deanol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
787 108-01-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dimethylaminoethanol
  • deanol
  • norcholine
  • dimethylethanolamine
  • bimanol
  • liparon
  • varesal
  • rexolin
An antidepressive agent that has also been used in the treatment of movement disorders. The mechanism of action is not well understood.
  • Molecular weight: 89.14
  • Formula: C4H11NO
  • CLOGP: -0.40
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 23.47
  • ALOGS: 1.20
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N06BX04 NERVOUS SYSTEM
PSYCHOANALEPTICS
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Other psychostimulants and nootropics
MeSH PA D018726 Anti-Dyskinesia Agents
MeSH PA D000928 Antidepressive Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D011619 Psychotropic Drugs
CHEBI has role CHEBI:48578 free radical scavengers
CHEBI has role CHEBI:75358 curing agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.18 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
High affinity choline transporter 1 Transporter Ki 4.25 CHEMBL
Creatine transporter Transporter Ki 4.68 CHEMBL

External reference:

IDSource
2N6K9DRA24 UNII
N0000166807 NUI
D07777 KEGG_DRUG
3116 RXNORM
4036720 VANDF
C0011064 UMLSCUI
CHEBI:271436 CHEBI
CHEMBL122588 ChEMBL_ID
CHEMBL3833347 ChEMBL_ID
7902 PUBCHEM_CID
DB13352 DRUGBANK_ID
CHEMBL1135 ChEMBL_ID
D003642 MESH_DESCRIPTOR_UI
001541 NDDF
7904003 SNOMEDCT_US

Pharmaceutical products:

None