etamsylate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
1075 2624-44-4

Description:

MoleculeDescription

Synonyms:

  • ethamsylate
  • cyclonamine
  • dicinone
  • diethylammonium 2,5-dihydroxybenzenesulfonate
  • etamsylate
Benzenesulfonate derivative used as a systemic hemostatic.
  • Molecular weight: 263.31
  • Formula: C10H17NO5S
  • CLOGP: -0.41
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 97.66
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Negative symptoms in schizophrenia 61.98 43.76 8 875 123 90627441
Oligohydramnios 44.74 43.76 11 872 7190 90620374

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Platelet count decreased 60.43 38.80 36 1258 230407 110357598
Anaemia 57.84 38.80 49 1245 547037 110040968
Negative symptoms in schizophrenia 56.36 38.80 8 1286 212 110587793
Leukopenia 43.56 38.80 25 1269 148766 110439239
Neutrophil count decreased 42.73 38.80 23 1271 120918 110467087
Myelosuppression 39.18 38.80 20 1274 94320 110493685

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC B02BX01 BLOOD AND BLOOD FORMING ORGANS
ANTIHEMORRHAGICS
VITAMIN K AND OTHER HEMOSTATICS
Other systemic hemostatics
MeSH PA D003029 Coagulants
MeSH PA D006401 Hematologic Agents
MeSH PA D006490 Hemostatics

Related Drugs by ATC class:

B02BX Other systemic hemostatics 10 drugs
avatrombopagcarbazochromeconcizumabeltrombopagemicizumabfitusiranfostamatiniblusutrombopagmarstacimab-hncqromiplostim

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000166480 NUI
D01282 KEGG_DRUG
CHEBI:31563 CHEBI
CHEMBL1514715 ChEMBL_ID
DB13483 DRUGBANK_ID
4112 RXNORM
003965 NDDF
319848004 SNOMEDCT_US
396048008 SNOMEDCT_US
C0014968 UMLSCUI
D004979 MESH_DESCRIPTOR_UI
1903 INN_ID
17506 PUBCHEM_CID
24YL531VOH UNII

Pharmaceutical products:

None