methylatropine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| atropine derivatives | 4660 | 31610-87-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 3 | mg | O |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A03BB02 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS BELLADONNA AND DERIVATIVES, PLAIN Belladonna alkaloids, semisynthetic, quaternary ammonium compounds |
| MeSH PA | D010276 | Parasympatholytics |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.24 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | GPCR | Kd | 8.57 | CHEMBL | |||||
| Muscarinic acetylcholine receptor M1 | GPCR | Kd | 8.60 | CHEMBL | |||||
| Muscarinic acetylcholine receptor M3 | GPCR | Kd | 8.59 | CHEMBL | |||||
| Muscarinic acetylcholine receptor DM1 | GPCR | Ki | 8.62 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D01077 | KEGG_DRUG |
| 4018467 | VANDF |
| CHEBI:134749 | CHEBI |
| CHEMBL1179176 | ChEMBL_ID |
| CHEMBL1187724 | ChEMBL_ID |
| C006649 | MESH_SUPPLEMENTAL_RECORD_UI |
| 52-88-0 | SECONDARY_CAS_RN |
| DB13833 | DRUGBANK_ID |
| 001716 | NDDF |
| 006113 | NDDF |
| 391795000 | SNOMEDCT_US |
| C0066332 | UMLSCUI |
| CHEMBL516476 | ChEMBL_ID |
| CHEMBL2146143 | ChEMBL_ID |
| 5861 | PUBCHEM_CID |
| 436 | INN_ID |
| 80719I460H | UNII |
Pharmaceutical products:
None