docarpamine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
dopaminergic agents dopamine derivatives used as cardiac stimulant/antihypertensives/diuretics 938 74639-40-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • docarpamine
  • tanadopa
a dopamine prodrug; RN given refers to (S)-isomer; structure given in first source
  • Molecular weight: 470.54
  • Formula: C21H30N2O8S
  • CLOGP: 0.05
  • LIPINSKI: 0
  • HAC: 10
  • HDO: 2
  • TPSA: 129.26
  • ALOGS: -4.94
  • ROTB: 16

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D015259 Dopamine Agents
MeSH PA D018491 Dopamine Agonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.85 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01903 KEGG_DRUG
C0075755 UMLSCUI
CHEBI:31513 CHEBI
CHEMBL2106351 ChEMBL_ID
C052143 MESH_SUPPLEMENTAL_RECORD_UI
71137 PUBCHEM_CID
6258 INN_ID
RPQ57D8S72 UNII
DB00988 DRUGBANK_ID
008206 NDDF

Pharmaceutical products:

None