picodralazine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antihypertensives, hydrazinephthalazine derivatives 4689 17692-43-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • picodralazine
  • picodralazine hydrochloride
  • picodralazine HCl
  • Molecular weight: 251.29
  • Formula: C14H13N5
  • CLOGP: 1.74
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 76.72
  • ALOGS: -3.38
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C02LG03 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION
Hydrazinophthalazine derivatives and diuretics
ATC C02LG73 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION
Hydrazinophthalazine derivatives and diuretics

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.5 Basic
pKa2 5.37 Basic
pKa3 3.65 Basic
pKa4 3.11 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C1882375 UMLSCUI
CHEBI:136022 CHEBI
CHEMBL1968696 ChEMBL_ID
2405 INN_ID
O9D004V63I UNII
71890 PUBCHEM_CID

Pharmaceutical products:

None