chlorhexidine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 597 | 55-56-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 30 | mg | O |
| 30 | mg | O |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Hosey CM, Chan R, Benet LZ |
| BA (Bioavailability) | 1 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Sept. 17, 1976 | FDA | MOLNLYCKE HLTH |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Completed suicide | 3092.40 | 12.26 | 1720 | 34875 | 144200 | 46505267 |
| Toxicity to various agents | 1776.66 | 12.26 | 1402 | 35193 | 210364 | 46439103 |
| Drug abuse | 676.77 | 12.26 | 487 | 36108 | 62921 | 46586546 |
| Intentional overdose | 641.45 | 12.26 | 476 | 36119 | 64468 | 46584999 |
| Cardio-respiratory arrest | 605.11 | 12.26 | 445 | 36150 | 59424 | 46590043 |
| Suicide attempt | 398.01 | 12.26 | 336 | 36259 | 54700 | 46594767 |
| Overdose | 390.44 | 12.26 | 439 | 36156 | 101540 | 46547927 |
| Alcohol interaction | 329.49 | 12.26 | 108 | 36487 | 2337 | 46647130 |
| Lower respiratory tract infection | 257.83 | 12.26 | 264 | 36331 | 54825 | 46594642 |
| Muscle spasticity | 256.69 | 12.26 | 141 | 36454 | 11299 | 46638168 |
| Muscle injury | 224.07 | 12.26 | 98 | 36497 | 4768 | 46644699 |
| Folliculitis | 204.33 | 12.26 | 99 | 36496 | 6104 | 46643363 |
| Ear pain | 195.74 | 12.26 | 152 | 36443 | 21940 | 46627527 |
| Suspected suicide | 195.74 | 12.26 | 88 | 36507 | 4573 | 46644894 |
| Alcohol poisoning | 188.96 | 12.26 | 70 | 36525 | 2198 | 46647269 |
| Body temperature increased | 175.85 | 12.26 | 150 | 36445 | 24711 | 46624756 |
| Alcohol use | 159.08 | 12.26 | 63 | 36532 | 2379 | 46647088 |
| Respiratory disorder | 155.97 | 12.26 | 146 | 36449 | 27154 | 46622313 |
| Sleep disorder due to general medical condition, insomnia type | 155.68 | 12.26 | 78 | 36517 | 5171 | 46644296 |
| Night sweats | 150.45 | 12.26 | 143 | 36452 | 27107 | 46622360 |
| Respiratory arrest | 143.70 | 12.26 | 154 | 36441 | 33662 | 46615805 |
| Intentional product misuse | 137.54 | 12.26 | 177 | 36418 | 46951 | 46602516 |
| Drug ineffective | 134.50 | 12.26 | 203 | 36392 | 677635 | 45971832 |
| Alcohol abuse | 127.53 | 12.26 | 52 | 36543 | 2120 | 46647347 |
| Irritable bowel syndrome | 119.54 | 12.26 | 101 | 36494 | 16414 | 46633053 |
| Application site rash | 112.41 | 12.26 | 50 | 36545 | 2532 | 46646935 |
| Ill-defined disorder | 103.25 | 12.26 | 116 | 36479 | 26711 | 46622756 |
| Cardiac arrest | 101.55 | 12.26 | 221 | 36374 | 90178 | 46559289 |
| Peripheral swelling | 95.01 | 12.26 | 306 | 36289 | 157765 | 46491702 |
| Sinusitis | 93.73 | 12.26 | 268 | 36327 | 129500 | 46519967 |
| Chemical burn | 88.16 | 12.26 | 25 | 36570 | 324 | 46649143 |
| Postoperative wound infection | 81.38 | 12.26 | 62 | 36533 | 8691 | 46640776 |
| Coma | 78.86 | 12.26 | 154 | 36441 | 58195 | 46591272 |
| Impaired healing | 75.91 | 12.26 | 117 | 36478 | 36626 | 46612841 |
| Blister | 73.14 | 12.26 | 128 | 36467 | 44503 | 46604964 |
| Somnolence | 68.35 | 12.26 | 273 | 36322 | 156248 | 46493219 |
| Nausea | 68.18 | 12.26 | 293 | 36302 | 687161 | 45962306 |
| Pruritus | 65.74 | 12.26 | 368 | 36227 | 241984 | 46407483 |
| Urticaria | 65.21 | 12.26 | 222 | 36373 | 117670 | 46531797 |
| Joint swelling | 64.17 | 12.26 | 279 | 36316 | 165794 | 46483673 |
| Blood alcohol increased | 61.99 | 12.26 | 23 | 36572 | 725 | 46648742 |
| Product dose omission issue | 57.77 | 12.26 | 30 | 36565 | 168490 | 46480977 |
| Rheumatoid arthritis | 56.53 | 12.26 | 63 | 36532 | 240152 | 46409315 |
| Fall | 55.37 | 12.26 | 109 | 36486 | 328988 | 46320479 |
| Alcoholism | 54.36 | 12.26 | 29 | 36566 | 2189 | 46647278 |
| Cough | 49.28 | 12.26 | 65 | 36530 | 230184 | 46419283 |
| Exposure to toxic agent | 48.43 | 12.26 | 26 | 36569 | 1988 | 46647479 |
| Poisoning deliberate | 48.37 | 12.26 | 44 | 36551 | 7882 | 46641585 |
| Ejection fraction | 48.32 | 12.26 | 18 | 36577 | 574 | 46648893 |
| Product package associated injury | 46.94 | 12.26 | 9 | 36586 | 14 | 46649453 |
| Administration site rash | 45.63 | 12.26 | 11 | 36584 | 71 | 46649396 |
| Dermatitis contact | 45.52 | 12.26 | 43 | 36552 | 8080 | 46641387 |
| Insomnia | 44.35 | 12.26 | 250 | 36345 | 164674 | 46484793 |
| Substance abuse | 44.30 | 12.26 | 32 | 36563 | 4135 | 46645332 |
| Stomatitis | 43.49 | 12.26 | 135 | 36460 | 68162 | 46581305 |
| Mydriasis | 42.94 | 12.26 | 47 | 36548 | 10506 | 46638961 |
| Victim of sexual abuse | 42.32 | 12.26 | 16 | 36579 | 532 | 46648935 |
| Dizziness | 42.18 | 12.26 | 132 | 36463 | 340282 | 46309185 |
| Injection site pain | 39.90 | 12.26 | 17 | 36578 | 107135 | 46542332 |
| Urticaria thermal | 39.08 | 12.26 | 10 | 36585 | 85 | 46649382 |
| Condition aggravated | 38.77 | 12.26 | 84 | 36511 | 244968 | 46404499 |
| Postmortem blood drug level abnormal | 38.26 | 12.26 | 13 | 36582 | 315 | 46649152 |
| Aggression | 38.25 | 12.26 | 66 | 36529 | 22678 | 46626789 |
| Cardiac failure congestive | 35.05 | 12.26 | 14 | 36581 | 91736 | 46557731 |
| Myocardial infarction | 33.94 | 12.26 | 17 | 36578 | 97511 | 46551956 |
| Gastrointestinal disorder | 33.61 | 12.26 | 113 | 36482 | 59463 | 46590004 |
| General physical health deterioration | 33.58 | 12.26 | 25 | 36570 | 115744 | 46533723 |
| Psoriasis | 33.47 | 12.26 | 10 | 36585 | 78594 | 46570873 |
| Application site erythema | 33.46 | 12.26 | 29 | 36566 | 4875 | 46644592 |
| Anaemia | 33.21 | 12.26 | 97 | 36498 | 255682 | 46393785 |
| Asthma | 31.79 | 12.26 | 16 | 36579 | 91526 | 46557941 |
| Off label use | 31.58 | 12.26 | 172 | 36423 | 379669 | 46269798 |
| Loss of personal independence in daily activities | 31.18 | 12.26 | 4 | 36591 | 57179 | 46592288 |
| Intentional self-injury | 30.48 | 12.26 | 62 | 36533 | 24104 | 46625363 |
| Loss of consciousness | 30.35 | 12.26 | 166 | 36429 | 108072 | 46541395 |
| Asthenopia | 30.27 | 12.26 | 19 | 36576 | 1947 | 46647520 |
| Dehydration | 30.23 | 12.26 | 49 | 36546 | 159491 | 46489976 |
| Occupational exposure to product | 29.99 | 12.26 | 18 | 36577 | 1703 | 46647764 |
| Osteonecrosis of jaw | 29.75 | 12.26 | 76 | 36519 | 34326 | 46615141 |
| Malaise | 29.19 | 12.26 | 147 | 36448 | 331085 | 46318382 |
| Burkholderia test positive | 29.08 | 12.26 | 8 | 36587 | 92 | 46649375 |
| Chest pain | 29.07 | 12.26 | 59 | 36536 | 176265 | 46473202 |
| Allergy to chemicals | 29.04 | 12.26 | 14 | 36581 | 853 | 46648614 |
| Gastrointestinal toxicity | 28.32 | 12.26 | 25 | 36570 | 4306 | 46645161 |
| Duodenal ulcer perforation | 28.08 | 12.26 | 34 | 36561 | 8468 | 46640999 |
| Cerebrovascular accident | 27.80 | 12.26 | 23 | 36572 | 101016 | 46548451 |
| Fatigue | 27.66 | 12.26 | 325 | 36270 | 608372 | 46041095 |
| Cytokine release syndrome | 27.58 | 12.26 | 29 | 36566 | 6194 | 46643273 |
| Anaphylactic reaction | 27.57 | 12.26 | 98 | 36497 | 53014 | 46596453 |
| Catheter site injury | 27.20 | 12.26 | 7 | 36588 | 61 | 46649406 |
| Muscle spasms | 27.09 | 12.26 | 34 | 36561 | 123079 | 46526388 |
| Somnambulism | 26.96 | 12.26 | 26 | 36569 | 5011 | 46644456 |
| Interstitial lung disease | 26.63 | 12.26 | 5 | 36590 | 53944 | 46595523 |
| Wound secretion | 26.58 | 12.26 | 23 | 36572 | 3857 | 46645610 |
| Decreased appetite | 26.26 | 12.26 | 72 | 36523 | 193764 | 46455703 |
| Death | 26.08 | 12.26 | 388 | 36207 | 335160 | 46314307 |
| Catheter site erythema | 26.06 | 12.26 | 23 | 36572 | 3960 | 46645507 |
| Bronchitis | 25.77 | 12.26 | 27 | 36568 | 105952 | 46543515 |
| Rash | 25.32 | 12.26 | 406 | 36189 | 356106 | 46293361 |
| Feeling abnormal | 25.03 | 12.26 | 37 | 36558 | 125023 | 46524444 |
| Catheter site rash | 24.72 | 12.26 | 12 | 36583 | 742 | 46648725 |
| Burkholderia infection | 24.61 | 12.26 | 4 | 36591 | 0 | 46649467 |
| Drug use disorder | 24.60 | 12.26 | 19 | 36576 | 2716 | 46646751 |
| Sinus tachycardia | 24.35 | 12.26 | 53 | 36542 | 21596 | 46627871 |
| Incorrect route of product administration | 24.28 | 12.26 | 45 | 36550 | 16338 | 46633129 |
| Application site irritation | 24.11 | 12.26 | 16 | 36579 | 1803 | 46647664 |
| Application site pruritus | 23.94 | 12.26 | 22 | 36573 | 3991 | 46645476 |
| Homicide | 23.89 | 12.26 | 10 | 36585 | 436 | 46649031 |
| Inappropriate schedule of product administration | 23.12 | 12.26 | 11 | 36584 | 65002 | 46584465 |
| Alopecia | 23.00 | 12.26 | 59 | 36536 | 162355 | 46487112 |
| Application site dermatitis | 22.98 | 12.26 | 8 | 36587 | 209 | 46649258 |
| Pulmonary toxicity | 22.84 | 12.26 | 23 | 36572 | 4670 | 46644797 |
| Agitation | 22.82 | 12.26 | 95 | 36500 | 55320 | 46594147 |
| Corneal defect | 22.37 | 12.26 | 4 | 36591 | 3 | 46649464 |
| Gait disturbance | 21.96 | 12.26 | 51 | 36544 | 145212 | 46504255 |
| Weight decreased | 21.89 | 12.26 | 88 | 36507 | 210761 | 46438706 |
| Chemical submission | 21.81 | 12.26 | 8 | 36587 | 244 | 46649223 |
| Abdominal pain upper | 21.72 | 12.26 | 191 | 36404 | 145114 | 46504353 |
| Injection site erythema | 21.67 | 12.26 | 16 | 36579 | 74411 | 46575056 |
| Drug dependence | 21.56 | 12.26 | 48 | 36547 | 19853 | 46629614 |
| Burkholderia cepacia complex infection | 21.54 | 12.26 | 7 | 36588 | 147 | 46649320 |
| Dysmetropsia | 21.36 | 12.26 | 6 | 36589 | 75 | 46649392 |
| Contraindicated product administered | 21.33 | 12.26 | 121 | 36474 | 79826 | 46569641 |
| Drug withdrawal syndrome | 21.14 | 12.26 | 58 | 36537 | 27326 | 46622141 |
| Leukopenia | 20.81 | 12.26 | 14 | 36581 | 68329 | 46581138 |
| Upper respiratory tract infection | 20.76 | 12.26 | 12 | 36583 | 63544 | 46585923 |
| Protein C increased | 20.67 | 12.26 | 7 | 36588 | 168 | 46649299 |
| Pyogenic granuloma | 20.40 | 12.26 | 8 | 36587 | 294 | 46649173 |
| Hepatotoxicity | 20.34 | 12.26 | 54 | 36541 | 24955 | 46624512 |
| Poisoning | 20.19 | 12.26 | 38 | 36557 | 13956 | 46635511 |
| Liver injury | 20.12 | 12.26 | 41 | 36554 | 15960 | 46633507 |
| Catheter site inflammation | 19.85 | 12.26 | 10 | 36585 | 670 | 46648797 |
| Pneumonia | 19.83 | 12.26 | 194 | 36401 | 376126 | 46273341 |
| Haemoglobin decreased | 19.71 | 12.26 | 45 | 36550 | 128904 | 46520563 |
| Myocarditis | 19.39 | 12.26 | 27 | 36568 | 7712 | 46641755 |
| Migraine | 19.19 | 12.26 | 16 | 36579 | 70010 | 46579457 |
| Substance dependence | 18.91 | 12.26 | 7 | 36588 | 219 | 46649248 |
| Application site hypersensitivity | 18.91 | 12.26 | 7 | 36588 | 219 | 46649248 |
| Product contamination microbial | 18.82 | 12.26 | 7 | 36588 | 222 | 46649245 |
| Renal failure | 18.72 | 12.26 | 38 | 36557 | 113556 | 46535911 |
| Diabetes mellitus | 18.53 | 12.26 | 8 | 36587 | 50057 | 46599410 |
| Arthritis | 18.45 | 12.26 | 20 | 36575 | 77296 | 46572171 |
| Helicobacter infection | 18.36 | 12.26 | 33 | 36562 | 11703 | 46637764 |
| Electrocardiogram QRS complex prolonged | 18.34 | 12.26 | 22 | 36573 | 5427 | 46644040 |
| Suicidal ideation | 18.23 | 12.26 | 90 | 36505 | 56292 | 46593175 |
| Tachycardia | 18.15 | 12.26 | 137 | 36458 | 99485 | 46549982 |
| Cardiac disorder | 17.92 | 12.26 | 6 | 36589 | 43852 | 46605615 |
| Blood glucose increased | 17.90 | 12.26 | 18 | 36577 | 71995 | 46577472 |
| Injury corneal | 17.76 | 12.26 | 5 | 36590 | 63 | 46649404 |
| Hypoaesthesia | 17.75 | 12.26 | 42 | 36553 | 118827 | 46530640 |
| Induced abortion failed | 17.70 | 12.26 | 7 | 36588 | 263 | 46649204 |
| Alcoholic | 17.62 | 12.26 | 5 | 36590 | 65 | 46649402 |
| Cystitis noninfective | 17.61 | 12.26 | 10 | 36585 | 853 | 46648614 |
| Therapeutic product effect decreased | 17.61 | 12.26 | 118 | 36477 | 82483 | 46566984 |
| Application site vesicles | 17.32 | 12.26 | 12 | 36583 | 1452 | 46648015 |
| Influenza | 17.29 | 12.26 | 27 | 36568 | 89243 | 46560224 |
| Hypersensitivity | 17.27 | 12.26 | 187 | 36408 | 150134 | 46499333 |
| Influenza like illness | 17.25 | 12.26 | 12 | 36583 | 57558 | 46591909 |
| Blood pressure increased | 17.18 | 12.26 | 47 | 36548 | 126619 | 46522848 |
| Injection site reaction | 17.16 | 12.26 | 8 | 36587 | 47841 | 46601626 |
| Accidental death | 17.06 | 12.26 | 13 | 36582 | 1822 | 46647645 |
| Confusional state | 17.04 | 12.26 | 196 | 36399 | 159696 | 46489771 |
| Cardiac ventricular thrombosis | 16.98 | 12.26 | 8 | 36587 | 463 | 46649004 |
| Congenital umbilical hernia | 16.86 | 12.26 | 8 | 36587 | 470 | 46648997 |
| Multiple sclerosis relapse | 16.80 | 12.26 | 6 | 36589 | 42119 | 46607348 |
| Fibromyalgia | 16.72 | 12.26 | 4 | 36591 | 36459 | 46613008 |
| Back pain | 16.72 | 12.26 | 244 | 36351 | 209795 | 46439672 |
| Accidental exposure to product | 16.62 | 12.26 | 45 | 36550 | 21036 | 46628431 |
| Diverticulitis | 16.44 | 12.26 | 3 | 36592 | 33036 | 46616431 |
| Lip injury | 16.43 | 12.26 | 9 | 36586 | 716 | 46648751 |
| Application site necrosis | 16.38 | 12.26 | 3 | 36592 | 3 | 46649464 |
| Extradural abscess | 16.34 | 12.26 | 9 | 36586 | 724 | 46648743 |
| Rhinovirus infection | 16.21 | 12.26 | 17 | 36578 | 3619 | 46645848 |
| Therapeutic product effect incomplete | 15.75 | 12.26 | 23 | 36572 | 78130 | 46571337 |
| Asphyxia | 15.51 | 12.26 | 20 | 36575 | 5306 | 46644161 |
| Pain in extremity | 15.50 | 12.26 | 129 | 36466 | 258551 | 46390916 |
| Urinary tract infection | 15.50 | 12.26 | 105 | 36490 | 220161 | 46429306 |
| Treatment failure | 15.45 | 12.26 | 31 | 36564 | 93056 | 46556411 |
| Constipation | 15.45 | 12.26 | 77 | 36518 | 174020 | 46475447 |
| Gastrointestinal haemorrhage | 15.37 | 12.26 | 23 | 36572 | 77350 | 46572117 |
| Recalled product administered | 15.01 | 12.26 | 6 | 36589 | 232 | 46649235 |
| Circulatory collapse | 14.93 | 12.26 | 44 | 36551 | 21580 | 46627887 |
| Transmission of an infectious agent via product | 14.88 | 12.26 | 5 | 36590 | 117 | 46649350 |
| Psoriatic arthropathy | 14.82 | 12.26 | 5 | 36590 | 36374 | 46613093 |
| Neutropenic sepsis | 14.81 | 12.26 | 31 | 36564 | 12293 | 46637174 |
| Parathyroid hyperplasia | 14.68 | 12.26 | 5 | 36590 | 122 | 46649345 |
| Hypertension | 14.62 | 12.26 | 92 | 36503 | 196264 | 46453203 |
| Dyspnoea | 14.59 | 12.26 | 301 | 36294 | 515247 | 46134220 |
| Electrocardiogram QT prolonged | 14.56 | 12.26 | 79 | 36516 | 51246 | 46598221 |
| Oedema peripheral | 14.54 | 12.26 | 70 | 36525 | 159636 | 46489831 |
| Platelet count decreased | 14.41 | 12.26 | 36 | 36559 | 99988 | 46549479 |
| Pancytopenia | 14.40 | 12.26 | 28 | 36567 | 85030 | 46564437 |
| Musculoskeletal stiffness | 14.33 | 12.26 | 35 | 36560 | 97958 | 46551509 |
| Myalgia | 14.31 | 12.26 | 49 | 36546 | 123039 | 46526428 |
| Breast cancer | 14.29 | 12.26 | 9 | 36586 | 45509 | 46603958 |
| Arthralgia | 14.15 | 12.26 | 201 | 36394 | 364402 | 46285065 |
| Catheter site pruritus | 14.10 | 12.26 | 12 | 36583 | 1967 | 46647500 |
| Catheter site vesicles | 14.09 | 12.26 | 6 | 36589 | 273 | 46649194 |
| Pulmonary oedema | 14.06 | 12.26 | 78 | 36517 | 51027 | 46598440 |
| Toxicologic test abnormal | 14.00 | 12.26 | 8 | 36587 | 691 | 46648776 |
| Abdominal discomfort | 13.91 | 12.26 | 66 | 36529 | 151099 | 46498368 |
| Infection | 13.89 | 12.26 | 163 | 36432 | 133429 | 46516038 |
| Purulent discharge | 13.85 | 12.26 | 18 | 36577 | 4812 | 46644655 |
| Oropharyngeal pain | 13.83 | 12.26 | 23 | 36572 | 74145 | 46575322 |
| Genital rash | 13.79 | 12.26 | 7 | 36588 | 477 | 46648990 |
| Polymenorrhagia | 13.69 | 12.26 | 4 | 36591 | 58 | 46649409 |
| Thrombocytopenia | 13.65 | 12.26 | 52 | 36543 | 126529 | 46522938 |
| Parvimonas micra infection | 13.64 | 12.26 | 3 | 36592 | 12 | 46649455 |
| Application site reaction | 13.58 | 12.26 | 8 | 36587 | 731 | 46648736 |
| Neck pain | 13.54 | 12.26 | 14 | 36581 | 55292 | 46594175 |
| No adverse event | 13.44 | 12.26 | 5 | 36590 | 34226 | 46615241 |
| Productive cough | 13.39 | 12.26 | 12 | 36583 | 50703 | 46598764 |
| Wrong technique in product usage process | 13.07 | 12.26 | 14 | 36581 | 54408 | 46595059 |
| Mobility decreased | 13.04 | 12.26 | 17 | 36578 | 60577 | 46588890 |
| Derealisation | 12.97 | 12.26 | 8 | 36587 | 795 | 46648672 |
| White blood cell count decreased | 12.83 | 12.26 | 45 | 36550 | 112186 | 46537281 |
| Shock | 12.82 | 12.26 | 42 | 36553 | 21803 | 46627664 |
| Blood pressure fluctuation | 12.73 | 12.26 | 4 | 36591 | 30444 | 46619023 |
| Hyponatraemia | 12.71 | 12.26 | 39 | 36556 | 101293 | 46548174 |
| Syncope | 12.68 | 12.26 | 41 | 36554 | 104762 | 46544705 |
| Aspiration | 12.67 | 12.26 | 25 | 36570 | 9506 | 46639961 |
| Alcohol withdrawal syndrome | 12.66 | 12.26 | 8 | 36587 | 829 | 46648638 |
| Chronic obstructive pulmonary disease | 12.58 | 12.26 | 16 | 36579 | 57617 | 46591850 |
| Cardiac death | 12.56 | 12.26 | 7 | 36588 | 576 | 46648891 |
| Metastases to bone | 12.49 | 12.26 | 36 | 36559 | 17440 | 46632027 |
| Blood cholesterol increased | 12.44 | 12.26 | 8 | 36587 | 40005 | 46609462 |
| Hyperlipasaemia | 12.33 | 12.26 | 7 | 36588 | 597 | 46648870 |
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Drug abuse | 2346.58 | 13.00 | 1239 | 25892 | 80833 | 29844514 |
| Completed suicide | 2314.46 | 13.00 | 1310 | 25821 | 98182 | 29827165 |
| Toxicity to various agents | 2131.84 | 13.00 | 1537 | 25594 | 175646 | 29749701 |
| Intentional overdose | 595.61 | 13.00 | 404 | 26727 | 41077 | 29884270 |
| Cardio-respiratory arrest | 489.55 | 13.00 | 409 | 26722 | 56897 | 29868450 |
| Alcohol abuse | 472.36 | 13.00 | 179 | 26952 | 5174 | 29920173 |
| Overdose | 418.09 | 13.00 | 445 | 26686 | 83892 | 29841455 |
| Suicide attempt | 392.36 | 13.00 | 299 | 26832 | 36398 | 29888949 |
| Alcohol interaction | 363.66 | 13.00 | 124 | 27007 | 2618 | 29922729 |
| Intentional product misuse | 339.07 | 13.00 | 268 | 26863 | 34399 | 29890948 |
| Alcohol poisoning | 214.72 | 13.00 | 92 | 27039 | 3672 | 29921675 |
| Suspected suicide | 213.01 | 13.00 | 87 | 27044 | 3074 | 29922273 |
| Substance abuse | 201.32 | 13.00 | 107 | 27024 | 6933 | 29918414 |
| Drug dependence | 151.13 | 13.00 | 137 | 26994 | 21158 | 29904189 |
| Alcohol use | 148.22 | 13.00 | 71 | 27060 | 3684 | 29921663 |
| Anaphylactic reaction | 130.02 | 13.00 | 143 | 26988 | 27839 | 29897508 |
| Drug ineffective | 126.90 | 13.00 | 76 | 27055 | 340311 | 29585036 |
| Recalled product administered | 111.15 | 13.00 | 32 | 27099 | 376 | 29924971 |
| Burkholderia test positive | 107.42 | 13.00 | 32 | 27099 | 427 | 29924920 |
| Respiratory arrest | 103.44 | 13.00 | 130 | 27001 | 29128 | 29896219 |
| Poisoning deliberate | 95.33 | 13.00 | 62 | 27069 | 5842 | 29919505 |
| Asphyxia | 95.11 | 13.00 | 60 | 27071 | 5365 | 29919982 |
| Incorrect route of product administration | 92.67 | 13.00 | 79 | 27052 | 11236 | 29914111 |
| Burkholderia infection | 91.86 | 13.00 | 21 | 27110 | 87 | 29925260 |
| Aggression | 89.87 | 13.00 | 137 | 26994 | 36770 | 29888577 |
| Coma | 88.58 | 13.00 | 143 | 26988 | 40306 | 29885041 |
| Blood alcohol increased | 85.22 | 13.00 | 32 | 27099 | 899 | 29924448 |
| Cardiac arrest | 82.87 | 13.00 | 227 | 26904 | 92623 | 29832724 |
| Respiratory depression | 77.67 | 13.00 | 72 | 27059 | 11431 | 29913916 |
| Product contamination microbial | 76.41 | 13.00 | 27 | 27104 | 635 | 29924712 |
| Intentional product use issue | 71.96 | 13.00 | 123 | 27008 | 36317 | 29889030 |
| Recalled product | 58.01 | 13.00 | 19 | 27112 | 352 | 29924995 |
| Alcohol withdrawal syndrome | 55.87 | 13.00 | 28 | 27103 | 1603 | 29923744 |
| Intentional self-injury | 55.75 | 13.00 | 65 | 27066 | 13467 | 29911880 |
| Poisoning | 52.54 | 13.00 | 58 | 27073 | 11324 | 29914023 |
| Drug withdrawal syndrome | 51.71 | 13.00 | 76 | 27055 | 19733 | 29905614 |
| Fatigue | 51.71 | 13.00 | 136 | 26995 | 320537 | 29604810 |
| Suicidal ideation | 50.26 | 13.00 | 105 | 27026 | 36009 | 29889338 |
| Burkholderia cepacia complex infection | 48.51 | 13.00 | 14 | 27117 | 166 | 29925181 |
| Diarrhoea | 45.69 | 13.00 | 153 | 26978 | 333950 | 29591397 |
| Chemical burn of skin | 45.07 | 13.00 | 10 | 27121 | 35 | 29925312 |
| Accidental death | 41.54 | 13.00 | 25 | 27106 | 2054 | 29923293 |
| Off label use | 41.45 | 13.00 | 104 | 27027 | 249186 | 29676161 |
| Sopor | 39.07 | 13.00 | 49 | 27082 | 10942 | 29914405 |
| Road traffic accident | 38.22 | 13.00 | 61 | 27070 | 17010 | 29908337 |
| Ex-drug abuser | 37.70 | 13.00 | 12 | 27119 | 202 | 29925145 |
| Myocardial infarction | 37.64 | 13.00 | 35 | 27096 | 125590 | 29799757 |
| Interstitial lung disease | 37.63 | 13.00 | 5 | 27126 | 60192 | 29865155 |
| Alcoholism | 36.80 | 13.00 | 28 | 27103 | 3386 | 29921961 |
| Drug screen positive | 36.55 | 13.00 | 31 | 27100 | 4376 | 29920971 |
| Alcohol intolerance | 36.23 | 13.00 | 14 | 27117 | 426 | 29924921 |
| Pneumonia | 36.18 | 13.00 | 168 | 26963 | 334138 | 29591209 |
| Sputum culture positive | 35.50 | 13.00 | 22 | 27109 | 1905 | 29923442 |
| Amnesia | 35.34 | 13.00 | 72 | 27059 | 24249 | 29901098 |
| Anaemia | 35.15 | 13.00 | 86 | 27045 | 207906 | 29717441 |
| Chemical burn | 34.25 | 13.00 | 11 | 27120 | 191 | 29925156 |
| Tachycardia | 32.00 | 13.00 | 142 | 26989 | 73597 | 29851750 |
| Acanthamoeba keratitis | 31.80 | 13.00 | 9 | 27122 | 99 | 29925248 |
| Medication error | 31.56 | 13.00 | 63 | 27068 | 20909 | 29904438 |
| Nausea | 31.06 | 13.00 | 151 | 26980 | 296806 | 29628541 |
| General physical health deterioration | 30.94 | 13.00 | 27 | 27104 | 99917 | 29825430 |
| Disease progression | 30.79 | 13.00 | 17 | 27114 | 79857 | 29845490 |
| Allergy to chemicals | 30.65 | 13.00 | 8 | 27123 | 63 | 29925284 |
| Cough | 30.04 | 13.00 | 42 | 27089 | 125600 | 29799747 |
| Arthralgia | 29.94 | 13.00 | 48 | 27083 | 135743 | 29789604 |
| Hepatic fibrosis | 29.31 | 13.00 | 25 | 27106 | 3555 | 29921792 |
| Product dose omission issue | 29.29 | 13.00 | 24 | 27107 | 91607 | 29833740 |
| Exposure to toxic agent | 29.08 | 13.00 | 16 | 27115 | 1109 | 29924238 |
| Asthenia | 29.04 | 13.00 | 103 | 27028 | 221187 | 29704160 |
| Application site vesicles | 28.96 | 13.00 | 13 | 27118 | 580 | 29924767 |
| Malignant neoplasm progression | 28.42 | 13.00 | 15 | 27116 | 72272 | 29853075 |
| Suspected transmission of an infectious agent via product | 28.35 | 13.00 | 12 | 27119 | 464 | 29924883 |
| Physical assault | 27.96 | 13.00 | 16 | 27115 | 1197 | 29924150 |
| Application site rash | 27.71 | 13.00 | 14 | 27117 | 815 | 29924532 |
| Homicide | 27.38 | 13.00 | 15 | 27116 | 1031 | 29924316 |
| Drug abuser | 26.75 | 13.00 | 26 | 27105 | 4375 | 29920972 |
| Miosis | 26.58 | 13.00 | 34 | 27097 | 7742 | 29917605 |
| Dyspnoea | 26.55 | 13.00 | 185 | 26946 | 333110 | 29592237 |
| Decreased appetite | 26.08 | 13.00 | 61 | 27070 | 149849 | 29775498 |
| Foetal alcohol syndrome | 25.90 | 13.00 | 9 | 27122 | 201 | 29925146 |
| Osteonecrosis of jaw | 25.73 | 13.00 | 54 | 27077 | 18564 | 29906783 |
| Dermatitis contact | 25.31 | 13.00 | 22 | 27109 | 3209 | 29922138 |
| Condition aggravated | 24.87 | 13.00 | 55 | 27076 | 137811 | 29787536 |
| White blood cell count decreased | 24.41 | 13.00 | 24 | 27107 | 83923 | 29841424 |
| Sensitisation | 23.71 | 13.00 | 8 | 27123 | 163 | 29925184 |
| Cardiac failure congestive | 23.56 | 13.00 | 25 | 27106 | 84382 | 29840965 |
| Weight increased | 23.47 | 13.00 | 20 | 27111 | 74893 | 29850454 |
| Accident | 23.20 | 13.00 | 22 | 27109 | 3591 | 29921756 |
| Dysarthria | 22.75 | 13.00 | 70 | 27061 | 30420 | 29894927 |
| Culture positive | 22.50 | 13.00 | 12 | 27119 | 782 | 29924565 |
| Depressed level of consciousness | 21.66 | 13.00 | 80 | 27051 | 38142 | 29887205 |
| Impaired driving ability | 21.47 | 13.00 | 18 | 27113 | 2500 | 29922847 |
| Weight decreased | 21.31 | 13.00 | 68 | 27063 | 150853 | 29774494 |
| Drug use disorder | 21.28 | 13.00 | 20 | 27111 | 3228 | 29922119 |
| Somnolence | 21.10 | 13.00 | 155 | 26976 | 96608 | 29828739 |
| Oedema peripheral | 20.96 | 13.00 | 40 | 27091 | 105792 | 29819555 |
| Pain in extremity | 20.68 | 13.00 | 43 | 27088 | 110178 | 29815169 |
| Agitation | 20.41 | 13.00 | 100 | 27031 | 53973 | 29871374 |
| Gun shot wound | 20.37 | 13.00 | 13 | 27118 | 1185 | 29924162 |
| Musculoskeletal stiffness | 20.14 | 13.00 | 4 | 27127 | 35877 | 29889470 |
| Back pain | 20.12 | 13.00 | 39 | 27092 | 102557 | 29822790 |
| Capillary nail refill test abnormal | 19.80 | 13.00 | 5 | 27126 | 34 | 29925313 |
| Dextrocardia | 19.60 | 13.00 | 7 | 27124 | 170 | 29925177 |
| Paranoia | 19.58 | 13.00 | 34 | 27097 | 10154 | 29915193 |
| Peripheral swelling | 19.50 | 13.00 | 16 | 27115 | 61058 | 29864289 |
| Shock | 19.46 | 13.00 | 55 | 27076 | 22804 | 29902543 |
| Dehydration | 19.36 | 13.00 | 53 | 27078 | 123486 | 29801861 |
| Catheter site rash | 18.59 | 13.00 | 7 | 27124 | 198 | 29925149 |
| Hepatic haematoma | 18.57 | 13.00 | 9 | 27122 | 479 | 29924868 |
| Therapeutic product effect incomplete | 18.52 | 13.00 | 4 | 27127 | 33830 | 29891517 |
| Drug intolerance | 18.39 | 13.00 | 9 | 27122 | 45282 | 29880065 |
| Asthma | 18.38 | 13.00 | 5 | 27126 | 36169 | 29889178 |
| Product use in unapproved indication | 18.24 | 13.00 | 24 | 27107 | 73669 | 29851678 |
| Joint swelling | 18.07 | 13.00 | 10 | 27121 | 46936 | 29878411 |
| Cerebrovascular accident | 17.92 | 13.00 | 30 | 27101 | 83447 | 29841900 |
| Cardiac failure | 17.89 | 13.00 | 30 | 27101 | 83388 | 29841959 |
| Renal failure | 17.58 | 13.00 | 59 | 27072 | 128907 | 29796440 |
| Catheter site discharge | 17.48 | 13.00 | 9 | 27122 | 545 | 29924802 |
| Myalgia | 16.97 | 13.00 | 27 | 27104 | 76640 | 29848707 |
| Pulseless electrical activity | 16.52 | 13.00 | 24 | 27107 | 6163 | 29919184 |
| Haemoglobin decreased | 16.38 | 13.00 | 51 | 27080 | 114047 | 29811300 |
| Pulmonary oedema | 16.36 | 13.00 | 81 | 27050 | 43894 | 29881453 |
| Product contamination | 16.15 | 13.00 | 9 | 27122 | 640 | 29924707 |
| Metabolic acidosis | 16.13 | 13.00 | 72 | 27059 | 37389 | 29887958 |
| Alcoholic liver disease | 16.02 | 13.00 | 9 | 27122 | 650 | 29924697 |
| Product package associated injury | 15.95 | 13.00 | 3 | 27128 | 3 | 29925344 |
| Somnambulism | 15.91 | 13.00 | 17 | 27114 | 3197 | 29922150 |
| Nasopharyngitis | 15.79 | 13.00 | 18 | 27113 | 58831 | 29866516 |
| Pyrexia | 15.69 | 13.00 | 181 | 26950 | 294308 | 29631039 |
| Unresponsive to stimuli | 15.56 | 13.00 | 56 | 27075 | 26363 | 29898984 |
| Hypotension | 15.35 | 13.00 | 261 | 26870 | 200304 | 29725043 |
| Application site irritation | 15.31 | 13.00 | 9 | 27122 | 708 | 29924639 |
| Blood glucose increased | 15.26 | 13.00 | 20 | 27111 | 61510 | 29863837 |
| Mydriasis | 15.21 | 13.00 | 23 | 27108 | 6120 | 29919227 |
| Abnormal behaviour | 14.83 | 13.00 | 54 | 27077 | 25569 | 29899778 |
| Loss of consciousness | 14.46 | 13.00 | 122 | 27009 | 79253 | 29846094 |
| Bladder discomfort | 14.42 | 13.00 | 5 | 27126 | 111 | 29925236 |
| Catheter site irritation | 14.42 | 13.00 | 5 | 27126 | 111 | 29925236 |
| Suicidal behaviour | 14.30 | 13.00 | 11 | 27120 | 1351 | 29923996 |
| Cluster headache | 14.29 | 13.00 | 8 | 27123 | 574 | 29924773 |
| Pulmonary embolism | 14.21 | 13.00 | 31 | 27100 | 78104 | 29847243 |
| Platelet count decreased | 14.15 | 13.00 | 49 | 27082 | 106080 | 29819267 |
| Product preparation error | 14.14 | 13.00 | 12 | 27119 | 1694 | 29923653 |
| Dizziness | 14.12 | 13.00 | 111 | 27020 | 194798 | 29730549 |
| Chemical poisoning | 14.01 | 13.00 | 5 | 27126 | 121 | 29925226 |
| Toxicologic test abnormal | 13.90 | 13.00 | 8 | 27123 | 605 | 29924742 |
| Death | 13.81 | 13.00 | 422 | 26709 | 356861 | 29568486 |
| Infusion related reaction | 13.74 | 13.00 | 10 | 27121 | 40554 | 29884793 |
| Skin abrasion | 13.70 | 13.00 | 22 | 27109 | 6164 | 29919183 |
| Pneumonitis | 13.57 | 13.00 | 4 | 27127 | 27450 | 29897897 |
| Disturbance in social behaviour | 13.55 | 13.00 | 11 | 27120 | 1460 | 29923887 |
| Anion gap | 13.51 | 13.00 | 8 | 27123 | 638 | 29924709 |
| Application site reaction | 13.40 | 13.00 | 7 | 27124 | 437 | 29924910 |
| Drug diversion | 13.29 | 13.00 | 9 | 27122 | 907 | 29924440 |
| Renal impairment | 13.26 | 13.00 | 36 | 27095 | 84148 | 29841199 |
| Non-cardiogenic pulmonary oedema | 13.03 | 13.00 | 8 | 27123 | 681 | 29924666 |
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A01AB03 | ALIMENTARY TRACT AND METABOLISM STOMATOLOGICAL PREPARATIONS STOMATOLOGICAL PREPARATIONS Antiinfectives and antiseptics for local oral treatment |
| ATC | B05CA02 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS IRRIGATING SOLUTIONS Antiinfectives |
| ATC | D08AC02 | DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Biguanides and amidines |
| ATC | D09AA12 | DERMATOLOGICALS MEDICATED DRESSINGS MEDICATED DRESSINGS Medicated dressings with antiinfectives |
| ATC | R02AA05 | RESPIRATORY SYSTEM THROAT PREPARATIONS THROAT PREPARATIONS Antiseptics |
| ATC | S01AX09 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFECTIVES Other antiinfectives |
| ATC | S02AA09 | SENSORY ORGANS OTOLOGICALS ANTIINFECTIVES Antiinfectives |
| ATC | S03AA04 | SENSORY ORGANS OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS ANTIINFECTIVES Antiinfectives |
| ATC | D08AC52 | DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Biguanides and amidines |
| FDA PE | N0000008478 | Decreased Cell Wall Integrity |
| CHEBI has role | CHEBI:33282 | antibacterials |
| CHEBI has role | CHEBI:35441 | anti-infective drugs |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000891 | Anti-Infective Agents, Local |
| MeSH PA | D003879 | Dermatologic Agents |
| MeSH PA | D003358 | Cosmetics |
| MeSH PA | D004202 | Disinfectants |
| MeSH PA | D009067 | Mouthwashes |
Drug Use (View source of the data)
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Gingivitis | indication | 66383009 | DOID:3087 |
| Mouth Infection Prevention | indication | ||
| Denture stomatitis | off-label use | 69254008 | DOID:11875 |
| Aphthous ulcer of mouth | off-label use | 426965005 | DOID:9663 |
| Dental Plaque Prevention | off-label use | ||
| Periodontitis | contraindication | 41565005 | DOID:824 |
| Open wound | contraindication | 125643001 | |
| Front Tooth Fillings | contraindication |
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 11.17 | Basic |
| pKa2 | 10.57 | Basic |
| pKa3 | 3.32 | Basic |
| pKa4 | 2.72 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
| Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
|---|---|---|---|---|---|---|---|---|---|
| 3.15%;70% (1.6ML) | PREVANTICS SWABSTICK | PROF DSPLS | N021524 | June 3, 2005 | OTC | SWAB | TOPICAL | Feb. 14, 2021 | DRUG FACTS LABELING CHANGES UNDER THE DIRECTIONS HEADING TO REVISE THE STATED PREPARATION TIME OF A DRY SITE FROM 120 SECONDS SCRUBBING AND 90 SECONDS DRYING TO 30 SECONDS SCRUBBING AND 30 SECONDS DRYING |
| 3.15%;70% (1ML) | PREVANTICS SWAB | PROF DSPLS | N021524 | June 3, 2005 | OTC | SWAB | TOPICAL | Feb. 14, 2021 | DRUG FACTS LABELING CHANGES UNDER THE DIRECTIONS HEADING TO REVISE THE STATED PREPARATION TIME OF A DRY SITE FROM 120 SECONDS SCRUBBING AND 90 SECONDS DRYING TO 30 SECONDS SCRUBBING AND 30 SECONDS DRYING |
| 3.15%;70% (5.1ML) | PREVANTICS MAXI SWABSTICK | PROF DSPLS | N021524 | June 3, 2005 | OTC | SWAB | TOPICAL | Feb. 14, 2021 | DRUG FACTS LABELING CHANGES UNDER THE DIRECTIONS HEADING TO REVISE THE STATED PREPARATION TIME OF A DRY SITE FROM 120 SECONDS SCRUBBING AND 90 SECONDS DRYING TO 30 SECONDS SCRUBBING AND 30 SECONDS DRYING |
| 2%;70% | SOLUPREP | 3M HEALTH CARE | N208288 | Aug. 8, 2018 | OTC | SOLUTION | TOPICAL | Aug. 8, 2021 | NEW PRODUCT |
| 2% | READYPREP CHG | MEDLINE INDUSTRIES | N207964 | Nov. 20, 2018 | OTC | CLOTH | TOPICAL | Nov. 20, 2021 | NEW PRODUCT |
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Solute carrier family 22 member 3 | Transporter | IC50 | 6.39 | CHEMBL | |||||
| Solute carrier family 22 member 1 | Transporter | IC50 | 6.68 | CHEMBL | |||||
| Solute carrier family 22 member 2 | Transporter | IC50 | 6.40 | CHEMBL | |||||
| Matrix metalloproteinase-9 | Enzyme | IC50 | 5.12 | CHEMBL | |||||
| Multidrug and toxin extrusion protein 2 | Transporter | IC50 | 6.30 | CHEMBL | |||||
| Multidrug and toxin extrusion protein 1 | Transporter | IC50 | 6.15 | CHEMBL | |||||
| 72 kDa type IV collagenase | Enzyme | IC50 | 5.12 | CHEMBL | |||||
| Trypanothione reductase | Enzyme | Ki | 5.70 | CHEMBL | |||||
| CAAX prenyl protease 2 | Unclassified | AC50 | 5.24 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D00858 | KEGG_DRUG |
| 18472-51-0 | SECONDARY_CAS_RN |
| 4019393 | VANDF |
| 4019673 | VANDF |
| C0008196 | UMLSCUI |
| CHEBI:3614 | CHEBI |
| CHEMBL790 | ChEMBL_ID |
| CHEMBL1628 | ChEMBL_ID |
| CHEMBL4297088 | ChEMBL_ID |
| CHEMBL1484251 | ChEMBL_ID |
| DB00878 | DRUGBANK_ID |
| D002710 | MESH_DESCRIPTOR_UI |
| C010882 | MESH_SUPPLEMENTAL_RECORD_UI |
| 9552079 | PUBCHEM_CID |
| 500 | INN_ID |
| R4KO0DY52L | UNII |
| 20791 | RXNORM |
| 4411 | MMSL |
| 6085 | MMSL |
| 003177 | NDDF |
| 003674 | NDDF |
| 003723 | NDDF |
| 108895000 | SNOMEDCT_US |
| 373568007 | SNOMEDCT_US |
| 767425002 | SNOMEDCT_US |
| 96316004 | SNOMEDCT_US |
| 96318003 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Chlorhexidine Gluconate 0.12% Oral Rinse | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0003 | LIQUID | 1.20 [iU] | BUCCAL | ANDA | 18 sections |
| Chlorhexidine Gluconate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0101 | LIQUID | 0.12 mg | ORAL | ANDA | 17 sections |
| Cardinal Health Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0113 | SOLUTION | 2 g | TOPICAL | NDA | 14 sections |
| Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0115 | LIQUID | 4 mg | TOPICAL | NDA | 14 sections |
| Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0137 | LIQUID | 4 mg | TOPICAL | NDA | 14 sections |
| Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0161 | LIQUID | 4 mg | TOPICAL | NDA | 14 sections |
| Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0162 | LIQUID | 4 mg | TOPICAL | NDA | 14 sections |
| Chlorhexidine Gluconate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0175 | RINSE | 1.20 mg | ORAL | ANDA | 17 sections |
| BETASEPT | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0200 | SOLUTION | 0.04 mg | TOPICAL | NDA | 14 sections |
| Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0228 | LIQUID | 4 mg | TOPICAL | NDA | 15 sections |
| Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0237 | LIQUID | 4 mg | TOPICAL | NDA | 14 sections |
| Denti-Care Denti-RinseChlorhexidine Gluconate Oral Rinse | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0244 | LIQUID | 1.20 mg | DENTAL | ANDA | 13 sections |
| Chlorhexidine Gluconate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0301 | RINSE | 1.20 mg | ORAL | ANDA | 19 sections |
| Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0401 | LIQUID | 4 mg | TOPICAL | NDA | 14 sections |
| ANTISEPTIC SKIN CLEANSER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0407 | SOLUTION | 4 g | TOPICAL | NDA | 15 sections |
| BD E-Z Scrub | HUMAN OTC DRUG LABEL | 1 | 0116-0505 | SOLUTION | 40 g | TOPICAL | NDA | 14 sections |
| BD E-Z Scrub | HUMAN OTC DRUG LABEL | 1 | 0116-0506 | SOLUTION | 20 mg | TOPICAL | NDA | 14 sections |
| Peridex | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0620 | RINSE | 1.20 mg | ORAL | NDA | 21 sections |
| Scrub CareExidine-2 CHG | HUMAN OTC DRUG LABEL | 1 | 0116-0722 | SOLUTION | 2 mg | TOPICAL | NDA | 14 sections |
| Antiseptic Skin Cleanser | HUMAN OTC DRUG LABEL | 1 | 0116-0767 | LIQUID | 4 g | TOPICAL | NDA | 13 sections |
| NUPRO Chlorhexidine Gluconate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0116-0800 | RINSE | 1.20 mg | ORAL | ANDA | 20 sections |
| DYNULL-HEX2 | HUMAN OTC DRUG LABEL | 1 | 0116-1021 | LIQUID | 2 g | TOPICAL | NDA | 13 sections |
| DYNULL-HEX2 | HUMAN OTC DRUG LABEL | 1 | 0116-1021 | LIQUID | 2 g | TOPICAL | NDA | 13 sections |
| Dyna-Hex 2 | HUMAN OTC DRUG LABEL | 1 | 0116-1022 | SOLUTION | 20 mg | TOPICAL | NDA | 14 sections |
| DYNULL-HEX 4 | HUMAN OTC DRUG LABEL | 1 | 0116-1060 | LIQUID | 4 g | TOPICAL | NDA | 14 sections |
| ANTISEPTIC SKIN CLEANSER | HUMAN OTC DRUG LABEL | 1 | 0116-1061 | SOLUTION | 4 g | TOPICAL | NDA | 13 sections |
| ANTISEPTIC SKIN CLEANSER | HUMAN OTC DRUG LABEL | 1 | 0116-1061 | SOLUTION | 4 g | TOPICAL | NDA | 13 sections |
| ANTISEPTIC SKIN CLEANSER | HUMAN OTC DRUG LABEL | 1 | 0116-1061 | SOLUTION | 4 g | TOPICAL | NDA | 13 sections |
| Bactoshield CHG | HUMAN OTC DRUG LABEL | 1 | 0116-1322 | SOLUTION | 20 mg | TOPICAL | NDA | 16 sections |
| Bactoshield CHG | HUMAN OTC DRUG LABEL | 1 | 0116-1344 | SOLUTION | 40 mg | TOPICAL | NDA | 15 sections |