epicillin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 1025 26774-90-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • epicillin
  • dexacilina
  • dexacillin
  • dihydroampicillin
  • spectacillin
semisynthetic penicillin type antibiotic; minor descriptor (75-85); on-line & Index Medicus search AMPICILLIN/AA (75-85); RN given refers to (2s(2alpha,5alpha,6beta(S*)))-isomer
  • Molecular weight: 351.42
  • Formula: C16H21N3O4S
  • CLOGP: -1.09
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 112.73
  • ALOGS: -2.65
  • ROTB: 4

Drug dosage:

DoseUnitRoute
2 g O
2 g P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01CA07 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Penicillins with extended spectrum
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.79 acidic
pKa2 7.56 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04020 KEGG_DRUG
C0059424 UMLSCUI
CHEBI:58974 CHEBI
CHEMBL2104266 ChEMBL_ID
DB13300 DRUGBANK_ID
C100212 MESH_SUPPLEMENTAL_RECORD_UI
71392 PUBCHEM_CID
10804 IUPHAR_LIGAND_ID
2996 INN_ID
3LU1L73C8Y UNII
34983009 SNOMEDCT_US

Pharmaceutical products:

None