dodecanoic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4642 143-07-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dodecanoic acid
  • lauric acid
  • laurostearic acid
  • vulvic acid
  • Molecular weight: 200.32
  • Formula: C12H24O2
  • CLOGP: 5.10
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 1
  • TPSA: 37.30
  • ALOGS: -4.30
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:33282 bactericides
CHEBI has role CHEBI:76924 plant metabolites
CHEBI has role CHEBI:84735 algal metabolites

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.76 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Peroxisome proliferator-activated receptor alpha Nuclear hormone receptor IC50 4.52 CHEMBL
Peroxisome proliferator-activated receptor gamma Nuclear hormone receptor IC50 4.52 CHEMBL
Peroxisome proliferator-activated receptor delta Nuclear hormone receptor IC50 4.52 CHEMBL
Free fatty acid receptor 1 GPCR EC50 6.12 CHEMBL
G-protein coupled receptor 84 GPCR AGONIST EC50 5.05 IUPHAR

External reference:

IDSource
CHEBI:30805 CHEBI
LAU PDB_CHEM_ID
CHEMBL108766 ChEMBL_ID
C030358 MESH_SUPPLEMENTAL_RECORD_UI
5534 IUPHAR_LIGAND_ID
DB03017 DRUGBANK_ID
3893 PUBCHEM_CID
1363435 RXNORM
006214 NDDF
C0023139 UMLSCUI
1160N9NU9U UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Vitafol Plus HUMAN PRESCRIPTION DRUG LABEL 17 0642-0092 CAPSULE, LIQUID FILLED 60 mg ORAL UNAPPROVED DRUG OTHER 13 sections