 |
Hostility | 17.82 | 10.58 | 23 | 186408 | 794 | 31510119 |
Tubulointerstitial nephritis | 17.68 | 10.58 | 53 | 186378 | 18443 | 31492470 |
Rectal haemorrhage | 17.58 | 10.58 | 133 | 186298 | 36171 | 31474742 |
Facial wasting | 17.57 | 10.58 | 11 | 186420 | 140 | 31510773 |
Binocular eye movement disorder | 17.45 | 10.58 | 8 | 186423 | 51 | 31510862 |
Hyperbilirubinaemia | 17.42 | 10.58 | 42 | 186389 | 15708 | 31495205 |
Pulmonary toxicity | 17.41 | 10.58 | 5 | 186426 | 5372 | 31505541 |
Sedation complication | 17.40 | 10.58 | 31 | 186400 | 1428 | 31509485 |
Cerebral disorder | 17.40 | 10.58 | 42 | 186389 | 2403 | 31508510 |
Dysphoria | 17.30 | 10.58 | 39 | 186392 | 2133 | 31508780 |
Ear deformity acquired | 17.27 | 10.58 | 5 | 186426 | 5 | 31510908 |
Breakthrough pain | 17.23 | 10.58 | 19 | 186412 | 554 | 31510359 |
Therapeutic response unexpected | 17.07 | 10.58 | 101 | 186330 | 8923 | 31501990 |
Suspected suicide | 16.96 | 10.58 | 58 | 186373 | 4049 | 31506864 |
Cough | 16.96 | 10.58 | 635 | 185796 | 134179 | 31376734 |
Violence-related symptom | 16.91 | 10.58 | 18 | 186413 | 504 | 31510409 |
Opisthotonus | 16.89 | 10.58 | 17 | 186414 | 445 | 31510468 |
Immune reconstitution inflammatory syndrome | 16.82 | 10.58 | 14 | 186417 | 8164 | 31502749 |
Hypoacusis | 16.80 | 10.58 | 148 | 186283 | 14851 | 31496062 |
Liver disorder | 16.78 | 10.58 | 104 | 186327 | 29603 | 31481310 |
Ventricular tachycardia | 16.71 | 10.58 | 77 | 186354 | 23624 | 31487289 |
Precancerous skin lesion | 16.70 | 10.58 | 19 | 186412 | 574 | 31510339 |
Stress | 16.69 | 10.58 | 222 | 186209 | 24719 | 31486194 |
Haemoglobin decreased | 16.66 | 10.58 | 520 | 185911 | 112155 | 31398758 |
Idiopathic neutropenia | 16.57 | 10.58 | 4 | 186427 | 0 | 31510913 |
Blood pressure fluctuation | 16.55 | 10.58 | 73 | 186358 | 22663 | 31488250 |
Bradypnoea | 16.28 | 10.58 | 42 | 186389 | 2505 | 31508408 |
Quality of life decreased | 16.25 | 10.58 | 51 | 186380 | 3404 | 31507509 |
Haematuria | 16.23 | 10.58 | 184 | 186247 | 46130 | 31464783 |
Encephalitis | 16.20 | 10.58 | 10 | 186421 | 6805 | 31504108 |
Panic attack | 16.20 | 10.58 | 97 | 186334 | 8606 | 31502307 |
Intentional product use issue | 16.16 | 10.58 | 199 | 186232 | 49148 | 31461765 |
Metabolic encephalopathy | 16.13 | 10.58 | 55 | 186376 | 3834 | 31507079 |
Plasma cell myeloma | 16.08 | 10.58 | 441 | 185990 | 56090 | 31454823 |
Hyperhidrosis | 15.98 | 10.58 | 514 | 185917 | 66879 | 31444034 |
Pulmonary tuberculosis | 15.97 | 10.58 | 4 | 186427 | 4707 | 31506206 |
Loss of proprioception | 15.96 | 10.58 | 15 | 186416 | 360 | 31510553 |
Feeding intolerance | 15.92 | 10.58 | 10 | 186421 | 128 | 31510785 |
Hypertransaminasaemia | 15.92 | 10.58 | 3 | 186428 | 4301 | 31506612 |
Thinking abnormal | 15.89 | 10.58 | 70 | 186361 | 5503 | 31505410 |
Hypomagnesaemia | 15.89 | 10.58 | 58 | 186373 | 19000 | 31491913 |
Cytomegalovirus viraemia | 15.81 | 10.58 | 10 | 186421 | 6715 | 31504198 |
Heat exhaustion | 15.79 | 10.58 | 10 | 186421 | 130 | 31510783 |
Pneumothorax | 15.78 | 10.58 | 49 | 186382 | 16861 | 31494052 |
Artery dissection | 15.73 | 10.58 | 9 | 186422 | 96 | 31510817 |
Bladder cancer | 15.71 | 10.58 | 40 | 186391 | 14685 | 31496228 |
Aggression | 15.59 | 10.58 | 307 | 186124 | 36984 | 31473929 |
Hypersomnia | 15.32 | 10.58 | 115 | 186316 | 11004 | 31499909 |
Autoimmune haemolytic anaemia | 15.23 | 10.58 | 3 | 186428 | 4169 | 31506744 |
Hypoalbuminaemia | 15.10 | 10.58 | 26 | 186405 | 11002 | 31499911 |
Gingival atrophy | 15.09 | 10.58 | 7 | 186424 | 46 | 31510867 |
Stevens-Johnson syndrome | 15.06 | 10.58 | 52 | 186379 | 17320 | 31493593 |
Acute coronary syndrome | 15.04 | 10.58 | 33 | 186398 | 12756 | 31498157 |
Foot fracture | 14.98 | 10.58 | 57 | 186374 | 4194 | 31506719 |
Mucormycosis | 14.96 | 10.58 | 7 | 186424 | 5563 | 31505350 |
Alcoholism | 14.92 | 10.58 | 49 | 186382 | 3350 | 31507563 |
Foetal disorder | 14.92 | 10.58 | 21 | 186410 | 789 | 31510124 |
Lung disorder | 14.89 | 10.58 | 120 | 186311 | 32192 | 31478721 |
Dry mouth | 14.86 | 10.58 | 214 | 186217 | 24244 | 31486669 |
Metastases to liver | 14.83 | 10.58 | 33 | 186398 | 12694 | 31498219 |
Hyperthyroidism | 14.81 | 10.58 | 21 | 186410 | 9610 | 31501303 |
Left ventricular dysfunction | 14.79 | 10.58 | 20 | 186411 | 9337 | 31501576 |
Hepatotoxicity | 14.79 | 10.58 | 60 | 186371 | 19066 | 31491847 |
Acute graft versus host disease in skin | 14.73 | 10.58 | 5 | 186426 | 4827 | 31506086 |
Acute pulmonary oedema | 14.70 | 10.58 | 12 | 186419 | 7064 | 31503849 |
Blood creatinine increased | 14.69 | 10.58 | 405 | 186026 | 88673 | 31422240 |
Personality disorder | 14.66 | 10.58 | 25 | 186406 | 1112 | 31509801 |
Hepatocellular injury | 14.60 | 10.58 | 71 | 186360 | 21473 | 31489440 |
Nerve compression | 14.59 | 10.58 | 44 | 186387 | 2874 | 31508039 |
Feeling drunk | 14.58 | 10.58 | 32 | 186399 | 1719 | 31509194 |
Shock | 14.56 | 10.58 | 76 | 186355 | 22569 | 31488344 |
Muscle tightness | 14.56 | 10.58 | 59 | 186372 | 4470 | 31506443 |
Oesophageal mucosa erythema | 14.44 | 10.58 | 6 | 186425 | 29 | 31510884 |
Fungal infection | 14.42 | 10.58 | 41 | 186390 | 14510 | 31496403 |
Hypometabolism | 14.34 | 10.58 | 8 | 186423 | 81 | 31510832 |
Enterocolitis | 14.30 | 10.58 | 13 | 186418 | 7261 | 31503652 |
Akathisia | 14.25 | 10.58 | 82 | 186349 | 7171 | 31503742 |
Central nervous system lesion | 14.24 | 10.58 | 71 | 186360 | 5877 | 31505036 |
Hepatitis | 14.22 | 10.58 | 74 | 186357 | 21992 | 31488921 |
Gastric cancer | 14.19 | 10.58 | 9 | 186422 | 6036 | 31504877 |
Intentional underdose | 14.18 | 10.58 | 18 | 186413 | 611 | 31510302 |
Stomatitis | 14.09 | 10.58 | 156 | 186275 | 39282 | 31471631 |
Musculoskeletal disorder | 14.06 | 10.58 | 69 | 186362 | 5675 | 31505238 |
Body height decreased | 14.03 | 10.58 | 49 | 186382 | 3458 | 31507455 |
Micturition urgency | 13.96 | 10.58 | 69 | 186362 | 5691 | 31505222 |
Back injury | 13.95 | 10.58 | 51 | 186380 | 3681 | 31507232 |
Respiratory disorder | 13.94 | 10.58 | 56 | 186375 | 17844 | 31493069 |
Seizure | 13.93 | 10.58 | 719 | 185712 | 99049 | 31411864 |
Oesophageal carcinoma | 13.93 | 10.58 | 16 | 186415 | 8017 | 31502896 |
Peritonitis | 13.89 | 10.58 | 45 | 186386 | 15282 | 31495631 |
Haemorrhage intracranial | 13.88 | 10.58 | 44 | 186387 | 15044 | 31495869 |
Gastrointestinal adenocarcinoma | 13.84 | 10.58 | 7 | 186424 | 57 | 31510856 |
Radiculopathy | 13.83 | 10.58 | 40 | 186391 | 2552 | 31508361 |
Fear of weight gain | 13.82 | 10.58 | 4 | 186427 | 4 | 31510909 |
Psoriasis | 13.62 | 10.58 | 193 | 186238 | 46526 | 31464387 |
Oxygen saturation decreased | 13.58 | 10.58 | 205 | 186226 | 48910 | 31462003 |
Hepatocellular carcinoma | 13.56 | 10.58 | 19 | 186412 | 8737 | 31502176 |
Diplopia | 13.49 | 10.58 | 135 | 186296 | 14027 | 31496886 |
Abnormal labour affecting foetus | 13.40 | 10.58 | 5 | 186426 | 17 | 31510896 |
Alcohol withdrawal syndrome | 13.39 | 10.58 | 27 | 186404 | 1366 | 31509547 |
Cardiac failure acute | 13.30 | 10.58 | 23 | 186408 | 9718 | 31501195 |
Seborrhoeic keratosis | 13.30 | 10.58 | 21 | 186410 | 875 | 31510038 |
Dysphemia | 13.24 | 10.58 | 28 | 186403 | 1466 | 31509447 |
Road traffic accident | 13.20 | 10.58 | 151 | 186280 | 16230 | 31494683 |
Leukopenia | 13.18 | 10.58 | 250 | 186181 | 57578 | 31453335 |
Nephrolithiasis | 13.14 | 10.58 | 230 | 186201 | 27109 | 31483804 |
Colorectal cancer | 13.08 | 10.58 | 6 | 186425 | 4823 | 31506090 |
Spinal stenosis | 13.06 | 10.58 | 59 | 186372 | 4689 | 31506224 |
Abnormal sleep-related event | 13.06 | 10.58 | 15 | 186416 | 458 | 31510455 |
Pulmonary fibrosis | 13.05 | 10.58 | 52 | 186379 | 16608 | 31494305 |
Chest X-ray abnormal | 13.04 | 10.58 | 53 | 186378 | 4020 | 31506893 |
Hypertriglyceridaemia | 13.02 | 10.58 | 16 | 186415 | 7782 | 31503131 |
Ventricular hypokinesia | 12.97 | 10.58 | 6 | 186425 | 4800 | 31506113 |
Immature granulocyte percentage increased | 12.94 | 10.58 | 4 | 186427 | 6 | 31510907 |
Neutropenic sepsis | 12.92 | 10.58 | 34 | 186397 | 12345 | 31498568 |
Herpes zoster | 12.91 | 10.58 | 262 | 186169 | 31731 | 31479182 |
Stiff person syndrome | 12.90 | 10.58 | 8 | 186423 | 100 | 31510813 |
Cardiac arrest | 12.88 | 10.58 | 644 | 185787 | 88418 | 31422495 |
Drug abuser | 12.84 | 10.58 | 51 | 186380 | 3829 | 31507084 |
Sleep disorder | 12.78 | 10.58 | 222 | 186209 | 26126 | 31484787 |
Free androgen index decreased | 12.78 | 10.58 | 5 | 186426 | 20 | 31510893 |
Dependence | 12.73 | 10.58 | 23 | 186408 | 1071 | 31509842 |
Ventricular septal defect | 12.70 | 10.58 | 3 | 186428 | 3674 | 31507239 |
Hyperuricaemia | 12.69 | 10.58 | 15 | 186416 | 7423 | 31503490 |
Obesity | 12.68 | 10.58 | 110 | 186321 | 10990 | 31499923 |
Implant site inflammation | 12.63 | 10.58 | 8 | 186423 | 104 | 31510809 |
Chronic graft versus host disease | 12.62 | 10.58 | 5 | 186426 | 4387 | 31506526 |
Haemorrhage | 12.60 | 10.58 | 199 | 186232 | 47135 | 31463778 |
Epidural lipomatosis | 12.52 | 10.58 | 19 | 186412 | 765 | 31510148 |
Neoplasm progression | 12.50 | 10.58 | 69 | 186362 | 20203 | 31490710 |
Enterococcal infection | 12.50 | 10.58 | 20 | 186411 | 8711 | 31502202 |
Joint hyperextension | 12.44 | 10.58 | 8 | 186423 | 107 | 31510806 |
Tachycardia | 12.43 | 10.58 | 347 | 186084 | 75860 | 31435053 |
Benign neoplasm of spinal cord | 12.43 | 10.58 | 3 | 186428 | 0 | 31510913 |
Traumatic amputation | 12.43 | 10.58 | 3 | 186428 | 0 | 31510913 |
Pancreatic fibrosis | 12.43 | 10.58 | 3 | 186428 | 0 | 31510913 |
Nasal odour | 12.43 | 10.58 | 3 | 186428 | 0 | 31510913 |
Severe myoclonic epilepsy of infancy | 12.43 | 10.58 | 3 | 186428 | 0 | 31510913 |
Amphetamines positive | 12.42 | 10.58 | 9 | 186422 | 148 | 31510765 |
Neck surgery | 12.41 | 10.58 | 13 | 186418 | 357 | 31510556 |
Large intestine perforation | 12.40 | 10.58 | 16 | 186415 | 7620 | 31503293 |
Blood urea increased | 12.35 | 10.58 | 110 | 186321 | 28902 | 31482011 |
Disturbance in attention | 12.31 | 10.58 | 193 | 186238 | 22257 | 31488656 |
Immunosuppressant drug level increased | 12.23 | 10.58 | 8 | 186423 | 5277 | 31505636 |
Rales | 12.17 | 10.58 | 20 | 186411 | 8619 | 31502294 |
Enthesopathy | 12.13 | 10.58 | 5 | 186426 | 4282 | 31506631 |
Dysstasia | 12.09 | 10.58 | 109 | 186322 | 11009 | 31499904 |
Ejection fraction decreased | 12.08 | 10.58 | 57 | 186374 | 17377 | 31493536 |
Slow speech | 12.07 | 10.58 | 22 | 186409 | 1032 | 31509881 |
Bipolar I disorder | 11.98 | 10.58 | 19 | 186412 | 795 | 31510118 |
Candida infection | 11.95 | 10.58 | 52 | 186379 | 16206 | 31494707 |
Hypoosmolar state | 11.90 | 10.58 | 7 | 186424 | 79 | 31510834 |
Nocturia | 11.88 | 10.58 | 94 | 186337 | 9141 | 31501772 |
Anal abscess | 11.84 | 10.58 | 10 | 186421 | 5790 | 31505123 |
Hyperkalaemia | 11.82 | 10.58 | 288 | 186143 | 64063 | 31446850 |
Anaphylactic shock | 11.82 | 10.58 | 43 | 186388 | 14102 | 31496811 |
Rib fracture | 11.77 | 10.58 | 125 | 186306 | 13191 | 31497722 |
Neutrophil count increased | 11.76 | 10.58 | 50 | 186381 | 15681 | 31495232 |
Product communication issue | 11.65 | 10.58 | 12 | 186419 | 323 | 31510590 |
Drug withdrawal syndrome neonatal | 11.63 | 10.58 | 46 | 186385 | 3446 | 31507467 |
Inflammatory marker increased | 11.61 | 10.58 | 5 | 186426 | 4173 | 31506740 |
Hyperglycaemia | 11.60 | 10.58 | 148 | 186283 | 36328 | 31474585 |
Antipsychotic drug level increased | 11.60 | 10.58 | 3 | 186428 | 3455 | 31507458 |
Adrenal insufficiency | 11.59 | 10.58 | 37 | 186394 | 12622 | 31498291 |
Neutropenia neonatal | 11.58 | 10.58 | 17 | 186414 | 664 | 31510249 |
Blood pressure decreased | 11.56 | 10.58 | 206 | 186225 | 47885 | 31463028 |
Teeth brittle | 11.55 | 10.58 | 6 | 186425 | 52 | 31510861 |
Blood alkaline phosphatase increased | 11.54 | 10.58 | 114 | 186317 | 29339 | 31481574 |
Lactic acidosis | 11.54 | 10.58 | 126 | 186305 | 31811 | 31479102 |
Nephrogenic systemic fibrosis | 11.52 | 10.58 | 50 | 186381 | 3905 | 31507008 |
Multiple-drug resistance | 11.47 | 10.58 | 6 | 186425 | 4474 | 31506439 |
Open angle glaucoma | 11.45 | 10.58 | 9 | 186422 | 168 | 31510745 |
Therapy partial responder | 11.45 | 10.58 | 13 | 186418 | 6549 | 31504364 |
Thoracic vertebral fracture | 11.44 | 10.58 | 27 | 186404 | 1522 | 31509391 |
Asthma | 11.39 | 10.58 | 179 | 186252 | 42432 | 31468481 |
Pseudomonas infection | 11.39 | 10.58 | 32 | 186399 | 11369 | 31499544 |
Application site hypersensitivity | 11.38 | 10.58 | 8 | 186423 | 125 | 31510788 |
Mental disorder | 11.37 | 10.58 | 128 | 186303 | 13706 | 31497207 |
Uveitis | 11.36 | 10.58 | 14 | 186417 | 6802 | 31504111 |
Arrhythmia | 11.36 | 10.58 | 132 | 186299 | 32945 | 31477968 |
Myoclonic dystonia | 11.35 | 10.58 | 4 | 186427 | 11 | 31510902 |
Injection site mass | 11.33 | 10.58 | 66 | 186365 | 5798 | 31505115 |
Adenovirus infection | 11.27 | 10.58 | 7 | 186424 | 4747 | 31506166 |
Mouth ulceration | 11.17 | 10.58 | 30 | 186401 | 10818 | 31500095 |
Retinal haemorrhage | 11.16 | 10.58 | 7 | 186424 | 4723 | 31506190 |
Second primary malignancy | 11.15 | 10.58 | 15 | 186416 | 7017 | 31503896 |
Infective pulmonary exacerbation of cystic fibrosis | 11.15 | 10.58 | 13 | 186418 | 6471 | 31504442 |
Carpal tunnel syndrome | 11.12 | 10.58 | 53 | 186378 | 4308 | 31506605 |
Hip fracture | 11.09 | 10.58 | 106 | 186325 | 10880 | 31500033 |
Irritable bowel syndrome | 11.07 | 10.58 | 42 | 186389 | 3086 | 31507827 |
White blood cell count increased | 11.05 | 10.58 | 162 | 186269 | 38838 | 31472075 |
Post herpetic neuralgia | 11.04 | 10.58 | 21 | 186410 | 1018 | 31509895 |
Electric shock | 11.01 | 10.58 | 8 | 186423 | 132 | 31510781 |
Pneumonia bacterial | 10.96 | 10.58 | 28 | 186403 | 10268 | 31500645 |
Cyanosis | 10.95 | 10.58 | 34 | 186397 | 11701 | 31499212 |
Diastolic dysfunction | 10.93 | 10.58 | 61 | 186370 | 5274 | 31505639 |
Drug effective for unapproved indication | 10.92 | 10.58 | 30 | 186401 | 1858 | 31509055 |
Carcinogenicity | 10.90 | 10.58 | 6 | 186425 | 59 | 31510854 |
Lymphocyte count decreased | 10.79 | 10.58 | 74 | 186357 | 20575 | 31490338 |
Post laminectomy syndrome | 10.73 | 10.58 | 9 | 186422 | 185 | 31510728 |
Sleep attacks | 10.71 | 10.58 | 8 | 186423 | 138 | 31510775 |
Intestinal obstruction | 10.70 | 10.58 | 74 | 186357 | 20536 | 31490377 |
Complications of transplanted kidney | 10.68 | 10.58 | 6 | 186425 | 4299 | 31506614 |
Dysaesthesia | 10.64 | 10.58 | 32 | 186399 | 2087 | 31508826 |
Hypotony maculopathy | 10.63 | 10.58 | 4 | 186427 | 14 | 31510899 |
Lipodystrophy acquired | 10.63 | 10.58 | 3 | 186428 | 3261 | 31507652 |
Spinal fusion surgery | 10.62 | 10.58 | 19 | 186412 | 878 | 31510035 |
Cytokine release syndrome | 10.62 | 10.58 | 56 | 186375 | 16586 | 31494327 |
Toxic skin eruption | 10.60 | 10.58 | 28 | 186403 | 10152 | 31500761 |
Hepatitis B | 10.59 | 10.58 | 11 | 186420 | 5770 | 31505143 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 2722.73 | 9.84 | 5236 | 411555 | 257223 | 70254430 |
Completed suicide | 1392.60 | 9.84 | 3679 | 413112 | 223456 | 70288197 |
Drug ineffective for unapproved indication | 1365.70 | 9.84 | 1393 | 415398 | 37145 | 70474508 |
Myoclonus | 549.37 | 9.84 | 725 | 416066 | 25630 | 70486023 |
Toxicity to various agents | 517.86 | 9.84 | 3929 | 412862 | 378243 | 70133410 |
Drug abuse | 468.11 | 9.84 | 1909 | 414882 | 145347 | 70366306 |
Somnolence | 450.37 | 9.84 | 2474 | 414317 | 213132 | 70298521 |
Pemphigus | 447.33 | 9.84 | 8 | 416783 | 83028 | 70428625 |
Multiple sclerosis relapse | 434.02 | 9.84 | 850 | 415941 | 42167 | 70469486 |
Fall | 357.37 | 9.84 | 4084 | 412707 | 440012 | 70071641 |
Synovitis | 355.34 | 9.84 | 157 | 416634 | 129071 | 70382582 |
Hand deformity | 324.55 | 9.84 | 58 | 416733 | 86424 | 70425229 |
Pericarditis | 317.46 | 9.84 | 57 | 416734 | 84648 | 70427005 |
Contraindicated product administered | 315.06 | 9.84 | 201 | 416590 | 134411 | 70377242 |
Systemic lupus erythematosus | 304.40 | 9.84 | 109 | 416682 | 101793 | 70409860 |
Rheumatoid arthritis | 300.49 | 9.84 | 807 | 415984 | 290998 | 70220655 |
Maternal exposure during pregnancy | 285.69 | 9.84 | 161 | 416630 | 115184 | 70396469 |
Depression | 285.48 | 9.84 | 2075 | 414716 | 196899 | 70314754 |
Glossodynia | 267.88 | 9.84 | 87 | 416704 | 86400 | 70425253 |
Duodenal ulcer perforation | 263.44 | 9.84 | 8 | 416783 | 51104 | 70460549 |
Hepatic enzyme increased | 246.56 | 9.84 | 337 | 416454 | 156653 | 70355000 |
Rheumatoid factor positive | 237.72 | 9.84 | 11 | 416780 | 48389 | 70463264 |
Tremor | 234.79 | 9.84 | 1643 | 415148 | 153981 | 70357672 |
Respiratory arrest | 234.29 | 9.84 | 774 | 416017 | 53159 | 70458494 |
Infusion related reaction | 229.37 | 9.84 | 513 | 416278 | 197021 | 70314632 |
Mental status changes | 227.88 | 9.84 | 852 | 415939 | 62249 | 70449404 |
Memory impairment | 227.03 | 9.84 | 1112 | 415679 | 91529 | 70420124 |
Febrile neutropenia | 226.48 | 9.84 | 544 | 416247 | 203774 | 70307879 |
Helicobacter infection | 225.49 | 9.84 | 30 | 416761 | 55626 | 70456027 |
Neuralgia | 225.42 | 9.84 | 511 | 416280 | 28092 | 70483561 |
Drug dependence | 223.36 | 9.84 | 600 | 416191 | 36721 | 70474932 |
Interstitial lung disease | 221.66 | 9.84 | 174 | 416617 | 104511 | 70407142 |
Drug withdrawal syndrome | 220.54 | 9.84 | 550 | 416241 | 32165 | 70479488 |
Dizziness | 217.37 | 9.84 | 3882 | 412909 | 460259 | 70051394 |
Suicidal ideation | 205.88 | 9.84 | 883 | 415908 | 68713 | 70442940 |
Neuropathy peripheral | 204.03 | 9.84 | 1361 | 415430 | 125535 | 70386118 |
Accidental death | 201.36 | 9.84 | 174 | 416617 | 3734 | 70507919 |
Withdrawal syndrome | 195.24 | 9.84 | 444 | 416347 | 24460 | 70487193 |
Feeling abnormal | 193.65 | 9.84 | 1466 | 415325 | 140853 | 70370800 |
Arthropathy | 191.64 | 9.84 | 369 | 416422 | 149688 | 70361965 |
Joint swelling | 186.52 | 9.84 | 809 | 415982 | 252402 | 70259251 |
C-reactive protein increased | 181.93 | 9.84 | 229 | 416562 | 110288 | 70401365 |
General physical health deterioration | 181.33 | 9.84 | 742 | 416049 | 235289 | 70276364 |
Pyrexia | 179.31 | 9.84 | 2501 | 414290 | 604451 | 69907202 |
Hallucination | 176.66 | 9.84 | 901 | 415890 | 75359 | 70436294 |
Multiple sclerosis | 171.39 | 9.84 | 426 | 416365 | 24859 | 70486794 |
Sedation | 171.24 | 9.84 | 634 | 416157 | 46097 | 70465556 |
Exposure during pregnancy | 162.64 | 9.84 | 165 | 416626 | 87552 | 70424101 |
Muscle spasms | 159.19 | 9.84 | 1492 | 415299 | 152554 | 70359099 |
Sleep disorder due to general medical condition, insomnia type | 155.43 | 9.84 | 15 | 416776 | 35717 | 70475936 |
Muscle injury | 155.34 | 9.84 | 21 | 416770 | 38473 | 70473180 |
Vision blurred | 150.99 | 9.84 | 1016 | 415775 | 93968 | 70417685 |
Hepatic function abnormal | 149.07 | 9.84 | 109 | 416682 | 67887 | 70443766 |
Anxiety | 148.81 | 9.84 | 1962 | 414829 | 218368 | 70293285 |
Confusional state | 147.46 | 9.84 | 2419 | 414372 | 281979 | 70229674 |
Respiratory depression | 146.36 | 9.84 | 397 | 416394 | 24434 | 70487219 |
Cytomegalovirus infection | 146.28 | 9.84 | 28 | 416763 | 39730 | 70471923 |
Balance disorder | 146.24 | 9.84 | 969 | 415822 | 89159 | 70422494 |
Pain in extremity | 139.06 | 9.84 | 2703 | 414088 | 325379 | 70186274 |
Gait disturbance | 136.71 | 9.84 | 1676 | 415115 | 183430 | 70328223 |
Hypoaesthesia | 136.06 | 9.84 | 1442 | 415349 | 152297 | 70359356 |
Hypersensitivity | 134.58 | 9.84 | 795 | 415996 | 229017 | 70282636 |
Folliculitis | 133.26 | 9.84 | 42 | 416749 | 42528 | 70469125 |
Wound | 127.58 | 9.84 | 241 | 416550 | 98491 | 70413162 |
Cardio-respiratory arrest | 127.44 | 9.84 | 1020 | 415771 | 99657 | 70411996 |
Discomfort | 126.28 | 9.84 | 269 | 416522 | 105167 | 70406486 |
Thrombocytopenia | 124.72 | 9.84 | 857 | 415934 | 238253 | 70273400 |
Anaemia | 124.05 | 9.84 | 1648 | 415143 | 401775 | 70109878 |
Product dose omission issue | 119.13 | 9.84 | 1867 | 414924 | 215601 | 70296052 |
C-reactive protein abnormal | 119.10 | 9.84 | 39 | 416752 | 38540 | 70473113 |
Cardiac failure | 118.65 | 9.84 | 438 | 416353 | 143103 | 70368550 |
Sopor | 117.74 | 9.84 | 428 | 416363 | 30839 | 70480814 |
Therapeutic product effect decreased | 113.94 | 9.84 | 443 | 416348 | 142575 | 70369078 |
Migraine | 113.77 | 9.84 | 771 | 416020 | 71467 | 70440186 |
Lower respiratory tract infection | 112.39 | 9.84 | 313 | 416478 | 111600 | 70400053 |
Intentional product misuse | 96.71 | 9.84 | 799 | 415992 | 78796 | 70432857 |
Lethargy | 96.64 | 9.84 | 765 | 416026 | 74485 | 70437168 |
Mucosal inflammation | 94.52 | 9.84 | 158 | 416633 | 67692 | 70443961 |
Overdose | 93.57 | 9.84 | 1459 | 415332 | 168286 | 70343367 |
Neutropenia | 91.68 | 9.84 | 1017 | 415774 | 256139 | 70255514 |
Insomnia | 91.66 | 9.84 | 1793 | 414998 | 216013 | 70295640 |
Bone marrow failure | 89.92 | 9.84 | 93 | 416698 | 48917 | 70462736 |
Myelosuppression | 88.71 | 9.84 | 33 | 416758 | 30112 | 70481541 |
Sleep apnoea syndrome | 88.35 | 9.84 | 404 | 416387 | 32309 | 70479344 |
Drug resistance | 87.97 | 9.84 | 58 | 416733 | 38132 | 70473521 |
Paraesthesia | 86.03 | 9.84 | 1266 | 415525 | 144271 | 70367382 |
Product complaint | 84.93 | 9.84 | 208 | 416583 | 12023 | 70499630 |
Irritable bowel syndrome | 84.04 | 9.84 | 105 | 416686 | 50745 | 70460908 |
Dyskinesia | 80.04 | 9.84 | 463 | 416328 | 40611 | 70471042 |
Impaired healing | 79.99 | 9.84 | 201 | 416590 | 74173 | 70437480 |
Cardiac arrest | 79.95 | 9.84 | 1352 | 415439 | 158482 | 70353171 |
Burning sensation | 79.52 | 9.84 | 558 | 416233 | 52312 | 70459341 |
Inadequate analgesia | 77.68 | 9.84 | 108 | 416683 | 4014 | 70507639 |
Amnesia | 77.59 | 9.84 | 549 | 416242 | 51606 | 70460047 |
Multiple organ dysfunction syndrome | 76.01 | 9.84 | 353 | 416438 | 108162 | 70403491 |
Depressed level of consciousness | 74.01 | 9.84 | 813 | 415978 | 86618 | 70425035 |
Mood altered | 73.82 | 9.84 | 239 | 416552 | 16236 | 70495417 |
Nightmare | 73.28 | 9.84 | 291 | 416500 | 21865 | 70489788 |
Malignant neoplasm progression | 72.34 | 9.84 | 419 | 416372 | 121320 | 70390333 |
Serotonin syndrome | 72.08 | 9.84 | 459 | 416332 | 41655 | 70469998 |
Ataxia | 72.07 | 9.84 | 299 | 416492 | 22918 | 70488735 |
Pancytopenia | 71.79 | 9.84 | 556 | 416235 | 150551 | 70361102 |
Dysarthria | 71.71 | 9.84 | 618 | 416173 | 61695 | 70449958 |
Drug reaction with eosinophilia and systemic symptoms | 71.14 | 9.84 | 146 | 416645 | 57867 | 70453786 |
Septic shock | 70.71 | 9.84 | 379 | 416412 | 111879 | 70399774 |
Muscle twitching | 70.13 | 9.84 | 266 | 416525 | 19561 | 70492092 |
Urinary tract infection | 69.71 | 9.84 | 1935 | 414856 | 246834 | 70264819 |
Abdominal discomfort | 68.76 | 9.84 | 869 | 415922 | 213789 | 70297864 |
Drug use disorder | 68.01 | 9.84 | 149 | 416642 | 8002 | 70503651 |
Hypokalaemia | 67.45 | 9.84 | 472 | 416319 | 130716 | 70380937 |
Intervertebral disc degeneration | 67.19 | 9.84 | 207 | 416584 | 13693 | 70497960 |
Crying | 66.58 | 9.84 | 274 | 416517 | 20925 | 70490728 |
Mental disorder | 66.31 | 9.84 | 335 | 416456 | 27905 | 70483748 |
Treatment failure | 65.86 | 9.84 | 536 | 416255 | 143606 | 70368047 |
Stiff person syndrome | 65.61 | 9.84 | 35 | 416756 | 322 | 70511331 |
Hallucination, visual | 64.71 | 9.84 | 342 | 416449 | 28995 | 70482658 |
Swollen joint count increased | 64.50 | 9.84 | 4 | 416787 | 13696 | 70497957 |
Seizure | 63.12 | 9.84 | 1429 | 415362 | 176533 | 70335120 |
Hyperaesthesia | 62.54 | 9.84 | 173 | 416618 | 10769 | 70500884 |
Haemophagocytic lymphohistiocytosis | 62.01 | 9.84 | 19 | 416772 | 19593 | 70492060 |
Restless legs syndrome | 61.72 | 9.84 | 243 | 416548 | 18185 | 70493468 |
Atrial fibrillation | 61.41 | 9.84 | 740 | 416051 | 183608 | 70328045 |
Euphoric mood | 59.84 | 9.84 | 128 | 416663 | 6761 | 70504892 |
Off label use | 59.68 | 9.84 | 3668 | 413123 | 739392 | 69772261 |
Live birth | 59.36 | 9.84 | 6 | 416785 | 13773 | 70497880 |
Trigeminal neuralgia | 59.11 | 9.84 | 86 | 416705 | 3335 | 70508318 |
Melaena | 58.52 | 9.84 | 155 | 416636 | 56200 | 70455453 |
Premature delivery | 58.33 | 9.84 | 26 | 416765 | 21278 | 70490375 |
Muscular weakness | 58.21 | 9.84 | 1139 | 415652 | 137197 | 70374456 |
Unresponsive to stimuli | 58.17 | 9.84 | 512 | 416279 | 51419 | 70460234 |
Fatigue | 58.04 | 9.84 | 5608 | 411183 | 818711 | 69692942 |
Coordination abnormal | 57.20 | 9.84 | 216 | 416575 | 15850 | 70495803 |
Head injury | 57.13 | 9.84 | 370 | 416421 | 33771 | 70477882 |
Appendicolith | 56.98 | 9.84 | 112 | 416679 | 5568 | 70506085 |
Nervousness | 56.90 | 9.84 | 345 | 416446 | 30775 | 70480878 |
Therapeutic response unexpected | 56.75 | 9.84 | 235 | 416556 | 17996 | 70493657 |
Device expulsion | 56.58 | 9.84 | 30 | 416761 | 22216 | 70489437 |
Pneumocystis jirovecii pneumonia | 56.42 | 9.84 | 56 | 416735 | 30026 | 70481627 |
Spinal operation | 55.86 | 9.84 | 126 | 416665 | 6902 | 70504751 |
Ill-defined disorder | 55.76 | 9.84 | 152 | 416639 | 54589 | 70457064 |
Intentional product use issue | 55.69 | 9.84 | 445 | 416346 | 119697 | 70391956 |
Back disorder | 55.48 | 9.84 | 162 | 416629 | 10402 | 70501251 |
Rash | 55.24 | 9.84 | 2445 | 414346 | 508117 | 70003536 |
Alopecia | 54.80 | 9.84 | 828 | 415963 | 197662 | 70313991 |
Intervertebral disc protrusion | 54.71 | 9.84 | 261 | 416530 | 21242 | 70490411 |
Death | 54.43 | 9.84 | 3584 | 413207 | 506477 | 70005176 |
Speech disorder | 54.25 | 9.84 | 494 | 416297 | 50086 | 70461567 |
Right atrial hypertrophy | 54.19 | 9.84 | 38 | 416753 | 592 | 70511061 |
Back pain | 53.79 | 9.84 | 2024 | 414767 | 269128 | 70242525 |
Bradyphrenia | 53.66 | 9.84 | 154 | 416637 | 9792 | 70501861 |
Liver injury | 53.14 | 9.84 | 100 | 416691 | 40935 | 70470718 |
Hepatic failure | 52.90 | 9.84 | 168 | 416623 | 57457 | 70454196 |
Rheumatic fever | 52.53 | 9.84 | 19 | 416772 | 17641 | 70494012 |
Blood lactate dehydrogenase increased | 51.56 | 9.84 | 79 | 416712 | 35048 | 70476605 |
Bone erosion | 51.14 | 9.84 | 13 | 416778 | 15160 | 70496493 |
Pleural effusion | 50.72 | 9.84 | 517 | 416274 | 132347 | 70379306 |
Anticipatory anxiety | 50.54 | 9.84 | 44 | 416747 | 954 | 70510699 |
Infection | 50.38 | 9.84 | 903 | 415888 | 209882 | 70301771 |
Anger | 50.26 | 9.84 | 208 | 416583 | 15924 | 70495729 |
Poisoning | 50.09 | 9.84 | 264 | 416527 | 22358 | 70489295 |
Disseminated intravascular coagulation | 49.86 | 9.84 | 75 | 416716 | 33523 | 70478130 |
Renal impairment | 49.77 | 9.84 | 573 | 416218 | 143364 | 70368289 |
Pain | 49.00 | 9.84 | 4310 | 412481 | 624506 | 69887147 |
Feeling drunk | 48.60 | 9.84 | 90 | 416701 | 4277 | 70507376 |
Graft versus host disease | 48.51 | 9.84 | 14 | 416777 | 15009 | 70496644 |
Urinary incontinence | 48.18 | 9.84 | 384 | 416407 | 37458 | 70474195 |
Nasopharyngitis | 48.16 | 9.84 | 968 | 415823 | 221238 | 70290415 |
Presbyacusis | 48.07 | 9.84 | 68 | 416723 | 2569 | 70509084 |
Leukopenia | 47.87 | 9.84 | 398 | 416393 | 106162 | 70405491 |
Irritability | 47.64 | 9.84 | 386 | 416405 | 37839 | 70473814 |
Jaundice | 47.47 | 9.84 | 144 | 416647 | 49964 | 70461689 |
Colitis | 47.44 | 9.84 | 203 | 416588 | 63611 | 70448042 |
Anorgasmia | 47.37 | 9.84 | 44 | 416747 | 1041 | 70510612 |
Hypersomnia | 47.13 | 9.84 | 244 | 416547 | 20520 | 70491133 |
Asterixis | 45.90 | 9.84 | 64 | 416727 | 2385 | 70509268 |
Gait inability | 45.74 | 9.84 | 451 | 416340 | 46724 | 70464929 |
Eosinophilia | 45.69 | 9.84 | 106 | 416685 | 40213 | 70471440 |
Swelling | 45.59 | 9.84 | 806 | 415985 | 187733 | 70323920 |
Osteonecrosis of jaw | 45.50 | 9.84 | 109 | 416682 | 40893 | 70470760 |
Diabetic neuropathy | 45.42 | 9.84 | 104 | 416687 | 5754 | 70505899 |
Diplopia | 45.25 | 9.84 | 302 | 416489 | 27845 | 70483808 |
Rheumatoid nodule | 45.17 | 9.84 | 16 | 416775 | 15051 | 70496602 |
Hepatotoxicity | 44.90 | 9.84 | 122 | 416669 | 43864 | 70467789 |
Stomatitis | 44.66 | 9.84 | 511 | 416280 | 128000 | 70383653 |
Rash maculo-papular | 44.57 | 9.84 | 150 | 416641 | 50395 | 70461258 |
Post transplant lymphoproliferative disorder | 44.38 | 9.84 | 5 | 416786 | 10540 | 70501113 |
Myocardial stunning | 44.37 | 9.84 | 22 | 416769 | 171 | 70511482 |
Erythema | 44.25 | 9.84 | 866 | 415925 | 198697 | 70312956 |
Impaired driving ability | 44.23 | 9.84 | 92 | 416699 | 4765 | 70506888 |
Suspected suicide | 44.05 | 9.84 | 133 | 416658 | 8701 | 70502952 |
Red blood cell sedimentation rate abnormal | 43.54 | 9.84 | 30 | 416761 | 19273 | 70492380 |
Agitation | 43.48 | 9.84 | 781 | 416010 | 92594 | 70419059 |
Toxic epidermal necrolysis | 43.23 | 9.84 | 106 | 416685 | 39451 | 70472202 |
Anaphylactic shock | 43.11 | 9.84 | 78 | 416713 | 32412 | 70479241 |
Transplant rejection | 42.66 | 9.84 | 27 | 416764 | 18144 | 70493509 |
Somatic symptom disorder | 42.53 | 9.84 | 56 | 416735 | 1974 | 70509679 |
Transaminases increased | 42.51 | 9.84 | 138 | 416653 | 46880 | 70464773 |
Acute respiratory distress syndrome | 42.43 | 9.84 | 114 | 416677 | 41140 | 70470513 |
Acute myeloid leukaemia | 42.21 | 9.84 | 73 | 416718 | 30867 | 70480786 |
Delirium | 42.09 | 9.84 | 644 | 416147 | 73970 | 70437683 |
Disorientation | 42.07 | 9.84 | 523 | 416268 | 57400 | 70454253 |
Drug intolerance | 42.05 | 9.84 | 1007 | 415784 | 224680 | 70286973 |
Aspergillus infection | 41.34 | 9.84 | 27 | 416764 | 17841 | 70493812 |
Accidental poisoning | 41.05 | 9.84 | 49 | 416742 | 1561 | 70510092 |
Gait spastic | 41.04 | 9.84 | 40 | 416751 | 1007 | 70510646 |
Myokymia | 40.88 | 9.84 | 18 | 416773 | 103 | 70511550 |
Alanine aminotransferase increased | 40.77 | 9.84 | 615 | 416176 | 146865 | 70364788 |
Blister | 40.52 | 9.84 | 386 | 416405 | 100140 | 70411513 |
Venoocclusive liver disease | 40.40 | 9.84 | 7 | 416784 | 10671 | 70500982 |
Proteinuria | 40.35 | 9.84 | 69 | 416722 | 29305 | 70482348 |
Agranulocytosis | 40.22 | 9.84 | 113 | 416678 | 40185 | 70471468 |
Pleural thickening | 40.21 | 9.84 | 65 | 416726 | 2767 | 70508886 |
Hyperreflexia | 39.93 | 9.84 | 115 | 416676 | 7327 | 70504326 |
Nausea | 39.88 | 9.84 | 5648 | 411143 | 846440 | 69665213 |
Sinusitis | 39.42 | 9.84 | 728 | 416063 | 168467 | 70343186 |
Hyperhidrosis | 38.94 | 9.84 | 1031 | 415760 | 130555 | 70381098 |
Full blood count decreased | 38.67 | 9.84 | 257 | 416534 | 23661 | 70487992 |
Neutrophil count decreased | 38.48 | 9.84 | 310 | 416481 | 83246 | 70428407 |
Drug-induced liver injury | 38.42 | 9.84 | 184 | 416607 | 55929 | 70455724 |
Blood bilirubin increased | 38.40 | 9.84 | 201 | 416590 | 59700 | 70451953 |
Pleural fibrosis | 38.39 | 9.84 | 79 | 416712 | 4060 | 70507593 |
Bronchopulmonary aspergillosis | 38.36 | 9.84 | 40 | 416751 | 20962 | 70490691 |
Lymphoedema | 37.99 | 9.84 | 148 | 416643 | 11021 | 70500632 |
Neck pain | 37.47 | 9.84 | 575 | 416216 | 66082 | 70445571 |
Influenza like illness | 36.51 | 9.84 | 563 | 416228 | 64768 | 70446885 |
Epistaxis | 36.47 | 9.84 | 406 | 416385 | 102221 | 70409432 |
Psoriatic arthropathy | 36.32 | 9.84 | 227 | 416564 | 64544 | 70447109 |
Shock haemorrhagic | 35.96 | 9.84 | 32 | 416759 | 18074 | 70493579 |
Therapeutic response decreased | 35.89 | 9.84 | 199 | 416592 | 58254 | 70453399 |
Cytomegalovirus viraemia | 35.74 | 9.84 | 12 | 416779 | 11673 | 70499980 |
Posterior reversible encephalopathy syndrome | 35.70 | 9.84 | 55 | 416736 | 24347 | 70487306 |
Constipation | 35.53 | 9.84 | 1819 | 414972 | 250619 | 70261034 |
Haematotoxicity | 35.43 | 9.84 | 18 | 416773 | 13656 | 70497997 |
Relapsing-remitting multiple sclerosis | 35.36 | 9.84 | 42 | 416749 | 1331 | 70510322 |
Mental impairment | 35.25 | 9.84 | 197 | 416594 | 17058 | 70494595 |
Joint injury | 35.22 | 9.84 | 275 | 416516 | 26657 | 70484996 |
Disturbance in attention | 34.98 | 9.84 | 396 | 416395 | 42498 | 70469155 |
Dry mouth | 34.83 | 9.84 | 595 | 416196 | 69862 | 70441791 |
Colitis ulcerative | 33.95 | 9.84 | 95 | 416696 | 33828 | 70477825 |
Injection site mass | 33.94 | 9.84 | 204 | 416587 | 18139 | 70493514 |
Blood magnesium increased | 33.80 | 9.84 | 66 | 416725 | 3265 | 70508388 |
Right ventricular hypertrophy | 33.75 | 9.84 | 42 | 416749 | 1398 | 70510255 |
Thrombotic microangiopathy | 33.73 | 9.84 | 33 | 416758 | 17815 | 70493838 |
Complex regional pain syndrome | 33.68 | 9.84 | 47 | 416744 | 1753 | 70509900 |
Prostate cancer | 33.67 | 9.84 | 84 | 416707 | 31079 | 70480574 |
Needle fatigue | 33.43 | 9.84 | 31 | 416760 | 732 | 70510921 |
Epstein-Barr virus infection | 33.27 | 9.84 | 18 | 416773 | 13180 | 70498473 |
Headache | 33.16 | 9.84 | 3895 | 412896 | 576510 | 69935143 |
Paranoia | 33.10 | 9.84 | 194 | 416597 | 17094 | 70494559 |
Schizophrenia | 32.86 | 9.84 | 30 | 416761 | 16738 | 70494915 |
Panniculitis | 32.59 | 9.84 | 11 | 416780 | 10665 | 70500988 |
Ankle fracture | 32.56 | 9.84 | 177 | 416614 | 15167 | 70496486 |
Hypermobility syndrome | 32.20 | 9.84 | 26 | 416765 | 506 | 70511147 |
Cholangitis | 31.77 | 9.84 | 14 | 416777 | 11535 | 70500118 |
Somatic delusion | 31.75 | 9.84 | 29 | 416762 | 671 | 70510982 |
Neutropenic sepsis | 31.72 | 9.84 | 61 | 416730 | 24769 | 70486884 |
Cystitis haemorrhagic | 31.72 | 9.84 | 6 | 416785 | 8587 | 70503066 |
Vertigo | 31.33 | 9.84 | 530 | 416261 | 62113 | 70449540 |
Dysstasia | 31.24 | 9.84 | 254 | 416537 | 24925 | 70486728 |
Neovascularisation | 31.11 | 9.84 | 36 | 416755 | 1109 | 70510544 |
Cholestasis | 31.04 | 9.84 | 160 | 416631 | 47712 | 70463941 |
Muscle tightness | 30.82 | 9.84 | 144 | 416647 | 11618 | 70500035 |
Surgery | 30.70 | 9.84 | 290 | 416501 | 29699 | 70481954 |
Labelled drug-drug interaction medication error | 30.19 | 9.84 | 60 | 416731 | 24067 | 70487586 |
Cerebral haemorrhage | 30.08 | 9.84 | 189 | 416602 | 53675 | 70457978 |
Lupus-like syndrome | 30.07 | 9.84 | 15 | 416776 | 11500 | 70500153 |
Cerebral infarction | 30.05 | 9.84 | 140 | 416651 | 42869 | 70468784 |
Pulmonary tuberculosis | 29.99 | 9.84 | 5 | 416786 | 7840 | 70503813 |
Tubulointerstitial nephritis | 29.96 | 9.84 | 97 | 416694 | 32979 | 70478674 |
Gastrointestinal haemorrhage | 29.93 | 9.84 | 598 | 416193 | 136810 | 70374843 |
Pregnancy | 29.88 | 9.84 | 59 | 416732 | 23722 | 70487931 |
Pulmonary toxicity | 29.85 | 9.84 | 13 | 416778 | 10785 | 70500868 |
Gamma-glutamyltransferase increased | 29.80 | 9.84 | 175 | 416616 | 50510 | 70461143 |
Victim of child abuse | 29.80 | 9.84 | 32 | 416759 | 906 | 70510747 |
Central nervous system lesion | 29.43 | 9.84 | 148 | 416643 | 12305 | 70499348 |
Limb injury | 29.41 | 9.84 | 255 | 416536 | 25497 | 70486156 |
Gastrointestinal disorder | 29.35 | 9.84 | 439 | 416352 | 104988 | 70406665 |
Autonomic nervous system imbalance | 29.29 | 9.84 | 73 | 416718 | 4266 | 70507387 |
Nerve injury | 28.88 | 9.84 | 111 | 416680 | 8213 | 70503440 |
Therapy non-responder | 28.64 | 9.84 | 301 | 416490 | 76614 | 70435039 |
Tuberculosis | 28.59 | 9.84 | 27 | 416764 | 14821 | 70496832 |
Drug eruption | 28.53 | 9.84 | 127 | 416664 | 39369 | 70472284 |
Product use issue | 28.45 | 9.84 | 822 | 415969 | 179115 | 70332538 |
Quality of life decreased | 28.43 | 9.84 | 112 | 416679 | 8383 | 70503270 |
Incoherent | 28.34 | 9.84 | 101 | 416690 | 7205 | 70504448 |
Hostility | 28.33 | 9.84 | 49 | 416742 | 2206 | 70509447 |
Nerve compression | 28.33 | 9.84 | 109 | 416682 | 8069 | 70503584 |
Thinking abnormal | 28.32 | 9.84 | 143 | 416648 | 11908 | 70499745 |
Hepatocellular injury | 28.25 | 9.84 | 157 | 416634 | 45934 | 70465719 |
Acute kidney injury | 28.22 | 9.84 | 2403 | 414388 | 472221 | 70039432 |
Pathogen resistance | 28.18 | 9.84 | 22 | 416769 | 13257 | 70498396 |
Pulmonary fibrosis | 28.12 | 9.84 | 105 | 416686 | 34205 | 70477448 |
Acute hepatic failure | 28.06 | 9.84 | 77 | 416714 | 27595 | 70484058 |
Drug abuser | 28.04 | 9.84 | 87 | 416704 | 5777 | 70505876 |
Therapy cessation | 27.96 | 9.84 | 312 | 416479 | 33364 | 70478289 |
Tumour lysis syndrome | 27.70 | 9.84 | 52 | 416739 | 21308 | 70490345 |
Pituitary tumour benign | 27.48 | 9.84 | 51 | 416740 | 2428 | 70509225 |
Panic attack | 27.37 | 9.84 | 223 | 416568 | 21896 | 70489757 |
Drug screen positive | 27.33 | 9.84 | 86 | 416705 | 5754 | 70505899 |
Dyspnoea | 27.26 | 9.84 | 4040 | 412751 | 766020 | 69745633 |
Metabolic encephalopathy | 26.98 | 9.84 | 109 | 416682 | 8254 | 70503399 |
Haemoglobin decreased | 26.98 | 9.84 | 960 | 415831 | 204199 | 70307454 |
Bronchial wall thickening | 26.92 | 9.84 | 47 | 416744 | 2132 | 70509521 |
Coma | 26.70 | 9.84 | 718 | 416073 | 91126 | 70420527 |
Skin necrosis | 26.54 | 9.84 | 34 | 416757 | 16257 | 70495396 |
Erectile dysfunction | 26.49 | 9.84 | 153 | 416638 | 13409 | 70498244 |
Blood parathyroid hormone decreased | 26.35 | 9.84 | 10 | 416781 | 9014 | 70502639 |
Metastases to liver | 26.24 | 9.84 | 72 | 416719 | 25806 | 70485847 |
Parasomnia | 26.14 | 9.84 | 23 | 416768 | 506 | 70511147 |
Obsessive-compulsive disorder | 25.98 | 9.84 | 80 | 416711 | 5290 | 70506363 |
Myocarditis | 25.95 | 9.84 | 44 | 416747 | 18749 | 70492904 |
Acute coronary syndrome | 25.94 | 9.84 | 49 | 416742 | 20030 | 70491623 |
Hypertonic bladder | 25.91 | 9.84 | 64 | 416727 | 3719 | 70507934 |
Pneumonitis | 25.86 | 9.84 | 201 | 416590 | 54396 | 70457257 |
Circulatory collapse | 25.66 | 9.84 | 114 | 416677 | 35360 | 70476293 |
Asthenia | 25.53 | 9.84 | 3067 | 413724 | 454599 | 70057054 |
Angioedema | 25.48 | 9.84 | 259 | 416532 | 66351 | 70445302 |
Hip fracture | 25.39 | 9.84 | 266 | 416525 | 27997 | 70483656 |
Dysphemia | 25.38 | 9.84 | 58 | 416733 | 3205 | 70508448 |
Therapeutic product effect variable | 25.31 | 9.84 | 40 | 416751 | 1670 | 70509983 |
Muscle spasticity | 25.17 | 9.84 | 200 | 416591 | 19489 | 70492164 |
Transplant dysfunction | 25.13 | 9.84 | 5 | 416786 | 6904 | 70504749 |
Hypomagnesaemia | 24.90 | 9.84 | 139 | 416652 | 40625 | 70471028 |
Arthralgia | 24.88 | 9.84 | 2584 | 414207 | 500806 | 70010847 |
Enterocolitis | 24.87 | 9.84 | 24 | 416767 | 13042 | 70498611 |
Facial pain | 24.73 | 9.84 | 105 | 416686 | 8131 | 70503522 |
Radiculopathy | 24.69 | 9.84 | 85 | 416706 | 5960 | 70505693 |
Haemolysis | 24.69 | 9.84 | 19 | 416772 | 11532 | 70500121 |
Focal dyscognitive seizures | 24.68 | 9.84 | 59 | 416732 | 3358 | 70508295 |
Acute myocardial infarction | 24.47 | 9.84 | 292 | 416499 | 72595 | 70439058 |
Chronic graft versus host disease | 24.41 | 9.84 | 5 | 416786 | 6765 | 70504888 |
Acute graft versus host disease in skin | 24.27 | 9.84 | 6 | 416785 | 7131 | 70504522 |
Drug effective for unapproved indication | 24.27 | 9.84 | 71 | 416720 | 4564 | 70507089 |
Pollakiuria | 24.24 | 9.84 | 302 | 416489 | 33159 | 70478494 |
Unintentional medical device removal | 24.21 | 9.84 | 6 | 416785 | 7118 | 70504535 |
Device use error | 24.03 | 9.84 | 5 | 416786 | 6691 | 70504962 |
Epigastric discomfort | 23.92 | 9.84 | 95 | 416696 | 7138 | 70504515 |
Colorectal cancer | 23.73 | 9.84 | 10 | 416781 | 8460 | 70503193 |
Spinal osteoarthritis | 23.67 | 9.84 | 163 | 416628 | 15185 | 70496468 |
Micturition urgency | 23.66 | 9.84 | 130 | 416661 | 11184 | 70500469 |
Bipolar disorder | 23.63 | 9.84 | 98 | 416693 | 7510 | 70504143 |
Exposure via ingestion | 23.57 | 9.84 | 73 | 416718 | 4842 | 70506811 |
Pulmonary function test abnormal | 23.52 | 9.84 | 58 | 416733 | 3367 | 70508286 |
Peritonitis | 23.49 | 9.84 | 77 | 416714 | 26082 | 70485571 |
Cellulitis | 23.46 | 9.84 | 754 | 416037 | 98174 | 70413479 |
Bradypnoea | 23.39 | 9.84 | 78 | 416713 | 5381 | 70506272 |
Cyst | 23.25 | 9.84 | 141 | 416650 | 12578 | 70499075 |
Cardiac failure acute | 23.18 | 9.84 | 42 | 416749 | 17445 | 70494208 |
Knee arthroplasty | 23.18 | 9.84 | 113 | 416678 | 34188 | 70477465 |
Appendicitis | 23.08 | 9.84 | 173 | 416618 | 16560 | 70495093 |
Intentional self-injury | 23.07 | 9.84 | 286 | 416505 | 31364 | 70480289 |
Rib fracture | 22.94 | 9.84 | 239 | 416552 | 25117 | 70486536 |
Device adhesion issue | 22.88 | 9.84 | 4 | 416787 | 6059 | 70505594 |
Febrile bone marrow aplasia | 22.86 | 9.84 | 22 | 416769 | 11969 | 70499684 |
Lactic acidosis | 22.79 | 9.84 | 258 | 416533 | 64766 | 70446887 |
Limb discomfort | 22.77 | 9.84 | 271 | 416520 | 29434 | 70482219 |
Encephalopathy | 22.74 | 9.84 | 498 | 416293 | 61163 | 70450490 |
Hyperbilirubinaemia | 22.73 | 9.84 | 63 | 416728 | 22505 | 70489148 |
Cognitive disorder | 22.70 | 9.84 | 493 | 416298 | 60463 | 70451190 |
Gestational diabetes | 22.56 | 9.84 | 4 | 416787 | 5997 | 70505656 |
Disorganised speech | 22.45 | 9.84 | 39 | 416752 | 1762 | 70509891 |
Congenital multiplex arthrogryposis | 22.45 | 9.84 | 7 | 416784 | 11 | 70511642 |
Blood creatine phosphokinase increased | 22.30 | 9.84 | 241 | 416550 | 61022 | 70450631 |
Hip arthroplasty | 22.22 | 9.84 | 87 | 416704 | 27953 | 70483700 |
Complications of transplanted kidney | 22.21 | 9.84 | 4 | 416787 | 5930 | 70505723 |
Concussion | 22.17 | 9.84 | 104 | 416687 | 8405 | 70503248 |
Toxic skin eruption | 22.05 | 9.84 | 54 | 416737 | 20108 | 70491545 |
Palmar-plantar erythrodysaesthesia syndrome | 22.00 | 9.84 | 97 | 416694 | 30150 | 70481503 |
Bone density decreased | 21.93 | 9.84 | 21 | 416770 | 11453 | 70500200 |
Pre-existing condition improved | 21.90 | 9.84 | 72 | 416719 | 4930 | 70506723 |
Herpes zoster | 21.90 | 9.84 | 656 | 416135 | 84579 | 70427074 |
Visual impairment | 21.81 | 9.84 | 622 | 416169 | 79628 | 70432025 |
Slow speech | 21.72 | 9.84 | 43 | 416748 | 2149 | 70509504 |
Premature labour | 21.53 | 9.84 | 10 | 416781 | 7990 | 70503663 |
Hepatitis fulminant | 21.49 | 9.84 | 6 | 416785 | 6575 | 70505078 |
Pseudomonas infection | 21.47 | 9.84 | 50 | 416741 | 18944 | 70492709 |
Foot fracture | 21.30 | 9.84 | 192 | 416599 | 19408 | 70492245 |
Alcoholism | 21.30 | 9.84 | 66 | 416725 | 4379 | 70507274 |
Rales | 21.11 | 9.84 | 43 | 416748 | 17092 | 70494561 |
Blood pressure increased | 21.09 | 9.84 | 899 | 415892 | 187618 | 70324035 |
Nephrotic syndrome | 20.89 | 9.84 | 19 | 416772 | 10621 | 70501032 |
Visual snow syndrome | 20.85 | 9.84 | 8 | 416783 | 30 | 70511623 |
Hypertension | 20.81 | 9.84 | 1478 | 415313 | 294555 | 70217098 |
Inflammation | 20.72 | 9.84 | 331 | 416460 | 78334 | 70433319 |
Conversion disorder | 20.69 | 9.84 | 37 | 416754 | 1711 | 70509942 |
Dermatitis exfoliative generalised | 20.67 | 9.84 | 6 | 416785 | 6408 | 70505245 |
Device difficult to use | 20.57 | 9.84 | 20 | 416771 | 10829 | 70500824 |
Oesophageal carcinoma | 20.54 | 9.84 | 15 | 416776 | 9351 | 70502302 |
Hepatitis | 20.53 | 9.84 | 191 | 416600 | 49789 | 70461864 |
Stress | 20.52 | 9.84 | 534 | 416257 | 67432 | 70444221 |
Alanine aminotransferase abnormal | 20.30 | 9.84 | 11 | 416780 | 8048 | 70503605 |
Analgesic drug level above therapeutic | 20.27 | 9.84 | 19 | 416772 | 455 | 70511198 |
Deafness neurosensory | 20.26 | 9.84 | 85 | 416706 | 6547 | 70505106 |
Renal failure | 20.25 | 9.84 | 906 | 415885 | 188164 | 70323489 |
Lung disorder | 20.15 | 9.84 | 287 | 416504 | 69197 | 70442456 |
Neutropenic colitis | 20.14 | 9.84 | 3 | 416788 | 5111 | 70506542 |
Gastric cancer | 20.09 | 9.84 | 14 | 416777 | 8941 | 70502712 |
Stevens-Johnson syndrome | 20.05 | 9.84 | 126 | 416665 | 35781 | 70475872 |
Shock | 20.01 | 9.84 | 147 | 416644 | 40278 | 70471375 |
Drug tolerance decreased | 19.98 | 9.84 | 17 | 416774 | 9816 | 70501837 |
Ischaemic stroke | 19.98 | 9.84 | 103 | 416688 | 30717 | 70480936 |
Tooth loss | 19.96 | 9.84 | 83 | 416708 | 6367 | 70505286 |
Sacroiliitis | 19.96 | 9.84 | 53 | 416738 | 3220 | 70508433 |
Endophthalmitis | 19.88 | 9.84 | 6 | 416785 | 6249 | 70505404 |
Aspartate aminotransferase increased | 19.83 | 9.84 | 581 | 416210 | 126397 | 70385256 |
Blood cholesterol increased | 19.75 | 9.84 | 264 | 416527 | 64340 | 70447313 |
Developmental hip dysplasia | 19.60 | 9.84 | 13 | 416778 | 184 | 70511469 |
Sweat gland disorder | 19.60 | 9.84 | 13 | 416778 | 184 | 70511469 |
Blood pressure fluctuation | 19.58 | 9.84 | 237 | 416554 | 58775 | 70452878 |
Haematochezia | 19.42 | 9.84 | 307 | 416484 | 72774 | 70438879 |
Oesophageal spasm | 19.40 | 9.84 | 51 | 416740 | 3080 | 70508573 |
Haemorrhage | 19.39 | 9.84 | 361 | 416430 | 83454 | 70428199 |
Uveitis | 19.37 | 9.84 | 36 | 416755 | 14809 | 70496844 |
Skin toxicity | 19.37 | 9.84 | 9 | 416782 | 7189 | 70504464 |
Psychotic disorder due to a general medical condition | 19.33 | 9.84 | 15 | 416776 | 275 | 70511378 |
Decreased interest | 19.27 | 9.84 | 54 | 416737 | 3387 | 70508266 |
Antidepressant drug level above therapeutic | 19.23 | 9.84 | 21 | 416770 | 606 | 70511047 |
Cough | 19.21 | 9.84 | 1648 | 415143 | 323729 | 70187924 |
Metabolic acidosis | 19.19 | 9.84 | 314 | 416477 | 74032 | 70437621 |
Duodenal ulcer | 19.12 | 9.84 | 38 | 416753 | 15242 | 70496411 |
Dysphoria | 19.03 | 9.84 | 64 | 416727 | 4434 | 70507219 |
Haematuria | 18.99 | 9.84 | 261 | 416530 | 63312 | 70448341 |
Breakthrough pain | 18.85 | 9.84 | 30 | 416761 | 1260 | 70510393 |
Hyperuricaemia | 18.80 | 9.84 | 22 | 416769 | 10944 | 70500709 |
Delirium tremens | 18.75 | 9.84 | 22 | 416769 | 688 | 70510965 |
Ejection fraction decreased | 18.73 | 9.84 | 105 | 416686 | 30657 | 70480996 |
Violence-related symptom | 18.70 | 9.84 | 22 | 416769 | 690 | 70510963 |
Graft versus host disease in skin | 18.64 | 9.84 | 5 | 416786 | 5625 | 70506028 |
Granuloma skin | 18.61 | 9.84 | 11 | 416780 | 7671 | 70503982 |
Subileus | 18.56 | 9.84 | 4 | 416787 | 5223 | 70506430 |
Loss of consciousness | 18.53 | 9.84 | 1105 | 415686 | 154611 | 70357042 |
Chorea | 18.50 | 9.84 | 39 | 416752 | 2039 | 70509614 |
Allodynia | 18.47 | 9.84 | 31 | 416760 | 1362 | 70510291 |
Rib deformity | 18.45 | 9.84 | 12 | 416779 | 164 | 70511489 |
Nephropathy toxic | 18.41 | 9.84 | 52 | 416739 | 18462 | 70493191 |
Skin reaction | 18.40 | 9.84 | 34 | 416757 | 14015 | 70497638 |
Phantom limb syndrome | 18.30 | 9.84 | 16 | 416775 | 349 | 70511304 |
Psychomotor hyperactivity | 18.24 | 9.84 | 154 | 416637 | 15279 | 70496374 |
Binocular eye movement disorder | 18.21 | 9.84 | 10 | 416781 | 98 | 70511555 |
Diffuse axonal injury | 18.21 | 9.84 | 10 | 416781 | 98 | 70511555 |
Depressed mood | 18.15 | 9.84 | 360 | 416431 | 43460 | 70468193 |
Tardive dyskinesia | 18.10 | 9.84 | 110 | 416681 | 9819 | 70501834 |
Creatinine renal clearance decreased | 18.09 | 9.84 | 47 | 416744 | 17153 | 70494500 |
Tinnitus | 18.06 | 9.84 | 306 | 416485 | 35870 | 70475783 |
Body height decreased | 18.04 | 9.84 | 92 | 416699 | 7691 | 70503962 |
Blood pressure systolic abnormal | 18.03 | 9.84 | 30 | 416761 | 12879 | 70498774 |
Epidural lipomatosis | 17.92 | 9.84 | 25 | 416766 | 932 | 70510721 |
Eosinophilic colitis | 17.90 | 9.84 | 17 | 416774 | 414 | 70511239 |
Disease progression | 17.76 | 9.84 | 746 | 416045 | 155926 | 70355727 |
Osteosclerosis | 17.74 | 9.84 | 55 | 416736 | 3650 | 70508003 |
Adenovirus infection | 17.62 | 9.84 | 12 | 416779 | 7756 | 70503897 |
Diffuse large B-cell lymphoma | 17.59 | 9.84 | 32 | 416759 | 13270 | 70498383 |
Autoimmune haemolytic anaemia | 17.52 | 9.84 | 12 | 416779 | 7734 | 70503919 |
Pruritus | 17.43 | 9.84 | 1771 | 415020 | 343789 | 70167864 |
Breast cancer stage I | 17.42 | 9.84 | 7 | 416784 | 6095 | 70505558 |
Myelodysplastic syndrome | 17.42 | 9.84 | 103 | 416688 | 29682 | 70481971 |
Cytokine release syndrome | 17.42 | 9.84 | 88 | 416703 | 26379 | 70485274 |
Obstruction | 17.39 | 9.84 | 54 | 416737 | 3587 | 70508066 |
Ear deformity acquired | 17.28 | 9.84 | 5 | 416786 | 5 | 70511648 |
Atrioventricular block | 17.25 | 9.84 | 30 | 416761 | 12658 | 70498995 |
Micrognathia | 17.16 | 9.84 | 6 | 416785 | 16 | 70511637 |
Fibromyalgia | 17.13 | 9.84 | 385 | 416406 | 47489 | 70464164 |
Bone cyst | 16.98 | 9.84 | 46 | 416745 | 2828 | 70508825 |
Condition aggravated | 16.89 | 9.84 | 2228 | 414563 | 425407 | 70086246 |
Sensory disturbance | 16.87 | 9.84 | 139 | 416652 | 13693 | 70497960 |
Arteriovenous malformation | 16.84 | 9.84 | 33 | 416758 | 1637 | 70510016 |
Bladder cancer | 16.73 | 9.84 | 49 | 416742 | 17193 | 70494460 |
Idiopathic neutropenia | 16.57 | 9.84 | 4 | 416787 | 0 | 70511653 |
Tachycardia | 16.52 | 9.84 | 762 | 416029 | 157784 | 70353869 |
Sports injury | 16.45 | 9.84 | 11 | 416780 | 158 | 70511495 |
Affective disorder | 16.36 | 9.84 | 87 | 416704 | 7392 | 70504261 |
Pneumonia bacterial | 16.36 | 9.84 | 47 | 416744 | 16594 | 70495059 |
Injection site induration | 16.35 | 9.84 | 101 | 416690 | 9067 | 70502586 |
Bradycardia | 16.17 | 9.84 | 584 | 416207 | 124031 | 70387622 |
Spinal stenosis | 16.16 | 9.84 | 144 | 416647 | 14509 | 70497144 |
Hyperthyroidism | 16.13 | 9.84 | 62 | 416729 | 20029 | 70491624 |
Progressive multiple sclerosis | 16.10 | 9.84 | 22 | 416769 | 804 | 70510849 |
Blood pressure systolic increased | 16.08 | 9.84 | 238 | 416553 | 57021 | 70454632 |
Cervical spinal stenosis | 16.08 | 9.84 | 37 | 416754 | 2054 | 70509599 |
Mouth ulceration | 16.01 | 9.84 | 127 | 416664 | 34222 | 70477431 |
Kidney transplant rejection | 16.01 | 9.84 | 21 | 416770 | 9940 | 70501713 |
Hypoxic-ischaemic encephalopathy | 15.98 | 9.84 | 85 | 416706 | 7223 | 70504430 |
Post herpetic neuralgia | 15.94 | 9.84 | 41 | 416750 | 2443 | 70509210 |
Drug tolerance increased | 15.90 | 9.84 | 19 | 416772 | 606 | 70511047 |
Respiratory disorder | 15.86 | 9.84 | 150 | 416641 | 38973 | 70472680 |
Dependence | 15.85 | 9.84 | 39 | 416752 | 2261 | 70509392 |
Lumbar radiculopathy | 15.83 | 9.84 | 35 | 416756 | 1891 | 70509762 |
Nephrogenic systemic fibrosis | 15.79 | 9.84 | 74 | 416717 | 5978 | 70505675 |
Deprescribing error | 15.74 | 9.84 | 6 | 416785 | 22 | 70511631 |
Aggression | 15.61 | 9.84 | 384 | 416407 | 48062 | 70463591 |
Ascites | 15.60 | 9.84 | 291 | 416500 | 67256 | 70444397 |
Product communication issue | 15.55 | 9.84 | 21 | 416770 | 759 | 70510894 |
Colitis microscopic | 15.51 | 9.84 | 18 | 416773 | 8987 | 70502666 |
Myoclonic epilepsy | 15.47 | 9.84 | 34 | 416757 | 1830 | 70509823 |
Tendonitis | 15.46 | 9.84 | 72 | 416719 | 22050 | 70489603 |
Cystitis | 15.41 | 9.84 | 373 | 416418 | 46568 | 70465085 |
Long QT syndrome | 15.39 | 9.84 | 6 | 416785 | 5321 | 70506332 |
Urinary retention | 15.38 | 9.84 | 411 | 416380 | 52109 | 70459544 |
Dry eye | 15.37 | 9.84 | 271 | 416520 | 32011 | 70479642 |
Abnormal behaviour | 15.34 | 9.84 | 288 | 416503 | 34421 | 70477232 |
Brief psychotic disorder with marked stressors | 15.20 | 9.84 | 13 | 416778 | 275 | 70511378 |
Anal abscess | 15.17 | 9.84 | 16 | 416775 | 8342 | 70503311 |
Encephalitis | 15.16 | 9.84 | 36 | 416755 | 13549 | 70498104 |
Hypokinesia | 15.16 | 9.84 | 163 | 416628 | 17269 | 70494384 |
Sensory loss | 15.15 | 9.84 | 117 | 416674 | 11302 | 70500351 |
Snoring | 15.10 | 9.84 | 63 | 416728 | 4841 | 70506812 |
Carpal tunnel syndrome | 15.07 | 9.84 | 160 | 416631 | 16897 | 70494756 |
Platelet count decreased | 15.05 | 9.84 | 875 | 415916 | 177347 | 70334306 |
Radiation necrosis | 15.03 | 9.84 | 15 | 416776 | 389 | 70511264 |
Lip oedema | 15.00 | 9.84 | 7 | 416784 | 5576 | 70506077 |
Congenital neuropathy | 14.96 | 9.84 | 5 | 416786 | 11 | 70511642 |
Urine amphetamine positive | 14.96 | 9.84 | 8 | 416783 | 74 | 70511579 |
Varicella zoster virus infection | 14.95 | 9.84 | 3 | 416788 | 4117 | 70507536 |
Mucormycosis | 14.93 | 9.84 | 15 | 416776 | 7999 | 70503654 |
Osteopenia | 14.93 | 9.84 | 157 | 416634 | 16540 | 70495113 |
Persistent depressive disorder | 14.93 | 9.84 | 24 | 416767 | 1017 | 70510636 |
Aphasia | 14.91 | 9.84 | 346 | 416445 | 42903 | 70468750 |
Head banging | 14.89 | 9.84 | 17 | 416774 | 516 | 70511137 |
Drug screen negative | 14.89 | 9.84 | 13 | 416778 | 283 | 70511370 |
Arthrofibrosis | 14.76 | 9.84 | 9 | 416782 | 109 | 70511544 |
Abortion spontaneous | 14.74 | 9.84 | 93 | 416698 | 26386 | 70485267 |
Pre-eclampsia | 14.73 | 9.84 | 10 | 416781 | 6475 | 70505178 |
Large intestine perforation | 14.70 | 9.84 | 35 | 416756 | 13160 | 70498493 |
Alcohol withdrawal syndrome | 14.62 | 9.84 | 33 | 416758 | 1808 | 70509845 |
Myofascial pain syndrome | 14.61 | 9.84 | 33 | 416758 | 1809 | 70509844 |
Laboratory test abnormal | 14.60 | 9.84 | 223 | 416568 | 25600 | 70486053 |
Paranasal cyst | 14.60 | 9.84 | 15 | 416776 | 403 | 70511250 |
Teeth brittle | 14.59 | 9.84 | 16 | 416775 | 464 | 70511189 |
Antipsychotic drug level below therapeutic | 14.52 | 9.84 | 23 | 416768 | 962 | 70510691 |
Atonic urinary bladder | 14.51 | 9.84 | 8 | 416783 | 79 | 70511574 |
Rectal haemorrhage | 14.47 | 9.84 | 286 | 416505 | 65545 | 70446108 |
Red blood cell sedimentation rate increased | 14.47 | 9.84 | 151 | 416640 | 38491 | 70473162 |
Blood pressure decreased | 14.47 | 9.84 | 418 | 416373 | 91097 | 70420556 |
Self-medication | 14.41 | 9.84 | 58 | 416733 | 4385 | 70507268 |
Respiratory rate decreased | 14.38 | 9.84 | 61 | 416730 | 4721 | 70506932 |
Accidental exposure to product | 14.37 | 9.84 | 101 | 416690 | 27950 | 70483703 |
Hypothyroidism | 14.34 | 9.84 | 186 | 416605 | 45569 | 70466084 |
Liver disorder | 14.30 | 9.84 | 265 | 416526 | 61303 | 70450350 |
Movement disorder | 14.28 | 9.84 | 210 | 416581 | 23919 | 70487734 |
Somnambulism | 14.23 | 9.84 | 65 | 416726 | 5195 | 70506458 |
Fear of injection | 14.23 | 9.84 | 11 | 416780 | 6661 | 70504992 |
Hot flush | 14.23 | 9.84 | 387 | 416404 | 49197 | 70462456 |
Facial spasm | 14.21 | 9.84 | 19 | 416772 | 680 | 70510973 |
Neurogenic bladder | 14.19 | 9.84 | 52 | 416739 | 3761 | 70507892 |
Pericardial effusion | 14.16 | 9.84 | 167 | 416624 | 41609 | 70470044 |
Product physical issue | 14.11 | 9.84 | 51 | 416740 | 3663 | 70507990 |
Polyarthritis | 14.11 | 9.84 | 26 | 416765 | 10730 | 70500923 |
Post laminectomy syndrome | 14.02 | 9.84 | 13 | 416778 | 307 | 70511346 |
Hepatocellular carcinoma | 14.00 | 9.84 | 24 | 416767 | 10184 | 70501469 |
Postmortem blood drug level increased | 13.99 | 9.84 | 20 | 416771 | 763 | 70510890 |
Asthma | 13.93 | 9.84 | 574 | 416217 | 120219 | 70391434 |
Hypercalcaemia | 13.86 | 9.84 | 132 | 416659 | 34253 | 70477400 |
Acute pulmonary oedema | 13.84 | 9.84 | 37 | 416754 | 13375 | 70498278 |
Lymphoproliferative disorder | 13.83 | 9.84 | 7 | 416784 | 5322 | 70506331 |
Abnormal sleep-related event | 13.82 | 9.84 | 21 | 416770 | 847 | 70510806 |
Secondary progressive multiple sclerosis | 13.77 | 9.84 | 27 | 416764 | 1340 | 70510313 |
Cerebral disorder | 13.69 | 9.84 | 62 | 416729 | 4937 | 70506716 |
Cytomegalovirus chorioretinitis | 13.69 | 9.84 | 7 | 416784 | 5291 | 70506362 |
Spinal cord injury | 13.68 | 9.84 | 23 | 416768 | 1012 | 70510641 |
Product use in unapproved indication | 13.68 | 9.84 | 1406 | 415385 | 206072 | 70305581 |
Drug diversion | 13.60 | 9.84 | 25 | 416766 | 1181 | 70510472 |
Lumbar spinal stenosis | 13.57 | 9.84 | 61 | 416730 | 4842 | 70506811 |
Asphyxia | 13.57 | 9.84 | 25 | 416766 | 10317 | 70501336 |
Substance use | 13.57 | 9.84 | 19 | 416772 | 711 | 70510942 |
Cytomegalovirus colitis | 13.53 | 9.84 | 4 | 416787 | 4222 | 70507431 |
Inflammatory marker increased | 13.47 | 9.84 | 21 | 416770 | 9253 | 70502400 |
Organising pneumonia | 13.45 | 9.84 | 24 | 416767 | 10026 | 70501627 |
Accident | 13.43 | 9.84 | 81 | 416710 | 7210 | 70504443 |
Immunosuppressant drug level increased | 13.41 | 9.84 | 16 | 416775 | 7891 | 70503762 |
Road traffic accident | 13.39 | 9.84 | 282 | 416509 | 34400 | 70477253 |
Heteroplasia | 13.36 | 9.84 | 4 | 416787 | 5 | 70511648 |
Tachyphrenia | 13.35 | 9.84 | 33 | 416758 | 1918 | 70509735 |
Tenosynovitis | 13.35 | 9.84 | 40 | 416751 | 13936 | 70497717 |
Liver function test abnormal | 13.34 | 9.84 | 266 | 416525 | 60880 | 70450773 |
Stillbirth | 13.33 | 9.84 | 3 | 416788 | 3802 | 70507851 |
Face oedema | 13.29 | 9.84 | 92 | 416699 | 25547 | 70486106 |
Hypercholesterolaemia | 13.24 | 9.84 | 58 | 416733 | 18059 | 70493594 |
Human herpesvirus 6 infection | 13.19 | 9.84 | 6 | 416785 | 4853 | 70506800 |
Cytomegalovirus test positive | 13.19 | 9.84 | 8 | 416783 | 5500 | 70506153 |
Altered state of consciousness | 13.18 | 9.84 | 161 | 416630 | 39861 | 70471792 |
Jaundice cholestatic | 13.15 | 9.84 | 21 | 416770 | 9163 | 70502490 |
Brain injury | 13.11 | 9.84 | 107 | 416684 | 10510 | 70501143 |
Hypocalcaemia | 13.10 | 9.84 | 185 | 416606 | 44674 | 70466979 |
Thrombosis | 13.09 | 9.84 | 555 | 416236 | 74850 | 70436803 |
Haemolytic uraemic syndrome | 13.06 | 9.84 | 4 | 416787 | 4126 | 70507527 |
Opisthotonus | 13.05 | 9.84 | 18 | 416773 | 664 | 70510989 |
Hypometabolism | 13.05 | 9.84 | 8 | 416783 | 98 | 70511555 |
Prescription drug used without a prescription | 13.00 | 9.84 | 43 | 416748 | 2954 | 70508699 |
Exostosis | 12.88 | 9.84 | 135 | 416656 | 14210 | 70497443 |
Monoparesis | 12.88 | 9.84 | 45 | 416746 | 3179 | 70508474 |
Gastrointestinal necrosis | 12.87 | 9.84 | 7 | 416784 | 5111 | 70506542 |
Pulmonary alveolar haemorrhage | 12.79 | 9.84 | 26 | 416765 | 10343 | 70501310 |
Myopathy | 12.76 | 9.84 | 61 | 416730 | 18551 | 70493102 |
Accidental overdose | 12.74 | 9.84 | 283 | 416508 | 34838 | 70476815 |
Atrioventricular block complete | 12.69 | 9.84 | 46 | 416745 | 15117 | 70496536 |
Respiratory tract infection | 12.69 | 9.84 | 174 | 416617 | 42224 | 70469429 |
Haematoma | 12.66 | 9.84 | 204 | 416587 | 48214 | 70463439 |
Eyelid myoclonus | 12.64 | 9.84 | 8 | 416783 | 104 | 70511549 |
Abnormal dreams | 12.64 | 9.84 | 106 | 416685 | 10497 | 70501156 |
Product adhesion issue | 12.58 | 9.84 | 38 | 416753 | 2486 | 70509167 |
Prophylaxis | 12.57 | 9.84 | 4 | 416787 | 7 | 70511646 |
Nocturia | 12.48 | 9.84 | 118 | 416673 | 12086 | 70499567 |
Breast cancer stage II | 12.47 | 9.84 | 8 | 416783 | 5338 | 70506315 |
Eyelid oedema | 12.47 | 9.84 | 36 | 416755 | 12691 | 70498962 |
Cardiac failure chronic | 12.45 | 9.84 | 26 | 416765 | 10243 | 70501410 |
CSF neutrophil count increased | 12.43 | 9.84 | 3 | 416788 | 0 | 70511653 |
Turbinectomy | 12.43 | 9.84 | 3 | 416788 | 0 | 70511653 |
Tinel's sign | 12.43 | 9.84 | 3 | 416788 | 0 | 70511653 |
Muscle relaxant drug level above therapeutic | 12.43 | 9.84 | 3 | 416788 | 0 | 70511653 |
Ligamentum flavum hypertrophy | 12.43 | 9.84 | 3 | 416788 | 0 | 70511653 |
Systemic candida | 12.38 | 9.84 | 10 | 416781 | 5924 | 70505729 |
Gingival atrophy | 12.38 | 9.84 | 7 | 416784 | 73 | 70511580 |
Hypoalbuminaemia | 12.34 | 9.84 | 64 | 416727 | 19058 | 70492595 |
Hyperacusis | 12.32 | 9.84 | 33 | 416758 | 2015 | 70509638 |
Arrhythmia | 12.32 | 9.84 | 244 | 416547 | 55899 | 70455754 |
Hypertransaminasaemia | 12.29 | 9.84 | 21 | 416770 | 8922 | 70502731 |
Rapid eye movements sleep abnormal | 12.28 | 9.84 | 11 | 416780 | 248 | 70511405 |
Intercepted medication error | 12.28 | 9.84 | 20 | 416771 | 857 | 70510796 |
Metastases to bone | 12.24 | 9.84 | 79 | 416712 | 22297 | 70489356 |
Pneumonia fungal | 12.24 | 9.84 | 25 | 416766 | 9928 | 70501725 |
JC polyomavirus test positive | 12.23 | 9.84 | 25 | 416766 | 1279 | 70510374 |
Osteomyelitis | 12.19 | 9.84 | 248 | 416543 | 30070 | 70481583 |
Formication | 12.19 | 9.84 | 57 | 416734 | 4600 | 70507053 |
Generalised tonic-clonic seizure | 12.19 | 9.84 | 326 | 416465 | 41335 | 70470318 |
Ventricular tachycardia | 12.19 | 9.84 | 146 | 416645 | 36277 | 70475376 |
Pneumatosis intestinalis | 12.18 | 9.84 | 10 | 416781 | 5877 | 70505776 |
Blood potassium increased | 12.17 | 9.84 | 227 | 416564 | 27099 | 70484554 |
Erythema multiforme | 12.12 | 9.84 | 53 | 416738 | 16511 | 70495142 |
Drug tolerance | 12.12 | 9.84 | 80 | 416711 | 7348 | 70504305 |
Pharyngitis | 12.10 | 9.84 | 70 | 416721 | 20281 | 70491372 |
Hypertensive urgency | 12.08 | 9.84 | 13 | 416778 | 369 | 70511284 |
Ejaculation delayed | 12.07 | 9.84 | 9 | 416782 | 155 | 70511498 |
Increased appetite | 12.07 | 9.84 | 105 | 416686 | 10508 | 70501145 |
Gastrointestinal inflammation | 12.06 | 9.84 | 13 | 416778 | 6710 | 70504943 |
Bronchial secretion retention | 12.01 | 9.84 | 42 | 416749 | 2968 | 70508685 |
Candida infection | 11.99 | 9.84 | 137 | 416654 | 34336 | 70477317 |
Caesarean section | 11.99 | 9.84 | 32 | 416759 | 11575 | 70500078 |
Toxicologic test abnormal | 11.92 | 9.84 | 25 | 416766 | 1302 | 70510351 |
Vulvar basal cell carcinoma | 11.90 | 9.84 | 5 | 416786 | 25 | 70511628 |
Muscle contractions involuntary | 11.88 | 9.84 | 45 | 416746 | 3306 | 70508347 |
Hypernatraemia | 11.85 | 9.84 | 37 | 416754 | 12724 | 70498929 |
Eczema | 11.85 | 9.84 | 134 | 416657 | 33647 | 70478006 |
Application site vesicles | 11.85 | 9.84 | 25 | 416766 | 1308 | 70510345 |
Haemorrhage intracranial | 11.83 | 9.84 | 91 | 416700 | 24686 | 70486967 |
Oesophageal pain | 11.83 | 9.84 | 49 | 416742 | 3753 | 70507900 |
Toe operation | 11.81 | 9.84 | 15 | 416776 | 510 | 70511143 |
Urticaria | 11.78 | 9.84 | 812 | 415979 | 162237 | 70349416 |
Lipodystrophy acquired | 11.77 | 9.84 | 5 | 416786 | 4211 | 70507442 |
Burns second degree | 11.68 | 9.84 | 21 | 416770 | 975 | 70510678 |
Abortion induced | 11.67 | 9.84 | 13 | 416778 | 6612 | 70505041 |
Neuropathic arthropathy | 11.66 | 9.84 | 12 | 416779 | 323 | 70511330 |
Peroneal nerve palsy | 11.65 | 9.84 | 64 | 416727 | 5506 | 70506147 |
Hepatic encephalopathy | 11.64 | 9.84 | 79 | 416712 | 22039 | 70489614 |
Naevus haemorrhage | 11.61 | 9.84 | 8 | 416783 | 121 | 70511532 |
Bladder disorder | 11.60 | 9.84 | 86 | 416705 | 8203 | 70503450 |
Antipsychotic drug level increased | 11.56 | 9.84 | 9 | 416782 | 5431 | 70506222 |
Substance abuse | 11.54 | 9.84 | 98 | 416693 | 9739 | 70501914 |
Retinal detachment | 11.53 | 9.84 | 20 | 416771 | 8447 | 70503206 |
Bone contusion | 11.53 | 9.84 | 23 | 416768 | 1156 | 70510497 |
Infective pulmonary exacerbation of cystic fibrosis | 11.47 | 9.84 | 35 | 416756 | 12123 | 70499530 |
Oral herpes | 11.47 | 9.84 | 89 | 416702 | 24097 | 70487556 |
Spinal disorder | 11.43 | 9.84 | 93 | 416698 | 9127 | 70502526 |
Ligament sprain | 11.42 | 9.84 | 114 | 416677 | 11849 | 70499804 |
Implant site inflammation | 11.40 | 9.84 | 10 | 416781 | 219 | 70511434 |
Visual field tests abnormal | 11.35 | 9.84 | 4 | 416787 | 11 | 70511642 |
Concomitant disease aggravated | 11.34 | 9.84 | 35 | 416756 | 12079 | 70499574 |
Breast disorder | 11.32 | 9.84 | 31 | 416760 | 1918 | 70509735 |
Basal cell carcinoma | 11.31 | 9.84 | 135 | 416656 | 33563 | 70478090 |
Blood potassium decreased | 11.30 | 9.84 | 328 | 416463 | 42093 | 70469560 |
Hypoacusis | 11.28 | 9.84 | 224 | 416567 | 27045 | 70484608 |
Liver function test increased | 11.20 | 9.84 | 136 | 416655 | 33711 | 70477942 |
Cytopenia | 11.17 | 9.84 | 58 | 416733 | 17265 | 70494388 |
Screaming | 11.17 | 9.84 | 47 | 416744 | 3625 | 70508028 |
Stress cardiomyopathy | 11.11 | 9.84 | 26 | 416765 | 9836 | 70501817 |
Chest X-ray abnormal | 11.09 | 9.84 | 76 | 416715 | 7068 | 70504585 |
Disturbance in social behaviour | 11.08 | 9.84 | 5 | 416786 | 4062 | 70507591 |
Narcolepsy | 11.05 | 9.84 | 23 | 416768 | 1192 | 70510461 |
Retinal deposits | 11.02 | 9.84 | 8 | 416783 | 132 | 70511521 |
Rash erythematous | 10.98 | 9.84 | 226 | 416565 | 51492 | 70460161 |
Radiation pneumonitis | 10.94 | 9.84 | 4 | 416787 | 3689 | 70507964 |
Myotonia | 10.93 | 9.84 | 10 | 416781 | 232 | 70511421 |
Carotid artery disease | 10.92 | 9.84 | 33 | 416758 | 2160 | 70509493 |
Joint destruction | 10.91 | 9.84 | 7 | 416784 | 4671 | 70506982 |
Hypotension | 10.89 | 9.84 | 2153 | 414638 | 402228 | 70109425 |
Disinhibition | 10.87 | 9.84 | 34 | 416757 | 2267 | 70509386 |
Blood urea increased | 10.85 | 9.84 | 197 | 416594 | 45712 | 70465941 |
Vertebral foraminal stenosis | 10.84 | 9.84 | 21 | 416770 | 1033 | 70510620 |
Leg amputation | 10.83 | 9.84 | 45 | 416746 | 3451 | 70508202 |
Acute generalised exanthematous pustulosis | 10.83 | 9.84 | 50 | 416741 | 15347 | 70496306 |
Vascular malformation | 10.81 | 9.84 | 12 | 416779 | 353 | 70511300 |
Suicidal behaviour | 10.81 | 9.84 | 41 | 416750 | 3015 | 70508638 |
Pustular psoriasis | 10.79 | 9.84 | 7 | 416784 | 4643 | 70507010 |
Ulcer | 10.76 | 9.84 | 98 | 416693 | 25656 | 70485997 |
Anal incontinence | 10.75 | 9.84 | 146 | 416645 | 16344 | 70495309 |
Lymphadenopathy | 10.72 | 9.84 | 212 | 416579 | 48579 | 70463074 |
Retinal haemorrhage | 10.69 | 9.84 | 18 | 416773 | 7692 | 70503961 |
Medical induction of coma | 10.68 | 9.84 | 7 | 416784 | 97 | 70511556 |
Glycosylated haemoglobin decreased | 10.66 | 9.84 | 16 | 416775 | 638 | 70511015 |
Granuloma | 10.64 | 9.84 | 18 | 416773 | 7677 | 70503976 |
Application site burn | 10.61 | 9.84 | 18 | 416773 | 798 | 70510855 |
Child abuse | 10.59 | 9.84 | 12 | 416779 | 361 | 70511292 |
Infected skin ulcer | 10.58 | 9.84 | 41 | 416750 | 3045 | 70508608 |
Oesophageal obstruction | 10.56 | 9.84 | 19 | 416772 | 883 | 70510770 |
Left ventricular dysfunction | 10.55 | 9.84 | 62 | 416729 | 17895 | 70493758 |
Right ventricular failure | 10.55 | 9.84 | 82 | 416709 | 22192 | 70489461 |
Gastric bypass | 10.54 | 9.84 | 22 | 416769 | 1142 | 70510511 |
Pulmonary renal syndrome | 10.52 | 9.84 | 15 | 416776 | 571 | 70511082 |
Upper respiratory tract inflammation | 10.50 | 9.84 | 5 | 416786 | 3937 | 70507716 |
Gastroenteritis | 10.49 | 9.84 | 125 | 416666 | 31088 | 70480565 |
Open angle glaucoma | 10.44 | 9.84 | 13 | 416778 | 433 | 70511220 |
Myoclonic dystonia | 10.43 | 9.84 | 4 | 416787 | 15 | 70511638 |
Free androgen index decreased | 10.43 | 9.84 | 4 | 416787 | 15 | 70511638 |
Lymphoma | 10.41 | 9.84 | 51 | 416740 | 15411 | 70496242 |
Knee deformity | 10.40 | 9.84 | 20 | 416771 | 978 | 70510675 |
Intentional underdose | 10.38 | 9.84 | 32 | 416759 | 2117 | 70509536 |
Nervous system cyst | 10.37 | 9.84 | 3 | 416788 | 3 | 70511650 |
Subdural haematoma | 10.36 | 9.84 | 116 | 416675 | 29182 | 70482471 |
Multiple-drug resistance | 10.36 | 9.84 | 17 | 416774 | 7338 | 70504315 |
Nystagmus | 10.35 | 9.84 | 92 | 416699 | 9263 | 70502390 |
Disability | 10.33 | 9.84 | 49 | 416742 | 14934 | 70496719 |
International normalised ratio increased | 10.31 | 9.84 | 379 | 416412 | 80347 | 70431306 |
B-cell lymphoma | 10.30 | 9.84 | 13 | 416778 | 6256 | 70505397 |
Intra-abdominal haemorrhage | 10.28 | 9.84 | 6 | 416785 | 4212 | 70507441 |
Feeling of body temperature change | 10.27 | 9.84 | 57 | 416734 | 4922 | 70506731 |
Decreased appetite | 10.27 | 9.84 | 1603 | 415188 | 303177 | 70208476 |
CD8 lymphocytes decreased | 10.25 | 9.84 | 10 | 416781 | 252 | 70511401 |
Pineal gland cyst | 10.23 | 9.84 | 4 | 416787 | 16 | 70511637 |
Neck surgery | 10.16 | 9.84 | 27 | 416764 | 1641 | 70510012 |
Dissociation | 10.10 | 9.84 | 43 | 416748 | 3333 | 70508320 |
Subarachnoid haemorrhage | 10.10 | 9.84 | 70 | 416721 | 19434 | 70492219 |
Skin plaque | 10.08 | 9.84 | 27 | 416764 | 9756 | 70501897 |
Vasoplegia syndrome | 10.08 | 9.84 | 3 | 416788 | 3153 | 70508500 |
Lung adenocarcinoma stage I | 10.07 | 9.84 | 5 | 416786 | 39 | 70511614 |
Femoral artery dissection | 10.07 | 9.84 | 5 | 416786 | 39 | 70511614 |
Injection site reaction | 10.07 | 9.84 | 373 | 416418 | 49479 | 70462174 |
Second primary malignancy | 10.02 | 9.84 | 41 | 416750 | 13010 | 70498643 |
Food allergy | 9.99 | 9.84 | 22 | 416769 | 8502 | 70503151 |
Cortisol abnormal | 9.96 | 9.84 | 6 | 416785 | 71 | 70511582 |
Libido decreased | 9.96 | 9.84 | 56 | 416735 | 4860 | 70506793 |
Artery dissection | 9.93 | 9.84 | 9 | 416782 | 206 | 70511447 |
Metastases to peritoneum | 9.93 | 9.84 | 5 | 416786 | 3814 | 70507839 |
Abnormal weight gain | 9.92 | 9.84 | 33 | 416758 | 2273 | 70509380 |
Drug screen false positive | 9.92 | 9.84 | 20 | 416771 | 1013 | 70510640 |
Arachnoiditis | 9.92 | 9.84 | 16 | 416775 | 680 | 70510973 |
Benign neoplasm of spinal cord | 9.91 | 9.84 | 3 | 416788 | 4 | 70511649 |
Camptodactyly congenital | 9.91 | 9.84 | 3 | 416788 | 4 | 70511649 |
Diffuse large B-cell lymphoma recurrent | 9.90 | 9.84 | 4 | 416787 | 3472 | 70508181 |
Neutrophilia | 9.88 | 9.84 | 17 | 416774 | 7204 | 70504449 |
Heat exhaustion | 9.87 | 9.84 | 10 | 416781 | 264 | 70511389 |
Malabsorption from injection site | 9.86 | 9.84 | 4 | 416787 | 18 | 70511635 |
Dermatitis bullous | 9.84 | 9.84 | 40 | 416751 | 12717 | 70498936 |
Bronchospasm | 9.84 | 9.84 | 86 | 416705 | 22706 | 70488947 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Trismus | 42.20 | 24.61 | 17 | 323 | 129 | 89323 |
Source | Code | Description |
---|---|---|
ATC | N03AX12 | NERVOUS SYSTEM ANTIEPILEPTICS ANTIEPILEPTICS Other antiepileptics |
FDA PE | N0000008486 | Decreased Central Nervous System Disorganized Electrical Activity |
MeSH PA | D000700 | Analgesics |
MeSH PA | D014151 | Anti-Anxiety Agents |
MeSH PA | D000927 | Anticonvulsants |
MeSH PA | D018692 | Antimanic Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D018691 | Excitatory Amino Acid Antagonists |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D011619 | Psychotropic Drugs |
MeSH PA | D018689 | Sensory System Agents |
MeSH PA | D014149 | Tranquilizing Agents |
FDA EPC | N0000175753 | Anti-epileptic Agent |
CHEBI has role | CHEBI:35623 | anticonvulsants |
CHEBI has role | CHEBI:35703 | Xenobiotic |
CHEBI has role | CHEBI:38215 | calcium channel blockers |
CHEBI has role | CHEBI:78298 | environmental contaminants |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Postherpetic neuralgia | indication | 2177002 | |
Restless legs | indication | 32914008 | DOID:0050425 |
Partial Epilepsy Treatment Adjunct | indication | ||
Alcohol use disorder | off-label use | 7200002 | |
Menopausal night sweats | off-label use | 42984000 | |
Chronic cough | off-label use | 68154008 | |
Chronic pain | off-label use | 82423001 | |
Insomnia | off-label use | 193462001 | |
Anxiety disorder | off-label use | 197480006 | DOID:2030 |
Menopausal flushing | off-label use | 198436008 | |
Fibromyalgia | off-label use | 203082005 | DOID:631 |
Neuropathic pain | off-label use | 247398009 | |
Chronic pruritus | off-label use | 418363000 | |
Refractory pruritis | off-label use | 418363000 | |
Post-stroke nausea | off-label use | 422587007 | |
Essential tremor | off-label use | 609558009 | DOID:4990 |
Intractable hiccups | off-label use | 716771000 | |
Acute postoperative pain | off-label use | 107401000119105 | |
Suicidal thoughts | contraindication | 6471006 | |
Depressive disorder | contraindication | 35489007 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.02 | acidic |
pKa2 | 10.31 | Basic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
300MG | GRALISE | ALMATICA | N022544 | Jan. 28, 2011 | RX | TABLET | ORAL | 8192756 | Oct. 25, 2022 | TREATMENT WITH GABAPENTIN, INCLUDING TREATMENT OF NEUROPATHIC PAIN, INCLUDING NEUROPATHIC PAIN ASSOCIATED WITH POSTHERPETIC NEURALGIA |
300MG | GRALISE | ALMATICA | N022544 | Jan. 28, 2011 | RX | TABLET | ORAL | 8252332 | Oct. 25, 2022 | TREATMENT WITH GABAPENTIN, INCLUDING TREATMENT OF NEUROPATHIC PAIN, INCLUDING NEUROPATHIC PAIN ASSOCIATED WITH POSTHERPETIC NEURALGIA |
300MG | GRALISE | ALMATICA | N022544 | Jan. 28, 2011 | RX | TABLET | ORAL | 8333992 | Oct. 25, 2022 | TREATMENT WITH GABAPENTIN, INCLUDING TREATMENT OF NEUROPATHIC PAIN, INCLUDING NEUROPATHIC PAIN ASSOCIATED WITH POSTHERPETIC NEURALGIA |
600MG | GRALISE | ALMATICA | N022544 | Jan. 28, 2011 | RX | TABLET | ORAL | 8192756 | Oct. 25, 2022 | TREATMENT WITH GABAPENTIN, INCLUDING TREATMENT OF NEUROPATHIC PAIN, INCLUDING NEUROPATHIC PAIN ASSOCIATED WITH POSTHERPETIC NEURALGIA |
600MG | GRALISE | ALMATICA | N022544 | Jan. 28, 2011 | RX | TABLET | ORAL | 8252332 | Oct. 25, 2022 | TREATMENT WITH GABAPENTIN, INCLUDING TREATMENT OF NEUROPATHIC PAIN, INCLUDING NEUROPATHIC PAIN ASSOCIATED WITH POSTHERPETIC NEURALGIA |
600MG | GRALISE | ALMATICA | N022544 | Jan. 28, 2011 | RX | TABLET | ORAL | 8333992 | Oct. 25, 2022 | TREATMENT WITH GABAPENTIN, INCLUDING TREATMENT OF NEUROPATHIC PAIN, INCLUDING NEUROPATHIC PAIN ASSOCIATED WITH POSTHERPETIC NEURALGIA |
300MG | GRALISE | ALMATICA | N022544 | Jan. 28, 2011 | RX | TABLET | ORAL | 7438927 | Feb. 26, 2024 | TREATMENT WITH GABAPENTIN, INCLUDING TREATMENT OF NEUROPATHIC PAIN, INCLUDING NEUROPATHIC PAIN ASSOCIATED WITH POSTHERPETIC NEURALGIA |
600MG | GRALISE | ALMATICA | N022544 | Jan. 28, 2011 | RX | TABLET | ORAL | 7438927 | Feb. 26, 2024 | TREATMENT WITH GABAPENTIN, INCLUDING TREATMENT OF NEUROPATHIC PAIN, INCLUDING NEUROPATHIC PAIN ASSOCIATED WITH POSTHERPETIC NEURALGIA |
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Voltage-dependent calcium channel subunit alpha-2/delta-2 | Ion channel | MODULATOR | IC50 | 6.93 | SCIENTIFIC LITERATURE | SCIENTIFIC LITERATURE | |||
Voltage-dependent calcium channel subunit alpha-2/delta-1 | Ion channel | MODULATOR | IC50 | 7.26 | WOMBAT-PK | CHEMBL | |||
Adenosine receptor A1 | GPCR | WOMBAT-PK | |||||||
Gamma-aminobutyric acid type B receptor subunit 2 | GPCR | WOMBAT-PK | |||||||
Glutamate receptor ionotropic, NMDA 3A | Ion channel | WOMBAT-PK | |||||||
Large neutral amino acids transporter small subunit 1 | Transporter | IC50 | 4.52 | WOMBAT-PK | |||||
Sodium channel protein type 5 subunit alpha | Ion channel | WOMBAT-PK | |||||||
Potassium voltage-gated channel subfamily KQT member 3 | Ion channel | ACTIVATOR | EC50 | 8.28 | IUPHAR | ||||
Potassium voltage-gated channel subfamily KQT member 5 | Ion channel | ACTIVATOR | EC50 | 8.72 | IUPHAR | ||||
Alpha-2A adrenergic receptor | GPCR | WOMBAT-PK | |||||||
Voltage-dependent calcium channel subunit alpha-2/delta-1 | Ion channel | Ki | 6.92 | CHEMBL | |||||
Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit | Ion channel | IC50 | 7.15 | CHEMBL |
ID | Source |
---|---|
4020833 | VUID |
N0000148345 | NUI |
D00332 | KEGG_DRUG |
4020833 | VANDF |
C0060926 | UMLSCUI |
CHEBI:42797 | CHEBI |
GBN | PDB_CHEM_ID |
CHEMBL940 | ChEMBL_ID |
DB00996 | DRUGBANK_ID |
D000077206 | MESH_DESCRIPTOR_UI |
3446 | PUBCHEM_CID |
5094 | INN_ID |
C081867 | MESH_SUPPLEMENTAL_RECORD_UI |
5483 | IUPHAR_LIGAND_ID |
6CW7F3G59X | UNII |
196498 | RXNORM |
2269 | MMSL |
4770 | MMSL |
60712 | MMSL |
d03182 | MMSL |
004415 | NDDF |
108402001 | SNOMEDCT_US |
386845007 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0401 | TABLET, FILM COATED | 800 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0401 | TABLET, FILM COATED | 800 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0513 | TABLET, FILM COATED | 600 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0513 | TABLET, FILM COATED | 600 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0803 | CAPSULE | 100 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0803 | CAPSULE | 100 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0805 | CAPSULE | 300 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0805 | CAPSULE | 300 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0806 | CAPSULE | 400 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0806 | CAPSULE | 400 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-2012 | SOLUTION | 250 mg | ORAL | NDA | 31 sections |
Neurontin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-2012 | SOLUTION | 250 mg | ORAL | NDA | 31 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0228-2636 | TABLET, FILM COATED | 600 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0228-2636 | TABLET, FILM COATED | 600 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0228-2637 | TABLET, FILM COATED | 800 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0228-2637 | TABLET, FILM COATED | 800 mg | ORAL | ANDA | 26 sections |
GABAPENTIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0440-5562 | TABLET, FILM COATED | 600 mg | ORAL | ANDA | 24 sections |
GABAPENTIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0440-5563 | TABLET, FILM COATED | 800 mg | ORAL | ANDA | 24 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0440-7559 | CAPSULE | 300 mg | ORAL | ANDA | 14 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8132 | TABLET | 800 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8132 | TABLET | 800 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8230 | CAPSULE | 100 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8231 | CAPSULE | 300 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8232 | CAPSULE | 400 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8233 | TABLET | 600 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8233 | TABLET | 600 mg | ORAL | ANDA | 29 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8340 | CAPSULE | 100 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8340 | CAPSULE | 100 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8341 | CAPSULE | 300 mg | ORAL | ANDA | 26 sections |
Gabapentin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8341 | CAPSULE | 300 mg | ORAL | ANDA | 26 sections |