levomenol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4619 23089-26-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • levomenol
  • kamillosan
  • (-)-alpha-Bisabolol
  • bisabolol
drug combination containing chamomile and bisabolol; used to treat dermatitis
  • Molecular weight: 222.37
  • Formula: C15H26O
  • CLOGP: 4.66
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 20.23
  • ALOGS: -3.48
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Neuronal acetylcholine receptor subunit alpha-7 Ion channel IC50 5.51 CHEMBL
Signal transducer and activator of transcription 3 Transcription factor IC50 4.14 CHEMBL

External reference:

IDSource
4020600 VUID
N0000179054 NUI
4020600 VANDF
CHEBI:125 CHEBI
CHEMBL1096927 ChEMBL_ID
C056251 MESH_SUPPLEMENTAL_RECORD_UI
C004497 MESH_SUPPLEMENTAL_RECORD_UI
3667 INN_ID
DB13153 DRUGBANK_ID
24WE03BX2T UNII
442343 PUBCHEM_CID
19461 RXNORM
006445 NDDF
010315 NDDF
768492006 SNOMEDCT_US
C0053774 UMLSCUI
CHEMBL1561544 ChEMBL_ID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
INTENSE MULTI AMPOULE BALM VITA C HUMAN OTC DRUG LABEL 2 51346-539 LIQUID 0.05 g TOPICAL unapproved drug other 8 sections
Seamoms Tamanu Oil Mist HUMAN OTC DRUG LABEL 2 70889-920 OIL 0.50 g TOPICAL unapproved drug other 9 sections
PurpleU BAOBAB FACE HUMAN OTC DRUG LABEL 1 71732-020 OIL 0.07 g TOPICAL unapproved drug other 8 sections