Molfile
Inchi
Smiles
Synonyms:
-
eptifibatide
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eftifibatide
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integrelin
-
integrilin
-
intrifiban
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Cyclic peptide that acts as a platelet glycoprotein IIB-IIIA antagonist, reversibly inhibiting the binding of FIBRINOGEN; VON WILLEBRAND FACTOR; and other adhesive molecules to the GPIIB-IIIA RECEPTORS of platelets. It is used in the management of UNSTABLE ANGINA and in patients undergoing coronary ANGIOPLASTY and stenting procedures.
- Molecular weight: 831.97
- Formula: C35H49N11O9S2
- CLOGP: -2.21
- LIPINSKI: 3
- HAC: 20
- HDO: 11
- TPSA: 323.89
- ALOGS: -3.67
- ROTB: 10
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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