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| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5707 | 2098615-91-7 |
| Molecule | Description |
|---|---|
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Synonyms:
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Eladocagene exuparvovec is a gene therapy medicinal product that expresses the human aromatic L-amino acid decarboxylase enzyme (hAADC). It is a non-replicating recombinant adeno-associated virus serotype 2 (AAV2) based vector containing the cDNA of the human dopa decarboxylase (DDC) gene under the control of the cytomegalovirus immediate-early promoter.
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| Date | Agency | Company | Orphan |
|---|---|---|---|
| Aug. 17, 2022 | EMA | PTC Therapeutics International Limited |
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| Source | Code | Description |
|---|---|---|
| ATC | A16AB26 | ALIMENTARY TRACT AND METABOLISM OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS Enzymes |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Deficiency of aromatic-L-amino-acid decarboxylase | indication | 124600004 | DOID:0090123 |
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| ID | Source |
|---|---|
| CHEBI:757596 | CHEBI |
| CHEMBL4298189 | ChEMBL_ID |
| C000731825 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB16780 | DRUGBANK_ID |
| 41245311000001107 | SNOMEDCT_US |
| 4043630 | VANDF |
| C5419302 | UMLSCUI |
| 10885 | INN_ID |
| D12407 | KEGG_DRUG |
| S51J6N56M7 | UNII |
| 2698762 | RXNORM |
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| KEBILIDI | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52856-601 | SUSPENSION | 560000000000 {GC} | INTRACEREBRAL | BLA | 24 sections |