emetine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1001 483-18-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • emetine dihydrochloride
  • emetine hydrochloride
  • methylcephaeline
  • ipecine
  • emetine
  • (-)-Emetine
  • cephaeline methyl ether
  • emetin
The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.
  • Molecular weight: 480.65
  • Formula: C29H40N2O4
  • CLOGP: 4.75
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 1
  • TPSA: 52.19
  • ALOGS: -5.23
  • ROTB: 7

Drug dosage:

DoseUnitRoute
60 mg P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

emetine