pyrethrins 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4700 8003-34-7

Description:

MoleculeDescription

Synonyms:

  • pyrethrins
  • pyrethrum oleo resin
  • pyrethrum extract
  • pyrethrum
  • pyrellin
The active insecticidal constituent of CHRYSANTHEMUM CINERARIIFOLIUM flowers. Pyrethrin I is the pyretholone ester of chrysanthemummonocarboxylic acid and pyrethrin II is the pyretholone ester of chrysanthemumdicarboxylic acid monomethyl ester.
  • Molecular weight: 1377.80
  • Formula: C84H112O16
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 69.67
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
March 7, 2000 FDA BAYER HEALTHCARE LLC

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P03AC01 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES
Pyrethrines, incl. synthetic compounds
ATC P03AC51 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES
Pyrethrines, incl. synthetic compounds
MeSH PA D007306 Insecticides
MeSH PA D010575 Pesticides
CHEBI has role CHEBI:22917 phytogenic insecticide
CHEBI has role CHEBI:35442 antiparasitic agent

Related Drugs by ATC class:

P03AC Pyrethrines, incl. synthetic compounds 3 drugs
bioallethrinpermethrinphenothrin

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Pediculosis corporis indication 25188002 DOID:5513
Infestation by Phthirus pubis indication 71011005 DOID:13760
Pediculosis capitis indication 81000006 DOID:5501




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019243 VANDF
4019481 VANDF
C0034245 UMLSCUI
CHEBI:39098 CHEBI
CHEMBL2108766 ChEMBL_ID
60202781 PUBCHEM_CID
DB11087 DRUGBANK_ID
CHEMBL563221 ChEMBL_ID
D011722 MESH_DESCRIPTOR_UI
1232405 RXNORM
5391 MMSL
003008 NDDF
256038001 SNOMEDCT_US
400602009 SNOMEDCT_US
411383009 SNOMEDCT_US
45620004 SNOMEDCT_US
ZUM06L90GV UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
RID Lice Killing HUMAN OTC DRUG LABEL 2 0280-9000 SHAMPOO 3.30 mg TOPICAL OTC monograph final 15 sections
Walgreens Lice Killing HUMAN OTC DRUG LABEL 2 0363-1253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 14 sections
Major Lice Killing HUMAN OTC DRUG LABEL 2 0904-7349 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
Lice No More Lice Killing HUMAN OTC DRUG LABEL 2 11383-001 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
Lice Killing HUMAN OTC DRUG LABEL 2 11383-253 SHAMPOO 0.33 g TOPICAL OTC monograph final 15 sections
Lice Killing HUMAN OTC DRUG LABEL 2 11383-310 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 14 sections
ABC Lice Killing HUMAN OTC DRUG LABEL 2 11383-312 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
ABC Lice Killing HUMAN OTC DRUG LABEL 2 11383-312 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
Rite Aid Lice Killing HUMAN OTC DRUG LABEL 2 11822-6616 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
Select Brand Lice Killing HUMAN OTC DRUG LABEL 2 15127-680 SHAMPOO 0.33 g TOPICAL OTC monograph final 15 sections
ZAP Lice Killing HUMAN OTC DRUG LABEL 2 24286-0253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 14 sections
Quita Piojos Lice Killing HUMAN OTC DRUG LABEL 2 24286-1253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 14 sections
Kroger Lice Killing HUMAN OTC DRUG LABEL 2 30142-253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
GNP Lice Killing HUMAN OTC DRUG LABEL 2 46122-759 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
Mata Piojos Lice HUMAN OTC DRUG LABEL 2 48201-006 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 12 sections
Mata Piojos Lice HUMAN OTC DRUG LABEL 2 48201-006 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 12 sections
GoodSense Lice Killing HUMAN OTC DRUG LABEL 2 50804-253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
GoodSense Lice Killing HUMAN OTC DRUG LABEL 2 50804-253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
LIENDREX HUMAN OTC DRUG LABEL 2 53145-308 SHAMPOO 0.30 g TOPICAL OTC Monograph Drug 13 sections
Discount Drug Mart Lice Killing HUMAN OTC DRUG LABEL 2 53943-253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
Family Wellness Lice Killing HUMAN OTC DRUG LABEL 2 55319-253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
El Piojito Lice Killing HUMAN OTC DRUG LABEL 2 55758-253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
medi and lice lice killing HUMAN OTC DRUG LABEL 2 58180-220 SHAMPOO 0.33 g TOPICAL OTC monograph final 14 sections
Vanalice HUMAN OTC DRUG LABEL 2 58809-650 GEL 3 mg TOPICAL OTC Monograph Drug 15 sections
Vida Mia Lice Killing HUMAN OTC DRUG LABEL 2 59970-253 SHAMPOO 0.33 g TOPICAL OTC monograph final 15 sections
Pronto Plus Lice Killing HUMAN OTC DRUG LABEL 2 63736-210 SHAMPOO 0.00 mL TOPICAL OTC MONOGRAPH FINAL 14 sections
Quality Choice Lice Killing HUMAN OTC DRUG LABEL 2 63868-007 SHAMPOO 0.33 g TOPICAL OTC monograph final 15 sections
Best Choice Lice Killing HUMAN OTC DRUG LABEL 2 63941-253 SHAMPOO 0.33 g TOPICAL OTC monograph final 15 sections
Lice Killing HUMAN OTC DRUG LABEL 2 68016-253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections
Lice Killing HUMAN OTC DRUG LABEL 2 68016-253 SHAMPOO 0.33 g TOPICAL OTC Monograph Drug 15 sections