climbazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5064 38083-17-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • climbazole
  • climbazol
  • Bay-e-6975
Climbazole is a conazole fungicide. It is also use in shampoo and cleaner as an anti-dandruff agents and anti-bacteria agent.
  • Molecular weight: 292.76
  • Formula: C15H17ClN2O2
  • CLOGP: 3.43
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 44.12
  • ALOGS: -3.69
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:35703 Xenobiotic
CHEBI has role CHEBI:78298 environmental contaminants

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Seborrheic dermatitis indication 50563003 DOID:8741




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.35 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Cytochrome P450 3A4 Enzyme IC50 7 CHEMBL

External reference:

IDSource
9N42CW7I54 UNII
C0666079 UMLSCUI
CHEBI:83499 CHEBI
RQH PDB_CHEM_ID
CHEMBL1437764 ChEMBL_ID
37907 PUBCHEM_CID
DB15580 DRUGBANK_ID
4374 INN_ID
C108286 MESH_SUPPLEMENTAL_RECORD_UI
191566 RXNORM
007391 NDDF
711318001 SNOMEDCT_US
714673009 SNOMEDCT_US

Pharmaceutical products:

None