carboquone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
503 24279-91-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • carboquone
  • carbazilquinone
  • esquinone
An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.
  • Molecular weight: 321.33
  • Formula: C15H19N3O5
  • CLOGP: -0.11
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 1
  • TPSA: 101.71
  • ALOGS: -1.29
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC L01AC03 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
ALKYLATING AGENTS
Ethylene imines
MeSH PA D000477 Alkylating Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018906 Antineoplastic Agents, Alkylating
MeSH PA D009676 Noxae

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.65 acidic
pKa2 6.32 Basic
pKa3 4.29 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01270 KEGG_DRUG
C0006971 UMLSCUI
CHEBI:31356 CHEBI
CHEMBL443014 ChEMBL_ID
DB13677 DRUGBANK_ID
2569 PUBCHEM_CID
3651 INN_ID
1CB0HBT12C UNII
D002225 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None