clofibrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
clofibrate derivatives, peroxisome proliferator activated receptor-alpha(PPAR-alpha) agonists 694 637-07-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • clofibrate
  • ticlobran
  • xyduril
  • p-chlorophenoxyisobutyric acid ethyl ester
  • lipavil
  • lipavlon
  • lipomid
  • liprinal
  • miscleron
  • misclerone
A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
  • Molecular weight: 242.70
  • Formula: C12H15ClO3
  • CLOGP: 3.68
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 0
  • TPSA: 35.53
  • ALOGS: -3.92
  • ROTB: 5
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

clofibrate