cefaloglycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, cefalosporanic acid derivatives 572 3577-01-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cephaloglycin
  • cefaloglycin
  • cefaloglycine
  • cephaloglycine
  • kefglycin
  • kafocin
A cephalorsporin antibiotic.
  • Molecular weight: 405.43
  • Formula: C18H19N3O6S
  • CLOGP: -2.56
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 3
  • TPSA: 139.03
  • ALOGS: -3.44
  • ROTB: 7

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
June 12, 1970 FDA LILLY

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
CHEBI has role CHEBI:33281 antibiotics

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.39 acidic
pKa2 13.53 acidic
pKa3 7.67 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Bacterial penicillin-binding protein Enzyme INHIBITOR CHEMBL CHEMBL

External reference:

IDSource
D01949 KEGG_DRUG
22202-75-1 SECONDARY_CAS_RN
CHEBI:34613 CHEBI
CHEMBL1200971 ChEMBL_ID
12193 IUPHAR_LIGAND_ID
DB00689 DRUGBANK_ID
002714 NDDF
39123009 SNOMEDCT_US
C0007721 UMLSCUI
D002507 MESH_DESCRIPTOR_UI
19150 PUBCHEM_CID
NE7R11LA95 UNII

Pharmaceutical products:

None