Stem definition | Drug id | CAS RN |
---|---|---|
diazepam derivatives | 703 | 1622-61-3 |
Dose | Unit | Route |
---|---|---|
8 | mg | O |
8 | mg | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.10 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 0.42 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 98 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 2.90 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 0.88 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.15 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 38 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
June 4, 1975 | FDA | ROCHE |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Completed suicide | 2406.03 | 10.16 | 2674 | 206929 | 142999 | 63136420 |
Toxicity to various agents | 930.38 | 10.16 | 2325 | 207278 | 244925 | 63034494 |
Suicide attempt | 771.40 | 10.16 | 978 | 208625 | 59940 | 63219479 |
Drug abuse | 593.09 | 10.16 | 945 | 208658 | 71573 | 63207846 |
Contraindicated product administered | 578.90 | 10.16 | 35 | 209568 | 217613 | 63061806 |
Synovitis | 543.52 | 10.16 | 16 | 209587 | 186902 | 63092517 |
Intentional overdose | 534.63 | 10.16 | 913 | 208690 | 73239 | 63206180 |
Suicidal ideation | 504.29 | 10.16 | 809 | 208794 | 61612 | 63217807 |
Systemic lupus erythematosus | 467.43 | 10.16 | 67 | 209536 | 208851 | 63070568 |
Somnolence | 464.86 | 10.16 | 1471 | 208132 | 177214 | 63102205 |
Respiratory arrest | 457.94 | 10.16 | 552 | 209051 | 32093 | 63247326 |
Seizure | 448.02 | 10.16 | 1199 | 208404 | 131435 | 63147984 |
Hand deformity | 432.03 | 10.16 | 23 | 209580 | 159434 | 63119985 |
Depression | 429.94 | 10.16 | 1526 | 208077 | 194966 | 63084453 |
Glossodynia | 410.46 | 10.16 | 53 | 209550 | 178823 | 63100596 |
Drug intolerance | 406.63 | 10.16 | 259 | 209344 | 308402 | 62971017 |
Cardio-respiratory arrest | 396.71 | 10.16 | 711 | 208892 | 59248 | 63220171 |
Sopor | 390.89 | 10.16 | 422 | 209181 | 21742 | 63257677 |
Arthropathy | 358.87 | 10.16 | 163 | 209440 | 234629 | 63044790 |
Overdose | 357.41 | 10.16 | 1009 | 208594 | 114069 | 63165350 |
Drug withdrawal syndrome | 357.40 | 10.16 | 445 | 209158 | 26749 | 63252670 |
Psychotic disorder | 351.21 | 10.16 | 429 | 209174 | 25283 | 63254136 |
Pericarditis | 347.18 | 10.16 | 22 | 209581 | 131557 | 63147862 |
Infusion related reaction | 338.65 | 10.16 | 195 | 209408 | 245326 | 63034093 |
Anxiety | 316.28 | 10.16 | 1489 | 208114 | 216052 | 63063367 |
Joint swelling | 304.34 | 10.16 | 381 | 209222 | 327285 | 62952134 |
Rheumatoid arthritis | 292.52 | 10.16 | 245 | 209358 | 253574 | 63025845 |
Treatment failure | 278.84 | 10.16 | 155 | 209448 | 198888 | 63080531 |
Cardiac arrest | 275.20 | 10.16 | 799 | 208804 | 91746 | 63187673 |
Tremor | 272.81 | 10.16 | 1008 | 208595 | 131231 | 63148188 |
Wound | 272.70 | 10.16 | 99 | 209504 | 163164 | 63116255 |
Helicobacter infection | 265.79 | 10.16 | 9 | 209594 | 92776 | 63186643 |
Alopecia | 265.63 | 10.16 | 441 | 209162 | 337095 | 62942324 |
Swelling | 264.31 | 10.16 | 312 | 209291 | 275066 | 63004353 |
Abdominal discomfort | 253.64 | 10.16 | 418 | 209185 | 320467 | 62958952 |
Schizophrenia | 252.47 | 10.16 | 231 | 209372 | 9721 | 63269698 |
Stubbornness | 251.41 | 10.16 | 79 | 209524 | 292 | 63279127 |
Rash | 247.37 | 10.16 | 984 | 208619 | 559887 | 62719532 |
Rheumatoid factor positive | 246.05 | 10.16 | 7 | 209596 | 84399 | 63195020 |
Drug dependence | 239.58 | 10.16 | 347 | 209256 | 24136 | 63255283 |
Irritability | 230.58 | 10.16 | 392 | 209211 | 31302 | 63248117 |
Hypersensitivity | 225.96 | 10.16 | 387 | 209216 | 292298 | 62987121 |
Panic attack | 217.78 | 10.16 | 316 | 209287 | 22015 | 63257404 |
Agitation | 206.37 | 10.16 | 545 | 209058 | 59212 | 63220207 |
Intentional self-injury | 196.58 | 10.16 | 325 | 209278 | 25362 | 63254057 |
Serotonin syndrome | 192.03 | 10.16 | 342 | 209261 | 28340 | 63251079 |
Maternal exposure during pregnancy | 186.80 | 10.16 | 273 | 209330 | 219789 | 63059630 |
Abnormal behaviour | 183.00 | 10.16 | 285 | 209318 | 21141 | 63258278 |
Poisoning | 182.89 | 10.16 | 226 | 209377 | 13474 | 63265945 |
Folliculitis | 181.79 | 10.16 | 13 | 209590 | 70304 | 63209115 |
Sensitisation | 180.79 | 10.16 | 122 | 209481 | 3264 | 63276155 |
Discomfort | 177.85 | 10.16 | 174 | 209429 | 167200 | 63112219 |
Infection | 176.81 | 10.16 | 303 | 209300 | 228870 | 63050549 |
Therapeutic product effect decreased | 175.66 | 10.16 | 228 | 209375 | 192959 | 63086460 |
Neuroleptic malignant syndrome | 174.17 | 10.16 | 207 | 209396 | 11849 | 63267570 |
Muscle injury | 172.09 | 10.16 | 11 | 209592 | 65334 | 63214085 |
Acute kidney injury | 171.49 | 10.16 | 385 | 209218 | 263030 | 63016389 |
Withdrawal syndrome | 169.41 | 10.16 | 265 | 209338 | 19732 | 63259687 |
General physical health deterioration | 168.82 | 10.16 | 252 | 209351 | 201150 | 63078269 |
Stomatitis | 168.35 | 10.16 | 127 | 209476 | 138598 | 63140821 |
Polycystic ovaries | 167.62 | 10.16 | 130 | 209473 | 4341 | 63275078 |
Unresponsive to stimuli | 158.29 | 10.16 | 347 | 209256 | 33469 | 63245950 |
Thinking abnormal | 157.50 | 10.16 | 185 | 209418 | 10458 | 63268961 |
Insomnia | 157.18 | 10.16 | 1232 | 208371 | 214020 | 63065399 |
Dyskinesia | 155.06 | 10.16 | 333 | 209270 | 31669 | 63247750 |
Mental disorder | 153.31 | 10.16 | 293 | 209310 | 25626 | 63253793 |
Ejection fraction | 151.20 | 10.16 | 96 | 209507 | 2310 | 63277109 |
Anger | 148.13 | 10.16 | 194 | 209409 | 12262 | 63267157 |
Rhinitis allergic | 147.85 | 10.16 | 188 | 209415 | 11539 | 63267880 |
Drug interaction | 144.07 | 10.16 | 1268 | 208335 | 227863 | 63051556 |
Arthralgia | 143.59 | 10.16 | 1198 | 208405 | 568512 | 62710907 |
Febrile neutropenia | 142.99 | 10.16 | 109 | 209494 | 118340 | 63161079 |
Impaired healing | 141.85 | 10.16 | 81 | 209522 | 102461 | 63176958 |
Mood altered | 139.94 | 10.16 | 206 | 209397 | 14537 | 63264882 |
Tardive dyskinesia | 134.56 | 10.16 | 153 | 209450 | 8349 | 63271070 |
Hepatic enzyme increased | 131.39 | 10.16 | 296 | 209307 | 202032 | 63077387 |
Mania | 130.90 | 10.16 | 182 | 209421 | 12185 | 63267234 |
Aggression | 129.69 | 10.16 | 258 | 209345 | 23240 | 63256179 |
Speech disorder | 129.67 | 10.16 | 360 | 209243 | 40269 | 63239150 |
Rheumatic fever | 127.80 | 10.16 | 3 | 209600 | 43108 | 63236311 |
Drug hypersensitivity | 125.50 | 10.16 | 563 | 209040 | 310124 | 62969295 |
Disturbance in attention | 125.48 | 10.16 | 342 | 209261 | 37847 | 63241572 |
Depressed level of consciousness | 125.21 | 10.16 | 470 | 209133 | 61608 | 63217811 |
Crying | 124.89 | 10.16 | 253 | 209350 | 23090 | 63256329 |
Ataxia | 124.06 | 10.16 | 198 | 209405 | 14997 | 63264422 |
Dystonia | 123.89 | 10.16 | 188 | 209415 | 13631 | 63265788 |
Intentional product misuse | 121.86 | 10.16 | 460 | 209143 | 60457 | 63218962 |
Balance disorder | 117.44 | 10.16 | 571 | 209032 | 83851 | 63195568 |
Feeling abnormal | 115.87 | 10.16 | 863 | 208740 | 147529 | 63131890 |
Hyperhidrosis | 115.02 | 10.16 | 678 | 208925 | 107158 | 63172261 |
Nightmare | 114.77 | 10.16 | 218 | 209385 | 18976 | 63260443 |
Off label use | 114.46 | 10.16 | 1555 | 208048 | 672907 | 62606512 |
Anaemia | 110.10 | 10.16 | 546 | 209057 | 292884 | 62986535 |
Lower respiratory tract infection | 109.41 | 10.16 | 167 | 209436 | 132140 | 63147279 |
Restless legs syndrome | 107.77 | 10.16 | 208 | 209395 | 18323 | 63261096 |
Myoglobin urine present | 107.37 | 10.16 | 52 | 209551 | 720 | 63278699 |
Dysarthria | 105.69 | 10.16 | 346 | 209257 | 42365 | 63237054 |
Nervousness | 103.34 | 10.16 | 279 | 209324 | 30700 | 63248719 |
Irritable bowel syndrome | 101.82 | 10.16 | 74 | 209529 | 82338 | 63197081 |
Paranoia | 100.63 | 10.16 | 156 | 209447 | 11523 | 63267896 |
Hallucination | 99.93 | 10.16 | 402 | 209201 | 54415 | 63225004 |
Drug ineffective | 99.60 | 10.16 | 2660 | 206943 | 1042105 | 62237314 |
Drooling | 98.53 | 10.16 | 90 | 209513 | 3778 | 63275641 |
Sedation | 98.38 | 10.16 | 317 | 209286 | 38492 | 63240927 |
Dissociation | 96.85 | 10.16 | 79 | 209524 | 2840 | 63276579 |
Peripheral swelling | 96.25 | 10.16 | 501 | 209102 | 265441 | 63013978 |
Feeling of despair | 94.25 | 10.16 | 71 | 209532 | 2268 | 63277151 |
Muscle rigidity | 94.09 | 10.16 | 150 | 209453 | 11350 | 63268069 |
Mydriasis | 93.80 | 10.16 | 153 | 209450 | 11803 | 63267616 |
Jaundice cholestatic | 93.25 | 10.16 | 118 | 209485 | 7206 | 63272213 |
Thrombocytopenia | 92.61 | 10.16 | 228 | 209375 | 150929 | 63128490 |
Gastric pH decreased | 92.42 | 10.16 | 47 | 209556 | 727 | 63278692 |
Sleep disorder due to general medical condition, insomnia type | 91.75 | 10.16 | 29 | 209574 | 52188 | 63227231 |
Product use issue | 90.55 | 10.16 | 397 | 209206 | 220123 | 63059296 |
Multiple sclerosis | 89.99 | 10.16 | 228 | 209375 | 24144 | 63255275 |
Diarrhoea | 89.54 | 10.16 | 1745 | 207858 | 713621 | 62565798 |
Neutropenia | 88.76 | 10.16 | 289 | 209314 | 174716 | 63104703 |
Gastrointestinal disorder | 88.45 | 10.16 | 188 | 209415 | 131051 | 63148368 |
Atrial fibrillation | 88.23 | 10.16 | 156 | 209447 | 116480 | 63162939 |
Disease progression | 86.85 | 10.16 | 171 | 209432 | 122587 | 63156832 |
Amnesia | 86.12 | 10.16 | 388 | 209215 | 55197 | 63224222 |
Drug withdrawal convulsions | 84.95 | 10.16 | 55 | 209548 | 1370 | 63278049 |
Cogwheel rigidity | 84.31 | 10.16 | 62 | 209541 | 1908 | 63277511 |
Mood swings | 82.84 | 10.16 | 185 | 209418 | 18063 | 63261356 |
Urinary tract discomfort | 81.51 | 10.16 | 41 | 209562 | 619 | 63278800 |
Hypersomnia | 79.68 | 10.16 | 181 | 209422 | 17874 | 63261545 |
Memory impairment | 79.46 | 10.16 | 603 | 209000 | 103655 | 63175764 |
Sleep apnoea syndrome | 79.38 | 10.16 | 244 | 209359 | 28889 | 63250530 |
Hip arthroplasty | 79.30 | 10.16 | 29 | 209574 | 47617 | 63231802 |
Loss of consciousness | 78.48 | 10.16 | 662 | 208941 | 117459 | 63161960 |
Bipolar disorder | 78.12 | 10.16 | 113 | 209490 | 7847 | 63271572 |
Restlessness | 77.77 | 10.16 | 244 | 209359 | 29209 | 63250210 |
Multiple sclerosis relapse | 77.06 | 10.16 | 341 | 209262 | 48137 | 63231282 |
Derealisation | 75.41 | 10.16 | 48 | 209555 | 1160 | 63278259 |
Multiple-drug resistance | 75.06 | 10.16 | 89 | 209514 | 5081 | 63274338 |
Hallucination, auditory | 74.64 | 10.16 | 144 | 209459 | 12680 | 63266739 |
Product substitution issue | 73.55 | 10.16 | 163 | 209440 | 15833 | 63263586 |
Carpal tunnel syndrome | 72.99 | 10.16 | 191 | 209412 | 20626 | 63258793 |
Ill-defined disorder | 72.69 | 10.16 | 98 | 209505 | 81657 | 63197762 |
Malignant neoplasm progression | 72.45 | 10.16 | 99 | 209504 | 82022 | 63197397 |
Psoriatic arthropathy | 72.34 | 10.16 | 119 | 209484 | 91401 | 63188018 |
Alveolar osteitis | 72.18 | 10.16 | 42 | 209561 | 859 | 63278560 |
Nasopharyngitis | 71.12 | 10.16 | 519 | 209084 | 253738 | 63025681 |
Blood test abnormal | 70.45 | 10.16 | 158 | 209445 | 15471 | 63263948 |
Tunnel vision | 70.20 | 10.16 | 46 | 209557 | 1170 | 63278249 |
Liver injury | 70.11 | 10.16 | 58 | 209545 | 60462 | 63218957 |
Bradyphrenia | 69.84 | 10.16 | 100 | 209503 | 6880 | 63272539 |
Blister | 69.60 | 10.16 | 209 | 209394 | 129605 | 63149814 |
Emotional disorder | 68.02 | 10.16 | 142 | 209461 | 13237 | 63266182 |
Vision blurred | 68.00 | 10.16 | 528 | 209075 | 91396 | 63188023 |
Knee arthroplasty | 67.83 | 10.16 | 48 | 209555 | 54158 | 63225261 |
Coma | 67.51 | 10.16 | 403 | 209200 | 63961 | 63215458 |
Hypokinesia | 67.48 | 10.16 | 145 | 209458 | 13791 | 63265628 |
Hypoaesthesia oral | 67.05 | 10.16 | 139 | 209464 | 12894 | 63266525 |
Sepsis | 66.95 | 10.16 | 269 | 209334 | 152854 | 63126565 |
Head injury | 66.93 | 10.16 | 221 | 209382 | 27175 | 63252244 |
Mobility decreased | 66.45 | 10.16 | 193 | 209410 | 120966 | 63158453 |
Myelosuppression | 65.48 | 10.16 | 3 | 209600 | 23700 | 63255719 |
Delusion | 65.18 | 10.16 | 131 | 209472 | 11886 | 63267533 |
Toxic encephalopathy | 63.99 | 10.16 | 93 | 209510 | 6486 | 63272933 |
Lethargy | 63.51 | 10.16 | 358 | 209245 | 55649 | 63223770 |
Pleural effusion | 63.23 | 10.16 | 133 | 209470 | 93077 | 63186342 |
Disorientation | 63.08 | 10.16 | 278 | 209325 | 39174 | 63240245 |
Burning sensation | 61.84 | 10.16 | 348 | 209255 | 54059 | 63225360 |
Movement disorder | 61.44 | 10.16 | 184 | 209419 | 21477 | 63257942 |
Gait disturbance | 61.20 | 10.16 | 896 | 208707 | 182282 | 63097137 |
C-reactive protein increased | 61.06 | 10.16 | 139 | 209464 | 94568 | 63184851 |
Mental status changes | 61.02 | 10.16 | 276 | 209327 | 39323 | 63240096 |
Status epilepticus | 60.99 | 10.16 | 147 | 209456 | 15086 | 63264333 |
Pancytopenia | 60.30 | 10.16 | 145 | 209458 | 96788 | 63182631 |
H1N1 influenza | 59.68 | 10.16 | 48 | 209555 | 1691 | 63277728 |
Interstitial lung disease | 59.42 | 10.16 | 70 | 209533 | 61838 | 63217581 |
Bladder pain | 59.37 | 10.16 | 54 | 209549 | 2254 | 63277165 |
Animal scratch | 59.27 | 10.16 | 44 | 209559 | 1374 | 63278045 |
Renal impairment | 59.16 | 10.16 | 127 | 209476 | 88228 | 63191191 |
Akathisia | 58.58 | 10.16 | 107 | 209496 | 9039 | 63270380 |
Depersonalisation/derealisation disorder | 58.31 | 10.16 | 43 | 209560 | 1329 | 63278090 |
Respiratory depression | 57.78 | 10.16 | 135 | 209468 | 13580 | 63265839 |
Pulmonary fibrosis | 57.13 | 10.16 | 30 | 209573 | 39779 | 63239640 |
Drug screen negative | 57.03 | 10.16 | 25 | 209578 | 271 | 63279148 |
Nephrectomy | 56.86 | 10.16 | 44 | 209559 | 1464 | 63277955 |
Nasal polyps | 56.76 | 10.16 | 84 | 209519 | 5955 | 63273464 |
Incontinence | 56.29 | 10.16 | 121 | 209482 | 11511 | 63267908 |
Fall | 56.28 | 10.16 | 1694 | 207909 | 390640 | 62888779 |
Mucosal inflammation | 55.57 | 10.16 | 44 | 209559 | 46884 | 63232535 |
Epilepsy | 55.45 | 10.16 | 206 | 209397 | 26859 | 63252560 |
Stress | 55.45 | 10.16 | 396 | 209207 | 66771 | 63212648 |
On and off phenomenon | 55.35 | 10.16 | 47 | 209556 | 1788 | 63277631 |
Sleep disorder due to a general medical condition | 54.69 | 10.16 | 123 | 209480 | 12065 | 63267354 |
Exposure via ingestion | 54.12 | 10.16 | 57 | 209546 | 2852 | 63276567 |
Bradykinesia | 52.90 | 10.16 | 75 | 209528 | 5113 | 63274306 |
Ejection fraction abnormal | 52.38 | 10.16 | 45 | 209558 | 1740 | 63277679 |
Musculoskeletal stiffness | 52.00 | 10.16 | 376 | 209227 | 184242 | 63095177 |
Myocardial stunning | 51.69 | 10.16 | 20 | 209583 | 153 | 63279266 |
Migraine | 51.54 | 10.16 | 545 | 209058 | 102801 | 63176618 |
Electrocardiogram QT prolonged | 51.50 | 10.16 | 355 | 209248 | 59175 | 63220244 |
Heart rate increased | 51.31 | 10.16 | 506 | 209097 | 93732 | 63185687 |
Gastrointestinal haemorrhage | 50.83 | 10.16 | 121 | 209482 | 81055 | 63198364 |
Abnormal dreams | 50.44 | 10.16 | 109 | 209494 | 10407 | 63269012 |
Depressed mood | 50.35 | 10.16 | 264 | 209339 | 39927 | 63239492 |
Therapeutic response unexpected | 50.07 | 10.16 | 156 | 209447 | 18603 | 63260816 |
Intentional product use issue | 49.61 | 10.16 | 235 | 209368 | 127657 | 63151762 |
Granulocytopenia | 49.20 | 10.16 | 76 | 209527 | 5596 | 63273823 |
Feeling of body temperature change | 48.76 | 10.16 | 70 | 209533 | 4827 | 63274592 |
Hyperprolactinaemia | 48.33 | 10.16 | 62 | 209541 | 3838 | 63275581 |
Substance abuse | 48.29 | 10.16 | 69 | 209534 | 4738 | 63274681 |
Major depression | 47.85 | 10.16 | 91 | 209512 | 7927 | 63271492 |
Sluggishness | 47.68 | 10.16 | 72 | 209531 | 5197 | 63274222 |
Parkinsonism | 47.57 | 10.16 | 106 | 209497 | 10333 | 63269086 |
Pain | 47.02 | 10.16 | 1984 | 207619 | 738644 | 62540775 |
Inflammation | 45.87 | 10.16 | 130 | 209473 | 82143 | 63197276 |
Pneumonia aspiration | 45.43 | 10.16 | 230 | 209373 | 34310 | 63245109 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 44.94 | 10.16 | 44 | 209559 | 2017 | 63277402 |
Blood creatine phosphokinase increased | 44.59 | 10.16 | 209 | 209394 | 30221 | 63249198 |
Adverse drug reaction | 44.41 | 10.16 | 126 | 209477 | 79588 | 63199831 |
Paranasal sinus discomfort | 44.23 | 10.16 | 63 | 209540 | 4313 | 63275106 |
Platelet count decreased | 44.09 | 10.16 | 215 | 209388 | 115907 | 63163512 |
Muscle spasms | 43.86 | 10.16 | 742 | 208861 | 155408 | 63124011 |
Dysphoria | 43.72 | 10.16 | 67 | 209536 | 4899 | 63274520 |
Pleurothotonus | 43.69 | 10.16 | 36 | 209567 | 1313 | 63278106 |
Decorticate posture | 43.67 | 10.16 | 21 | 209582 | 286 | 63279133 |
Bone marrow failure | 43.64 | 10.16 | 21 | 209582 | 29269 | 63250150 |
Hypercalcaemia | 42.67 | 10.16 | 20 | 209583 | 28302 | 63251117 |
Influenza like illness | 42.51 | 10.16 | 371 | 209232 | 66453 | 63212966 |
Galactorrhoea | 42.26 | 10.16 | 60 | 209543 | 4095 | 63275324 |
Myocardial depression | 41.72 | 10.16 | 24 | 209579 | 480 | 63278939 |
Menstrual disorder | 41.69 | 10.16 | 68 | 209535 | 5245 | 63274174 |
Generalised tonic-clonic seizure | 41.58 | 10.16 | 198 | 209405 | 28818 | 63250601 |
Aphasia | 41.50 | 10.16 | 217 | 209386 | 32783 | 63246636 |
Neutrophil count decreased | 41.25 | 10.16 | 77 | 209526 | 56329 | 63223090 |
Broncholithiasis | 41.20 | 10.16 | 19 | 209584 | 234 | 63279185 |
Urinary retention | 40.01 | 10.16 | 202 | 209401 | 30099 | 63249320 |
Skin ulcer | 39.90 | 10.16 | 50 | 209553 | 42995 | 63236424 |
Personality disorder | 39.80 | 10.16 | 70 | 209533 | 5741 | 63273678 |
Musculoskeletal pain | 39.75 | 10.16 | 163 | 209440 | 92114 | 63187305 |
Emotional distress | 39.54 | 10.16 | 212 | 209391 | 32337 | 63247082 |
Cardiac failure | 39.32 | 10.16 | 156 | 209447 | 88986 | 63190433 |
Cholelithiasis | 39.22 | 10.16 | 264 | 209339 | 43661 | 63235758 |
Amylase increased | 39.09 | 10.16 | 73 | 209530 | 6272 | 63273147 |
Therapeutic product ineffective | 38.96 | 10.16 | 38 | 209565 | 1734 | 63277685 |
Atonic seizures | 38.92 | 10.16 | 25 | 209578 | 614 | 63278805 |
Stoma site discharge | 38.41 | 10.16 | 36 | 209567 | 1562 | 63277857 |
Hallucinations, mixed | 38.15 | 10.16 | 62 | 209541 | 4767 | 63274652 |
Lactic acidosis | 38.14 | 10.16 | 42 | 209561 | 38245 | 63241174 |
Drug tolerance decreased | 38.11 | 10.16 | 6 | 209597 | 17467 | 63261952 |
Melaena | 37.84 | 10.16 | 27 | 209576 | 30338 | 63249081 |
Nystagmus | 37.62 | 10.16 | 71 | 209532 | 6149 | 63273270 |
Fear | 37.46 | 10.16 | 126 | 209477 | 15640 | 63263779 |
Breast hyperplasia | 37.41 | 10.16 | 19 | 209584 | 293 | 63279126 |
Middle insomnia | 37.38 | 10.16 | 109 | 209494 | 12534 | 63266885 |
Miosis | 37.33 | 10.16 | 78 | 209525 | 7275 | 63272144 |
Electroencephalogram abnormal | 37.31 | 10.16 | 53 | 209550 | 3619 | 63275800 |
Dopamine dysregulation syndrome | 37.28 | 10.16 | 16 | 209587 | 164 | 63279255 |
Asthma | 37.23 | 10.16 | 610 | 208993 | 126951 | 63152468 |
Hostility | 37.20 | 10.16 | 38 | 209565 | 1834 | 63277585 |
Impaired driving ability | 37.12 | 10.16 | 59 | 209544 | 4452 | 63274967 |
Macular degeneration | 37.05 | 10.16 | 17 | 209586 | 24359 | 63255060 |
Rubber sensitivity | 36.97 | 10.16 | 42 | 209561 | 2289 | 63277130 |
Blood creatinine increased | 36.71 | 10.16 | 157 | 209446 | 87687 | 63191732 |
Palmar-plantar erythrodysaesthesia syndrome | 36.65 | 10.16 | 15 | 209588 | 23000 | 63256419 |
Psychomotor hyperactivity | 36.53 | 10.16 | 97 | 209506 | 10566 | 63268853 |
Bronchopulmonary aspergillosis allergic | 36.35 | 10.16 | 41 | 209562 | 2217 | 63277202 |
Drug screen positive | 36.32 | 10.16 | 52 | 209551 | 3577 | 63275842 |
Lymph node calcification | 36.30 | 10.16 | 19 | 209584 | 313 | 63279106 |
Catatonia | 36.08 | 10.16 | 58 | 209545 | 4419 | 63275000 |
Red blood cell sedimentation rate increased | 35.87 | 10.16 | 56 | 209547 | 43926 | 63235493 |
Sinus pain | 35.81 | 10.16 | 50 | 209553 | 3360 | 63276059 |
Coma blister | 35.72 | 10.16 | 15 | 209588 | 145 | 63279274 |
Libido increased | 35.64 | 10.16 | 32 | 209571 | 1313 | 63278106 |
Cardiac disorder | 35.43 | 10.16 | 288 | 209315 | 50528 | 63228891 |
Drug use disorder | 35.39 | 10.16 | 61 | 209542 | 4923 | 63274496 |
Dizziness | 35.04 | 10.16 | 1745 | 207858 | 428180 | 62851239 |
Sleep-related eating disorder | 34.66 | 10.16 | 26 | 209577 | 825 | 63278594 |
Product complaint | 34.63 | 10.16 | 107 | 209496 | 12702 | 63266717 |
Bone erosion | 34.58 | 10.16 | 8 | 209595 | 17709 | 63261710 |
Hyperkalaemia | 34.57 | 10.16 | 80 | 209523 | 54123 | 63225296 |
Septic shock | 34.47 | 10.16 | 109 | 209494 | 66520 | 63212899 |
Ear congestion | 34.41 | 10.16 | 44 | 209559 | 2715 | 63276704 |
Live birth | 34.36 | 10.16 | 21 | 209582 | 25609 | 63253810 |
Pneumocystis jirovecii pneumonia | 34.31 | 10.16 | 7 | 209596 | 16907 | 63262512 |
Incoherent | 34.23 | 10.16 | 57 | 209546 | 4473 | 63274946 |
Muscle disorder | 34.22 | 10.16 | 60 | 209543 | 4909 | 63274510 |
Hypothyroidism | 33.83 | 10.16 | 249 | 209354 | 42383 | 63237036 |
Suspected suicide | 33.73 | 10.16 | 70 | 209533 | 6498 | 63272921 |
Osmolar gap increased | 33.54 | 10.16 | 13 | 209590 | 100 | 63279319 |
Hypoventilation | 33.51 | 10.16 | 58 | 209545 | 4696 | 63274723 |
Urinary incontinence | 33.27 | 10.16 | 200 | 209403 | 31814 | 63247605 |
Limb injury | 33.05 | 10.16 | 169 | 209434 | 25308 | 63254111 |
Oromandibular dystonia | 33.05 | 10.16 | 21 | 209582 | 506 | 63278913 |
Herpes zoster | 32.87 | 10.16 | 150 | 209453 | 82312 | 63197107 |
Decompression sickness | 32.68 | 10.16 | 12 | 209591 | 78 | 63279341 |
Oropharyngeal oedema | 32.63 | 10.16 | 18 | 209585 | 331 | 63279088 |
Persecutory delusion | 32.47 | 10.16 | 43 | 209560 | 2747 | 63276672 |
Osteonecrosis of jaw | 32.34 | 10.16 | 41 | 209562 | 35082 | 63244337 |
Total lung capacity increased | 32.28 | 10.16 | 39 | 209564 | 2271 | 63277148 |
Nasal oedema | 32.27 | 10.16 | 32 | 209571 | 1490 | 63277929 |
Mutism | 32.23 | 10.16 | 33 | 209570 | 1597 | 63277822 |
Exposure during pregnancy | 32.17 | 10.16 | 343 | 209260 | 155204 | 63124215 |
Autonomic nervous system imbalance | 32.13 | 10.16 | 43 | 209560 | 2775 | 63276644 |
Cardiac failure congestive | 31.79 | 10.16 | 177 | 209426 | 92256 | 63187163 |
Angioedema | 31.23 | 10.16 | 70 | 209533 | 47895 | 63231524 |
Tension | 31.05 | 10.16 | 45 | 209558 | 3130 | 63276289 |
Pruritus | 30.63 | 10.16 | 934 | 208669 | 360519 | 62918900 |
Parosmia | 30.54 | 10.16 | 65 | 209538 | 6141 | 63273278 |
Forced expiratory volume decreased | 30.41 | 10.16 | 57 | 209546 | 4911 | 63274508 |
Weight increased | 30.37 | 10.16 | 1099 | 208504 | 259693 | 63019726 |
Bruxism | 30.25 | 10.16 | 47 | 209556 | 3478 | 63275941 |
Secretion discharge | 30.17 | 10.16 | 99 | 209504 | 12132 | 63267287 |
Feeling jittery | 29.99 | 10.16 | 105 | 209498 | 13298 | 63266121 |
Dysphagia | 29.82 | 10.16 | 434 | 209169 | 88151 | 63191268 |
Extrapyramidal disorder | 29.67 | 10.16 | 104 | 209499 | 13180 | 63266239 |
Liver function test increased | 29.49 | 10.16 | 39 | 209564 | 32772 | 63246647 |
Post-traumatic stress disorder | 29.39 | 10.16 | 58 | 209545 | 5193 | 63274226 |
Adjustment disorder with mixed anxiety and depressed mood | 29.33 | 10.16 | 12 | 209591 | 108 | 63279311 |
Obsessive-compulsive disorder | 29.23 | 10.16 | 50 | 209553 | 4010 | 63275409 |
Hypocalcaemia | 29.22 | 10.16 | 37 | 209566 | 31676 | 63247743 |
Ketosis-prone diabetes mellitus | 29.00 | 10.16 | 8 | 209595 | 16 | 63279403 |
Developmental glaucoma | 28.94 | 10.16 | 10 | 209593 | 53 | 63279366 |
Creatinine renal clearance decreased | 28.75 | 10.16 | 9 | 209594 | 16299 | 63263120 |
Dyspnoea | 28.46 | 10.16 | 1842 | 207761 | 659471 | 62619948 |
Cytomegalovirus infection | 28.32 | 10.16 | 17 | 209586 | 20935 | 63258484 |
Peripheral venous disease | 28.27 | 10.16 | 8 | 209595 | 15469 | 63263950 |
Panic disorder | 28.24 | 10.16 | 39 | 209564 | 2594 | 63276825 |
Suicidal behaviour | 28.17 | 10.16 | 39 | 209564 | 2600 | 63276819 |
Rash pruritic | 28.09 | 10.16 | 102 | 209501 | 59697 | 63219722 |
Plasma cell myeloma | 28.07 | 10.16 | 47 | 209556 | 35858 | 63243561 |
Muscle twitching | 28.03 | 10.16 | 134 | 209469 | 19534 | 63259885 |
Anticonvulsant drug level above therapeutic | 28 | 10.16 | 19 | 209584 | 513 | 63278906 |
Lupus-like syndrome | 27.76 | 10.16 | 8 | 209595 | 15287 | 63264132 |
Polymyalgia rheumatica | 27.71 | 10.16 | 47 | 209556 | 3744 | 63275675 |
Dysgraphia | 27.46 | 10.16 | 43 | 209560 | 3203 | 63276216 |
Freezing phenomenon | 27.45 | 10.16 | 27 | 209576 | 1245 | 63278174 |
Therapy non-responder | 27.39 | 10.16 | 143 | 209460 | 75758 | 63203661 |
Euphoric mood | 27.37 | 10.16 | 54 | 209549 | 4833 | 63274586 |
Neutropenic sepsis | 27.36 | 10.16 | 10 | 209593 | 16428 | 63262991 |
Neoplasm progression | 27.28 | 10.16 | 49 | 209554 | 36379 | 63243040 |
Formication | 27.23 | 10.16 | 50 | 209553 | 4241 | 63275178 |
Blood urine present | 27.04 | 10.16 | 110 | 209493 | 14959 | 63264460 |
Troponin increased | 26.86 | 10.16 | 84 | 209519 | 10037 | 63269382 |
Wound complication | 26.79 | 10.16 | 46 | 209557 | 3701 | 63275718 |
Gastrooesophageal reflux disease | 26.67 | 10.16 | 454 | 209149 | 95185 | 63184234 |
Urinary bladder rupture | 26.45 | 10.16 | 12 | 209591 | 142 | 63279277 |
Blood cholesterol increased | 26.22 | 10.16 | 192 | 209411 | 93840 | 63185579 |
Weight abnormal | 26.20 | 10.16 | 27 | 209576 | 1317 | 63278102 |
Paralysis | 26.12 | 10.16 | 82 | 209521 | 9818 | 63269601 |
Right ventricular failure | 26.11 | 10.16 | 12 | 209591 | 17176 | 63262243 |
Leukopenia | 26.04 | 10.16 | 149 | 209454 | 77141 | 63202278 |
Intervertebral disc protrusion | 25.85 | 10.16 | 150 | 209453 | 23559 | 63255860 |
Altered state of consciousness | 25.82 | 10.16 | 157 | 209446 | 25073 | 63254346 |
Post-traumatic neck syndrome | 25.75 | 10.16 | 33 | 209570 | 2041 | 63277378 |
Disorganised speech | 25.72 | 10.16 | 26 | 209577 | 1239 | 63278180 |
Head titubation | 25.71 | 10.16 | 22 | 209581 | 846 | 63278573 |
Psychomotor retardation | 25.71 | 10.16 | 46 | 209557 | 3824 | 63275595 |
Antipsychotic drug level increased | 25.66 | 10.16 | 43 | 209560 | 3392 | 63276027 |
Blood sodium decreased | 25.52 | 10.16 | 152 | 209451 | 24100 | 63255319 |
Affect lability | 25.51 | 10.16 | 88 | 209515 | 11063 | 63268356 |
Apathy | 25.22 | 10.16 | 75 | 209528 | 8719 | 63270700 |
Intellectual disability | 25.22 | 10.16 | 24 | 209579 | 1062 | 63278357 |
Hereditary angioedema | 25.11 | 10.16 | 68 | 209535 | 7494 | 63271925 |
Attention deficit hyperactivity disorder | 24.99 | 10.16 | 40 | 209563 | 3036 | 63276383 |
Pollakiuria | 24.99 | 10.16 | 168 | 209435 | 27769 | 63251650 |
Tinnitus | 24.88 | 10.16 | 202 | 209401 | 35426 | 63243993 |
Pyrexia | 24.80 | 10.16 | 1285 | 208318 | 469193 | 62810226 |
Haematochezia | 24.71 | 10.16 | 92 | 209511 | 53452 | 63225967 |
Renal disorder | 24.70 | 10.16 | 190 | 209413 | 32784 | 63246635 |
Salivary hypersecretion | 24.52 | 10.16 | 68 | 209535 | 7598 | 63271821 |
Bronchiectasis | 24.49 | 10.16 | 112 | 209491 | 16030 | 63263389 |
Sensory loss | 24.48 | 10.16 | 82 | 209521 | 10156 | 63269263 |
Sebaceous gland infection | 24.47 | 10.16 | 12 | 209591 | 171 | 63279248 |
Panic reaction | 24.45 | 10.16 | 47 | 209556 | 4127 | 63275292 |
Choking | 24.40 | 10.16 | 80 | 209523 | 9799 | 63269620 |
Device expulsion | 24.38 | 10.16 | 49 | 209554 | 34873 | 63244546 |
Coordination abnormal | 24.29 | 10.16 | 100 | 209503 | 13673 | 63265746 |
Hypomania | 24.18 | 10.16 | 60 | 209543 | 6270 | 63273149 |
COVID-19 | 23.95 | 10.16 | 248 | 209355 | 112855 | 63166564 |
Tachyphrenia | 23.93 | 10.16 | 26 | 209577 | 1348 | 63278071 |
Concussion | 23.87 | 10.16 | 76 | 209527 | 9168 | 63270251 |
Lung disorder | 23.78 | 10.16 | 115 | 209488 | 62146 | 63217273 |
Logorrhoea | 23.71 | 10.16 | 35 | 209568 | 2475 | 63276944 |
Anorgasmia | 23.63 | 10.16 | 18 | 209585 | 585 | 63278834 |
Conversion disorder | 23.38 | 10.16 | 29 | 209574 | 1735 | 63277684 |
Neuropathy peripheral | 23.35 | 10.16 | 251 | 209352 | 113416 | 63166003 |
Alcohol abuse | 23.34 | 10.16 | 32 | 209571 | 2114 | 63277305 |
Sinusitis | 23.23 | 10.16 | 570 | 209033 | 226083 | 63053336 |
Upper gastrointestinal haemorrhage | 23.18 | 10.16 | 17 | 209586 | 18835 | 63260584 |
Tongue discolouration | 23.02 | 10.16 | 39 | 209564 | 3104 | 63276315 |
Renal failure | 22.90 | 10.16 | 263 | 209340 | 117389 | 63162030 |
Transplant rejection | 22.85 | 10.16 | 4 | 209599 | 10776 | 63268643 |
Drug detoxification | 22.76 | 10.16 | 14 | 209589 | 318 | 63279101 |
Somnambulism | 22.74 | 10.16 | 54 | 209549 | 5489 | 63273930 |
Arthritis | 22.62 | 10.16 | 259 | 209344 | 115662 | 63163757 |
Proteinuria | 22.60 | 10.16 | 18 | 209585 | 19127 | 63260292 |
Aspiration | 22.57 | 10.16 | 83 | 209520 | 10768 | 63268651 |
Diverticulitis | 22.42 | 10.16 | 62 | 209541 | 39495 | 63239924 |
Drug abuser | 22.38 | 10.16 | 37 | 209566 | 2886 | 63276533 |
Wound secretion | 22.33 | 10.16 | 48 | 209555 | 4566 | 63274853 |
Myoclonic epilepsy | 22.32 | 10.16 | 24 | 209579 | 1230 | 63278189 |
Heart rate abnormal | 22.28 | 10.16 | 50 | 209553 | 4897 | 63274522 |
Incorrect dose administered | 22.28 | 10.16 | 299 | 209304 | 59669 | 63219750 |
Blood iron decreased | 22.22 | 10.16 | 102 | 209501 | 14619 | 63264800 |
Abulia | 22.20 | 10.16 | 16 | 209587 | 477 | 63278942 |
Blood parathyroid hormone decreased | 22.20 | 10.16 | 3 | 209600 | 9788 | 63269631 |
Libido decreased | 22.06 | 10.16 | 35 | 209568 | 2637 | 63276782 |
Coma scale abnormal | 22.01 | 10.16 | 51 | 209552 | 5102 | 63274317 |
Tic | 21.79 | 10.16 | 26 | 209577 | 1494 | 63277925 |
Social anxiety disorder | 21.75 | 10.16 | 15 | 209588 | 416 | 63279003 |
Soft tissue injury | 21.64 | 10.16 | 27 | 209576 | 1625 | 63277794 |
Feeling cold | 21.58 | 10.16 | 144 | 209459 | 23744 | 63255675 |
Stereotypy | 21.41 | 10.16 | 15 | 209588 | 427 | 63278992 |
Anaphylactic shock | 21.33 | 10.16 | 28 | 209575 | 23605 | 63255814 |
Dysstasia | 21.21 | 10.16 | 131 | 209472 | 21035 | 63258384 |
Cytopenia | 21.18 | 10.16 | 6 | 209597 | 11595 | 63267824 |
Pulmonary arterial hypertension | 21.16 | 10.16 | 26 | 209577 | 22551 | 63256868 |
Dependence | 21.14 | 10.16 | 30 | 209573 | 2047 | 63277372 |
Tearfulness | 21.12 | 10.16 | 44 | 209559 | 4095 | 63275324 |
Band neutrophil percentage increased | 21.04 | 10.16 | 12 | 209591 | 236 | 63279183 |
Respiratory rate decreased | 20.95 | 10.16 | 40 | 209563 | 3495 | 63275924 |
Impulsive behaviour | 20.94 | 10.16 | 26 | 209577 | 1557 | 63277862 |
Facet joint syndrome | 20.86 | 10.16 | 7 | 209596 | 12131 | 63267288 |
Peroneal nerve palsy | 20.81 | 10.16 | 48 | 209555 | 4787 | 63274632 |
Adverse event | 20.78 | 10.16 | 134 | 209469 | 67425 | 63211994 |
Decreased interest | 20.75 | 10.16 | 38 | 209565 | 3216 | 63276203 |
Urticaria | 20.72 | 10.16 | 404 | 209199 | 165398 | 63114021 |
Stoma site hypergranulation | 20.61 | 10.16 | 13 | 209590 | 309 | 63279110 |
Mental impairment | 20.59 | 10.16 | 97 | 209506 | 14054 | 63265365 |
White blood cell count decreased | 20.55 | 10.16 | 329 | 209274 | 138775 | 63140644 |
Haemoglobin urine | 20.55 | 10.16 | 10 | 209593 | 140 | 63279279 |
Hyperammonaemia | 20.42 | 10.16 | 50 | 209553 | 5182 | 63274237 |
Myoclonus | 20.40 | 10.16 | 105 | 209498 | 15763 | 63263656 |
Anaphylactic reaction | 20.39 | 10.16 | 131 | 209472 | 65969 | 63213450 |
Anion gap increased | 20.37 | 10.16 | 28 | 209575 | 1854 | 63277565 |
Bursitis | 20.30 | 10.16 | 59 | 209544 | 36982 | 63242437 |
Sputum discoloured | 20.21 | 10.16 | 107 | 209496 | 16240 | 63263179 |
Bipolar I disorder | 20.17 | 10.16 | 28 | 209575 | 1871 | 63277548 |
Ascites | 20.11 | 10.16 | 68 | 209535 | 40660 | 63238759 |
Erythema | 19.97 | 10.16 | 435 | 209168 | 175316 | 63104103 |
Psychotic disorder due to a general medical condition | 19.85 | 10.16 | 12 | 209591 | 264 | 63279155 |
Dysuria | 19.76 | 10.16 | 184 | 209419 | 33554 | 63245865 |
Hypothermia | 19.69 | 10.16 | 93 | 209510 | 13488 | 63265931 |
Colitis | 19.50 | 10.16 | 88 | 209515 | 48440 | 63230979 |
Screaming | 19.44 | 10.16 | 37 | 209566 | 3225 | 63276194 |
Sexual abuse | 19.44 | 10.16 | 11 | 209592 | 213 | 63279206 |
Hypertension | 19.38 | 10.16 | 740 | 208863 | 278563 | 63000856 |
Hyperreflexia | 19.34 | 10.16 | 53 | 209550 | 5881 | 63273538 |
Antidepressant drug level above therapeutic | 19.26 | 10.16 | 14 | 209589 | 423 | 63278996 |
Condition aggravated | 19.24 | 10.16 | 1109 | 208494 | 401108 | 62878311 |
Stoma site pain | 19.16 | 10.16 | 20 | 209583 | 990 | 63278429 |
Acute myeloid leukaemia | 19.16 | 10.16 | 17 | 209586 | 17130 | 63262289 |
Inappropriate schedule of product administration | 19.15 | 10.16 | 464 | 209139 | 103501 | 63175918 |
Food craving | 19.07 | 10.16 | 25 | 209578 | 1581 | 63277838 |
Type 2 diabetes mellitus | 18.98 | 10.16 | 128 | 209475 | 63740 | 63215679 |
Fatigue | 18.94 | 10.16 | 2607 | 206996 | 885421 | 62393998 |
Weight gain poor | 18.94 | 10.16 | 19 | 209584 | 897 | 63278522 |
Hyperammonaemic encephalopathy | 18.89 | 10.16 | 31 | 209572 | 2403 | 63277016 |
Hypervolaemia | 18.88 | 10.16 | 41 | 209562 | 28372 | 63251047 |
Obstructive airways disorder | 18.83 | 10.16 | 125 | 209478 | 20574 | 63258845 |
Wound infection | 18.69 | 10.16 | 26 | 209577 | 21384 | 63258035 |
Hypomagnesaemia | 18.66 | 10.16 | 42 | 209561 | 28695 | 63250724 |
Anticonvulsant drug level increased | 18.62 | 10.16 | 24 | 209579 | 1493 | 63277926 |
Osteoporosis | 18.53 | 10.16 | 112 | 209491 | 57226 | 63222193 |
Anticonvulsant drug level below therapeutic | 18.53 | 10.16 | 16 | 209587 | 623 | 63278796 |
Blood triglycerides increased | 18.46 | 10.16 | 86 | 209517 | 12402 | 63267017 |
Seizure cluster | 18.40 | 10.16 | 11 | 209592 | 237 | 63279182 |
Cerebellar atrophy | 18.27 | 10.16 | 17 | 209586 | 731 | 63278688 |
Hyperthermia | 18.18 | 10.16 | 69 | 209534 | 9087 | 63270332 |
Self-injurious ideation | 18.17 | 10.16 | 32 | 209571 | 2627 | 63276792 |
Hyponatraemia | 17.78 | 10.16 | 261 | 209342 | 111639 | 63167780 |
Fibrous histiocytoma | 17.64 | 10.16 | 15 | 209588 | 572 | 63278847 |
Enuresis | 17.63 | 10.16 | 31 | 209572 | 2542 | 63276877 |
Blood prolactin increased | 17.60 | 10.16 | 37 | 209566 | 3466 | 63275953 |
Joint range of motion decreased | 17.52 | 10.16 | 52 | 209551 | 32376 | 63247043 |
Change in seizure presentation | 17.40 | 10.16 | 13 | 209590 | 410 | 63279009 |
Psychiatric symptom | 17.37 | 10.16 | 47 | 209556 | 5176 | 63274243 |
Vertigo | 17.32 | 10.16 | 286 | 209317 | 59601 | 63219818 |
Basal cell carcinoma | 17.30 | 10.16 | 42 | 209561 | 27949 | 63251470 |
Myelocyte percentage increased | 17.21 | 10.16 | 10 | 209593 | 204 | 63279215 |
Hypnopompic hallucination | 17.20 | 10.16 | 7 | 209596 | 62 | 63279357 |
Trismus | 17.20 | 10.16 | 39 | 209564 | 3846 | 63275573 |
Initial insomnia | 17.17 | 10.16 | 52 | 209551 | 6105 | 63273314 |
Calculus urinary | 17.15 | 10.16 | 22 | 209581 | 1362 | 63278057 |
Hyperphagia | 17.09 | 10.16 | 25 | 209578 | 1754 | 63277665 |
Alcohol poisoning | 17.05 | 10.16 | 26 | 209577 | 1893 | 63277526 |
Pulmonary hypertension | 16.99 | 10.16 | 64 | 209539 | 37059 | 63242360 |
Breast cancer stage II | 16.94 | 10.16 | 4 | 209599 | 8732 | 63270687 |
Areflexia | 16.92 | 10.16 | 34 | 209569 | 3084 | 63276335 |
Suspected product quality issue | 16.74 | 10.16 | 10 | 209593 | 215 | 63279204 |
Cognitive disorder | 16.68 | 10.16 | 268 | 209335 | 55547 | 63223872 |
Thrombotic microangiopathy | 16.63 | 10.16 | 7 | 209596 | 10554 | 63268865 |
Cyanosis | 16.46 | 10.16 | 104 | 209499 | 16831 | 63262588 |
Jaundice | 16.46 | 10.16 | 46 | 209557 | 29205 | 63250214 |
Flat affect | 16.34 | 10.16 | 22 | 209581 | 1428 | 63277991 |
Oculogyric crisis | 16.26 | 10.16 | 24 | 209579 | 1697 | 63277722 |
Cytokine release syndrome | 16.23 | 10.16 | 14 | 209589 | 14300 | 63265119 |
Encephalopathy | 16.22 | 10.16 | 197 | 209406 | 38423 | 63240996 |
Accidental overdose | 16.19 | 10.16 | 132 | 209471 | 23177 | 63256242 |
Blood growth hormone increased | 16.19 | 10.16 | 13 | 209590 | 457 | 63278962 |
Compulsive shopping | 16.17 | 10.16 | 16 | 209587 | 743 | 63278676 |
Upper respiratory tract infection | 16.13 | 10.16 | 183 | 209420 | 81864 | 63197555 |
Abdominal pain upper | 16.12 | 10.16 | 539 | 209064 | 205905 | 63073514 |
Full blood count decreased | 16.12 | 10.16 | 39 | 209564 | 25985 | 63253434 |
Focal dyscognitive seizures | 16.03 | 10.16 | 32 | 209571 | 2889 | 63276530 |
Pneumonitis | 15.94 | 10.16 | 61 | 209542 | 35161 | 63244258 |
Neuropsychiatric symptoms | 15.92 | 10.16 | 16 | 209587 | 757 | 63278662 |
Visual impairment | 15.89 | 10.16 | 378 | 209225 | 84068 | 63195351 |
Cardiac murmur | 15.82 | 10.16 | 92 | 209511 | 14460 | 63264959 |
Stoma site erythema | 15.73 | 10.16 | 20 | 209583 | 1227 | 63278192 |
Impulse-control disorder | 15.63 | 10.16 | 16 | 209587 | 774 | 63278645 |
Mitral valve thickening | 15.60 | 10.16 | 5 | 209598 | 20 | 63279399 |
Sensitivity to weather change | 15.60 | 10.16 | 56 | 209547 | 7181 | 63272238 |
Epistaxis | 15.58 | 10.16 | 159 | 209444 | 72566 | 63206853 |
Increased appetite | 15.49 | 10.16 | 68 | 209535 | 9562 | 63269857 |
Blood pressure decreased | 15.43 | 10.16 | 301 | 209302 | 64721 | 63214698 |
Haemoglobin decreased | 15.41 | 10.16 | 364 | 209239 | 145121 | 63134298 |
Lip dry | 15.38 | 10.16 | 17 | 209586 | 15453 | 63263966 |
Torticollis | 15.37 | 10.16 | 25 | 209578 | 1924 | 63277495 |
Cerebral atrophy | 15.29 | 10.16 | 44 | 209559 | 5022 | 63274397 |
Clumsiness | 15.24 | 10.16 | 26 | 209577 | 2081 | 63277338 |
Peripheral pulse decreased | 15.17 | 10.16 | 6 | 209597 | 49 | 63279370 |
Feelings of worthlessness | 15.11 | 10.16 | 11 | 209592 | 333 | 63279086 |
Anhedonia | 15.08 | 10.16 | 74 | 209529 | 10900 | 63268519 |
Myopathy | 15.05 | 10.16 | 75 | 209528 | 11116 | 63268303 |
Monocyte count abnormal | 15.05 | 10.16 | 9 | 209594 | 194 | 63279225 |
Headache | 14.93 | 10.16 | 2344 | 207259 | 630897 | 62648522 |
Shock haemorrhagic | 14.89 | 10.16 | 7 | 209596 | 9888 | 63269531 |
Congenital jaw malformation | 14.87 | 10.16 | 5 | 209598 | 24 | 63279395 |
Accidental exposure to product by child | 14.84 | 10.16 | 19 | 209584 | 1174 | 63278245 |
Disseminated intravascular coagulation | 14.83 | 10.16 | 25 | 209578 | 19026 | 63260393 |
Enthesopathy | 14.75 | 10.16 | 5 | 209598 | 8609 | 63270810 |
Fluid retention | 14.72 | 10.16 | 126 | 209477 | 59560 | 63219859 |
Diplopia | 14.70 | 10.16 | 131 | 209472 | 23597 | 63255822 |
Distractibility | 14.70 | 10.16 | 12 | 209591 | 432 | 63278987 |
Injection site pruritus | 14.65 | 10.16 | 88 | 209515 | 45028 | 63234391 |
Narcotic bowel syndrome | 14.61 | 10.16 | 8 | 209595 | 145 | 63279274 |
Abdominal pain | 14.58 | 10.16 | 806 | 208797 | 292650 | 62986769 |
Infantile spasms | 14.57 | 10.16 | 9 | 209594 | 206 | 63279213 |
Cast application | 14.55 | 10.16 | 5 | 209598 | 26 | 63279393 |
Homicidal ideation | 14.53 | 10.16 | 23 | 209580 | 1729 | 63277690 |
Feeling drunk | 14.51 | 10.16 | 38 | 209565 | 4104 | 63275315 |
Nail disorder | 14.43 | 10.16 | 13 | 209590 | 13002 | 63266417 |
Generalised anxiety disorder | 14.22 | 10.16 | 25 | 209578 | 2049 | 63277370 |
Metastases to liver | 14.19 | 10.16 | 36 | 209567 | 23603 | 63255816 |
Myocardial infarction | 14.18 | 10.16 | 238 | 209365 | 99655 | 63179764 |
Hyperbilirubinaemia | 14.18 | 10.16 | 10 | 209593 | 11304 | 63268115 |
Drug screen false positive | 14.14 | 10.16 | 16 | 209587 | 868 | 63278551 |
Grip strength decreased | 14.12 | 10.16 | 33 | 209570 | 22254 | 63257165 |
Electrocardiogram QRS complex shortened | 14.12 | 10.16 | 12 | 209591 | 457 | 63278962 |
Liver function test abnormal | 14.10 | 10.16 | 97 | 209506 | 48084 | 63231335 |
Intrusive thoughts | 14.08 | 10.16 | 9 | 209594 | 219 | 63279200 |
Piloerection | 14.01 | 10.16 | 11 | 209592 | 374 | 63279045 |
Pupil fixed | 13.99 | 10.16 | 23 | 209580 | 1786 | 63277633 |
Sternal fracture | 13.97 | 10.16 | 26 | 209577 | 2228 | 63277191 |
Lip and/or oral cavity cancer | 13.94 | 10.16 | 16 | 209587 | 882 | 63278537 |
Autoimmune disorder | 13.88 | 10.16 | 22 | 209581 | 17155 | 63262264 |
Pre-existing condition improved | 13.87 | 10.16 | 59 | 209544 | 8185 | 63271234 |
Subarachnoid haemorrhage | 13.86 | 10.16 | 16 | 209587 | 14267 | 63265152 |
Drop attacks | 13.84 | 10.16 | 14 | 209589 | 668 | 63278751 |
Tubulointerstitial nephritis | 13.83 | 10.16 | 28 | 209575 | 19875 | 63259544 |
Hallucination, visual | 13.79 | 10.16 | 110 | 209493 | 19188 | 63260231 |
Deformity | 13.77 | 10.16 | 11 | 209592 | 11673 | 63267746 |
Hypotonia | 13.77 | 10.16 | 64 | 209539 | 9221 | 63270198 |
Road traffic accident | 13.75 | 10.16 | 183 | 209420 | 36449 | 63242970 |
Confusional state | 13.73 | 10.16 | 931 | 208672 | 235449 | 63043970 |
Incision site haemorrhage | 13.72 | 10.16 | 13 | 209590 | 572 | 63278847 |
Gaze palsy | 13.70 | 10.16 | 20 | 209583 | 1400 | 63278019 |
Breast cancer stage I | 13.67 | 10.16 | 3 | 209600 | 6886 | 63272533 |
Pericardial effusion | 13.64 | 10.16 | 52 | 209551 | 30006 | 63249413 |
Affective disorder | 13.62 | 10.16 | 48 | 209555 | 6098 | 63273321 |
Hypokalaemia | 13.56 | 10.16 | 251 | 209352 | 103553 | 63175866 |
Wrist fracture | 13.56 | 10.16 | 84 | 209519 | 13503 | 63265916 |
Haematotoxicity | 13.55 | 10.16 | 7 | 209596 | 9369 | 63270050 |
Weight decreased | 13.51 | 10.16 | 1075 | 208528 | 275723 | 63003696 |
Circulatory collapse | 13.49 | 10.16 | 33 | 209570 | 21905 | 63257514 |
Temperature intolerance | 13.45 | 10.16 | 62 | 209541 | 8902 | 63270517 |
Sudden unexplained death in epilepsy | 13.45 | 10.16 | 10 | 209593 | 313 | 63279106 |
Right ventricular systolic pressure decreased | 13.43 | 10.16 | 5 | 209598 | 34 | 63279385 |
Rapid eye movement sleep behaviour disorder | 13.37 | 10.16 | 10 | 209593 | 316 | 63279103 |
Poor quality sleep | 13.37 | 10.16 | 112 | 209491 | 19823 | 63259596 |
Hyperkeratosis | 13.34 | 10.16 | 47 | 209556 | 5971 | 63273448 |
Incision site erythema | 13.33 | 10.16 | 12 | 209591 | 494 | 63278925 |
Colitis ulcerative | 13.27 | 10.16 | 43 | 209560 | 26048 | 63253371 |
Onychophagia | 13.22 | 10.16 | 6 | 209597 | 71 | 63279348 |
Dysphemia | 13.14 | 10.16 | 28 | 209575 | 2647 | 63276772 |
Aerophagia | 13.12 | 10.16 | 4 | 209599 | 13 | 63279406 |
Nephrogenic diabetes insipidus | 13.09 | 10.16 | 16 | 209587 | 943 | 63278476 |
Barotrauma | 13.07 | 10.16 | 8 | 209595 | 180 | 63279239 |
Parkinsonian gait | 13.07 | 10.16 | 12 | 209591 | 507 | 63278912 |
Liver disorder | 12.94 | 10.16 | 114 | 209489 | 53573 | 63225846 |
Bronchial wall thickening | 12.88 | 10.16 | 20 | 209583 | 1479 | 63277940 |
Abscess | 12.86 | 10.16 | 22 | 209581 | 16646 | 63262773 |
Hypertonia | 12.78 | 10.16 | 39 | 209564 | 4598 | 63274821 |
Cushingoid | 12.77 | 10.16 | 6 | 209597 | 8479 | 63270940 |
Transfusion | 12.77 | 10.16 | 19 | 209584 | 15198 | 63264221 |
Femur fracture | 12.75 | 10.16 | 83 | 209520 | 41673 | 63237746 |
Urticaria thermal | 12.74 | 10.16 | 11 | 209592 | 428 | 63278991 |
Sensory disturbance | 12.70 | 10.16 | 83 | 209520 | 13589 | 63265830 |
Eye pain | 12.65 | 10.16 | 169 | 209434 | 33685 | 63245734 |
Hyperacusis | 12.63 | 10.16 | 24 | 209579 | 2089 | 63277330 |
Asphyxia | 12.62 | 10.16 | 47 | 209556 | 6134 | 63273285 |
Rib fracture | 12.61 | 10.16 | 122 | 209481 | 22475 | 63256944 |
Aplastic anaemia | 12.61 | 10.16 | 8 | 209595 | 9561 | 63269858 |
Fear of injection | 12.54 | 10.16 | 4 | 209599 | 7160 | 63272259 |
Bone density decreased | 12.50 | 10.16 | 18 | 209585 | 14594 | 63264825 |
Psychiatric decompensation | 12.47 | 10.16 | 19 | 209584 | 1382 | 63278037 |
Haemangioma congenital | 12.47 | 10.16 | 11 | 209592 | 441 | 63278978 |
Hypercholesterolaemia | 12.42 | 10.16 | 33 | 209570 | 21301 | 63258118 |
Acute generalised exanthematous pustulosis | 12.41 | 10.16 | 11 | 209592 | 11088 | 63268331 |
Gastrointestinal procedural complication | 12.37 | 10.16 | 8 | 209595 | 199 | 63279220 |
Delirium | 12.34 | 10.16 | 235 | 209368 | 50306 | 63229113 |
Pulmonary toxicity | 12.32 | 10.16 | 8 | 209595 | 9447 | 63269972 |
Osteoarthritis | 12.31 | 10.16 | 231 | 209372 | 95112 | 63184307 |
Hyperkinesia | 12.29 | 10.16 | 21 | 209582 | 1683 | 63277736 |
Pathogen resistance | 12.27 | 10.16 | 3 | 209600 | 6395 | 63273024 |
Hormone level abnormal | 12.21 | 10.16 | 26 | 209577 | 2457 | 63276962 |
Red blood cells urine | 12.20 | 10.16 | 12 | 209591 | 553 | 63278866 |
Tonic clonic movements | 12.13 | 10.16 | 19 | 209584 | 1416 | 63278003 |
Family stress | 12.11 | 10.16 | 13 | 209590 | 665 | 63278754 |
Oculocephalogyric reflex absent | 12.08 | 10.16 | 3 | 209600 | 3 | 63279416 |
Cholestasis | 12.05 | 10.16 | 53 | 209550 | 29381 | 63250038 |
Colitis microscopic | 12.04 | 10.16 | 8 | 209595 | 9331 | 63270088 |
Suspiciousness | 12.04 | 10.16 | 10 | 209593 | 369 | 63279050 |
Flight of ideas | 12.02 | 10.16 | 11 | 209592 | 463 | 63278956 |
Ulcer | 11.95 | 10.16 | 45 | 209558 | 26062 | 63253357 |
Drug level above therapeutic | 11.95 | 10.16 | 39 | 209564 | 4766 | 63274653 |
Fever neonatal | 11.93 | 10.16 | 4 | 209599 | 19 | 63279400 |
Behaviour disorder | 11.88 | 10.16 | 30 | 209573 | 3169 | 63276250 |
Joint destruction | 11.86 | 10.16 | 3 | 209600 | 6249 | 63273170 |
Nasal disorder | 11.85 | 10.16 | 28 | 209575 | 2836 | 63276583 |
Fractured coccyx | 11.83 | 10.16 | 16 | 209587 | 1043 | 63278376 |
Stupor | 11.83 | 10.16 | 36 | 209567 | 4239 | 63275180 |
Eating disorder | 11.79 | 10.16 | 105 | 209498 | 18911 | 63260508 |
Therapeutic response decreased | 11.79 | 10.16 | 138 | 209465 | 61387 | 63218032 |
Product quality issue | 11.78 | 10.16 | 175 | 209428 | 35690 | 63243729 |
Sensorimotor disorder | 11.78 | 10.16 | 11 | 209592 | 475 | 63278944 |
Adrenal insufficiency | 11.78 | 10.16 | 26 | 209577 | 17889 | 63261530 |
Solar lentigo | 11.75 | 10.16 | 14 | 209589 | 803 | 63278616 |
Hepatic cirrhosis | 11.74 | 10.16 | 42 | 209561 | 24692 | 63254727 |
Illusion | 11.70 | 10.16 | 16 | 209587 | 1054 | 63278365 |
Bronchopulmonary aspergillosis | 11.68 | 10.16 | 7 | 209596 | 8628 | 63270791 |
Band neutrophil count increased | 11.68 | 10.16 | 10 | 209593 | 385 | 63279034 |
Brain death | 11.66 | 10.16 | 31 | 209572 | 3379 | 63276040 |
Metastases to lung | 11.62 | 10.16 | 15 | 209588 | 12735 | 63266684 |
Bradycardia neonatal | 11.59 | 10.16 | 15 | 209588 | 937 | 63278482 |
Lower limb fracture | 11.58 | 10.16 | 41 | 209562 | 24180 | 63255239 |
Drug eruption | 11.55 | 10.16 | 52 | 209551 | 28642 | 63250777 |
Adjustment disorder with depressed mood | 11.54 | 10.16 | 10 | 209593 | 10194 | 63269225 |
Antinuclear antibody positive | 11.52 | 10.16 | 6 | 209597 | 7993 | 63271426 |
Oliguria | 11.46 | 10.16 | 8 | 209595 | 9093 | 63270326 |
Toxicologic test abnormal | 11.45 | 10.16 | 13 | 209590 | 708 | 63278711 |
Blood bilirubin increased | 11.35 | 10.16 | 179 | 209424 | 36961 | 63242458 |
Heat stroke | 11.33 | 10.16 | 14 | 209589 | 834 | 63278585 |
Acute myocardial infarction | 11.32 | 10.16 | 61 | 209542 | 32063 | 63247356 |
Accidental death | 11.27 | 10.16 | 22 | 209581 | 1954 | 63277465 |
Sarcoidosis | 11.24 | 10.16 | 50 | 209553 | 7072 | 63272347 |
Decreased activity | 11.23 | 10.16 | 46 | 209557 | 6274 | 63273145 |
Orthostatic tremor | 11.22 | 10.16 | 3 | 209600 | 5 | 63279414 |
Juvenile myoclonic epilepsy | 11.16 | 10.16 | 4 | 209599 | 24 | 63279395 |
Skin necrosis | 11.15 | 10.16 | 18 | 209585 | 13932 | 63265487 |
Cataplexy | 11.13 | 10.16 | 17 | 209586 | 1239 | 63278180 |
Hypersexuality | 11.11 | 10.16 | 11 | 209592 | 511 | 63278908 |
Sinus disorder | 11.09 | 10.16 | 127 | 209476 | 24426 | 63254993 |
Social avoidant behaviour | 11.08 | 10.16 | 28 | 209575 | 2960 | 63276459 |
Retinal detachment | 11.06 | 10.16 | 3 | 209600 | 5966 | 63273453 |
Sleep disorder | 11.06 | 10.16 | 350 | 209253 | 81216 | 63198203 |
Cholecystitis chronic | 10.94 | 10.16 | 65 | 209538 | 10296 | 63269123 |
Neoplasm malignant | 10.92 | 10.16 | 56 | 209547 | 29805 | 63249614 |
Temporomandibular joint syndrome | 10.91 | 10.16 | 34 | 209569 | 4055 | 63275364 |
Chronic papillomatous dermatitis | 10.88 | 10.16 | 5 | 209598 | 61 | 63279358 |
Automatism | 10.88 | 10.16 | 5 | 209598 | 61 | 63279358 |
Diabetes mellitus | 10.86 | 10.16 | 251 | 209352 | 55559 | 63223860 |
Administration site erythema | 10.83 | 10.16 | 13 | 209590 | 752 | 63278667 |
Cardiac infection | 10.80 | 10.16 | 11 | 209592 | 529 | 63278890 |
Polydipsia | 10.80 | 10.16 | 31 | 209572 | 3533 | 63275886 |
Panniculitis | 10.79 | 10.16 | 13 | 209590 | 11372 | 63268047 |
Parasomnia | 10.73 | 10.16 | 11 | 209592 | 533 | 63278886 |
Device difficult to use | 10.71 | 10.16 | 16 | 209587 | 12780 | 63266639 |
Pancreatolithiasis | 10.69 | 10.16 | 8 | 209595 | 253 | 63279166 |
Urine oxalate increased | 10.66 | 10.16 | 8 | 209595 | 254 | 63279165 |
Fibromyalgia | 10.62 | 10.16 | 344 | 209259 | 80076 | 63199343 |
Sciatica | 10.60 | 10.16 | 68 | 209535 | 34256 | 63245163 |
Hypoacusis | 10.50 | 10.16 | 124 | 209479 | 24027 | 63255392 |
Device use error | 10.48 | 10.16 | 3 | 209600 | 5758 | 63273661 |
Body height increased | 10.47 | 10.16 | 5 | 209598 | 67 | 63279352 |
Rash maculo-papular | 10.47 | 10.16 | 62 | 209541 | 31834 | 63247585 |
Therapeutic product effect prolonged | 10.43 | 10.16 | 9 | 209594 | 350 | 63279069 |
Klebsiella test positive | 10.43 | 10.16 | 16 | 209587 | 1171 | 63278248 |
Metastases to central nervous system | 10.39 | 10.16 | 17 | 209586 | 13088 | 63266331 |
Electrocardiogram QRS complex prolonged | 10.38 | 10.16 | 43 | 209560 | 5895 | 63273524 |
Breast cancer female | 10.37 | 10.16 | 18 | 209585 | 13541 | 63265878 |
Coagulopathy | 10.35 | 10.16 | 34 | 209569 | 20510 | 63258909 |
Aspergillus infection | 10.34 | 10.16 | 7 | 209596 | 8086 | 63271333 |
Treatment noncompliance | 10.33 | 10.16 | 177 | 209426 | 37148 | 63242271 |
Abdominal distension | 10.30 | 10.16 | 366 | 209237 | 86249 | 63193170 |
Localised infection | 10.30 | 10.16 | 58 | 209545 | 30152 | 63249267 |
Perfume sensitivity | 10.30 | 10.16 | 13 | 209590 | 792 | 63278627 |
Blood potassium increased | 10.29 | 10.16 | 99 | 209504 | 18210 | 63261209 |
Illness | 10.29 | 10.16 | 223 | 209380 | 48836 | 63230583 |
Ischaemic stroke | 10.28 | 10.16 | 28 | 209575 | 17929 | 63261490 |
Large intestine operation | 10.28 | 10.16 | 3 | 209600 | 8 | 63279411 |
Immunoglobulins increased | 10.28 | 10.16 | 10 | 209593 | 455 | 63278964 |
Apnoea | 10.26 | 10.16 | 53 | 209550 | 7969 | 63271450 |
Polyarthritis | 10.25 | 10.16 | 11 | 209592 | 10135 | 63269284 |
Multiple organ dysfunction syndrome | 10.22 | 10.16 | 129 | 209474 | 56623 | 63222796 |
Congenital knee deformity | 10.21 | 10.16 | 5 | 209598 | 71 | 63279348 |
Neurological symptom | 10.21 | 10.16 | 42 | 209561 | 5741 | 63273678 |
Stoma site infection | 10.21 | 10.16 | 13 | 209590 | 799 | 63278620 |
Myelocyte count increased | 10.20 | 10.16 | 9 | 209594 | 361 | 63279058 |
Rectal haemorrhage | 10.17 | 10.16 | 108 | 209495 | 48922 | 63230497 |
Conjunctivitis allergic | 10.17 | 10.16 | 14 | 209589 | 928 | 63278491 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug abuse | 1467.64 | 10.72 | 1691 | 109963 | 97405 | 34747872 |
Depression | 977.42 | 10.72 | 1368 | 110286 | 95730 | 34749547 |
Completed suicide | 875.33 | 10.72 | 1306 | 110348 | 96862 | 34748415 |
Toxicity to various agents | 696.02 | 10.72 | 1789 | 109865 | 198573 | 34646704 |
Drug interaction | 440.04 | 10.72 | 1650 | 110004 | 224296 | 34620981 |
Somnolence | 434.06 | 10.72 | 1039 | 110615 | 110077 | 34735200 |
Coma | 365.83 | 10.72 | 579 | 111075 | 45099 | 34800178 |
Sopor | 363.25 | 10.72 | 305 | 111349 | 11831 | 34833446 |
Overdose | 361.40 | 10.72 | 857 | 110797 | 90202 | 34755075 |
Suicidal ideation | 311.10 | 10.72 | 503 | 111151 | 39885 | 34805392 |
Intentional overdose | 297.78 | 10.72 | 515 | 111139 | 43159 | 34802118 |
Miosis | 281.98 | 10.72 | 238 | 111416 | 9297 | 34835980 |
Neuroleptic malignant syndrome | 272.72 | 10.72 | 311 | 111343 | 17623 | 34827654 |
Aggression | 270.26 | 10.72 | 463 | 111191 | 38501 | 34806776 |
Psychiatric decompensation | 261.48 | 10.72 | 145 | 111509 | 2792 | 34842485 |
Anxiety | 259.60 | 10.72 | 802 | 110852 | 98626 | 34746651 |
Psychotic disorder | 259.44 | 10.72 | 354 | 111300 | 24098 | 34821179 |
Drug dependence | 259.07 | 10.72 | 352 | 111302 | 23865 | 34821412 |
Suicide attempt | 257.21 | 10.72 | 454 | 111200 | 38662 | 34806615 |
Agitation | 247.04 | 10.72 | 558 | 111096 | 56841 | 34788436 |
Seizure | 237.74 | 10.72 | 806 | 110848 | 104051 | 34741226 |
Poisoning | 235.02 | 10.72 | 240 | 111414 | 11986 | 34833291 |
Respiratory arrest | 234.88 | 10.72 | 363 | 111291 | 27680 | 34817597 |
Substance abuse | 206.18 | 10.72 | 181 | 111473 | 7460 | 34837817 |
Cardio-respiratory arrest | 196.49 | 10.72 | 499 | 111155 | 54774 | 34790503 |
Febrile neutropenia | 191.60 | 10.72 | 99 | 111555 | 136750 | 34708527 |
Altered state of consciousness | 189.83 | 10.72 | 295 | 111359 | 22598 | 34822679 |
Intentional product misuse | 188.01 | 10.72 | 436 | 111218 | 45175 | 34800102 |
Paranoia | 181.30 | 10.72 | 208 | 111446 | 11860 | 34833417 |
Drug withdrawal syndrome | 176.33 | 10.72 | 264 | 111390 | 19570 | 34825707 |
Sedation | 176.00 | 10.72 | 272 | 111382 | 20734 | 34824543 |
Anaemia | 174.10 | 10.72 | 299 | 111355 | 233036 | 34612241 |
Abnormal behaviour | 172.15 | 10.72 | 296 | 111358 | 24673 | 34820604 |
Intentional self-injury | 168.69 | 10.72 | 214 | 111440 | 13557 | 34831720 |
Depression suicidal | 168.22 | 10.72 | 103 | 111551 | 2402 | 34842875 |
Tearfulness | 164.78 | 10.72 | 104 | 111550 | 2563 | 34842714 |
Depressed level of consciousness | 164.07 | 10.72 | 398 | 111256 | 42443 | 34802834 |
Psychomotor skills impaired | 157.41 | 10.72 | 117 | 111537 | 3789 | 34841488 |
Status epilepticus | 156.06 | 10.72 | 197 | 111457 | 12417 | 34832860 |
Depressive symptom | 148.51 | 10.72 | 100 | 111554 | 2759 | 34842518 |
Acute kidney injury | 147.81 | 10.72 | 491 | 111163 | 304497 | 34540780 |
Dyspnoea | 143.53 | 10.72 | 668 | 110986 | 376114 | 34469163 |
Dyskinesia | 130.63 | 10.72 | 247 | 111407 | 22166 | 34823111 |
Loss of personal independence in daily activities | 127.83 | 10.72 | 309 | 111345 | 32870 | 34812407 |
Panic attack | 119.37 | 10.72 | 149 | 111505 | 9283 | 34835994 |
Diarrhoea | 119.25 | 10.72 | 744 | 110910 | 389168 | 34456109 |
Hallucination | 117.53 | 10.72 | 397 | 111257 | 51101 | 34794176 |
Interstitial lung disease | 114.82 | 10.72 | 33 | 111621 | 65249 | 34780028 |
Malignant neoplasm progression | 114.08 | 10.72 | 70 | 111584 | 87976 | 34757301 |
Pancytopenia | 112.13 | 10.72 | 84 | 111570 | 95073 | 34750204 |
Speech disorder | 111.84 | 10.72 | 251 | 111403 | 25435 | 34819842 |
Insomnia | 108.66 | 10.72 | 634 | 111020 | 103273 | 34742004 |
Thrombocytopenia | 105.93 | 10.72 | 212 | 111442 | 156035 | 34689242 |
Mydriasis | 105.78 | 10.72 | 123 | 111531 | 7114 | 34838163 |
Bradykinesia | 104.58 | 10.72 | 92 | 111562 | 3801 | 34841476 |
Salivary hypersecretion | 102.19 | 10.72 | 132 | 111522 | 8512 | 34836765 |
Disease progression | 100.77 | 10.72 | 118 | 111536 | 107959 | 34737318 |
Sepsis | 100.55 | 10.72 | 241 | 111413 | 166320 | 34678957 |
On and off phenomenon | 96.62 | 10.72 | 73 | 111581 | 2424 | 34842853 |
Ataxia | 96.48 | 10.72 | 165 | 111489 | 13688 | 34831589 |
Parkinsonism | 94.22 | 10.72 | 123 | 111531 | 8015 | 34837262 |
Cardiac arrest | 93.66 | 10.72 | 576 | 111078 | 95583 | 34749694 |
Pneumonia aspiration | 91.19 | 10.72 | 318 | 111336 | 41585 | 34803692 |
Dystonia | 88.83 | 10.72 | 139 | 111515 | 10706 | 34834571 |
Delusion | 88.66 | 10.72 | 151 | 111503 | 12484 | 34832793 |
Pneumonia | 87.96 | 10.72 | 739 | 110915 | 361888 | 34483389 |
Muscle rigidity | 86.41 | 10.72 | 135 | 111519 | 10383 | 34834894 |
Psychomotor retardation | 85.76 | 10.72 | 80 | 111574 | 3570 | 34841707 |
Atrial fibrillation | 85.57 | 10.72 | 163 | 111491 | 122230 | 34723047 |
Bradyphrenia | 84.68 | 10.72 | 90 | 111564 | 4708 | 34840569 |
Bradypnoea | 84.42 | 10.72 | 71 | 111583 | 2758 | 34842519 |
Restlessness | 83.25 | 10.72 | 223 | 111431 | 25259 | 34820018 |
Platelet count decreased | 82.33 | 10.72 | 161 | 111493 | 119556 | 34725721 |
Psychomotor hyperactivity | 81.15 | 10.72 | 125 | 111529 | 9497 | 34835780 |
Hallucination, auditory | 80.44 | 10.72 | 140 | 111514 | 11777 | 34833500 |
Rash | 80.41 | 10.72 | 402 | 111252 | 222350 | 34622927 |
Pyrexia | 80.11 | 10.72 | 680 | 110974 | 332333 | 34512944 |
Epilepsy | 77.29 | 10.72 | 195 | 111459 | 21300 | 34823977 |
Serotonin syndrome | 77.14 | 10.72 | 186 | 111468 | 19747 | 34825530 |
Thinking abnormal | 76.15 | 10.72 | 96 | 111558 | 6041 | 34839236 |
Drug withdrawal convulsions | 75.49 | 10.72 | 47 | 111607 | 1130 | 34844147 |
Cardiac failure | 75.40 | 10.72 | 109 | 111545 | 91139 | 34754138 |
Prescribed overdose | 74.38 | 10.72 | 127 | 111527 | 10520 | 34834757 |
Victim of crime | 73.68 | 10.72 | 32 | 111622 | 351 | 34844926 |
Renal failure | 73.25 | 10.72 | 196 | 111458 | 130361 | 34714916 |
Granulocytopenia | 72.54 | 10.72 | 97 | 111557 | 6470 | 34838807 |
Device dislocation | 71.65 | 10.72 | 94 | 111560 | 6155 | 34839122 |
General physical health deterioration | 71.63 | 10.72 | 193 | 111461 | 128076 | 34717201 |
Tremor | 71.35 | 10.72 | 480 | 111174 | 82107 | 34763170 |
Mental impairment | 70.64 | 10.72 | 122 | 111532 | 10200 | 34835077 |
Neutropenia | 70.60 | 10.72 | 260 | 111394 | 156518 | 34688759 |
Irritability | 69.77 | 10.72 | 205 | 111449 | 24485 | 34820792 |
Renal impairment | 69.49 | 10.72 | 122 | 111532 | 94391 | 34750886 |
Generalised tonic-clonic seizure | 67.85 | 10.72 | 184 | 111470 | 20990 | 34824287 |
Myocardial infarction | 66.25 | 10.72 | 184 | 111470 | 120901 | 34724376 |
Drug use disorder | 65.93 | 10.72 | 74 | 111580 | 4117 | 34841160 |
Cognitive disorder | 65.25 | 10.72 | 221 | 111433 | 28472 | 34816805 |
Hyperkalaemia | 64.39 | 10.72 | 76 | 111578 | 69313 | 34775964 |
Stoma site discharge | 64.37 | 10.72 | 43 | 111611 | 1170 | 34844107 |
Gastrointestinal haemorrhage | 64.33 | 10.72 | 115 | 111539 | 88362 | 34756915 |
Catatonia | 62.97 | 10.72 | 79 | 111575 | 4946 | 34840331 |
Pleural effusion | 62.02 | 10.72 | 103 | 111551 | 81443 | 34763834 |
Akathisia | 61.02 | 10.72 | 100 | 111554 | 8009 | 34837268 |
Device interaction | 60.93 | 10.72 | 32 | 111622 | 550 | 34844727 |
Posture abnormal | 60.32 | 10.72 | 53 | 111601 | 2186 | 34843091 |
Anger | 59.60 | 10.72 | 123 | 111531 | 11761 | 34833516 |
Disturbance in attention | 59.14 | 10.72 | 200 | 111454 | 25745 | 34819532 |
Myoclonic epilepsy | 58.97 | 10.72 | 40 | 111614 | 1117 | 34844160 |
Ascites | 58.95 | 10.72 | 38 | 111616 | 46533 | 34798744 |
COVID-19 | 58.93 | 10.72 | 98 | 111556 | 77452 | 34767825 |
Memory impairment | 58.68 | 10.72 | 284 | 111370 | 43034 | 34802243 |
Confusional state | 58.20 | 10.72 | 710 | 110944 | 143450 | 34701827 |
Joint swelling | 57.29 | 10.72 | 64 | 111590 | 59826 | 34785451 |
Multiple-drug resistance | 55.76 | 10.72 | 76 | 111578 | 5163 | 34840114 |
Respiratory depression | 54.91 | 10.72 | 144 | 111510 | 16101 | 34829176 |
Cardiac failure congestive | 54.65 | 10.72 | 115 | 111539 | 83155 | 34762122 |
Unresponsive to stimuli | 53.83 | 10.72 | 202 | 111452 | 27367 | 34817910 |
Dysarthria | 53.74 | 10.72 | 237 | 111417 | 34545 | 34810732 |
Gait disturbance | 52.32 | 10.72 | 457 | 111197 | 84683 | 34760594 |
Tardive dyskinesia | 51.34 | 10.72 | 77 | 111577 | 5713 | 34839564 |
Middle insomnia | 51.34 | 10.72 | 84 | 111570 | 6718 | 34838559 |
Haemoglobin decreased | 51.30 | 10.72 | 205 | 111449 | 120567 | 34724710 |
Drooling | 50.29 | 10.72 | 58 | 111596 | 3324 | 34841953 |
Mucosal inflammation | 49.58 | 10.72 | 31 | 111623 | 38591 | 34806686 |
Mental disorder | 49.56 | 10.72 | 133 | 111521 | 15076 | 34830201 |
Mania | 49.54 | 10.72 | 100 | 111554 | 9411 | 34835866 |
Withdrawal syndrome | 49.02 | 10.72 | 117 | 111537 | 12338 | 34832939 |
Fall | 49.02 | 10.72 | 915 | 110739 | 201970 | 34643307 |
Drug ineffective | 48.74 | 10.72 | 1849 | 109805 | 454902 | 34390375 |
Dyspnoea exertional | 48.68 | 10.72 | 40 | 111614 | 43239 | 34802038 |
Hallucination, visual | 48.63 | 10.72 | 146 | 111508 | 17645 | 34827632 |
Nervousness | 48.10 | 10.72 | 117 | 111537 | 12489 | 34832788 |
Disorientation | 47.43 | 10.72 | 221 | 111433 | 32967 | 34812310 |
Stoma site erythema | 47.11 | 10.72 | 31 | 111623 | 822 | 34844455 |
Stomatitis | 46.94 | 10.72 | 40 | 111614 | 42474 | 34802803 |
Nausea | 46.53 | 10.72 | 785 | 110869 | 339123 | 34506154 |
Myoclonus | 46.22 | 10.72 | 127 | 111527 | 14598 | 34830679 |
Infusion related reaction | 46.19 | 10.72 | 61 | 111593 | 52996 | 34792281 |
Housebound | 46.16 | 10.72 | 20 | 111634 | 218 | 34845059 |
Behaviour disorder | 45.99 | 10.72 | 67 | 111587 | 4843 | 34840434 |
Hyperprolactinaemia | 45.46 | 10.72 | 39 | 111615 | 1557 | 34843720 |
Freezing phenomenon | 44.70 | 10.72 | 38 | 111616 | 1498 | 34843779 |
Drug abuser | 44.59 | 10.72 | 59 | 111595 | 3895 | 34841382 |
Angioedema | 43.98 | 10.72 | 33 | 111621 | 37341 | 34807936 |
Loss of consciousness | 43.87 | 10.72 | 430 | 111224 | 82237 | 34763040 |
Infection | 43.40 | 10.72 | 147 | 111507 | 90768 | 34754509 |
Urticaria | 42.75 | 10.72 | 84 | 111570 | 62293 | 34782984 |
Acute myocardial infarction | 42.57 | 10.72 | 66 | 111588 | 53653 | 34791624 |
Blood creatinine increased | 42.39 | 10.72 | 158 | 111496 | 94818 | 34750459 |
Crying | 42.37 | 10.72 | 71 | 111583 | 5791 | 34839486 |
Multiple organ dysfunction syndrome | 42.11 | 10.72 | 116 | 111538 | 76450 | 34768827 |
Schizophrenia | 41.48 | 10.72 | 88 | 111566 | 8578 | 34836699 |
Cerebrovascular accident | 41.26 | 10.72 | 136 | 111518 | 84675 | 34760602 |
Colitis | 41.09 | 10.72 | 36 | 111618 | 37714 | 34807563 |
Reduced facial expression | 40.24 | 10.72 | 31 | 111623 | 1060 | 34844217 |
Pruritus | 40.08 | 10.72 | 277 | 111377 | 141704 | 34703573 |
Visceral congestion | 40.01 | 10.72 | 25 | 111629 | 605 | 34844672 |
Abnormal dreams | 39.86 | 10.72 | 80 | 111574 | 7498 | 34837779 |
Screaming | 39.72 | 10.72 | 35 | 111619 | 1449 | 34843828 |
Cerebral haemorrhage | 39.65 | 10.72 | 32 | 111622 | 34905 | 34810372 |
Cytomegalovirus infection | 39.44 | 10.72 | 17 | 111637 | 26118 | 34819159 |
Myelosuppression | 39.33 | 10.72 | 7 | 111647 | 19258 | 34826019 |
Lactic acidosis | 39.27 | 10.72 | 32 | 111622 | 34740 | 34810537 |
Decreased appetite | 38.86 | 10.72 | 342 | 111312 | 166050 | 34679227 |
Pneumocystis jirovecii pneumonia | 38.46 | 10.72 | 8 | 111646 | 19702 | 34825575 |
Bone marrow failure | 38.22 | 10.72 | 23 | 111631 | 29230 | 34816047 |
Anticonvulsant drug level above therapeutic | 38.19 | 10.72 | 25 | 111629 | 657 | 34844620 |
Erythema | 38.13 | 10.72 | 150 | 111504 | 88630 | 34756647 |
Accidental death | 38.01 | 10.72 | 43 | 111611 | 2413 | 34842864 |
Dystonic tremor | 37.94 | 10.72 | 17 | 111637 | 202 | 34845075 |
Blood creatine phosphokinase increased | 37.68 | 10.72 | 259 | 111395 | 44598 | 34800679 |
Prostate cancer | 37.23 | 10.72 | 43 | 111611 | 39606 | 34805671 |
Priapism | 36.78 | 10.72 | 61 | 111593 | 4933 | 34840344 |
Partial seizures | 36.22 | 10.72 | 59 | 111595 | 4701 | 34840576 |
Cytokine release syndrome | 35.95 | 10.72 | 14 | 111640 | 22863 | 34822414 |
Melaena | 35.85 | 10.72 | 36 | 111618 | 35344 | 34809933 |
Myelopathy | 35.76 | 10.72 | 42 | 111612 | 2455 | 34842822 |
Contraindicated product administered | 35.70 | 10.72 | 12 | 111642 | 21469 | 34823808 |
Agoraphobia | 35.66 | 10.72 | 17 | 111637 | 235 | 34845042 |
Post-anoxic myoclonus | 35.60 | 10.72 | 9 | 111645 | 11 | 34845266 |
Accidental overdose | 35.59 | 10.72 | 143 | 111511 | 19997 | 34825280 |
Affect lability | 35.58 | 10.72 | 51 | 111603 | 3632 | 34841645 |
Toxicologic test abnormal | 35.15 | 10.72 | 22 | 111632 | 534 | 34844743 |
Dysphoria | 35.11 | 10.72 | 40 | 111614 | 2262 | 34843015 |
Anaphylactic reaction | 34.92 | 10.72 | 31 | 111623 | 32270 | 34813007 |
Drug diversion | 34.68 | 10.72 | 26 | 111628 | 853 | 34844424 |
Oedema peripheral | 34.68 | 10.72 | 232 | 111422 | 119580 | 34725697 |
Drug intolerance | 34.46 | 10.72 | 88 | 111566 | 59482 | 34785795 |
Hyperammonaemia | 34.43 | 10.72 | 68 | 111586 | 6299 | 34838978 |
Arthralgia | 34.41 | 10.72 | 362 | 111292 | 169679 | 34675598 |
Septic shock | 34.38 | 10.72 | 116 | 111538 | 71718 | 34773559 |
Hypertonia | 34.18 | 10.72 | 54 | 111600 | 4192 | 34841085 |
Coronary artery disease | 34.01 | 10.72 | 64 | 111590 | 48241 | 34797036 |
Compartment syndrome | 33.98 | 10.72 | 45 | 111609 | 2973 | 34842304 |
Proteinuria | 33.55 | 10.72 | 9 | 111645 | 18633 | 34826644 |
Encephalitis toxic | 33.51 | 10.72 | 17 | 111637 | 271 | 34845006 |
Hypothermia | 33.04 | 10.72 | 92 | 111562 | 10656 | 34834621 |
Bronchopulmonary aspergillosis | 32.99 | 10.72 | 4 | 111650 | 14655 | 34830622 |
Haematochezia | 32.46 | 10.72 | 62 | 111592 | 46472 | 34798805 |
Neuropathy peripheral | 32.46 | 10.72 | 146 | 111508 | 83117 | 34762160 |
Psychogenic seizure | 32.29 | 10.72 | 18 | 111636 | 350 | 34844927 |
Feeling of despair | 32.25 | 10.72 | 26 | 111628 | 951 | 34844326 |
Plasma cell myeloma | 32.03 | 10.72 | 53 | 111601 | 41984 | 34803293 |
Sleep apnoea syndrome | 31.78 | 10.72 | 139 | 111515 | 20182 | 34825095 |
Product substitution issue | 31.61 | 10.72 | 87 | 111567 | 10008 | 34835269 |
Drug screen positive | 31.54 | 10.72 | 50 | 111604 | 3893 | 34841384 |
Withdrawal arrhythmia | 31.53 | 10.72 | 10 | 111644 | 40 | 34845237 |
Drug hypersensitivity | 31.51 | 10.72 | 141 | 111513 | 80388 | 34764889 |
Illness anxiety disorder | 31.50 | 10.72 | 14 | 111640 | 163 | 34845114 |
Bipolar disorder | 31.41 | 10.72 | 48 | 111606 | 3621 | 34841656 |
Drug level above therapeutic | 31.32 | 10.72 | 52 | 111602 | 4209 | 34841068 |
Haematuria | 31.30 | 10.72 | 71 | 111583 | 49995 | 34795282 |
Thrombosis | 31.19 | 10.72 | 72 | 111582 | 50386 | 34794891 |
Meconium aspiration syndrome | 31.15 | 10.72 | 10 | 111644 | 42 | 34845235 |
Electroencephalogram abnormal | 31.12 | 10.72 | 39 | 111615 | 2439 | 34842838 |
Cough | 31.04 | 10.72 | 318 | 111336 | 149822 | 34695455 |
Depressed mood | 30.88 | 10.72 | 133 | 111521 | 19184 | 34826093 |
Torticollis | 30.45 | 10.72 | 27 | 111627 | 1127 | 34844150 |
Neutropenic sepsis | 30.39 | 10.72 | 4 | 111650 | 13763 | 34831514 |
Accidental poisoning | 30.35 | 10.72 | 23 | 111631 | 767 | 34844510 |
Brain scan abnormal | 30.28 | 10.72 | 24 | 111630 | 856 | 34844421 |
Feeling abnormal | 30.22 | 10.72 | 322 | 111332 | 62913 | 34782364 |
Delirium | 30.12 | 10.72 | 242 | 111412 | 43749 | 34801528 |
Excessive eye blinking | 30.11 | 10.72 | 20 | 111634 | 539 | 34844738 |
Blood creatine phosphokinase | 30.01 | 10.72 | 12 | 111642 | 105 | 34845172 |
Postmortem blood drug level abnormal | 29.95 | 10.72 | 16 | 111638 | 285 | 34844992 |
Myelodysplastic syndrome | 29.78 | 10.72 | 12 | 111642 | 19196 | 34826081 |
Postmortem blood drug level increased | 29.57 | 10.72 | 15 | 111639 | 239 | 34845038 |
Movement disorder | 29.31 | 10.72 | 96 | 111558 | 12152 | 34833125 |
COVID-19 pneumonia | 29.05 | 10.72 | 9 | 111645 | 16958 | 34828319 |
Cerebral infarction | 28.90 | 10.72 | 27 | 111627 | 27428 | 34817849 |
Disinhibition | 28.74 | 10.72 | 43 | 111611 | 3183 | 34842094 |
Poor quality sleep | 28.74 | 10.72 | 74 | 111580 | 8182 | 34837095 |
Panic disorder | 28.53 | 10.72 | 27 | 111627 | 1227 | 34844050 |
Vessel puncture site erythema | 28.50 | 10.72 | 6 | 111648 | 0 | 34845277 |
Cerebral artery thrombosis | 28.41 | 10.72 | 22 | 111632 | 758 | 34844519 |
Drug screen negative | 28.12 | 10.72 | 13 | 111641 | 167 | 34845110 |
Basal cell carcinoma | 27.79 | 10.72 | 14 | 111640 | 19644 | 34825633 |
Developmental delay | 27.65 | 10.72 | 39 | 111615 | 2736 | 34842541 |
Generalised anxiety disorder | 27.63 | 10.72 | 22 | 111632 | 790 | 34844487 |
Balance disorder | 27.49 | 10.72 | 223 | 111431 | 40431 | 34804846 |
Dehydration | 27.38 | 10.72 | 274 | 111380 | 129695 | 34715582 |
Electrocardiogram QRS complex prolonged | 27.35 | 10.72 | 53 | 111601 | 4841 | 34840436 |
Obsessive-compulsive disorder | 27.21 | 10.72 | 57 | 111597 | 5507 | 34839770 |
Red cell distribution width decreased | 27.06 | 10.72 | 13 | 111641 | 183 | 34845094 |
Failure to suspend medication | 26.86 | 10.72 | 17 | 111637 | 421 | 34844856 |
Tubulointerstitial nephritis | 26.81 | 10.72 | 17 | 111637 | 21007 | 34824270 |
Bacteraemia | 26.47 | 10.72 | 15 | 111639 | 19702 | 34825575 |
Choreoathetosis | 26.31 | 10.72 | 24 | 111630 | 1040 | 34844237 |
Hypomagnesaemia | 26.08 | 10.72 | 19 | 111635 | 21832 | 34823445 |
Coordination abnormal | 26.08 | 10.72 | 68 | 111586 | 7576 | 34837701 |
Aspergillus infection | 26.02 | 10.72 | 4 | 111650 | 12250 | 34833027 |
Vomiting | 25.88 | 10.72 | 598 | 111056 | 247023 | 34598254 |
Acute myeloid leukaemia | 25.84 | 10.72 | 13 | 111641 | 18257 | 34827020 |
Brain injury | 25.59 | 10.72 | 59 | 111595 | 6083 | 34839194 |
Peripheral swelling | 25.38 | 10.72 | 142 | 111512 | 76399 | 34768878 |
Tension | 25.37 | 10.72 | 33 | 111621 | 2142 | 34843135 |
Epistaxis | 25.27 | 10.72 | 98 | 111556 | 58153 | 34787124 |
Haemorrhage | 25.23 | 10.72 | 82 | 111572 | 51288 | 34793989 |
Cytopenia | 25.17 | 10.72 | 5 | 111649 | 12718 | 34832559 |
Blood bilirubin increased | 25.02 | 10.72 | 53 | 111601 | 38243 | 34807034 |
Medication error | 24.75 | 10.72 | 153 | 111501 | 25412 | 34819865 |
Purpura fulminans | 24.57 | 10.72 | 10 | 111644 | 92 | 34845185 |
Stoma site extravasation | 24.47 | 10.72 | 10 | 111644 | 93 | 34845184 |
International normalised ratio increased | 24.33 | 10.72 | 74 | 111580 | 47253 | 34798024 |
Brain oedema | 24.31 | 10.72 | 98 | 111556 | 13723 | 34831554 |
Gastrointestinal hypermotility | 24.24 | 10.72 | 11 | 111643 | 135 | 34845142 |
Rheumatoid arthritis | 24.08 | 10.72 | 54 | 111600 | 38184 | 34807093 |
Extrapyramidal disorder | 24.01 | 10.72 | 93 | 111561 | 12787 | 34832490 |
Hepatotoxicity | 23.98 | 10.72 | 20 | 111634 | 21465 | 34823812 |
Gambling disorder | 23.90 | 10.72 | 28 | 111626 | 1632 | 34843645 |
Talipes | 23.73 | 10.72 | 30 | 111624 | 1893 | 34843384 |
Palmar-plantar erythrodysaesthesia syndrome | 23.68 | 10.72 | 12 | 111642 | 16783 | 34828494 |
Feeling guilty | 23.54 | 10.72 | 14 | 111640 | 309 | 34844968 |
Asthenia | 23.51 | 10.72 | 600 | 111054 | 244651 | 34600626 |
Arthritis | 23.44 | 10.72 | 40 | 111614 | 31306 | 34813971 |
Off label use | 23.36 | 10.72 | 1099 | 110555 | 418425 | 34426852 |
Neoplasm progression | 23.27 | 10.72 | 24 | 111630 | 23276 | 34822001 |
Restless legs syndrome | 23.25 | 10.72 | 69 | 111585 | 8285 | 34836992 |
Muscle contracture | 23.14 | 10.72 | 24 | 111630 | 1220 | 34844057 |
Atonic seizures | 23.04 | 10.72 | 13 | 111641 | 259 | 34845018 |
Haematemesis | 22.97 | 10.72 | 33 | 111621 | 27678 | 34817599 |
Tumour lysis syndrome | 22.87 | 10.72 | 13 | 111641 | 17046 | 34828231 |
Tachyphrenia | 22.74 | 10.72 | 24 | 111630 | 1245 | 34844032 |
Treatment failure | 22.62 | 10.72 | 75 | 111579 | 46622 | 34798655 |
Stereotypy | 22.57 | 10.72 | 19 | 111635 | 739 | 34844538 |
Pulmonary embolism | 22.48 | 10.72 | 181 | 111473 | 89565 | 34755712 |
Blunted affect | 22.14 | 10.72 | 14 | 111640 | 346 | 34844931 |
Liver disorder | 22.11 | 10.72 | 45 | 111609 | 32952 | 34812325 |
Hepatic cirrhosis | 22.08 | 10.72 | 14 | 111640 | 17300 | 34827977 |
Pulmonary fibrosis | 21.95 | 10.72 | 16 | 111638 | 18380 | 34826897 |
Somnambulism | 21.93 | 10.72 | 37 | 111617 | 3035 | 34842242 |
Testicular infarction | 21.79 | 10.72 | 8 | 111646 | 54 | 34845223 |
Angina pectoris | 21.68 | 10.72 | 42 | 111612 | 31321 | 34813956 |
Gaze palsy | 21.59 | 10.72 | 27 | 111627 | 1685 | 34843592 |
Psychotic behaviour | 21.58 | 10.72 | 18 | 111636 | 691 | 34844586 |
Amnesia | 21.49 | 10.72 | 152 | 111502 | 26411 | 34818866 |
Cogwheel rigidity | 21.48 | 10.72 | 24 | 111630 | 1328 | 34843949 |
Chills | 21.45 | 10.72 | 161 | 111493 | 80882 | 34764395 |
Shock haemorrhagic | 21.36 | 10.72 | 5 | 111649 | 11349 | 34833928 |
Intensive care unit acquired weakness | 21.27 | 10.72 | 21 | 111633 | 1006 | 34844271 |
Physical assault | 21.13 | 10.72 | 22 | 111632 | 1123 | 34844154 |
Hypotonia | 21.04 | 10.72 | 64 | 111590 | 7789 | 34837488 |
Congenital melanocytic naevus | 21.03 | 10.72 | 6 | 111648 | 15 | 34845262 |
Cerebellar atrophy | 21.00 | 10.72 | 16 | 111638 | 538 | 34844739 |
Nephropathy toxic | 20.98 | 10.72 | 7 | 111647 | 12581 | 34832696 |
Ehlers-Danlos syndrome | 20.82 | 10.72 | 7 | 111647 | 35 | 34845242 |
Sinus tachycardia | 20.82 | 10.72 | 110 | 111544 | 17250 | 34828027 |
Psychiatric symptom | 20.81 | 10.72 | 39 | 111615 | 3474 | 34841803 |
Sedation complication | 20.79 | 10.72 | 27 | 111627 | 1750 | 34843527 |
Exposure via ingestion | 20.77 | 10.72 | 30 | 111624 | 2151 | 34843126 |
Personality disorder | 20.77 | 10.72 | 22 | 111632 | 1146 | 34844131 |
Parasomnia | 20.67 | 10.72 | 14 | 111640 | 390 | 34844887 |
Hypertension | 20.63 | 10.72 | 309 | 111345 | 136134 | 34709143 |
Upper gastrointestinal haemorrhage | 20.55 | 10.72 | 31 | 111623 | 25487 | 34819790 |
Multiple sclerosis | 20.54 | 10.72 | 57 | 111597 | 6588 | 34838689 |
Nystagmus | 20.43 | 10.72 | 46 | 111608 | 4669 | 34840608 |
Obsessive-compulsive personality disorder | 20.37 | 10.72 | 10 | 111644 | 148 | 34845129 |
Laboratory test abnormal | 20.37 | 10.72 | 21 | 111633 | 20370 | 34824907 |
Wrong patient received product | 20.33 | 10.72 | 33 | 111621 | 2621 | 34842656 |
Haemophagocytic lymphohistiocytosis | 20.28 | 10.72 | 8 | 111646 | 12965 | 34832312 |
Tooth injury | 20.20 | 10.72 | 22 | 111632 | 1183 | 34844094 |
Stoma site inflammation | 20.17 | 10.72 | 15 | 111639 | 486 | 34844791 |
Change in seizure presentation | 20.02 | 10.72 | 10 | 111644 | 154 | 34845123 |
Rhabdomyolysis | 19.86 | 10.72 | 317 | 111337 | 67846 | 34777431 |
Adrenal insufficiency | 19.86 | 10.72 | 10 | 111644 | 14037 | 34831240 |
Phaeochromocytoma malignant | 19.81 | 10.72 | 8 | 111646 | 72 | 34845205 |
Erectile dysfunction | 19.66 | 10.72 | 123 | 111531 | 20514 | 34824763 |
Drug tolerance | 19.63 | 10.72 | 34 | 111620 | 2848 | 34842429 |
Rash pruritic | 19.58 | 10.72 | 35 | 111619 | 26906 | 34818371 |
Parkinsonian gait | 19.52 | 10.72 | 15 | 111639 | 511 | 34844766 |
Stoma site infection | 19.51 | 10.72 | 18 | 111636 | 792 | 34844485 |
Blood prolactin increased | 19.44 | 10.72 | 26 | 111628 | 1734 | 34843543 |
Chronic kidney disease | 19.40 | 10.72 | 67 | 111587 | 41143 | 34804134 |
Thrombotic microangiopathy | 19.38 | 10.72 | 5 | 111649 | 10625 | 34834652 |
Weight increased | 19.19 | 10.72 | 410 | 111244 | 92623 | 34752654 |
Suspected suicide | 19.11 | 10.72 | 45 | 111609 | 4703 | 34840574 |
Hypomania | 18.99 | 10.72 | 30 | 111624 | 2329 | 34842948 |
Injection site exfoliation | 18.92 | 10.72 | 6 | 111648 | 24 | 34845253 |
Myalgia | 18.68 | 10.72 | 175 | 111479 | 83935 | 34761342 |
Clonic convulsion | 18.67 | 10.72 | 16 | 111638 | 638 | 34844639 |
Inflammation | 18.61 | 10.72 | 39 | 111615 | 28256 | 34817021 |
Antidepressant drug level increased | 18.59 | 10.72 | 9 | 111645 | 129 | 34845148 |
Language disorder | 18.59 | 10.72 | 29 | 111625 | 2227 | 34843050 |
Autonomic nervous system imbalance | 18.57 | 10.72 | 31 | 111623 | 2520 | 34842757 |
Cluster headache | 18.55 | 10.72 | 15 | 111639 | 551 | 34844726 |
Bradycardia | 18.45 | 10.72 | 341 | 111313 | 75077 | 34770200 |
Persecutory delusion | 18.32 | 10.72 | 31 | 111623 | 2549 | 34842728 |
Squamous cell carcinoma of skin | 18.22 | 10.72 | 6 | 111648 | 10875 | 34834402 |
Embedded device | 18.21 | 10.72 | 12 | 111642 | 319 | 34844958 |
Substance use disorder | 18.16 | 10.72 | 17 | 111637 | 762 | 34844515 |
Impulsive behaviour | 18.10 | 10.72 | 28 | 111626 | 2134 | 34843143 |
Postictal paralysis | 18.10 | 10.72 | 11 | 111643 | 253 | 34845024 |
Lethargy | 18.08 | 10.72 | 206 | 111448 | 40916 | 34804361 |
Major depression | 18.05 | 10.72 | 43 | 111611 | 4529 | 34840748 |
Hypersomnia | 18.00 | 10.72 | 83 | 111571 | 12324 | 34832953 |
Physical abuse | 17.97 | 10.72 | 5 | 111649 | 11 | 34845266 |
Postoperative respiratory failure | 17.93 | 10.72 | 9 | 111645 | 140 | 34845137 |
Swelling | 17.91 | 10.72 | 72 | 111582 | 42294 | 34802983 |
Road traffic accident | 17.89 | 10.72 | 106 | 111548 | 17344 | 34827933 |
Hyperchloraemia | 17.84 | 10.72 | 14 | 111640 | 492 | 34844785 |
HIV peripheral neuropathy | 17.84 | 10.72 | 6 | 111648 | 30 | 34845247 |
Nightmare | 17.81 | 10.72 | 92 | 111562 | 14299 | 34830978 |
Hyperthermia | 17.81 | 10.72 | 74 | 111580 | 10503 | 34834774 |
Arthropathy | 17.77 | 10.72 | 37 | 111617 | 26870 | 34818407 |
Infantile spasms | 17.69 | 10.72 | 10 | 111644 | 200 | 34845077 |
Abdominal pain | 17.67 | 10.72 | 393 | 111261 | 163225 | 34682052 |
Electrocardiogram QT shortened | 17.65 | 10.72 | 9 | 111645 | 145 | 34845132 |
Dysmetria | 17.52 | 10.72 | 15 | 111639 | 597 | 34844680 |
Injection site dryness | 17.37 | 10.72 | 6 | 111648 | 33 | 34845244 |
Oedema | 17.34 | 10.72 | 81 | 111573 | 45660 | 34799617 |
Rapid eye movement sleep behaviour disorder | 17.33 | 10.72 | 9 | 111645 | 151 | 34845126 |
Osteonecrosis of jaw | 17.23 | 10.72 | 19 | 111635 | 17870 | 34827407 |
Hypokalaemia | 17.19 | 10.72 | 112 | 111542 | 58102 | 34787175 |
Areflexia | 17.15 | 10.72 | 33 | 111621 | 2998 | 34842279 |
Opsoclonus myoclonus | 17.05 | 10.72 | 7 | 111647 | 66 | 34845211 |
Cholestasis | 17.01 | 10.72 | 38 | 111616 | 26910 | 34818367 |
Stupor | 17.01 | 10.72 | 32 | 111622 | 2859 | 34842418 |
Hyperarousal | 16.94 | 10.72 | 6 | 111648 | 36 | 34845241 |
Developmental regression | 16.94 | 10.72 | 6 | 111648 | 36 | 34845241 |
Dopamine dysregulation syndrome | 16.91 | 10.72 | 13 | 111641 | 443 | 34844834 |
Heat stroke | 16.85 | 10.72 | 18 | 111636 | 947 | 34844330 |
Treatment noncompliance | 16.81 | 10.72 | 150 | 111504 | 27950 | 34817327 |
Personality change | 16.80 | 10.72 | 45 | 111609 | 5094 | 34840183 |
Petit mal epilepsy | 16.80 | 10.72 | 33 | 111621 | 3045 | 34842232 |
Atrial flutter | 16.77 | 10.72 | 15 | 111639 | 15559 | 34829718 |
Bruxism | 16.72 | 10.72 | 24 | 111630 | 1711 | 34843566 |
Death | 16.70 | 10.72 | 1072 | 110582 | 396977 | 34448300 |
Blood uric acid increased | 16.66 | 10.72 | 5 | 111649 | 9619 | 34835658 |
Post-traumatic stress disorder | 16.65 | 10.72 | 25 | 111629 | 1856 | 34843421 |
Poverty of speech | 16.61 | 10.72 | 10 | 111644 | 226 | 34845051 |
Pneumothorax | 16.56 | 10.72 | 22 | 111632 | 19070 | 34826207 |
Lymphadenopathy | 16.49 | 10.72 | 42 | 111612 | 28421 | 34816856 |
Renal hypertension | 16.47 | 10.72 | 9 | 111645 | 168 | 34845109 |
Myositis | 16.46 | 10.72 | 9 | 111645 | 12061 | 34833216 |
Borderline personality disorder | 16.43 | 10.72 | 12 | 111642 | 378 | 34844899 |
Haemorrhage intracranial | 16.41 | 10.72 | 16 | 111638 | 15930 | 34829347 |
Syncope | 16.38 | 10.72 | 200 | 111454 | 91251 | 34754026 |
Hyperkinesia | 16.38 | 10.72 | 24 | 111630 | 1744 | 34843533 |
Suicidal behaviour | 16.36 | 10.72 | 22 | 111632 | 1475 | 34843802 |
Pulmonary hypertension | 16.29 | 10.72 | 26 | 111628 | 20898 | 34824379 |
Apathy | 16.29 | 10.72 | 54 | 111600 | 6878 | 34838399 |
Homicidal ideation | 16.17 | 10.72 | 30 | 111624 | 2652 | 34842625 |
Venoocclusive liver disease | 16.03 | 10.72 | 3 | 111651 | 7963 | 34837314 |
Dry skin | 16.02 | 10.72 | 49 | 111605 | 31238 | 34814039 |
Encephalopathy | 16.01 | 10.72 | 178 | 111476 | 35141 | 34810136 |
Bladder cancer | 15.99 | 10.72 | 17 | 111637 | 16261 | 34829016 |
Spinal shock | 15.92 | 10.72 | 6 | 111648 | 44 | 34845233 |
Depersonalisation/derealisation disorder | 15.88 | 10.72 | 14 | 111640 | 580 | 34844697 |
Weight abnormal | 15.84 | 10.72 | 15 | 111639 | 682 | 34844595 |
Pseudomonas infection | 15.80 | 10.72 | 10 | 111644 | 12372 | 34832905 |
Cardiac failure chronic | 15.79 | 10.72 | 3 | 111651 | 7876 | 34837401 |
Graft versus host disease | 15.75 | 10.72 | 7 | 111647 | 10562 | 34834715 |
Stoma site hypergranulation | 15.75 | 10.72 | 9 | 111645 | 184 | 34845093 |
Inappropriate affect | 15.73 | 10.72 | 15 | 111639 | 688 | 34844589 |
Tuberculosis | 15.70 | 10.72 | 4 | 111650 | 8573 | 34836704 |
Clonus | 15.64 | 10.72 | 30 | 111624 | 2720 | 34842557 |
Sexual dysfunction | 15.62 | 10.72 | 50 | 111604 | 6253 | 34839024 |
Hyperglycaemia | 15.51 | 10.72 | 69 | 111585 | 39411 | 34805866 |
Staphylococcal sepsis | 15.51 | 10.72 | 6 | 111648 | 9838 | 34835439 |
Postmortem blood drug level | 15.41 | 10.72 | 9 | 111645 | 192 | 34845085 |
Neurotoxicity | 15.37 | 10.72 | 21 | 111633 | 17989 | 34827288 |
Labelled drug-drug interaction medication error | 15.36 | 10.72 | 15 | 111639 | 14924 | 34830353 |
Staphylococcal bacteraemia | 15.36 | 10.72 | 4 | 111650 | 8448 | 34836829 |
Fluid retention | 15.33 | 10.72 | 40 | 111614 | 26847 | 34818430 |
Libido decreased | 15.23 | 10.72 | 41 | 111613 | 4655 | 34840622 |
Blood bicarbonate decreased | 15.22 | 10.72 | 28 | 111626 | 2459 | 34842818 |
Intelligence test abnormal | 15.21 | 10.72 | 5 | 111649 | 23 | 34845254 |
Aplastic anaemia | 15.18 | 10.72 | 6 | 111648 | 9710 | 34835567 |
Hostility | 15.13 | 10.72 | 16 | 111638 | 832 | 34844445 |
Feeling jittery | 15.10 | 10.72 | 37 | 111617 | 3966 | 34841311 |
Panic reaction | 15.10 | 10.72 | 21 | 111633 | 1454 | 34843823 |
Libido increased | 15.08 | 10.72 | 16 | 111638 | 835 | 34844442 |
Lymphopenia | 15.02 | 10.72 | 18 | 111636 | 16317 | 34828960 |
Self esteem decreased | 15.00 | 10.72 | 13 | 111641 | 526 | 34844751 |
Galactorrhoea | 14.90 | 10.72 | 12 | 111642 | 438 | 34844839 |
Antipsychotic drug level increased | 14.88 | 10.72 | 36 | 111618 | 3829 | 34841448 |
Asterixis | 14.84 | 10.72 | 19 | 111635 | 1214 | 34844063 |
Herpes zoster | 14.83 | 10.72 | 58 | 111596 | 34341 | 34810936 |
Obsessive thoughts | 14.83 | 10.72 | 15 | 111639 | 740 | 34844537 |
Hypocalcaemia | 14.73 | 10.72 | 35 | 111619 | 24254 | 34821023 |
Defect conduction intraventricular | 14.67 | 10.72 | 11 | 111643 | 361 | 34844916 |
Sleep-related eating disorder | 14.63 | 10.72 | 10 | 111644 | 283 | 34844994 |
Synovitis | 14.61 | 10.72 | 14 | 111640 | 14052 | 34831225 |
Oropharyngeal pain | 14.56 | 10.72 | 61 | 111593 | 35424 | 34809853 |
Conduction disorder | 14.51 | 10.72 | 25 | 111629 | 2085 | 34843192 |
Ejaculation disorder | 14.49 | 10.72 | 17 | 111637 | 992 | 34844285 |
Bacterial infection | 14.46 | 10.72 | 20 | 111634 | 17043 | 34828234 |
Substance dependence | 14.38 | 10.72 | 11 | 111643 | 372 | 34844905 |
Neurosis | 14.38 | 10.72 | 8 | 111646 | 155 | 34845122 |
Eye movement disorder | 14.37 | 10.72 | 37 | 111617 | 4090 | 34841187 |
Anhidrosis | 14.36 | 10.72 | 7 | 111647 | 102 | 34845175 |
Patient uncooperative | 14.33 | 10.72 | 12 | 111642 | 463 | 34844814 |
Anal spasm | 14.25 | 10.72 | 3 | 111651 | 0 | 34845277 |
Eustachian tube disorder | 14.25 | 10.72 | 3 | 111651 | 0 | 34845277 |
Clostridium difficile infection | 14.23 | 10.72 | 24 | 111630 | 18874 | 34826403 |
Mental status changes | 14.23 | 10.72 | 185 | 111469 | 37898 | 34807379 |
Cholangitis | 14.19 | 10.72 | 5 | 111649 | 8684 | 34836593 |
Hyperphagia | 14.18 | 10.72 | 20 | 111634 | 1403 | 34843874 |
Terminal insomnia | 14.03 | 10.72 | 13 | 111641 | 575 | 34844702 |
Jealous delusion | 14.03 | 10.72 | 10 | 111644 | 303 | 34844974 |
Gallbladder polyp | 14.01 | 10.72 | 11 | 111643 | 387 | 34844890 |
Gout | 14.00 | 10.72 | 25 | 111629 | 19228 | 34826049 |
Deep vein thrombosis | 13.96 | 10.72 | 137 | 111517 | 65111 | 34780166 |
Muscle spasticity | 13.95 | 10.72 | 46 | 111608 | 5842 | 34839435 |
Akinesia | 13.89 | 10.72 | 25 | 111629 | 2159 | 34843118 |
Incorrect route of product administration | 13.84 | 10.72 | 88 | 111566 | 14757 | 34830520 |
CADASIL | 13.83 | 10.72 | 7 | 111647 | 111 | 34845166 |
Facial bones fracture | 13.73 | 10.72 | 27 | 111627 | 2493 | 34842784 |
Abdominal pain upper | 13.71 | 10.72 | 154 | 111500 | 71336 | 34773941 |
Hallucinations, mixed | 13.68 | 10.72 | 28 | 111626 | 2661 | 34842616 |
Hyperosmolar state | 13.65 | 10.72 | 11 | 111643 | 402 | 34844875 |
Diverticulitis | 13.64 | 10.72 | 27 | 111627 | 19977 | 34825300 |
Staphylococcal infection | 13.64 | 10.72 | 56 | 111598 | 32704 | 34812573 |
Tachycardia | 13.64 | 10.72 | 361 | 111293 | 84411 | 34760866 |
Intellectual disability | 13.62 | 10.72 | 19 | 111635 | 1319 | 34843958 |
Purpura | 13.62 | 10.72 | 8 | 111646 | 10303 | 34834974 |
Locomotive syndrome | 13.49 | 10.72 | 4 | 111650 | 12 | 34845265 |
Monorchidism | 13.49 | 10.72 | 4 | 111650 | 12 | 34845265 |
Wrong schedule | 13.48 | 10.72 | 8 | 111646 | 176 | 34845101 |
Fatigue | 13.42 | 10.72 | 1011 | 110643 | 369642 | 34475635 |
Ammonia abnormal | 13.41 | 10.72 | 6 | 111648 | 71 | 34845206 |
Respiratory acidosis | 13.38 | 10.72 | 41 | 111613 | 5009 | 34840268 |
Pneumonia bacterial | 13.31 | 10.72 | 11 | 111643 | 11861 | 34833416 |
Urinary tract discomfort | 13.29 | 10.72 | 7 | 111647 | 121 | 34845156 |
Niemann-Pick disease | 13.25 | 10.72 | 4 | 111650 | 13 | 34845264 |
Drug level increased | 13.24 | 10.72 | 118 | 111536 | 21978 | 34823299 |
Dissociation | 13.23 | 10.72 | 21 | 111633 | 1637 | 34843640 |
Logorrhoea | 13.23 | 10.72 | 26 | 111628 | 2400 | 34842877 |
Rectal haemorrhage | 13.15 | 10.72 | 75 | 111579 | 40174 | 34805103 |
Epstein-Barr virus infection | 13.14 | 10.72 | 4 | 111650 | 7624 | 34837653 |
Glossopharyngeal nerve disorder | 13.11 | 10.72 | 5 | 111649 | 38 | 34845239 |
Social avoidant behaviour | 13.07 | 10.72 | 30 | 111624 | 3084 | 34842193 |
Brain hypoxia | 12.98 | 10.72 | 10 | 111644 | 342 | 34844935 |
Accommodation disorder | 12.94 | 10.72 | 9 | 111645 | 262 | 34845015 |
Haematuria traumatic | 12.90 | 10.72 | 8 | 111646 | 191 | 34845086 |
Blepharospasm | 12.86 | 10.72 | 17 | 111637 | 1121 | 34844156 |
Congenital cerebral cyst | 12.81 | 10.72 | 4 | 111650 | 15 | 34845262 |
Mutism | 12.73 | 10.72 | 15 | 111639 | 880 | 34844397 |
Dependence | 12.72 | 10.72 | 17 | 111637 | 1133 | 34844144 |
Cardiogenic shock | 12.72 | 10.72 | 43 | 111611 | 26575 | 34818702 |
Mumps | 12.71 | 10.72 | 6 | 111648 | 81 | 34845196 |
Cellulitis | 12.70 | 10.72 | 108 | 111546 | 52843 | 34792434 |
Skin ulcer | 12.70 | 10.72 | 33 | 111621 | 22183 | 34823094 |
Swelling face | 12.70 | 10.72 | 35 | 111619 | 23070 | 34822207 |
Senile dementia | 12.68 | 10.72 | 5 | 111649 | 42 | 34845235 |
Hypokinesia | 12.58 | 10.72 | 59 | 111595 | 8821 | 34836456 |
Hyponatraemia | 12.58 | 10.72 | 187 | 111467 | 82504 | 34762773 |
Bipolar I disorder | 12.56 | 10.72 | 14 | 111640 | 773 | 34844504 |
Dementia | 12.51 | 10.72 | 81 | 111573 | 13667 | 34831610 |
Lip swelling | 12.50 | 10.72 | 20 | 111634 | 16060 | 34829217 |
Hyperreflexia | 12.49 | 10.72 | 30 | 111624 | 3176 | 34842101 |
Blood osmolarity decreased | 12.43 | 10.72 | 12 | 111642 | 559 | 34844718 |
Acute coronary syndrome | 12.38 | 10.72 | 15 | 111639 | 13530 | 34831747 |
Malaise | 12.33 | 10.72 | 477 | 111177 | 185348 | 34659929 |
Hypercalcaemia | 12.25 | 10.72 | 19 | 111635 | 15449 | 34829828 |
Nervous system disorder | 12.22 | 10.72 | 84 | 111570 | 14459 | 34830818 |
Substance use | 12.21 | 10.72 | 13 | 111641 | 681 | 34844596 |
Hypothermia neonatal | 12.21 | 10.72 | 6 | 111648 | 89 | 34845188 |
Oesophageal food impaction | 12.21 | 10.72 | 6 | 111648 | 89 | 34845188 |
Product complaint | 12.20 | 10.72 | 44 | 111610 | 5846 | 34839431 |
White blood cell analysis abnormal | 12.18 | 10.72 | 3 | 111651 | 3 | 34845274 |
Medical device site scab | 12.18 | 10.72 | 3 | 111651 | 3 | 34845274 |
Pseudodementia | 12.18 | 10.72 | 3 | 111651 | 3 | 34845274 |
Muscle twitching | 12.17 | 10.72 | 65 | 111589 | 10233 | 34835044 |
Communication disorder | 12.16 | 10.72 | 26 | 111628 | 2548 | 34842729 |
Fibroma | 12.12 | 10.72 | 10 | 111644 | 378 | 34844899 |
Haemoptysis | 12.11 | 10.72 | 64 | 111590 | 34942 | 34810335 |
Lennox-Gastaut syndrome | 12.10 | 10.72 | 5 | 111649 | 48 | 34845229 |
Rabbit syndrome | 12.06 | 10.72 | 4 | 111650 | 19 | 34845258 |
Bladder dilatation | 12.04 | 10.72 | 19 | 111635 | 1473 | 34843804 |
Post transplant lymphoproliferative disorder | 12.04 | 10.72 | 3 | 111651 | 6525 | 34838752 |
Optic nerve operation | 12.02 | 10.72 | 11 | 111643 | 479 | 34844798 |
Frustration tolerance decreased | 12.01 | 10.72 | 26 | 111628 | 2570 | 34842707 |
Candida infection | 12.00 | 10.72 | 24 | 111630 | 17691 | 34827586 |
Viral upper respiratory tract infection | 12.00 | 10.72 | 27 | 111627 | 2739 | 34842538 |
Illusion | 11.99 | 10.72 | 14 | 111640 | 813 | 34844464 |
Developmental hip dysplasia | 11.99 | 10.72 | 9 | 111645 | 296 | 34844981 |
Allodynia | 11.94 | 10.72 | 14 | 111640 | 817 | 34844460 |
Urinary incontinence | 11.93 | 10.72 | 102 | 111552 | 18772 | 34826505 |
Hemiparesis | 11.92 | 10.72 | 20 | 111634 | 15758 | 34829519 |
Dementia with Lewy bodies | 11.89 | 10.72 | 13 | 111641 | 702 | 34844575 |
Anticonvulsant drug level decreased | 11.86 | 10.72 | 16 | 111638 | 1076 | 34844201 |
Diet refusal | 11.86 | 10.72 | 9 | 111645 | 301 | 34844976 |
Spasmodic dysphonia | 11.84 | 10.72 | 8 | 111646 | 222 | 34845055 |
Renal injury | 11.79 | 10.72 | 11 | 111643 | 11184 | 34834093 |
Nasal septum deviation | 11.78 | 10.72 | 16 | 111638 | 1083 | 34844194 |
Jaundice | 11.77 | 10.72 | 57 | 111597 | 31825 | 34813452 |
Confusional arousal | 11.74 | 10.72 | 4 | 111650 | 21 | 34845256 |
Antisocial behaviour | 11.70 | 10.72 | 10 | 111644 | 397 | 34844880 |
Somatic delusion | 11.70 | 10.72 | 6 | 111648 | 98 | 34845179 |
Hypoxia | 11.65 | 10.72 | 116 | 111538 | 54979 | 34790298 |
Hypoalbuminaemia | 11.64 | 10.72 | 13 | 111641 | 12161 | 34833116 |
Paradoxical drug reaction | 11.62 | 10.72 | 30 | 111624 | 3321 | 34841956 |
Mood altered | 11.62 | 10.72 | 58 | 111596 | 8894 | 34836383 |
Pain | 11.57 | 10.72 | 535 | 111119 | 204140 | 34641137 |
Open reduction of fracture | 11.48 | 10.72 | 6 | 111648 | 102 | 34845175 |
Brain malformation | 11.44 | 10.72 | 7 | 111647 | 163 | 34845114 |
Immunosuppression | 11.43 | 10.72 | 3 | 111651 | 6301 | 34838976 |
Lung neoplasm malignant | 11.42 | 10.72 | 24 | 111630 | 17371 | 34827906 |
C-reactive protein increased | 11.40 | 10.72 | 114 | 111540 | 53984 | 34791293 |
Blood loss anaemia | 11.34 | 10.72 | 6 | 111648 | 8188 | 34837089 |
Quadriparesis | 11.33 | 10.72 | 19 | 111635 | 1550 | 34843727 |
Anaphylactic shock | 11.32 | 10.72 | 21 | 111633 | 15920 | 34829357 |
Perineal infection | 11.30 | 10.72 | 12 | 111642 | 627 | 34844650 |
Dissociative identity disorder | 11.29 | 10.72 | 4 | 111650 | 24 | 34845253 |
Disseminated intravascular coagulation | 11.29 | 10.72 | 34 | 111620 | 21782 | 34823495 |
Bulbar palsy | 11.26 | 10.72 | 8 | 111646 | 241 | 34845036 |
Hyperhidrosis | 11.23 | 10.72 | 319 | 111335 | 75373 | 34769904 |
Partial seizures with secondary generalisation | 11.21 | 10.72 | 9 | 111645 | 327 | 34844950 |
Alopecia | 11.19 | 10.72 | 40 | 111614 | 24315 | 34820962 |
Pyelonephritis | 11.18 | 10.72 | 3 | 111651 | 6212 | 34839065 |
Pulmonary alveolar haemorrhage | 11.15 | 10.72 | 5 | 111649 | 7507 | 34837770 |
Pneumonitis | 11.14 | 10.72 | 63 | 111591 | 33815 | 34811462 |
Multiple sclerosis relapse | 11.12 | 10.72 | 76 | 111578 | 13057 | 34832220 |
Infected dermal cyst | 11.11 | 10.72 | 14 | 111640 | 880 | 34844397 |
Persistent depressive disorder | 11.10 | 10.72 | 9 | 111645 | 332 | 34844945 |
Scrotal infection | 11.08 | 10.72 | 12 | 111642 | 641 | 34844636 |
Drug eruption | 11.04 | 10.72 | 30 | 111624 | 19868 | 34825409 |
Full blood count decreased | 11.02 | 10.72 | 26 | 111628 | 18062 | 34827215 |
Blood pressure systolic increased | 11.02 | 10.72 | 37 | 111617 | 22915 | 34822362 |
Appendicitis | 10.97 | 10.72 | 19 | 111635 | 14788 | 34830489 |
Irregular sleep phase | 10.97 | 10.72 | 5 | 111649 | 62 | 34845215 |
Sleep paralysis | 10.93 | 10.72 | 7 | 111647 | 177 | 34845100 |
Pre-existing condition improved | 10.91 | 10.72 | 25 | 111629 | 2567 | 34842710 |
Gastric haemorrhage | 10.91 | 10.72 | 10 | 111644 | 10251 | 34835026 |
Antisocial personality disorder | 10.90 | 10.72 | 5 | 111649 | 63 | 34845214 |
Medical device site dryness | 10.89 | 10.72 | 4 | 111650 | 27 | 34845250 |
Schizoaffective disorder | 10.85 | 10.72 | 17 | 111637 | 1310 | 34843967 |
Prostatic specific antigen increased | 10.73 | 10.72 | 19 | 111635 | 14661 | 34830616 |
Hypervolaemia | 10.72 | 10.72 | 30 | 111624 | 19679 | 34825598 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Completed suicide | 3442.21 | 9.80 | 4114 | 255614 | 241653 | 79243007 |
Drug abuse | 1906.51 | 9.80 | 2494 | 257234 | 160197 | 79324463 |
Toxicity to various agents | 1629.25 | 9.80 | 3968 | 255760 | 417572 | 79067088 |
Respiratory arrest | 836.30 | 9.80 | 984 | 258744 | 56566 | 79428094 |
Depression | 827.51 | 9.80 | 2034 | 257694 | 214756 | 79269904 |
Suicide attempt | 822.69 | 9.80 | 1174 | 258554 | 81758 | 79402902 |
Intentional overdose | 797.75 | 9.80 | 1320 | 258408 | 104640 | 79380020 |
Somnolence | 717.69 | 9.80 | 2051 | 257677 | 236930 | 79247730 |
Sopor | 697.21 | 9.80 | 688 | 259040 | 32322 | 79452338 |
Cardio-respiratory arrest | 653.86 | 9.80 | 1226 | 258502 | 107284 | 79377376 |
Overdose | 644.86 | 9.80 | 1673 | 258055 | 182533 | 79302127 |
Suicidal ideation | 578.40 | 9.80 | 954 | 258774 | 75386 | 79409274 |
Psychotic disorder | 523.53 | 9.80 | 660 | 259068 | 40742 | 79443918 |
Poisoning | 452.52 | 9.80 | 482 | 259246 | 24790 | 79459870 |
Cardiac arrest | 450.76 | 9.80 | 1408 | 258320 | 170688 | 79313972 |
Drug dependence | 441.15 | 9.80 | 602 | 259126 | 40167 | 79444493 |
Seizure | 429.94 | 9.80 | 1473 | 258255 | 187361 | 79297299 |
Drug withdrawal syndrome | 422.42 | 9.80 | 543 | 259185 | 34175 | 79450485 |
Drug interaction | 421.28 | 9.80 | 2548 | 257180 | 412635 | 79072025 |
Neuroleptic malignant syndrome | 418.21 | 9.80 | 482 | 259246 | 27077 | 79457583 |
Synovitis | 404.18 | 9.80 | 21 | 259707 | 150713 | 79333947 |
Anxiety | 377.71 | 9.80 | 1707 | 258021 | 246805 | 79237855 |
Contraindicated product administered | 371.47 | 9.80 | 40 | 259688 | 157498 | 79327162 |
Coma | 367.22 | 9.80 | 929 | 258799 | 99720 | 79384940 |
Intentional self-injury | 366.42 | 9.80 | 489 | 259239 | 31930 | 79452730 |
Agitation | 357.16 | 9.80 | 914 | 258814 | 98801 | 79385859 |
Aggression | 337.41 | 9.80 | 600 | 259128 | 50358 | 79434302 |
Acute kidney injury | 307.89 | 9.80 | 782 | 258946 | 518622 | 78966038 |
Febrile neutropenia | 305.66 | 9.80 | 187 | 259541 | 230812 | 79253848 |
Abnormal behaviour | 295.95 | 9.80 | 470 | 259258 | 35951 | 79448709 |
Drug intolerance | 294.66 | 9.80 | 256 | 259472 | 263863 | 79220797 |
Intentional product misuse | 291.15 | 9.80 | 823 | 258905 | 94342 | 79390318 |
Miosis | 284.18 | 9.80 | 302 | 259426 | 15487 | 79469173 |
Infusion related reaction | 275.72 | 9.80 | 208 | 259520 | 230029 | 79254631 |
Depressed level of consciousness | 271.76 | 9.80 | 811 | 258917 | 95841 | 79388819 |
Anaemia | 262.82 | 9.80 | 671 | 259057 | 444344 | 79040316 |
Hand deformity | 262.09 | 9.80 | 20 | 259708 | 103899 | 79380761 |
Panic attack | 253.54 | 9.80 | 352 | 259376 | 23864 | 79460796 |
Schizophrenia | 249.44 | 9.80 | 279 | 259449 | 15161 | 79469499 |
Stubbornness | 247.58 | 9.80 | 79 | 259649 | 316 | 79484344 |
Serotonin syndrome | 246.78 | 9.80 | 489 | 259239 | 44538 | 79440122 |
Psychiatric decompensation | 243.22 | 9.80 | 155 | 259573 | 3808 | 79480852 |
Tremor | 241.71 | 9.80 | 1146 | 258582 | 168937 | 79315723 |
Joint swelling | 239.08 | 9.80 | 356 | 259372 | 288290 | 79196370 |
Pericarditis | 236.89 | 9.80 | 30 | 259698 | 104206 | 79380454 |
Systemic lupus erythematosus | 233.41 | 9.80 | 54 | 259674 | 121095 | 79363565 |
Rash | 232.12 | 9.80 | 1032 | 258696 | 577326 | 78907334 |
Dyskinesia | 231.96 | 9.80 | 475 | 259253 | 44298 | 79440362 |
Paranoia | 230.21 | 9.80 | 300 | 259428 | 19132 | 79465528 |
Arthropathy | 223.82 | 9.80 | 151 | 259577 | 176960 | 79307700 |
General physical health deterioration | 215.03 | 9.80 | 353 | 259375 | 274885 | 79209775 |
Substance abuse | 212.25 | 9.80 | 214 | 259514 | 10312 | 79474348 |
Speech disorder | 209.49 | 9.80 | 513 | 259215 | 53932 | 79430728 |
Rheumatoid arthritis | 196.09 | 9.80 | 234 | 259494 | 208236 | 79276424 |
Thinking abnormal | 195.98 | 9.80 | 228 | 259500 | 12933 | 79471727 |
Helicobacter infection | 195.77 | 9.80 | 7 | 259721 | 69697 | 79414963 |
Sedation | 195.46 | 9.80 | 485 | 259243 | 51410 | 79433250 |
Glossodynia | 195.25 | 9.80 | 48 | 259680 | 103289 | 79381371 |
Mydriasis | 193.05 | 9.80 | 262 | 259466 | 17381 | 79467279 |
Irritability | 192.82 | 9.80 | 419 | 259309 | 40725 | 79443935 |
Ataxia | 190.98 | 9.80 | 314 | 259414 | 24725 | 79459935 |
Insomnia | 181.90 | 9.80 | 1394 | 258334 | 243776 | 79240884 |
Hypersensitivity | 175.04 | 9.80 | 370 | 259358 | 261869 | 79222791 |
Treatment failure | 173.91 | 9.80 | 179 | 259549 | 170307 | 79314353 |
Stomatitis | 171.27 | 9.80 | 136 | 259592 | 146621 | 79338039 |
Altered state of consciousness | 168.68 | 9.80 | 413 | 259315 | 43409 | 79441251 |
Thrombocytopenia | 168.21 | 9.80 | 385 | 259343 | 264874 | 79219786 |
Rheumatoid factor positive | 168.08 | 9.80 | 6 | 259722 | 59833 | 79424827 |
Drug withdrawal convulsions | 167.31 | 9.80 | 99 | 259629 | 2121 | 79482539 |
Unresponsive to stimuli | 166.21 | 9.80 | 478 | 259250 | 55310 | 79429350 |
Alopecia | 163.28 | 9.80 | 316 | 259412 | 231039 | 79253621 |
Diarrhoea | 162.64 | 9.80 | 1962 | 257766 | 878527 | 78606133 |
Dystonia | 158.70 | 9.80 | 265 | 259463 | 21134 | 79463526 |
Sensitisation | 158.60 | 9.80 | 111 | 259617 | 3200 | 79481460 |
Infection | 157.18 | 9.80 | 346 | 259382 | 241366 | 79243294 |
Status epilepticus | 156.99 | 9.80 | 288 | 259440 | 24753 | 79459907 |
Pancytopenia | 155.89 | 9.80 | 186 | 259542 | 165559 | 79319101 |
Mental disorder | 154.99 | 9.80 | 326 | 259402 | 30976 | 79453684 |
Muscle rigidity | 153.89 | 9.80 | 251 | 259477 | 19631 | 79465029 |
Sepsis | 152.93 | 9.80 | 414 | 259314 | 269014 | 79215646 |
Disease progression | 152.92 | 9.80 | 227 | 259501 | 184135 | 79300525 |
Atrial fibrillation | 152.44 | 9.80 | 256 | 259472 | 197630 | 79287030 |
Polycystic ovaries | 152.08 | 9.80 | 114 | 259614 | 3665 | 79480995 |
Swelling | 152.06 | 9.80 | 297 | 259431 | 216414 | 79268246 |
Withdrawal syndrome | 149.98 | 9.80 | 294 | 259434 | 26560 | 79458100 |
Tardive dyskinesia | 148.90 | 9.80 | 178 | 259550 | 10393 | 79474267 |
Neutropenia | 148.78 | 9.80 | 462 | 259266 | 287248 | 79197412 |
Hallucination | 145.28 | 9.80 | 609 | 259119 | 85136 | 79399524 |
Interstitial lung disease | 143.56 | 9.80 | 95 | 259633 | 112505 | 79372155 |
Malignant neoplasm progression | 143.01 | 9.80 | 139 | 259589 | 135851 | 79348809 |
Bradyphrenia | 141.46 | 9.80 | 174 | 259554 | 10466 | 79474194 |
Psychomotor skills impaired | 139.06 | 9.80 | 124 | 259604 | 5113 | 79479547 |
Depression suicidal | 137.31 | 9.80 | 108 | 259620 | 3734 | 79480926 |
Tearfulness | 136.98 | 9.80 | 131 | 259597 | 5914 | 79478746 |
Impaired healing | 133.57 | 9.80 | 59 | 259669 | 87596 | 79397064 |
Mania | 131.25 | 9.80 | 223 | 259505 | 18037 | 79466623 |
Drug hypersensitivity | 131.02 | 9.80 | 515 | 259213 | 298401 | 79186259 |
Ejection fraction | 130.02 | 9.80 | 85 | 259643 | 2184 | 79482476 |
Pneumonia aspiration | 129.76 | 9.80 | 496 | 259232 | 66471 | 79418189 |
Abdominal discomfort | 129.34 | 9.80 | 403 | 259325 | 250324 | 79234336 |
Folliculitis | 128.12 | 9.80 | 15 | 259713 | 55365 | 79429295 |
Wound | 127.76 | 9.80 | 114 | 259614 | 116065 | 79368595 |
Crying | 124.73 | 9.80 | 249 | 259479 | 22794 | 79461866 |
Feeling of despair | 124.57 | 9.80 | 90 | 259638 | 2731 | 79481929 |
Granulocytopenia | 122.41 | 9.80 | 168 | 259560 | 11263 | 79473397 |
Restlessness | 122.08 | 9.80 | 381 | 259347 | 46111 | 79438549 |
Restless legs syndrome | 120.84 | 9.80 | 227 | 259501 | 19865 | 79464795 |
Bradykinesia | 119.19 | 9.80 | 139 | 259589 | 7904 | 79476756 |
On and off phenomenon | 117.78 | 9.80 | 92 | 259636 | 3148 | 79481512 |
Rhinitis allergic | 117.59 | 9.80 | 171 | 259557 | 12098 | 79472562 |
Disturbance in attention | 116.90 | 9.80 | 398 | 259330 | 50403 | 79434257 |
Drooling | 116.64 | 9.80 | 119 | 259609 | 5815 | 79478845 |
Arthralgia | 116.32 | 9.80 | 1246 | 258482 | 570557 | 78914103 |
Renal impairment | 116.15 | 9.80 | 210 | 259518 | 157573 | 79327087 |
Hallucination, auditory | 116.10 | 9.80 | 227 | 259501 | 20466 | 79464194 |
Dysarthria | 115.88 | 9.80 | 482 | 259246 | 67140 | 79417520 |
Platelet count decreased | 115.85 | 9.80 | 292 | 259436 | 194372 | 79290288 |
Mood altered | 115.35 | 9.80 | 208 | 259520 | 17639 | 79467021 |
Parkinsonism | 114.56 | 9.80 | 199 | 259529 | 16385 | 79468275 |
Depressive symptom | 114.07 | 9.80 | 122 | 259606 | 6301 | 79478359 |
Anger | 112.18 | 9.80 | 201 | 259527 | 16961 | 79467699 |
Generalised tonic-clonic seizure | 111.77 | 9.80 | 356 | 259372 | 43554 | 79441106 |
Off label use | 111.49 | 9.80 | 2185 | 257543 | 905030 | 78579630 |
Maternal exposure during pregnancy | 111.38 | 9.80 | 170 | 259558 | 136368 | 79348292 |
Pleural effusion | 110.85 | 9.80 | 189 | 259539 | 145073 | 79339587 |
Gastrointestinal haemorrhage | 108.37 | 9.80 | 197 | 259531 | 147522 | 79337138 |
Akathisia | 107.54 | 9.80 | 171 | 259557 | 13088 | 79471572 |
Salivary hypersecretion | 105.28 | 9.80 | 176 | 259552 | 14048 | 79470612 |
Respiratory depression | 103.78 | 9.80 | 258 | 259470 | 27372 | 79457288 |
Loss of consciousness | 100.96 | 9.80 | 911 | 258817 | 167032 | 79317628 |
Cogwheel rigidity | 100.14 | 9.80 | 82 | 259646 | 3006 | 79481654 |
Therapeutic product effect decreased | 99.68 | 9.80 | 243 | 259485 | 163620 | 79321040 |
Muscle injury | 98.94 | 9.80 | 19 | 259709 | 48542 | 79436118 |
Balance disorder | 98.73 | 9.80 | 605 | 259123 | 98252 | 79386408 |
Hyperkalaemia | 98.63 | 9.80 | 137 | 259591 | 114261 | 79370399 |
Dyspnoea | 98.42 | 9.80 | 2087 | 257641 | 854938 | 78629722 |
Myelosuppression | 98.16 | 9.80 | 9 | 259719 | 40287 | 79444373 |
Psychomotor hyperactivity | 95.95 | 9.80 | 186 | 259542 | 16663 | 79467997 |
Cardiac failure | 95.47 | 9.80 | 228 | 259500 | 154614 | 79330046 |
Dissociation | 94.66 | 9.80 | 89 | 259639 | 3932 | 79480728 |
Delusion | 92.29 | 9.80 | 205 | 259523 | 20218 | 79464442 |
Multiple sclerosis | 92.20 | 9.80 | 216 | 259512 | 22066 | 79462594 |
Pyrexia | 91.51 | 9.80 | 1608 | 258120 | 677101 | 78807559 |
Drug use disorder | 90.92 | 9.80 | 126 | 259602 | 8525 | 79476135 |
Myoglobin urine present | 89.60 | 9.80 | 49 | 259679 | 898 | 79483762 |
Gait disturbance | 88.72 | 9.80 | 1050 | 258678 | 206456 | 79278204 |
Mucosal inflammation | 86.95 | 9.80 | 71 | 259657 | 75509 | 79409151 |
Catatonia | 86.78 | 9.80 | 124 | 259604 | 8632 | 79476028 |
Epilepsy | 84.44 | 9.80 | 309 | 259419 | 40551 | 79444109 |
Gastric pH decreased | 84.26 | 9.80 | 46 | 259682 | 840 | 79483820 |
Memory impairment | 84.24 | 9.80 | 638 | 259090 | 111096 | 79373564 |
Peripheral swelling | 83.32 | 9.80 | 525 | 259203 | 269092 | 79215568 |
Drug abuser | 82.64 | 9.80 | 100 | 259628 | 5913 | 79478747 |
Middle insomnia | 82.64 | 9.80 | 170 | 259558 | 15899 | 79468761 |
Disorientation | 82.62 | 9.80 | 414 | 259314 | 62362 | 79422298 |
Hypersomnia | 81.94 | 9.80 | 211 | 259517 | 22875 | 79461785 |
Bone marrow failure | 81.72 | 9.80 | 32 | 259696 | 51075 | 79433585 |
Feeling abnormal | 81.56 | 9.80 | 835 | 258893 | 158364 | 79326296 |
Lactic acidosis | 81.06 | 9.80 | 66 | 259662 | 70293 | 79414367 |
Psychomotor retardation | 80.39 | 9.80 | 100 | 259628 | 6084 | 79478576 |
Discomfort | 79.81 | 9.80 | 182 | 259546 | 125435 | 79359225 |
Multiple-drug resistance | 79.00 | 9.80 | 119 | 259609 | 8689 | 79475971 |
Renal failure | 78.90 | 9.80 | 361 | 259367 | 200607 | 79284053 |
Hyperprolactinaemia | 78.11 | 9.80 | 86 | 259642 | 4590 | 79480070 |
Bipolar disorder | 77.65 | 9.80 | 110 | 259618 | 7597 | 79477063 |
Myocardial infarction | 77.61 | 9.80 | 322 | 259406 | 183807 | 79300853 |
Blood creatinine increased | 77.27 | 9.80 | 253 | 259475 | 154804 | 79329856 |
Hepatic enzyme increased | 77.18 | 9.80 | 319 | 259409 | 182291 | 79302369 |
Stoma site discharge | 76.59 | 9.80 | 61 | 259667 | 2148 | 79482512 |
Rheumatic fever | 76.34 | 9.80 | 4 | 259724 | 28521 | 79456139 |
Sleep apnoea syndrome | 76.34 | 9.80 | 277 | 259451 | 36201 | 79448459 |
Derealisation | 76.01 | 9.80 | 54 | 259674 | 1595 | 79483065 |
Lower respiratory tract infection | 75.95 | 9.80 | 195 | 259533 | 129025 | 79355635 |
Melaena | 75.42 | 9.80 | 53 | 259675 | 60837 | 79423823 |
Victim of crime | 74.81 | 9.80 | 35 | 259693 | 453 | 79484207 |
Urinary tract discomfort | 74.73 | 9.80 | 40 | 259688 | 701 | 79483959 |
Cytomegalovirus infection | 74.56 | 9.80 | 23 | 259705 | 42621 | 79442039 |
Nervousness | 74.43 | 9.80 | 259 | 259469 | 33156 | 79451504 |
Cardiac failure congestive | 73.30 | 9.80 | 229 | 259499 | 142173 | 79342487 |
Nightmare | 72.62 | 9.80 | 217 | 259511 | 25644 | 79459016 |
Hyperhidrosis | 72.62 | 9.80 | 784 | 258944 | 150708 | 79333952 |
Toxic encephalopathy | 72.24 | 9.80 | 132 | 259596 | 11308 | 79473352 |
Irritable bowel syndrome | 70.94 | 9.80 | 59 | 259669 | 62182 | 79422478 |
Blood creatine phosphokinase increased | 70.80 | 9.80 | 412 | 259316 | 65678 | 79418982 |
Angioedema | 70.74 | 9.80 | 86 | 259642 | 75949 | 79408711 |
Anticonvulsant drug level above therapeutic | 69.88 | 9.80 | 45 | 259683 | 1126 | 79483534 |
Alveolar osteitis | 69.81 | 9.80 | 40 | 259688 | 805 | 79483855 |
Ascites | 69.73 | 9.80 | 86 | 259642 | 75476 | 79409184 |
Septic shock | 69.37 | 9.80 | 189 | 259539 | 122612 | 79362048 |
Movement disorder | 69.36 | 9.80 | 221 | 259507 | 27038 | 79457622 |
Emotional disorder | 69.09 | 9.80 | 148 | 259580 | 14239 | 79470421 |
Haematochezia | 67.80 | 9.80 | 113 | 259615 | 87532 | 79397128 |
Exposure via ingestion | 67.80 | 9.80 | 84 | 259644 | 5090 | 79479570 |
Mood swings | 67.79 | 9.80 | 179 | 259549 | 19701 | 79464959 |
Hypokinesia | 67.44 | 9.80 | 174 | 259554 | 18886 | 79465774 |
Depersonalisation/derealisation disorder | 65.81 | 9.80 | 52 | 259676 | 1810 | 79482850 |
Mental impairment | 65.53 | 9.80 | 172 | 259556 | 18864 | 79465796 |
Fall | 65.50 | 9.80 | 2064 | 257664 | 485565 | 78999095 |
Sleep disorder due to general medical condition, insomnia type | 65.28 | 9.80 | 30 | 259698 | 43526 | 79441134 |
Multiple sclerosis relapse | 64.88 | 9.80 | 312 | 259416 | 46221 | 79438439 |
Electrocardiogram QRS complex prolonged | 64.65 | 9.80 | 122 | 259606 | 10711 | 79473949 |
COVID-19 | 64.43 | 9.80 | 279 | 259449 | 157395 | 79327265 |
Hypoaesthesia oral | 64.07 | 9.80 | 142 | 259586 | 13982 | 79470678 |
Electroencephalogram abnormal | 62.97 | 9.80 | 83 | 259645 | 5351 | 79479309 |
Inflammation | 62.71 | 9.80 | 132 | 259596 | 93621 | 79391039 |
Pulmonary fibrosis | 62.15 | 9.80 | 33 | 259695 | 44079 | 79440581 |
Pneumocystis jirovecii pneumonia | 61.58 | 9.80 | 15 | 259713 | 32493 | 79452167 |
C-reactive protein increased | 60.56 | 9.80 | 216 | 259512 | 128811 | 79355849 |
Electrocardiogram QT prolonged | 60.39 | 9.80 | 502 | 259226 | 89884 | 79394776 |
Loss of personal independence in daily activities | 60.36 | 9.80 | 554 | 259174 | 102026 | 79382634 |
Mental status changes | 60.17 | 9.80 | 399 | 259329 | 66560 | 79418100 |
Carpal tunnel syndrome | 58.80 | 9.80 | 168 | 259560 | 19360 | 79465300 |
Jaundice cholestatic | 58.76 | 9.80 | 120 | 259608 | 11164 | 79473496 |
Bradypnoea | 57.49 | 9.80 | 84 | 259644 | 5968 | 79478692 |
Urticaria | 56.99 | 9.80 | 361 | 259367 | 184840 | 79299820 |
Feeling of body temperature change | 56.61 | 9.80 | 78 | 259650 | 5248 | 79479412 |
Dopamine dysregulation syndrome | 55.23 | 9.80 | 29 | 259699 | 488 | 79484172 |
Musculoskeletal pain | 54.52 | 9.80 | 162 | 259566 | 102192 | 79382468 |
Animal scratch | 53.90 | 9.80 | 42 | 259686 | 1432 | 79483228 |
Bladder pain | 53.63 | 9.80 | 51 | 259677 | 2286 | 79482374 |
Stoma site erythema | 53.62 | 9.80 | 45 | 259683 | 1708 | 79482952 |
Neuropathy peripheral | 53.57 | 9.80 | 257 | 259471 | 141048 | 79343612 |
Drug screen positive | 53.08 | 9.80 | 81 | 259647 | 5982 | 79478678 |
Burning sensation | 53.06 | 9.80 | 350 | 259378 | 58282 | 79426378 |
Myoclonic epilepsy | 53.01 | 9.80 | 47 | 259681 | 1923 | 79482737 |
Red blood cell sedimentation rate abnormal | 52.94 | 9.80 | 4 | 259724 | 20959 | 79463701 |
Dysphoria | 52.85 | 9.80 | 71 | 259657 | 4663 | 79479997 |
Haemoglobin decreased | 52.61 | 9.80 | 466 | 259262 | 221653 | 79263007 |
Galactorrhoea | 52.35 | 9.80 | 62 | 259666 | 3584 | 79481076 |
Hypercalcaemia | 52.33 | 9.80 | 30 | 259698 | 38400 | 79446260 |
Cytokine release syndrome | 52.10 | 9.80 | 26 | 259702 | 35972 | 79448688 |
Neutrophil count decreased | 52.03 | 9.80 | 146 | 259582 | 93813 | 79390847 |
Incontinence | 51.87 | 9.80 | 131 | 259597 | 14033 | 79470627 |
Ill-defined disorder | 51.82 | 9.80 | 84 | 259644 | 65791 | 79418869 |
Colitis | 51.77 | 9.80 | 100 | 259628 | 73207 | 79411453 |
Tunnel vision | 51.37 | 9.80 | 42 | 259686 | 1536 | 79483124 |
Erythema | 51.34 | 9.80 | 472 | 259256 | 222818 | 79261842 |
Transplant rejection | 51.17 | 9.80 | 3 | 259725 | 19434 | 79465226 |
Palmar-plantar erythrodysaesthesia syndrome | 50.95 | 9.80 | 22 | 259706 | 33112 | 79451548 |
Abnormal dreams | 50.94 | 9.80 | 114 | 259614 | 11298 | 79473362 |
Proteinuria | 50.90 | 9.80 | 21 | 259707 | 32481 | 79452179 |
Hyperammonaemia | 50.86 | 9.80 | 112 | 259616 | 10981 | 79473679 |
Tension | 50.62 | 9.80 | 67 | 259661 | 4337 | 79480323 |
Lethargy | 50.36 | 9.80 | 444 | 259284 | 80848 | 79403812 |
Neutropenic sepsis | 50.28 | 9.80 | 13 | 259715 | 27051 | 79457609 |
Amnesia | 49.75 | 9.80 | 364 | 259364 | 62693 | 79421967 |
Pruritus | 49.59 | 9.80 | 946 | 258782 | 393702 | 79090958 |
Multiple organ dysfunction syndrome | 49.59 | 9.80 | 212 | 259516 | 120034 | 79364626 |
Hallucinations, mixed | 49.24 | 9.80 | 84 | 259644 | 6815 | 79477845 |
Nystagmus | 48.85 | 9.80 | 103 | 259625 | 9801 | 79474859 |
Myoclonus | 48.82 | 9.80 | 199 | 259529 | 27461 | 79457199 |
Nasopharyngitis | 48.78 | 9.80 | 560 | 259168 | 253321 | 79231339 |
Myocardial stunning | 48.66 | 9.80 | 20 | 259708 | 185 | 79484475 |
Acute myocardial infarction | 48.61 | 9.80 | 112 | 259616 | 76924 | 79407736 |
Hip arthroplasty | 48.56 | 9.80 | 28 | 259700 | 35728 | 79448932 |
Feeling jittery | 48.32 | 9.80 | 120 | 259608 | 12721 | 79471939 |
Blood test abnormal | 48.22 | 9.80 | 147 | 259581 | 17563 | 79467097 |
Personality disorder | 48.11 | 9.80 | 78 | 259650 | 6068 | 79478592 |
Therapeutic product ineffective | 48.06 | 9.80 | 44 | 259684 | 1878 | 79482782 |
Knee arthroplasty | 48.05 | 9.80 | 42 | 259686 | 43206 | 79441454 |
Confusional state | 48.03 | 9.80 | 1366 | 258362 | 316631 | 79168029 |
Upper gastrointestinal haemorrhage | 47.43 | 9.80 | 39 | 259689 | 41341 | 79443319 |
Gastrointestinal disorder | 47.06 | 9.80 | 221 | 259507 | 121984 | 79362676 |
Breast hyperplasia | 46.95 | 9.80 | 18 | 259710 | 136 | 79484524 |
Menstrual disorder | 46.94 | 9.80 | 62 | 259666 | 4005 | 79480655 |
Nasal polyps | 46.85 | 9.80 | 85 | 259643 | 7242 | 79477418 |
Drug screen negative | 46.67 | 9.80 | 22 | 259706 | 290 | 79484370 |
Accidental overdose | 46.53 | 9.80 | 253 | 259475 | 39328 | 79445332 |
Sleep-related eating disorder | 46.50 | 9.80 | 29 | 259699 | 685 | 79483975 |
Posture abnormal | 46.28 | 9.80 | 60 | 259668 | 3806 | 79480854 |
Depressed mood | 46.07 | 9.80 | 293 | 259435 | 48187 | 79436473 |
Housebound | 46.06 | 9.80 | 25 | 259703 | 451 | 79484209 |
Hypocalcaemia | 45.87 | 9.80 | 57 | 259671 | 49867 | 79434793 |
Rubber sensitivity | 45.62 | 9.80 | 41 | 259687 | 1708 | 79482952 |
Sluggishness | 45.57 | 9.80 | 79 | 259649 | 6493 | 79478167 |
Blister | 45.46 | 9.80 | 217 | 259511 | 119259 | 79365401 |
Tumour lysis syndrome | 45.44 | 9.80 | 11 | 259717 | 23928 | 79460732 |
Head injury | 45.38 | 9.80 | 241 | 259487 | 37128 | 79447532 |
Hypothermia | 45.30 | 9.80 | 170 | 259558 | 22576 | 79462084 |
Behaviour disorder | 45.24 | 9.80 | 77 | 259651 | 6236 | 79478424 |
Hypomagnesaemia | 44.76 | 9.80 | 52 | 259676 | 46859 | 79437801 |
Decorticate posture | 44.75 | 9.80 | 22 | 259706 | 320 | 79484340 |
Rash pruritic | 44.50 | 9.80 | 105 | 259623 | 71524 | 79413136 |
Nephrectomy | 44.48 | 9.80 | 44 | 259684 | 2071 | 79482589 |
Osteonecrosis of jaw | 44.48 | 9.80 | 45 | 259683 | 43181 | 79441479 |
Nausea | 44.45 | 9.80 | 2609 | 257119 | 954587 | 78530073 |
Neoplasm progression | 44.43 | 9.80 | 62 | 259666 | 51620 | 79433040 |
Accidental death | 44.35 | 9.80 | 62 | 259666 | 4229 | 79480431 |
Herpes zoster | 44.23 | 9.80 | 155 | 259573 | 92928 | 79391732 |
Mobility decreased | 44.13 | 9.80 | 226 | 259502 | 121949 | 79362711 |
Hypoventilation | 43.91 | 9.80 | 82 | 259646 | 7142 | 79477518 |
Hypertension | 43.87 | 9.80 | 786 | 258942 | 330206 | 79154454 |
Anaphylactic reaction | 43.55 | 9.80 | 134 | 259594 | 83609 | 79401051 |
H1N1 influenza | 43.25 | 9.80 | 47 | 259681 | 2472 | 79482188 |
Hostility | 43.01 | 9.80 | 45 | 259683 | 2265 | 79482395 |
Bronchopulmonary aspergillosis | 42.79 | 9.80 | 10 | 259718 | 22284 | 79462376 |
Ejection fraction abnormal | 42.72 | 9.80 | 46 | 259682 | 2394 | 79482266 |
Freezing phenomenon | 42.46 | 9.80 | 41 | 259687 | 1873 | 79482787 |
Screaming | 42.41 | 9.80 | 58 | 259670 | 3875 | 79480785 |
Sleep disorder due to a general medical condition | 42.19 | 9.80 | 122 | 259606 | 14155 | 79470505 |
Autonomic nervous system imbalance | 42.16 | 9.80 | 63 | 259665 | 4567 | 79480093 |
Suspected suicide | 42.10 | 9.80 | 101 | 259627 | 10475 | 79474185 |
Psoriatic arthropathy | 41.86 | 9.80 | 123 | 259605 | 77876 | 79406784 |
Atonic seizures | 41.84 | 9.80 | 28 | 259700 | 749 | 79483911 |
Plasma cell myeloma | 41.81 | 9.80 | 68 | 259660 | 53191 | 79431469 |
Cytopenia | 41.47 | 9.80 | 8 | 259720 | 20375 | 79464285 |
Stereotypy | 41.39 | 9.80 | 30 | 259698 | 915 | 79483745 |
Myocardial depression | 40.94 | 9.80 | 24 | 259704 | 505 | 79484155 |
Libido increased | 40.92 | 9.80 | 41 | 259687 | 1960 | 79482700 |
Cognitive disorder | 40.80 | 9.80 | 377 | 259351 | 69549 | 79415111 |
Acute myeloid leukaemia | 40.80 | 9.80 | 25 | 259703 | 30860 | 79453800 |
Skin ulcer | 40.79 | 9.80 | 71 | 259657 | 54079 | 79430581 |
Extrapyramidal disorder | 40.69 | 9.80 | 164 | 259564 | 22515 | 79462145 |
Cerebral haemorrhage | 40.44 | 9.80 | 79 | 259649 | 57594 | 79427066 |
Device interaction | 40.32 | 9.80 | 27 | 259701 | 723 | 79483937 |
Arthritis | 40.09 | 9.80 | 215 | 259513 | 114665 | 79369995 |
Prostate cancer | 39.84 | 9.80 | 30 | 259698 | 33238 | 79451422 |
Toxicologic test abnormal | 39.73 | 9.80 | 34 | 259694 | 1326 | 79483334 |
Hallucination, visual | 39.69 | 9.80 | 211 | 259517 | 32518 | 79452142 |
Creatinine renal clearance decreased | 39.64 | 9.80 | 7 | 259721 | 18995 | 79465665 |
Red blood cell sedimentation rate increased | 39.60 | 9.80 | 55 | 259673 | 45887 | 79438773 |
Major depression | 39.30 | 9.80 | 89 | 259639 | 8891 | 79475769 |
Antipsychotic drug level increased | 39.23 | 9.80 | 70 | 259658 | 5887 | 79478773 |
Broncholithiasis | 39.10 | 9.80 | 18 | 259710 | 224 | 79484436 |
Weight abnormal | 39.06 | 9.80 | 36 | 259692 | 1550 | 79483110 |
Bone erosion | 38.51 | 9.80 | 6 | 259722 | 17841 | 79466819 |
Shock haemorrhagic | 38.50 | 9.80 | 9 | 259719 | 20051 | 79464609 |
Product substitution issue | 38.38 | 9.80 | 149 | 259579 | 20107 | 79464553 |
Libido decreased | 38.26 | 9.80 | 65 | 259663 | 5256 | 79479404 |
Myelodysplastic syndrome | 38.02 | 9.80 | 26 | 259702 | 30275 | 79454385 |
Cerebellar atrophy | 38.00 | 9.80 | 31 | 259697 | 1130 | 79483530 |
Aspergillus infection | 37.98 | 9.80 | 8 | 259720 | 19153 | 79465507 |
Dystonic tremor | 37.62 | 9.80 | 17 | 259711 | 202 | 79484458 |
Epistaxis | 37.11 | 9.80 | 212 | 259516 | 111303 | 79373357 |
Migraine | 37.03 | 9.80 | 442 | 259286 | 87051 | 79397609 |
Paranasal sinus discomfort | 36.87 | 9.80 | 58 | 259670 | 4398 | 79480262 |
Liver disorder | 36.86 | 9.80 | 117 | 259611 | 72300 | 79412360 |
Torticollis | 36.62 | 9.80 | 42 | 259686 | 2345 | 79482315 |
Areflexia | 36.40 | 9.80 | 65 | 259663 | 5469 | 79479191 |
Tubulointerstitial nephritis | 35.82 | 9.80 | 43 | 259685 | 38192 | 79446468 |
Cerebrovascular accident | 35.36 | 9.80 | 329 | 259399 | 154963 | 79329697 |
Persecutory delusion | 35.34 | 9.80 | 60 | 259668 | 4849 | 79479811 |
Basal cell carcinoma | 35.05 | 9.80 | 42 | 259686 | 37333 | 79447327 |
Thrombotic microangiopathy | 35.04 | 9.80 | 11 | 259717 | 20158 | 79464502 |
Priapism | 35.03 | 9.80 | 57 | 259671 | 4448 | 79480212 |
Adrenal insufficiency | 35.01 | 9.80 | 25 | 259703 | 28462 | 79456198 |
Drug level above therapeutic | 34.40 | 9.80 | 83 | 259645 | 8640 | 79476020 |
Anaphylactic shock | 34.24 | 9.80 | 40 | 259688 | 35956 | 79448704 |
Vision blurred | 34.05 | 9.80 | 509 | 259219 | 105389 | 79379271 |
Adverse drug reaction | 33.98 | 9.80 | 107 | 259621 | 66285 | 79418375 |
Agoraphobia | 33.97 | 9.80 | 22 | 259706 | 556 | 79484104 |
Delirium | 33.85 | 9.80 | 423 | 259305 | 84204 | 79400456 |
Dyspnoea exertional | 33.79 | 9.80 | 157 | 259571 | 86916 | 79397744 |
Disinhibition | 33.75 | 9.80 | 42 | 259686 | 2556 | 79482104 |
Hyperthermia | 33.62 | 9.80 | 132 | 259596 | 17905 | 79466755 |
Panic disorder | 33.59 | 9.80 | 45 | 259683 | 2947 | 79481713 |
Liver injury | 33.59 | 9.80 | 85 | 259643 | 56529 | 79428131 |
Impaired driving ability | 33.58 | 9.80 | 62 | 259666 | 5353 | 79479307 |
Mutism | 33.50 | 9.80 | 40 | 259688 | 2332 | 79482328 |
Affect lability | 33.07 | 9.80 | 96 | 259632 | 11163 | 79473497 |
Pathogen resistance | 32.89 | 9.80 | 4 | 259724 | 14338 | 79470322 |
Total lung capacity increased | 32.86 | 9.80 | 39 | 259689 | 2259 | 79482401 |
Partial seizures | 32.84 | 9.80 | 83 | 259645 | 8895 | 79475765 |
Osmolar gap increased | 32.64 | 9.80 | 13 | 259715 | 110 | 79484550 |
Abdominal pain | 32.57 | 9.80 | 993 | 258735 | 388576 | 79096084 |
Fear | 32.53 | 9.80 | 150 | 259578 | 21836 | 79462824 |
Coordination abnormal | 32.52 | 9.80 | 127 | 259601 | 17185 | 79467475 |
Aplastic anaemia | 32.50 | 9.80 | 9 | 259719 | 17896 | 79466764 |
Coronary artery disease | 32.48 | 9.80 | 107 | 259621 | 65367 | 79419293 |
Decompression sickness | 32.33 | 9.80 | 12 | 259716 | 82 | 79484578 |
Incoherent | 32.30 | 9.80 | 75 | 259653 | 7617 | 79477043 |
Accidental poisoning | 32.15 | 9.80 | 33 | 259695 | 1624 | 79483036 |
Therapy non-responder | 32.07 | 9.80 | 173 | 259555 | 92132 | 79392528 |
Adjustment disorder with mixed anxiety and depressed mood | 32.04 | 9.80 | 13 | 259715 | 116 | 79484544 |
Oromandibular dystonia | 32.03 | 9.80 | 27 | 259701 | 1031 | 79483629 |
Obsessive-compulsive disorder | 32.02 | 9.80 | 64 | 259664 | 5863 | 79478797 |
Hypertonia | 32.01 | 9.80 | 72 | 259656 | 7160 | 79477500 |
Asthma | 32.00 | 9.80 | 618 | 259110 | 134477 | 79350183 |
Gaze palsy | 31.93 | 9.80 | 44 | 259684 | 2961 | 79481699 |
Encephalopathy | 31.90 | 9.80 | 348 | 259380 | 67049 | 79417611 |
Hyponatraemia | 31.58 | 9.80 | 399 | 259329 | 177449 | 79307211 |
Oedema peripheral | 31.57 | 9.80 | 605 | 259123 | 251683 | 79232977 |
Abdominal pain upper | 31.40 | 9.80 | 526 | 259202 | 223293 | 79261367 |
Haematemesis | 31.37 | 9.80 | 78 | 259650 | 52186 | 79432474 |
Psychogenic seizure | 31.37 | 9.80 | 35 | 259693 | 1896 | 79482764 |
Secretion discharge | 31.37 | 9.80 | 114 | 259614 | 14908 | 79469752 |
Withdrawal arrhythmia | 31.34 | 9.80 | 10 | 259718 | 40 | 79484620 |
Hypokalaemia | 31.16 | 9.80 | 309 | 259419 | 143731 | 79340929 |
Emotional distress | 31.11 | 9.80 | 230 | 259498 | 39739 | 79444921 |
Right ventricular failure | 31.07 | 9.80 | 19 | 259709 | 23478 | 79461182 |
Pneumonia | 30.84 | 9.80 | 1798 | 257930 | 658448 | 78826212 |
Influenza like illness | 30.67 | 9.80 | 363 | 259365 | 71344 | 79413316 |
Rapid eye movement sleep behaviour disorder | 30.54 | 9.80 | 19 | 259709 | 447 | 79484213 |
International normalised ratio increased | 30.43 | 9.80 | 157 | 259571 | 84564 | 79400096 |
Encephalitis toxic | 30.07 | 9.80 | 16 | 259712 | 277 | 79484383 |
Drug diversion | 30.06 | 9.80 | 28 | 259700 | 1222 | 79483438 |
Pleurothotonus | 30.04 | 9.80 | 39 | 259689 | 2477 | 79482183 |
Coma blister | 30.04 | 9.80 | 15 | 259713 | 226 | 79484434 |
Bruxism | 30.04 | 9.80 | 50 | 259678 | 3976 | 79480684 |
Psychiatric symptom | 29.98 | 9.80 | 69 | 259659 | 6966 | 79477694 |
Lymph node calcification | 29.96 | 9.80 | 18 | 259710 | 397 | 79484263 |
Ear congestion | 29.91 | 9.80 | 42 | 259686 | 2877 | 79481783 |
Parasomnia | 29.69 | 9.80 | 20 | 259708 | 541 | 79484119 |
Heat stroke | 29.63 | 9.80 | 32 | 259696 | 1671 | 79482989 |
Bacteraemia | 29.61 | 9.80 | 38 | 259690 | 32786 | 79451874 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 29.58 | 9.80 | 44 | 259684 | 3177 | 79481483 |
Urinary retention | 29.43 | 9.80 | 298 | 259430 | 56332 | 79428328 |
Stoma site extravasation | 29.41 | 9.80 | 17 | 259711 | 348 | 79484312 |
Treatment noncompliance | 29.09 | 9.80 | 279 | 259449 | 51989 | 79432671 |
Heart rate increased | 28.85 | 9.80 | 553 | 259175 | 120171 | 79364489 |
Stoma site hypergranulation | 28.80 | 9.80 | 18 | 259710 | 427 | 79484233 |
Hypervolaemia | 28.63 | 9.80 | 60 | 259668 | 42630 | 79442030 |
Sinus pain | 28.63 | 9.80 | 47 | 259681 | 3695 | 79480965 |
Substance use disorder | 28.53 | 9.80 | 24 | 259704 | 914 | 79483746 |
Limb injury | 28.39 | 9.80 | 179 | 259549 | 29349 | 79455311 |
Vessel puncture site erythema | 28.38 | 9.80 | 6 | 259722 | 0 | 79484660 |
Liver function test increased | 28.30 | 9.80 | 54 | 259674 | 39719 | 79444941 |
Muscle twitching | 28.24 | 9.80 | 157 | 259571 | 24607 | 79460053 |
Stoma site pain | 28.22 | 9.80 | 29 | 259699 | 1429 | 79483231 |
Rectal haemorrhage | 28.20 | 9.80 | 140 | 259588 | 76160 | 79408500 |
Cholestasis | 28.09 | 9.80 | 82 | 259646 | 52027 | 79432633 |
Feeling guilty | 28.04 | 9.80 | 23 | 259705 | 845 | 79483815 |
Diverticulitis | 28.01 | 9.80 | 68 | 259660 | 45868 | 79438792 |
Haematotoxicity | 27.80 | 9.80 | 8 | 259720 | 15511 | 79469149 |
Sinus tachycardia | 27.38 | 9.80 | 210 | 259518 | 36698 | 79447962 |
Urinary incontinence | 27.20 | 9.80 | 227 | 259501 | 40682 | 79443978 |
Impulsive behaviour | 27.18 | 9.80 | 40 | 259688 | 2860 | 79481800 |
Reduced facial expression | 27.17 | 9.80 | 39 | 259689 | 2726 | 79481934 |
Concussion | 26.93 | 9.80 | 80 | 259648 | 9423 | 79475237 |
Ehlers-Danlos syndrome | 26.90 | 9.80 | 12 | 259716 | 138 | 79484522 |
Band neutrophil percentage increased | 26.88 | 9.80 | 17 | 259711 | 412 | 79484248 |
Parosmia | 26.87 | 9.80 | 66 | 259662 | 6948 | 79477712 |
Euphoric mood | 26.78 | 9.80 | 70 | 259658 | 7656 | 79477004 |
Schizoaffective disorder | 26.70 | 9.80 | 34 | 259694 | 2118 | 79482542 |
Stress | 26.51 | 9.80 | 385 | 259343 | 79227 | 79405433 |
Somnambulism | 26.50 | 9.80 | 58 | 259670 | 5663 | 79478997 |
Coma scale abnormal | 26.46 | 9.80 | 75 | 259653 | 8603 | 79476057 |
Osteoporosis | 26.45 | 9.80 | 89 | 259639 | 54023 | 79430637 |
Respiratory rate decreased | 26.41 | 9.80 | 55 | 259673 | 5188 | 79479472 |
Wrong patient received product | 26.32 | 9.80 | 51 | 259677 | 4567 | 79480093 |
Urinary bladder rupture | 26.28 | 9.80 | 11 | 259717 | 107 | 79484553 |
Parkinsonian gait | 26.27 | 9.80 | 23 | 259705 | 925 | 79483735 |
Oropharyngeal oedema | 26.27 | 9.80 | 17 | 259711 | 429 | 79484231 |
Blood prolactin increased | 26.24 | 9.80 | 47 | 259681 | 3964 | 79480696 |
Change in seizure presentation | 26.17 | 9.80 | 18 | 259710 | 504 | 79484156 |
Blood creatine phosphokinase | 26.09 | 9.80 | 12 | 259716 | 149 | 79484511 |
Tachyphrenia | 26.03 | 9.80 | 33 | 259695 | 2047 | 79482613 |
Attention deficit hyperactivity disorder | 25.91 | 9.80 | 42 | 259686 | 3267 | 79481393 |
Ketosis-prone diabetes mellitus | 25.90 | 9.80 | 8 | 259720 | 28 | 79484632 |
Apathy | 25.85 | 9.80 | 97 | 259631 | 12880 | 79471780 |
Logorrhoea | 25.85 | 9.80 | 49 | 259679 | 4316 | 79480344 |
Fluid retention | 25.28 | 9.80 | 129 | 259599 | 69680 | 79414980 |
Pulmonary hypertension | 24.95 | 9.80 | 77 | 259651 | 48003 | 79436657 |
Upper respiratory tract infection | 24.90 | 9.80 | 184 | 259544 | 90984 | 79393676 |
Hyperkinesia | 24.66 | 9.80 | 37 | 259691 | 2692 | 79481968 |
Hypotonia | 24.65 | 9.80 | 95 | 259633 | 12775 | 79471885 |
Pain | 24.62 | 9.80 | 1966 | 257762 | 701836 | 78782824 |
Jaundice | 24.57 | 9.80 | 90 | 259638 | 53259 | 79431401 |
Drug tolerance decreased | 24.56 | 9.80 | 6 | 259722 | 12972 | 79471688 |
Poor quality sleep | 24.55 | 9.80 | 142 | 259586 | 22580 | 79462080 |
Pulmonary arterial hypertension | 24.41 | 9.80 | 34 | 259694 | 28332 | 79456328 |
Anorgasmia | 24.38 | 9.80 | 25 | 259703 | 1229 | 79483431 |
Muscle disorder | 24.35 | 9.80 | 56 | 259672 | 5651 | 79479009 |
Post-traumatic neck syndrome | 24.29 | 9.80 | 32 | 259696 | 2062 | 79482598 |
Nasal oedema | 24.23 | 9.80 | 29 | 259699 | 1695 | 79482965 |
Diffuse large B-cell lymphoma | 24.23 | 9.80 | 5 | 259723 | 12144 | 79472516 |
Bronchopulmonary aspergillosis allergic | 24.17 | 9.80 | 39 | 259689 | 3022 | 79481638 |
Hyperreflexia | 24.15 | 9.80 | 71 | 259657 | 8314 | 79476346 |
Device dislocation | 24.08 | 9.80 | 156 | 259572 | 25814 | 79458846 |
Disorganised speech | 24.01 | 9.80 | 32 | 259696 | 2085 | 79482575 |
Lymphopenia | 24.00 | 9.80 | 39 | 259689 | 30518 | 79454142 |
Haematuria | 23.92 | 9.80 | 129 | 259599 | 68707 | 79415953 |
Thrombosis | 23.81 | 9.80 | 168 | 259560 | 83932 | 79400728 |
Post-anoxic myoclonus | 23.80 | 9.80 | 8 | 259720 | 39 | 79484621 |
Squamous cell carcinoma of skin | 23.77 | 9.80 | 8 | 259720 | 14025 | 79470635 |
Nephropathy toxic | 23.71 | 9.80 | 19 | 259709 | 20400 | 79464260 |
Hyperphagia | 23.63 | 9.80 | 35 | 259693 | 2517 | 79482143 |
Panic reaction | 23.57 | 9.80 | 49 | 259679 | 4616 | 79480044 |
Impulse-control disorder | 23.56 | 9.80 | 29 | 259699 | 1745 | 79482915 |
Stupor | 23.56 | 9.80 | 62 | 259666 | 6810 | 79477850 |
Chronic kidney disease | 23.53 | 9.80 | 123 | 259605 | 66031 | 79418629 |
Disseminated intravascular coagulation | 23.51 | 9.80 | 51 | 259677 | 35791 | 79448869 |
Hepatic cirrhosis | 23.46 | 9.80 | 49 | 259679 | 34857 | 79449803 |
Lupus-like syndrome | 23.29 | 9.80 | 8 | 259720 | 13849 | 79470811 |
Lung disorder | 23.26 | 9.80 | 160 | 259568 | 80397 | 79404263 |
Brain scan abnormal | 23.09 | 9.80 | 24 | 259704 | 1199 | 79483461 |
Self-injurious ideation | 23.00 | 9.80 | 42 | 259686 | 3596 | 79481064 |
Failure to suspend medication | 22.96 | 9.80 | 16 | 259712 | 458 | 79484202 |
Aphasia | 22.90 | 9.80 | 243 | 259485 | 46489 | 79438171 |
Enthesopathy | 22.69 | 9.80 | 5 | 259723 | 11603 | 79473057 |
Postmortem blood drug level abnormal | 22.55 | 9.80 | 18 | 259710 | 636 | 79484024 |
Rash maculo-papular | 22.42 | 9.80 | 100 | 259628 | 55978 | 79428682 |
Clostridium difficile infection | 22.41 | 9.80 | 68 | 259660 | 42617 | 79442043 |
Bipolar I disorder | 22.36 | 9.80 | 31 | 259697 | 2098 | 79482562 |
Dysstasia | 22.36 | 9.80 | 161 | 259567 | 27585 | 79457075 |
Drug eruption | 22.35 | 9.80 | 71 | 259657 | 43864 | 79440796 |
Post transplant lymphoproliferative disorder | 22.29 | 9.80 | 5 | 259723 | 11459 | 79473201 |
Visceral congestion | 22.20 | 9.80 | 21 | 259707 | 935 | 79483725 |
Product use issue | 22.19 | 9.80 | 517 | 259211 | 209305 | 79275355 |
Weight increased | 22.08 | 9.80 | 1110 | 258618 | 276276 | 79208384 |
Stoma site infection | 22.08 | 9.80 | 26 | 259702 | 1494 | 79483166 |
Substance dependence | 22.07 | 9.80 | 16 | 259712 | 488 | 79484172 |
Osteoarthritis | 22.07 | 9.80 | 180 | 259548 | 87129 | 79397531 |
Post-traumatic stress disorder | 22.06 | 9.80 | 49 | 259679 | 4832 | 79479828 |
Psychotic disorder due to a general medical condition | 21.99 | 9.80 | 13 | 259715 | 278 | 79484382 |
White blood cell count decreased | 21.90 | 9.80 | 457 | 259271 | 187831 | 79296829 |
Food craving | 21.87 | 9.80 | 27 | 259701 | 1630 | 79483030 |
Cholelithiasis | 21.82 | 9.80 | 265 | 259463 | 52399 | 79432261 |
Sebaceous gland infection | 21.72 | 9.80 | 11 | 259717 | 171 | 79484489 |
Testicular infarction | 21.64 | 9.80 | 8 | 259720 | 54 | 79484606 |
Stoma site inflammation | 21.56 | 9.80 | 18 | 259710 | 678 | 79483982 |
Tinnitus | 21.48 | 9.80 | 230 | 259498 | 44103 | 79440557 |
Acute generalised exanthematous pustulosis | 21.39 | 9.80 | 15 | 259713 | 17239 | 79467421 |
Hereditary angioedema | 21.29 | 9.80 | 51 | 259677 | 5284 | 79479376 |
Leukopenia | 21.20 | 9.80 | 260 | 259468 | 116253 | 79368407 |
Suicidal behaviour | 21.18 | 9.80 | 38 | 259690 | 3209 | 79481451 |
Anion gap increased | 21.10 | 9.80 | 41 | 259687 | 3679 | 79480981 |
Live birth | 21.07 | 9.80 | 18 | 259710 | 18726 | 79465934 |
Haemophagocytic lymphohistiocytosis | 21.06 | 9.80 | 24 | 259704 | 21813 | 79462847 |
Psychotic behaviour | 21.03 | 9.80 | 22 | 259706 | 1107 | 79483553 |
Sensory loss | 21.00 | 9.80 | 91 | 259637 | 12900 | 79471760 |
Kidney transplant rejection | 20.89 | 9.80 | 4 | 259724 | 10242 | 79474418 |
Physical assault | 20.86 | 9.80 | 26 | 259702 | 1585 | 79483075 |
Clonus | 20.74 | 9.80 | 59 | 259669 | 6781 | 79477879 |
Atrial flutter | 20.60 | 9.80 | 24 | 259704 | 21601 | 79463059 |
Dysphemia | 20.50 | 9.80 | 39 | 259689 | 3445 | 79481215 |
Seizure cluster | 20.48 | 9.80 | 14 | 259714 | 388 | 79484272 |
Blood iron decreased | 20.45 | 9.80 | 102 | 259626 | 15332 | 79469328 |
Cholangitis | 20.42 | 9.80 | 8 | 259720 | 12768 | 79471892 |
Onychophagia | 20.37 | 9.80 | 9 | 259719 | 101 | 79484559 |
Soft tissue injury | 20.32 | 9.80 | 27 | 259701 | 1754 | 79482906 |
Social anxiety disorder | 20.29 | 9.80 | 16 | 259712 | 555 | 79484105 |
Graft versus host disease | 20.07 | 9.80 | 12 | 259716 | 15014 | 79469646 |
Transfusion | 19.97 | 9.80 | 24 | 259704 | 21306 | 79463354 |
Dehydration | 19.90 | 9.80 | 636 | 259092 | 247551 | 79237109 |
Haemoglobin urine | 19.89 | 9.80 | 10 | 259718 | 153 | 79484507 |
Cerebral infarction | 19.78 | 9.80 | 79 | 259649 | 45597 | 79439063 |
Postoperative respiratory failure | 19.67 | 9.80 | 11 | 259717 | 211 | 79484449 |
Compartment syndrome | 19.66 | 9.80 | 48 | 259680 | 5034 | 79479626 |
Phaeochromocytoma malignant | 19.66 | 9.80 | 8 | 259720 | 72 | 79484588 |
CADASIL | 19.63 | 9.80 | 7 | 259721 | 42 | 79484618 |
Parotid gland enlargement | 19.59 | 9.80 | 20 | 259708 | 978 | 79483682 |
Immunosuppressant drug level increased | 19.56 | 9.80 | 3 | 259725 | 9024 | 79475636 |
Pneumonitis | 19.55 | 9.80 | 117 | 259611 | 60743 | 79423917 |
Acute coronary syndrome | 19.55 | 9.80 | 24 | 259704 | 21109 | 79463551 |
Prescribed overdose | 19.52 | 9.80 | 199 | 259529 | 37684 | 79446976 |
Developmental delay | 19.46 | 9.80 | 22 | 259706 | 1209 | 79483451 |
Venoocclusive liver disease | 19.44 | 9.80 | 7 | 259721 | 11764 | 79472896 |
Ulcer | 19.37 | 9.80 | 43 | 259685 | 29929 | 79454731 |
Bladder cancer | 19.33 | 9.80 | 21 | 259707 | 19505 | 79465155 |
Staphylococcal infection | 19.30 | 9.80 | 111 | 259617 | 58184 | 79426476 |
Blood sodium decreased | 19.25 | 9.80 | 179 | 259549 | 33076 | 79451584 |
Obsessive thoughts | 19.22 | 9.80 | 21 | 259707 | 1111 | 79483549 |
Blood phosphorus increased | 19.16 | 9.80 | 5 | 259723 | 10342 | 79474318 |
Compulsive shopping | 19.09 | 9.80 | 18 | 259710 | 798 | 79483862 |
Gambling disorder | 19.07 | 9.80 | 28 | 259700 | 1998 | 79482662 |
Dysphagia | 19.05 | 9.80 | 527 | 259201 | 121609 | 79363051 |
Hypomania | 19.04 | 9.80 | 61 | 259667 | 7483 | 79477177 |
Antisocial behaviour | 19.00 | 9.80 | 17 | 259711 | 704 | 79483956 |
End stage renal disease | 18.97 | 9.80 | 8 | 259720 | 12212 | 79472448 |
Sinusitis | 18.95 | 9.80 | 488 | 259240 | 195013 | 79289647 |
Brain injury | 18.87 | 9.80 | 81 | 259647 | 11436 | 79473224 |
Metastases to liver | 18.81 | 9.80 | 40 | 259688 | 28274 | 79456386 |
Polymyalgia rheumatica | 18.79 | 9.80 | 44 | 259684 | 4493 | 79480167 |
Head titubation | 18.78 | 9.80 | 19 | 259709 | 919 | 79483741 |
Accidental exposure to product by child | 18.78 | 9.80 | 34 | 259694 | 2892 | 79481768 |
Bradycardia | 18.71 | 9.80 | 576 | 259152 | 134981 | 79349679 |
Troponin increased | 18.68 | 9.80 | 117 | 259611 | 19138 | 79465522 |
Forced expiratory volume decreased | 18.66 | 9.80 | 62 | 259666 | 7752 | 79476908 |
Aspiration | 18.64 | 9.80 | 121 | 259607 | 20037 | 79464623 |
Obsessive-compulsive personality disorder | 18.61 | 9.80 | 9 | 259719 | 126 | 79484534 |
Oculogyric crisis | 18.56 | 9.80 | 34 | 259694 | 2918 | 79481742 |
Tongue discolouration | 18.54 | 9.80 | 39 | 259689 | 3704 | 79480956 |
Blood loss anaemia | 18.53 | 9.80 | 14 | 259714 | 15484 | 79469176 |
Amylase increased | 18.49 | 9.80 | 79 | 259649 | 11130 | 79473530 |
Brain malformation | 18.36 | 9.80 | 7 | 259721 | 52 | 79484608 |
Sexual abuse | 18.29 | 9.80 | 11 | 259717 | 243 | 79484417 |
Tic | 18.28 | 9.80 | 34 | 259694 | 2952 | 79481708 |
Homicidal ideation | 18.28 | 9.80 | 37 | 259691 | 3420 | 79481240 |
Haemorrhage intracranial | 18.26 | 9.80 | 36 | 259692 | 26157 | 79458503 |
Choreoathetosis | 18.22 | 9.80 | 24 | 259704 | 1546 | 79483114 |
Intellectual disability | 18.22 | 9.80 | 22 | 259706 | 1298 | 79483362 |
Congenital inguinal hernia | 18.19 | 9.80 | 5 | 259723 | 10 | 79484650 |
Bursitis | 18.18 | 9.80 | 58 | 259670 | 35786 | 79448874 |
Pericardial effusion | 18.16 | 9.80 | 83 | 259645 | 46154 | 79438506 |
Wound complication | 18.10 | 9.80 | 46 | 259682 | 4947 | 79479713 |
Vomiting | 18.05 | 9.80 | 1896 | 257832 | 663932 | 78820728 |
Enuresis | 18.01 | 9.80 | 35 | 259693 | 3141 | 79481519 |
Therapeutic response unexpected | 18.00 | 9.80 | 119 | 259609 | 19827 | 79464833 |
Staphylococcal sepsis | 17.99 | 9.80 | 13 | 259715 | 14713 | 79469947 |
Dependence | 17.96 | 9.80 | 30 | 259698 | 2392 | 79482268 |
Angina pectoris | 17.94 | 9.80 | 97 | 259631 | 51635 | 79433025 |
Mucormycosis | 17.93 | 9.80 | 3 | 259725 | 8466 | 79476194 |
Conversion disorder | 17.92 | 9.80 | 26 | 259702 | 1835 | 79482825 |
Formication | 17.92 | 9.80 | 46 | 259682 | 4977 | 79479683 |
Purpura fulminans | 17.87 | 9.80 | 10 | 259718 | 192 | 79484468 |
Cerebral artery thrombosis | 17.81 | 9.80 | 20 | 259708 | 1091 | 79483569 |
Haemoptysis | 17.81 | 9.80 | 108 | 259620 | 55891 | 79428769 |
Muscle spasms | 17.78 | 9.80 | 717 | 259011 | 174013 | 79310647 |
Brain oedema | 17.78 | 9.80 | 142 | 259586 | 25121 | 79459539 |
Cardiac failure chronic | 17.75 | 9.80 | 7 | 259721 | 11128 | 79473532 |
Hypoxic-ischaemic encephalopathy | 17.75 | 9.80 | 61 | 259667 | 7759 | 79476901 |
Conduction disorder | 17.67 | 9.80 | 36 | 259692 | 3343 | 79481317 |
Liver function test abnormal | 17.67 | 9.80 | 130 | 259598 | 64345 | 79420315 |
Hyperchloraemia | 17.67 | 9.80 | 20 | 259708 | 1101 | 79483559 |
Muscle contracture | 17.59 | 9.80 | 29 | 259699 | 2288 | 79482372 |
Rhabdomyolysis | 17.52 | 9.80 | 450 | 259278 | 102681 | 79381979 |
Flat affect | 17.49 | 9.80 | 27 | 259701 | 2014 | 79482646 |
Wrist fracture | 17.39 | 9.80 | 81 | 259647 | 11840 | 79472820 |
Cardiac disorder | 17.37 | 9.80 | 306 | 259422 | 65451 | 79419209 |
COVID-19 pneumonia | 17.35 | 9.80 | 43 | 259685 | 28806 | 79455854 |
Hyperglycaemia | 17.33 | 9.80 | 146 | 259582 | 70189 | 79414471 |
Physical abuse | 17.26 | 9.80 | 6 | 259722 | 33 | 79484627 |
Heart rate abnormal | 17.17 | 9.80 | 51 | 259677 | 6006 | 79478654 |
Neglect of personal appearance | 17.11 | 9.80 | 9 | 259719 | 152 | 79484508 |
Substance use | 17.04 | 9.80 | 18 | 259710 | 916 | 79483744 |
Infantile spasms | 17.02 | 9.80 | 11 | 259717 | 277 | 79484383 |
Hypersexuality | 16.96 | 9.80 | 24 | 259704 | 1656 | 79483004 |
Haematoma | 16.95 | 9.80 | 100 | 259628 | 52095 | 79432565 |
Breast cancer stage II | 16.92 | 9.80 | 3 | 259725 | 8117 | 79476543 |
Gastrointestinal toxicity | 16.89 | 9.80 | 3 | 259725 | 8106 | 79476554 |
Hyperbilirubinaemia | 16.83 | 9.80 | 34 | 259694 | 24484 | 79460176 |
HIV peripheral neuropathy | 16.82 | 9.80 | 6 | 259722 | 36 | 79484624 |
Exposure during pregnancy | 16.80 | 9.80 | 230 | 259498 | 100902 | 79383758 |
BK virus infection | 16.80 | 9.80 | 4 | 259724 | 8800 | 79475860 |
Colitis microscopic | 16.79 | 9.80 | 7 | 259721 | 10761 | 79473899 |
Oedema | 16.77 | 9.80 | 281 | 259447 | 119299 | 79365361 |
Excessive eye blinking | 16.73 | 9.80 | 24 | 259704 | 1677 | 79482983 |
Blood cholesterol increased | 16.71 | 9.80 | 183 | 259545 | 83537 | 79401123 |
Niemann-Pick disease | 16.55 | 9.80 | 6 | 259722 | 38 | 79484622 |
Anticonvulsant drug level below therapeutic | 16.55 | 9.80 | 19 | 259709 | 1062 | 79483598 |
Nail disorder | 16.50 | 9.80 | 9 | 259719 | 11843 | 79472817 |
Decreased appetite | 16.38 | 9.80 | 930 | 258798 | 341488 | 79143172 |
Illusion | 16.30 | 9.80 | 24 | 259704 | 1717 | 79482943 |
Nephrotic syndrome | 16.28 | 9.80 | 8 | 259720 | 11166 | 79473494 |
Hyperammonaemic encephalopathy | 16.24 | 9.80 | 43 | 259685 | 4739 | 79479921 |
Myelocyte count increased | 16.18 | 9.80 | 16 | 259712 | 753 | 79483907 |
Sudden unexplained death in epilepsy | 16.14 | 9.80 | 15 | 259713 | 653 | 79484007 |
Lip and/or oral cavity cancer | 16.10 | 9.80 | 19 | 259709 | 1094 | 79483566 |
Social avoidant behaviour | 16.06 | 9.80 | 43 | 259685 | 4771 | 79479889 |
Blood uric acid increased | 16.06 | 9.80 | 12 | 259716 | 13348 | 79471312 |
Labelled drug-drug interaction medication error | 16.03 | 9.80 | 42 | 259686 | 27608 | 79457052 |
Petit mal epilepsy | 16.02 | 9.80 | 48 | 259680 | 5679 | 79478981 |
Epstein-Barr virus infection | 16.01 | 9.80 | 14 | 259714 | 14402 | 79470258 |
Generalised anxiety disorder | 16.01 | 9.80 | 27 | 259701 | 2170 | 79482490 |
Paralysis | 16.01 | 9.80 | 85 | 259643 | 13092 | 79471568 |
Staphylococcal bacteraemia | 15.98 | 9.80 | 10 | 259718 | 12208 | 79472452 |
Escherichia sepsis | 15.97 | 9.80 | 4 | 259724 | 8504 | 79476156 |
Drug ineffective for unapproved indication | 15.97 | 9.80 | 245 | 259483 | 50993 | 79433667 |
Injection site pruritus | 15.96 | 9.80 | 77 | 259651 | 42206 | 79442454 |
Learning disorder | 15.95 | 9.80 | 14 | 259714 | 565 | 79484095 |
Polyarthritis | 15.95 | 9.80 | 10 | 259718 | 12192 | 79472468 |
Dysmorphism | 15.91 | 9.80 | 14 | 259714 | 567 | 79484093 |
Second primary malignancy | 15.86 | 9.80 | 14 | 259714 | 14336 | 79470324 |
Wound infection | 15.85 | 9.80 | 34 | 259694 | 23957 | 79460703 |
Allodynia | 15.84 | 9.80 | 23 | 259705 | 1625 | 79483035 |
Akinesia | 15.82 | 9.80 | 34 | 259694 | 3278 | 79481382 |
Pneumonia bacterial | 15.82 | 9.80 | 24 | 259704 | 19307 | 79465353 |
Myelocyte percentage increased | 15.75 | 9.80 | 10 | 259718 | 244 | 79484416 |
Abulia | 15.74 | 9.80 | 18 | 259710 | 1002 | 79483658 |
Band neutrophil count increased | 15.72 | 9.80 | 15 | 259713 | 675 | 79483985 |
Road traffic accident | 15.67 | 9.80 | 214 | 259514 | 43450 | 79441210 |
Sinus disorder | 15.66 | 9.80 | 126 | 259602 | 22338 | 79462322 |
Poverty of speech | 15.64 | 9.80 | 14 | 259714 | 580 | 79484080 |
Facial bones fracture | 15.57 | 9.80 | 44 | 259684 | 5038 | 79479622 |
Urosepsis | 15.54 | 9.80 | 40 | 259688 | 26455 | 79458205 |
Illness anxiety disorder | 15.50 | 9.80 | 10 | 259718 | 251 | 79484409 |
Death | 15.31 | 9.80 | 2087 | 257641 | 564427 | 78920233 |
Osteonecrosis | 15.29 | 9.80 | 51 | 259677 | 31044 | 79453616 |
Drop attacks | 15.25 | 9.80 | 18 | 259710 | 1037 | 79483623 |
Cushingoid | 15.24 | 9.80 | 6 | 259722 | 9546 | 79475114 |
Asphyxia | 15.21 | 9.80 | 77 | 259651 | 11643 | 79473017 |
Fibrous histiocytoma | 15.20 | 9.80 | 15 | 259713 | 704 | 79483956 |
Communication disorder | 15.16 | 9.80 | 38 | 259690 | 4052 | 79480608 |
Facet joint syndrome | 15.14 | 9.80 | 9 | 259719 | 11293 | 79473367 |
Subarachnoid haemorrhage | 15.08 | 9.80 | 36 | 259692 | 24429 | 79460231 |
Hypoalbuminaemia | 15.08 | 9.80 | 29 | 259699 | 21268 | 79463392 |
Mouth ulceration | 15.03 | 9.80 | 69 | 259659 | 38325 | 79446335 |
Incorrect dose administered | 15.02 | 9.80 | 341 | 259387 | 76289 | 79408371 |
Electrocardiogram QRS complex shortened | 15.01 | 9.80 | 15 | 259713 | 715 | 79483945 |
Spasmodic dysphonia | 14.93 | 9.80 | 10 | 259718 | 268 | 79484392 |
Dermatitis acneiform | 14.79 | 9.80 | 7 | 259721 | 9986 | 79474674 |
Peripheral venous disease | 14.79 | 9.80 | 18 | 259710 | 15891 | 79468769 |
Abscess | 14.77 | 9.80 | 33 | 259695 | 22918 | 79461742 |
Renal hypertension | 14.76 | 9.80 | 9 | 259719 | 204 | 79484456 |
Distractibility | 14.75 | 9.80 | 15 | 259713 | 730 | 79483930 |
Respiratory dyskinesia | 14.74 | 9.80 | 6 | 259722 | 54 | 79484606 |
Sleep talking | 14.69 | 9.80 | 18 | 259710 | 1078 | 79483582 |
Intentional product use issue | 14.66 | 9.80 | 380 | 259348 | 151732 | 79332928 |
Hepatic cancer | 14.65 | 9.80 | 8 | 259720 | 10521 | 79474139 |
Rash erythematous | 14.65 | 9.80 | 119 | 259609 | 57650 | 79427010 |
Drug-induced liver injury | 14.64 | 9.80 | 141 | 259587 | 65976 | 79418684 |
Pancreatitis acute | 14.58 | 9.80 | 98 | 259630 | 49506 | 79435154 |
Tonic convulsion | 14.51 | 9.80 | 26 | 259702 | 2194 | 79482466 |
Peroneal nerve palsy | 14.48 | 9.80 | 48 | 259680 | 5994 | 79478666 |
Colitis ulcerative | 14.47 | 9.80 | 61 | 259667 | 34681 | 79449979 |
Dermatitis exfoliative generalised | 14.40 | 9.80 | 3 | 259725 | 7238 | 79477422 |
Feeling cold | 14.37 | 9.80 | 150 | 259578 | 28579 | 79456081 |
Erythema multiforme | 14.36 | 9.80 | 22 | 259706 | 17629 | 79467031 |
Postictal paralysis | 14.27 | 9.80 | 11 | 259717 | 369 | 79484291 |
Organising pneumonia | 14.25 | 9.80 | 9 | 259719 | 10930 | 79473730 |
Cystitis haemorrhagic | 14.24 | 9.80 | 6 | 259722 | 9166 | 79475494 |
Obstructive airways disorder | 14.23 | 9.80 | 161 | 259567 | 31298 | 79453362 |
Autoimmune disorder | 14.20 | 9.80 | 20 | 259708 | 16592 | 79468068 |
Lower gastrointestinal haemorrhage | 14.20 | 9.80 | 19 | 259709 | 16106 | 79468554 |
Sensorimotor disorder | 14.17 | 9.80 | 16 | 259712 | 878 | 79483782 |
Erectile dysfunction | 14.16 | 9.80 | 89 | 259639 | 14575 | 79470085 |
Incorrect route of product administration | 14.14 | 9.80 | 175 | 259553 | 34754 | 79449906 |
Inappropriate affect | 14.13 | 9.80 | 21 | 259707 | 1515 | 79483145 |
Alcohol abuse | 14.12 | 9.80 | 44 | 259684 | 5319 | 79479341 |
Antidepressant drug level above therapeutic | 14.10 | 9.80 | 14 | 259714 | 662 | 79483998 |
Gastrointestinal hypomotility | 14.05 | 9.80 | 24 | 259704 | 1949 | 79482711 |
Hyperarousal | 14.02 | 9.80 | 5 | 259723 | 30 | 79484630 |
Heparin-induced thrombocytopenia | 14.00 | 9.80 | 7 | 259721 | 9675 | 79474985 |
Choking | 13.98 | 9.80 | 77 | 259651 | 12024 | 79472636 |
Cataract | 13.96 | 9.80 | 132 | 259596 | 61988 | 79422672 |
Breath holding | 13.85 | 9.80 | 6 | 259722 | 64 | 79484596 |
Mental disability | 13.85 | 9.80 | 6 | 259722 | 64 | 79484596 |
Lip dry | 13.75 | 9.80 | 18 | 259710 | 15400 | 79469260 |
Postmortem blood drug level increased | 13.72 | 9.80 | 15 | 259713 | 794 | 79483866 |
Metastases to central nervous system | 13.72 | 9.80 | 20 | 259708 | 16355 | 79468305 |
Skin toxicity | 13.63 | 9.80 | 5 | 259723 | 8309 | 79476351 |
Autoimmune hepatitis | 13.63 | 9.80 | 11 | 259717 | 11772 | 79472888 |
Oral candidiasis | 13.63 | 9.80 | 50 | 259678 | 29578 | 79455082 |
Piloerection | 13.55 | 9.80 | 12 | 259716 | 490 | 79484170 |
Patient uncooperative | 13.46 | 9.80 | 14 | 259714 | 700 | 79483960 |
Respiratory acidosis | 13.44 | 9.80 | 72 | 259656 | 11128 | 79473532 |
Dysgraphia | 13.44 | 9.80 | 36 | 259692 | 3996 | 79480664 |
Dry skin | 13.42 | 9.80 | 149 | 259579 | 67846 | 79416814 |
Locomotive syndrome | 13.42 | 9.80 | 4 | 259724 | 12 | 79484648 |
Dysmetria | 13.41 | 9.80 | 17 | 259711 | 1054 | 79483606 |
Jealous delusion | 13.38 | 9.80 | 10 | 259718 | 320 | 79484340 |
Renal disorder | 13.38 | 9.80 | 202 | 259526 | 41903 | 79442757 |
Lymphadenopathy | 13.35 | 9.80 | 110 | 259618 | 53137 | 79431523 |
Cyanosis | 13.32 | 9.80 | 133 | 259595 | 25049 | 79459611 |
Gout | 13.30 | 9.80 | 39 | 259689 | 24710 | 79459950 |
Affective disorder | 13.24 | 9.80 | 58 | 259670 | 8261 | 79476399 |
Flank pain | 13.21 | 9.80 | 28 | 259700 | 19816 | 79464844 |
Terminal insomnia | 13.20 | 9.80 | 18 | 259710 | 1199 | 79483461 |
Blood bicarbonate decreased | 13.13 | 9.80 | 42 | 259686 | 5149 | 79479511 |
Increased appetite | 13.04 | 9.80 | 75 | 259653 | 11903 | 79472757 |
Enteritis | 13.03 | 9.80 | 17 | 259711 | 14566 | 79470094 |
Glossopharyngeal nerve disorder | 13.02 | 9.80 | 5 | 259723 | 38 | 79484622 |
Bacterial infection | 12.98 | 9.80 | 55 | 259673 | 31225 | 79453435 |
Wound secretion | 12.95 | 9.80 | 47 | 259681 | 6141 | 79478519 |
Metabolic syndrome | 12.94 | 9.80 | 28 | 259700 | 2712 | 79481948 |
Retinal detachment | 12.90 | 9.80 | 7 | 259721 | 9240 | 79475420 |
Pneumothorax | 12.89 | 9.80 | 48 | 259680 | 28275 | 79456385 |
Systemic candida | 12.89 | 9.80 | 3 | 259725 | 6703 | 79477957 |
Partial seizures with secondary generalisation | 12.86 | 9.80 | 13 | 259715 | 628 | 79484032 |
Haematuria traumatic | 12.83 | 9.80 | 8 | 259720 | 189 | 79484471 |
Haemorrhage | 12.81 | 9.80 | 214 | 259514 | 90904 | 79393756 |
Cluster headache | 12.78 | 9.80 | 16 | 259712 | 980 | 79483680 |
Duodenal ulcer | 12.75 | 9.80 | 21 | 259707 | 16348 | 79468312 |
Urticaria thermal | 12.74 | 9.80 | 11 | 259717 | 434 | 79484226 |
Laryngomalacia | 12.74 | 9.80 | 4 | 259724 | 15 | 79484645 |
Uveitis | 12.73 | 9.80 | 22 | 259706 | 16808 | 79467852 |
Localised infection | 12.73 | 9.80 | 71 | 259657 | 37504 | 79447156 |
Cardiac infection | 12.72 | 9.80 | 11 | 259717 | 435 | 79484225 |
Barotrauma | 12.72 | 9.80 | 8 | 259720 | 192 | 79484468 |
Drug tolerance | 12.70 | 9.80 | 59 | 259669 | 8616 | 79476044 |
Bulbar palsy | 12.69 | 9.80 | 9 | 259719 | 265 | 79484395 |
Gastric ulcer | 12.65 | 9.80 | 62 | 259666 | 33843 | 79450817 |
Condition aggravated | 12.63 | 9.80 | 1434 | 258294 | 499690 | 78984970 |
Antidepressant drug level increased | 12.60 | 9.80 | 11 | 259717 | 441 | 79484219 |
Oral pain | 12.53 | 9.80 | 57 | 259671 | 31741 | 79452919 |
Drug level increased | 12.51 | 9.80 | 190 | 259538 | 39461 | 79445199 |
Full blood count decreased | 12.51 | 9.80 | 45 | 259683 | 26774 | 79457886 |
Stoma site irritation | 12.49 | 9.80 | 9 | 259719 | 272 | 79484388 |
Escherichia bacteraemia | 12.48 | 9.80 | 3 | 259725 | 6559 | 79478101 |
Hyperuricaemia | 12.46 | 9.80 | 12 | 259716 | 11787 | 79472873 |
Pulmonary tuberculosis | 12.45 | 9.80 | 5 | 259723 | 7860 | 79476800 |
Anticonvulsant drug level increased | 12.40 | 9.80 | 27 | 259701 | 2626 | 79482034 |
Deformity | 12.38 | 9.80 | 8 | 259720 | 9597 | 79475063 |
Escherichia infection | 12.35 | 9.80 | 25 | 259703 | 17992 | 79466668 |
Administration site erythema | 12.34 | 9.80 | 10 | 259718 | 361 | 79484299 |
Left ventricular dysfunction | 12.33 | 9.80 | 28 | 259700 | 19333 | 79465327 |
Helplessness | 12.32 | 9.80 | 10 | 259718 | 362 | 79484298 |
Pneumonia fungal | 12.32 | 9.80 | 11 | 259717 | 11199 | 79473461 |
Pupillary reflex impaired | 12.27 | 9.80 | 31 | 259697 | 3322 | 79481338 |
Pollakiuria | 12.23 | 9.80 | 180 | 259548 | 37137 | 79447523 |
Metabolic acidosis | 12.21 | 9.80 | 192 | 259536 | 82337 | 79402323 |
Tenderness | 12.17 | 9.80 | 38 | 259690 | 23604 | 79461056 |
Chemical burn of gastrointestinal tract | 12.12 | 9.80 | 3 | 259725 | 3 | 79484657 |
Eye movement disorder | 12.11 | 9.80 | 55 | 259673 | 7956 | 79476704 |
Petechiae | 12.10 | 9.80 | 31 | 259697 | 20534 | 79464126 |
Medication error | 12.10 | 9.80 | 301 | 259427 | 68341 | 79416319 |
Grip strength decreased | 12.09 | 9.80 | 34 | 259694 | 21835 | 79462825 |
Language disorder | 12.06 | 9.80 | 30 | 259698 | 3184 | 79481476 |
Gastrointestinal procedural complication | 12.05 | 9.80 | 8 | 259720 | 211 | 79484449 |
Night sweats | 12.01 | 9.80 | 110 | 259618 | 51985 | 79432675 |
Breath sounds abnormal | 12.00 | 9.80 | 21 | 259707 | 15963 | 79468697 |
Candida infection | 11.99 | 9.80 | 74 | 259654 | 38140 | 79446520 |
Sensitivity to weather change | 11.98 | 9.80 | 55 | 259673 | 7992 | 79476668 |
Cataplexy | 11.98 | 9.80 | 15 | 259713 | 919 | 79483741 |
Acute respiratory failure | 11.94 | 9.80 | 130 | 259598 | 59411 | 79425249 |
Immunodeficiency | 11.92 | 9.80 | 34 | 259694 | 21734 | 79462926 |
Cerebral atrophy | 11.88 | 9.80 | 55 | 259673 | 8020 | 79476640 |
Blepharospasm | 11.88 | 9.80 | 44 | 259684 | 5807 | 79478853 |
Therapy interrupted | 11.87 | 9.80 | 57 | 259671 | 31284 | 79453376 |
Dissociative disorder | 11.85 | 9.80 | 14 | 259714 | 807 | 79483853 |
Trismus | 11.85 | 9.80 | 42 | 259686 | 5425 | 79479235 |
Optic nerve operation | 11.83 | 9.80 | 11 | 259717 | 479 | 79484181 |
Intensive care unit acquired weakness | 11.82 | 9.80 | 22 | 259706 | 1911 | 79482749 |
Vagal nerve stimulator implantation | 11.82 | 9.80 | 4 | 259724 | 20 | 79484640 |
Anticonvulsant drug level decreased | 11.81 | 9.80 | 22 | 259706 | 1912 | 79482748 |
Blood pressure fluctuation | 11.77 | 9.80 | 151 | 259577 | 66994 | 79417666 |
Feeling drunk | 11.77 | 9.80 | 38 | 259690 | 4681 | 79479979 |
Cardiac murmur | 11.71 | 9.80 | 90 | 259638 | 15734 | 79468926 |
Pulmonary alveolar haemorrhage | 11.70 | 9.80 | 12 | 259716 | 11445 | 79473215 |
Tonic clonic movements | 11.70 | 9.80 | 24 | 259704 | 2240 | 79482420 |
Taste disorder | 11.69 | 9.80 | 21 | 259707 | 15802 | 79468858 |
Device expulsion | 11.66 | 9.80 | 44 | 259684 | 25817 | 79458843 |
Congenital knee deformity | 11.66 | 9.80 | 4 | 259724 | 21 | 79484639 |
Skin necrosis | 11.65 | 9.80 | 26 | 259702 | 18061 | 79466599 |
Anhidrosis | 11.63 | 9.80 | 8 | 259720 | 224 | 79484436 |
Polyneuropathy | 11.61 | 9.80 | 40 | 259688 | 24111 | 79460549 |
Pulmonary toxicity | 11.60 | 9.80 | 15 | 259713 | 12899 | 79471761 |
Hypnopompic hallucination | 11.59 | 9.80 | 6 | 259722 | 98 | 79484562 |
Peripheral pulse decreased | 11.57 | 9.80 | 5 | 259723 | 53 | 79484607 |
Injection site erythema | 11.54 | 9.80 | 182 | 259546 | 78015 | 79406645 |
Scrotal infection | 11.52 | 9.80 | 12 | 259716 | 601 | 79484059 |
Medical device site erosion | 11.49 | 9.80 | 5 | 259723 | 54 | 79484606 |
Binge eating | 11.47 | 9.80 | 11 | 259717 | 498 | 79484162 |
Lip swelling | 11.44 | 9.80 | 82 | 259646 | 40829 | 79443831 |
Fear of injection | 11.43 | 9.80 | 5 | 259723 | 7469 | 79477191 |
Snoring | 11.42 | 9.80 | 42 | 259686 | 5524 | 79479136 |
Metastases to bone | 11.38 | 9.80 | 41 | 259687 | 24386 | 79460274 |
Fatigue | 11.37 | 9.80 | 2771 | 256957 | 926956 | 78557704 |
Eye pruritus | 11.35 | 9.80 | 32 | 259696 | 20538 | 79464122 |
Delusion of replacement | 11.35 | 9.80 | 7 | 259721 | 162 | 79484498 |
Abdominal pain lower | 11.35 | 9.80 | 59 | 259669 | 31723 | 79452937 |
Focal dyscognitive seizures | 11.35 | 9.80 | 31 | 259697 | 3481 | 79481179 |
Vertigo | 11.32 | 9.80 | 300 | 259428 | 68782 | 79415878 |
Alcohol poisoning | 11.29 | 9.80 | 38 | 259690 | 4783 | 79479877 |
Hypothyroidism | 11.18 | 9.80 | 236 | 259492 | 52156 | 79432504 |
Urine oxalate increased | 11.12 | 9.80 | 8 | 259720 | 241 | 79484419 |
Sputum discoloured | 11.10 | 9.80 | 114 | 259614 | 21629 | 79463031 |
Gastric haemorrhage | 11.09 | 9.80 | 20 | 259708 | 15030 | 79469630 |
Tooth injury | 11.08 | 9.80 | 22 | 259706 | 2006 | 79482654 |
Product complaint | 11.07 | 9.80 | 78 | 259650 | 13271 | 79471389 |
Dissociative identity disorder | 11.02 | 9.80 | 5 | 259723 | 60 | 79484600 |
Motor dysfunction | 11.02 | 9.80 | 84 | 259644 | 14649 | 79470011 |
Sternal fracture | 10.99 | 9.80 | 25 | 259703 | 2505 | 79482155 |
Metastases to lung | 10.98 | 9.80 | 27 | 259701 | 18136 | 79466524 |
Colon cancer | 10.97 | 9.80 | 19 | 259709 | 14504 | 79470156 |
Abnormal sleep-related event | 10.96 | 9.80 | 14 | 259714 | 875 | 79483785 |
Ejaculation disorder | 10.94 | 9.80 | 11 | 259717 | 528 | 79484132 |
Decubitus ulcer | 10.94 | 9.80 | 88 | 259640 | 15599 | 79469061 |
Asterixis | 10.94 | 9.80 | 26 | 259702 | 2681 | 79481979 |
Anal spasm | 10.91 | 9.80 | 3 | 259725 | 6 | 79484654 |
Poor feeding infant | 10.91 | 9.80 | 7 | 259721 | 174 | 79484486 |
Drug specific antibody present | 10.91 | 9.80 | 4 | 259724 | 6648 | 79478012 |
Periorbital swelling | 10.83 | 9.80 | 27 | 259701 | 2869 | 79481791 |
Postmortem blood drug level | 10.78 | 9.80 | 9 | 259719 | 339 | 79484321 |
Circulatory collapse | 10.78 | 9.80 | 75 | 259653 | 37593 | 79447067 |
Homeless | 10.78 | 9.80 | 6 | 259722 | 114 | 79484546 |
Vulvovaginal mycotic infection | 10.70 | 9.80 | 36 | 259692 | 4530 | 79480130 |
Apnoea | 10.67 | 9.80 | 70 | 259658 | 11634 | 79473026 |
Gastrooesophageal reflux disease | 10.65 | 9.80 | 428 | 259300 | 103818 | 79380842 |
Faeces soft | 10.63 | 9.80 | 7 | 259721 | 8316 | 79476344 |
Infected bite | 10.62 | 9.80 | 21 | 259707 | 1909 | 79482751 |
Peritonitis | 10.61 | 9.80 | 51 | 259677 | 27985 | 79456675 |
Stoma site pruritus | 10.60 | 9.80 | 3 | 259725 | 7 | 79484653 |
Periorbital haemorrhage | 10.52 | 9.80 | 8 | 259720 | 263 | 79484397 |
Hepatic function abnormal | 10.51 | 9.80 | 171 | 259557 | 72936 | 79411724 |
Panniculitis | 10.47 | 9.80 | 15 | 259713 | 12356 | 79472304 |
Device use error | 10.47 | 9.80 | 5 | 259723 | 7096 | 79477564 |
Nodal rhythm | 10.46 | 9.80 | 28 | 259700 | 3107 | 79481553 |
Myositis | 10.45 | 9.80 | 30 | 259698 | 19138 | 79465522 |
Bladder dilatation | 10.41 | 9.80 | 22 | 259706 | 2097 | 79482563 |
Antisocial personality disorder | 10.40 | 9.80 | 5 | 259723 | 69 | 79484591 |
Pain in jaw | 10.40 | 9.80 | 98 | 259630 | 46053 | 79438607 |
Ammonia abnormal | 10.34 | 9.80 | 7 | 259721 | 191 | 79484469 |
Cardiac tamponade | 10.31 | 9.80 | 9 | 259719 | 9267 | 79475393 |
Rapid eye movements sleep abnormal | 10.31 | 9.80 | 8 | 259720 | 271 | 79484389 |
Narcotic bowel syndrome | 10.29 | 9.80 | 8 | 259720 | 272 | 79484388 |
Personal relationship issue | 10.27 | 9.80 | 7 | 259721 | 193 | 79484467 |
Cytomegalovirus infection reactivation | 10.26 | 9.80 | 8 | 259720 | 8708 | 79475952 |
Monocyte percentage increased | 10.25 | 9.80 | 22 | 259706 | 2119 | 79482541 |
Pneumatosis intestinalis | 10.23 | 9.80 | 4 | 259724 | 6393 | 79478267 |
Injection site swelling | 10.23 | 9.80 | 101 | 259627 | 47031 | 79437629 |
Alcoholism | 10.23 | 9.80 | 31 | 259697 | 3692 | 79480968 |
Nervous system disorder | 10.21 | 9.80 | 133 | 259595 | 26723 | 79457937 |
Hyperphosphataemia | 10.18 | 9.80 | 4 | 259724 | 6372 | 79478288 |
Mucosal erosion | 10.17 | 9.80 | 23 | 259705 | 2295 | 79482365 |
Neutrophil percentage increased | 10.14 | 9.80 | 36 | 259692 | 4653 | 79480007 |
Brain death | 10.14 | 9.80 | 41 | 259687 | 5636 | 79479024 |
SARS-CoV-2 test positive | 10.12 | 9.80 | 14 | 259714 | 11702 | 79472958 |
Premature labour | 10.11 | 9.80 | 54 | 259674 | 8336 | 79476324 |
Cellulitis | 10.10 | 9.80 | 274 | 259454 | 108786 | 79375874 |
Sexual dysfunction | 10.07 | 9.80 | 51 | 259677 | 7712 | 79476948 |
Therapeutic response decreased | 10.07 | 9.80 | 155 | 259573 | 66698 | 79417962 |
Tachycardia | 10.04 | 9.80 | 690 | 259038 | 177078 | 79307582 |
Radial nerve palsy | 10.03 | 9.80 | 10 | 259718 | 475 | 79484185 |
Initial insomnia | 10.02 | 9.80 | 47 | 259681 | 6891 | 79477769 |
Gastric cancer | 10.02 | 9.80 | 11 | 259717 | 10168 | 79474492 |
Drug screen false positive | 9.97 | 9.80 | 15 | 259713 | 1094 | 79483566 |
Somatic delusion | 9.96 | 9.80 | 12 | 259716 | 706 | 79483954 |
Joint effusion | 9.96 | 9.80 | 28 | 259700 | 17986 | 79466674 |
Embolism | 9.93 | 9.80 | 19 | 259709 | 13963 | 79470697 |
Dementia with Lewy bodies | 9.92 | 9.80 | 13 | 259715 | 833 | 79483827 |
Vasculitis | 9.89 | 9.80 | 45 | 259683 | 25057 | 79459603 |
Adjustment disorder with depressed mood | 9.88 | 9.80 | 9 | 259719 | 9077 | 79475583 |
Impaired self-care | 9.87 | 9.80 | 25 | 259703 | 2682 | 79481978 |
Bronchiectasis | 9.87 | 9.80 | 114 | 259614 | 22272 | 79462388 |
Diabetes mellitus inadequate control | 9.86 | 9.80 | 43 | 259685 | 24221 | 79460439 |
Somatic symptom disorder | 9.85 | 9.80 | 24 | 259704 | 2513 | 79482147 |
Decreased activity | 9.83 | 9.80 | 55 | 259673 | 8639 | 79476021 |
Blunted affect | 9.83 | 9.80 | 10 | 259718 | 487 | 79484173 |
Thrombocytosis | 9.81 | 9.80 | 8 | 259720 | 8518 | 79476142 |
Confabulation | 9.81 | 9.80 | 10 | 259718 | 488 | 79484172 |
Neuropsychiatric symptoms | 9.80 | 9.80 | 17 | 259711 | 1398 | 79483262 |
Gambling | 9.80 | 9.80 | 8 | 259720 | 292 | 79484368 |
Pre-existing condition improved | 9.80 | 9.80 | 40 | 259688 | 5523 | 79479137 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Tricuspid valve incompetence | 33.98 | 29.35 | 12 | 321 | 61 | 89398 |
Source | Code | Description |
---|---|---|
ATC | N03AE01 | NERVOUS SYSTEM ANTIEPILEPTICS ANTIEPILEPTICS Benzodiazepine derivatives |
FDA CS | M0002356 | Benzodiazepines |
CHEBI has role | CHEBI:35474 | anti-anxiety agents |
CHEBI has role | CHEBI:35623 | anticonvulsants |
CHEBI has role | CHEBI:50268 | GABA modulators |
MeSH PA | D000927 | Anticonvulsants |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D018682 | GABA Agents |
MeSH PA | D018757 | GABA Modulators |
MeSH PA | D018377 | Neurotransmitter Agents |
FDA EPC | N0000175694 | Benzodiazepine |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Myoclonic seizure | indication | 37356005 | |
Atonic seizure | indication | 42365007 | |
Absence seizure | indication | 79631006 | |
Lennox-Gastaut syndrome | indication | 230418006 | |
Panic disorder | indication | 371631005 | DOID:594 |
Akathisia | off-label use | 285145004 | |
Manic Bipolar Disorder Adjunct Treatment | off-label use | ||
Suicidal thoughts | contraindication | 6471006 | |
Alcohol intoxication | contraindication | 25702006 | |
Depressive disorder | contraindication | 35489007 | |
Hepatic failure | contraindication | 59927004 | |
Substance abuse | contraindication | 66214007 | |
Sleep apnea | contraindication | 73430006 | DOID:0050847 |
Decreased respiratory function | contraindication | 80954004 | |
Open-angle glaucoma | contraindication | 84494001 | DOID:1067 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Liver function tests abnormal | contraindication | 166603001 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Syncope | contraindication | 271594007 | |
Pregnancy, function | contraindication | 289908002 | |
At risk for aspiration | contraindication | 371736008 | |
Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
Breastfeeding (mother) | contraindication | 413712001 | |
Chronic lung disease | contraindication | 413839001 | |
Central nervous system depression | contraindication | 418072004 | |
Porphyria | contraindication | 418470004 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 10.65 | acidic |
pKa2 | 1.65 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
GABA-A receptor alpha-1/beta-2/gamma-2 | Ion channel | POSITIVE ALLOSTERIC MODULATOR | Ki | 8.07 | WOMBAT-PK | CHEMBL | |||
GABA-A receptor; anion channel | Ion channel | Ki | 9.07 | CHEMBL | |||||
GABA-A receptor; anion channel | Ion channel | IC50 | 8.77 | CHEMBL | |||||
GABA-A receptor; anion channel | Ion channel | Ki | 9.07 | CHEMBL |
ID | Source |
---|---|
4017791 | VUID |
N0000146152 | NUI |
D00280 | KEGG_DRUG |
202585 | RXNORM |
4017791 | VANDF |
C0009011 | UMLSCUI |
CHEBI:3756 | CHEBI |
CHEMBL452 | ChEMBL_ID |
DB01068 | DRUGBANK_ID |
D002998 | MESH_DESCRIPTOR_UI |
2802 | PUBCHEM_CID |
6963 | IUPHAR_LIGAND_ID |
2765 | INN_ID |
5PE9FDE8GB | UNII |
1345 | MMSL |
377 | MMSL |
4477 | MMSL |
d00197 | MMSL |
001635 | NDDF |
387383007 | SNOMEDCT_US |
69708003 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Klonopin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0004-0058 | TABLET | 1 mg | ORAL | NDA | 30 sections |
Klonopin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0004-0058 | TABLET | 1 mg | ORAL | NDA | 30 sections |
Klonopin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0004-0068 | TABLET | 0.50 mg | ORAL | NDA | 30 sections |
Klonopin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0004-0068 | TABLET | 0.50 mg | ORAL | NDA | 30 sections |
Klonopin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0004-0098 | TABLET | 2 mg | ORAL | NDA | 30 sections |
Klonopin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0004-0098 | TABLET | 2 mg | ORAL | NDA | 30 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-0832 | TABLET | 0.50 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-0832 | TABLET | 0.50 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-0832 | TABLET | 0.50 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3212 | TABLET | 1 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3212 | TABLET | 1 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3212 | TABLET | 1 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3213 | TABLET | 2 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3213 | TABLET | 2 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3213 | TABLET | 2 mg | ORAL | ANDA | 20 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9290 | TABLET, ORALLY DISINTEGRATING | 0.13 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9290 | TABLET, ORALLY DISINTEGRATING | 0.13 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9290 | TABLET, ORALLY DISINTEGRATING | 0.13 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9291 | TABLET, ORALLY DISINTEGRATING | 0.25 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9291 | TABLET, ORALLY DISINTEGRATING | 0.25 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9291 | TABLET, ORALLY DISINTEGRATING | 0.25 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9292 | TABLET, ORALLY DISINTEGRATING | 0.50 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9292 | TABLET, ORALLY DISINTEGRATING | 0.50 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9292 | TABLET, ORALLY DISINTEGRATING | 0.50 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9293 | TABLET, ORALLY DISINTEGRATING | 1 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9293 | TABLET, ORALLY DISINTEGRATING | 1 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9293 | TABLET, ORALLY DISINTEGRATING | 1 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9293 | TABLET, ORALLY DISINTEGRATING | 1 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9294 | TABLET, ORALLY DISINTEGRATING | 2 mg | ORAL | ANDA | 27 sections |
Clonazepam | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9294 | TABLET, ORALLY DISINTEGRATING | 2 mg | ORAL | ANDA | 27 sections |