dirlotapide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| microsomal triglyceride transfer protein (MTP) inhibitors | 5527 | 481658-94-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Dogs | Management of obesity | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Slentrol | Zoetis Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Microsomal triglyceride transfer protein large subunit | Cytosolic other | IC50 | 10.95 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| CHEMBL410414 | ChEMBL_ID |
| C521290 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB11399 | DRUGBANK_ID |
| C1958588 | UMLSCUI |
| 8468 | INN_ID |
| 427181005 | SNOMEDCT_US |
| 427351008 | SNOMEDCT_US |
| D03867 | KEGG_DRUG |
| 9917862 | PUBCHEM_CID |
| 1592684 | RXNORM |
| 578H0RMP25 | UNII |
Pharmaceutical products:
None