tyloxapol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4738 25301-02-4

Description:

MoleculeDescription

Synonyms:

  • tyloxapol
  • alevaire
non-ionic detergent with surface-active properties; incompatible with metals; surfactant also used in inhalation therapy; N1 is from CA Vol 90 Form Index; N1 in Chemline is same as synonym 8
  • Molecular weight:
  • Formula: None
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
5 mg Inhal.solution

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Aug. 2, 1990 FDA GLAXOSMITHKLINE

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R05CA01 RESPIRATORY SYSTEM
COUGH AND COLD PREPARATIONS
EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
Expectorants
MeSH PA D003902 Detergents
MeSH PA D013501 Surface-Active Agents
CHEBI has role CHEBI:35195 surfactant
CHEBI has role CHEBI:35222 inhibitor
CHEBI has role CHEBI:68495 Type I cell-death inducers
CHEBI has role CHEBI:75324 excipient

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Respiratory distress syndrome in the newborn indication 46775006




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D03261 KEGG_DRUG
4019371 VUID
N0000179276 NUI
4019371 VANDF
CHEBI:141517 CHEBI
CHEMBL1201548 ChEMBL_ID
C016811 MESH_SUPPLEMENTAL_RECORD_UI
1435 INN_ID
DB06439 DRUGBANK_ID
Y27PUL9H56 UNII
38998 RXNORM
5650 MMSL
000719 NDDF
108888009 SNOMEDCT_US
386931000 SNOMEDCT_US
C0077539 UMLSCUI
71388 PUBCHEM_CID

Pharmaceutical products:

None