acediasulfone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
44 80-03-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acediasulfone
antibacterial drug for treatment of ear infections
  • Molecular weight: 306.34
  • Formula: C14H14N2O4S
  • CLOGP: 1.13
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 3
  • TPSA: 109.49
  • ALOGS: -3.23
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.36 acidic
pKa2 2.03 Basic
pKa3 1.33 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Aldose reductase Enzyme IC50 4.70 CHEMBL
Dihydropteroate synthetase, putative Unclassified IC50 4.75 CHEMBL
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase Unclassified IC50 4.75 CHEMBL

External reference:

IDSource
C1958507 UMLSCUI
CHEMBL48396 ChEMBL_ID
DB08926 DRUGBANK_ID
C521214 MESH_SUPPLEMENTAL_RECORD_UI
66451 PUBCHEM_CID
30YP2YHH8W UNII

Pharmaceutical products:

None