Beta-lactamase

Description:

Description
  • Accession: Q59401
  • Swissprot: Q59401_ENTCL
  • Organism: Enterobacter cloacae
  • Target class: Enzyme

Drug Relations:

clavulanic acid
A beta-lactam antibiotic produced by the actinobacterium Streptomyces clavuligerus. It is a suicide inhibitor of bacterial beta-lactamase enzymes. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase. Bioactivity details MOA
tazobactam
A penicillanic acid and sulfone derivative and potent BETA-LACTAMASE inhibitor that enhances the activity of other anti-bacterial agents against beta-lactamase producing bacteria. Bioactivity details MOA