calcium phosphate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4441	7758-87-4

Description:

Molecule	Description
Synonyms: calcium phosphate tribasic calcium phosphate tricalcium phosphate	refers to unspecified salt; see other calcium phosphates Molecular weight: 310.17 Formula: Ca3O8P2 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 86.25 ALOGS: ROTB: None

Molecule

Description

Synonyms:

calcium phosphate
tribasic calcium phosphate
tricalcium phosphate

refers to unspecified salt; see other calcium phosphates

Molecular weight: 310.17
Formula: Ca3O8P2
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 86.25
ALOGS:
ROTB: None

Drug dosage:

Dose	Unit	Route
2	g	O

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Atrioventricular conduction time shortened	19.17	15.52	3	4899	21	63484099
Blood electrolytes increased	18.13	15.52	3	4899	31	63484089
Rectal lesion	16.58	15.52	3	4899	54	63484066
Elliptocytosis	15.84	15.52	3	4899	70	63484050

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Regurgitation	44.44	19.85	12	2253	1687	34952979
Dyspepsia	41.09	19.85	27	2238	36705	34917961
Oropharyngeal discomfort	32.93	19.85	11	2254	3185	34951481
Vitamin B12 deficiency	30.43	19.85	11	2254	4020	34950646
Periarthritis	29.97	19.85	8	2257	1076	34953590
Eructation	28.72	19.85	11	2254	4720	34949946

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Regurgitation	32.91	16.17	11	5915	2776	79735686
Dyspepsia	30.57	16.17	39	5887	108648	79629814
Vitamin B12 deficiency	28.95	16.17	13	5913	7228	79731234
Oropharyngeal discomfort	22.85	16.17	11	5915	7155	79731307
Eructation	21.16	16.17	12	5914	10897	79727565
Atrioventricular conduction time shortened	19.29	16.17	3	5923	21	79738441

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A12AA01	ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS CALCIUM Calcium
MeSH PA	D001672	Biocompatible Materials

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hypocalcemia	indication	5291005
Osteoporosis	indication	64859006	DOID:11476
Postmenopausal osteoporosis	indication	102447009
Pregnancy, function	indication	289908002
Breastfeeding (mother)	indication	413712001
Prevention of Fetal Neural Tube Defects during Pregnancy	off-label use
Poisoning by digitalis glycoside	contraindication	12876009
Peptic ulcer	contraindication	13200003	DOID:750
Constipation	contraindication	14760008	DOID:2089
Hyperphosphatemia	contraindication	20165001	DOID:0050459
Gastroenteritis	contraindication	25374005	DOID:2326
Hypervitaminosis D	contraindication	27712000	DOID:9971
Sarcoidosis	contraindication	31541009	DOID:11335
Dehydration	contraindication	34095006
Depressive disorder	contraindication	35489007
Hemosiderosis	contraindication	39011001	DOID:12119
Mental handicap	contraindication	47437004
Systemic lupus erythematosus	contraindication	55464009	DOID:9074
Schizophrenia	contraindication	58214004	DOID:5419
Hemolytic anemia	contraindication	61261009	DOID:583
Ulcerative colitis	contraindication	64766004	DOID:8577
Hypercalcemia	contraindication	66931009	DOID:12678
Hyperparathyroidism	contraindication	66999008	DOID:13543
Hypercalciuria	contraindication	71938000
Diabetes mellitus	contraindication	73211009	DOID:9351
Autoimmune disease	contraindication	85828009
Kidney disease	contraindication	90708001	DOID:557
Kidney stone	contraindication	95570007
Neoplasm of prostate	contraindication	126906006	DOID:10283
Disease of liver	contraindication	235856003	DOID:409
Arteriosclerosis obliterans	contraindication	361133006	DOID:5160
Diverticular disease	contraindication	397881000
Hemochromatosis	contraindication	399187006	DOID:2352
Repeated Blood Transfusions	contraindication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
4019973	VUID
N0000148058	NUI
1306-06-5	SECONDARY_CAS_RN
4019973	VANDF
4020044	VANDF
C0006711	UMLSCUI
CHEBI:9679	CHEBI
CHEMBL2107567	ChEMBL_ID
CHEMBL2106566	ChEMBL_ID
CHEMBL2218916	ChEMBL_ID
DB11348	DRUGBANK_ID
C020243	MESH_SUPPLEMENTAL_RECORD_UI
C018392	MESH_SUPPLEMENTAL_RECORD_UI
24456	PUBCHEM_CID
1919	RXNORM
17895	MMSL
41493	MMSL
41494	MMSL
4327	MMSL
4328	MMSL
NOCODE	MMSL
d03803	MMSL
005047	NDDF
419939009	SNOMEDCT_US
44044007	SNOMEDCT_US
91D9GV0Z28	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Prenaissance	HUMAN PRESCRIPTION DRUG LABEL	9	42192-341	CAPSULE, LIQUID FILLED	160 mg	ORAL	UNAPPROVED DRUG OTHER	10 sections
Dairy Allergen Mix	HUMAN OTC DRUG LABEL	38	43742-1277	LIQUID	6 [hp_C]	ORAL	unapproved drug other	9 sections
CS Bone	HUMAN OTC DRUG LABEL	11	57955-0211	LIQUID	10 [hp_X]	ORAL	unapproved homeopathic	9 sections
Exoden Sensitive	HUMAN OTC DRUG LABEL	2	70602-006	PASTE	19 g	TOPICAL	unapproved drug other	8 sections
KUNDAL Sensitive Dental Care Tooth (Apple Chamomile Mint)	HUMAN OTC DRUG LABEL	1	74773-0040	PASTE	17 g	DENTAL	unapproved drug other	7 sections
DIO Enamel Coating Pen Pro Tooth	HUMAN OTC DRUG LABEL	3	75902-6001	PASTE, DENTIFRICE	20 g	DENTAL	unapproved drug other	7 sections