emepronium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| quaternary ammonium compounds | 1000 | 27892-33-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A muscarinic antagonist used mainly in the treatment of urinary syndromes. It is incompletely absorbed from the gastrointestinal tract and does not cross the blood-brain barrier.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.50 | g | O |
| 75 | mg | P |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Hosey CM, Chan R, Benet LZ |
| BA (Bioavailability) | 1 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
| S (Water solubility) | 62.50 mg/mL | Bocci G, Oprea TI, Benet LZ |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A03CA30 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS Synthetic anticholinergic agents in combination with psycholeptics |
| ATC | G04BD01 | GENITO URINARY SYSTEM AND SEX HORMONES UROLOGICALS UROLOGICALS Drugs for urinary frequency and incontinence |
| ATC | N05CX05 | NERVOUS SYSTEM PSYCHOLEPTICS HYPNOTICS AND SEDATIVES Hypnotics and sedatives in combination, excl. barbiturates |
| MeSH PA | D018678 | Cholinergic Agents |
| MeSH PA | D018680 | Cholinergic Antagonists |
| MeSH PA | D018727 | Muscarinic Antagonists |
| MeSH PA | D018377 | Neurotransmitter Agents |
| MeSH PA | D010276 | Parasympatholytics |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D064804 | Urological Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07224 | KEGG_DRUG |
| 3614-30-0 | SECONDARY_CAS_RN |
| CHEBI:135169 | CHEBI |
| CHEMBL2110805 | ChEMBL_ID |
| CHEMBL2106122 | ChEMBL_ID |
| C046238 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB13505 | DRUGBANK_ID |
| 04QQ8SWA4U | UNII |
| 34055 | PUBCHEM_CID |
| 23944 | RXNORM |
| 005136 | NDDF |
| 005137 | NDDF |
| 005138 | NDDF |
| 398715005 | SNOMEDCT_US |
| 421158004 | SNOMEDCT_US |
| 421500009 | SNOMEDCT_US |
| C0013954 | UMLSCUI |
| D004629 | MESH_DESCRIPTOR_UI |
| CHEMBL2109087 | ChEMBL_ID |
| 2414 | INN_ID |
Pharmaceutical products:
None