norgestomet 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| steroids, progestogens | 5588 | 25092-41-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Synthetic 19-norprogesterone that synchronizes estrus in cattle without reducing fertility. It affects pituitary gonadotropins the menstrual cycle in humans
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cattle | Synchronization of estrus/ovulation | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Syncro-Mate-B | Boehringer lngelheim Animal Health USA Inc. | 2 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Progesterone receptor | Nuclear hormone receptor | EC50 | 8.35 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| CHEMBL2104744 | ChEMBL_ID |
| C100284 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB11440 | DRUGBANK_ID |
| C0068993 | UMLSCUI |
| 3663 | INN_ID |
| 421962009 | SNOMEDCT_US |
| 96358001 | SNOMEDCT_US |
| D05210 | KEGG_DRUG |
| 9820838 | PUBCHEM_CID |
| 3L33UD42X4 | UNII |
Pharmaceutical products:
None