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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
FAQ
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
ethyl loflazepate 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
diazepam derivatives
1092
29177-84-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
ethyl flucozepate
CM 6912
ethyl loflazepate
meilax
victan
CM6912
CM-6912
Molecular weight: 360.77
Formula: C18H14ClFN2O3
CLOGP: 3.19
LIPINSKI: 0
HAC: 5
HDO: 1
TPSA: 67.76
ALOGS: -4.84
ROTB: 4
Drug dosage:
Dose
Unit
Route
2
mg
O
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
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MedDRA adverse event term
Likelihood ratio
Likelihood ratio threshold
Patients taking drug having adverse event
Patients taking drug not having adverse event
Patients not taking drug having adverse event
Patients not taking drug not having adverse event
Altered state of consciousness
52.10
29.39
18
932
25212
63462860
Tongue oedema
50.11
29.39
12
938
4574
63483498
Rash maculo-papular
33.88
29.39
14
936
31882
63456190
Neuroleptic malignant syndrome
30.38
29.39
10
940
12046
63476026
Showing 1 to 4 of 4 entries
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1
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FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
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MedDRA adverse event term
Likelihood ratio
Likelihood ratio threshold
Patients taking drug having adverse event
Patients taking drug not having adverse event
Patients not taking drug having adverse event
Patients not taking drug not having adverse event
Altered state of consciousness
57.18
26.31
24
1524
43798
79699042
Tongue oedema
41.76
26.31
12
1536
7105
79735735
Parkinsonism
39.20
26.31
14
1534
16570
79726270
Irritability
35.87
26.31
17
1531
41127
79701713
Neuroleptic malignant syndrome
35.61
26.31
15
1533
27544
79715296
Suicide attempt
34.67
26.31
21
1527
82911
79659929
Mallory-Weiss syndrome
31.86
26.31
8
1540
2844
79739996
Intentional overdose
29.96
26.31
21
1527
105939
79636901
Patient isolation
28.13
26.31
4
1544
63
79742777
Pressure of speech
27.21
26.31
6
1542
1222
79741618
Showing 1 to 10 of 11 entries
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FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
N05BA18
NERVOUS SYSTEM
PSYCHOLEPTICS
ANXIOLYTICS
Benzodiazepine derivatives
MeSH PA
D014151
Anti-Anxiety Agents
MeSH PA
D002491
Central Nervous System Agents
MeSH PA
D002492
Central Nervous System Depressants
MeSH PA
D011619
Psychotropic Drugs
MeSH PA
D014149
Tranquilizing Agents
Showing 1 to 6 of 6 entries
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Depressive disorder
indication
35489007
Anxiety
indication
48694002
Myasthenia gravis
contraindication
91637004
DOID:437
Angle-closure glaucoma
contraindication
392291006
DOID:13550
Showing 1 to 4 of 4 entries
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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entries
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
9.28
acidic
pKa2
9.89
acidic
pKa3
3.83
Basic
Showing 1 to 3 of 3 entries
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1
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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entries
Search:
ID
Source
005857
NDDF
155667
PUBCHEM_CID
24524
RXNORM
3299
PUBCHEM_CID
4837
INN_ID
71735-10-9
SECONDARY_CAS_RN
769093001
SNOMEDCT_US
C0059772
UMLSCUI
C0099755
UMLSCUI
C029617
MESH_SUPPLEMENTAL_RECORD_UI
Showing 1 to 10 of 17 entries
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Pharmaceutical products:
None
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ethyl loflazepate