tannic acid Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5039 1401-55-4

Description:

MoleculeDescription

Synonyms:

  • tannic acid
  • tannin
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Feb. 2, 1980 FDA ARMOUR PHARM

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Tyrosine-protein kinase Fyn Kinase IC50 7.66 CHEMBL
Tyrosine-protein kinase Lck Kinase IC50 7.10 CHEMBL
Mitogen-activated protein kinase 1 Kinase IC50 6.73 CHEMBL
Thromboxane-A synthase Enzyme IC50 6.49 CHEMBL
Mitogen-activated protein kinase 14 Kinase IC50 6.43 CHEMBL
Cytochrome P450 1A2 Enzyme IC50 6.04 CHEMBL
cGMP-specific 3',5'-cyclic phosphodiesterase Enzyme IC50 5.33 CHEMBL
3-hydroxy-3-methylglutaryl-coenzyme A reductase Enzyme IC50 5.50 CHEMBL
Mitogen-activated protein kinase 3 Kinase IC50 5.39 CHEMBL
Cytochrome P450 2C9 Enzyme IC50 5.34 CHEMBL
Carbonic anhydrase 6 Enzyme Ki 4.75 CHEMBL
Carbonic anhydrase 2 Enzyme Ki 4.48 CHEMBL
Carbonic anhydrase 1 Enzyme Ki 4.12 CHEMBL
Leukotriene C4 synthase Unclassified IC50 5.57 CHEMBL
Aldose reductase Enzyme IC50 6.46 CHEMBL
Arachidonate 15-lipoxygenase Enzyme IC50 6.57 CHEMBL
Carbonic anhydrase Unclassified Ki 5.03 CHEMBL

External reference:

IDSource
D01959 KEGG_DRUG
4018527 VUID
N0000146849 NUI
C0039294 UMLSCUI
41412001 SNOMEDCT_US
4018527 VANDF
NOCODE MMSL
80867 MMSL
10328 RXNORM
7800 MMSL
001938 NDDF
16129778 PUBCHEM_CID
CHEMBL506247 ChEMBL_ID
DB09372 DRUGBANK_ID
4319 IUPHAR_LIGAND_ID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Nitrotan HUMAN OTC DRUG LABEL 4 11960-0049 AEROSOL, SPRAY 0.02 g TOPICAL OTC monograph not final 9 sections