cloxazolam 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diazepam derivatives 721 24166-13-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cloxazolam
  • cloxazolazepam
analog of oxazolam; structure
  • Molecular weight: 349.21
  • Formula: C17H14Cl2N2O2
  • CLOGP: 4.30
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 41.57
  • ALOGS: -4.12
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05BA22 NERVOUS SYSTEM
PSYCHOLEPTICS
ANXIOLYTICS
Benzodiazepine derivatives

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.87 acidic
pKa2 4.63 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Aldo-keto reductase family 1 member C3 Enzyme Ki 5.82 CHEMBL

External reference:

IDSource
D01268 KEGG_DRUG
21311 RXNORM
C0055964 UMLSCUI
CHEBI:31426 CHEBI
CHEMBL2107254 ChEMBL_ID
DB01553 DRUGBANK_ID
C005522 MESH_SUPPLEMENTAL_RECORD_UI
2816 PUBCHEM_CID
3400 INN_ID
GYL649Z0HY UNII
006709 NDDF
16211000122103 SNOMEDCT_US

Pharmaceutical products:

None