triaziquone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4372 68-76-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • triaziquone
  • triaziquinone
  • triaziquinonum
  • triaziquon
Alkylating antineoplastic agent used mainly for ovarian tumors. It is toxic to skin, gastrointestinal tract, bone marrow and kidneys.
  • Molecular weight: 231.26
  • Formula: C12H13N3O2
  • CLOGP: -0.14
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 0
  • TPSA: 43.17
  • ALOGS: -0.49
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC L01AC02 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
ALKYLATING AGENTS
Ethylene imines
MeSH PA D000477 Alkylating Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018906 Antineoplastic Agents, Alkylating
MeSH PA D009676 Noxae
CHEBI has role CHEBI:35610 antineoplastic agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.75 Basic
pKa2 2.24 Basic
pKa3 1.55 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07254 KEGG_DRUG
C0040878 UMLSCUI
CHEBI:27090 CHEBI
CHEMBL313302 ChEMBL_ID
DB13304 DRUGBANK_ID
1720 INN_ID
F3D5D9P25I UNII
6235 PUBCHEM_CID
D014228 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None