benzoin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4663 | 119-53-9 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide and used in organic syntheses. This should not be confused with benzoin gum from STYRAX.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:78444 | Alpha-carboxylesterase inhibitor |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Laryngeal papillomatosis | indication | 232457008 | |
| Condyloma acuminatum | indication | 240542006 | DOID:11168 |
| Disorder of keratinization | indication | 277905003 | |
| Superficial Benign Epitheliomatosis | indication |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.6 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Liver carboxylesterase 1 | Enzyme | Ki | 5.14 | CHEMBL | |||||
| Cocaine esterase | Enzyme | Ki | 5.65 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D03091 | KEGG_DRUG |
| 4019093 | VUID |
| N0000147353 | NUI |
| 4019093 | VANDF |
| CHEBI:17682 | CHEBI |
| CHEMBL190677 | ChEMBL_ID |
| DB14020 | DRUGBANK_ID |
| 1406 | RXNORM |
| 4258 | MMSL |
| 4820 | MMSL |
| 001921 | NDDF |
| 391828004 | SNOMEDCT_US |
| C0005070 | UMLSCUI |
| D001573 | MESH_DESCRIPTOR_UI |
| 8400 | PUBCHEM_CID |
| L7J6A1NE81 | UNII |
Pharmaceutical products:
None