cinolazepam 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diazepam derivatives 656 75696-02-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cinolazepam
  • gerodorm
  • Molecular weight: 357.77
  • Formula: C18H13ClFN3O2
  • CLOGP: 1.91
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 76.69
  • ALOGS: -4.48
  • ROTB: 3

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 95 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05CD13 NERVOUS SYSTEM
PSYCHOLEPTICS
HYPNOTICS AND SEDATIVES
Benzodiazepine derivatives
CHEBI has role CHEBI:35623 anticonvulsants
CHEBI has role CHEBI:35717 hypnotics

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.21 acidic
pKa2 1.2 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07328 KEGG_DRUG
C0164835 UMLSCUI
CHEBI:59514 CHEBI
CHEMBL2104926 ChEMBL_ID
DB01594 DRUGBANK_ID
C053781 MESH_SUPPLEMENTAL_RECORD_UI
3033621 PUBCHEM_CID
5051 INN_ID
68P0556B0U UNII

Pharmaceutical products:

None