diphemanil Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
915 62-97-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • diphemanil
  • biphemanil
  • diphemanil methosulfate
  • diphemanil methyl sulfate
  • diphemanil metilsulfate
  • diphenmanil methylsulfate
  • diphenmethanil
  • diphenmethanil methylsulfate
  • diphemanil methylsulfate
  • Molecular weight: 278.42
  • Formula: C20H24N
  • CLOGP: 0.13
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA:
  • ALOGS: -5.93
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
May 17, 1976 FDA SCHERING

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC A03AB15 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Synthetic anticholinergics, quaternary ammonium compounds
ATC A03CA08 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS
Synthetic anticholinergic agents in combination with psycholeptics
CHEBI has role CHEBI:48876 muscarinic antagonist
CHEBI has role CHEBI:50370 parasympatholytic
CHEBI has role CHEBI:35523 bronchodilator agent
MeSH PA D018927 Anti-Asthmatic Agents
MeSH PA D001993 Bronchodilator Agents
MeSH PA D010276 Parasympatholytics
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D019141 Respiratory System Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Muscarinic acetylcholine receptor M3 GPCR ANTAGONIST DRUGBANK CHEMBL
Muscarinic acetylcholine receptor M1 GPCR ANTAGONIST CHEMBL CHEMBL

External reference:

IDSource
C0301371 UMLSCUI
D06878 KEGG_DRUG
1842003 SNOMEDCT_US
373748003 SNOMEDCT_US
89782 RXNORM
CHEBI:59782 CHEBI
Q26TX1UD0W UNII
15394-62-4 SECONDARY_CAS_RN
342 INN_ID
6127 PUBCHEM_CID
CHEMBL1200880 ChEMBL_ID
CHEMBL1201340 ChEMBL_ID
DB13720 DRUGBANK_ID
C028209 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None