tannic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	5039	1401-55-4

Description:

Molecule

Description

Synonyms:

tannic acid
tannin

Molecular weight:
Formula:
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Feb. 2, 1980	FDA	ARMOUR PHARM

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Carbonic anhydrase 2	Enzyme	P00918	CAH2_HUMAN		Ki	4.48		CHEMBL
Carbonic anhydrase 1	Enzyme	P00915	CAH1_HUMAN		Ki	4.12		CHEMBL
3-hydroxy-3-methylglutaryl-coenzyme A reductase	Enzyme	P04035	HMDH_HUMAN		IC50	5.50		CHEMBL
Cytochrome P450 2C9	Enzyme	P11712	CP2C9_HUMAN		IC50	5.34		CHEMBL
Cytochrome P450 1A2	Enzyme	P05177	CP1A2_HUMAN		IC50	6.04		CHEMBL
cGMP-specific 3',5'-cyclic phosphodiesterase	Enzyme	O76074	PDE5A_HUMAN		IC50	5.33		CHEMBL
Tyrosine-protein kinase Lck	Kinase	P06239	LCK_HUMAN		IC50	7.10		CHEMBL
Tyrosine-protein kinase Fyn	Kinase	P06241	FYN_HUMAN		IC50	7.66		CHEMBL
Thromboxane-A synthase	Enzyme	P24557	THAS_HUMAN		IC50	6.49		CHEMBL
Carbonic anhydrase 6	Enzyme	P23280	CAH6_HUMAN		Ki	4.75		CHEMBL
Mitogen-activated protein kinase 3	Kinase	P27361	MK03_HUMAN		IC50	5.39		CHEMBL
Mitogen-activated protein kinase 14	Kinase	Q16539	MK14_HUMAN		IC50	6.43		CHEMBL
Mitogen-activated protein kinase 1	Kinase	P28482	MK01_HUMAN		IC50	6.73		CHEMBL
Aldose reductase	Enzyme		ALDR_RAT		IC50	6.46		CHEMBL
Arachidonate 15-lipoxygenase	Enzyme		LOX15_RABIT		IC50	6.57		CHEMBL
Carbonic anhydrase	Enzyme		Q2PCB5_DICLA		Ki	5.03		CHEMBL
Leukotriene C4 synthase	Unclassified		LTC4S_CAVPO		IC50	5.57		CHEMBL

External reference:

ID	Source
28F9E0DJY6	UNII
D01959	KEGG_DRUG
4018527	VUID
N0000146849	NUI
4018527	VANDF
C0039294	UMLSCUI
CHEMBL506247	ChEMBL_ID
16129778	PUBCHEM_CID
DB09372	DRUGBANK_ID
C000726650	MESH_SUPPLEMENTAL_RECORD_UI
4319	IUPHAR_LIGAND_ID
10328	RXNORM
7800	MMSL
80867	MMSL
NOCODE	MMSL
001938	NDDF
41412001	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Nitrotan	HUMAN OTC DRUG LABEL	4	11960-0049	AEROSOL, SPRAY	0.02 g	TOPICAL	OTC monograph not final	9 sections