flunixin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| anti-inflammatory, anilinonicotinic acid derivatives | 5545 | 38677-85-9 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D018712 | Analgesics, Non-Narcotic |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| MeSH PA | D058633 | Antipyretics |
| MeSH PA | D018501 | Antirheumatic Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D018689 | Sensory System Agents |
| CHEBI has role | CHEBI:35475 | non-steroidal anti-inflammatory agent |
| CHEBI has role | CHEBI:35493 | anti-pyretic |
| CHEBI has role | CHEBI:35544 | cyclooxygenase inhibitors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cattle | Pyrexia associated with bovine respiratory disease | Indication |
| Cattle | Pain associated with foot rot | Indication |
| Cattle | Pyrexia associated with endotoxemia | Indication |
| Cattle | Pyrexia associated with acute bovine mastitis | Indication |
| Cattle | Inflammation in endotoxemia | Indication |
| Horses | Inflammation and pain associated with musculoskeletal disorders | Indication |
| Horses | Visceral pain associated with colic | Indication |
| Swine | Pyrexia associated with swine respiratory disease | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Banamine , Banamine-S | Intervet Inc. | 1 |
| Banamine Granules | Intervet Inc. | 1 |
| Banamine Paste | Intervet Inc. | 1 |
| Resflor Gold | Intervet Inc. | 2 |
| Hexasol Injection | Norbrook Laboratories, Ltd. | 2 |
| Banamine Transdermal | Intervet Inc. | 1 |
| Flu-Nix | Huvepharma EOOD | 1 |
| Flunixin Meglumine Injection | Elanco US Inc. | 1 |
| Flunixin Meglumine Solution | Zoetis Inc. | 1 |
| Flunixin Injection | Norbrook Laboratories, Ltd. | 1 |
| Flunazine | Bimeda Animal Health Limited | 1 |
| Flunixin Injection - S | Norbrook Laboratories, Ltd. | 1 |
| Flunazine-S | Bimeda Animal Health Limited | 1 |
| Flunazine | Bimeda Animal Health Limited | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | IC50 | 5.10 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| CHEBI:76138 | CHEBI |
| JBO | PDB_CHEM_ID |
| CHEMBL1617398 | ChEMBL_ID |
| C014557 | MESH_SUPPLEMENTAL_RECORD_UI |
| C014558 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB11518 | DRUGBANK_ID |
| 017753 | NDDF |
| 017754 | NDDF |
| C0060502 | UMLSCUI |
| CHEMBL1733447 | ChEMBL_ID |
| 3533 | INN_ID |
| 96173008 | SNOMEDCT_US |
| 96174002 | SNOMEDCT_US |
| 42461-84-7 | SECONDARY_CAS_RN |
| D04215 | KEGG_DRUG |
| 38081 | PUBCHEM_CID |
| 25121 | RXNORM |
| 356IB1O400 | UNII |
Pharmaceutical products:
None