cyclofenil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 753 | 2624-43-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A gonadal stimulant and inducer of ovulation. It is used in the treatment of infertility and amenorrhea, but is thought to be less effective than CLOMIPHENE.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.14 | g | O |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Hosey CM, Chan R, Benet LZ |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | G03GB01 | GENITO URINARY SYSTEM AND SEX HORMONES SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM GONADOTROPINS AND OTHER OVULATION STIMULANTS Ovulation stimulants, synthetic |
| MeSH PA | D005300 | Fertility Agents, Female |
| MeSH PA | D012102 | Reproductive Control Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Estrogen receptor | Nuclear hormone receptor | EC50 | 7.58 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000166610 | NUI |
| D01281 | KEGG_DRUG |
| 2983 | RXNORM |
| C0010560 | UMLSCUI |
| CHEBI:31446 | CHEBI |
| CHEMBL141305 | ChEMBL_ID |
| DB13472 | DRUGBANK_ID |
| D003506 | MESH_DESCRIPTOR_UI |
| 2898 | PUBCHEM_CID |
| 2258 | INN_ID |
| J468V64WZ1 | UNII |
| 003955 | NDDF |
| 325778008 | SNOMEDCT_US |
| 418997003 | SNOMEDCT_US |
Pharmaceutical products:
None