Stem definition | Drug id | CAS RN |
---|---|---|
opioid receptor antagonists/agonists, morphinan derivates | 842 | 125-71-3 |
Dose | Unit | Route |
---|---|---|
40 | mg | O |
90 | mg | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 15 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.19 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 4.88 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 11 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
fu (Fraction unbound in plasma) | 0.24 % | Kawashima H, Watanabe R, Esaki T, Kuroda M, Nagao C, Natsume-Kitatani Y, Ohashi R, Komura H, Mizuguchi K |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 3, 1957 | FDA | ANI PHARMS |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Toxicity to various agents | 2354.78 | 10.23 | 5663 | 492864 | 241587 | 62748908 |
Completed suicide | 2266.17 | 10.23 | 4084 | 494443 | 141589 | 62848906 |
Infusion related reaction | 862.75 | 10.23 | 4015 | 494512 | 241506 | 62748989 |
Exposure to toxic agent | 862.21 | 10.23 | 541 | 497986 | 5046 | 62985449 |
Sinusitis | 686.21 | 10.23 | 3553 | 494974 | 223100 | 62767395 |
Muscle injury | 560.97 | 10.23 | 1441 | 497086 | 63904 | 62926591 |
Folliculitis | 547.17 | 10.23 | 1495 | 497032 | 68822 | 62921673 |
Acute hepatic failure | 501.64 | 10.23 | 668 | 497859 | 17659 | 62972836 |
Irritable bowel syndrome | 485.57 | 10.23 | 1588 | 496939 | 80824 | 62909671 |
Lower respiratory tract infection | 466.32 | 10.23 | 2167 | 496360 | 130140 | 62860355 |
Intentional overdose | 455.09 | 10.23 | 1449 | 497078 | 72703 | 62917792 |
Blood pressure fluctuation | 421.07 | 10.23 | 1044 | 497483 | 45273 | 62945222 |
Blister | 397.14 | 10.23 | 2042 | 496485 | 127772 | 62862723 |
Overdose | 381.55 | 10.23 | 1852 | 496675 | 113226 | 62877269 |
Sleep disorder due to general medical condition, insomnia type | 380.35 | 10.23 | 1084 | 497443 | 51133 | 62939362 |
Duodenal ulcer perforation | 375.09 | 10.23 | 1517 | 497010 | 85692 | 62904803 |
Helicobacter infection | 373.93 | 10.23 | 1582 | 496945 | 91203 | 62899292 |
Ill-defined disorder | 370.00 | 10.23 | 1445 | 497082 | 80310 | 62910185 |
Injection site pain | 367.77 | 10.23 | 288 | 498239 | 129512 | 62860983 |
Intentional product misuse | 349.97 | 10.23 | 1164 | 497363 | 59753 | 62930742 |
Anti-cyclic citrullinated peptide antibody positive | 336.79 | 10.23 | 1801 | 496726 | 114411 | 62876084 |
Pericarditis | 336.78 | 10.23 | 1972 | 496555 | 129607 | 62860888 |
Impaired healing | 316.32 | 10.23 | 1617 | 496910 | 100925 | 62889570 |
Nasopharyngitis | 314.74 | 10.23 | 3215 | 495312 | 251042 | 62739453 |
Rheumatoid arthritis | 307.78 | 10.23 | 3196 | 495331 | 250623 | 62739872 |
Metabolic acidosis | 301.77 | 10.23 | 908 | 497619 | 44161 | 62946334 |
Hepatic enzyme increased | 295.68 | 10.23 | 2650 | 495877 | 199678 | 62790817 |
Hepatic cytolysis | 286.24 | 10.23 | 468 | 498059 | 14939 | 62975556 |
Product dose omission issue | 280.32 | 10.23 | 924 | 497603 | 233389 | 62757106 |
Joint swelling | 249.67 | 10.23 | 3783 | 494744 | 323883 | 62666612 |
Therapeutic product effect decreased | 234.21 | 10.23 | 2433 | 496094 | 190754 | 62799741 |
Analgesic drug level increased | 231.23 | 10.23 | 173 | 498354 | 2199 | 62988296 |
Hepatotoxicity | 220.05 | 10.23 | 716 | 497811 | 36325 | 62954170 |
Intentional product use issue | 218.99 | 10.23 | 1736 | 496791 | 126156 | 62864339 |
Device expulsion | 218.63 | 10.23 | 14 | 498513 | 34908 | 62955587 |
Injection site erythema | 216.62 | 10.23 | 200 | 498327 | 82974 | 62907521 |
Gastrointestinal disorder | 214.71 | 10.23 | 1763 | 496764 | 129476 | 62861019 |
Diarrhoea | 213.37 | 10.23 | 4149 | 494378 | 711217 | 62279278 |
Synovitis | 208.85 | 10.23 | 2316 | 496211 | 184602 | 62805893 |
Anion gap | 206.91 | 10.23 | 129 | 498398 | 1188 | 62989307 |
Medication error | 192.63 | 10.23 | 868 | 497659 | 51416 | 62939079 |
Stomatitis | 192.36 | 10.23 | 1797 | 496730 | 136928 | 62853567 |
Hypersensitivity | 189.51 | 10.23 | 3290 | 495237 | 289395 | 62701100 |
Discomfort | 182.92 | 10.23 | 2065 | 496462 | 165309 | 62825186 |
Weight increased | 182.90 | 10.23 | 2970 | 495557 | 257822 | 62732673 |
Hand deformity | 182.33 | 10.23 | 1985 | 496542 | 157472 | 62833023 |
Wrong technique in product usage process | 179.45 | 10.23 | 136 | 498391 | 62204 | 62928291 |
Depressed level of consciousness | 173.59 | 10.23 | 953 | 497574 | 61125 | 62929370 |
Psoriasis | 171.95 | 10.23 | 260 | 498267 | 86697 | 62903798 |
Body temperature increased | 169.49 | 10.23 | 659 | 497868 | 36533 | 62953962 |
Anaemia | 161.33 | 10.23 | 1499 | 497028 | 291931 | 62698564 |
Swelling | 161.16 | 10.23 | 3047 | 495480 | 272331 | 62718164 |
Drug ineffective | 159.87 | 10.23 | 6650 | 491877 | 1038115 | 61952380 |
Wound | 156.68 | 10.23 | 1965 | 496562 | 161298 | 62829197 |
Suicide attempt | 151.20 | 10.23 | 906 | 497621 | 60012 | 62930483 |
Sedation complication | 146.67 | 10.23 | 331 | 498196 | 13491 | 62977004 |
Injection site reaction | 145.09 | 10.23 | 147 | 498380 | 58377 | 62932118 |
Infusion site pain | 143.62 | 10.23 | 371 | 498156 | 16498 | 62973997 |
Blood pressure systolic abnormal | 138.09 | 10.23 | 317 | 498210 | 13069 | 62977426 |
Blood pressure diastolic abnormal | 135.51 | 10.23 | 331 | 498196 | 14211 | 62976284 |
Heart rate decreased | 134.54 | 10.23 | 710 | 497817 | 44850 | 62945645 |
Injection site bruising | 130.44 | 10.23 | 84 | 498443 | 41826 | 62948669 |
Injection site pruritus | 129.11 | 10.23 | 99 | 498428 | 45017 | 62945478 |
Rheumatic fever | 125.36 | 10.23 | 669 | 497858 | 42442 | 62948053 |
Creatinine renal clearance decreased | 125.03 | 10.23 | 345 | 498182 | 15963 | 62974532 |
Respiratory arrest | 124.79 | 10.23 | 548 | 497979 | 32097 | 62958398 |
Rheumatoid factor positive | 123.32 | 10.23 | 1106 | 497421 | 83300 | 62907195 |
Peripheral swelling | 122.68 | 10.23 | 2842 | 495685 | 263100 | 62727395 |
Coagulopathy | 120.10 | 10.23 | 395 | 498132 | 20149 | 62970346 |
Cardio-respiratory arrest | 119.59 | 10.23 | 844 | 497683 | 59115 | 62931380 |
Infusion site extravasation | 118.90 | 10.23 | 257 | 498270 | 10169 | 62980326 |
Infection | 118.34 | 10.23 | 2489 | 496038 | 226684 | 62763811 |
Blood pressure diastolic decreased | 118.22 | 10.23 | 420 | 498107 | 22286 | 62968209 |
Neutropenia | 118.07 | 10.23 | 846 | 497681 | 174159 | 62816336 |
Infusion site swelling | 117.39 | 10.23 | 246 | 498281 | 9524 | 62980971 |
Confusional state | 112.71 | 10.23 | 2538 | 495989 | 233842 | 62756653 |
Disease progression | 112.37 | 10.23 | 538 | 497989 | 122220 | 62868275 |
Ear pain | 111.58 | 10.23 | 570 | 497957 | 35548 | 62954947 |
Blood pressure systolic increased | 110.72 | 10.23 | 694 | 497833 | 46703 | 62943792 |
Poisoning deliberate | 110.62 | 10.23 | 261 | 498266 | 10957 | 62979538 |
Throat irritation | 101.26 | 10.23 | 572 | 497955 | 37075 | 62953420 |
Injection site swelling | 100.19 | 10.23 | 136 | 498391 | 47436 | 62943059 |
Cardiac failure congestive | 100.02 | 10.23 | 380 | 498147 | 92053 | 62898442 |
Swollen joint count increased | 99.77 | 10.23 | 552 | 497975 | 35502 | 62954993 |
Drug abuse | 99.24 | 10.23 | 937 | 497590 | 71581 | 62918914 |
Oxygen saturation decreased | 96.25 | 10.23 | 1092 | 497435 | 87493 | 62903002 |
Myocardial infarction | 96.03 | 10.23 | 430 | 498097 | 99463 | 62891032 |
Blood pressure increased | 94.93 | 10.23 | 1794 | 496733 | 160268 | 62830227 |
Hospitalisation | 94.52 | 10.23 | 346 | 498181 | 84735 | 62905760 |
Osteonecrosis of jaw | 93.16 | 10.23 | 83 | 498444 | 35040 | 62955455 |
Muscle spasticity | 92.73 | 10.23 | 378 | 498149 | 21416 | 62969079 |
Nausea | 91.50 | 10.23 | 5639 | 492888 | 848832 | 62141663 |
Drug resistance | 91.10 | 10.23 | 33 | 498494 | 22900 | 62967595 |
Blood calcium decreased | 89.93 | 10.23 | 429 | 498098 | 26022 | 62964473 |
Therapy cessation | 89.51 | 10.23 | 65 | 498462 | 30392 | 62960103 |
Infusion site erythema | 89.46 | 10.23 | 247 | 498280 | 11432 | 62979063 |
Neuropathy peripheral | 86.96 | 10.23 | 529 | 497998 | 113138 | 62877357 |
Cardiac failure | 84.91 | 10.23 | 385 | 498142 | 88757 | 62901738 |
Drug hypersensitivity | 84.68 | 10.23 | 1827 | 496700 | 308860 | 62681635 |
Glossodynia | 84.08 | 10.23 | 1917 | 496610 | 176959 | 62813536 |
Infusion site pruritus | 83.31 | 10.23 | 161 | 498366 | 5874 | 62984621 |
Product substitution issue | 83.13 | 10.23 | 13 | 498514 | 15983 | 62974512 |
Malignant neoplasm progression | 82.90 | 10.23 | 347 | 498180 | 81774 | 62908721 |
Pancytopenia | 82.88 | 10.23 | 435 | 498092 | 96498 | 62893997 |
Poisoning | 81.51 | 10.23 | 265 | 498262 | 13435 | 62977060 |
Dizziness | 80.53 | 10.23 | 2668 | 495859 | 427257 | 62563238 |
Pyroglutamic acidosis | 79.63 | 10.23 | 54 | 498473 | 581 | 62989914 |
White blood cell count decreased | 79.20 | 10.23 | 704 | 497823 | 138400 | 62852095 |
Drug interaction | 78.61 | 10.23 | 1295 | 497232 | 227836 | 62762659 |
Acute lung injury | 78.19 | 10.23 | 78 | 498449 | 1493 | 62989002 |
Pruritus | 78.02 | 10.23 | 3527 | 495000 | 357926 | 62632569 |
Device dislocation | 77.99 | 10.23 | 53 | 498474 | 25652 | 62964843 |
Respiratory depression | 77.76 | 10.23 | 261 | 498266 | 13454 | 62977041 |
Product quality issue | 75.05 | 10.23 | 103 | 498424 | 35762 | 62954733 |
Decreased appetite | 74.10 | 10.23 | 1457 | 497070 | 249595 | 62740900 |
Sopor | 73.78 | 10.23 | 41 | 498486 | 22123 | 62968372 |
Hepatic failure | 73.49 | 10.23 | 506 | 498021 | 35150 | 62955345 |
Bone marrow failure | 73.24 | 10.23 | 73 | 498454 | 29217 | 62961278 |
Arthropathy | 72.46 | 10.23 | 2383 | 496144 | 232409 | 62758086 |
Device malfunction | 72.12 | 10.23 | 25 | 498502 | 17832 | 62972663 |
Feeling abnormal | 71.89 | 10.23 | 781 | 497746 | 147611 | 62842884 |
Therapeutic product effect incomplete | 71.59 | 10.23 | 632 | 497895 | 124424 | 62866071 |
Coma | 71.52 | 10.23 | 797 | 497730 | 63567 | 62926928 |
Abortion spontaneous | 71.31 | 10.23 | 166 | 498361 | 47029 | 62943466 |
Injection site warmth | 71.18 | 10.23 | 16 | 498511 | 15179 | 62975316 |
Pemphigus | 70.84 | 10.23 | 1917 | 496610 | 181809 | 62808686 |
Pyrexia | 70.67 | 10.23 | 4437 | 494090 | 466041 | 62524454 |
Paraesthesia | 70.23 | 10.23 | 841 | 497686 | 156125 | 62834370 |
Mobility decreased | 70.16 | 10.23 | 1339 | 497188 | 119820 | 62870675 |
Diabetes mellitus | 69.47 | 10.23 | 216 | 498311 | 55594 | 62934901 |
Neoplasm progression | 69.06 | 10.23 | 112 | 498415 | 36316 | 62954179 |
COVID-19 | 68.61 | 10.23 | 1259 | 497268 | 111844 | 62878651 |
Suspected suicide | 68.25 | 10.23 | 156 | 498371 | 6412 | 62984083 |
Poor venous access | 68.18 | 10.23 | 263 | 498264 | 14522 | 62975973 |
Orthostatic hypotension | 68.05 | 10.23 | 502 | 498025 | 35658 | 62954837 |
Exposure via ingestion | 66.12 | 10.23 | 97 | 498430 | 2812 | 62987683 |
Muscle spasms | 65.95 | 10.23 | 847 | 497680 | 155303 | 62835192 |
Hepatic necrosis | 65.79 | 10.23 | 141 | 498386 | 5546 | 62984949 |
Contusion | 64.98 | 10.23 | 1590 | 496937 | 148454 | 62842041 |
Cerebrovascular accident | 64.02 | 10.23 | 541 | 497986 | 107483 | 62883012 |
Contraindicated product administered | 63.59 | 10.23 | 2195 | 496332 | 215453 | 62775042 |
Renal impairment | 63.06 | 10.23 | 420 | 498107 | 87935 | 62902560 |
Surgery | 62.98 | 10.23 | 116 | 498411 | 35796 | 62954699 |
Product storage error | 62.04 | 10.23 | 20 | 498507 | 14936 | 62975559 |
Cognitive disorder | 61.95 | 10.23 | 691 | 497836 | 55124 | 62935371 |
Pyroglutamate increased | 61.34 | 10.23 | 40 | 498487 | 401 | 62990094 |
Night sweats | 60.56 | 10.23 | 618 | 497909 | 48196 | 62942299 |
Bone pain | 59.51 | 10.23 | 224 | 498303 | 54417 | 62936078 |
Injection site rash | 59.49 | 10.23 | 37 | 498490 | 18772 | 62971723 |
Accidental overdose | 59.31 | 10.23 | 349 | 498178 | 22960 | 62967535 |
Palmar-plantar erythrodysaesthesia syndrome | 59.13 | 10.23 | 56 | 498471 | 22959 | 62967536 |
Infusion site bruising | 58.84 | 10.23 | 107 | 498420 | 3725 | 62986770 |
Vision blurred | 58.78 | 10.23 | 451 | 498076 | 91473 | 62899022 |
Red blood cell sedimentation rate abnormal | 58.41 | 10.23 | 42 | 498485 | 19740 | 62970755 |
Electric shock | 57.49 | 10.23 | 61 | 498466 | 1259 | 62989236 |
Blood cholesterol increased | 56.08 | 10.23 | 1044 | 497483 | 92988 | 62897507 |
Respiratory disorder | 55.98 | 10.23 | 510 | 498017 | 38572 | 62951923 |
Device difficult to use | 55.09 | 10.23 | 16 | 498511 | 12780 | 62977715 |
Sedation | 54.86 | 10.23 | 505 | 498022 | 38304 | 62952191 |
No adverse event | 54.59 | 10.23 | 156 | 498371 | 41249 | 62949246 |
Infusion site haemorrhage | 54.19 | 10.23 | 122 | 498405 | 4964 | 62985531 |
Therapy interrupted | 54.15 | 10.23 | 108 | 498419 | 32347 | 62958148 |
Ear pruritus | 53.78 | 10.23 | 105 | 498422 | 3860 | 62986635 |
Anion gap abnormal | 53.66 | 10.23 | 36 | 498491 | 380 | 62990115 |
Seizure | 53.24 | 10.23 | 727 | 497800 | 131907 | 62858588 |
Injection site urticaria | 53.00 | 10.23 | 22 | 498505 | 14051 | 62976444 |
Hyperkalaemia | 52.87 | 10.23 | 232 | 498295 | 53971 | 62936524 |
Injection site haemorrhage | 52.73 | 10.23 | 68 | 498459 | 24246 | 62966249 |
Heart rate increased | 52.68 | 10.23 | 1036 | 497491 | 93202 | 62897293 |
Type 2 diabetes mellitus | 52.61 | 10.23 | 748 | 497779 | 63120 | 62927375 |
Leukopenia | 51.41 | 10.23 | 375 | 498152 | 76915 | 62913580 |
Platelet count decreased | 50.84 | 10.23 | 625 | 497902 | 115497 | 62874998 |
Dehydration | 50.83 | 10.23 | 1007 | 497520 | 172347 | 62818148 |
Injection site mass | 50.79 | 10.23 | 43 | 498484 | 18613 | 62971882 |
Blood parathyroid hormone decreased | 50.78 | 10.23 | 8 | 498519 | 9783 | 62980712 |
Arthralgia | 50.65 | 10.23 | 5160 | 493367 | 564550 | 62425945 |
Device issue | 50.06 | 10.23 | 68 | 498459 | 23713 | 62966782 |
Thrombocytopenia | 49.62 | 10.23 | 861 | 497666 | 150296 | 62840199 |
Multiple sclerosis relapse | 49.44 | 10.23 | 204 | 498323 | 48274 | 62942221 |
Drug intolerance | 49.05 | 10.23 | 2926 | 495601 | 305735 | 62684760 |
Depression | 48.52 | 10.23 | 1173 | 497354 | 195319 | 62795176 |
Heart rate irregular | 47.88 | 10.23 | 321 | 498206 | 22100 | 62968395 |
Oedema peripheral | 47.71 | 10.23 | 1128 | 497399 | 188383 | 62802112 |
Epistaxis | 47.34 | 10.23 | 355 | 498172 | 72370 | 62918125 |
Transient ischaemic attack | 47.06 | 10.23 | 146 | 498381 | 37607 | 62952888 |
Liver injury | 46.77 | 10.23 | 701 | 497826 | 59819 | 62930676 |
Schizoaffective disorder | 46.71 | 10.23 | 93 | 498434 | 3469 | 62987026 |
Hypokalaemia | 46.47 | 10.23 | 556 | 497971 | 103248 | 62887247 |
Hyponatraemia | 46.12 | 10.23 | 610 | 497917 | 111290 | 62879205 |
Blood pressure diastolic increased | 46.11 | 10.23 | 178 | 498349 | 9832 | 62980663 |
Product prescribing error | 46.02 | 10.23 | 85 | 498442 | 26204 | 62964291 |
Drug use disorder | 45.96 | 10.23 | 113 | 498414 | 4871 | 62985624 |
Systemic lupus erythematosus | 45.94 | 10.23 | 2043 | 496484 | 206875 | 62783620 |
Jaundice cholestatic | 45.69 | 10.23 | 144 | 498383 | 7180 | 62983315 |
Gastrointestinal haemorrhage | 45.67 | 10.23 | 412 | 498115 | 80764 | 62909731 |
Foetal exposure during pregnancy | 45.47 | 10.23 | 116 | 498411 | 31846 | 62958649 |
Accidental exposure to product | 45.03 | 10.23 | 92 | 498435 | 27313 | 62963182 |
Dry skin | 44.94 | 10.23 | 262 | 498265 | 56625 | 62933870 |
Myalgia | 43.91 | 10.23 | 848 | 497679 | 145681 | 62844814 |
Suicidal ideation | 43.89 | 10.23 | 298 | 498229 | 62123 | 62928372 |
Myelosuppression | 43.88 | 10.23 | 74 | 498453 | 23629 | 62966866 |
Dyspnoea exertional | 43.85 | 10.23 | 285 | 498242 | 60017 | 62930478 |
Hypocalcaemia | 43.66 | 10.23 | 117 | 498410 | 31596 | 62958899 |
Granuloma skin | 43.52 | 10.23 | 7 | 498520 | 8430 | 62982065 |
Basal cell carcinoma | 42.65 | 10.23 | 98 | 498429 | 27893 | 62962602 |
Breast cancer stage I | 42.42 | 10.23 | 3 | 498524 | 6886 | 62983609 |
Rash pruritic | 42.29 | 10.23 | 285 | 498242 | 59514 | 62930981 |
Full blood count abnormal | 42.18 | 10.23 | 119 | 498408 | 31598 | 62958897 |
Hyperlipidaemia | 42.17 | 10.23 | 55 | 498472 | 19516 | 62970979 |
Hypomania | 41.85 | 10.23 | 127 | 498400 | 6203 | 62984292 |
Urine leukocyte esterase positive | 41.70 | 10.23 | 89 | 498438 | 3490 | 62987005 |
Hypercalcaemia | 41.68 | 10.23 | 101 | 498426 | 28221 | 62962274 |
Unevaluable event | 41.49 | 10.23 | 235 | 498292 | 51151 | 62939344 |
Full blood count decreased | 41.38 | 10.23 | 89 | 498438 | 25935 | 62964560 |
Interstitial lung disease | 41.35 | 10.23 | 300 | 498227 | 61608 | 62928887 |
Body temperature decreased | 41.07 | 10.23 | 287 | 498240 | 20032 | 62970463 |
Cytokine release syndrome | 40.83 | 10.23 | 221 | 498306 | 14093 | 62976402 |
Methaemoglobinaemia | 40.64 | 10.23 | 70 | 498457 | 2333 | 62988162 |
Myelodysplastic syndrome | 40.48 | 10.23 | 43 | 498484 | 16711 | 62973784 |
Posterior reversible encephalopathy syndrome | 40.27 | 10.23 | 46 | 498481 | 17299 | 62973196 |
Syncope | 40.02 | 10.23 | 664 | 497863 | 116721 | 62873774 |
Mucosal inflammation | 39.87 | 10.23 | 211 | 498316 | 46717 | 62943778 |
Breast cancer female | 39.76 | 10.23 | 29 | 498498 | 13530 | 62976965 |
Tremor | 39.71 | 10.23 | 765 | 497762 | 131474 | 62859021 |
Atrial fibrillation | 39.69 | 10.23 | 660 | 497867 | 115976 | 62874519 |
Visual acuity reduced | 39.62 | 10.23 | 69 | 498458 | 21757 | 62968738 |
Drug withdrawal syndrome | 39.22 | 10.23 | 98 | 498429 | 27096 | 62963399 |
Weight fluctuation | 39.18 | 10.23 | 167 | 498360 | 9652 | 62980843 |
Osteonecrosis | 38.92 | 10.23 | 84 | 498443 | 24446 | 62966049 |
Incorrect drug administration rate | 38.87 | 10.23 | 92 | 498435 | 3870 | 62986625 |
Pain in extremity | 38.73 | 10.23 | 2168 | 496359 | 329318 | 62661177 |
Loss of consciousness | 38.38 | 10.23 | 674 | 497853 | 117447 | 62873048 |
Skin necrosis | 38.17 | 10.23 | 32 | 498495 | 13918 | 62976577 |
Haematotoxicity | 38.08 | 10.23 | 13 | 498514 | 9363 | 62981132 |
Renal failure | 38.02 | 10.23 | 672 | 497855 | 116980 | 62873515 |
Therapeutic response decreased | 37.86 | 10.23 | 305 | 498222 | 61220 | 62929275 |
Urine abnormality | 37.54 | 10.23 | 131 | 498396 | 6888 | 62983607 |
Acute kidney injury | 37.49 | 10.23 | 1688 | 496839 | 261727 | 62728768 |
Crystal urine present | 37.37 | 10.23 | 55 | 498472 | 1599 | 62988896 |
Blood glucose increased | 37.34 | 10.23 | 449 | 498078 | 83307 | 62907188 |
Injection site induration | 37.12 | 10.23 | 13 | 498514 | 9213 | 62981282 |
Inappropriate schedule of product administration | 37.02 | 10.23 | 1074 | 497453 | 102891 | 62887604 |
Administration site swelling | 36.31 | 10.23 | 48 | 498479 | 1259 | 62989236 |
Memory impairment | 36.12 | 10.23 | 588 | 497939 | 103670 | 62886825 |
Injury | 35.95 | 10.23 | 790 | 497737 | 72457 | 62918038 |
Coronary artery disease | 35.73 | 10.23 | 132 | 498395 | 32245 | 62958250 |
Panniculitis | 35.18 | 10.23 | 23 | 498504 | 11362 | 62979133 |
Hypotension | 35.14 | 10.23 | 2539 | 495988 | 270065 | 62720430 |
Underdose | 35.06 | 10.23 | 105 | 498422 | 27351 | 62963144 |
Epilepsy | 34.93 | 10.23 | 103 | 498424 | 26962 | 62963533 |
Anticipatory anxiety | 34.84 | 10.23 | 46 | 498481 | 1205 | 62989290 |
White blood cells urine positive | 34.58 | 10.23 | 104 | 498423 | 5054 | 62985441 |
Vaginal haemorrhage | 34.47 | 10.23 | 106 | 498421 | 27381 | 62963114 |
Macular degeneration | 34.35 | 10.23 | 317 | 498210 | 24059 | 62966436 |
Fall | 34.27 | 10.23 | 2634 | 495893 | 389700 | 62600795 |
Hypertensive crisis | 33.93 | 10.23 | 42 | 498485 | 15244 | 62975251 |
Pulmonary hypertension | 33.77 | 10.23 | 163 | 498364 | 36960 | 62953535 |
Gastrooesophageal reflux disease | 33.59 | 10.23 | 538 | 497989 | 95101 | 62895394 |
Therapeutic response unexpected | 33.42 | 10.23 | 60 | 498467 | 18699 | 62971796 |
Metastases to bone | 33.33 | 10.23 | 72 | 498455 | 20947 | 62969548 |
Respiratory rate increased | 33.22 | 10.23 | 202 | 498325 | 13446 | 62977049 |
Femur fracture | 33.15 | 10.23 | 192 | 498335 | 41564 | 62948931 |
Diabetic ketoacidosis | 32.71 | 10.23 | 70 | 498457 | 20435 | 62970060 |
Alanine aminotransferase increased | 32.67 | 10.23 | 1056 | 497471 | 102714 | 62887781 |
Extrapyramidal disorder | 32.20 | 10.23 | 34 | 498493 | 13250 | 62977245 |
Spinal stenosis | 32.10 | 10.23 | 42 | 498485 | 14883 | 62975612 |
Drug-induced liver injury | 31.90 | 10.23 | 468 | 498059 | 39754 | 62950741 |
Genital haemorrhage | 31.87 | 10.23 | 9 | 498518 | 7323 | 62983172 |
Burning sensation | 31.54 | 10.23 | 274 | 498253 | 54133 | 62936362 |
Device use error | 31.54 | 10.23 | 4 | 498523 | 5757 | 62984738 |
Skin exfoliation | 31.19 | 10.23 | 204 | 498323 | 42898 | 62947597 |
Multiple drug therapy | 30.84 | 10.23 | 80 | 498447 | 3566 | 62986929 |
Lactic acidosis | 30.42 | 10.23 | 176 | 498351 | 38111 | 62952384 |
Haemorrhage | 30.40 | 10.23 | 319 | 498208 | 60703 | 62929792 |
International normalised ratio increased | 30.34 | 10.23 | 523 | 498004 | 45902 | 62944593 |
Breast cancer | 30.16 | 10.23 | 239 | 498288 | 48144 | 62942351 |
Fluid retention | 30.15 | 10.23 | 311 | 498216 | 59375 | 62931120 |
Urticaria | 30.04 | 10.23 | 1591 | 496936 | 164211 | 62826284 |
Infusion site mass | 29.57 | 10.23 | 56 | 498471 | 2012 | 62988483 |
Palpitations | 29.54 | 10.23 | 667 | 497860 | 112103 | 62878392 |
Administration site pain | 29.54 | 10.23 | 35 | 498492 | 819 | 62989676 |
Urinary sediment present | 29.47 | 10.23 | 58 | 498469 | 2145 | 62988350 |
Pathogen resistance | 29.44 | 10.23 | 7 | 498520 | 6391 | 62984104 |
Ageusia | 29.15 | 10.23 | 39 | 498488 | 13689 | 62976806 |
Ascites | 28.85 | 10.23 | 194 | 498333 | 40534 | 62949961 |
Neurotoxicity | 28.80 | 10.23 | 56 | 498471 | 16934 | 62973561 |
Complication associated with device | 28.75 | 10.23 | 56 | 498471 | 16922 | 62973573 |
Gestational diabetes | 28.72 | 10.23 | 15 | 498512 | 8381 | 62982114 |
Infusion site nodule | 28.63 | 10.23 | 46 | 498481 | 1446 | 62989049 |
Disease recurrence | 28.55 | 10.23 | 118 | 498409 | 27912 | 62962583 |
Electrolyte imbalance | 28.45 | 10.23 | 73 | 498454 | 20003 | 62970492 |
Chronic kidney disease | 28.42 | 10.23 | 224 | 498303 | 45174 | 62945321 |
Injection site discolouration | 28.40 | 10.23 | 13 | 498514 | 7835 | 62982660 |
Metastases to lung | 28.34 | 10.23 | 35 | 498492 | 12715 | 62977780 |
Cytomegalovirus infection | 28.31 | 10.23 | 78 | 498449 | 20874 | 62969621 |
Heavy menstrual bleeding | 28.08 | 10.23 | 61 | 498466 | 17712 | 62972783 |
Cerebral infarction | 27.97 | 10.23 | 95 | 498432 | 23798 | 62966697 |
Transplant rejection | 27.96 | 10.23 | 26 | 498501 | 10754 | 62979741 |
Facet joint syndrome | 27.88 | 10.23 | 177 | 498350 | 11961 | 62978534 |
Hypothyroidism | 27.79 | 10.23 | 208 | 498319 | 42424 | 62948071 |
Irritability | 27.77 | 10.23 | 141 | 498386 | 31553 | 62958942 |
Metastases to liver | 27.67 | 10.23 | 94 | 498433 | 23545 | 62966950 |
Second primary malignancy | 27.52 | 10.23 | 14 | 498513 | 7939 | 62982556 |
Intervertebral discitis | 27.48 | 10.23 | 71 | 498456 | 3157 | 62987338 |
Hyperglycaemia | 27.42 | 10.23 | 204 | 498323 | 41663 | 62948832 |
Toxicologic test abnormal | 27.37 | 10.23 | 31 | 498496 | 690 | 62989805 |
Prothrombin time shortened | 27.27 | 10.23 | 53 | 498474 | 1942 | 62988553 |
Infusion site irritation | 27.15 | 10.23 | 35 | 498492 | 895 | 62989600 |
Drug dose omission by device | 27.11 | 10.23 | 3 | 498524 | 4798 | 62985697 |
Respiratory failure | 27.10 | 10.23 | 601 | 497926 | 101257 | 62889238 |
Disturbance in attention | 27.00 | 10.23 | 182 | 498345 | 38007 | 62952488 |
Blood potassium decreased | 26.94 | 10.23 | 206 | 498321 | 41820 | 62948675 |
Premature delivery | 26.94 | 10.23 | 134 | 498393 | 30147 | 62960348 |
Thrombotic microangiopathy | 26.77 | 10.23 | 26 | 498501 | 10535 | 62979960 |
Soft tissue disorder | 26.72 | 10.23 | 86 | 498441 | 4336 | 62986159 |
Complication of device insertion | 26.65 | 10.23 | 13 | 498514 | 7551 | 62982944 |
Sepsis | 26.54 | 10.23 | 959 | 497568 | 152164 | 62838331 |
Labelled drug-drug interaction medication error | 26.53 | 10.23 | 40 | 498487 | 13359 | 62977136 |
Neutrophil percentage increased | 26.37 | 10.23 | 66 | 498461 | 2877 | 62987618 |
COVID-19 pneumonia | 26.02 | 10.23 | 196 | 498331 | 14013 | 62976482 |
Cardiac disorder | 25.99 | 10.23 | 264 | 498263 | 50552 | 62939943 |
Anion gap increased | 25.72 | 10.23 | 50 | 498477 | 1832 | 62988663 |
Fear of injection | 25.72 | 10.23 | 12 | 498515 | 7152 | 62983343 |
Pulmonary arterial hypertension | 25.60 | 10.23 | 91 | 498436 | 22486 | 62968009 |
Rash | 25.59 | 10.23 | 4885 | 493642 | 555986 | 62434509 |
Acute myocardial infarction | 25.34 | 10.23 | 148 | 498379 | 31976 | 62958519 |
Specific gravity urine decreased | 25.33 | 10.23 | 31 | 498496 | 751 | 62989744 |
Thrombosis | 25.23 | 10.23 | 357 | 498170 | 64398 | 62926097 |
Fibromyalgia | 25.21 | 10.23 | 818 | 497709 | 79602 | 62910893 |
Gait disturbance | 25.20 | 10.23 | 1178 | 497349 | 182000 | 62808495 |
Bursitis | 25.19 | 10.23 | 420 | 498107 | 36621 | 62953874 |
Withdrawal syndrome | 25.16 | 10.23 | 77 | 498450 | 19920 | 62970575 |
Septic shock | 25.03 | 10.23 | 370 | 498157 | 66259 | 62924236 |
Dysgeusia | 25.01 | 10.23 | 240 | 498287 | 46470 | 62944025 |
Akathisia | 25.00 | 10.23 | 21 | 498506 | 9125 | 62981370 |
Complication of device removal | 24.93 | 10.23 | 5 | 498522 | 5137 | 62985358 |
Skin ulcer | 24.85 | 10.23 | 217 | 498310 | 42828 | 62947667 |
Red blood cells urine positive | 24.83 | 10.23 | 67 | 498460 | 3059 | 62987436 |
Polyneuropathy | 24.81 | 10.23 | 48 | 498479 | 14541 | 62975954 |
Lymphocyte percentage decreased | 24.74 | 10.23 | 65 | 498462 | 2920 | 62987575 |
Sensitivity to weather change | 24.65 | 10.23 | 13 | 498514 | 7224 | 62983271 |
Pneumocystis jirovecii pneumonia | 24.36 | 10.23 | 61 | 498466 | 16853 | 62973642 |
Musculoskeletal disorder | 24.22 | 10.23 | 82 | 498445 | 20562 | 62969933 |
Post transplant lymphoproliferative disorder | 24.17 | 10.23 | 5 | 498522 | 5026 | 62985469 |
Hepatic cirrhosis | 24.04 | 10.23 | 106 | 498421 | 24628 | 62965867 |
Sexual dysfunction | 23.93 | 10.23 | 3 | 498524 | 4356 | 62986139 |
Tardive dyskinesia | 23.89 | 10.23 | 19 | 498508 | 8483 | 62982012 |
Incorrect dose administered by device | 23.85 | 10.23 | 3 | 498524 | 4345 | 62986150 |
Systemic infection | 23.74 | 10.23 | 4 | 498523 | 4656 | 62985839 |
Aphasia | 23.47 | 10.23 | 157 | 498370 | 32843 | 62957652 |
Ear infection | 23.37 | 10.23 | 426 | 498101 | 37787 | 62952708 |
Lymphocyte count decreased | 23.19 | 10.23 | 350 | 498177 | 29907 | 62960588 |
Intermenstrual bleeding | 23.18 | 10.23 | 17 | 498510 | 7909 | 62982586 |
Ventricular extrasystoles | 23.03 | 10.23 | 35 | 498492 | 11652 | 62978843 |
Infusion site discomfort | 23.00 | 10.23 | 41 | 498486 | 1405 | 62989090 |
Neuroleptic malignant syndrome | 22.91 | 10.23 | 37 | 498490 | 12019 | 62978476 |
Renal disorder | 22.89 | 10.23 | 158 | 498369 | 32816 | 62957679 |
Hypocoagulable state | 22.87 | 10.23 | 37 | 498490 | 1170 | 62989325 |
Multiple allergies | 22.85 | 10.23 | 186 | 498341 | 13616 | 62976879 |
Hepatitis acute | 22.85 | 10.23 | 136 | 498391 | 8984 | 62981511 |
Thinking abnormal | 22.84 | 10.23 | 30 | 498497 | 10613 | 62979882 |
Product complaint | 22.79 | 10.23 | 41 | 498486 | 12768 | 62977727 |
Deep vein thrombosis postoperative | 22.64 | 10.23 | 160 | 498367 | 11209 | 62979286 |
Hepatic encephalopathy | 22.59 | 10.23 | 159 | 498368 | 11123 | 62979372 |
Infusion site rash | 22.56 | 10.23 | 49 | 498478 | 1945 | 62988550 |
Vital capacity decreased | 22.52 | 10.23 | 45 | 498482 | 1683 | 62988812 |
Dermatitis atopic | 22.35 | 10.23 | 26 | 498501 | 9698 | 62980797 |
Device breakage | 22.33 | 10.23 | 35 | 498492 | 11507 | 62978988 |
Laboratory test abnormal | 22.31 | 10.23 | 122 | 498405 | 26790 | 62963705 |
Cardiotoxicity | 22.30 | 10.23 | 20 | 498507 | 8418 | 62982077 |
Carpal tunnel syndrome | 22.23 | 10.23 | 86 | 498441 | 20731 | 62969764 |
Schizophrenia | 22.17 | 10.23 | 144 | 498383 | 9808 | 62980687 |
Insurance issue | 22.07 | 10.23 | 101 | 498426 | 6020 | 62984475 |
Product adhesion issue | 22.04 | 10.23 | 5 | 498522 | 4714 | 62985781 |
Sputum culture positive | 22.00 | 10.23 | 51 | 498476 | 2116 | 62988379 |
Metastases to lymph nodes | 21.97 | 10.23 | 19 | 498508 | 8139 | 62982356 |
Abdominal distension | 21.92 | 10.23 | 515 | 498012 | 86100 | 62904395 |
Cardiac arrest | 21.88 | 10.23 | 912 | 497615 | 91633 | 62898862 |
Drug ineffective for unapproved indication | 21.82 | 10.23 | 167 | 498360 | 33896 | 62956599 |
Forced expiratory volume decreased | 21.78 | 10.23 | 6 | 498521 | 4962 | 62985533 |
Right ventricular failure | 21.76 | 10.23 | 66 | 498461 | 17122 | 62973373 |
Substance abuse | 21.75 | 10.23 | 85 | 498442 | 4722 | 62985773 |
Brain oedema | 21.75 | 10.23 | 188 | 498339 | 14007 | 62976488 |
Rheumatoid nodule | 21.62 | 10.23 | 66 | 498461 | 17089 | 62973406 |
Analgesic drug level above therapeutic | 21.62 | 10.23 | 15 | 498512 | 168 | 62990327 |
Skin burning sensation | 21.56 | 10.23 | 42 | 498485 | 12692 | 62977803 |
Drug level increased | 21.49 | 10.23 | 273 | 498254 | 22463 | 62968032 |
Dyskinesia | 21.40 | 10.23 | 155 | 498372 | 31847 | 62958648 |
Disturbance in social behaviour | 21.31 | 10.23 | 3 | 498524 | 3990 | 62986505 |
Multiple-drug resistance | 21.29 | 10.23 | 7 | 498520 | 5163 | 62985332 |
Body temperature fluctuation | 21.28 | 10.23 | 52 | 498475 | 2233 | 62988262 |
Brain death | 21.23 | 10.23 | 67 | 498460 | 3343 | 62987152 |
Abnormal dreams | 21.21 | 10.23 | 31 | 498496 | 10485 | 62980010 |
Generalised tonic-clonic seizure | 21.16 | 10.23 | 137 | 498390 | 28879 | 62961616 |
Acute myeloid leukaemia | 20.89 | 10.23 | 67 | 498460 | 17080 | 62973415 |
Low density lipoprotein increased | 20.81 | 10.23 | 12 | 498515 | 6345 | 62984150 |
Treatment noncompliance | 20.74 | 10.23 | 190 | 498337 | 37135 | 62953360 |
Product preparation error | 20.67 | 10.23 | 11 | 498516 | 6081 | 62984414 |
Acidosis | 20.59 | 10.23 | 155 | 498372 | 11078 | 62979417 |
Low turnover osteopathy | 20.44 | 10.23 | 4 | 498523 | 4181 | 62986314 |
Anti-cyclic citrullinated peptide antibody | 20.41 | 10.23 | 106 | 498421 | 6652 | 62983843 |
Status epilepticus | 20.37 | 10.23 | 57 | 498470 | 15176 | 62975319 |
Neutrophil count decreased | 20.24 | 10.23 | 316 | 498211 | 56090 | 62934405 |
Fracture | 20.22 | 10.23 | 82 | 498445 | 19502 | 62970993 |
Upper respiratory tract infection | 20.19 | 10.23 | 812 | 497715 | 81235 | 62909260 |
Skin toxicity | 20.10 | 10.23 | 6 | 498521 | 4708 | 62985787 |
Blood pH decreased | 20.10 | 10.23 | 55 | 498472 | 2532 | 62987963 |
Pharyngeal paraesthesia | 20.09 | 10.23 | 47 | 498480 | 1962 | 62988533 |
Sleep apnoea syndrome | 20.02 | 10.23 | 140 | 498387 | 28993 | 62961502 |
Cerebral haemorrhage | 19.99 | 10.23 | 150 | 498377 | 30579 | 62959916 |
Unintended pregnancy | 19.76 | 10.23 | 12 | 498515 | 6167 | 62984328 |
Angina unstable | 19.75 | 10.23 | 16 | 498511 | 7079 | 62983416 |
Caesarean section | 19.75 | 10.23 | 68 | 498459 | 16964 | 62973531 |
Lip dry | 19.73 | 10.23 | 197 | 498330 | 15273 | 62975222 |
Hepatitis cholestatic | 19.49 | 10.23 | 106 | 498421 | 6772 | 62983723 |
Hallucination, auditory | 19.45 | 10.23 | 45 | 498482 | 12779 | 62977716 |
Pain in jaw | 19.45 | 10.23 | 233 | 498294 | 43263 | 62947232 |
Transplant dysfunction | 19.37 | 10.23 | 7 | 498520 | 4865 | 62985630 |
Hypomagnesaemia | 19.31 | 10.23 | 139 | 498388 | 28598 | 62961897 |
Unresponsive to stimuli | 19.31 | 10.23 | 373 | 498154 | 33443 | 62957052 |
Amenorrhoea | 19.24 | 10.23 | 30 | 498497 | 9884 | 62980611 |
Ductus arteriosus premature closure | 19.20 | 10.23 | 18 | 498509 | 318 | 62990177 |
Blood creatine increased | 19.15 | 10.23 | 91 | 498436 | 5510 | 62984985 |
Iron deficiency anaemia | 19.15 | 10.23 | 86 | 498441 | 19883 | 62970612 |
Inappropriate antidiuretic hormone secretion | 19.12 | 10.23 | 60 | 498467 | 15402 | 62975093 |
Administration site bruise | 19.11 | 10.23 | 20 | 498507 | 406 | 62990089 |
X-ray abnormal | 19.09 | 10.23 | 119 | 498408 | 7991 | 62982504 |
Infusion site urticaria | 18.96 | 10.23 | 40 | 498487 | 1556 | 62988939 |
Disorientation | 18.94 | 10.23 | 208 | 498319 | 39244 | 62951251 |
Deep vein thrombosis | 18.85 | 10.23 | 507 | 498020 | 83293 | 62907202 |
Brain stem glioma | 18.71 | 10.23 | 14 | 498513 | 178 | 62990317 |
Drug eruption | 18.70 | 10.23 | 140 | 498387 | 28554 | 62961941 |
Plasma cell myeloma | 18.58 | 10.23 | 186 | 498341 | 35719 | 62954776 |
Prothrombin time ratio decreased | 18.53 | 10.23 | 22 | 498505 | 516 | 62989979 |
Macular oedema | 18.33 | 10.23 | 4 | 498523 | 3873 | 62986622 |
Dystonia | 18.26 | 10.23 | 52 | 498475 | 13767 | 62976728 |
Adjustment disorder with depressed mood | 18.26 | 10.23 | 140 | 498387 | 10064 | 62980431 |
Galactorrhoea | 18.25 | 10.23 | 5 | 498522 | 4150 | 62986345 |
Pregnancy with contraceptive device | 18.23 | 10.23 | 7 | 498520 | 4687 | 62985808 |
Ankylosing spondylitis | 18.21 | 10.23 | 34 | 498493 | 10440 | 62980055 |
Blood immunoglobulin E increased | 18.13 | 10.23 | 4 | 498523 | 3845 | 62986650 |
Rheumatoid lung | 18.13 | 10.23 | 4 | 498523 | 3844 | 62986651 |
Liver transplant | 18.09 | 10.23 | 49 | 498478 | 2242 | 62988253 |
Haemophagocytic lymphohistiocytosis | 18.04 | 10.23 | 35 | 498492 | 10592 | 62979903 |
Malaise | 18.04 | 10.23 | 2930 | 495597 | 413024 | 62577471 |
Tinnitus | 17.85 | 10.23 | 186 | 498341 | 35442 | 62955053 |
Hypothermia | 17.83 | 10.23 | 174 | 498353 | 13407 | 62977088 |
Atypical femur fracture | 17.79 | 10.23 | 10 | 498517 | 5362 | 62985133 |
Pulmonary embolism | 17.76 | 10.23 | 742 | 497785 | 115942 | 62874553 |
Ventricular fibrillation | 17.72 | 10.23 | 42 | 498485 | 11825 | 62978670 |
Oral discomfort | 17.71 | 10.23 | 28 | 498499 | 9173 | 62981322 |
Pneumonia streptococcal | 17.71 | 10.23 | 42 | 498485 | 1769 | 62988726 |
Haemoglobin decreased | 17.60 | 10.23 | 948 | 497579 | 144537 | 62845958 |
Coagulation factor X level decreased | 17.52 | 10.23 | 10 | 498517 | 77 | 62990418 |
Therapeutic response shortened | 17.46 | 10.23 | 156 | 498371 | 11732 | 62978763 |
Flatulence | 17.45 | 10.23 | 181 | 498346 | 34521 | 62955974 |
Wound infection | 17.33 | 10.23 | 250 | 498277 | 21160 | 62969335 |
Diplopia | 17.32 | 10.23 | 112 | 498415 | 23616 | 62966879 |
Cardiomyopathy | 17.31 | 10.23 | 75 | 498452 | 17509 | 62972986 |
Mitral valve incompetence | 17.26 | 10.23 | 87 | 498440 | 19507 | 62970988 |
Reversible airways obstruction | 17.24 | 10.23 | 42 | 498485 | 1800 | 62988695 |
Torsade de pointes | 17.09 | 10.23 | 51 | 498476 | 13300 | 62977195 |
Aplasia pure red cell | 16.92 | 10.23 | 7 | 498520 | 4480 | 62986015 |
Peripheral venous disease | 16.89 | 10.23 | 191 | 498336 | 15286 | 62975209 |
Post cholecystectomy syndrome | 16.88 | 10.23 | 19 | 498508 | 420 | 62990075 |
Dysphoria | 16.80 | 10.23 | 9 | 498518 | 4957 | 62985538 |
Dyspnoea | 16.78 | 10.23 | 4783 | 493744 | 656530 | 62333965 |
Colorectal cancer | 16.75 | 10.23 | 4 | 498523 | 3641 | 62986854 |
Renal failure neonatal | 16.70 | 10.23 | 13 | 498514 | 176 | 62990319 |
Uterine perforation | 16.68 | 10.23 | 18 | 498509 | 6945 | 62983550 |
Invasive ductal breast carcinoma | 16.65 | 10.23 | 18 | 498509 | 6940 | 62983555 |
Pleural effusion | 16.54 | 10.23 | 582 | 497945 | 92628 | 62897867 |
Tricuspid valve incompetence | 16.53 | 10.23 | 59 | 498468 | 14562 | 62975933 |
Postmortem blood drug level increased | 16.50 | 10.23 | 22 | 498505 | 582 | 62989913 |
SARS-CoV-2 test positive | 16.41 | 10.23 | 114 | 498413 | 7942 | 62982553 |
Febrile bone marrow aplasia | 16.39 | 10.23 | 20 | 498507 | 7305 | 62983190 |
Cryopyrin associated periodic syndrome | 16.33 | 10.23 | 17 | 498510 | 343 | 62990152 |
Device leakage | 16.28 | 10.23 | 19 | 498508 | 7077 | 62983418 |
Ischaemic stroke | 16.24 | 10.23 | 79 | 498448 | 17878 | 62972617 |
Deafness | 16.24 | 10.23 | 79 | 498448 | 17878 | 62972617 |
Ketoacidosis | 16.24 | 10.23 | 7 | 498520 | 4371 | 62986124 |
Coagulation factor VII level decreased | 16.23 | 10.23 | 10 | 498517 | 90 | 62990405 |
Aspergillus infection | 16.18 | 10.23 | 24 | 498503 | 8069 | 62982426 |
Mood swings | 16.09 | 10.23 | 81 | 498446 | 18167 | 62972328 |
Post procedural pulmonary embolism | 16.00 | 10.23 | 15 | 498512 | 265 | 62990230 |
Joint range of motion decreased | 15.98 | 10.23 | 350 | 498177 | 32078 | 62958417 |
Skin lesion | 15.96 | 10.23 | 159 | 498368 | 30562 | 62959933 |
Haematuria | 15.95 | 10.23 | 149 | 498378 | 29008 | 62961487 |
Abdominal pain lower | 15.93 | 10.23 | 127 | 498400 | 25551 | 62964944 |
Congestive cardiomyopathy | 15.93 | 10.23 | 15 | 498512 | 6167 | 62984328 |
Red cell distribution width increased | 15.92 | 10.23 | 139 | 498388 | 10385 | 62980110 |
Pancreatic carcinoma | 15.86 | 10.23 | 22 | 498505 | 7606 | 62982889 |
Vein collapse | 15.84 | 10.23 | 29 | 498498 | 1015 | 62989480 |
Lupus-like syndrome | 15.82 | 10.23 | 64 | 498463 | 15231 | 62975264 |
Vertigo | 15.74 | 10.23 | 354 | 498173 | 59533 | 62930962 |
Autoimmune disorder | 15.71 | 10.23 | 205 | 498322 | 16972 | 62973523 |
Embedded device | 15.66 | 10.23 | 4 | 498523 | 3479 | 62987016 |
Skin discolouration | 15.65 | 10.23 | 206 | 498321 | 37622 | 62952873 |
Cardiac failure acute | 15.62 | 10.23 | 32 | 498495 | 9491 | 62981004 |
Thyroid neoplasm | 15.60 | 10.23 | 6 | 498521 | 4013 | 62986482 |
Blood urine present | 15.57 | 10.23 | 184 | 498343 | 14885 | 62975610 |
Dysphagia | 15.52 | 10.23 | 554 | 497973 | 88031 | 62902464 |
Maternal exposure timing unspecified | 15.45 | 10.23 | 102 | 498425 | 6985 | 62983510 |
Movement disorder | 15.43 | 10.23 | 103 | 498424 | 21558 | 62968937 |
Product residue present | 15.34 | 10.23 | 6 | 498521 | 3973 | 62986522 |
Polycystic ovaries | 15.28 | 10.23 | 8 | 498519 | 4463 | 62986032 |
Aspartate aminotransferase | 15.27 | 10.23 | 18 | 498509 | 419 | 62990076 |
Ventricular arrhythmia | 15.19 | 10.23 | 65 | 498462 | 3763 | 62986732 |
Dislocation of vertebra | 15.19 | 10.23 | 118 | 498409 | 8517 | 62981978 |
Gastrointestinal pain | 15.08 | 10.23 | 34 | 498493 | 9742 | 62980753 |
Mood altered | 15.05 | 10.23 | 62 | 498465 | 14681 | 62975814 |
Asthenia | 15.04 | 10.23 | 2717 | 495810 | 380887 | 62609608 |
Band neutrophil count increased | 15.02 | 10.23 | 17 | 498510 | 378 | 62990117 |
Epstein-Barr virus infection | 15.02 | 10.23 | 25 | 498502 | 8025 | 62982470 |
Device failure | 15.01 | 10.23 | 15 | 498512 | 5996 | 62984499 |
Enthesopathy | 14.95 | 10.23 | 28 | 498499 | 8586 | 62981909 |
Aspartate aminotransferase increased | 14.90 | 10.23 | 859 | 497668 | 89418 | 62901077 |
Osmolar gap | 14.87 | 10.23 | 10 | 498517 | 106 | 62990389 |
Prothrombin time prolonged | 14.83 | 10.23 | 127 | 498400 | 9437 | 62981058 |
Clostridium test positive | 14.81 | 10.23 | 57 | 498470 | 3144 | 62987351 |
Sudden infant death syndrome | 14.75 | 10.23 | 15 | 498512 | 294 | 62990201 |
Impaired quality of life | 14.68 | 10.23 | 57 | 498470 | 13726 | 62976769 |
Bacterial test | 14.62 | 10.23 | 30 | 498497 | 1144 | 62989351 |
Joint stiffness | 14.54 | 10.23 | 236 | 498291 | 41633 | 62948862 |
Cardiovascular disorder | 14.49 | 10.23 | 46 | 498481 | 11766 | 62978729 |
Speech disorder | 14.44 | 10.23 | 228 | 498299 | 40401 | 62950094 |
Dysphonia | 14.42 | 10.23 | 275 | 498252 | 47339 | 62943156 |
Dysstasia | 14.41 | 10.23 | 102 | 498425 | 21064 | 62969431 |
Cytopenia | 14.36 | 10.23 | 45 | 498482 | 11556 | 62978939 |
Sensory disturbance | 14.27 | 10.23 | 57 | 498470 | 13615 | 62976880 |
Therapy change | 14.26 | 10.23 | 16 | 498511 | 6065 | 62984430 |
Oral pruritus | 14.25 | 10.23 | 45 | 498482 | 2246 | 62988249 |
Head injury | 14.14 | 10.23 | 142 | 498385 | 27254 | 62963241 |
Congestive hepatopathy | 14.11 | 10.23 | 53 | 498474 | 2889 | 62987606 |
Tendonitis | 14.11 | 10.23 | 93 | 498434 | 19522 | 62970973 |
Metastases to central nervous system | 14.09 | 10.23 | 54 | 498473 | 13051 | 62977444 |
White coat hypertension | 13.96 | 10.23 | 22 | 498505 | 680 | 62989815 |
Haemoglobin urine present | 13.95 | 10.23 | 24 | 498503 | 799 | 62989696 |
Osteoarthritis | 13.94 | 10.23 | 609 | 497918 | 94734 | 62895761 |
Abortion induced | 13.94 | 10.23 | 38 | 498489 | 10204 | 62980291 |
Drug screen positive | 13.93 | 10.23 | 61 | 498466 | 3568 | 62986927 |
Device related thrombosis | 13.92 | 10.23 | 38 | 498489 | 1747 | 62988748 |
Vaginal flatulence | 13.91 | 10.23 | 57 | 498470 | 3236 | 62987259 |
Small for dates baby | 13.91 | 10.23 | 6 | 498521 | 3745 | 62986750 |
Hip fracture | 13.91 | 10.23 | 156 | 498371 | 29318 | 62961177 |
Granulocyte count increased | 13.90 | 10.23 | 25 | 498502 | 863 | 62989632 |
Pre-eclampsia | 13.89 | 10.23 | 32 | 498495 | 9101 | 62981394 |
Administration site erythema | 13.89 | 10.23 | 23 | 498504 | 742 | 62989753 |
Drug level below therapeutic | 13.79 | 10.23 | 75 | 498452 | 4791 | 62985704 |
Dysarthria | 13.77 | 10.23 | 244 | 498283 | 42467 | 62948028 |
Dyslipidaemia | 13.76 | 10.23 | 23 | 498504 | 7370 | 62983125 |
Coagulation factor decreased | 13.74 | 10.23 | 9 | 498518 | 91 | 62990404 |
Snoring | 13.66 | 10.23 | 8 | 498519 | 4194 | 62986301 |
Eosinophil percentage increased | 13.66 | 10.23 | 27 | 498500 | 1002 | 62989493 |
Personality change | 13.63 | 10.23 | 21 | 498506 | 6952 | 62983543 |
Psoriatic arthropathy | 13.50 | 10.23 | 584 | 497943 | 90936 | 62899559 |
Device related infection | 13.47 | 10.23 | 118 | 498409 | 23274 | 62967221 |
Accidental death | 13.40 | 10.23 | 40 | 498487 | 1936 | 62988559 |
Osteomyelitis | 13.38 | 10.23 | 135 | 498392 | 25885 | 62964610 |
Limb discomfort | 13.35 | 10.23 | 159 | 498368 | 29557 | 62960938 |
Seasonal allergy | 13.32 | 10.23 | 235 | 498292 | 20715 | 62969780 |
Device deployment issue | 13.31 | 10.23 | 7 | 498520 | 3895 | 62986600 |
Eczema | 13.30 | 10.23 | 176 | 498351 | 32115 | 62958380 |
Skin cancer | 13.26 | 10.23 | 46 | 498481 | 11449 | 62979046 |
Anticholinergic syndrome | 13.21 | 10.23 | 45 | 498482 | 2337 | 62988158 |
Immune reconstitution inflammatory syndrome | 13.21 | 10.23 | 17 | 498510 | 6067 | 62984428 |
Coronary arterial stent insertion | 13.21 | 10.23 | 3 | 498524 | 2826 | 62987669 |
Potentiating drug interaction | 13.19 | 10.23 | 9 | 498518 | 4347 | 62986148 |
Cells in urine | 13.18 | 10.23 | 12 | 498515 | 204 | 62990291 |
Hypersensitivity vasculitis | 13.13 | 10.23 | 8 | 498519 | 4104 | 62986391 |
Allergy to chemicals | 13.13 | 10.23 | 53 | 498474 | 2989 | 62987506 |
Bundle branch block left | 13.10 | 10.23 | 22 | 498505 | 7037 | 62983458 |
Pelvic pain | 13.10 | 10.23 | 58 | 498469 | 13461 | 62977034 |
Sleep disorder | 13.06 | 10.23 | 774 | 497753 | 80792 | 62909703 |
Hallucination | 13.03 | 10.23 | 329 | 498198 | 54488 | 62936007 |
Concomitant disease aggravated | 13.01 | 10.23 | 33 | 498494 | 9079 | 62981416 |
Foot operation | 13.00 | 10.23 | 23 | 498504 | 7208 | 62983287 |
Respiratory symptom | 12.99 | 10.23 | 5 | 498522 | 3342 | 62987153 |
Intestinal haemorrhage | 12.97 | 10.23 | 7 | 498520 | 3840 | 62986655 |
Asthma | 12.97 | 10.23 | 845 | 497682 | 126716 | 62863779 |
COVID-19 immunisation | 12.91 | 10.23 | 37 | 498490 | 1750 | 62988745 |
Thyroid cancer | 12.90 | 10.23 | 15 | 498512 | 5596 | 62984899 |
Muscle disorder | 12.87 | 10.23 | 12 | 498515 | 4957 | 62985538 |
Small fibre neuropathy | 12.86 | 10.23 | 17 | 498510 | 446 | 62990049 |
Blood creatinine decreased | 12.82 | 10.23 | 81 | 498446 | 5464 | 62985031 |
Product monitoring error | 12.80 | 10.23 | 10 | 498517 | 4506 | 62985989 |
Supraventricular tachycardia | 12.78 | 10.23 | 63 | 498464 | 14208 | 62976287 |
Uterine cancer | 12.77 | 10.23 | 11 | 498516 | 4722 | 62985773 |
Haemorrhage intracranial | 12.74 | 10.23 | 58 | 498469 | 13361 | 62977134 |
Ductus arteriosus stenosis foetal | 12.72 | 10.23 | 11 | 498516 | 174 | 62990321 |
Pericardial effusion | 12.69 | 10.23 | 163 | 498364 | 29895 | 62960600 |
Uterine leiomyoma | 12.61 | 10.23 | 34 | 498493 | 9164 | 62981331 |
Patent ductus arteriosus | 12.58 | 10.23 | 9 | 498518 | 4241 | 62986254 |
Body height decreased | 12.54 | 10.23 | 39 | 498488 | 10039 | 62980456 |
Myelocyte count increased | 12.53 | 10.23 | 15 | 498512 | 355 | 62990140 |
Product use in unapproved indication | 12.52 | 10.23 | 1223 | 497304 | 177857 | 62812638 |
Mean cell haemoglobin concentration increased | 12.50 | 10.23 | 18 | 498509 | 513 | 62989982 |
Fixed eruption | 12.49 | 10.23 | 28 | 498499 | 1136 | 62989359 |
Shoulder arthroplasty | 12.48 | 10.23 | 8 | 498519 | 3994 | 62986501 |
Prescribed overdose | 12.47 | 10.23 | 354 | 498173 | 33799 | 62956696 |
Oesophageal stenosis | 12.47 | 10.23 | 5 | 498522 | 3261 | 62987234 |
Renal papillary necrosis | 12.46 | 10.23 | 13 | 498514 | 263 | 62990232 |
Blood triglycerides increased | 12.45 | 10.23 | 53 | 498474 | 12435 | 62978060 |
Tongue disorder | 12.43 | 10.23 | 42 | 498485 | 10538 | 62979957 |
Visual impairment | 12.43 | 10.23 | 539 | 497988 | 83907 | 62906588 |
Exposure to SARS-CoV-2 | 12.40 | 10.23 | 36 | 498491 | 1715 | 62988780 |
Diffuse large B-cell lymphoma | 12.38 | 10.23 | 21 | 498506 | 6691 | 62983804 |
Mental impairment | 12.37 | 10.23 | 63 | 498464 | 14088 | 62976407 |
Oral pain | 12.35 | 10.23 | 153 | 498374 | 28241 | 62962254 |
Lupus vulgaris | 12.31 | 10.23 | 85 | 498442 | 5909 | 62984586 |
Glutathione decreased | 12.31 | 10.23 | 6 | 498521 | 32 | 62990463 |
Agranulocytosis | 12.27 | 10.23 | 132 | 498395 | 25002 | 62965493 |
Arrhythmia | 12.26 | 10.23 | 218 | 498309 | 37922 | 62952573 |
Cardiac failure chronic | 12.25 | 10.23 | 10 | 498517 | 4408 | 62986087 |
Administration site pruritus | 12.24 | 10.23 | 14 | 498513 | 315 | 62990180 |
Suspected COVID-19 | 12.16 | 10.23 | 46 | 498481 | 2516 | 62987979 |
Multiple organ dysfunction syndrome | 12.08 | 10.23 | 346 | 498181 | 56406 | 62934089 |
Large intestine polyp | 12.07 | 10.23 | 29 | 498498 | 8128 | 62982367 |
Skin infection | 12.07 | 10.23 | 175 | 498352 | 14827 | 62975668 |
Chest pain | 12.05 | 10.23 | 1498 | 497029 | 214461 | 62776034 |
Pancreatitis | 12.04 | 10.23 | 293 | 498234 | 48762 | 62941733 |
Injection site haematoma | 12.04 | 10.23 | 22 | 498505 | 6810 | 62983685 |
Haematochezia | 12.03 | 10.23 | 324 | 498203 | 53220 | 62937275 |
Opiates positive | 12.02 | 10.23 | 15 | 498512 | 371 | 62990124 |
Lymphoproliferative disorder | 11.99 | 10.23 | 5 | 498522 | 3185 | 62987310 |
Vitamin K deficiency | 11.98 | 10.23 | 16 | 498511 | 424 | 62990071 |
Central nervous system lesion | 11.97 | 10.23 | 43 | 498484 | 10592 | 62979903 |
Focal dyscognitive seizures | 11.95 | 10.23 | 4 | 498523 | 2917 | 62987578 |
Dissociation | 11.94 | 10.23 | 4 | 498523 | 2915 | 62987580 |
Inflammation | 11.93 | 10.23 | 774 | 497753 | 81499 | 62908996 |
Injury associated with device | 11.89 | 10.23 | 7 | 498520 | 3659 | 62986836 |
Pneumonia aspiration | 11.89 | 10.23 | 195 | 498332 | 34345 | 62956150 |
Nail bed inflammation | 11.83 | 10.23 | 15 | 498512 | 377 | 62990118 |
Blood loss anaemia | 11.80 | 10.23 | 34 | 498493 | 8967 | 62981528 |
Product physical issue | 11.79 | 10.23 | 13 | 498514 | 4967 | 62985528 |
Bronchopulmonary aspergillosis | 11.78 | 10.23 | 32 | 498495 | 8603 | 62981892 |
Band neutrophil percentage increased | 11.77 | 10.23 | 12 | 498515 | 236 | 62990259 |
Spinal pain | 11.77 | 10.23 | 58 | 498469 | 13081 | 62977414 |
Anxiety | 11.76 | 10.23 | 1512 | 497015 | 216029 | 62774466 |
Gastritis | 11.74 | 10.23 | 214 | 498313 | 37089 | 62953406 |
Aortic valve incompetence | 11.74 | 10.23 | 18 | 498509 | 5970 | 62984525 |
Drug tolerance | 11.70 | 10.23 | 23 | 498504 | 6926 | 62983569 |
Lymphadenopathy | 11.68 | 10.23 | 222 | 498305 | 38236 | 62952259 |
Smear cervix abnormal | 11.67 | 10.23 | 50 | 498477 | 2896 | 62987599 |
Obstructive airways disorder | 11.66 | 10.23 | 105 | 498422 | 20594 | 62969901 |
Bradypnoea | 11.65 | 10.23 | 57 | 498470 | 3493 | 62987002 |
Osteolysis | 11.65 | 10.23 | 4 | 498523 | 2870 | 62987625 |
Fungal rhinitis | 11.60 | 10.23 | 6 | 498521 | 37 | 62990458 |
Alpha 1 microglobulin increased | 11.55 | 10.23 | 7 | 498520 | 61 | 62990434 |
Somnambulism | 11.51 | 10.23 | 16 | 498511 | 5527 | 62984968 |
Injection site nodule | 11.51 | 10.23 | 8 | 498519 | 3827 | 62986668 |
Inhibitory drug interaction | 11.49 | 10.23 | 4 | 498523 | 2845 | 62987650 |
Cystitis | 11.46 | 10.23 | 535 | 497992 | 54456 | 62936039 |
Chronic graft versus host disease | 11.44 | 10.23 | 5 | 498522 | 3097 | 62987398 |
Blood bilirubin increased | 11.44 | 10.23 | 377 | 498150 | 36763 | 62953732 |
Urine analysis abnormal | 11.43 | 10.23 | 73 | 498454 | 4943 | 62985552 |
Nerve injury | 11.34 | 10.23 | 40 | 498487 | 9906 | 62980589 |
Left ventricular dysfunction | 11.27 | 10.23 | 52 | 498475 | 11936 | 62978559 |
Tooth extraction | 11.22 | 10.23 | 42 | 498485 | 10222 | 62980273 |
Eye haemorrhage | 11.20 | 10.23 | 32 | 498495 | 8464 | 62982031 |
Pneumonia viral | 11.15 | 10.23 | 103 | 498424 | 7819 | 62982676 |
Hip arthroplasty | 11.13 | 10.23 | 469 | 498058 | 47177 | 62943318 |
Encephalopathy | 11.13 | 10.23 | 389 | 498138 | 38231 | 62952264 |
Cystic fibrosis | 11.11 | 10.23 | 6 | 498521 | 3290 | 62987205 |
Acute graft versus host disease | 11.11 | 10.23 | 11 | 498516 | 4417 | 62986078 |
Nervous system disorder | 11.10 | 10.23 | 94 | 498433 | 18672 | 62971823 |
Haemolysis | 11.09 | 10.23 | 91 | 498436 | 6677 | 62983818 |
Necrotic lymphadenopathy | 11.09 | 10.23 | 7 | 498520 | 66 | 62990429 |
Infective pulmonary exacerbation of cystic fibrosis | 11.06 | 10.23 | 34 | 498493 | 8783 | 62981712 |
Blood immunoglobulin A increased | 11.04 | 10.23 | 21 | 498506 | 757 | 62989738 |
Erysipelas | 11.00 | 10.23 | 29 | 498498 | 7876 | 62982619 |
Application site rash | 10.98 | 10.23 | 3 | 498524 | 2495 | 62988000 |
Laryngospasm | 10.98 | 10.23 | 5 | 498522 | 3023 | 62987472 |
Hypoacusis | 10.94 | 10.23 | 129 | 498398 | 24022 | 62966473 |
Blood prolactin increased | 10.93 | 10.23 | 7 | 498520 | 3496 | 62986999 |
Lung neoplasm malignant | 10.88 | 10.23 | 100 | 498427 | 19533 | 62970962 |
Glucose tolerance impaired | 10.87 | 10.23 | 22 | 498505 | 6555 | 62983940 |
Diffuse axonal injury | 10.87 | 10.23 | 8 | 498519 | 99 | 62990396 |
Aggression | 10.84 | 10.23 | 125 | 498402 | 23373 | 62967122 |
Staphylococcal infection | 10.80 | 10.23 | 244 | 498283 | 41012 | 62949483 |
Breast cancer metastatic | 10.79 | 10.23 | 53 | 498474 | 11965 | 62978530 |
Infusion site discolouration | 10.79 | 10.23 | 22 | 498505 | 835 | 62989660 |
Paradoxical drug reaction | 10.79 | 10.23 | 10 | 498517 | 4142 | 62986353 |
Abnormal loss of weight | 10.75 | 10.23 | 18 | 498509 | 5764 | 62984731 |
Taste disorder | 10.75 | 10.23 | 63 | 498464 | 13599 | 62976896 |
Necrosis ischaemic | 10.74 | 10.23 | 22 | 498505 | 838 | 62989657 |
Pallor | 10.71 | 10.23 | 172 | 498355 | 30396 | 62960099 |
Transfusion-related acute lung injury | 10.69 | 10.23 | 9 | 498518 | 137 | 62990358 |
Hypoaesthesia | 10.68 | 10.23 | 1158 | 497369 | 167235 | 62823260 |
Orbital compartment syndrome | 10.67 | 10.23 | 7 | 498520 | 71 | 62990424 |
Injection site vesicles | 10.67 | 10.23 | 5 | 498522 | 2972 | 62987523 |
Granuloma | 10.65 | 10.23 | 18 | 498509 | 5743 | 62984752 |
Catheter site bruise | 10.63 | 10.23 | 16 | 498511 | 475 | 62990020 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 10.62 | 10.23 | 38 | 498489 | 2023 | 62988472 |
Femoral neck fracture | 10.59 | 10.23 | 33 | 498494 | 8490 | 62982005 |
Erythema | 10.57 | 10.23 | 1213 | 497314 | 174538 | 62815957 |
Jaw disorder | 10.56 | 10.23 | 16 | 498511 | 5333 | 62985162 |
Gout | 10.54 | 10.23 | 61 | 498466 | 13210 | 62977285 |
Human herpesvirus 6 infection | 10.54 | 10.23 | 5 | 498522 | 2952 | 62987543 |
Anosognosia | 10.51 | 10.23 | 6 | 498521 | 3190 | 62987305 |
Hyperhidrosis | 10.51 | 10.23 | 717 | 497810 | 107119 | 62883376 |
Stress fracture | 10.50 | 10.23 | 30 | 498497 | 7933 | 62982562 |
Cellulitis | 10.48 | 10.23 | 531 | 497996 | 81427 | 62909068 |
Bipolar disorder | 10.48 | 10.23 | 30 | 498497 | 7930 | 62982565 |
Epilepsy with myoclonic-atonic seizures | 10.48 | 10.23 | 8 | 498519 | 105 | 62990390 |
Eating disorder | 10.48 | 10.23 | 97 | 498430 | 18919 | 62971576 |
Tumour marker increased | 10.40 | 10.23 | 14 | 498513 | 4901 | 62985594 |
Autonomic dysreflexia | 10.37 | 10.23 | 13 | 498514 | 323 | 62990172 |
Base excess | 10.35 | 10.23 | 7 | 498520 | 75 | 62990420 |
Abdominal pain upper | 10.32 | 10.23 | 1807 | 496720 | 204637 | 62785858 |
Haemarthrosis | 10.30 | 10.23 | 6 | 498521 | 3155 | 62987340 |
Left ventricular failure | 10.30 | 10.23 | 18 | 498509 | 5669 | 62984826 |
Hysterectomy | 10.30 | 10.23 | 39 | 498488 | 9460 | 62981035 |
Subdural haematoma | 10.27 | 10.23 | 68 | 498459 | 14260 | 62976235 |
Blood immunoglobulin G increased | 10.25 | 10.23 | 42 | 498485 | 2385 | 62988110 |
Malignant melanoma | 10.25 | 10.23 | 50 | 498477 | 11306 | 62979189 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Toxicity to various agents | 1333.18 | 10.35 | 3240 | 192174 | 197122 | 34564395 |
Completed suicide | 1204.96 | 10.35 | 2049 | 193365 | 96119 | 34665398 |
Exposure to toxic agent | 503.76 | 10.35 | 292 | 195122 | 3383 | 34758134 |
Infusion related reaction | 474.76 | 10.35 | 968 | 194446 | 52089 | 34709428 |
Blood pressure fluctuation | 433.37 | 10.35 | 616 | 194798 | 24633 | 34736884 |
Overdose | 386.14 | 10.35 | 1253 | 194161 | 89806 | 34671711 |
Intentional product misuse | 346.71 | 10.35 | 779 | 194635 | 44832 | 34716685 |
Intentional overdose | 301.24 | 10.35 | 718 | 194696 | 42956 | 34718561 |
Acute hepatic failure | 283.27 | 10.35 | 371 | 195043 | 13703 | 34747814 |
Drug ineffective | 274.71 | 10.35 | 1470 | 193944 | 455281 | 34306236 |
Drug abuse | 255.96 | 10.35 | 1165 | 194249 | 97931 | 34663586 |
Heart rate decreased | 220.05 | 10.35 | 523 | 194891 | 31222 | 34730295 |
Blood pressure increased | 168.48 | 10.35 | 952 | 194462 | 87150 | 34674367 |
Hepatic cytolysis | 166.03 | 10.35 | 294 | 195120 | 14202 | 34747315 |
Cytokine release syndrome | 137.52 | 10.35 | 357 | 195057 | 22520 | 34738997 |
Metabolic acidosis | 132.19 | 10.35 | 539 | 194875 | 43141 | 34718376 |
Oxygen saturation decreased | 120.86 | 10.35 | 608 | 194806 | 53210 | 34708307 |
Myocardial infarction | 110.12 | 10.35 | 330 | 195084 | 120755 | 34640762 |
Respiratory arrest | 108.08 | 10.35 | 374 | 195040 | 27669 | 34733848 |
COVID-19 | 106.14 | 10.35 | 770 | 194644 | 76780 | 34684737 |
Anion gap | 106.01 | 10.35 | 64 | 195350 | 803 | 34760714 |
Coagulopathy | 104.08 | 10.35 | 294 | 195120 | 19495 | 34742022 |
Blood pressure systolic increased | 102.69 | 10.35 | 322 | 195092 | 22630 | 34738887 |
Analgesic drug level increased | 101.61 | 10.35 | 62 | 195352 | 794 | 34760723 |
Blood pressure diastolic abnormal | 100.03 | 10.35 | 129 | 195285 | 4689 | 34756828 |
Hepatotoxicity | 98.51 | 10.35 | 304 | 195110 | 21181 | 34740336 |
Intentional product use issue | 98.02 | 10.35 | 621 | 194793 | 59195 | 34702322 |
Methaemoglobinaemia | 97.46 | 10.35 | 110 | 195304 | 3471 | 34758046 |
Drug resistance | 95.96 | 10.35 | 15 | 195399 | 25912 | 34735605 |
Poisoning | 91.89 | 10.35 | 208 | 195206 | 12018 | 34749499 |
Sinusitis | 91.02 | 10.35 | 465 | 194949 | 40937 | 34720580 |
Treatment failure | 90.12 | 10.35 | 77 | 195337 | 46620 | 34714897 |
Product dose omission issue | 82.57 | 10.35 | 366 | 195048 | 119345 | 34642172 |
Suicide attempt | 82.29 | 10.35 | 434 | 194980 | 38682 | 34722835 |
Accidental overdose | 81.46 | 10.35 | 273 | 195141 | 19867 | 34741650 |
Cardio-respiratory arrest | 75.70 | 10.35 | 549 | 194865 | 54724 | 34706793 |
Diarrhoea | 75.03 | 10.35 | 1636 | 193778 | 388276 | 34373241 |
Pyroglutamic acidosis | 72.42 | 10.35 | 39 | 195375 | 387 | 34761130 |
Cardiac failure congestive | 72.08 | 10.35 | 232 | 195182 | 83038 | 34678479 |
Body temperature decreased | 71.85 | 10.35 | 197 | 195217 | 12837 | 34748680 |
Medication error | 70.72 | 10.35 | 307 | 195107 | 25258 | 34736259 |
Infusion site extravasation | 70.13 | 10.35 | 103 | 195311 | 4241 | 34757276 |
Blood pressure systolic abnormal | 68.69 | 10.35 | 97 | 195317 | 3851 | 34757666 |
Blood pressure diastolic increased | 68.26 | 10.35 | 110 | 195304 | 4915 | 34756602 |
Febrile neutropenia | 66.63 | 10.35 | 1105 | 194309 | 135744 | 34625773 |
Respiratory depression | 65.52 | 10.35 | 220 | 195194 | 16025 | 34745492 |
Heart rate irregular | 64.58 | 10.35 | 215 | 195199 | 15592 | 34745925 |
Cardiac failure | 58.74 | 10.35 | 286 | 195128 | 90962 | 34670555 |
Hypotension | 56.45 | 10.35 | 1630 | 193784 | 220019 | 34541498 |
Suspected suicide | 55.27 | 10.35 | 97 | 195317 | 4651 | 34756866 |
Poisoning deliberate | 54.07 | 10.35 | 129 | 195285 | 7715 | 34753802 |
Blood pressure diastolic decreased | 53.70 | 10.35 | 141 | 195273 | 8953 | 34752564 |
Substance abuse | 53.03 | 10.35 | 126 | 195288 | 7515 | 34754002 |
Therapeutic product effect incomplete | 51.68 | 10.35 | 130 | 195284 | 50411 | 34711106 |
Infusion site pain | 50.55 | 10.35 | 83 | 195331 | 3768 | 34757749 |
Depressed level of consciousness | 50.54 | 10.35 | 411 | 195003 | 42430 | 34719087 |
Alanine aminotransferase increased | 50.38 | 10.35 | 681 | 194733 | 80134 | 34681383 |
Exposure via ingestion | 49.41 | 10.35 | 61 | 195353 | 2120 | 34759397 |
Hepatic necrosis | 48.76 | 10.35 | 81 | 195333 | 3713 | 34757804 |
Chills | 48.11 | 10.35 | 677 | 194737 | 80366 | 34681151 |
Coronary artery disease | 48.04 | 10.35 | 126 | 195288 | 48179 | 34713338 |
Wrong technique in product usage process | 47.44 | 10.35 | 80 | 195334 | 35906 | 34725611 |
Appendicolith | 45.43 | 10.35 | 128 | 195286 | 8473 | 34753044 |
Infusion site swelling | 45.38 | 10.35 | 63 | 195351 | 2461 | 34759056 |
Anaemia | 45.02 | 10.35 | 978 | 194436 | 232357 | 34529160 |
Renal cortical necrosis | 44.81 | 10.35 | 23 | 195391 | 205 | 34761312 |
Liver injury | 44.51 | 10.35 | 183 | 195231 | 14695 | 34746822 |
Dizziness | 43.58 | 10.35 | 911 | 194503 | 217610 | 34543907 |
Inappropriate schedule of product administration | 43.04 | 10.35 | 535 | 194879 | 61761 | 34699756 |
Toxic epidermal necrolysis | 42.69 | 10.35 | 236 | 195178 | 21410 | 34740107 |
Body temperature increased | 42.38 | 10.35 | 201 | 195213 | 17167 | 34744350 |
Myelosuppression | 41.99 | 10.35 | 28 | 195386 | 19237 | 34742280 |
Disease progression | 39.73 | 10.35 | 399 | 195015 | 107678 | 34653839 |
Prostate cancer | 38.23 | 10.35 | 105 | 195309 | 39544 | 34721973 |
Ear infection | 38.15 | 10.35 | 135 | 195279 | 10096 | 34751421 |
Tachycardia | 38.12 | 10.35 | 676 | 194738 | 84096 | 34677421 |
Poor venous access | 37.64 | 10.35 | 87 | 195327 | 5096 | 34756421 |
Renal impairment | 37.25 | 10.35 | 343 | 195071 | 94170 | 34667347 |
Product prescribing error | 37.14 | 10.35 | 44 | 195370 | 22883 | 34738634 |
Heart rate increased | 36.89 | 10.35 | 409 | 195005 | 45934 | 34715583 |
Anion gap abnormal | 36.31 | 10.35 | 19 | 195395 | 177 | 34761340 |
Bone marrow failure | 35.88 | 10.35 | 68 | 195346 | 29185 | 34732332 |
Injection site pain | 35.62 | 10.35 | 106 | 195308 | 38899 | 34722618 |
Body temperature fluctuation | 35.18 | 10.35 | 45 | 195369 | 1622 | 34759895 |
Serotonin syndrome | 35.17 | 10.35 | 211 | 195203 | 19722 | 34741795 |
Aspartate aminotransferase increased | 34.67 | 10.35 | 552 | 194862 | 67231 | 34694286 |
Asthenia | 34.52 | 10.35 | 1076 | 194338 | 244175 | 34517342 |
Abdominal pain | 34.39 | 10.35 | 1176 | 194238 | 162442 | 34599075 |
Infusion site erythema | 33.99 | 10.35 | 52 | 195362 | 2221 | 34759296 |
Mydriasis | 33.72 | 10.35 | 103 | 195311 | 7134 | 34754383 |
Bladder cancer | 33.71 | 10.35 | 25 | 195389 | 16253 | 34745264 |
Therapeutic response decreased | 33.51 | 10.35 | 71 | 195343 | 29242 | 34732275 |
Therapeutic response shortened | 33.22 | 10.35 | 104 | 195310 | 7300 | 34754217 |
Neuropathy peripheral | 32.88 | 10.35 | 302 | 195112 | 82961 | 34678556 |
Drug interaction | 32.84 | 10.35 | 987 | 194427 | 224959 | 34536558 |
Infusion site pruritus | 32.74 | 10.35 | 31 | 195383 | 792 | 34760725 |
Foetal exposure during pregnancy | 32.36 | 10.35 | 107 | 195307 | 37994 | 34723523 |
Pharyngeal paraesthesia | 31.54 | 10.35 | 28 | 195386 | 657 | 34760860 |
Depression | 31.46 | 10.35 | 369 | 195045 | 96729 | 34664788 |
Coma | 31.42 | 10.35 | 392 | 195022 | 45286 | 34716231 |
Appendicitis | 30.25 | 10.35 | 163 | 195251 | 14644 | 34746873 |
Memory impairment | 30.09 | 10.35 | 132 | 195282 | 43186 | 34718331 |
Cerebral haemorrhage | 29.75 | 10.35 | 98 | 195316 | 34839 | 34726678 |
Stevens-Johnson syndrome | 28.96 | 10.35 | 191 | 195223 | 18448 | 34743069 |
Balance disorder | 28.78 | 10.35 | 123 | 195291 | 40531 | 34720986 |
Hypoxia | 28.30 | 10.35 | 449 | 194965 | 54646 | 34706871 |
Hepatitis fulminant | 27.90 | 10.35 | 68 | 195346 | 4122 | 34757395 |
Hospitalisation | 27.71 | 10.35 | 195 | 195219 | 56707 | 34704810 |
Cerebrovascular accident | 27.59 | 10.35 | 322 | 195092 | 84489 | 34677028 |
Infusion site bruising | 27.54 | 10.35 | 27 | 195387 | 721 | 34760796 |
Respiratory rate increased | 27.50 | 10.35 | 119 | 195295 | 9775 | 34751742 |
Sopor | 27.32 | 10.35 | 17 | 195397 | 12119 | 34749398 |
Full blood count abnormal | 26.98 | 10.35 | 39 | 195375 | 18629 | 34742888 |
Head discomfort | 26.56 | 10.35 | 66 | 195348 | 4050 | 34757467 |
Psoriasis | 26.52 | 10.35 | 119 | 195295 | 38693 | 34722824 |
Feeling abnormal | 26.44 | 10.35 | 226 | 195188 | 63009 | 34698508 |
Myocardial fibrosis | 26.35 | 10.35 | 33 | 195381 | 1164 | 34760353 |
Nasopharyngitis | 26.33 | 10.35 | 543 | 194871 | 69425 | 34692092 |
Diabetes mellitus | 26.21 | 10.35 | 154 | 195260 | 46719 | 34714798 |
Acute myocardial infarction | 26.20 | 10.35 | 184 | 195230 | 53535 | 34707982 |
Hepatic failure | 25.78 | 10.35 | 301 | 195113 | 34230 | 34727287 |
Cardiac arrest | 25.74 | 10.35 | 712 | 194702 | 95447 | 34666070 |
Therapy non-responder | 25.57 | 10.35 | 122 | 195292 | 39024 | 34722493 |
Glycosylated haemoglobin increased | 25.45 | 10.35 | 16 | 195398 | 11344 | 34750173 |
Throat irritation | 24.74 | 10.35 | 121 | 195293 | 10464 | 34751053 |
Neutrophil percentage increased | 24.73 | 10.35 | 40 | 195374 | 1793 | 34759724 |
Therapeutic product effect decreased | 24.66 | 10.35 | 105 | 195309 | 34638 | 34726879 |
Progressive multifocal leukoencephalopathy | 24.41 | 10.35 | 12 | 195402 | 9752 | 34751765 |
Pyrexia | 24.33 | 10.35 | 2169 | 193245 | 330844 | 34430673 |
Fatigue | 24.20 | 10.35 | 1765 | 193649 | 368888 | 34392629 |
Oesophageal carcinoma | 23.93 | 10.35 | 11 | 195403 | 9293 | 34752224 |
Haematotoxicity | 23.85 | 10.35 | 8 | 195406 | 8186 | 34753331 |
Ductus arteriosus premature closure | 23.78 | 10.35 | 16 | 195398 | 245 | 34761272 |
Generalised bullous fixed drug eruption | 23.55 | 10.35 | 11 | 195403 | 78 | 34761439 |
Urine sodium decreased | 23.51 | 10.35 | 14 | 195400 | 171 | 34761346 |
Dyspnoea exertional | 23.25 | 10.35 | 144 | 195270 | 43135 | 34718382 |
Immune reconstitution inflammatory syndrome | 23.08 | 10.35 | 10 | 195404 | 8749 | 34752768 |
Fixed eruption | 22.80 | 10.35 | 37 | 195377 | 1663 | 34759854 |
Agitation | 22.77 | 10.35 | 449 | 194965 | 56950 | 34704567 |
Pemphigus | 22.56 | 10.35 | 36 | 195378 | 1595 | 34759922 |
Blood pH decreased | 22.54 | 10.35 | 44 | 195370 | 2290 | 34759227 |
Asthma | 22.36 | 10.35 | 143 | 195271 | 42513 | 34719004 |
Vital functions abnormal | 22.25 | 10.35 | 16 | 195398 | 274 | 34761243 |
International normalised ratio increased | 22.19 | 10.35 | 380 | 195034 | 46947 | 34714570 |
Graft versus host disease | 22.19 | 10.35 | 16 | 195398 | 10553 | 34750964 |
Blood phosphorus increased | 21.56 | 10.35 | 93 | 195321 | 7628 | 34753889 |
Post transplant lymphoproliferative disorder | 21.56 | 10.35 | 5 | 195409 | 6523 | 34754994 |
Haemolysis | 21.47 | 10.35 | 96 | 195318 | 7998 | 34753519 |
Cerebral infarction | 21.37 | 10.35 | 80 | 195334 | 27375 | 34734142 |
C-reactive protein abnormal | 21.33 | 10.35 | 11 | 195403 | 8699 | 34752818 |
Dyspnoea | 21.21 | 10.35 | 1816 | 193598 | 374966 | 34386551 |
Infusion site rash | 21.00 | 10.35 | 20 | 195394 | 515 | 34761002 |
Therapy partial responder | 20.92 | 10.35 | 14 | 195400 | 9602 | 34751915 |
Malignant neoplasm progression | 20.92 | 10.35 | 356 | 195058 | 87690 | 34673827 |
Pathogen resistance | 20.37 | 10.35 | 14 | 195400 | 9468 | 34752049 |
Chronic gastrointestinal bleeding | 20.24 | 10.35 | 16 | 195398 | 318 | 34761199 |
SARS-CoV-2 test positive | 20.19 | 10.35 | 76 | 195338 | 5857 | 34755660 |
Decreased appetite | 20.10 | 10.35 | 744 | 194670 | 165648 | 34595869 |
Flushing | 20.10 | 10.35 | 273 | 195141 | 32147 | 34729370 |
Oedema peripheral | 20.04 | 10.35 | 513 | 194901 | 119299 | 34642218 |
Gait inability | 19.99 | 10.35 | 55 | 195359 | 20703 | 34740814 |
Throat tightness | 19.86 | 10.35 | 96 | 195318 | 8262 | 34753255 |
Hyperaesthesia | 19.83 | 10.35 | 64 | 195350 | 4566 | 34756951 |
Osteonecrosis | 19.71 | 10.35 | 33 | 195381 | 14857 | 34746660 |
Erectile dysfunction | 19.63 | 10.35 | 55 | 195359 | 20582 | 34740935 |
Infusion site haemorrhage | 19.47 | 10.35 | 26 | 195388 | 978 | 34760539 |
Acidosis | 19.40 | 10.35 | 116 | 195298 | 10829 | 34750688 |
Acute lung injury | 19.09 | 10.35 | 32 | 195382 | 1478 | 34760039 |
Osteonecrosis of jaw | 19.08 | 10.35 | 45 | 195369 | 17844 | 34743673 |
Prostatic specific antigen increased | 19.01 | 10.35 | 33 | 195381 | 14647 | 34746870 |
Labelled drug-drug interaction medication error | 18.96 | 10.35 | 34 | 195380 | 14905 | 34746612 |
Cytopenia | 18.96 | 10.35 | 26 | 195388 | 12697 | 34748820 |
Enterocolitis infectious | 18.92 | 10.35 | 34 | 195380 | 1661 | 34759856 |
Pancytopenia | 18.83 | 10.35 | 397 | 195017 | 94760 | 34666757 |
Lymphocyte count abnormal | 18.75 | 10.35 | 28 | 195386 | 1170 | 34760347 |
Inadequate analgesia | 18.46 | 10.35 | 47 | 195367 | 2928 | 34758589 |
Immune effector cell-associated neurotoxicity syndrome | 18.39 | 10.35 | 54 | 195360 | 3659 | 34757858 |
Syncope | 18.25 | 10.35 | 381 | 195033 | 91070 | 34670447 |
Somnolence | 18.16 | 10.35 | 777 | 194637 | 110339 | 34651178 |
Delusion of grandeur | 18.00 | 10.35 | 27 | 195387 | 1133 | 34760384 |
Lymphocyte percentage decreased | 17.98 | 10.35 | 38 | 195376 | 2094 | 34759423 |
Diabetic ketoacidosis | 17.95 | 10.35 | 47 | 195367 | 17985 | 34743532 |
Cytomegalovirus infection | 17.93 | 10.35 | 80 | 195334 | 26055 | 34735462 |
Dry skin | 17.91 | 10.35 | 102 | 195312 | 31185 | 34730332 |
Insomnia | 17.88 | 10.35 | 443 | 194971 | 103464 | 34658053 |
Product substitution issue | 17.87 | 10.35 | 18 | 195396 | 10077 | 34751440 |
Myopathy | 17.84 | 10.35 | 23 | 195391 | 11531 | 34749986 |
Aminoaciduria | 17.81 | 10.35 | 14 | 195400 | 276 | 34761241 |
Visual impairment | 17.77 | 10.35 | 122 | 195292 | 35680 | 34725837 |
Visual acuity reduced | 17.72 | 10.35 | 40 | 195374 | 16109 | 34745408 |
Consciousness fluctuating | 17.53 | 10.35 | 27 | 195387 | 1160 | 34760357 |
Incorrect drug administration rate | 17.52 | 10.35 | 33 | 195381 | 1672 | 34759845 |
Hypertriglyceridaemia | 17.46 | 10.35 | 13 | 195401 | 8435 | 34753082 |
Obstructive airways disorder | 17.31 | 10.35 | 38 | 195376 | 15456 | 34746061 |
Psoriatic arthropathy | 17.22 | 10.35 | 55 | 195359 | 19743 | 34741774 |
Granulomatosis with polyangiitis | 17.22 | 10.35 | 27 | 195387 | 1178 | 34760339 |
Cardiac disorder | 17.20 | 10.35 | 156 | 195258 | 42970 | 34718547 |
Contraindicated product administered | 17.11 | 10.35 | 62 | 195352 | 21419 | 34740098 |
Unresponsive to stimuli | 17.03 | 10.35 | 232 | 195182 | 27337 | 34734180 |
Insurance issue | 16.80 | 10.35 | 36 | 195378 | 2003 | 34759514 |
Venoocclusive liver disease | 16.80 | 10.35 | 12 | 195402 | 7954 | 34753563 |
Stress | 16.60 | 10.35 | 250 | 195164 | 30097 | 34731420 |
Angina pectoris | 16.51 | 10.35 | 105 | 195309 | 31258 | 34730259 |
COVID-19 pneumonia | 16.48 | 10.35 | 156 | 195258 | 16811 | 34744706 |
Cerebral artery thrombosis | 16.37 | 10.35 | 21 | 195393 | 759 | 34760758 |
Injection site reaction | 16.24 | 10.35 | 30 | 195384 | 13003 | 34748514 |
Oxygen saturation abnormal | 16.20 | 10.35 | 30 | 195384 | 1500 | 34760017 |
Hypoaesthesia | 16.07 | 10.35 | 244 | 195170 | 61200 | 34700317 |
Drug ineffective for unapproved indication | 16.02 | 10.35 | 73 | 195341 | 23642 | 34737875 |
Gynaecomastia | 16.00 | 10.35 | 20 | 195394 | 10160 | 34751357 |
Brain scan abnormal | 15.87 | 10.35 | 22 | 195392 | 858 | 34760659 |
Accidental exposure to product by child | 15.70 | 10.35 | 29 | 195385 | 1447 | 34760070 |
Sulphaemoglobinaemia | 15.63 | 10.35 | 6 | 195408 | 24 | 34761493 |
Blood glucose increased | 15.44 | 10.35 | 271 | 195143 | 66447 | 34695070 |
Incorrect dose administered | 15.42 | 10.35 | 315 | 195099 | 40200 | 34721317 |
Mixed liver injury | 15.41 | 10.35 | 43 | 195371 | 2830 | 34758687 |
Ductus arteriosus stenosis foetal | 15.37 | 10.35 | 11 | 195403 | 187 | 34761330 |
Aplastic anaemia | 15.36 | 10.35 | 100 | 195314 | 9616 | 34751901 |
Systemic infection | 15.33 | 10.35 | 5 | 195409 | 5207 | 34756310 |
Sudden infant death syndrome | 15.29 | 10.35 | 12 | 195402 | 236 | 34761281 |
Dehydration | 15.27 | 10.35 | 583 | 194831 | 129386 | 34632131 |
Vomiting | 15.26 | 10.35 | 1594 | 193820 | 246027 | 34515490 |
Drug-induced liver injury | 15.19 | 10.35 | 236 | 195178 | 28596 | 34732921 |
Cardiac failure chronic | 15.18 | 10.35 | 13 | 195401 | 7866 | 34753651 |
Device leakage | 15.09 | 10.35 | 9 | 195405 | 6566 | 34754951 |
Upper respiratory tract infection | 14.98 | 10.35 | 264 | 195150 | 32795 | 34728722 |
Bilirubin urine present | 14.87 | 10.35 | 10 | 195404 | 153 | 34761364 |
Acute generalised exanthematous pustulosis | 14.81 | 10.35 | 76 | 195338 | 6700 | 34754817 |
Muscle spasms | 14.80 | 10.35 | 313 | 195101 | 74688 | 34686829 |
Blood triglycerides increased | 14.79 | 10.35 | 36 | 195378 | 14123 | 34747394 |
Deep vein thrombosis | 14.79 | 10.35 | 266 | 195148 | 64982 | 34696535 |
Fall | 14.70 | 10.35 | 957 | 194457 | 201928 | 34559589 |
Gait disturbance | 14.64 | 10.35 | 363 | 195051 | 84777 | 34676740 |
Failure to suspend medication | 14.64 | 10.35 | 15 | 195399 | 423 | 34761094 |
Pulmonary congestion | 14.61 | 10.35 | 129 | 195285 | 13636 | 34747881 |
Infusion site nodule | 14.57 | 10.35 | 9 | 195405 | 118 | 34761399 |
Electrocardiogram QRS complex prolonged | 14.48 | 10.35 | 60 | 195354 | 4834 | 34756683 |
BK virus infection | 14.42 | 10.35 | 7 | 195407 | 5731 | 34755786 |
Renal papillary necrosis | 14.38 | 10.35 | 10 | 195404 | 162 | 34761355 |
Encephalopathy | 14.24 | 10.35 | 277 | 195137 | 35042 | 34726475 |
Brain death | 14.24 | 10.35 | 40 | 195374 | 2643 | 34758874 |
Rhinalgia | 14.23 | 10.35 | 23 | 195391 | 1030 | 34760487 |
Atrial fibrillation | 14.16 | 10.35 | 550 | 194864 | 121843 | 34639674 |
Clostridium test positive | 14.13 | 10.35 | 46 | 195368 | 3296 | 34758221 |
Dependent personality disorder | 14.07 | 10.35 | 8 | 195406 | 89 | 34761428 |
Cardiogenic shock | 14.07 | 10.35 | 218 | 195196 | 26400 | 34735117 |
Urticaria | 14.01 | 10.35 | 452 | 194962 | 61925 | 34699592 |
Injection site swelling | 13.96 | 10.35 | 27 | 195387 | 11500 | 34750017 |
Sexual dysfunction | 13.95 | 10.35 | 9 | 195405 | 6294 | 34755223 |
Bezoar | 13.94 | 10.35 | 24 | 195390 | 1133 | 34760384 |
Parkinsonism | 13.85 | 10.35 | 15 | 195399 | 8123 | 34753394 |
Anal fissure | 13.82 | 10.35 | 54 | 195360 | 4236 | 34757281 |
Peripheral swelling | 13.80 | 10.35 | 324 | 195090 | 76217 | 34685300 |
Urethral valves | 13.79 | 10.35 | 12 | 195402 | 274 | 34761243 |
Hepatitis C | 13.75 | 10.35 | 21 | 195393 | 9809 | 34751708 |
Product quality issue | 13.68 | 10.35 | 49 | 195365 | 16986 | 34744531 |
Suicidal ideation | 13.65 | 10.35 | 152 | 195262 | 40236 | 34721281 |
Injection site haemorrhage | 13.54 | 10.35 | 21 | 195393 | 9747 | 34751770 |
Transaminases increased | 13.54 | 10.35 | 218 | 195196 | 26605 | 34734912 |
Therapy cessation | 13.51 | 10.35 | 49 | 195365 | 16924 | 34744593 |
Rheumatoid arthritis | 13.48 | 10.35 | 294 | 195120 | 37944 | 34723573 |
Tooth infection | 13.47 | 10.35 | 74 | 195340 | 6697 | 34754820 |
Vanishing bile duct syndrome | 13.44 | 10.35 | 22 | 195392 | 996 | 34760521 |
Severe invasive streptococcal infection | 13.28 | 10.35 | 6 | 195408 | 39 | 34761478 |
Immunoglobulin G4 related disease | 13.25 | 10.35 | 9 | 195405 | 140 | 34761377 |
Loss of personal independence in daily activities | 13.24 | 10.35 | 120 | 195294 | 33059 | 34728458 |
Prothrombin time prolonged | 13.19 | 10.35 | 94 | 195320 | 9312 | 34752205 |
Rhinitis | 13.10 | 10.35 | 70 | 195344 | 6268 | 34755249 |
Self-medication | 13.09 | 10.35 | 39 | 195375 | 2664 | 34758853 |
Erythema multiforme | 13.06 | 10.35 | 88 | 195326 | 8561 | 34752956 |
Hypotensive crisis | 12.95 | 10.35 | 7 | 195407 | 70 | 34761447 |
Ejection fraction decreased | 12.92 | 10.35 | 59 | 195355 | 19095 | 34742422 |
Epilepsy | 12.89 | 10.35 | 69 | 195345 | 21426 | 34740091 |
Intraocular pressure increased | 12.89 | 10.35 | 7 | 195407 | 5376 | 34756141 |
Hyperchloraemia | 12.85 | 10.35 | 15 | 195399 | 491 | 34761026 |
Administration site erythema | 12.78 | 10.35 | 7 | 195407 | 72 | 34761445 |
Thrombotic microangiopathy | 12.78 | 10.35 | 25 | 195389 | 10605 | 34750912 |
COVID-19 immunisation | 12.75 | 10.35 | 11 | 195403 | 248 | 34761269 |
Lung neoplasm malignant | 12.70 | 10.35 | 52 | 195362 | 17343 | 34744174 |
Akathisia | 12.67 | 10.35 | 16 | 195398 | 8093 | 34753424 |
Pemphigoid | 12.63 | 10.35 | 18 | 195396 | 8648 | 34752869 |
Hepatocellular carcinoma | 12.61 | 10.35 | 14 | 195400 | 7495 | 34754022 |
Burn of internal organs | 12.58 | 10.35 | 3 | 195411 | 0 | 34761517 |
Drug intolerance | 12.53 | 10.35 | 246 | 195168 | 59324 | 34702193 |
Status epilepticus | 12.46 | 10.35 | 33 | 195381 | 12581 | 34748936 |
Eye infection | 12.46 | 10.35 | 47 | 195367 | 3626 | 34757891 |
Maple syrup disease | 12.42 | 10.35 | 4 | 195410 | 8 | 34761509 |
Trichoglossia | 12.38 | 10.35 | 12 | 195402 | 316 | 34761201 |
Anti-erythrocyte antibody positive | 12.35 | 10.35 | 6 | 195408 | 47 | 34761470 |
Myalgia | 12.28 | 10.35 | 367 | 195047 | 83743 | 34677774 |
Product complaint | 12.25 | 10.35 | 9 | 195405 | 5881 | 34755636 |
Electrocardiogram QT prolonged | 11.98 | 10.35 | 159 | 195255 | 40793 | 34720724 |
Tooth injury | 11.98 | 10.35 | 23 | 195391 | 1182 | 34760335 |
Leukopenia | 11.92 | 10.35 | 264 | 195150 | 62592 | 34698925 |
Wound infection | 11.89 | 10.35 | 74 | 195340 | 7005 | 34754512 |
Second primary malignancy | 11.87 | 10.35 | 16 | 195398 | 7870 | 34753647 |
Infusion site mass | 11.84 | 10.35 | 12 | 195402 | 334 | 34761183 |
Fibrin D dimer increased | 11.76 | 10.35 | 51 | 195363 | 4193 | 34757324 |
Obesity | 11.75 | 10.35 | 35 | 195379 | 12843 | 34748674 |
Multiple organ dysfunction syndrome | 11.75 | 10.35 | 532 | 194882 | 76034 | 34685483 |
Injection site bruising | 11.65 | 10.35 | 19 | 195395 | 8644 | 34752873 |
Environmental exposure | 11.62 | 10.35 | 11 | 195403 | 281 | 34761236 |
Drug level below therapeutic | 11.59 | 10.35 | 62 | 195352 | 5553 | 34755964 |
Alopecia | 11.59 | 10.35 | 84 | 195330 | 24271 | 34737246 |
Migraine | 11.59 | 10.35 | 149 | 195265 | 17329 | 34744188 |
Hypothermia | 11.55 | 10.35 | 101 | 195313 | 10647 | 34750870 |
Pyroglutamate increased | 11.52 | 10.35 | 11 | 195403 | 284 | 34761233 |
Platelet transfusion | 11.51 | 10.35 | 26 | 195388 | 1500 | 34760017 |
Prostate infection | 11.47 | 10.35 | 20 | 195394 | 954 | 34760563 |
Crystal urine present | 11.47 | 10.35 | 14 | 195400 | 481 | 34761036 |
Testicular infarction | 11.46 | 10.35 | 6 | 195408 | 56 | 34761461 |
Acute phase reaction | 11.45 | 10.35 | 7 | 195407 | 90 | 34761427 |
Nocturia | 11.44 | 10.35 | 25 | 195389 | 10185 | 34751332 |
Blood testosterone decreased | 11.44 | 10.35 | 5 | 195409 | 4352 | 34757165 |
Endocardial fibrosis | 11.40 | 10.35 | 5 | 195409 | 30 | 34761487 |
Acid-base balance disorder mixed | 11.37 | 10.35 | 6 | 195408 | 57 | 34761460 |
Syringe issue | 11.34 | 10.35 | 9 | 195405 | 5655 | 34755862 |
Accident | 11.30 | 10.35 | 57 | 195357 | 4990 | 34756527 |
Nocardiosis | 11.25 | 10.35 | 4 | 195410 | 3947 | 34757570 |
Graft versus host disease in skin | 11.13 | 10.35 | 4 | 195410 | 3921 | 34757596 |
Angina unstable | 11.13 | 10.35 | 31 | 195383 | 11622 | 34749895 |
Illness | 11.03 | 10.35 | 120 | 195294 | 13409 | 34748108 |
No adverse event | 10.95 | 10.35 | 79 | 195335 | 22848 | 34738669 |
Protein urine | 10.91 | 10.35 | 19 | 195395 | 905 | 34760612 |
Hyperlipidaemia | 10.88 | 10.35 | 43 | 195371 | 14486 | 34747031 |
Sleep disorder due to a general medical condition | 10.83 | 10.35 | 8 | 195406 | 5213 | 34756304 |
Anion gap increased | 10.79 | 10.35 | 29 | 195385 | 1867 | 34759650 |
SJS-TEN overlap | 10.77 | 10.35 | 11 | 195403 | 309 | 34761208 |
Acute myeloid leukaemia | 10.76 | 10.35 | 59 | 195355 | 18211 | 34743306 |
Increased viscosity of upper respiratory secretion | 10.74 | 10.35 | 8 | 195406 | 145 | 34761372 |
Disturbance in attention | 10.72 | 10.35 | 93 | 195321 | 25852 | 34735665 |
Product use in unapproved indication | 10.71 | 10.35 | 542 | 194872 | 116957 | 34644560 |
Myasthenia gravis | 10.71 | 10.35 | 71 | 195343 | 6869 | 34754648 |
Injection site pruritus | 10.68 | 10.35 | 14 | 195400 | 6969 | 34754548 |
Kidney transplant rejection | 10.50 | 10.35 | 16 | 195398 | 7481 | 34754036 |
Blood pressure decreased | 10.48 | 10.35 | 369 | 195045 | 51146 | 34710371 |
Dissociative disorder | 10.44 | 10.35 | 13 | 195401 | 456 | 34761061 |
Infusion site discomfort | 10.43 | 10.35 | 9 | 195405 | 203 | 34761314 |
Adenocarcinoma of colon | 10.43 | 10.35 | 3 | 195411 | 3388 | 34758129 |
Renal cancer | 10.37 | 10.35 | 17 | 195397 | 7718 | 34753799 |
Proctalgia | 10.36 | 10.35 | 61 | 195353 | 5662 | 34755855 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Completed suicide | 3621.87 | 9.99 | 6402 | 567362 | 239365 | 78931259 |
Toxicity to various agents | 3451.70 | 9.99 | 8627 | 565137 | 412913 | 78757711 |
Exposure to toxic agent | 1336.59 | 9.99 | 829 | 572935 | 8329 | 79162295 |
Infusion related reaction | 1127.93 | 9.99 | 3932 | 569832 | 226305 | 78944319 |
Blood pressure fluctuation | 820.70 | 9.99 | 1617 | 572147 | 65528 | 79105096 |
Intentional overdose | 796.84 | 9.99 | 2105 | 571659 | 103855 | 79066769 |
Intentional product misuse | 749.85 | 9.99 | 1924 | 571840 | 93241 | 79077383 |
Acute hepatic failure | 737.44 | 9.99 | 994 | 572770 | 29119 | 79141505 |
Overdose | 699.08 | 9.99 | 2901 | 570863 | 181305 | 78989319 |
Rheumatoid arthritis | 394.84 | 9.99 | 2711 | 571053 | 205759 | 78964865 |
Hepatic cytolysis | 391.52 | 9.99 | 702 | 573062 | 26449 | 79144175 |
Metabolic acidosis | 361.34 | 9.99 | 1360 | 572404 | 81169 | 79089455 |
Sinusitis | 360.54 | 9.99 | 2526 | 571238 | 192975 | 78977649 |
Muscle injury | 342.97 | 9.99 | 943 | 572821 | 47618 | 79123006 |
Heart rate decreased | 341.04 | 9.99 | 1198 | 572566 | 69118 | 79101506 |
Duodenal ulcer perforation | 340.26 | 9.99 | 1150 | 572614 | 65061 | 79105563 |
Hepatotoxicity | 331.22 | 9.99 | 965 | 572799 | 50387 | 79120237 |
Helicobacter infection | 324.73 | 9.99 | 1172 | 572592 | 68532 | 79102092 |
Analgesic drug level increased | 321.54 | 9.99 | 229 | 573535 | 2949 | 79167675 |
Folliculitis | 314.33 | 9.99 | 995 | 572769 | 54385 | 79116239 |
Product dose omission issue | 302.30 | 9.99 | 851 | 572913 | 246686 | 78923938 |
Irritable bowel syndrome | 301.47 | 9.99 | 1060 | 572704 | 61181 | 79109443 |
Injection site pain | 297.20 | 9.99 | 297 | 573467 | 129541 | 79041083 |
Anion gap | 292.09 | 9.99 | 187 | 573577 | 1994 | 79168630 |
Anti-cyclic citrullinated peptide antibody positive | 284.69 | 9.99 | 1270 | 572494 | 81873 | 79088751 |
Blood pressure increased | 276.91 | 9.99 | 2525 | 571239 | 208835 | 78961789 |
Sleep disorder due to general medical condition, insomnia type | 275.63 | 9.99 | 813 | 572951 | 42743 | 79127881 |
Intentional product use issue | 261.59 | 9.99 | 1933 | 571831 | 150179 | 79020445 |
Drug abuse | 260.48 | 9.99 | 2033 | 571731 | 160658 | 79009966 |
Hepatic enzyme increased | 256.41 | 9.99 | 2215 | 571549 | 180395 | 78990229 |
Medication error | 254.51 | 9.99 | 1074 | 572690 | 67568 | 79103056 |
Nasopharyngitis | 248.01 | 9.99 | 2856 | 570908 | 251025 | 78919599 |
Pemphigus | 246.70 | 9.99 | 1388 | 572376 | 98194 | 79072430 |
Pericarditis | 244.57 | 9.99 | 1432 | 572332 | 102804 | 79067820 |
Hand deformity | 239.54 | 9.99 | 1421 | 572343 | 102498 | 79068126 |
Anaemia | 237.17 | 9.99 | 2054 | 571710 | 442961 | 78727663 |
Lower respiratory tract infection | 231.29 | 9.99 | 1658 | 572106 | 127562 | 79043062 |
Myocardial infarction | 225.47 | 9.99 | 632 | 573132 | 183497 | 78987127 |
Blood pressure diastolic abnormal | 221.99 | 9.99 | 452 | 573312 | 18750 | 79151874 |
Suicide attempt | 216.83 | 9.99 | 1173 | 572591 | 81759 | 79088865 |
Respiratory arrest | 214.55 | 9.99 | 902 | 572862 | 56648 | 79113976 |
Blister | 212.67 | 9.99 | 1531 | 572233 | 117945 | 79052679 |
Depressed level of consciousness | 212.17 | 9.99 | 1305 | 572459 | 95347 | 79075277 |
Coagulopathy | 209.90 | 9.99 | 653 | 573111 | 35353 | 79135271 |
Blood pressure systolic increased | 209.17 | 9.99 | 996 | 572768 | 65990 | 79104634 |
Diarrhoea | 207.77 | 9.99 | 4791 | 568973 | 875698 | 78294926 |
Glossodynia | 207.51 | 9.99 | 1364 | 572400 | 101973 | 79068651 |
Ill-defined disorder | 206.07 | 9.99 | 980 | 572784 | 64895 | 79105729 |
Blood pressure systolic abnormal | 202.97 | 9.99 | 409 | 573355 | 16838 | 79153786 |
Injection site erythema | 197.83 | 9.99 | 163 | 573601 | 78034 | 79092590 |
Wound | 192.69 | 9.99 | 1464 | 572300 | 114715 | 79055909 |
Drug interaction | 192.21 | 9.99 | 1984 | 571780 | 413199 | 78757425 |
Oxygen saturation decreased | 190.42 | 9.99 | 1583 | 572181 | 127464 | 79043160 |
Cardio-respiratory arrest | 189.96 | 9.99 | 1385 | 572379 | 107125 | 79063499 |
Discomfort | 187.53 | 9.99 | 1545 | 572219 | 124072 | 79046552 |
Drug ineffective | 187.05 | 9.99 | 6145 | 567619 | 1074768 | 78095856 |
Systemic lupus erythematosus | 180.29 | 9.99 | 1489 | 572275 | 119660 | 79050964 |
Drug resistance | 176.72 | 9.99 | 43 | 573721 | 42170 | 79128454 |
Wrong technique in product usage process | 175.98 | 9.99 | 163 | 573601 | 73712 | 79096912 |
Cardiac failure congestive | 174.88 | 9.99 | 488 | 573276 | 141914 | 79028710 |
Blood pressure diastolic decreased | 174.29 | 9.99 | 546 | 573218 | 29670 | 79140954 |
Impaired healing | 169.94 | 9.99 | 1147 | 572617 | 86508 | 79084116 |
Poisoning | 163.98 | 9.99 | 476 | 573288 | 24796 | 79145828 |
Weight increased | 161.10 | 9.99 | 2848 | 570916 | 274538 | 78896086 |
Cardiac failure | 157.71 | 9.99 | 577 | 573187 | 154265 | 79016359 |
Synovitis | 157.18 | 9.99 | 1718 | 572046 | 149016 | 79021608 |
Poisoning deliberate | 152.66 | 9.99 | 385 | 573379 | 18443 | 79152181 |
Throat irritation | 150.46 | 9.99 | 639 | 573125 | 40307 | 79130317 |
Pyroglutamic acidosis | 145.94 | 9.99 | 93 | 573671 | 983 | 79169641 |
Body temperature increased | 143.43 | 9.99 | 667 | 573097 | 43753 | 79126871 |
Sedation complication | 142.62 | 9.99 | 335 | 573429 | 15334 | 79155290 |
Joint swelling | 141.65 | 9.99 | 2888 | 570876 | 285758 | 78884866 |
Liver injury | 140.09 | 9.99 | 789 | 572975 | 55825 | 79114799 |
Cytokine release syndrome | 139.49 | 9.99 | 571 | 573193 | 35427 | 79135197 |
Device expulsion | 138.50 | 9.99 | 13 | 573751 | 25848 | 79144776 |
Hepatic necrosis | 134.67 | 9.99 | 238 | 573526 | 8862 | 79161762 |
Respiratory depression | 131.55 | 9.99 | 468 | 573296 | 27162 | 79143462 |
Accidental overdose | 126.81 | 9.99 | 593 | 573171 | 38988 | 79131636 |
Bone marrow failure | 126.24 | 9.99 | 109 | 573655 | 50998 | 79119626 |
Disease progression | 123.21 | 9.99 | 798 | 572966 | 183564 | 78987060 |
Pancytopenia | 120.36 | 9.99 | 699 | 573065 | 165046 | 79005578 |
Arthropathy | 119.91 | 9.99 | 1865 | 571899 | 175246 | 78995378 |
Psoriasis | 118.33 | 9.99 | 296 | 573468 | 89291 | 79081333 |
Creatinine renal clearance decreased | 117.65 | 9.99 | 352 | 573412 | 18650 | 79151974 |
Therapeutic product effect decreased | 116.52 | 9.99 | 1740 | 572024 | 162123 | 79008501 |
COVID-19 | 115.92 | 9.99 | 1684 | 572080 | 155990 | 79014634 |
Neutropenia | 114.83 | 9.99 | 1421 | 572343 | 286289 | 78884335 |
Renal impairment | 113.72 | 9.99 | 667 | 573097 | 157116 | 79013508 |
Swelling | 113.54 | 9.99 | 2190 | 571574 | 214521 | 78956103 |
Injection site pruritus | 113.46 | 9.99 | 83 | 573681 | 42200 | 79128424 |
Methaemoglobinaemia | 113.16 | 9.99 | 168 | 573596 | 5389 | 79165235 |
Suspected suicide | 112.95 | 9.99 | 241 | 573523 | 10335 | 79160289 |
Heart rate irregular | 112.43 | 9.99 | 500 | 573264 | 32179 | 79138445 |
Exposure via ingestion | 109.09 | 9.99 | 159 | 573605 | 5015 | 79165609 |
Injection site reaction | 108.28 | 9.99 | 141 | 573623 | 54644 | 79115980 |
Sopor | 108.08 | 9.99 | 51 | 573713 | 32959 | 79137665 |
Heart rate increased | 107.57 | 9.99 | 1335 | 572429 | 119389 | 79051235 |
Injection site bruising | 106.79 | 9.99 | 83 | 573681 | 40919 | 79129705 |
Osteonecrosis of jaw | 105.78 | 9.99 | 93 | 573671 | 43133 | 79127491 |
Injection site swelling | 104.20 | 9.99 | 111 | 573653 | 47021 | 79123603 |
Blood pressure diastolic increased | 103.25 | 9.99 | 283 | 573481 | 14259 | 79156365 |
Gastrointestinal disorder | 103.20 | 9.99 | 1338 | 572426 | 120867 | 79049757 |
Blood calcium decreased | 97.77 | 9.99 | 471 | 573293 | 31348 | 79139276 |
Coma | 96.21 | 9.99 | 1128 | 572636 | 99521 | 79071103 |
Body temperature decreased | 96.03 | 9.99 | 472 | 573292 | 31673 | 79138951 |
Coronary artery disease | 93.11 | 9.99 | 208 | 573556 | 65266 | 79105358 |
Contraindicated product administered | 91.17 | 9.99 | 1617 | 572147 | 155921 | 79014703 |
Hypersensitivity | 90.08 | 9.99 | 2498 | 571266 | 259741 | 78910883 |
Rheumatic fever | 89.65 | 9.99 | 425 | 573339 | 28100 | 79142524 |
Poor venous access | 89.49 | 9.99 | 311 | 573453 | 17838 | 79152786 |
Hospitalisation | 88.95 | 9.99 | 362 | 573402 | 93874 | 79076750 |
Product prescribing error | 86.86 | 9.99 | 117 | 573647 | 44696 | 79125928 |
Myelosuppression | 86.76 | 9.99 | 97 | 573667 | 40199 | 79130425 |
Cerebrovascular accident | 85.54 | 9.99 | 710 | 573054 | 154582 | 79016042 |
Anion gap abnormal | 85.01 | 9.99 | 55 | 573709 | 598 | 79170026 |
Infusion site extravasation | 84.37 | 9.99 | 209 | 573555 | 9899 | 79160725 |
Acute lung injury | 81.53 | 9.99 | 106 | 573658 | 2994 | 79167630 |
Decreased appetite | 79.52 | 9.99 | 1866 | 571898 | 340552 | 78830072 |
Malignant neoplasm progression | 78.46 | 9.99 | 614 | 573150 | 135376 | 79035248 |
Hepatic failure | 77.86 | 9.99 | 727 | 573037 | 60485 | 79110139 |
Dehydration | 77.43 | 9.99 | 1287 | 572477 | 246900 | 78923724 |
Therapy cessation | 75.96 | 9.99 | 95 | 573669 | 37467 | 79133157 |
Inappropriate schedule of product administration | 75.33 | 9.99 | 1366 | 572398 | 132262 | 79038362 |
Diabetes mellitus | 74.69 | 9.99 | 300 | 573464 | 78090 | 79092534 |
Hyperkalaemia | 73.96 | 9.99 | 500 | 573264 | 113898 | 79056726 |
Acute kidney injury | 73.50 | 9.99 | 3023 | 570741 | 516381 | 78654243 |
Infusion site pain | 73.47 | 9.99 | 247 | 573517 | 13929 | 79156695 |
Therapeutic product effect incomplete | 73.37 | 9.99 | 658 | 573106 | 140987 | 79029637 |
Dizziness | 72.58 | 9.99 | 3073 | 570691 | 523368 | 78647256 |
Neoplasm progression | 72.01 | 9.99 | 166 | 573598 | 51516 | 79119108 |
Neuropathy peripheral | 71.21 | 9.99 | 661 | 573103 | 140644 | 79029980 |
Hypotension | 69.62 | 9.99 | 3853 | 569911 | 436464 | 78734160 |
Leukopenia | 69.12 | 9.99 | 522 | 573242 | 115991 | 79054633 |
Ear pain | 69.09 | 9.99 | 439 | 573325 | 32430 | 79138194 |
Acute myocardial infarction | 68.34 | 9.99 | 303 | 573461 | 76733 | 79093891 |
Product substitution issue | 68.34 | 9.99 | 30 | 573734 | 20226 | 79150398 |
Prostate cancer | 67.42 | 9.99 | 84 | 573680 | 33184 | 79137440 |
Rheumatoid factor positive | 66.51 | 9.99 | 691 | 573073 | 59148 | 79111476 |
Atrial fibrillation | 66.45 | 9.99 | 1012 | 572752 | 196874 | 78973750 |
Substance abuse | 65.17 | 9.99 | 195 | 573569 | 10331 | 79160293 |
Injection site warmth | 64.13 | 9.99 | 14 | 573750 | 14793 | 79155831 |
Dyspnoea | 63.98 | 9.99 | 5304 | 568460 | 851721 | 78318903 |
Cerebral infarction | 63.40 | 9.99 | 147 | 573617 | 45529 | 79125095 |
Syncope | 63.27 | 9.99 | 909 | 572855 | 178540 | 78992084 |
Haematotoxicity | 62.67 | 9.99 | 17 | 573747 | 15502 | 79155122 |
Interstitial lung disease | 61.91 | 9.99 | 515 | 573249 | 112085 | 79058539 |
Alanine aminotransferase increased | 60.76 | 9.99 | 1566 | 572198 | 161004 | 79009620 |
Swollen joint count increased | 60.37 | 9.99 | 325 | 573439 | 22602 | 79148022 |
Infusion site swelling | 60.31 | 9.99 | 157 | 573607 | 7669 | 79162955 |
Infusion site pruritus | 60.03 | 9.99 | 107 | 573657 | 4011 | 79166613 |
Stomatitis | 60.01 | 9.99 | 1431 | 572333 | 145326 | 79025298 |
Cerebral haemorrhage | 59.95 | 9.99 | 213 | 573551 | 57460 | 79113164 |
Thrombocytopenia | 59.21 | 9.99 | 1454 | 572310 | 263805 | 78906819 |
Dyspnoea exertional | 59.09 | 9.99 | 375 | 573389 | 86698 | 79083926 |
Ear pruritus | 58.81 | 9.99 | 106 | 573658 | 4009 | 79166615 |
Cytomegalovirus infection | 58.59 | 9.99 | 138 | 573626 | 42506 | 79128118 |
Device issue | 57.54 | 9.99 | 66 | 573698 | 27042 | 79143582 |
Respiratory rate increased | 57.43 | 9.99 | 307 | 573457 | 21293 | 79149331 |
Gastrointestinal haemorrhage | 57.22 | 9.99 | 734 | 573030 | 146985 | 79023639 |
Oedema peripheral | 56.55 | 9.99 | 1382 | 572382 | 250906 | 78919718 |
Transient ischaemic attack | 56.53 | 9.99 | 192 | 573572 | 52503 | 79118121 |
Pyroglutamate increased | 56.46 | 9.99 | 44 | 573720 | 655 | 79169969 |
Therapeutic response shortened | 56.30 | 9.99 | 245 | 573519 | 15618 | 79155006 |
Injection site mass | 56.29 | 9.99 | 38 | 573726 | 20146 | 79150478 |
Injection site haemorrhage | 55.82 | 9.99 | 71 | 573693 | 27799 | 79142825 |
Feeling abnormal | 55.21 | 9.99 | 809 | 572955 | 158390 | 79012234 |
Diabetic ketoacidosis | 54.82 | 9.99 | 101 | 573663 | 34021 | 79136603 |
Labelled drug-drug interaction medication error | 54.80 | 9.99 | 71 | 573693 | 27579 | 79143045 |
Sedation | 54.28 | 9.99 | 592 | 573172 | 51303 | 79119321 |
Hypocalcaemia | 54.18 | 9.99 | 181 | 573583 | 49743 | 79120881 |
Injection site rash | 53.94 | 9.99 | 31 | 573733 | 17923 | 79152701 |
Electric shock | 53.82 | 9.99 | 58 | 573706 | 1336 | 79169288 |
Pathogen resistance | 53.77 | 9.99 | 18 | 573746 | 14324 | 79156300 |
Neutrophil percentage increased | 53.75 | 9.99 | 110 | 573654 | 4579 | 79166045 |
Body temperature fluctuation | 53.05 | 9.99 | 97 | 573667 | 3710 | 79166914 |
Red blood cell sedimentation rate abnormal | 52.63 | 9.99 | 44 | 573720 | 20919 | 79149705 |
Full blood count abnormal | 52.45 | 9.99 | 135 | 573629 | 40339 | 79130285 |
Infusion site erythema | 51.86 | 9.99 | 168 | 573596 | 9292 | 79161332 |
Urine abnormality | 51.59 | 9.99 | 153 | 573611 | 8066 | 79162558 |
Post transplant lymphoproliferative disorder | 51.39 | 9.99 | 10 | 573754 | 11454 | 79159170 |
Oesophageal carcinoma | 51.12 | 9.99 | 9 | 573755 | 11075 | 79159549 |
Weight fluctuation | 50.73 | 9.99 | 192 | 573572 | 11483 | 79159141 |
Hyperlipidaemia | 50.70 | 9.99 | 68 | 573696 | 26025 | 79144599 |
Contusion | 50.69 | 9.99 | 1416 | 572348 | 147360 | 79023264 |
Epistaxis | 50.59 | 9.99 | 535 | 573229 | 110980 | 79059644 |
Urine leukocyte esterase positive | 50.52 | 9.99 | 99 | 573665 | 3992 | 79166632 |
Bladder cancer | 50.25 | 9.99 | 40 | 573724 | 19486 | 79151138 |
Osteonecrosis | 49.99 | 9.99 | 92 | 573672 | 31003 | 79139621 |
Crystal urine present | 49.40 | 9.99 | 69 | 573695 | 2091 | 79168533 |
Renal failure | 49.19 | 9.99 | 1086 | 572678 | 199882 | 78970742 |
Product quality issue | 48.92 | 9.99 | 107 | 573657 | 33833 | 79136791 |
Septic shock | 48.74 | 9.99 | 607 | 573157 | 122194 | 79048430 |
Surgery | 48.31 | 9.99 | 102 | 573662 | 32664 | 79137960 |
Device difficult to use | 48.12 | 9.99 | 18 | 573746 | 13367 | 79157257 |
Paraesthesia | 48.12 | 9.99 | 936 | 572828 | 175387 | 78995237 |
Therapy interrupted | 47.53 | 9.99 | 96 | 573668 | 31245 | 79139379 |
Product storage error | 47.37 | 9.99 | 29 | 573735 | 16197 | 79154427 |
Palmar-plantar erythrodysaesthesia syndrome | 47.32 | 9.99 | 105 | 573659 | 33029 | 79137595 |
Systemic infection | 47.04 | 9.99 | 7 | 573757 | 9745 | 79160879 |
Visual acuity reduced | 46.66 | 9.99 | 88 | 573676 | 29381 | 79141243 |
Cognitive disorder | 46.38 | 9.99 | 734 | 573030 | 69192 | 79101432 |
Arthralgia | 46.13 | 9.99 | 4743 | 569021 | 567060 | 78603564 |
White blood cells urine positive | 45.92 | 9.99 | 121 | 573643 | 5954 | 79164670 |
Blood parathyroid hormone decreased | 45.56 | 9.99 | 10 | 573754 | 10526 | 79160098 |
Asthenia | 45.14 | 9.99 | 3122 | 570642 | 508567 | 78662057 |
Lymphocyte percentage decreased | 44.86 | 9.99 | 106 | 573658 | 4870 | 79165754 |
Device malfunction | 44.69 | 9.99 | 53 | 573711 | 21395 | 79149229 |
Electrocardiogram QT prolonged | 44.58 | 9.99 | 425 | 573339 | 89961 | 79080663 |
Immune reconstitution inflammatory syndrome | 44.37 | 9.99 | 22 | 573742 | 13819 | 79156805 |
Platelet count decreased | 44.25 | 9.99 | 1064 | 572700 | 193600 | 78977024 |
Loss of consciousness | 44.17 | 9.99 | 897 | 572867 | 167046 | 79003578 |
Pharyngeal paraesthesia | 43.98 | 9.99 | 74 | 573690 | 2647 | 79167977 |
Posterior reversible encephalopathy syndrome | 43.83 | 9.99 | 76 | 573688 | 26205 | 79144419 |
Epilepsy | 43.75 | 9.99 | 149 | 573615 | 40711 | 79129913 |
Unintentional medical device removal | 43.74 | 9.99 | 3 | 573761 | 7709 | 79162915 |
Orthostatic hypotension | 43.70 | 9.99 | 606 | 573158 | 55558 | 79115066 |
Mucosal inflammation | 43.69 | 9.99 | 341 | 573423 | 75239 | 79095385 |
Muscle spasms | 43.39 | 9.99 | 942 | 572822 | 173788 | 78996836 |
Myelodysplastic syndrome | 43.29 | 9.99 | 96 | 573668 | 30205 | 79140419 |
Mobility decreased | 43.08 | 9.99 | 1168 | 572596 | 121007 | 79049617 |
White blood cell count decreased | 42.84 | 9.99 | 1029 | 572735 | 187259 | 78983365 |
Muscle spasticity | 42.79 | 9.99 | 283 | 573481 | 21192 | 79149432 |
Status epilepticus | 42.14 | 9.99 | 72 | 573692 | 24969 | 79145655 |
Sudden infant death syndrome | 42.09 | 9.99 | 26 | 573738 | 259 | 79170365 |
Haematuria | 41.96 | 9.99 | 306 | 573458 | 68530 | 79102094 |
Thrombotic microangiopathy | 41.85 | 9.99 | 50 | 573714 | 20119 | 79150505 |
Fibromyalgia | 41.41 | 9.99 | 672 | 573092 | 63668 | 79106956 |
Second primary malignancy | 41.40 | 9.99 | 26 | 573738 | 14324 | 79156300 |
Gait disturbance | 41.37 | 9.99 | 1156 | 572608 | 206350 | 78964274 |
Multiple-drug resistance | 40.96 | 9.99 | 7 | 573757 | 8801 | 79161823 |
Drug intolerance | 40.85 | 9.99 | 2307 | 571457 | 261812 | 78908812 |
Nausea | 40.84 | 9.99 | 6155 | 567609 | 951041 | 78219583 |
Vision blurred | 40.70 | 9.99 | 527 | 573237 | 105371 | 79065253 |
Lactic acidosis | 40.41 | 9.99 | 318 | 573446 | 70041 | 79100583 |
Injection site urticaria | 40.20 | 9.99 | 21 | 573743 | 12805 | 79157819 |
Myalgia | 39.93 | 9.99 | 1023 | 572741 | 184618 | 78986006 |
Infusion site bruising | 39.61 | 9.99 | 74 | 573690 | 2878 | 79167746 |
Anticipatory anxiety | 39.47 | 9.99 | 46 | 573718 | 1158 | 79169466 |
Acute myeloid leukaemia | 39.27 | 9.99 | 104 | 573660 | 30781 | 79139843 |
Aspergillus infection | 39.23 | 9.99 | 48 | 573716 | 19113 | 79151511 |
Dry skin | 39.20 | 9.99 | 307 | 573457 | 67688 | 79102936 |
Drug use disorder | 39.03 | 9.99 | 144 | 573620 | 8507 | 79162117 |
Seizure | 38.93 | 9.99 | 1047 | 572717 | 187787 | 78982837 |
Underdose | 38.91 | 9.99 | 116 | 573648 | 33035 | 79137589 |
Basal cell carcinoma | 38.86 | 9.99 | 138 | 573626 | 37237 | 79133387 |
Peripheral swelling | 38.64 | 9.99 | 2339 | 571425 | 267278 | 78903346 |
Abortion spontaneous | 38.56 | 9.99 | 98 | 573666 | 29409 | 79141215 |
Fall | 38.53 | 9.99 | 3003 | 570761 | 484626 | 78685998 |
Cytopenia | 37.72 | 9.99 | 55 | 573709 | 20328 | 79150296 |
Night sweats | 37.70 | 9.99 | 555 | 573209 | 51540 | 79119084 |
Injection site induration | 37.38 | 9.99 | 12 | 573752 | 9807 | 79160817 |
Graft versus host disease | 37.16 | 9.99 | 32 | 573732 | 14994 | 79155630 |
Breast cancer stage I | 36.88 | 9.99 | 3 | 573761 | 6697 | 79163927 |
Blood pH decreased | 36.81 | 9.99 | 95 | 573669 | 4616 | 79166008 |
Hypokalaemia | 36.79 | 9.99 | 773 | 572991 | 143267 | 79027357 |
Drug-induced liver injury | 36.23 | 9.99 | 673 | 573091 | 65444 | 79105180 |
Bursitis | 36.16 | 9.99 | 406 | 573358 | 35438 | 79135186 |
Jaundice cholestatic | 36.09 | 9.99 | 169 | 573595 | 11115 | 79159509 |
Pain | 35.69 | 9.99 | 5674 | 568090 | 698128 | 78472496 |
Drug ineffective for unapproved indication | 35.62 | 9.99 | 219 | 573545 | 51019 | 79119605 |
Disturbance in attention | 35.39 | 9.99 | 217 | 573547 | 50584 | 79120040 |
Granuloma skin | 35.30 | 9.99 | 11 | 573753 | 9163 | 79161461 |
Hypomania | 35.24 | 9.99 | 127 | 573637 | 7417 | 79163207 |
Infusion site mass | 35.11 | 9.99 | 50 | 573714 | 1543 | 79169081 |
Urticaria | 35.00 | 9.99 | 1649 | 572115 | 183552 | 78987072 |
Product use in unapproved indication | 34.92 | 9.99 | 1459 | 572305 | 248900 | 78921724 |
Alopecia | 34.64 | 9.99 | 2015 | 571749 | 229340 | 78941284 |
Blood glucose increased | 34.59 | 9.99 | 600 | 573164 | 114375 | 79056249 |
Facet joint syndrome | 34.50 | 9.99 | 167 | 573597 | 11135 | 79159489 |
Sexual dysfunction | 34.32 | 9.99 | 7 | 573757 | 7756 | 79162868 |
International normalised ratio increased | 34.28 | 9.99 | 825 | 572939 | 83896 | 79086728 |
Hepatic cirrhosis | 34.25 | 9.99 | 132 | 573632 | 34774 | 79135850 |
Therapeutic response decreased | 33.98 | 9.99 | 312 | 573452 | 66541 | 79104083 |
Aspartate aminotransferase increased | 33.81 | 9.99 | 1268 | 572496 | 137373 | 79033251 |
Hypertensive crisis | 33.79 | 9.99 | 61 | 573703 | 20709 | 79149915 |
Cardiac failure chronic | 33.78 | 9.99 | 19 | 573745 | 11116 | 79159508 |
Haemorrhage | 33.72 | 9.99 | 457 | 573307 | 90661 | 79079963 |
Product monitoring error | 33.70 | 9.99 | 11 | 573753 | 8895 | 79161729 |
Suicidal ideation | 33.51 | 9.99 | 369 | 573395 | 75971 | 79094653 |
Urinary sediment present | 33.33 | 9.99 | 63 | 573701 | 2472 | 79168152 |
Confusional state | 33.23 | 9.99 | 2688 | 571076 | 315309 | 78855315 |
Death | 33.17 | 9.99 | 4605 | 569159 | 561909 | 78608715 |
Haematochezia | 33.01 | 9.99 | 438 | 573326 | 87207 | 79083417 |
Hypercalcaemia | 32.97 | 9.99 | 153 | 573611 | 38277 | 79132347 |
Specific gravity urine decreased | 32.97 | 9.99 | 36 | 573728 | 842 | 79169782 |
Hyponatraemia | 32.88 | 9.99 | 1001 | 572763 | 176847 | 78993777 |
Rash pruritic | 32.74 | 9.99 | 343 | 573421 | 71286 | 79099338 |
Joint range of motion decreased | 32.68 | 9.99 | 375 | 573389 | 32907 | 79137717 |
Maternal exposure during pregnancy | 32.63 | 9.99 | 1246 | 572518 | 135292 | 79035332 |
Transplant rejection | 32.60 | 9.99 | 56 | 573708 | 19381 | 79151243 |
Cardiac failure acute | 32.25 | 9.99 | 54 | 573710 | 18875 | 79151749 |
Angina unstable | 32.18 | 9.99 | 43 | 573721 | 16484 | 79154140 |
Renal cortical necrosis | 32.02 | 9.99 | 24 | 573740 | 336 | 79170288 |
Unresponsive to stimuli | 32.02 | 9.99 | 572 | 573192 | 55216 | 79115408 |
Device dislocation | 31.85 | 9.99 | 89 | 573675 | 25881 | 79144743 |
Injury | 31.77 | 9.99 | 756 | 573008 | 76740 | 79093884 |
Ventricular tachycardia | 31.41 | 9.99 | 175 | 573589 | 41760 | 79128864 |
Breast cancer female | 31.40 | 9.99 | 22 | 573742 | 11439 | 79159185 |
Mydriasis | 31.31 | 9.99 | 226 | 573538 | 17417 | 79153207 |
Diplopia | 31.29 | 9.99 | 129 | 573635 | 33337 | 79137287 |
Brain death | 31.29 | 9.99 | 101 | 573663 | 5576 | 79165048 |
Panniculitis | 31.02 | 9.99 | 26 | 573738 | 12345 | 79158279 |
Deep vein thrombosis | 30.85 | 9.99 | 649 | 573115 | 120270 | 79050354 |
Lymphocyte count decreased | 30.84 | 9.99 | 495 | 573269 | 46794 | 79123830 |
Spinal stenosis | 30.83 | 9.99 | 41 | 573723 | 15750 | 79154874 |
Acidosis | 30.50 | 9.99 | 245 | 573519 | 19517 | 79151107 |
Pain in extremity | 30.50 | 9.99 | 2234 | 571530 | 362304 | 78808320 |
Toxicologic test abnormal | 30.44 | 9.99 | 43 | 573721 | 1317 | 79169307 |
Memory impairment | 30.21 | 9.99 | 594 | 573170 | 111140 | 79059484 |
Anion gap increased | 30.08 | 9.99 | 76 | 573688 | 3644 | 79166980 |
Full blood count decreased | 29.95 | 9.99 | 96 | 573668 | 26723 | 79143901 |
Extrapyramidal disorder | 29.88 | 9.99 | 75 | 573689 | 22604 | 79148020 |
Hypomagnesaemia | 29.83 | 9.99 | 206 | 573558 | 46705 | 79123919 |
Multiple drug therapy | 29.59 | 9.99 | 80 | 573684 | 3998 | 79166626 |
Skin necrosis | 29.53 | 9.99 | 53 | 573711 | 18034 | 79152590 |
Neurotoxicity | 29.38 | 9.99 | 127 | 573637 | 32391 | 79138233 |
Depression | 29.25 | 9.99 | 1268 | 572496 | 215522 | 78955102 |
Congestive cardiomyopathy | 29.24 | 9.99 | 25 | 573739 | 11755 | 79158869 |
Incorrect drug administration rate | 29.23 | 9.99 | 79 | 573685 | 3947 | 79166677 |
Drug dose omission by device | 28.99 | 9.99 | 5 | 573759 | 6245 | 79164379 |
Chronic kidney disease | 28.94 | 9.99 | 320 | 573444 | 65834 | 79104790 |
Fixed eruption | 28.92 | 9.99 | 65 | 573699 | 2889 | 79167735 |
Colorectal cancer | 28.86 | 9.99 | 13 | 573751 | 8634 | 79161990 |
Multiple sclerosis relapse | 28.77 | 9.99 | 206 | 573558 | 46327 | 79124297 |
Gastric cancer | 28.61 | 9.99 | 19 | 573745 | 10160 | 79160464 |
Akathisia | 28.45 | 9.99 | 32 | 573732 | 13227 | 79157397 |
Device leakage | 28.24 | 9.99 | 22 | 573742 | 10834 | 79159790 |
Haemolysis | 28.10 | 9.99 | 173 | 573591 | 12639 | 79157985 |
Skin exfoliation | 28.06 | 9.99 | 257 | 573507 | 54843 | 79115781 |
Deep vein thrombosis postoperative | 28.03 | 9.99 | 152 | 573612 | 10600 | 79160024 |
Infusion site haemorrhage | 28.02 | 9.99 | 74 | 573690 | 3646 | 79166978 |
Polyneuropathy | 27.99 | 9.99 | 85 | 573679 | 24066 | 79146558 |
Dermatitis atopic | 27.95 | 9.99 | 19 | 573745 | 10037 | 79160587 |
Renal cancer | 27.92 | 9.99 | 28 | 573736 | 12198 | 79158426 |
Torsade de pointes | 27.74 | 9.99 | 61 | 573703 | 19251 | 79151373 |
Drug withdrawal syndrome | 27.60 | 9.99 | 142 | 573622 | 34576 | 79136048 |
Pneumocystis jirovecii pneumonia | 27.55 | 9.99 | 130 | 573634 | 32378 | 79138246 |
Pruritus | 27.54 | 9.99 | 3243 | 570521 | 391405 | 78779219 |
Cardiac arrest | 27.52 | 9.99 | 1508 | 572256 | 170588 | 79000036 |
SARS-CoV-2 test positive | 27.48 | 9.99 | 161 | 573603 | 11555 | 79159069 |
Transplant dysfunction | 27.18 | 9.99 | 9 | 573755 | 7212 | 79163412 |
Blood cholesterol increased | 27.16 | 9.99 | 792 | 572972 | 82928 | 79087696 |
Metastases to lymph nodes | 27.13 | 9.99 | 21 | 573743 | 10376 | 79160248 |
Myopathy | 27.10 | 9.99 | 68 | 573696 | 20495 | 79150129 |
Infection | 26.85 | 9.99 | 2053 | 571711 | 239659 | 78930965 |
Red blood cell sedimentation rate | 26.83 | 9.99 | 4 | 573760 | 5561 | 79165063 |
Appendicolith | 26.57 | 9.99 | 127 | 573637 | 8424 | 79162200 |
Cardiac disorder | 26.47 | 9.99 | 324 | 573440 | 65433 | 79105191 |
Tremor | 26.35 | 9.99 | 979 | 572785 | 169104 | 79001520 |
Multiple allergies | 26.01 | 9.99 | 146 | 573618 | 10314 | 79160310 |
Subdural haematoma | 25.89 | 9.99 | 127 | 573637 | 31307 | 79139317 |
Graft versus host disease in skin | 25.78 | 9.99 | 6 | 573758 | 6067 | 79164557 |
General physical health deterioration | 25.78 | 9.99 | 1670 | 572094 | 273568 | 78897056 |
Drug screen positive | 25.76 | 9.99 | 99 | 573665 | 5964 | 79164660 |
Wound infection | 25.69 | 9.99 | 275 | 573489 | 23716 | 79146908 |
Bilirubin urine present | 25.69 | 9.99 | 21 | 573743 | 336 | 79170288 |
Coronary arterial stent insertion | 25.60 | 9.99 | 6 | 573758 | 6038 | 79164586 |
Analgesic drug level above therapeutic | 25.60 | 9.99 | 24 | 573740 | 465 | 79170159 |
Skin toxicity | 25.49 | 9.99 | 14 | 573750 | 8300 | 79162324 |
Bronchopulmonary aspergillosis | 25.46 | 9.99 | 79 | 573685 | 22215 | 79148409 |
Incorrect dose administered by device | 25.45 | 9.99 | 3 | 573761 | 4986 | 79165638 |
Lip dry | 25.37 | 9.99 | 194 | 573570 | 15224 | 79155400 |
Nocardiosis | 25.36 | 9.99 | 5 | 573759 | 5674 | 79164950 |
Cytomegalovirus viraemia | 25.33 | 9.99 | 33 | 573731 | 12788 | 79157836 |
Sputum culture positive | 25.28 | 9.99 | 72 | 573692 | 3709 | 79166915 |
Accidental exposure to product by child | 24.95 | 9.99 | 61 | 573703 | 2865 | 79167759 |
Gynaecomastia | 24.94 | 9.99 | 12 | 573752 | 7669 | 79162955 |
Thinking abnormal | 24.86 | 9.99 | 35 | 573729 | 13126 | 79157498 |
Metastases to lung | 24.77 | 9.99 | 59 | 573705 | 18104 | 79152520 |
Prothrombin time prolonged | 24.73 | 9.99 | 207 | 573557 | 16692 | 79153932 |
Rhabdomyolysis | 24.73 | 9.99 | 559 | 573205 | 102572 | 79068052 |
Acute graft versus host disease | 24.72 | 9.99 | 22 | 573742 | 10145 | 79160479 |
Bone pain | 24.64 | 9.99 | 269 | 573495 | 55473 | 79115151 |
Anti-cyclic citrullinated peptide antibody | 24.41 | 9.99 | 95 | 573669 | 5757 | 79164867 |
COVID-19 pneumonia | 24.39 | 9.99 | 316 | 573448 | 28533 | 79142091 |
Generalised bullous fixed drug eruption | 24.35 | 9.99 | 16 | 573748 | 179 | 79170445 |
Loss of personal independence in daily activities | 24.32 | 9.99 | 557 | 573207 | 102023 | 79068601 |
Renal papillary necrosis | 24.25 | 9.99 | 22 | 573742 | 408 | 79170216 |
Abdominal discomfort | 24.21 | 9.99 | 2107 | 571657 | 248620 | 78922004 |
Forced expiratory volume decreased | 24.19 | 9.99 | 13 | 573751 | 7801 | 79162823 |
Maternal exposure timing unspecified | 24.14 | 9.99 | 94 | 573670 | 5698 | 79164926 |
Oral pruritus | 24.11 | 9.99 | 54 | 573710 | 2394 | 79168230 |
Dyskinesia | 24.05 | 9.99 | 206 | 573558 | 44567 | 79126057 |
Intervertebral discitis | 24.03 | 9.99 | 83 | 573681 | 4745 | 79165879 |
Hypertriglyceridaemia | 23.95 | 9.99 | 34 | 573730 | 12706 | 79157918 |
Clostridium test positive | 23.92 | 9.99 | 101 | 573663 | 6353 | 79164271 |
Hepatocellular carcinoma | 23.82 | 9.99 | 18 | 573746 | 9003 | 79161621 |
No adverse event | 23.80 | 9.99 | 163 | 573601 | 37029 | 79133595 |
Mitral valve incompetence | 23.76 | 9.99 | 115 | 573649 | 28450 | 79142174 |
Epstein-Barr virus infection | 23.76 | 9.99 | 42 | 573722 | 14374 | 79156250 |
Pulmonary hypertension | 23.74 | 9.99 | 226 | 573538 | 47854 | 79122770 |
Blood triglycerides increased | 23.71 | 9.99 | 75 | 573689 | 20965 | 79149659 |
Thrombosis | 23.68 | 9.99 | 444 | 573320 | 83656 | 79086968 |
Red blood cells urine positive | 23.57 | 9.99 | 84 | 573680 | 4879 | 79165745 |
Venoocclusive liver disease | 23.56 | 9.99 | 30 | 573734 | 11741 | 79158883 |
Bacterial test | 23.52 | 9.99 | 36 | 573728 | 1187 | 79169437 |
Ageusia | 23.51 | 9.99 | 53 | 573711 | 16579 | 79154045 |
Neuroleptic malignant syndrome | 23.48 | 9.99 | 110 | 573654 | 27449 | 79143175 |
Brain stem glioma | 23.41 | 9.99 | 16 | 573748 | 192 | 79170432 |
Hepatitis fulminant | 23.40 | 9.99 | 109 | 573655 | 7153 | 79163471 |
Drug level below therapeutic | 23.40 | 9.99 | 135 | 573629 | 9635 | 79160989 |
Iron deficiency anaemia | 23.36 | 9.99 | 100 | 573664 | 25572 | 79145052 |
Diffuse large B-cell lymphoma | 23.26 | 9.99 | 32 | 573732 | 12117 | 79158507 |
Obstructive airways disorder | 23.17 | 9.99 | 132 | 573632 | 31327 | 79139297 |
Melaena | 23.03 | 9.99 | 304 | 573460 | 60586 | 79110038 |
Respiratory failure | 23 | 9.99 | 1065 | 572699 | 179846 | 78990778 |
Right ventricular failure | 22.96 | 9.99 | 89 | 573675 | 23408 | 79147216 |
Drug hypersensitivity | 22.92 | 9.99 | 1845 | 571919 | 297071 | 78873553 |
Tachycardia | 22.85 | 9.99 | 1528 | 572236 | 176240 | 78994384 |
Treatment noncompliance | 22.80 | 9.99 | 253 | 573511 | 52015 | 79118609 |
Visual impairment | 22.77 | 9.99 | 497 | 573267 | 91634 | 79078990 |
Pulmonary embolism | 22.74 | 9.99 | 1006 | 572758 | 170648 | 78999976 |
Adjustment disorder with depressed mood | 22.71 | 9.99 | 127 | 573637 | 8959 | 79161665 |
Dysarthria | 22.61 | 9.99 | 346 | 573418 | 67276 | 79103348 |
Urine analysis abnormal | 22.61 | 9.99 | 100 | 573664 | 6420 | 79164204 |
Vital capacity decreased | 22.49 | 9.99 | 44 | 573720 | 1772 | 79168852 |
Osmolar gap | 22.37 | 9.99 | 15 | 573749 | 174 | 79170450 |
Prostatic specific antigen increased | 22.36 | 9.99 | 25 | 573739 | 10361 | 79160263 |
Glycosylated haemoglobin increased | 22.17 | 9.99 | 68 | 573696 | 19192 | 79151432 |
Tardive dyskinesia | 22.15 | 9.99 | 26 | 573738 | 10545 | 79160079 |
Cystitis haemorrhagic | 22.12 | 9.99 | 20 | 573744 | 9152 | 79161472 |
Coronary artery bypass | 22.05 | 9.99 | 8 | 573756 | 6054 | 79164570 |
White coat hypertension | 21.99 | 9.99 | 29 | 573735 | 831 | 79169793 |
Hepatic cancer | 21.95 | 9.99 | 26 | 573738 | 10503 | 79160121 |
Angina pectoris | 21.94 | 9.99 | 252 | 573512 | 51480 | 79119144 |
Actinic keratosis | 21.93 | 9.99 | 8 | 573756 | 6034 | 79164590 |
Hallucination | 21.93 | 9.99 | 460 | 573304 | 85285 | 79085339 |
Acute graft versus host disease in skin | 21.92 | 9.99 | 14 | 573750 | 7644 | 79162980 |
Varicella zoster virus infection | 21.86 | 9.99 | 3 | 573761 | 4438 | 79166186 |
Therapeutic response unexpected | 21.85 | 9.99 | 72 | 573692 | 19874 | 79150750 |
Prothrombin time ratio decreased | 21.83 | 9.99 | 30 | 573734 | 895 | 79169729 |
Withdrawal syndrome | 21.82 | 9.99 | 109 | 573655 | 26745 | 79143879 |
Ischaemic stroke | 21.80 | 9.99 | 144 | 573620 | 32987 | 79137637 |
Hypothermia | 21.75 | 9.99 | 255 | 573509 | 22491 | 79148133 |
Kidney transplant rejection | 21.69 | 9.99 | 25 | 573739 | 10221 | 79160403 |
Injection site discolouration | 21.68 | 9.99 | 14 | 573750 | 7600 | 79163024 |
Ketoacidosis | 21.62 | 9.99 | 15 | 573749 | 7839 | 79162785 |
BK virus infection | 21.47 | 9.99 | 19 | 573745 | 8785 | 79161839 |
Infusion site discomfort | 21.46 | 9.99 | 37 | 573727 | 1350 | 79169274 |
Chronic graft versus host disease | 21.41 | 9.99 | 11 | 573753 | 6770 | 79163854 |
Immunosuppressant drug level increased | 21.39 | 9.99 | 20 | 573744 | 9007 | 79161617 |
Lung neoplasm malignant | 21.35 | 9.99 | 115 | 573649 | 27677 | 79142947 |
Metastases to liver | 21.29 | 9.99 | 118 | 573646 | 28196 | 79142428 |
Aphasia | 21.27 | 9.99 | 224 | 573540 | 46508 | 79124116 |
Lipodystrophy acquired | 21.10 | 9.99 | 3 | 573761 | 4322 | 79166302 |
Pancreatic carcinoma | 21.09 | 9.99 | 41 | 573723 | 13536 | 79157088 |
Tricuspid valve incompetence | 21.02 | 9.99 | 72 | 573692 | 19640 | 79150984 |
Flushing | 20.96 | 9.99 | 805 | 572959 | 87463 | 79083161 |
Fear of injection | 20.94 | 9.99 | 14 | 573750 | 7460 | 79163164 |
Pulmonary arterial hypertension | 20.91 | 9.99 | 119 | 573645 | 28247 | 79142377 |
Toxic epidermal necrolysis | 20.81 | 9.99 | 443 | 573321 | 44138 | 79126486 |
Soft tissue disorder | 20.71 | 9.99 | 64 | 573700 | 3451 | 79167173 |
Hepatitis B reactivation | 20.68 | 9.99 | 9 | 573755 | 6099 | 79164525 |
Low density lipoprotein increased | 20.56 | 9.99 | 19 | 573745 | 8603 | 79162021 |
Graft versus host disease in gastrointestinal tract | 20.53 | 9.99 | 10 | 573754 | 6346 | 79164278 |
Cardiovascular disorder | 20.49 | 9.99 | 64 | 573700 | 17961 | 79152663 |
Hepatitis acute | 20.47 | 9.99 | 186 | 573578 | 15356 | 79155268 |
Fluid retention | 20.45 | 9.99 | 366 | 573398 | 69443 | 79101181 |
Electrolyte imbalance | 20.43 | 9.99 | 134 | 573630 | 30747 | 79139877 |
Fracture | 20.40 | 9.99 | 84 | 573680 | 21717 | 79148907 |
Bundle branch block left | 20.40 | 9.99 | 32 | 573732 | 11481 | 79159143 |
Tendonitis | 20.37 | 9.99 | 95 | 573669 | 23735 | 79146889 |
Pyrexia | 20.36 | 9.99 | 5334 | 568430 | 673375 | 78497249 |
Macular oedema | 20.29 | 9.99 | 7 | 573757 | 5467 | 79165157 |
Product complaint | 20.15 | 9.99 | 41 | 573723 | 13308 | 79157316 |
Aplasia pure red cell | 20.10 | 9.99 | 16 | 573748 | 7794 | 79162830 |
Exposure to SARS-CoV-2 | 20.03 | 9.99 | 45 | 573719 | 1999 | 79168625 |
Cardiomyopathy | 19.99 | 9.99 | 123 | 573641 | 28651 | 79141973 |
Genital haemorrhage | 19.96 | 9.99 | 10 | 573754 | 6245 | 79164379 |
Red cell distribution width increased | 19.87 | 9.99 | 182 | 573582 | 15060 | 79155564 |
Urine bilirubin decreased | 19.81 | 9.99 | 13 | 573751 | 145 | 79170479 |
Ear infection | 19.74 | 9.99 | 353 | 573411 | 34079 | 79136545 |
Erectile dysfunction | 19.71 | 9.99 | 48 | 573716 | 14616 | 79156008 |
Blood potassium decreased | 19.56 | 9.99 | 227 | 573537 | 46285 | 79124339 |
Sinus node dysfunction | 19.54 | 9.99 | 16 | 573748 | 7685 | 79162939 |
Autoimmune disorder | 19.49 | 9.99 | 194 | 573570 | 16418 | 79154206 |
Circulatory collapse | 19.48 | 9.99 | 175 | 573589 | 37493 | 79133131 |
Hypocoagulable state | 19.47 | 9.99 | 46 | 573718 | 2113 | 79168511 |
Lymphoproliferative disorder | 19.45 | 9.99 | 8 | 573756 | 5607 | 79165017 |
Disease recurrence | 19.44 | 9.99 | 213 | 573551 | 43896 | 79126728 |
Acute coronary syndrome | 19.42 | 9.99 | 82 | 573682 | 21051 | 79149573 |
Hepatitis C | 19.42 | 9.99 | 35 | 573729 | 11890 | 79158734 |
Hepatic encephalopathy | 19.30 | 9.99 | 262 | 573502 | 23904 | 79146720 |
Hypothyroidism | 19.30 | 9.99 | 263 | 573501 | 52129 | 79118495 |
Respiratory disorder | 19.12 | 9.99 | 440 | 573324 | 44416 | 79126208 |
Disturbance in social behaviour | 19.05 | 9.99 | 6 | 573758 | 4964 | 79165660 |
Enthesopathy | 18.97 | 9.99 | 34 | 573730 | 11574 | 79159050 |
Carotid artery stenosis | 18.94 | 9.99 | 21 | 573743 | 8737 | 79161887 |
Fungal rhinitis | 18.89 | 9.99 | 10 | 573754 | 72 | 79170552 |
Sensitivity to weather change | 18.87 | 9.99 | 18 | 573746 | 8029 | 79162595 |
Skin lesion | 18.87 | 9.99 | 201 | 573563 | 41643 | 79128981 |
Skin ulcer | 18.82 | 9.99 | 275 | 573489 | 53875 | 79116749 |
Gestational diabetes | 18.72 | 9.99 | 11 | 573753 | 6282 | 79164342 |
Musculoskeletal stiffness | 18.69 | 9.99 | 1482 | 572282 | 173526 | 78997098 |
COVID-19 immunisation | 18.68 | 9.99 | 35 | 573729 | 1364 | 79169260 |
Asthma | 18.66 | 9.99 | 788 | 572976 | 134307 | 79036317 |
Lymphadenopathy | 18.65 | 9.99 | 270 | 573494 | 52977 | 79117647 |
Speech disorder | 18.40 | 9.99 | 278 | 573486 | 54167 | 79116457 |
Therapy partial responder | 18.24 | 9.99 | 64 | 573700 | 17333 | 79153291 |
JC virus infection | 18.23 | 9.99 | 3 | 573761 | 3878 | 79166746 |
Hypersensitivity vasculitis | 18.15 | 9.99 | 14 | 573750 | 6929 | 79163695 |
Abnormal dreams | 18.13 | 9.99 | 34 | 573730 | 11378 | 79159246 |
Cerebral ischaemia | 18.10 | 9.99 | 33 | 573731 | 11162 | 79159462 |
Human herpesvirus 6 infection | 18.04 | 9.99 | 8 | 573756 | 5362 | 79165262 |
Osteolysis | 18.03 | 9.99 | 5 | 573759 | 4493 | 79166131 |
Febrile bone marrow aplasia | 17.99 | 9.99 | 42 | 573722 | 12978 | 79157646 |
Renal disorder | 17.89 | 9.99 | 205 | 573559 | 41900 | 79128724 |
Dystonia | 17.89 | 9.99 | 86 | 573678 | 21313 | 79149311 |
Blood urine present | 17.88 | 9.99 | 233 | 573531 | 21064 | 79149560 |
Left ventricular dysfunction | 17.87 | 9.99 | 75 | 573689 | 19286 | 79151338 |
Consciousness fluctuating | 17.81 | 9.99 | 42 | 573722 | 1927 | 79168697 |
Liver transplant | 17.80 | 9.99 | 71 | 573693 | 4352 | 79166272 |
Concomitant disease aggravated | 17.77 | 9.99 | 43 | 573721 | 13124 | 79157500 |
Transaminases increased | 17.75 | 9.99 | 493 | 573271 | 51250 | 79119374 |
Osteomyelitis | 17.75 | 9.99 | 151 | 573613 | 32714 | 79137910 |
Arrhythmia | 17.71 | 9.99 | 322 | 573442 | 60950 | 79109674 |
Aplastic anaemia | 17.69 | 9.99 | 202 | 573562 | 17703 | 79152921 |
Complication of device insertion | 17.65 | 9.99 | 12 | 573752 | 6338 | 79164286 |
Type 2 diabetes mellitus | 17.61 | 9.99 | 537 | 573227 | 56585 | 79114039 |
Gastritis erosive | 17.52 | 9.99 | 32 | 573732 | 10815 | 79159809 |
Inappropriate antidiuretic hormone secretion | 17.50 | 9.99 | 114 | 573650 | 26199 | 79144425 |
Generalised tonic-clonic seizure | 17.43 | 9.99 | 217 | 573547 | 43693 | 79126931 |
Laboratory test abnormal | 17.42 | 9.99 | 124 | 573640 | 27924 | 79142700 |
Blood creatine phosphokinase increased | 17.36 | 9.99 | 353 | 573411 | 65737 | 79104887 |
Self-medication | 17.26 | 9.99 | 78 | 573686 | 5054 | 79165570 |
Pain in jaw | 17.24 | 9.99 | 231 | 573533 | 45920 | 79124704 |
Metastases to bone | 17.19 | 9.99 | 104 | 573660 | 24323 | 79146301 |
Ventricular extrasystoles | 17.17 | 9.99 | 78 | 573686 | 19626 | 79150998 |
Ascites | 17.15 | 9.99 | 413 | 573351 | 75149 | 79095475 |
Vaginal haemorrhage | 16.91 | 9.99 | 90 | 573674 | 21727 | 79148897 |
Hemiparesis | 16.89 | 9.99 | 158 | 573606 | 33575 | 79137049 |
Injection site discomfort | 16.88 | 9.99 | 8 | 573756 | 5158 | 79165466 |
Accidental exposure to product | 16.87 | 9.99 | 144 | 573620 | 31178 | 79139446 |
Somnolence | 16.80 | 9.99 | 1965 | 571799 | 237016 | 78933608 |
Nocturia | 16.69 | 9.99 | 47 | 573717 | 13634 | 79156990 |
Granulomatosis with polyangiitis | 16.68 | 9.99 | 52 | 573712 | 2818 | 79167806 |
Staphylococcal infection | 16.64 | 9.99 | 307 | 573457 | 57988 | 79112636 |
Skin burning sensation | 16.64 | 9.99 | 45 | 573719 | 13227 | 79157397 |
Disorientation | 16.58 | 9.99 | 335 | 573429 | 62441 | 79108183 |
Prothrombin time shortened | 16.51 | 9.99 | 56 | 573708 | 3172 | 79167452 |
Dyslipidaemia | 16.50 | 9.99 | 37 | 573727 | 11596 | 79159028 |
Cardiotoxicity | 16.50 | 9.99 | 40 | 573724 | 12199 | 79158425 |
Unevaluable event | 16.41 | 9.99 | 291 | 573473 | 55294 | 79115330 |
Aortic valve incompetence | 16.41 | 9.99 | 27 | 573737 | 9503 | 79161121 |
Retinal haemorrhage | 16.39 | 9.99 | 21 | 573743 | 8196 | 79162428 |
Burning sensation | 16.36 | 9.99 | 310 | 573454 | 58322 | 79112302 |
Post cholecystectomy syndrome | 16.36 | 9.99 | 17 | 573747 | 375 | 79170249 |
Sepsis | 16.31 | 9.99 | 1693 | 572071 | 267735 | 78902889 |
Brain oedema | 16.30 | 9.99 | 264 | 573500 | 24999 | 79145625 |
Hip arthroplasty | 16.27 | 9.99 | 354 | 573410 | 35402 | 79135222 |
Hypoglycaemic coma | 16.14 | 9.99 | 7 | 573757 | 4753 | 79165871 |
Potentiating drug interaction | 16.12 | 9.99 | 24 | 573740 | 8795 | 79161829 |
Cryopyrin associated periodic syndrome | 16.11 | 9.99 | 17 | 573747 | 382 | 79170242 |
Application site pain | 16.06 | 9.99 | 7 | 573757 | 4740 | 79165884 |
Adenocarcinoma of colon | 16.04 | 9.99 | 10 | 573754 | 5531 | 79165093 |
Hyperammonaemia | 15.96 | 9.99 | 35 | 573729 | 11058 | 79159566 |
Pneumonia | 15.96 | 9.99 | 4368 | 569396 | 655878 | 78514746 |
Peripheral venous disease | 15.95 | 9.99 | 180 | 573584 | 15729 | 79154895 |
Agranulocytosis | 15.89 | 9.99 | 228 | 573536 | 44802 | 79125822 |
Chest pain | 15.88 | 9.99 | 1783 | 571981 | 280521 | 78890103 |
Candida infection | 15.87 | 9.99 | 187 | 573577 | 38027 | 79132597 |
Partial seizures | 15.87 | 9.99 | 25 | 573739 | 8953 | 79161671 |
Erysipelas | 15.81 | 9.99 | 34 | 573730 | 10816 | 79159808 |
Pulmonary alveolar haemorrhage | 15.80 | 9.99 | 37 | 573727 | 11420 | 79159204 |
Cells in urine | 15.75 | 9.99 | 13 | 573751 | 211 | 79170413 |
Coagulation factor X level decreased | 15.75 | 9.99 | 10 | 573754 | 105 | 79170519 |
Smear cervix abnormal | 15.72 | 9.99 | 47 | 573717 | 2489 | 79168135 |
Band neutrophil count increased | 15.72 | 9.99 | 22 | 573742 | 668 | 79169956 |
Inflammation | 15.67 | 9.99 | 825 | 572939 | 92928 | 79077696 |
Sulphaemoglobinaemia | 15.66 | 9.99 | 8 | 573756 | 53 | 79170571 |
Pupillary light reflex tests abnormal | 15.61 | 9.99 | 15 | 573749 | 300 | 79170324 |
Antipsychotic drug level increased | 15.59 | 9.99 | 12 | 573752 | 5945 | 79164679 |
Long QT syndrome | 15.58 | 9.99 | 12 | 573752 | 5943 | 79164681 |
Muscle disorder | 15.57 | 9.99 | 11 | 573753 | 5696 | 79164928 |
Post-traumatic stress disorder | 15.54 | 9.99 | 73 | 573691 | 4808 | 79165816 |
Blood creatinine decreased | 15.52 | 9.99 | 103 | 573661 | 7722 | 79162902 |
Haemoglobin decreased | 15.51 | 9.99 | 1381 | 572383 | 220738 | 78949886 |
Immune effector cell-associated neurotoxicity syndrome | 15.46 | 9.99 | 83 | 573681 | 5765 | 79164859 |
Glutathione decreased | 15.42 | 9.99 | 8 | 573756 | 55 | 79170569 |
Dermatitis | 15.41 | 9.99 | 90 | 573674 | 21231 | 79149393 |
Shock haemorrhagic | 15.41 | 9.99 | 83 | 573681 | 19977 | 79150647 |
Nephrogenic systemic fibrosis | 15.38 | 9.99 | 13 | 573751 | 6147 | 79164477 |
Culture urine positive | 15.36 | 9.99 | 68 | 573696 | 4367 | 79166257 |
Skin cancer | 15.33 | 9.99 | 56 | 573708 | 14984 | 79155640 |
Pneumonia streptococcal | 15.28 | 9.99 | 49 | 573715 | 2696 | 79167928 |
Rheumatoid nodule | 15.21 | 9.99 | 69 | 573695 | 17369 | 79153255 |
Complications of transplanted kidney | 15.21 | 9.99 | 14 | 573750 | 6352 | 79164272 |
Dysstasia | 15.20 | 9.99 | 127 | 573637 | 27619 | 79143005 |
Blood immunoglobulin E increased | 15.20 | 9.99 | 12 | 573752 | 5870 | 79164754 |
Acute myeloid leukaemia recurrent | 15.06 | 9.99 | 3 | 573761 | 3380 | 79167244 |
Heavy menstrual bleeding | 15.06 | 9.99 | 51 | 573713 | 13960 | 79156664 |
Anal fissure | 15.04 | 9.99 | 101 | 573663 | 7602 | 79163022 |
Intraocular pressure increased | 15.01 | 9.99 | 27 | 573737 | 9178 | 79161446 |
Hyperglycaemia | 15.00 | 9.99 | 388 | 573376 | 69947 | 79100677 |
Allergy to chemicals | 14.99 | 9.99 | 47 | 573717 | 2555 | 79168069 |
Carpal tunnel syndrome | 14.89 | 9.99 | 81 | 573683 | 19447 | 79151177 |
Serotonin syndrome | 14.89 | 9.99 | 427 | 573337 | 44600 | 79126024 |
Administration site bruise | 14.84 | 9.99 | 12 | 573752 | 189 | 79170435 |
Rheumatoid lung | 14.78 | 9.99 | 6 | 573758 | 4239 | 79166385 |
Metastases to central nervous system | 14.76 | 9.99 | 64 | 573700 | 16311 | 79154313 |
Squamous cell carcinoma | 14.74 | 9.99 | 60 | 573704 | 15562 | 79155062 |
Bacterial test positive | 14.74 | 9.99 | 98 | 573666 | 7351 | 79163273 |
Neutrophil count decreased | 14.73 | 9.99 | 540 | 573224 | 93419 | 79077205 |
Aortic valve stenosis | 14.72 | 9.99 | 10 | 573754 | 5284 | 79165340 |
Galactorrhoea | 14.71 | 9.99 | 4 | 573760 | 3642 | 79166982 |
Device failure | 14.69 | 9.99 | 14 | 573750 | 6247 | 79164377 |
Retinal vein occlusion | 14.68 | 9.99 | 3 | 573761 | 3320 | 79167304 |
Drug eruption | 14.62 | 9.99 | 225 | 573539 | 43710 | 79126914 |
Monocyte percentage increased | 14.54 | 9.99 | 41 | 573723 | 2100 | 79168524 |
Sciatica | 14.51 | 9.99 | 327 | 573437 | 32895 | 79137729 |
Squamous cell carcinoma of skin | 14.47 | 9.99 | 52 | 573712 | 13981 | 79156643 |
Coronary artery stenosis | 14.42 | 9.99 | 44 | 573720 | 12440 | 79158184 |
Eosinophil percentage increased | 14.41 | 9.99 | 33 | 573731 | 1485 | 79169139 |
Necrotic lymphadenopathy | 14.38 | 9.99 | 9 | 573755 | 92 | 79170532 |
Complication of device removal | 14.37 | 9.99 | 5 | 573759 | 3884 | 79166740 |
Asphyxia | 14.30 | 9.99 | 138 | 573626 | 11582 | 79159042 |
Schizophrenia | 14.28 | 9.99 | 172 | 573592 | 15268 | 79155356 |
Insurance issue | 14.24 | 9.99 | 80 | 573684 | 5653 | 79164971 |
Parkinsonism | 14.24 | 9.99 | 66 | 573698 | 16518 | 79154106 |
Dyspnoea at rest | 14.21 | 9.99 | 19 | 573745 | 7283 | 79163341 |
Atypical femur fracture | 14.16 | 9.99 | 10 | 573754 | 5179 | 79165445 |
Brain abscess | 14.16 | 9.99 | 9 | 573755 | 4927 | 79165697 |
Administration site swelling | 14.16 | 9.99 | 18 | 573746 | 497 | 79170127 |
Reversible airways obstruction | 14.13 | 9.99 | 41 | 573723 | 2135 | 79168489 |
Polydipsia | 14.11 | 9.99 | 16 | 573748 | 6589 | 79164035 |
High density lipoprotein decreased | 14.04 | 9.99 | 8 | 573756 | 4647 | 79165977 |
Dislocation of vertebra | 14.02 | 9.99 | 101 | 573663 | 7779 | 79162845 |
Application site pruritus | 13.91 | 9.99 | 5 | 573759 | 3805 | 79166819 |
Monoparesis | 13.89 | 9.99 | 4 | 573760 | 3507 | 79167117 |
Klebsiella infection | 13.83 | 9.99 | 62 | 573702 | 15658 | 79154966 |
Infusion site irritation | 13.82 | 9.99 | 22 | 573742 | 751 | 79169873 |
Acute generalised exanthematous pustulosis | 13.76 | 9.99 | 187 | 573577 | 17067 | 79153557 |
Syringe issue | 13.73 | 9.99 | 15 | 573749 | 6283 | 79164341 |
Infective pulmonary exacerbation of cystic fibrosis | 13.66 | 9.99 | 47 | 573717 | 12804 | 79157820 |
Vein collapse | 13.57 | 9.99 | 27 | 573737 | 1101 | 79169523 |
Encephalopathy | 13.56 | 9.99 | 604 | 573160 | 66793 | 79103831 |
Femur fracture | 13.53 | 9.99 | 196 | 573568 | 38456 | 79132168 |
Cystitis | 13.50 | 9.99 | 485 | 573279 | 52247 | 79118377 |
Hepatocellular injury | 13.47 | 9.99 | 251 | 573513 | 47342 | 79123282 |
Infusion site urticaria | 13.47 | 9.99 | 27 | 573737 | 1107 | 79169517 |
Delusion of grandeur | 13.45 | 9.99 | 31 | 573733 | 1401 | 79169223 |
Ankylosing spondylitis | 13.41 | 9.99 | 44 | 573720 | 12161 | 79158463 |
Paresis | 13.32 | 9.99 | 7 | 573757 | 4254 | 79166370 |
Abnormal loss of weight | 13.27 | 9.99 | 25 | 573739 | 8351 | 79162273 |
Intestinal haemorrhage | 13.26 | 9.99 | 16 | 573748 | 6410 | 79164214 |
Cytomegalovirus chorioretinitis | 13.20 | 9.99 | 12 | 573752 | 5478 | 79165146 |
Anti-erythrocyte antibody positive | 13.18 | 9.99 | 8 | 573756 | 77 | 79170547 |
Suspected COVID-19 | 13.18 | 9.99 | 51 | 573713 | 3082 | 79167542 |
Limb discomfort | 13.17 | 9.99 | 162 | 573602 | 32688 | 79137936 |
Left ventricular failure | 13.16 | 9.99 | 31 | 573733 | 9550 | 79161074 |
Large intestine polyp | 13.16 | 9.99 | 47 | 573717 | 12661 | 79157963 |
Leukoencephalopathy | 13.16 | 9.99 | 23 | 573741 | 7906 | 79162718 |
Blood immunoglobulin A decreased | 13.15 | 9.99 | 31 | 573733 | 1422 | 79169202 |
Pleural effusion | 13.14 | 9.99 | 884 | 572880 | 144378 | 79026246 |
Pneumatosis intestinalis | 13.12 | 9.99 | 16 | 573748 | 6381 | 79164243 |
Blood loss anaemia | 13.12 | 9.99 | 62 | 573702 | 15436 | 79155188 |
Blood glucose abnormal | 13.11 | 9.99 | 36 | 573728 | 10530 | 79160094 |
Palpitations | 13.10 | 9.99 | 761 | 573003 | 125849 | 79044775 |
Mycobacterial infection | 13.07 | 9.99 | 5 | 573759 | 3663 | 79166961 |
Postmortem blood drug level increased | 13.07 | 9.99 | 22 | 573742 | 787 | 79169837 |
Ischaemic cardiomyopathy | 13.06 | 9.99 | 22 | 573742 | 7673 | 79162951 |
Pre-eclampsia | 13.03 | 9.99 | 19 | 573745 | 7022 | 79163602 |
Diffuse large B-cell lymphoma recurrent | 13.02 | 9.99 | 7 | 573757 | 4200 | 79166424 |
Post procedural pulmonary embolism | 12.98 | 9.99 | 13 | 573751 | 274 | 79170350 |
Peripheral sensory neuropathy | 12.97 | 9.99 | 49 | 573715 | 12984 | 79157640 |
Infusion site rash | 12.97 | 9.99 | 34 | 573730 | 1668 | 79168956 |
Tooth injury | 12.96 | 9.99 | 38 | 573726 | 1990 | 79168634 |
Plasma cell myeloma | 12.96 | 9.99 | 288 | 573476 | 52971 | 79117653 |
Electrocardiogram QRS complex prolonged | 12.95 | 9.99 | 127 | 573637 | 10706 | 79159918 |
Vital functions abnormal | 12.91 | 9.99 | 22 | 573742 | 795 | 79169829 |
Haemoglobin urine present | 12.89 | 9.99 | 24 | 573740 | 931 | 79169693 |
Pulmonary tuberculosis | 12.88 | 9.99 | 23 | 573741 | 7842 | 79162782 |
Upper respiratory tract infection | 12.86 | 9.99 | 790 | 572974 | 90378 | 79080246 |
Dysgeusia | 12.84 | 9.99 | 313 | 573451 | 56864 | 79113760 |
Therapy non-responder | 12.83 | 9.99 | 538 | 573226 | 91767 | 79078857 |
Aminoaciduria | 12.83 | 9.99 | 15 | 573749 | 379 | 79170245 |
Accidental death | 12.81 | 9.99 | 63 | 573701 | 4228 | 79166396 |
Gastrooesophageal reflux disease | 12.78 | 9.99 | 616 | 573148 | 103630 | 79066994 |
Peripheral arterial occlusive disease | 12.78 | 9.99 | 25 | 573739 | 8233 | 79162391 |
Sleep disorder due to a general medical condition | 12.75 | 9.99 | 56 | 573708 | 14221 | 79156403 |
Upper gastrointestinal haemorrhage | 12.74 | 9.99 | 215 | 573549 | 41165 | 79129459 |
Granulocytopenia | 12.71 | 9.99 | 41 | 573723 | 11390 | 79159234 |
Ductus arteriosus stenosis foetal | 12.68 | 9.99 | 8 | 573756 | 83 | 79170541 |
Physical disability | 12.61 | 9.99 | 4 | 573760 | 3294 | 79167330 |
Rash papular | 12.61 | 9.99 | 99 | 573665 | 21817 | 79148807 |
Catheter site bruise | 12.58 | 9.99 | 16 | 573748 | 442 | 79170182 |
Mean cell haemoglobin concentration increased | 12.57 | 9.99 | 23 | 573741 | 880 | 79169744 |
Serum sickness | 12.54 | 9.99 | 56 | 573708 | 3610 | 79167014 |
Left ventricular hypertrophy | 12.54 | 9.99 | 40 | 573724 | 11151 | 79159473 |
Oedema | 12.51 | 9.99 | 718 | 573046 | 118862 | 79051762 |
Subarachnoid haemorrhage | 12.50 | 9.99 | 114 | 573650 | 24351 | 79146273 |
Eye infection | 12.47 | 9.99 | 136 | 573628 | 11784 | 79158840 |
Hernia | 12.44 | 9.99 | 182 | 573582 | 16877 | 79153747 |
Injection site extravasation | 12.37 | 9.99 | 115 | 573649 | 9554 | 79161070 |
Personality change | 12.36 | 9.99 | 35 | 573729 | 10135 | 79160489 |
Precancerous cells present | 12.31 | 9.99 | 27 | 573737 | 1180 | 79169444 |
B-cell lymphoma | 12.27 | 9.99 | 16 | 573748 | 6199 | 79164425 |
Abdominal pain lower | 12.27 | 9.99 | 158 | 573606 | 31624 | 79139000 |
Dysuria | 12.26 | 9.99 | 276 | 573488 | 50675 | 79119949 |
Endophthalmitis | 12.24 | 9.99 | 17 | 573747 | 6411 | 79164213 |
Hepatitis B | 12.23 | 9.99 | 26 | 573738 | 8306 | 79162318 |
Secondary immunodeficiency | 12.23 | 9.99 | 4 | 573760 | 3230 | 79167394 |
Ejection fraction decreased | 12.22 | 9.99 | 175 | 573589 | 34402 | 79136222 |
Cyanosis neonatal | 12.21 | 9.99 | 7 | 573757 | 60 | 79170564 |
Focal dyscognitive seizures | 12.17 | 9.99 | 5 | 573759 | 3507 | 79167117 |
Myocardial ischaemia | 12.15 | 9.99 | 121 | 573643 | 25398 | 79145226 |
Injection site nodule | 12.13 | 9.99 | 6 | 573758 | 3774 | 79166850 |
Postoperative delirium | 12.12 | 9.99 | 14 | 573750 | 349 | 79170275 |
Oxygen saturation abnormal | 12.09 | 9.99 | 65 | 573699 | 4517 | 79166107 |
Granuloma | 12.09 | 9.99 | 26 | 573738 | 8271 | 79162353 |
Glucose tolerance impaired | 12.06 | 9.99 | 25 | 573739 | 8059 | 79162565 |
Rhinalgia | 12.05 | 9.99 | 41 | 573723 | 2326 | 79168298 |
Bone erosion | 12.03 | 9.99 | 77 | 573687 | 17770 | 79152854 |
Stress | 12.01 | 9.99 | 694 | 573070 | 78918 | 79091706 |
Dependent personality disorder | 12.01 | 9.99 | 9 | 573755 | 126 | 79170498 |
Atrioventricular block | 11.99 | 9.99 | 56 | 573708 | 13985 | 79156639 |
Mucormycosis | 11.96 | 9.99 | 27 | 573737 | 8442 | 79162182 |
Psychomotor skills impaired | 11.95 | 9.99 | 12 | 573752 | 5225 | 79165399 |
Bone lesion | 11.94 | 9.99 | 15 | 573749 | 5904 | 79164720 |
Breast cancer | 11.93 | 9.99 | 171 | 573593 | 33610 | 79137014 |
Caesarean section | 11.92 | 9.99 | 48 | 573716 | 12487 | 79158137 |
Total lung capacity increased | 11.87 | 9.99 | 40 | 573724 | 2258 | 79168366 |
Small fibre neuropathy | 11.83 | 9.99 | 17 | 573747 | 529 | 79170095 |
Therapy change | 11.80 | 9.99 | 22 | 573742 | 7377 | 79163247 |
Fanconi syndrome | 11.78 | 9.99 | 3 | 573761 | 2853 | 79167771 |
Intermenstrual bleeding | 11.77 | 9.99 | 15 | 573749 | 5869 | 79164755 |
Transfusion-related circulatory overload | 11.75 | 9.99 | 14 | 573750 | 361 | 79170263 |
Tachyarrhythmia | 11.73 | 9.99 | 20 | 573744 | 6942 | 79163682 |
Aggression | 11.71 | 9.99 | 278 | 573486 | 50680 | 79119944 |
Congestive hepatopathy | 11.66 | 9.99 | 64 | 573700 | 4483 | 79166141 |
Urobilinogen urine increased | 11.61 | 9.99 | 19 | 573745 | 664 | 79169960 |
Arteriospasm coronary | 11.59 | 9.99 | 19 | 573745 | 6697 | 79163927 |
Peritonitis bacterial | 11.57 | 9.99 | 33 | 573731 | 9534 | 79161090 |
Alpha 1 microglobulin increased | 11.57 | 9.99 | 7 | 573757 | 67 | 79170557 |
Product use issue | 11.55 | 9.99 | 1700 | 572064 | 208122 | 78962502 |
Bezoar | 11.51 | 9.99 | 44 | 573720 | 2644 | 79167980 |
Anticholinergic syndrome | 11.49 | 9.99 | 54 | 573710 | 3557 | 79167067 |
Movement disorder | 11.47 | 9.99 | 133 | 573631 | 27126 | 79143498 |
Maple syrup disease | 11.43 | 9.99 | 4 | 573760 | 8 | 79170616 |
Urethral obstruction | 11.43 | 9.99 | 12 | 573752 | 268 | 79170356 |
C-reactive protein | 11.41 | 9.99 | 68 | 573696 | 4911 | 79165713 |
Delusion | 11.40 | 9.99 | 93 | 573671 | 20330 | 79150294 |
Product preparation error | 11.35 | 9.99 | 15 | 573749 | 5778 | 79164846 |
Allergy test negative | 11.35 | 9.99 | 13 | 573751 | 321 | 79170303 |
Mood swings | 11.34 | 9.99 | 90 | 573674 | 19790 | 79150834 |
Toxic skin eruption | 11.34 | 9.99 | 104 | 573660 | 22189 | 79148435 |
Monocyte count increased | 11.32 | 9.99 | 122 | 573642 | 10539 | 79160085 |
Premature delivery | 11.29 | 9.99 | 111 | 573653 | 23356 | 79147268 |
Diabetic neuropathy | 11.28 | 9.99 | 17 | 573747 | 6199 | 79164425 |
Product dispensing error | 11.26 | 9.99 | 53 | 573711 | 13210 | 79157414 |
Pneumonia viral | 11.26 | 9.99 | 108 | 573656 | 9050 | 79161574 |
Severe invasive streptococcal infection | 11.24 | 9.99 | 6 | 573758 | 44 | 79170580 |
Head injury | 11.24 | 9.99 | 195 | 573569 | 37174 | 79133450 |
Ventricular hypokinesia | 11.23 | 9.99 | 32 | 573732 | 9247 | 79161377 |
Hypoacusis | 11.23 | 9.99 | 151 | 573613 | 29999 | 79140625 |
Haematemesis | 11.23 | 9.99 | 288 | 573476 | 51976 | 79118648 |
Angiokeratoma | 11.21 | 9.99 | 11 | 573753 | 226 | 79170398 |
Deafness | 11.20 | 9.99 | 97 | 573667 | 20940 | 79149684 |
Total lung capacity decreased | 11.19 | 9.99 | 46 | 573718 | 2859 | 79167765 |
Diastolic dysfunction | 11.18 | 9.99 | 40 | 573724 | 10771 | 79159853 |
Mixed liver injury | 11.18 | 9.99 | 93 | 573671 | 7485 | 79163139 |
Acidosis hyperchloraemic | 11.16 | 9.99 | 21 | 573743 | 821 | 79169803 |
Skin mass | 11.15 | 9.99 | 26 | 573738 | 8037 | 79162587 |
Blood uric acid decreased | 11.14 | 9.99 | 27 | 573737 | 1261 | 79169363 |
Diabetic metabolic decompensation | 11.14 | 9.99 | 5 | 573759 | 3327 | 79167297 |
Pollakiuria | 11.13 | 9.99 | 195 | 573569 | 37122 | 79133502 |
Nasal necrosis | 11.12 | 9.99 | 9 | 573755 | 142 | 79170482 |
Embedded device | 11.06 | 9.99 | 5 | 573759 | 3314 | 79167310 |
Malaise | 11.05 | 9.99 | 3250 | 570514 | 486619 | 78684005 |
Complication associated with device | 11.04 | 9.99 | 77 | 573687 | 17419 | 79153205 |
Irritability | 11.03 | 9.99 | 219 | 573545 | 40925 | 79129699 |
Urinary casts | 11.03 | 9.99 | 26 | 573738 | 1193 | 79169431 |
Sensitisation | 11.02 | 9.99 | 5 | 573759 | 3306 | 79167318 |
Nerve block | 11.01 | 9.99 | 19 | 573745 | 694 | 79169930 |
Decerebrate posture | 11.00 | 9.99 | 10 | 573754 | 186 | 79170438 |
Aspartate aminotransferase | 10.98 | 9.99 | 17 | 573747 | 566 | 79170058 |
Osteogenesis imperfecta | 10.97 | 9.99 | 16 | 573748 | 505 | 79170119 |
Leukocytosis | 10.96 | 9.99 | 399 | 573365 | 43056 | 79127568 |
Leukaemia | 10.95 | 9.99 | 16 | 573748 | 5909 | 79164715 |
Haemorrhage intracranial | 10.95 | 9.99 | 128 | 573636 | 26065 | 79144559 |
Epilepsy with myoclonic-atonic seizures | 10.92 | 9.99 | 8 | 573756 | 108 | 79170516 |
Coronary artery occlusion | 10.88 | 9.99 | 65 | 573699 | 15250 | 79155374 |
Cardiac operation | 10.86 | 9.99 | 12 | 573752 | 5000 | 79165624 |
Oral discomfort | 10.85 | 9.99 | 35 | 573729 | 9725 | 79160899 |
Vertigo | 10.83 | 9.99 | 397 | 573367 | 68685 | 79101939 |
Specific gravity urine increased | 10.83 | 9.99 | 15 | 573749 | 451 | 79170173 |
Plasma cell myeloma recurrent | 10.81 | 9.99 | 12 | 573752 | 4989 | 79165635 |
Urine oxalate increased | 10.76 | 9.99 | 11 | 573753 | 238 | 79170386 |
Epstein-Barr virus associated lymphoproliferative disorder | 10.75 | 9.99 | 6 | 573758 | 3526 | 79167098 |
Mania | 10.73 | 9.99 | 82 | 573682 | 18178 | 79152446 |
Uterine perforation | 10.72 | 9.99 | 18 | 573746 | 6285 | 79164339 |
Polycystic ovaries | 10.69 | 9.99 | 7 | 573757 | 3772 | 79166852 |
Eyelid ptosis | 10.68 | 9.99 | 42 | 573722 | 11002 | 79159622 |
Orbital compartment syndrome | 10.68 | 9.99 | 7 | 573757 | 78 | 79170546 |
Leukocyturia | 10.68 | 9.99 | 35 | 573729 | 1948 | 79168676 |
Vaccination site pain | 10.66 | 9.99 | 10 | 573754 | 194 | 79170430 |
PCO2 decreased | 10.65 | 9.99 | 48 | 573716 | 3106 | 79167518 |
Proteinuria | 10.63 | 9.99 | 167 | 573597 | 32335 | 79138289 |
Blindness | 10.62 | 9.99 | 142 | 573622 | 28241 | 79142383 |
Lupus vulgaris | 10.62 | 9.99 | 50 | 573714 | 3296 | 79167328 |
Fibrin D dimer increased | 10.61 | 9.99 | 102 | 573662 | 8552 | 79162072 |
Febrile neutropenia | 10.60 | 9.99 | 1853 | 571911 | 229146 | 78941478 |
Pericardial haemorrhage | 10.60 | 9.99 | 10 | 573754 | 4485 | 79166139 |
Cytomegalovirus infection reactivation | 10.59 | 9.99 | 30 | 573734 | 8686 | 79161938 |
Faecaloma | 10.55 | 9.99 | 45 | 573719 | 11519 | 79159105 |
Acute respiratory failure | 10.54 | 9.99 | 337 | 573427 | 59204 | 79111420 |
Metastasis | 10.50 | 9.99 | 21 | 573743 | 6859 | 79163765 |
Device deployment issue | 10.46 | 9.99 | 5 | 573759 | 3207 | 79167417 |
Thyroid cancer | 10.42 | 9.99 | 15 | 573749 | 5573 | 79165051 |
Chronic gastrointestinal bleeding | 10.41 | 9.99 | 15 | 573749 | 468 | 79170156 |
Hydroxyprolinuria | 10.41 | 9.99 | 6 | 573758 | 52 | 79170572 |
Temperature regulation disorder | 10.40 | 9.99 | 75 | 573689 | 5778 | 79164846 |
Inhibitory drug interaction | 10.40 | 9.99 | 10 | 573754 | 4443 | 79166181 |
Beta haemolytic streptococcal infection | 10.40 | 9.99 | 36 | 573728 | 2061 | 79168563 |
Cytomegalovirus colitis | 10.39 | 9.99 | 11 | 573753 | 4674 | 79165950 |
Diffuse axonal injury | 10.38 | 9.99 | 8 | 573756 | 117 | 79170507 |
Base excess | 10.38 | 9.99 | 7 | 573757 | 82 | 79170542 |
Pemphigoid | 10.36 | 9.99 | 66 | 573698 | 15249 | 79155375 |
Thirst | 10.30 | 9.99 | 85 | 573679 | 18534 | 79152090 |
End stage renal disease | 10.28 | 9.99 | 49 | 573715 | 12171 | 79158453 |
Terminal state | 10.27 | 9.99 | 12 | 573752 | 4877 | 79165747 |
Band neutrophil percentage increased | 10.25 | 9.99 | 14 | 573750 | 415 | 79170209 |
Exposure via inhalation | 10.22 | 9.99 | 8 | 573756 | 120 | 79170504 |
Pharyngitis streptococcal | 10.20 | 9.99 | 120 | 573644 | 10594 | 79160030 |
Transplant failure | 10.18 | 9.99 | 11 | 573753 | 4630 | 79165994 |
Eye haemorrhage | 10.16 | 9.99 | 36 | 573728 | 9721 | 79160903 |
Immunoglobulin G4 related disease | 10.15 | 9.99 | 11 | 573753 | 255 | 79170369 |
Allergy to plants | 10.15 | 9.99 | 19 | 573745 | 740 | 79169884 |
Eczema | 10.14 | 9.99 | 220 | 573544 | 40598 | 79130026 |
Granulocyte count increased | 10.13 | 9.99 | 26 | 573738 | 1259 | 79169365 |
Anger | 10.12 | 9.99 | 77 | 573687 | 17085 | 79153539 |
Dysphagia | 10.11 | 9.99 | 749 | 573015 | 121387 | 79049237 |
Catheter management | 10.08 | 9.99 | 7 | 573757 | 3656 | 79166968 |
Petit mal epilepsy | 10.07 | 9.99 | 16 | 573748 | 5711 | 79164913 |
Splenomegaly | 10.05 | 9.99 | 98 | 573666 | 20656 | 79149968 |
Testicular infarction | 10.04 | 9.99 | 6 | 573758 | 56 | 79170568 |
Pregnancy with contraceptive device | 10.03 | 9.99 | 7 | 573757 | 3647 | 79166977 |
Chills | 10.02 | 9.99 | 1308 | 572456 | 158926 | 79011698 |
Obsessive-compulsive disorder | 10.01 | 9.99 | 17 | 573747 | 5910 | 79164714 |
None
Source | Code | Description |
---|---|---|
ATC | N07XX59 | NERVOUS SYSTEM OTHER NERVOUS SYSTEM DRUGS OTHER NERVOUS SYSTEM DRUGS Other nervous system drugs |
ATC | R05DA09 | RESPIRATORY SYSTEM COUGH AND COLD PREPARATIONS COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS Opium alkaloids and derivatives |
CHEBI has role | CHEBI:35703 | Xenobiotic |
CHEBI has role | CHEBI:50266 | Prodrugs |
CHEBI has role | CHEBI:50910 | agente neurotoxico |
CHEBI has role | CHEBI:51177 | anti-tussive |
CHEBI has role | CHEBI:60643 | N-methyl-D-aspartate receptor antagonists |
CHEBI has role | CHEBI:78298 | environmental contaminants |
CHEBI has role | CHEBI:146270 | oneirogens |
MeSH PA | D000996 | Antitussive Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D018691 | Excitatory Amino Acid Antagonists |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D019141 | Respiratory System Agents |
FDA MoA | N0000181819 | Uncompetitive NMDA Receptor Antagonists |
FDA EPC | N0000181821 | Uncompetitive N-methyl-D-aspartate Receptor Antagonist |
FDA MoA | N0000182147 | Sigma-1 Receptor Agonists |
FDA EPC | N0000182149 | Sigma-1 Agonist |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Vasomotor rhinitis | indication | 8229003 | DOID:4730 |
Cough | indication | 49727002 | |
Allergic rhinitis | indication | 61582004 | |
Nasal discharge | indication | 64531003 | |
Nasal congestion | indication | 68235000 | |
Rhinitis | indication | 70076002 | DOID:4483 |
Sneezing | indication | 76067001 | |
Common cold | indication | 82272006 | DOID:10459 |
Headache disorder | indication | 230461009 | |
Sore throat symptom | indication | 267102003 | |
Influenza-like symptoms | indication | 315642008 | |
Major depressive disorder | indication | 370143000 | |
Fever | indication | 386661006 | |
Pseudobulbar affect | indication | 432776007 | |
Mouth Irritation | indication | ||
Opioid withdrawal | off-label use | 87132004 | |
Neurotoxicity caused by methotrexate | off-label use | 129666005 | |
Metabolic alkalosis | contraindication | 1388004 | |
Brain damage | contraindication | 2470005 | |
Anuria | contraindication | 2472002 | DOID:2983 |
Goiter | contraindication | 3716002 | DOID:12176 |
Ocular hypertension | contraindication | 4210003 | DOID:9282 |
Hypocalcemia | contraindication | 5291005 | |
Tachyarrhythmia | contraindication | 6285003 | |
Suicidal thoughts | contraindication | 6471006 | |
Dependent drug abuse | contraindication | 6525002 | |
Urinary tract obstruction | contraindication | 7163005 | DOID:5200 |
Alcoholism | contraindication | 7200002 | |
Alcohol withdrawal delirium | contraindication | 8635005 | |
Peptic ulcer | contraindication | 13200003 | DOID:750 |
Chronic obstructive lung disease | contraindication | 13645005 | DOID:3083 |
Asthenia | contraindication | 13791008 | |
Hyperkalemia | contraindication | 14140009 | |
Severe chronic ulcerative colitis | contraindication | 14311001 | |
Constipation | contraindication | 14760008 | DOID:2089 |
Hyperbilirubinemia | contraindication | 14783006 | DOID:2741 |
Neuroleptic malignant syndrome | contraindication | 15244003 | DOID:14464 |
Mood swings | contraindication | 18963009 | |
Pulmonary edema | contraindication | 19242006 | DOID:11396 |
Lowered convulsive threshold | contraindication | 19260006 | |
Hashimoto thyroiditis | contraindication | 21983002 | |
Myocardial infarction | contraindication | 22298006 | DOID:5844 |
Disorder of the central nervous system | contraindication | 23853001 | DOID:331 |
Inflammatory bowel disease | contraindication | 24526004 | DOID:0050589 |
Ventricular tachycardia | contraindication | 25569003 | |
Acute tuberculosis | contraindication | 25629007 | |
Alcohol intoxication | contraindication | 25702006 | |
Complete atrioventricular block | contraindication | 27885002 | |
Shock | contraindication | 27942005 | |
Toxic megacolon | contraindication | 28536002 | DOID:1770 |
Atony of colon | contraindication | 29479008 | |
Hypercapnia | contraindication | 29596007 | |
Torsades de pointes | contraindication | 31722008 | |
Bronchitis | contraindication | 32398004 | DOID:6132 |
Dehydration | contraindication | 34095006 | |
Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
Acute hepatitis | contraindication | 37871000 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Methemoglobinemia | contraindication | 38959009 | DOID:10783 |
Hypernatremia | contraindication | 39355002 | |
Disorder of gallbladder | contraindication | 39621005 | DOID:0060262 |
Hypothyroidism | contraindication | 40930008 | DOID:1459 |
Complete trisomy 21 syndrome | contraindication | 41040004 | DOID:14250 |
Hypokalemia | contraindication | 43339004 | |
Conduction disorder of the heart | contraindication | 44808001 | |
Low blood pressure | contraindication | 45007003 | |
Achalasia of esophagus | contraindication | 45564002 | DOID:9164 |
Chronic heart failure | contraindication | 48447003 | |
Bradycardia | contraindication | 48867003 | |
Disorder of cardiovascular system | contraindication | 49601007 | DOID:1287 |
Acidosis | contraindication | 51387008 | |
Coronary arteriosclerosis | contraindication | 53741008 | DOID:3393 |
Paralytic ileus | contraindication | 55525008 | DOID:8442 |
Left ventricular hypertrophy | contraindication | 55827005 | |
Peptic reflux disease | contraindication | 57643001 | |
Acute nephropathy | contraindication | 58574008 | |
Metabolic acidosis | contraindication | 59455009 | |
Hepatic failure | contraindication | 59927004 | |
Ulcerative colitis | contraindication | 64766004 | DOID:8577 |
Arterial thrombosis | contraindication | 65198009 | |
Drug AND/OR toxin-induced diarrhea | contraindication | 65979008 | |
Substance abuse | contraindication | 66214007 | |
Benign intracranial hypertension | contraindication | 68267002 | DOID:11459 |
Poisoning by acetaminophen | contraindication | 70273001 | |
Arteriosclerotic vascular disease | contraindication | 72092001 | |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Sleep apnea | contraindication | 73430006 | DOID:0050847 |
Urethral stricture | contraindication | 76618002 | |
Spastic paralysis | contraindication | 78403003 | |
Disturbance of salivary secretion | contraindication | 78948009 | |
Decreased respiratory function | contraindication | 80954004 | |
Disorder of brain | contraindication | 81308009 | DOID:936 |
Injury of head | contraindication | 82271004 | |
Chronic idiopathic constipation | contraindication | 82934008 | |
Oliguria | contraindication | 83128009 | |
Cor pulmonale | contraindication | 83291003 | DOID:8515 |
Hiatal hernia | contraindication | 84089009 | DOID:12642 |
Epilepsy | contraindication | 84757009 | DOID:1826 |
Left heart failure | contraindication | 85232009 | |
Pulmonary emphysema | contraindication | 87433001 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Myasthenia gravis | contraindication | 91637004 | DOID:437 |
Dermatitis herpetiformis | contraindication | 111196000 | DOID:8505 |
Anemia due to enzyme deficiency | contraindication | 111577008 | |
Prolonged QT interval | contraindication | 111975006 | |
Acute abdominal pain | contraindication | 116290004 | |
Deficiency of glucose-6-phosphate dehydrogenase | contraindication | 124134002 | DOID:2862 |
Deficiency of cytochrome-b>5< reductase | contraindication | 124184009 | |
Gastrointestinal obstruction | contraindication | 126765001 | |
Neoplasm of brain | contraindication | 126952004 | DOID:1319 |
Seizure disorder | contraindication | 128613002 | |
Autonomic dysreflexia | contraindication | 129618003 | |
Bleeding | contraindication | 131148009 | |
Hypomagnesemia | contraindication | 190855004 | |
Drug-induced psychosis | contraindication | 191483003 | DOID:1742 |
Partial atrioventricular block | contraindication | 195039008 | |
Acute pancreatitis | contraindication | 197456007 | DOID:2913 |
Impaired renal function disorder | contraindication | 197663003 | |
Myocardial dysfunction | contraindication | 233928007 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Hyporeninemic hypoaldosteronism | contraindication | 236464008 | |
Bladder outflow obstruction | contraindication | 236645006 | |
Morbid obesity | contraindication | 238136002 | DOID:11981 |
Hypocomplementemic urticarial vasculitis | contraindication | 239945009 | |
Rhabdomyolysis | contraindication | 240131006 | |
Pyloric obstruction | contraindication | 244815007 | |
Benign prostatic hyperplasia | contraindication | 266569009 | |
Retention of urine | contraindication | 267064002 | |
Drowsy | contraindication | 271782001 | |
Peripheral edema | contraindication | 271809000 | |
Exacerbation of asthma | contraindication | 281239006 | |
Pregnancy, function | contraindication | 289908002 | |
Lesion of brain | contraindication | 301766008 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Familial hyperkalemic periodic paralysis | contraindication | 304737009 | DOID:14451 |
Bone marrow depression | contraindication | 307762000 | |
Coma | contraindication | 371632003 | |
Primary adrenocortical insufficiency | contraindication | 373662000 | |
Adrenal cortical hypofunction | contraindication | 386584007 | DOID:10493 |
Operation on gastrointestinal tract | contraindication | 386621005 | |
Hypoxia | contraindication | 389086002 | |
Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
Gastric ulcer | contraindication | 397825006 | DOID:10808 |
Breastfeeding (mother) | contraindication | 413712001 | |
Chronic lung disease | contraindication | 413839001 | |
Disorder of coronary artery | contraindication | 414024009 | |
Traumatic injury | contraindication | 417746004 | |
Central nervous system depression | contraindication | 418072004 | |
Dysfunction of sphincter of Oddi | contraindication | 430887001 | |
Congenital long QT syndrome | contraindication | 442917000 | |
Hypertensive urgency | contraindication | 443482000 | |
Azotemia | contraindication | 445009001 | |
Severe dehydration | contraindication | 450316000 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 9.55 | Basic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
20MG;10MG | NUEDEXTA | AVANIR PHARMS | N021879 | Oct. 29, 2010 | RX | CAPSULE | ORAL | 8227484 | July 17, 2023 | TREATMENT OF PSEUDOBULBAR AFFECT |
20MG;10MG | NUEDEXTA | AVANIR PHARMS | N021879 | Oct. 29, 2010 | RX | CAPSULE | ORAL | 7659282 | Aug. 13, 2026 | TREATMENT OF PSEUDOBULBAR AFFECT |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 8569328 | Oct. 29, 2033 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10058518 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10064857 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10080727 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10092560 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10092561 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10105327 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10105361 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10251879 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10463634 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10512643 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10548857 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10596167 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10772850 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10786469 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10786496 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10799497 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10806710 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10864209 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10874663 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10874664 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10874665 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10881624 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10881657 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10894046 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10894047 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10898453 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10933034 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10945973 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10966941 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10966974 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11020389 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11058648 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11090300 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11096937 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11123343 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11129826 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11141388 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11141416 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11147808 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11185515 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11191739 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11197839 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11207281 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11213521 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11229640 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11234946 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11253491 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11253492 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11273133 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11273134 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11285118 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11285146 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11291638 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11291665 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11298351 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11298352 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11311534 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11344544 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11357744 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11364233 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11382874 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11419867 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11426370 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11426401 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11433067 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11439636 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11478468 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11497721 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11510918 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11517542 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11517543 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11524007 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11524008 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11534414 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11541021 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11541048 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11596627 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11617728 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 11617747 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO INCREASE DEXTROMETHORPHAN PLASMA LEVELS |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9168234 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9198905 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9205083 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9238032 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9278095 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9314462 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9370513 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9375429 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9408815 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9421176 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9457023 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9457025 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9474731 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9486450 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9700528 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9700553 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9707191 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9763932 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9861595 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9867819 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 9968568 | Nov. 5, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10780066 | Nov. 9, 2034 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10780064 | Jan. 7, 2040 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10925842 | Jan. 7, 2040 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10940124 | Jan. 7, 2040 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | 10966942 | Jan. 7, 2040 | DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
---|---|---|---|---|---|---|---|---|---|
105MG;45MG | AUVELITY | AXSOME | N215430 | Aug. 18, 2022 | RX | TABLET, EXTENDED RELEASE | ORAL | Aug. 18, 2025 | NEW PRODUCT |
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 | Membrane receptor | AGONIST | D2 | 6.46 | WOMBAT-PK | ||||
Sodium-dependent serotonin transporter | Transporter | Ki | 8.84 | DRUG MATRIX | |||||
Cytochrome P450 2D6 | Enzyme | Ks | 4.48 | WOMBAT-PK | |||||
Glutamate receptor ionotropic, NMDA 3A | Ion channel | ANTAGONIST | IC50 | 5.70 | WOMBAT-PK | ||||
Glutamate receptor ionotropic, NMDA 2C | Ion channel | BLOCKER | IC50 | 6.33 | IUPHAR | ||||
Solute carrier family 22 member 1 | Transporter | IC50 | 4.98 | CHEMBL | |||||
Taste receptor type 2 member 46 | GPCR | EC50 | 4.51 | CHEMBL | |||||
Sigma non-opioid intracellular receptor 1 | Membrane receptor | Ki | 5.29 | CHEMBL | |||||
Sigma non-opioid intracellular receptor 1 | Membrane other | IC50 | 7.82 | CHEMBL | |||||
Glutamate NMDA receptor | Ion channel | Ki | 5.65 | CHEMBL | |||||
Sodium channel alpha subunits; brain (Types I, II, III) | Ion channel | IC50 | 5.89 | CHEMBL |
ID | Source |
---|---|
4020116 | VUID |
N0000179729 | NUI |
D00848 | KEGG_DRUG |
18609-21-7 | SECONDARY_CAS_RN |
6700-34-1 | SECONDARY_CAS_RN |
7487-74-3 | SECONDARY_CAS_RN |
102490 | RXNORM |
4018051 | VANDF |
4018052 | VANDF |
4020116 | VANDF |
C0011816 | UMLSCUI |
CHEBI:4470 | CHEBI |
CHEMBL52440 | ChEMBL_ID |
DB00514 | DRUGBANK_ID |
CHEMBL1256818 | ChEMBL_ID |
CHEMBL1201004 | ChEMBL_ID |
D003915 | MESH_DESCRIPTOR_UI |
5360696 | PUBCHEM_CID |
6953 | IUPHAR_LIGAND_ID |
166 | INN_ID |
7355X3ROTS | UNII |
18766 | MMSL |
44093 | MMSL |
4565 | MMSL |
4566 | MMSL |
73044 | MMSL |
d00207 | MMSL |
001653 | NDDF |
004427 | NDDF |
005215 | NDDF |
2016004 | SNOMEDCT_US |
387114001 | SNOMEDCT_US |
387237004 | SNOMEDCT_US |
CHEMBL1201461 | ChEMBL_ID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Robitussin Elderberry Maximum Strength Cough plus Chest Congestion DM | HUMAN OTC DRUG LABEL | 2 | 0031-2097 | SOLUTION | 20 mg | ORAL | OTC monograph final | 15 sections |
Childrens Robitussin Elderberry Cough and Chest Congestion DM | HUMAN OTC DRUG LABEL | 2 | 0031-2098 | SOLUTION | 20 mg | ORAL | OTC monograph final | 15 sections |
CHILDRENS DIMETAPP COLD AND COUGH | HUMAN OTC DRUG LABEL | 3 | 0031-2234 | LIQUID | 5 mg | ORAL | OTC monograph final | 16 sections |
Robitussin Tos Seca | HUMAN OTC DRUG LABEL | 1 | 0031-8652 | SYRUP | 10 mg | ORAL | Export only | 1 sections |
Robitussin Tos Seca | HUMAN OTC DRUG LABEL | 1 | 0031-8652 | SYRUP | 10 mg | ORAL | Export only | 1 sections |
Robitussin 12 Hour Cough Relief | HUMAN OTC DRUG LABEL | 1 | 0031-8655 | SUSPENSION, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 15 sections |
Robitussin 12 Hour Cough Relief | HUMAN OTC DRUG LABEL | 1 | 0031-8655 | SUSPENSION, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 15 sections |
Robitussin CF | HUMAN OTC DRUG LABEL | 3 | 0031-8678 | LIQUID | 10 mg | ORAL | Export only | 15 sections |
Robitussin CF | HUMAN OTC DRUG LABEL | 3 | 0031-8678 | LIQUID | 10 mg | ORAL | Export only | 15 sections |
Childrens Robitussin Nighttime Cough Long-Acting DM | HUMAN OTC DRUG LABEL | 2 | 0031-8692 | SOLUTION | 15 mg | ORAL | OTC monograph final | 17 sections |
Childrens Robitussin Nighttime Cough Long-Acting DM | HUMAN OTC DRUG LABEL | 2 | 0031-8692 | SOLUTION | 15 mg | ORAL | OTC monograph final | 17 sections |
Childrens Robitussin Nighttime Cough Long-Acting DM | HUMAN OTC DRUG LABEL | 2 | 0031-8692 | SOLUTION | 15 mg | ORAL | OTC monograph final | 17 sections |
CHILDRENS ROBITUSSIN COUGH AND COLD LONG-ACTING | HUMAN OTC DRUG LABEL | 2 | 0031-8693 | LIQUID | 7.50 mg | ORAL | OTC monograph final | 17 sections |
CHILDRENS ROBITUSSIN COUGH AND COLD LONG-ACTING | HUMAN OTC DRUG LABEL | 2 | 0031-8693 | LIQUID | 15 mg | ORAL | OTC monograph final | 17 sections |
Childrens Robitussin Cough Long-Acting | HUMAN OTC DRUG LABEL | 1 | 0031-8694 | LIQUID | 7.50 mg | ORAL | OTC monograph final | 14 sections |
Childrens Robitussin Cough Long-Acting | HUMAN OTC DRUG LABEL | 1 | 0031-8694 | LIQUID | 7.50 mg | ORAL | OTC monograph final | 14 sections |
Childrens Robitussin Cough and Chest Congestion DM | HUMAN OTC DRUG LABEL | 2 | 0031-8702 | LIQUID | 20 mg | ORAL | OTC MONOGRAPH FINAL | 15 sections |
Childrens Robitussin Cough and Chest Congestion DM | HUMAN OTC DRUG LABEL | 2 | 0031-8702 | LIQUID | 20 mg | ORAL | OTC MONOGRAPH FINAL | 15 sections |
Childrens Robitussin Cough and Chest Congestion DM | HUMAN OTC DRUG LABEL | 2 | 0031-8715 | LIQUID | 5 mg | ORAL | OTC monograph final | 15 sections |
Childrens Robitussin Cough and Chest Congestion DM | HUMAN OTC DRUG LABEL | 2 | 0031-8715 | LIQUID | 5 mg | ORAL | OTC monograph final | 15 sections |
Childrens Robitussin Cough and Cold CF | HUMAN OTC DRUG LABEL | 3 | 0031-8716 | LIQUID | 5 mg | ORAL | OTC monograph final | 17 sections |
Childrens Robitussin Cough and Cold CF | HUMAN OTC DRUG LABEL | 3 | 0031-8716 | LIQUID | 5 mg | ORAL | OTC monograph final | 17 sections |
Childrens Robitussin Cough and Cold CF | HUMAN OTC DRUG LABEL | 3 | 0031-8716 | LIQUID | 5 mg | ORAL | OTC monograph final | 17 sections |
Robitussin Maximum Strength Nighttime Cough DM | HUMAN OTC DRUG LABEL | 2 | 0031-8718 | SOLUTION | 30 mg | ORAL | OTC monograph final | 17 sections |
Robitussin Maximum Strength Nighttime Cough DM | HUMAN OTC DRUG LABEL | 2 | 0031-8718 | SOLUTION | 30 mg | ORAL | OTC monograph final | 17 sections |
Robitussin Maximum Strength Cough Plus Chest Congestion DM | HUMAN OTC DRUG LABEL | 2 | 0031-8719 | CAPSULE, LIQUID FILLED | 10 mg | ORAL | OTC MONOGRAPH FINAL | 15 sections |
Childrens Robitussin 12 Hour Cough Relief | HUMAN OTC DRUG LABEL | 1 | 0031-8725 | SUSPENSION, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 15 sections |
Childrens Robitussin 12 Hour Cough Relief | HUMAN OTC DRUG LABEL | 1 | 0031-8725 | SUSPENSION, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 15 sections |
Childrens Robitussin 12 Hour Cough Relief | HUMAN OTC DRUG LABEL | 1 | 0031-8726 | SUSPENSION, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 15 sections |
Childrens Robitussin 12 Hour Cough Relief | HUMAN OTC DRUG LABEL | 1 | 0031-8726 | SUSPENSION, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 15 sections |