clopamide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
diuretics, sulfamoylbenzoic acid derivatives	706	636-54-4

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

brinedine
clopamide
chlosudimeprimyl
clopamidum
brinaldix

A sulfamoylbenzamide piperidine. It is considered a thiazide-like diuretic.

Molecular weight: 345.84
Formula: C14H20ClN3O3S
CLOGP: 2.37
LIPINSKI: 0
HAC: 6
HDO: 2
TPSA: 92.50
ALOGS: -3.40
ROTB: 3

Drug dosage:

Dose	Unit	Route
10	mg	O
10	mg	O

ADMET properties:

Property	Value	Reference
BDDCS (Biopharmaceutical Drug Disposition Classification System)	3	Hosey CM, Chan R, Benet LZ

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	C03BA03	CARDIOVASCULAR SYSTEM DIURETICS LOW-CEILING DIURETICS, EXCL. THIAZIDES Sulfonamides, plain
ATC	C03BB03	CARDIOVASCULAR SYSTEM DIURETICS LOW-CEILING DIURETICS, EXCL. THIAZIDES Sulfonamides and potassium in combination
MeSH PA	D004232	Diuretics
MeSH PA	D045283	Natriuretic Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	8.61	acidic
pKa2	11.42	acidic
pKa3	3.76	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
N0000167202	NUI
D02460	KEGG_DRUG
2603	RXNORM
C0009025	UMLSCUI
CHEBI:94521	CHEBI
CHEMBL1361347	ChEMBL_ID
DB13792	DRUGBANK_ID
D003005	MESH_DESCRIPTOR_UI
12492	PUBCHEM_CID
1517	INN_ID
17S83WON0I	UNII
003711	NDDF
395940005	SNOMEDCT_US
429462003	SNOMEDCT_US

Pharmaceutical products:

None