Stem definition | Drug id | CAS RN |
---|---|---|
antibiotics, produced by Streptomyces strains | 1051 | 1264-62-6 |
None
None
Date | Agency | Company | Orphan |
---|---|---|---|
April 2, 1965 | FDA | ARBOR PHARMS LLC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 4580.36 | 12.44 | 2249 | 22029 | 308438 | 63156306 |
International normalised ratio fluctuation | 227.91 | 12.44 | 69 | 24209 | 2409 | 63462335 |
Bloody discharge | 176.81 | 12.44 | 51 | 24227 | 1500 | 63463244 |
Lyme disease | 133.13 | 12.44 | 50 | 24228 | 3399 | 63461345 |
Abortion spontaneous | 112.52 | 12.44 | 113 | 24165 | 47082 | 63417662 |
Seronegative arthritis | 109.19 | 12.44 | 45 | 24233 | 3914 | 63460830 |
Exposure during pregnancy | 68.26 | 12.44 | 170 | 24108 | 155377 | 63309367 |
Dislocation of vertebra | 58.16 | 12.44 | 38 | 24240 | 8597 | 63456147 |
Anaphylactic reaction | 57.49 | 12.44 | 96 | 24182 | 66004 | 63398740 |
Maternal exposure during pregnancy | 53.28 | 12.44 | 195 | 24083 | 219867 | 63244877 |
Vomiting | 52.77 | 12.44 | 380 | 23898 | 559237 | 62905507 |
Faecal volume decreased | 50.20 | 12.44 | 12 | 24266 | 165 | 63464579 |
Drug interaction | 47.26 | 12.44 | 193 | 24085 | 228938 | 63235806 |
Amniotic cavity infection | 44.03 | 12.44 | 17 | 24261 | 1246 | 63463498 |
Wheezing | 42.44 | 12.44 | 105 | 24173 | 95490 | 63369254 |
Spondylitis | 41.71 | 12.44 | 24 | 24254 | 4330 | 63460414 |
Pneumococcal infection | 38.98 | 12.44 | 12 | 24266 | 443 | 63464301 |
Completed suicide | 38.71 | 12.44 | 5 | 24273 | 145668 | 63319076 |
Death | 37.67 | 12.44 | 53 | 24225 | 374328 | 63090416 |
Mass excision | 37.45 | 12.44 | 11 | 24267 | 345 | 63464399 |
Umbilical erythema | 36.56 | 12.44 | 8 | 24270 | 72 | 63464672 |
Rash | 35.28 | 12.44 | 348 | 23930 | 560523 | 62904221 |
Drug intolerance | 33.99 | 12.44 | 218 | 24060 | 308443 | 63156301 |
Spinal fusion surgery | 33.65 | 12.44 | 23 | 24255 | 5605 | 63459139 |
Vertigo positional | 33.58 | 12.44 | 18 | 24260 | 2831 | 63461913 |
Wound infection | 33.26 | 12.44 | 41 | 24237 | 21369 | 63443375 |
Purpura senile | 32.49 | 12.44 | 11 | 24267 | 552 | 63464192 |
Pain | 31.59 | 12.44 | 161 | 24117 | 740467 | 62724277 |
Necrosis ischaemic | 31.50 | 12.44 | 12 | 24266 | 848 | 63463896 |
Adjustment disorder with depressed mood | 31.09 | 12.44 | 28 | 24250 | 10176 | 63454568 |
Caesarean section | 30.38 | 12.44 | 35 | 24243 | 16997 | 63447747 |
Premature baby | 29.50 | 12.44 | 38 | 24240 | 20697 | 63444047 |
Infection | 29.10 | 12.44 | 168 | 24110 | 229005 | 63235739 |
Tarsal tunnel syndrome | 28.41 | 12.44 | 10 | 24268 | 564 | 63464180 |
Urticaria | 27.56 | 12.44 | 131 | 24147 | 165671 | 63299073 |
Ototoxicity | 26.17 | 12.44 | 12 | 24266 | 1350 | 63463394 |
Serum sickness-like reaction | 25.68 | 12.44 | 9 | 24269 | 501 | 63464243 |
Bronchial obstruction | 25.01 | 12.44 | 12 | 24266 | 1495 | 63463249 |
Drug tolerance decreased | 24.82 | 12.44 | 32 | 24246 | 17441 | 63447303 |
Benign laryngeal neoplasm | 24.63 | 12.44 | 5 | 24273 | 30 | 63464714 |
Beta haemolytic streptococcal infection | 24.45 | 12.44 | 13 | 24265 | 2012 | 63462732 |
Ulcerative keratitis | 23.49 | 12.44 | 14 | 24264 | 2696 | 63462048 |
Breast cancer stage III | 23.15 | 12.44 | 24 | 24254 | 10362 | 63454382 |
Therapeutic product effect incomplete | 23.15 | 12.44 | 102 | 24176 | 124954 | 63339790 |
Pneumonia streptococcal | 22.92 | 12.44 | 12 | 24266 | 1799 | 63462945 |
Premature delivery | 22.44 | 12.44 | 41 | 24237 | 30240 | 63434504 |
Stevens-Johnson syndrome | 21.36 | 12.44 | 36 | 24242 | 24914 | 63439830 |
Monocytosis | 21.15 | 12.44 | 8 | 24270 | 554 | 63464190 |
Resorption bone increased | 20.71 | 12.44 | 10 | 24268 | 1264 | 63463480 |
Neutropenia | 20.49 | 12.44 | 22 | 24256 | 174983 | 63289761 |
Lip swelling | 20.46 | 12.44 | 40 | 24238 | 31023 | 63433721 |
Grip strength decreased | 20.21 | 12.44 | 33 | 24245 | 22254 | 63442490 |
Death neonatal | 20.03 | 12.44 | 9 | 24269 | 966 | 63463778 |
Premature rupture of membranes | 19.93 | 12.44 | 16 | 24262 | 4977 | 63459767 |
Vestibular disorder | 19.60 | 12.44 | 10 | 24268 | 1421 | 63463323 |
Abdominal pain upper | 19.23 | 12.44 | 140 | 24138 | 206304 | 63258440 |
Walking aid user | 19.08 | 12.44 | 22 | 24256 | 10695 | 63454049 |
Corneal neovascularisation | 18.63 | 12.44 | 5 | 24273 | 112 | 63464632 |
Iron deficiency | 18.49 | 12.44 | 18 | 24260 | 7212 | 63457532 |
Oligohydramnios | 18.48 | 12.44 | 17 | 24261 | 6349 | 63458395 |
Mucous stools | 17.78 | 12.44 | 14 | 24264 | 4234 | 63460510 |
Corneal perforation | 17.77 | 12.44 | 7 | 24271 | 541 | 63464203 |
Pharyngeal oedema | 17.74 | 12.44 | 24 | 24254 | 13697 | 63451047 |
Fall | 17.40 | 12.44 | 84 | 24194 | 392250 | 63072494 |
Morbid thoughts | 16.90 | 12.44 | 7 | 24271 | 616 | 63464128 |
Hypotension | 16.84 | 12.44 | 51 | 24227 | 272553 | 63192191 |
Alopecia | 16.31 | 12.44 | 70 | 24208 | 337466 | 63127278 |
Anaemia | 15.99 | 12.44 | 58 | 24220 | 293372 | 63171372 |
Live birth | 15.68 | 12.44 | 32 | 24246 | 25598 | 63439146 |
Prescribed overdose | 15.66 | 12.44 | 38 | 24240 | 34115 | 63430629 |
Infantile haemangioma | 15.52 | 12.44 | 4 | 24274 | 76 | 63464668 |
Starvation ketoacidosis | 15.24 | 12.44 | 4 | 24274 | 82 | 63464662 |
Nodule | 14.99 | 12.44 | 28 | 24250 | 20998 | 63443746 |
Type 2 diabetes mellitus | 14.91 | 12.44 | 56 | 24222 | 63812 | 63400932 |
Pharyngeal swelling | 14.64 | 12.44 | 15 | 24263 | 6389 | 63458355 |
Ergot poisoning | 14.60 | 12.44 | 4 | 24274 | 97 | 63464647 |
Cardiac arrest neonatal | 14.45 | 12.44 | 4 | 24274 | 101 | 63464643 |
Anal candidiasis | 14.38 | 12.44 | 3 | 24275 | 21 | 63464723 |
Drug abuse | 14.18 | 12.44 | 5 | 24273 | 72513 | 63392231 |
Toxicity to various agents | 14.05 | 12.44 | 48 | 24230 | 247202 | 63217542 |
Dysphoria | 13.91 | 12.44 | 13 | 24265 | 4953 | 63459791 |
Stenotrophomonas infection | 13.84 | 12.44 | 9 | 24269 | 2018 | 63462726 |
Drug ineffective | 13.49 | 12.44 | 301 | 23977 | 1044464 | 62420280 |
Delirium | 13.23 | 12.44 | 46 | 24232 | 50495 | 63414249 |
Epidermolysis | 13.10 | 12.44 | 6 | 24272 | 673 | 63464071 |
Jarisch-Herxheimer reaction | 12.88 | 12.44 | 5 | 24273 | 372 | 63464372 |
Disease progression | 12.69 | 12.44 | 17 | 24261 | 122741 | 63342003 |
Febrile neutropenia | 12.66 | 12.44 | 16 | 24262 | 118433 | 63346311 |
Disability | 12.54 | 12.44 | 24 | 24254 | 18323 | 63446421 |
Exposure to SARS-CoV-2 | 12.52 | 12.44 | 8 | 24270 | 1743 | 63463001 |
Product packaging issue | 12.50 | 12.44 | 7 | 24271 | 1199 | 63463545 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 475.82 | 15.35 | 278 | 8461 | 80251 | 34867941 |
Hyphaema | 78.47 | 15.35 | 20 | 8719 | 567 | 34947625 |
Toxic epidermal necrolysis | 75.77 | 15.35 | 54 | 8685 | 21592 | 34926600 |
Drug interaction | 63.70 | 15.35 | 160 | 8579 | 225786 | 34722406 |
Product packaging issue | 62.13 | 15.35 | 17 | 8722 | 637 | 34947555 |
Premature baby | 51.01 | 15.35 | 41 | 8698 | 19592 | 34928600 |
Dystonia | 44.87 | 15.35 | 30 | 8709 | 10815 | 34937377 |
Low birth weight baby | 43.01 | 15.35 | 26 | 8713 | 7879 | 34940313 |
Rhabdomyolysis | 41.91 | 15.35 | 67 | 8672 | 68096 | 34880096 |
Stupor | 40.61 | 15.35 | 18 | 8721 | 2873 | 34945319 |
Acute generalised exanthematous pustulosis | 38.71 | 15.35 | 23 | 8716 | 6753 | 34941439 |
Coagulation time prolonged | 35.27 | 15.35 | 13 | 8726 | 1289 | 34946903 |
Eye pain | 34.72 | 15.35 | 28 | 8711 | 13434 | 34934758 |
Obstruction gastric | 34.56 | 15.35 | 12 | 8727 | 1001 | 34947191 |
Intraocular pressure increased | 32.67 | 15.35 | 19 | 8720 | 5364 | 34942828 |
Pyloric stenosis | 32.33 | 15.35 | 11 | 8728 | 863 | 34947329 |
Brain oedema | 32.00 | 15.35 | 27 | 8712 | 13794 | 34934398 |
Foetal death | 31.37 | 15.35 | 8 | 8731 | 227 | 34947965 |
Product dispensing error | 29.98 | 15.35 | 19 | 8720 | 6255 | 34941937 |
Deafness bilateral | 29.72 | 15.35 | 11 | 8728 | 1103 | 34947089 |
Clonal haematopoiesis | 27.95 | 15.35 | 6 | 8733 | 78 | 34948114 |
Ototoxicity | 27.13 | 15.35 | 12 | 8727 | 1905 | 34946287 |
Learning disorder | 26.30 | 15.35 | 10 | 8729 | 1081 | 34947111 |
Cellulitis enterococcal | 26.18 | 15.35 | 6 | 8733 | 107 | 34948085 |
Foetal arrhythmia | 26.13 | 15.35 | 6 | 8733 | 108 | 34948084 |
Oligohydramnios | 23.42 | 15.35 | 7 | 8732 | 361 | 34947831 |
Onychophagia | 23.37 | 15.35 | 5 | 8734 | 64 | 34948128 |
Torsade de pointes | 22.97 | 15.35 | 17 | 8722 | 7192 | 34941000 |
Caesarean section | 22.68 | 15.35 | 11 | 8728 | 2153 | 34946039 |
Oculogyric crisis | 22.68 | 15.35 | 10 | 8729 | 1576 | 34946616 |
Mixed liver injury | 22.52 | 15.35 | 12 | 8727 | 2861 | 34945331 |
Potentiating drug interaction | 21.14 | 15.35 | 14 | 8725 | 4963 | 34943229 |
Respiratory acidosis | 20.96 | 15.35 | 14 | 8725 | 5036 | 34943156 |
Pathogen resistance | 20.88 | 15.35 | 18 | 8721 | 9464 | 34938728 |
Sepsis neonatal | 20.86 | 15.35 | 6 | 8733 | 270 | 34947922 |
Vasculitic rash | 20.30 | 15.35 | 8 | 8731 | 951 | 34947241 |
Myasthenia gravis crisis | 19.75 | 15.35 | 7 | 8732 | 620 | 34947572 |
Hepatic necrosis | 19.41 | 15.35 | 12 | 8727 | 3782 | 34944410 |
Mycoplasma infection | 18.51 | 15.35 | 6 | 8733 | 405 | 34947787 |
Megacolon | 18.37 | 15.35 | 9 | 8730 | 1801 | 34946391 |
Ischaemic hepatitis | 18.28 | 15.35 | 9 | 8730 | 1819 | 34946373 |
Myoglobinuria | 18.19 | 15.35 | 7 | 8732 | 781 | 34947411 |
Accidental exposure to product | 18.06 | 15.35 | 19 | 8720 | 12783 | 34935409 |
Neonatal disorder | 17.84 | 15.35 | 7 | 8732 | 823 | 34947369 |
Cardio-respiratory arrest neonatal | 17.73 | 15.35 | 3 | 8736 | 9 | 34948183 |
Tricuspid valve disease | 17.67 | 15.35 | 5 | 8734 | 212 | 34947980 |
Foetal exposure during pregnancy | 17.56 | 15.35 | 33 | 8706 | 38068 | 34910124 |
Measles | 17.41 | 15.35 | 5 | 8734 | 224 | 34947968 |
Stevens-Johnson syndrome | 16.82 | 15.35 | 22 | 8717 | 18617 | 34929575 |
Akinesia | 16.77 | 15.35 | 9 | 8730 | 2175 | 34946017 |
Brain herniation | 16.36 | 15.35 | 11 | 8728 | 3997 | 34944195 |
Visual acuity reduced | 16.06 | 15.35 | 20 | 8719 | 16129 | 34932063 |
Hepatic failure | 16.03 | 15.35 | 30 | 8709 | 34501 | 34913691 |
Swelling face | 15.98 | 15.35 | 24 | 8715 | 23081 | 34925111 |
Proteus infection | 15.90 | 15.35 | 7 | 8732 | 1099 | 34947093 |
Exposure during pregnancy | 15.81 | 15.35 | 15 | 8724 | 8919 | 34939273 |
Pneumonia mycoplasmal | 15.73 | 15.35 | 6 | 8733 | 654 | 34947538 |
Pupillary disorder | 15.68 | 15.35 | 5 | 8734 | 320 | 34947872 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 3172.79 | 12.04 | 1678 | 25483 | 297238 | 79419989 |
International normalised ratio fluctuation | 217.28 | 12.04 | 70 | 27091 | 3384 | 79713843 |
Bloody discharge | 175.38 | 12.04 | 52 | 27109 | 1901 | 79715326 |
Lyme disease | 140.19 | 12.04 | 50 | 27111 | 3300 | 79713927 |
Maternal exposure during pregnancy | 111.81 | 12.04 | 181 | 26980 | 136357 | 79580870 |
Drug interaction | 97.78 | 12.04 | 337 | 26824 | 414846 | 79302381 |
Seronegative arthritis | 96.92 | 12.04 | 42 | 27119 | 4650 | 79712577 |
Abortion spontaneous | 96.10 | 12.04 | 80 | 27081 | 29427 | 79687800 |
Product packaging issue | 73.53 | 12.04 | 24 | 27137 | 1209 | 79716018 |
Dislocation of vertebra | 65.42 | 12.04 | 38 | 27123 | 7842 | 79709385 |
Hyphaema | 63.79 | 12.04 | 20 | 27141 | 884 | 79716343 |
Toxic epidermal necrolysis | 58.45 | 12.04 | 74 | 27087 | 44507 | 79672720 |
Exposure during pregnancy | 51.11 | 12.04 | 109 | 27052 | 101023 | 79616204 |
Ototoxicity | 44.73 | 12.04 | 22 | 27139 | 3252 | 79713975 |
Wheezing | 43.89 | 12.04 | 112 | 27049 | 116552 | 79600675 |
Drug abuse | 43.72 | 12.04 | 3 | 27158 | 162688 | 79554539 |
Anaphylactic reaction | 43.17 | 12.04 | 91 | 27070 | 83652 | 79633575 |
Drug intolerance | 42.96 | 12.04 | 191 | 26970 | 263928 | 79453299 |
Stevens-Johnson syndrome | 39.16 | 12.04 | 57 | 27104 | 39109 | 79678118 |
Spinal fusion surgery | 37.59 | 12.04 | 23 | 27138 | 5215 | 79712012 |
Adjustment disorder with depressed mood | 36.78 | 12.04 | 28 | 27133 | 9058 | 79708169 |
Infection | 36.47 | 12.04 | 171 | 26990 | 241541 | 79475686 |
Death | 36.07 | 12.04 | 88 | 27073 | 566426 | 79150801 |
Pneumococcal infection | 35.23 | 12.04 | 13 | 27148 | 945 | 79716282 |
Completed suicide | 35.15 | 12.04 | 20 | 27141 | 245747 | 79471480 |
Wound infection | 34.95 | 12.04 | 42 | 27119 | 23949 | 79693278 |
Spondylitis | 34.53 | 12.04 | 21 | 27140 | 4710 | 79712517 |
Febrile neutropenia | 34.20 | 12.04 | 18 | 27143 | 230981 | 79486246 |
Mass excision | 34.00 | 12.04 | 10 | 27151 | 355 | 79716872 |
Drug tolerance decreased | 33.81 | 12.04 | 31 | 27130 | 12947 | 79704280 |
Rash | 33.51 | 12.04 | 322 | 26839 | 578036 | 79139191 |
Vomiting | 32.09 | 12.04 | 357 | 26804 | 665471 | 79051756 |
Stupor | 31.91 | 12.04 | 23 | 27138 | 6849 | 79710378 |
Anaemia | 31.68 | 12.04 | 65 | 27096 | 444950 | 79272277 |
Ulcerative keratitis | 31.18 | 12.04 | 18 | 27143 | 3671 | 79713556 |
Caesarean section | 30.84 | 12.04 | 29 | 27132 | 12506 | 79704721 |
Purpura senile | 30.33 | 12.04 | 10 | 27151 | 520 | 79716707 |
Tarsal tunnel syndrome | 30.22 | 12.04 | 10 | 27151 | 526 | 79716701 |
Vertigo positional | 30.16 | 12.04 | 17 | 27144 | 3313 | 79713914 |
Necrosis ischaemic | 30.08 | 12.04 | 12 | 27149 | 1078 | 79716149 |
Learning disorder | 29.46 | 12.04 | 10 | 27151 | 569 | 79716658 |
Neutropenia | 27.03 | 12.04 | 35 | 27126 | 287675 | 79429552 |
Breast cancer stage III | 26.64 | 12.04 | 24 | 27137 | 9802 | 79707425 |
Coagulation time prolonged | 26.08 | 12.04 | 14 | 27147 | 2481 | 79714746 |
Intraocular pressure increased | 25.98 | 12.04 | 23 | 27138 | 9182 | 79708045 |
Beta haemolytic streptococcal infection | 25.44 | 12.04 | 13 | 27148 | 2084 | 79715143 |
Hypotension | 25.25 | 12.04 | 72 | 27089 | 440245 | 79276982 |
Torsade de pointes | 25.22 | 12.04 | 32 | 27129 | 19280 | 79697947 |
Benign laryngeal neoplasm | 25.21 | 12.04 | 5 | 27156 | 30 | 79717197 |
Deafness bilateral | 24.93 | 12.04 | 13 | 27148 | 2172 | 79715055 |
Pneumonia streptococcal | 24.83 | 12.04 | 14 | 27147 | 2731 | 79714496 |
Serum sickness-like reaction | 24.77 | 12.04 | 9 | 27152 | 626 | 79716601 |
Premature delivery | 24.69 | 12.04 | 35 | 27126 | 23432 | 79693795 |
Live birth | 24.38 | 12.04 | 31 | 27130 | 18713 | 79698514 |
Product dispensing error | 24.03 | 12.04 | 26 | 27135 | 13237 | 79703990 |
Respiratory acidosis | 23.96 | 12.04 | 24 | 27137 | 11176 | 79706051 |
Urticaria | 23.64 | 12.04 | 125 | 27036 | 185076 | 79532151 |
Grip strength decreased | 23.58 | 12.04 | 33 | 27128 | 21836 | 79695391 |
Type 2 diabetes mellitus | 22.68 | 12.04 | 56 | 27105 | 57066 | 79660161 |
Therapeutic product effect incomplete | 22.66 | 12.04 | 102 | 27059 | 141543 | 79575684 |
Malignant neoplasm progression | 22.60 | 12.04 | 9 | 27152 | 135981 | 79581246 |
Walking aid user | 22.18 | 12.04 | 22 | 27139 | 10126 | 79707101 |
Corneal neovascularisation | 22.12 | 12.04 | 6 | 27155 | 158 | 79717069 |
Acute generalised exanthematous pustulosis | 21.60 | 12.04 | 28 | 27133 | 17226 | 79700001 |
Pharyngeal oedema | 21.30 | 12.04 | 27 | 27134 | 16245 | 79700982 |
Oculogyric crisis | 21.28 | 12.04 | 13 | 27148 | 2939 | 79714288 |
Resorption bone increased | 20.41 | 12.04 | 10 | 27151 | 1465 | 79715762 |
Premature rupture of membranes | 19.77 | 12.04 | 14 | 27147 | 4055 | 79713172 |
Rheumatic fever | 19.58 | 12.04 | 35 | 27126 | 28490 | 79688737 |
Hyponatraemia | 19.58 | 12.04 | 19 | 27142 | 177829 | 79539398 |
Oligohydramnios | 19.56 | 12.04 | 13 | 27148 | 3399 | 79713828 |
Eye pain | 19.55 | 12.04 | 41 | 27120 | 37537 | 79679690 |
Bronchial obstruction | 19.47 | 12.04 | 12 | 27149 | 2756 | 79714471 |
Lip swelling | 19.40 | 12.04 | 43 | 27118 | 40868 | 79676359 |
Pathogen resistance | 19.10 | 12.04 | 24 | 27137 | 14318 | 79702909 |
Swelling face | 18.62 | 12.04 | 60 | 27101 | 71152 | 79646075 |
Rhabdomyolysis | 18.59 | 12.04 | 77 | 27084 | 103054 | 79614173 |
Abdominal rigidity | 18.27 | 12.04 | 12 | 27149 | 3076 | 79714151 |
Ergot poisoning | 18.21 | 12.04 | 5 | 27156 | 138 | 79717089 |
Haemoglobin decreased | 17.94 | 12.04 | 30 | 27131 | 222089 | 79495138 |
Dermatitis allergic | 17.56 | 12.04 | 26 | 27135 | 18104 | 79699123 |
Monocytosis | 17.41 | 12.04 | 8 | 27153 | 1016 | 79716211 |
Dystonia | 16.98 | 12.04 | 28 | 27133 | 21371 | 79695856 |
Morbid thoughts | 15.98 | 12.04 | 7 | 27154 | 795 | 79716432 |
Prescribed overdose | 15.96 | 12.04 | 38 | 27123 | 37845 | 79679382 |
Abdominal pain upper | 15.67 | 12.04 | 130 | 27031 | 223689 | 79493538 |
Vestibular disorder | 15.65 | 12.04 | 10 | 27151 | 2445 | 79714782 |
Fall | 15.43 | 12.04 | 100 | 27061 | 487529 | 79229698 |
Cardio-respiratory arrest | 15.26 | 12.04 | 9 | 27152 | 108501 | 79608726 |
Hip arthroplasty | 15.21 | 12.04 | 36 | 27125 | 35720 | 79681507 |
Disease progression | 14.80 | 12.04 | 25 | 27136 | 184337 | 79532890 |
Confusional state | 14.77 | 12.04 | 57 | 27104 | 317940 | 79399287 |
Asthenia | 14.68 | 12.04 | 108 | 27053 | 511581 | 79205646 |
Amnesia | 14.60 | 12.04 | 51 | 27110 | 63006 | 79654221 |
Swollen joint count increased | 14.31 | 12.04 | 27 | 27134 | 22900 | 79694327 |
Anal candidiasis | 14.26 | 12.04 | 3 | 27158 | 25 | 79717202 |
Blood glucose increased | 14.21 | 12.04 | 11 | 27150 | 114964 | 79602263 |
Platelet count decreased | 14.19 | 12.04 | 28 | 27133 | 194636 | 79522591 |
Toxicity to various agents | 14.08 | 12.04 | 85 | 27076 | 421455 | 79295772 |
Myoglobinuria | 13.87 | 12.04 | 7 | 27154 | 1093 | 79716134 |
Myasthenia gravis crisis | 13.80 | 12.04 | 7 | 27154 | 1104 | 79716123 |
Cardiac arrest neonatal | 13.77 | 12.04 | 3 | 27158 | 30 | 79717197 |
Potentiating drug interaction | 13.77 | 12.04 | 16 | 27145 | 8803 | 79708424 |
Brain oedema | 13.65 | 12.04 | 28 | 27133 | 25235 | 79691992 |
Starvation ketoacidosis | 13.55 | 12.04 | 4 | 27157 | 144 | 79717083 |
Measles | 13.14 | 12.04 | 5 | 27156 | 396 | 79716831 |
Corneal perforation | 13.10 | 12.04 | 6 | 27155 | 757 | 79716470 |
Disability | 13.05 | 12.04 | 22 | 27139 | 17098 | 79700129 |
Iron deficiency | 12.89 | 12.04 | 17 | 27144 | 10637 | 79706590 |
Tricuspid valve disease | 12.78 | 12.04 | 5 | 27156 | 427 | 79716800 |
Liver function test increased | 12.74 | 12.04 | 36 | 27125 | 39737 | 79677490 |
Amniotic cavity infection | 12.64 | 12.04 | 6 | 27155 | 821 | 79716406 |
Platelet count increased | 12.30 | 12.04 | 25 | 27136 | 22381 | 79694846 |
Exposure to SARS-CoV-2 | 12.23 | 12.04 | 8 | 27153 | 2036 | 79715191 |
Sensation of foreign body | 12.12 | 12.04 | 12 | 27149 | 5510 | 79711717 |
Delirium | 12.10 | 12.04 | 59 | 27102 | 84568 | 79632659 |
Corneal deposits | 12.09 | 12.04 | 5 | 27156 | 493 | 79716734 |
Ischaemic hepatitis | 12.06 | 12.04 | 10 | 27151 | 3654 | 79713573 |
None
Source | Code | Description |
---|---|---|
FDA CS | M0028311 | Macrolides |
FDA PE | N0000009982 | Decreased Sebaceous Gland Activity |
MeSH PA | D000900 | Anti-Bacterial Agents |
MeSH PA | D000890 | Anti-Infective Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D005765 | Gastrointestinal Agents |
MeSH PA | D011500 | Protein Synthesis Inhibitors |
FDA EPC | N0000175877 | Macrolide |
FDA EPC | N0000175935 | Macrolide Antimicrobial |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Meningitis | indication | 7180009 | DOID:9471 |
Bacterial septicemia | indication | 10001005 | DOID:0040085 |
Infection of skin AND/OR subcutaneous tissue | indication | 19824006 | |
Bacterial pneumonia | indication | 53084003 | DOID:874 |
Urinary tract infectious disease | indication | 68566005 | |
Hepatic coma | indication | 72836002 | DOID:12550 |
Cholangitis | indication | 82403002 | DOID:9446 |
Infection of bone | indication | 111253001 | |
Infectious disease of abdomen | indication | 128070006 | |
Infectious disorder of joint | indication | 363162000 | |
Preoperative Bowel Preparation | indication | ||
Burn Wound Infections | indication | ||
Acute tuberculosis | off-label use | 25629007 | |
Pulmonary tuberculosis | off-label use | 154283005 | DOID:2957 |
Hypocalcemia | contraindication | 5291005 | |
Parkinsonism | contraindication | 32798002 | |
Dehydration | contraindication | 34095006 | |
Tinnitus | contraindication | 60862001 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Myasthenia gravis | contraindication | 91637004 | DOID:437 |
Pregnancy, function | contraindication | 289908002 | |
Vertigo | contraindication | 399153001 | |
Infant Botulism | contraindication | ||
Disorder of the 8th Cranial Nerve | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 7.61 | Basic |
None
None
None
ID | Source |
---|---|
4017592 | VUID |
N0000145973 | NUI |
4017592 | VANDF |
4017594 | VANDF |
C0014810 | UMLSCUI |
CHEBI:31555 | CHEBI |
CHEBI:42355 | CHEBI |
CHEMBL1200688 | ChEMBL_ID |
D015643 | MESH_DESCRIPTOR_UI |
1014KSJ86F | UNII |
443953 | PUBCHEM_CID |
DB00199 | DRUGBANK_ID |
151373 | RXNORM |
33314 | MMSL |
42396 | MMSL |
4543 | MMSL |
4675 | MMSL |
4677 | MMSL |
4799 | MMSL |
72164 | MMSL |
d00046 | MMSL |
002755 | NDDF |
002757 | NDDF |
12578001 | SNOMEDCT_US |
30427009 | SNOMEDCT_US |
372694001 | SNOMEDCT_US |
C0014806 | UMLSCUI |
39 | INN_ID |
12560 | PUBCHEM_CID |
D004917 | MESH_DESCRIPTOR_UI |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
ERYTHROMYCIN ETHYLSUCCINATE AND SULFISOXAZOLE ACETYL | HUMAN PRESCRIPTION DRUG LABEL | 2 | 21695-690 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | ANDA | 26 sections |
E.E.S 400 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-100 | TABLET | 400 mg | ORAL | ANDA | 27 sections |
E.E.S 400 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-100 | TABLET | 400 mg | ORAL | ANDA | 27 sections |
ERYTHROMYCIN ETHYLSUCCINATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-110 | TABLET | 400 mg | ORAL | ANDA | 26 sections |
ERYTHROMYCIN ETHYLSUCCINATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-110 | TABLET | 400 mg | ORAL | ANDA | 26 sections |
Ery-Ped | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-130 | SUSPENSION | 400 mg | ORAL | NDA | 27 sections |
Ery-Ped | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-130 | SUSPENSION | 400 mg | ORAL | NDA | 27 sections |
Ery-Ped | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-132 | SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
Ery-Ped | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-132 | SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
E.E.S | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-134 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
E.E.S | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-134 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
E.E.S | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-136 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
E.E.S | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24338-136 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
ERYTHROMYCIN ETHYLSUCCINATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52536-130 | SUSPENSION | 400 mg | ORAL | NDA | 27 sections |
ERYTHROMYCIN ETHYLSUCCINATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52536-132 | SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52536-134 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | NDA | 28 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52536-136 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | NDA | 28 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-0018 | TABLET | 400 mg | ORAL | ANDA | 13 sections |
ERYTHROMYCIN ETHYLSUCCINATE AND SULFISOXAZOLE ACETYL | HUMAN PRESCRIPTION DRUG LABEL | 2 | 54868-0971 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | ANDA | 26 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 62559-440 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | ANDA | 23 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 62559-440 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | ANDA | 23 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 62559-630 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | ANDA | 22 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 62559-631 | GRANULE, FOR SUSPENSION | 400 mg | ORAL | ANDA | 22 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 63629-2500 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 63629-2500 | GRANULE, FOR SUSPENSION | 200 mg | ORAL | NDA | 27 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 69238-1503 | SUSPENSION | 200 mg | ORAL | ANDA | 19 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 69238-1503 | SUSPENSION | 200 mg | ORAL | ANDA | 19 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 69238-1504 | SUSPENSION | 400 mg | ORAL | ANDA | 19 sections |
Erythromycin Ethylsuccinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 69238-1504 | SUSPENSION | 400 mg | ORAL | ANDA | 19 sections |
Erythromycin ethylsuccinate | Human Prescription Drug Label | 1 | 71209-102 | FOR SUSPENSION | 200 mg | ORAL | ANDA | 22 sections |