monensin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5580 | 17090-79-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts development of acquired immunity to the majority of coccidial species. Monensin is sodium and proton selective ionophore and is widely used as such in biochemical studies
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000935 | Antifungal Agents |
| MeSH PA | D000977 | Antiparasitic Agents |
| MeSH PA | D000981 | Antiprotozoal Agents |
| MeSH PA | D003049 | Coccidiostats |
| MeSH PA | D004791 | Enzyme Inhibitors |
| MeSH PA | D007476 | Ionophores |
| MeSH PA | D049990 | Membrane Transport Modulators |
| MeSH PA | D061209 | Proton Ionophores |
| MeSH PA | D061210 | Sodium Ionophores |
| MeSH PA | D014475 | Uncoupling Agents |
| CHEBI has role | CHEBI:24869 | ionophores |
| CHEBI has role | CHEBI:35718 | antifungal agents |
| CHEBI has role | CHEBI:35818 | coccidiostats |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Chickens | Prevention of coccidiosis caused by Eimeria necatrix | Indication |
| Chickens | Prevention of coccidiosis caused by Eimeria tenella | Indication |
| Chickens | Prevention of coccidiosis caused by E acervulina | Indication |
| Chickens | Prevention of coccidiosis caused by E brunetti | Indication |
| Chickens | Prevention of coccidiosis caused by E mivati | Indication |
| Chickens | Prevention of coccidiosis caused by E maxima | Indication |
| Turkeys | Prevention of coccidiosis caused by Eimeria adenoeides | Indication |
| Turkeys | Prevention of coccidiosis caused by Emeleagrimitis | Indication |
| Turkeys | Prevention of coccidiosis caused by E gallopavonis | Indication |
| Quail | Prevention of coccidiosis in growing Bobwhite quail caused by Eimeria dispersa | Indication |
| Quail | Prevention of coccidiosis in growing Bobwhite quail caused by E lettyae | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Coban 60, Coban 90 | Elanco US Inc. | 1 |
| Coban plus Baciferm | Elanco US Inc. | 2 |
| Coban plus BMD | Elanco US Inc. | 2 |
| Rumensin 90 | Elanco US Inc. | 1 |
| Flavomycin / Monensin | Huvepharma EOOD | 2 |
| Coban/TM | Phibro Animal Health Corp. | 2 |
| Rumensin and Tylan | Elanco US Inc. | 2 |
| Sweetlix Rumensin Pressed Block | Ridley USA Inc. | 1 |
| MoorMans Mintrate Blonde Block RU | ADM Animal Nutrition | 1 |
| Pasture Gainer Block 20 R350, Pasture Gainer Block 20 R350 No SE, Pasture Gainer Block 37 R350, Pasture Gainer Block 37 R350 No SE | Purina Animal Nutrition LLC | 1 |
| Cattle Block M | Wildcat Feeds | 1 |
| Aureomycin / Coban | Zoetis Inc. | 2 |
| MGA 100-200 / Rumensin, MGA 100-200 Premix / Rumensin | Zoetis Inc. | 2 |
| MGA 500 plus Rumensin | Zoetis Inc. | 2 |
| Coban | Elanco US Inc. | 1 |
| Albac / Coban | Zoetis Inc. | 2 |
| Coban / BMD | Zoetis Inc. | 2 |
| MGA and Rumensin and Tylan | Zoetis Inc. | 3 |
| BMD / Coban | Elanco US Inc. | 2 |
| Coban / Flavomycin | Elanco US Inc. | 2 |
| BMD / Coban | Zoetis Inc. | 2 |
| Deccox / Rumensin | Zoetis Inc. | 2 |
| Deccox and Rumensin and Tylan | Zoetis Inc. | 3 |
| Optaflexx and Rumensin and Tylan | Elanco US Inc. | 3 |
| Optaflexx plus Rumensin | Elanco US Inc. | 2 |
| Optaflexx and Rumensin and Tylanand MGA | Elanco US Inc. | 4 |
| Optaflexx / Rumensin / MGA | Elanco US Inc. | 3 |
| Zilmax and Rumensin and Tylan | Intervet Inc. | 3 |
| Zilmax plus Rumensin | Intervet Inc. | 2 |
| Zilmax and Rumensin and Tylan and MGA | Intervet Inc. | 4 |
| Zilmax/Rumensin/MGA | Intervet Inc. | 3 |
| Topmax plus Coban | Elanco US Inc. | 2 |
| Pulmotil 90 and Rumensin 90 | Elanco US Inc. | 2 |
| Stafac and Coban | Phibro Animal Health Corp. | 2 |
| Inteprity and Coban | Elanco US Inc. | 2 |
| Coban and LINCOMIX | Zoetis Inc. | 2 |
| Experior and Rumensin and Tylan | Elanco US Inc. | 3 |
| Experior and Rumensin | Elanco US Inc. | 2 |
| Pennitracin MD and Coban | Pharmgate Inc. | 2 |
| ChlorMax / Coban | Zoetis Inc. | 2 |
| Pennchlor / Coban | Pharmgate Inc. | 2 |
| HeifermaX 500 / Rumensin / Tylan | Elanco US Inc. | 3 |
| Heifermax 500 Liquid Premix and Rumensin | Elanco US Inc. | 2 |
| Heifermax / Optaflexx / Rumensin / Tylan | Elanco US Inc. | 4 |
| Heifermax 500/Optaflexx/Rumensin | Elanco US Inc. | 3 |
| Heifermax 500/Zilmax/Rumensin | Elanco US Inc. | 3 |
| Heifermax 500/Zilmax/Rumensin/Tylan | Elanco US Inc. | 4 |
| Rumensin plus Tylovet 100 | Huvepharma EOOD | 2 |
| Deccox, Rumensin, and Tylovet 100 | Huvepharma EOOD | 3 |
| MGA, Rumensin and Tylovet 100 | Huvepharma EOOD | 3 |
| Zilmax/Rumensin/Tylovet 100/MGA | Huvepharma EOOD | 4 |
| Zilmax/Rumensin/Tylovet 100 | Huvepharma EOOD | 3 |
| Actogain 45 plus Rumensin | Zoetis Inc. | 2 |
| Actogain 45/Rumensin/MGA | Zoetis Inc. | 3 |
| Actogain 45/Rumensin/Tylan | Zoetis Inc. | 3 |
| Actogain 45/Rumensin/Tylan/MGA | Zoetis Inc. | 4 |
| Optaflexx 45/Rumensin/Tylovet 100 | Huvepharma EOOD | 3 |
| Optaflexx 45/Rumensin/Tylovet 100/MGA | Huvepharma EOOD | 4 |
| Actogain 45/Rumensin/Tylovet 100/MGA | Zoetis Inc. | 4 |
| Actogain 45/Rumensin/Tylovet 100 | Zoetis Inc. | 3 |
| Tilmovet 90 and Rumensin 90 | Huvepharma EOOD | 2 |
| Monovet 90 | Huvepharma EOOD | 1 |
| Monovet and Tylovet | Huvepharma EOOD | 2 |
| Monovet and Tylan | Huvepharma EOOD | 2 |
| Optaflexxand Monovet and Tylovet | Huvepharma EOOD | 3 |
| Actogain and Monovet and Tylovet | Huvepharma EOOD | 3 |
| Optaflexxand Monovet and Tylan | Huvepharma EOOD | 3 |
| Actogain and Monovet and Tylan | Huvepharma EOOD | 3 |
| Optaflexx and Monovet and Tylovet and MGA | Huvepharma EOOD | 4 |
| Actogain and Monovet and Tylovet and MGA | Huvepharma EOOD | 4 |
| Optaflexx and Monovet and Tylan and MGA | Huvepharma EOOD | 4 |
| Actogain and Monovet and Tylan and MGA | Huvepharma EOOD | 4 |
| Deccox and Monovet | Huvepharma EOOD | 2 |
| Deccox and Monovet and Tylovet | Huvepharma EOOD | 3 |
| Tilmovet and Monovet | Huvepharma EOOD | 2 |
| Pulmotil and Monovet | Huvepharma EOOD | 2 |
| Deccox and Monovet and Tylan | Huvepharma EOOD | 3 |
| MGA and Monovet | Huvepharma EOOD | 2 |
| Actogain and Monovet and MGA | Huvepharma EOOD | 3 |
| MGA and Monovet and Tylovet | Huvepharma EOOD | 3 |
| MGA and Monovet and Tylan | Huvepharma EOOD | 3 |
| Actogain and Monovet | Huvepharma EOOD | 2 |
| Optigrid and Monovet | Huvepharma EOOD | 2 |
| Optigrid and Monovet and Tylovet | Huvepharma EOOD | 3 |
| Optigrid and Monovet and MGA | Huvepharma EOOD | 3 |
| Optigrid and Monovet and Tylovet and MGA | Huvepharma EOOD | 4 |
| CycleGuard and Monovet | Huvepharma EOOD | 1 |
| Optigrid and Monovet and CycleGuard | Huvepharma EOOD | 3 |
| CycleGuard and Monovet and Tylovet | Huvepharma EOOD | 3 |
| Optigrid and Monovet and Tylovet and CycleGuard | Huvepharma EOOD | 4 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEBI:27617 | CHEBI |
| CHEMBL256105 | ChEMBL_ID |
| DB11430 | DRUGBANK_ID |
| D008985 | MESH_DESCRIPTOR_UI |
| C0026408 | UMLSCUI |
| CHEMBL1908308 | ChEMBL_ID |
| 2501 | INN_ID |
| 96160009 | SNOMEDCT_US |
| 22373-78-0 | SECONDARY_CAS_RN |
| D05068 | KEGG_DRUG |
| 441145 | PUBCHEM_CID |
| 1368208 | RXNORM |
| 906O0YJ6ZP | UNII |
Pharmaceutical products:
None