Molfile
Inchi
Smiles
Synonyms:
-
alizapride
-
alizapride hydrochloride
-
alizapride HCl
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a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Its effect is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone (CTZ) in the central nervous system (CNS), this action prevents nausea and vomiting triggered by most stimuli.
- Molecular weight: 315.38
- Formula: C16H21N5O2
- CLOGP: 2.53
- LIPINSKI: 0
- HAC: 7
- HDO: 2
- TPSA: 83.14
- ALOGS: -2.84
- ROTB: 6
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