diphemanil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	915	62-97-5

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

diphemanil
biphemanil
diphemanil methosulfate
diphemanil methyl sulfate
diphemanil metilsulfate
diphenmanil methylsulfate
diphenmethanil
diphenmethanil methylsulfate
diphemanil methylsulfate

Molecular weight: 278.42
Formula: C20H24N
CLOGP: 0.13
LIPINSKI: 0
HAC: 1
HDO: 0
TPSA:
ALOGS: -5.93
ROTB: 2

Status: OFM

Legend:
OFP - off patent
OFM - off market
ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
May 17, 1976	FDA	SCHERING

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A03AB15	ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS Synthetic anticholinergics, quaternary ammonium compounds
ATC	A03CA08	ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS Synthetic anticholinergic agents in combination with psycholeptics
MeSH PA	D018927	Anti-Asthmatic Agents
MeSH PA	D001993	Bronchodilator Agents
MeSH PA	D010276	Parasympatholytics
MeSH PA	D018373	Peripheral Nervous System Agents
MeSH PA	D019141	Respiratory System Agents
CHEBI has role	CHEBI:35523	bronchodilator
CHEBI has role	CHEBI:48876	muscarinic antagonists
CHEBI has role	CHEBI:50370	parasympatholytics

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Muscarinic acetylcholine receptor M1	GPCR	P11229	ACM1_HUMAN	ANTAGONIST				CHEMBL	CHEMBL
Muscarinic acetylcholine receptor M3	GPCR	P20309	ACM3_HUMAN	ANTAGONIST				DRUGBANK	CHEMBL

External reference:

ID	Source
D06878	KEGG_DRUG
23364	RXNORM
C0301371	UMLSCUI
CHEBI:93636	CHEBI
CHEMBL1201340	ChEMBL_ID
DB13720	DRUGBANK_ID
CHEMBL1200880	ChEMBL_ID
C028209	MESH_SUPPLEMENTAL_RECORD_UI
6127	PUBCHEM_CID
Q26TX1UD0W	UNII
001736	NDDF
1842003	SNOMEDCT_US
29184007	SNOMEDCT_US
373748003	SNOMEDCT_US
342	INN_ID
15394-62-4	SECONDARY_CAS_RN

Pharmaceutical products:

None