apatinib 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
tyrosine kinase inhibitors 5211 811803-05-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • rivoceranib
  • apatinib
  • apatinib mesylate
  • apatinib mesilate
  • YN968D1
Apatinib is an oral tyrosine kinase inhibitor approved in China for the treatment of patients with advanced metastatic gastric cancer.
  • Molecular weight: 397.48
  • Formula: C24H23N5O
  • CLOGP: 3.72
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 90.70
  • ALOGS: -4.52
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

apatinib