etofibrate indications/contra

Stem definitionDrug idCAS RN
clofibrate derivatives 1106 31637-97-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • etofibrate hydrochloride
  • etofibrate HCl
  • etofibrate
  • ethofibrate
  • tricerol
analog of clofibrate with nicotinic acid substituted on the 2-carbon of the ethyl ester group; structure; RN given refers to parent cpd
  • Molecular weight: 363.79
  • Formula: C18H18ClNO5
  • CLOGP: 3.75
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 0
  • TPSA: 74.72
  • ALOGS: -4.01
  • ROTB: 9

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC C10AB09 CARDIOVASCULAR SYSTEM
LIPID MODIFYING AGENTS
LIPID MODIFYING AGENTS, PLAIN
Fibrates
MeSH PA D000924 Anticholesteremic Agents
MeSH PA D000963 Antimetabolites
MeSH PA D000960 Hypolipidemic Agents
MeSH PA D057847 Lipid Regulating Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.03 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0059869 UMLSCUI
D07187 KEGG_DRUG
23TF67G79M UNII
3616 INN_ID
24609 RXNORM
006004 NDDF
703414000 SNOMEDCT_US
703900008 SNOMEDCT_US
CHEMBL358150 ChEMBL_ID
65777 PUBCHEM_CID
C009746 MESH_SUPPLEMENTAL_RECORD_UI
DB08983 DRUGBANK_ID
CHEBI:135535 CHEBI

Pharmaceutical products:

None