clonixin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| anti-inflammatory, anilinonicotinic acid derivatives | 705 | 17737-65-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Anti-inflammatory analgesic.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D018712 | Analgesics, Non-Narcotic |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| MeSH PA | D018501 | Antirheumatic Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D018689 | Sensory System Agents |
| CHEBI has role | CHEBI:35475 | non-steroidal anti-inflammatory agent |
| CHEBI has role | CHEBI:35493 | anti-pyretic |
| CHEBI has role | CHEBI:35544 | cyclooxygenase inhibitors |
| CHEBI has role | CHEBI:35620 | vasodilator agents |
| CHEBI has role | CHEBI:35856 | lipoxygenase inhibitors |
| CHEBI has role | CHEBI:50427 | platelet aggregation inhibitors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 1.96 | acidic |
| pKa2 | 5.45 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | IC50 | 4.89 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000167333 | NUI |
| D03555 | KEGG_DRUG |
| 2601 | RXNORM |
| C0009018 | UMLSCUI |
| CHEBI:76200 | CHEBI |
| 6J3 | PDB_CHEM_ID |
| CHEMBL1332971 | ChEMBL_ID |
| DB09218 | DRUGBANK_ID |
| D003002 | MESH_DESCRIPTOR_UI |
| 28718 | PUBCHEM_CID |
| 2718 | INN_ID |
| V7DXN0M42R | UNII |
| 004344 | NDDF |
Pharmaceutical products:
None