fructose 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1252 6347-01-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • D-Fructopyranose
  • fructose
  • D-(-)-Fructose
  • D-(-)-Levulose
  • D-arabino-2-Hexulose
  • fruit sugar
  • levulose
  • nevulose
A monosaccharide in sweet fruits and honey that is soluble in water, alcohol, or ether. It is used as a preservative and an intravenous infusion in parenteral feeding.
  • Molecular weight: 180.16
  • Formula: C6H12O6
  • CLOGP: -2.18
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 5
  • TPSA: 110.38
  • ALOGS: 0.82
  • ROTB: 1

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 50 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Vaginal flatulence 102.06 92.72 18 699 2557 79741114

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V06DC02 VARIOUS
GENERAL NUTRIENTS
OTHER NUTRIENTS
Carbohydrates
MeSH PA D005421 Flavoring Agents
MeSH PA D005503 Food Additives
MeSH PA D013549 Sweetening Agents
CHEBI has role CHEBI:75772 S. cerevisiae metabolites
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:78675 fundamental metabolites
CHEBI has role CHEBI:50505 sweeteners

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.38 acidic
pKa2 13.19 acidic
pKa3 13.63 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Glycine receptor subunit alpha-1 Ion channel EC50 4.90 CHEMBL

External reference:

IDSource
4018693 VUID
N0000147002 NUI
D00114 KEGG_DRUG
4018693 VANDF
C0016745 UMLSCUI
CHEBI:28757 CHEBI
BDF PDB_CHEM_ID
CHEMBL604608 ChEMBL_ID
DB04173 DRUGBANK_ID
D005632 MESH_DESCRIPTOR_UI
2723872 PUBCHEM_CID
6YSS42VSEV UNII
4570 RXNORM
NOCODE MMSL
000918 NDDF
002606 NDDF
39860005 SNOMEDCT_US
58202007 SNOMEDCT_US
57-48-7 SECONDARY_CAS_RN

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
good sense nausea relief HUMAN OTC DRUG LABEL 3 0113-0112 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Nausea Relief HUMAN OTC DRUG LABEL 3 0363-0056 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Nausea Relief HUMAN OTC DRUG LABEL 3 0363-0056 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Anti Nausea HUMAN OTC DRUG LABEL 3 0536-1302 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
Anti Nausea HUMAN OTC DRUG LABEL 3 0536-1302 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
formula em HUMAN OTC DRUG LABEL 3 0904-0049 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
nausea relief HUMAN OTC DRUG LABEL 3 11822-0401 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
signature care anti nausea HUMAN OTC DRUG LABEL 3 21130-694 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Kroger Anti NauseaCherry Flavor HUMAN OTC DRUG LABEL 3 30142-708 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
Kroger Anti NauseaCherry Flavor HUMAN OTC DRUG LABEL 3 30142-708 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
Kroger Anti NauseaCherry Flavor HUMAN OTC DRUG LABEL 3 30142-708 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
nausea relief HUMAN OTC DRUG LABEL 3 30142-709 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Anti Nausea Liquid HUMAN OTC DRUG LABEL 3 36800-708 SOLUTION 1.87 g ORAL Unapproved drug other 13 sections
Anti Nausea Liquid HUMAN OTC DRUG LABEL 3 36800-708 SOLUTION 1.87 g ORAL Unapproved drug other 13 sections
nausea relief HUMAN OTC DRUG LABEL 3 37808-501 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
HEB Anti Nausea HUMAN OTC DRUG LABEL 3 37808-883 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
HEB Anti Nausea HUMAN OTC DRUG LABEL 3 37808-883 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
equaline anti nausea HUMAN OTC DRUG LABEL 3 41163-630 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Meijer Anti Nausea HUMAN OTC DRUG LABEL 3 41250-495 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
Meijer Anti Nausea HUMAN OTC DRUG LABEL 3 41250-495 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
Nausea Relief HUMAN OTC DRUG LABEL 3 41250-502 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Good Neighbor Pharmacy Nausea Relief HUMAN OTC DRUG LABEL 3 46122-296 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Good Neighbor Anti NauseaCherry Flavor HUMAN OTC DRUG LABEL 3 46122-729 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
Good Neighbor Anti NauseaCherry Flavor HUMAN OTC DRUG LABEL 3 46122-729 LIQUID 1.87 g ORAL Unapproved drug other 13 sections
sunmark anti nausea HUMAN OTC DRUG LABEL 3 49348-576 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
sunmark anti nausea HUMAN OTC DRUG LABEL 3 49348-576 SOLUTION 1.87 g ORAL Unapproved drug other 14 sections
Nauzene HUMAN OTC DRUG LABEL 3 52389-172 SYRUP 4.17 g ORAL OTC monograph not final 28 sections
Discount Drug Mart nausea controlCherry Flavor HUMAN OTC DRUG LABEL 3 53943-708 SOLUTION 1.87 g ORAL Unapproved drug other 13 sections
Discount Drug Mart nausea controlCherry Flavor HUMAN OTC DRUG LABEL 3 53943-708 SOLUTION 1.87 g ORAL Unapproved drug other 13 sections
Discount Drug Mart nausea controlCherry Flavor HUMAN OTC DRUG LABEL 3 53943-708 SOLUTION 1.87 g ORAL Unapproved drug other 13 sections