flubendazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anthelminthics, tiabendazole derivatives 1186 31430-15-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • flubendazole
  • flumoxane
  • fluvermal
  • flubendazol
the p-fluoro analog of mebendazole
  • Molecular weight: 313.29
  • Formula: C16H12FN3O3
  • CLOGP: 3.25
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 84.08
  • ALOGS: -4.04
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.20 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P02CA05 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTHELMINTICS
ANTINEMATODAL AGENTS
Benzimidazole derivatives
MeSH PA D000871 Anthelmintics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000969 Antinematodal Agents
MeSH PA D000977 Antiparasitic Agents
CHEBI has role CHEBI:35444 antinematodal drugs
CHEBI has role CHEBI:50905 teratogeno

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.61 acidic
pKa2 13.2 acidic
pKa3 2.93 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04200 KEGG_DRUG
C0060477 UMLSCUI
CHEBI:77095 CHEBI
CHEMBL1454946 ChEMBL_ID
DB08974 DRUGBANK_ID
C018945 MESH_SUPPLEMENTAL_RECORD_UI
35802 PUBCHEM_CID
3904 INN_ID
R8M46911LR UNII
25096 RXNORM
005808 NDDF
703367001 SNOMEDCT_US
703901007 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
ZELCOM HUMAN OTC DRUG LABEL 1 72689-0009 TABLET 500 mg ORAL unapproved drug other 7 sections