DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
faropenem 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
analogues of penicillanic acid antibiotics modified in the five-membered ring
1131
106560-14-9
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
faropenem sodium hydrate
fropenem
faropenem sodium
faropenem
Molecular weight: 285.31
Formula: C12H15NO5S
CLOGP: 0.16
LIPINSKI: 0
HAC: 6
HDO: 2
TPSA: 87.07
ALOGS: -1.29
ROTB: 3
Drug dosage:
Dose
Unit
Route
0.75
g
O
ADMET properties:
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Property
Value
Reference
CL (Clearance)
2.23 mL/min/kg
Lombardo F, Berellini G, Obach RS
t_half (Half-life)
1.40 hours
Lombardo F, Berellini G, Obach RS
Vd (Volume of distribution)
0.18 L/kg
Lombardo F, Berellini G, Obach RS
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
J01DI03
ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
OTHER BETA-LACTAM ANTIBACTERIALS
Other cephalosporins and penems
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Bacterial infection of skin
indication
128936008
Respiratory tract infection
indication
275498002
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
3.21
acidic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
FPM
PDB_CHEM_ID
10808
IUPHAR_LIGAND_ID
1162766006
SNOMEDCT_US
1162884001
SNOMEDCT_US
1162886004
SNOMEDCT_US
122547-49-3
SECONDARY_CAS_RN
65894
PUBCHEM_CID
7086
INN_ID
C0541153
UMLSCUI
C107057
MESH_SUPPLEMENTAL_RECORD_UI
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Pharmaceutical products:
None
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faropenem