lithium carbonate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4207 554-13-2

Description:

MoleculeDescription

Synonyms:

  • lithium carbonate
  • carbonic acid, dilithium salt
  • dilithium carbonate
A lithium salt, classified as a mood-stabilizing agent. Lithium ion alters the metabolism of BIOGENIC MONOAMINES in the CENTRAL NERVOUS SYSTEM, and affects multiple neurotransmission systems.
  • Molecular weight: 73.89
  • Formula: CLi2O3
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 63.19
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
24 mmol O

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 3 Benet LZ, Broccatelli F, Oprea TI
S (Water solubility) 13 mg/mL Benet LZ, Broccatelli F, Oprea TI
EoM (Fraction excreted unchanged in urine) 95 % Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose) 116.00 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
April 6, 1970 FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Toxicity to various agents 962.36 14.83 812 32213 287034 90308388
Antipsychotic drug level increased 748.06 14.83 190 32835 3589 90591833
Tremor 666.15 14.83 505 32520 152668 90442754
Drug interaction 487.38 14.83 550 32475 275903 90319519
Sopor 436.42 14.83 202 32823 24442 90570980
Extrapyramidal disorder 430.18 14.83 177 32848 16126 90579296
Drug abuse 421.82 14.83 300 32725 82047 90513375
Neuroleptic malignant syndrome 405.46 14.83 166 32859 14930 90580492
Antipsychotic drug level above therapeutic 372.03 14.83 89 32936 1295 90594127
Nephrogenic diabetes insipidus 337.99 14.83 77 32948 893 90594529
Mania 279.11 14.83 125 32900 13999 90581423
Agitation 257.98 14.83 206 32819 66892 90528530
Intentional self-injury 244.05 14.83 145 32880 29189 90566233
Somnolence 242.79 14.83 338 32687 208746 90386676
Coma 233.44 14.83 201 32824 72431 90522991
Dysarthria 226.09 14.83 175 32850 54307 90541115
Confusional state 223.52 14.83 457 32568 385748 90209674
Parkinsonism 205.34 14.83 101 32924 13964 90581458
Overdose 183.02 14.83 255 32770 157454 90437968
Altered state of consciousness 182.65 14.83 124 32901 31408 90564014
Suicide attempt 174.96 14.83 174 32851 75225 90520197
Suicidal ideation 166.88 14.83 168 32857 73687 90521735
Hyperparathyroidism 155.91 14.83 55 32970 3282 90592140
Ataxia 154.80 14.83 91 32934 17951 90577471
Delusion 154.60 14.83 83 32942 13757 90581665
Disorientation 151.76 14.83 127 32898 43987 90551435
Tardive dyskinesia 149.22 14.83 75 32950 10855 90584567
Hallucination, auditory 140.82 14.83 82 32943 15893 90579529
Serotonin syndrome 140.62 14.83 114 32911 37773 90557649
Sedation 138.11 14.83 125 32900 48046 90547376
Infusion related reaction 137.44 14.83 3 33022 416777 90178645
Polyuria 137.38 14.83 69 32956 9971 90585451
Bradyphrenia 133.46 14.83 62 32963 7550 90587872
Muscle rigidity 132.92 14.83 76 32949 14233 90581189
Pain 132.61 14.83 102 32923 996239 89599183
Acute kidney injury 131.38 14.83 331 32694 320056 90275366
Hypernatraemia 126.94 14.83 64 32961 9323 90586099
Encephalopathy 126.29 14.83 117 32908 46327 90549095
Body tinea 126.08 14.83 42 32983 2106 90593316
Drug level increased 123.54 14.83 93 32932 27669 90567753
Inhibitory drug interaction 121.09 14.83 45 32980 3118 90592304
Diabetes insipidus 116.78 14.83 44 32981 3168 90592254
Akathisia 116.51 14.83 64 32961 11095 90584327
Cerebellar syndrome 115.72 14.83 46 32979 3826 90591596
Disturbance in attention 115.36 14.83 112 32913 46997 90548425
Systemic lupus erythematosus 114.14 14.83 4 33021 361892 90233530
Aggression 113.51 14.83 87 32938 26581 90568841
Intentional overdose 112.17 14.83 154 32871 93680 90501742
Salivary hypersecretion 111.39 14.83 58 32967 9034 90586388
Joint swelling 110.98 14.83 24 33001 503276 90092146
Poisoning deliberate 110.42 14.83 71 32954 16415 90579007
Electrocardiogram QT prolonged 105.39 14.83 131 32894 72325 90523097
Glossodynia 103.46 14.83 3 33022 321776 90273646
Infection susceptibility increased 101.40 14.83 42 32983 3884 90591538
Depressed level of consciousness 100.16 14.83 128 32897 72656 90522766
Glucose tolerance impaired 98.00 14.83 51 32974 7934 90587488
Psychotic disorder 97.38 14.83 85 32940 31145 90564277
Restlessness 97.13 14.83 90 32935 35630 90559792
Arthralgia 96.85 14.83 85 32940 778437 89816985
Wound 96.76 14.83 3 33022 302977 90292445
Swelling 96.49 14.83 18 33007 419040 90176382
Myoclonus 96.08 14.83 69 32956 19099 90576323
Arthropathy 95.23 14.83 11 33014 366231 90229191
Abdominal discomfort 93.31 14.83 29 32996 477299 90118123
Dyspnoea 91.75 14.83 112 32913 880843 89714579
Hypersensitivity 89.99 14.83 27 32998 454650 90140772
Rheumatoid arthritis 89.21 14.83 13 33012 362601 90232821
Polydipsia 88.56 14.83 39 32986 4192 90591230
Treatment failure 84.59 14.83 7 33018 303921 90291501
Bipolar disorder 84.19 14.83 48 32977 8937 90586485
Dyskinesia 84.12 14.83 84 32941 36450 90558972
Completed suicide 82.83 14.83 171 32854 144887 90450535
Speech disorder 82.18 14.83 92 32933 45493 90549929
Contraindicated product administered 79.85 14.83 11 33014 320128 90275294
Drug intolerance 79.25 14.83 32 32993 447559 90147863
Alopecia 78.95 14.83 41 32984 495030 90100392
Electroencephalogram abnormal 76.93 14.83 35 32990 4061 90591361
Pyramidal tract syndrome 76.56 14.83 21 33004 538 90594884
Hyperreflexia 74.56 14.83 40 32985 6617 90588805
Stomatitis 72.02 14.83 8 33017 274690 90320732
Psychomotor skills impaired 71.73 14.83 30 32995 2842 90592580
Sinus bradycardia 71.47 14.83 55 32970 16897 90578525
Hypomania 71.42 14.83 43 32982 8854 90586568
Hyperlipidaemia 70.69 14.83 62 32963 22854 90572568
Nasopharyngitis 70.61 14.83 30 32995 407074 90188348
Poor quality sleep 70.60 14.83 64 32961 24629 90570793
Hypothyroidism 67.73 14.83 90 32935 53037 90542385
Behaviour disorder 66.79 14.83 33 32992 4602 90590820
Sinusitis 66.72 14.83 21 33004 343067 90252355
Schizophrenia 66.43 14.83 50 32975 14864 90580558
Bradykinesia 65.59 14.83 37 32988 6751 90588671
Abnormal behaviour 65.39 14.83 59 32966 22569 90572853
Urticaria 64.76 14.83 17 33008 312717 90282705
Psoriatic arthropathy 64.24 14.83 5 33020 228330 90367092
Blister 63.02 14.83 9 33016 254989 90340433
Hypercalcaemia 59.83 14.83 68 32957 34172 90561250
Impaired work ability 59.04 14.83 52 32973 19274 90576148
Impaired healing 58.50 14.83 8 33017 234191 90361231
Purpura 58.08 14.83 46 32979 14732 90580690
Antipsychotic drug level below therapeutic 57.52 14.83 15 33010 315 90595107
Mental status changes 57.43 14.83 76 32949 44603 90550819
Poisoning 56.89 14.83 46 32979 15171 90580251
Hepatic enzyme increased 55.82 14.83 31 32994 360705 90234717
Peripheral swelling 55.10 14.83 42 32983 413064 90182358
Impaired quality of life 54.73 14.83 54 32971 23090 90572332
Dystonia 52.87 14.83 46 32979 16773 90578649
Mutism 52.81 14.83 21 33004 1748 90593674
Neurotoxicity 52.47 14.83 51 32974 21416 90574006
Blood creatine phosphokinase increased 51.85 14.83 63 32962 33960 90561462
Fibromyalgia 51.62 14.83 7 33018 206262 90389160
International normalised ratio abnormal 51.35 14.83 26 32999 3819 90591603
Pruritus 50.98 14.83 74 32951 541451 90053971
Aphasia 50.73 14.83 70 32955 42742 90552680
Psychomotor hyperactivity 50.61 14.83 40 32985 12773 90582649
Catatonia 50.51 14.83 30 32995 6026 90589396
Therapeutic product effect decreased 50.48 14.83 19 33006 277552 90317870
Logorrhoea 50.26 14.83 23 33002 2704 90592718
Liver injury 50.12 14.83 3 33022 170564 90424858
Protein C increased 50.03 14.83 10 33015 58 90595364
Neutrophil count increased 49.15 14.83 47 32978 19343 90576079
White blood cell count increased 49.08 14.83 88 32937 67153 90528269
Gestational diabetes 48.29 14.83 36 32989 10546 90584876
Lower respiratory tract infection 47.55 14.83 16 33009 250643 90344779
Irritable bowel syndrome 47.51 14.83 9 33016 207439 90387983
Depression 47.43 14.83 226 32799 300375 90295047
Haemodialysis 47.33 14.83 33 32992 8714 90586708
Faecaloma 46.52 14.83 35 32990 10396 90585026
Irritability 46.35 14.83 61 32964 35601 90559821
Discomfort 46.30 14.83 21 33004 274314 90321108
Cogwheel rigidity 46.02 14.83 20 33005 2082 90593340
Off label use 44.45 14.83 229 32796 1102023 89493399
Blood prolactin increased 43.97 14.83 23 33002 3614 90591808
Dialysis 43.96 14.83 35 32990 11294 90584128
Hallucination 43.95 14.83 83 32942 65876 90529546
Bone density decreased 43.88 14.83 42 32983 17303 90578119
Persecutory delusion 43.74 14.83 22 33003 3186 90592236
Psychiatric symptom 43.62 14.83 29 32996 7089 90588333
Hypokinesia 43.53 14.83 40 32985 15657 90579765
Drug reaction with eosinophilia and systemic symptoms 43.46 14.83 65 32960 42693 90552729
Treatment noncompliance 43.39 14.83 72 32953 51655 90543767
Bone abscess 43.29 14.83 13 33012 463 90594959
Drug hypersensitivity 42.99 14.83 64 32961 463545 90131877
Lethargy 42.75 14.83 80 32945 63059 90532363
Mobility decreased 42.61 14.83 19 33006 250715 90344707
Rhabdomyolysis 42.53 14.83 71 32954 51185 90544237
Infection 41.99 14.83 42 32983 362052 90233370
Cognitive disorder 40.98 14.83 83 32942 69324 90526098
Product use issue 40.92 14.83 36 32989 329883 90265539
Psychomotor retardation 40.66 14.83 24 33001 4765 90590657
Hallucination, visual 40.57 14.83 46 32979 23046 90572376
Wheezing 40.52 14.83 18 33007 238062 90357360
Choreoathetosis 40.50 14.83 13 33012 579 90594843
Euphoric mood 40.49 14.83 25 33000 5384 90590038
Ill-defined disorder 40.31 14.83 9 33016 184882 90410540
Bradycardia 40.02 14.83 92 32933 83755 90511667
Paranoia 39.96 14.83 35 32990 12873 90582549
Gastrointestinal disorder 39.77 14.83 22 33003 256665 90338757
Mental impairment 39.51 14.83 39 32986 16681 90578741
Hypoaesthesia 39.31 14.83 34 32991 314176 90281246
Induced abortion failed 39.05 14.83 10 33015 195 90595227
Leukocytosis 38.73 14.83 52 32973 30938 90564484
Electrocardiogram T wave abnormal 38.32 14.83 19 33006 2669 90592753
Chronic kidney disease 38.32 14.83 67 32958 50124 90545298
Psychiatric decompensation 37.75 14.83 17 33008 1926 90593496
Depressed mood 36.99 14.83 66 32959 50156 90545266
Pneumonia 36.76 14.83 115 32910 637944 89957478
Osteoarthritis 36.25 14.83 13 33012 195717 90399705
Cough 36.10 14.83 49 32976 368913 90226509
Impaired self-care 36.10 14.83 16 33009 1746 90593676
Intentional product use issue 35.97 14.83 17 33008 216875 90378547
Blood urea increased 34.94 14.83 49 32976 30364 90565058
Drug eruption 34.81 14.83 53 32972 35354 90560068
Withdrawal syndrome 34.79 14.83 42 32983 22482 90572940
Skin disorder 34.76 14.83 54 32971 36652 90558770
Musculoskeletal pain 34.14 14.83 10 33015 171241 90424181
Hypertonia 34.02 14.83 22 33003 5133 90590289
Toxic encephalopathy 34.02 14.83 27 32998 8672 90586750
Rash 33.96 14.83 162 32863 795938 89799484
Death 33.37 14.83 73 32952 456478 90138944
Bundle branch block right 32.89 14.83 22 33003 5431 90589991
Language disorder 32.72 14.83 17 33008 2635 90592787
Myasthenic syndrome 32.63 14.83 10 33015 382 90595040
Hypothermia 32.55 14.83 34 32991 15541 90579881
Status epilepticus 32.15 14.83 37 32988 18837 90576585
Pain in extremity 32.14 14.83 73 32952 450456 90144966
Febrile neutropenia 32.02 14.83 9 33016 158340 90437082
Granulocytopenia 31.85 14.83 23 33002 6418 90589004
Bursitis 31.70 14.83 5 33020 131649 90463773
Anxiety 31.54 14.83 207 32818 309565 90285857
Disease progression 31.48 14.83 9 33016 156606 90438816
Paraesthesia 31.41 14.83 27 32998 250299 90345123
Parathyroid tumour benign 31.07 14.83 12 33013 924 90594498
Persistent depressive disorder 30.96 14.83 13 33012 1244 90594178
Therapeutic product effect incomplete 30.94 14.83 16 33009 193880 90401542
Cardio-respiratory arrest 30.93 14.83 70 32955 63070 90532352
Hyperthermia malignant 30.55 14.83 13 33012 1285 90594137
Headache 30.48 14.83 187 32838 862559 89732863
Stupor 30.41 14.83 21 33004 5461 90589961
Apathy 30.36 14.83 28 32997 11012 90584410
Fatigue 30.35 14.83 272 32753 1153751 89441671
Alcohol interaction 29.86 14.83 14 33011 1740 90593682
Myocarditis septic 29.84 14.83 6 33019 36 90595386
Blood sodium increased 29.81 14.83 17 33008 3165 90592257
Reflexes abnormal 29.65 14.83 11 33014 758 90594664
Ileus paralytic 29.44 14.83 20 33005 5065 90590357
Lung disorder 29.42 14.83 9 33016 149874 90445548
Psychotic symptom 29.39 14.83 15 33010 2241 90593181
Asthma 29.33 14.83 27 32998 242133 90353289
Encopresis 29.05 14.83 7 33018 105 90595317
Gait disturbance 28.94 14.83 178 32847 260318 90335104
Deprescribing error 28.68 14.83 6 33019 45 90595377
Galactorrhoea 28.54 14.83 19 33006 4653 90590769
Urinary incontinence 28.48 14.83 50 32975 37516 90557906
Malignant neoplasm progression 28.27 14.83 3 33022 106867 90488555
Drug withdrawal syndrome 28.24 14.83 43 32982 28680 90566742
Wound infection 28.12 14.83 3 33022 106399 90489023
Miosis 27.93 14.83 25 33000 9459 90585963
Bipolar I disorder 27.58 14.83 14 33011 2068 90593354
Delirium 27.35 14.83 92 32933 104267 90491155
Conversion disorder 27.17 14.83 14 33011 2132 90593290
Mental disorder 27.12 14.83 45 32980 32273 90563149
Neonatal respiratory distress 27.10 14.83 10 33015 679 90594743
Urinary retention 27.03 14.83 49 32976 37695 90557727
Anger 26.99 14.83 29 32996 13691 90581731
Pleurothotonus 26.95 14.83 12 33013 1323 90594099
Electrocardiogram repolarisation abnormality 26.61 14.83 12 33013 1364 90594058
Renal cyst 26.58 14.83 28 32997 12922 90582500
Depressive symptom 26.42 14.83 19 33006 5266 90590156
Arthritis 26.41 14.83 14 33011 167301 90428121
Back pain 26.36 14.83 47 32978 317128 90278294
Electrocardiogram abnormal 26.17 14.83 25 33000 10273 90585149
Hypotonia neonatal 26.16 14.83 12 33013 1418 90594004
Stevens-Johnson syndrome 26.13 14.83 42 32983 29334 90566088
Hallucination, olfactory 25.85 14.83 8 33017 316 90595106
General physical health deterioration 25.75 14.83 57 32968 355058 90240364
Merycism 25.68 14.83 8 33017 323 90595099
Renal failure 25.55 14.83 105 32920 130902 90464520
Lipids decreased 25.43 14.83 4 33021 3 90595419
Staphylococcal abscess 25.43 14.83 10 33015 808 90594614
Thinking abnormal 25.22 14.83 26 32999 11706 90583716
Tonsillar hypertrophy 25.16 14.83 11 33014 1161 90594261
Chest pain 25.12 14.83 49 32976 319596 90275826
Dysphemia 25.06 14.83 15 33010 3055 90592367
Oral herpes 24.61 14.83 44 32981 33480 90561942
Nephropathy 24.58 14.83 23 33002 9212 90586210
Self-injurious ideation 24.47 14.83 15 33010 3188 90592234
Abdominal pain upper 24.45 14.83 53 32972 332621 90262801
Asterixis 24.29 14.83 12 33013 1673 90593749
Drooling 24.24 14.83 17 33008 4529 90590893
Renal impairment 24.23 14.83 89 32936 105332 90490090
Coordination abnormal 23.93 14.83 34 32991 21322 90574100
Hyperprolactinaemia 23.72 14.83 18 33007 5415 90590007
Irregular sleep wake rhythm disorder 23.71 14.83 7 33018 235 90595187
Anaemia 23.68 14.83 59 32966 352743 90242679
Blood creatinine increased 23.64 14.83 86 32939 101300 90494122
Enuresis 23.59 14.83 15 33010 3399 90592023
Histrionic personality disorder 23.51 14.83 5 33020 41 90595381
Urine osmolarity increased 23.33 14.83 6 33019 119 90595303
Hyperthyroidism 23.30 14.83 31 32994 18279 90577143
Balance disorder 23.19 14.83 83 32942 96997 90498425
Blood cholesterol increased 23.11 14.83 25 33000 207987 90387435
Cerebral atrophy 23.10 14.83 18 33007 5628 90589794
Night sweats 23.08 14.83 9 33016 128757 90466665
Adams-Stokes syndrome 22.99 14.83 5 33020 46 90595376
Borderline personality disorder 22.96 14.83 10 33015 1046 90594376
Visuospatial deficit 22.96 14.83 4 33021 9 90595413
Disinhibition 22.85 14.83 10 33015 1058 90594364
Clonus 22.81 14.83 18 33007 5732 90589690
Neutrophilia 22.73 14.83 18 33007 5760 90589662
Sluggishness 22.25 14.83 18 33007 5941 90589481
Generalised tonic-clonic seizure 22.11 14.83 43 32982 34860 90560562
Electric shock sensation 22.09 14.83 11 33014 1559 90593863
Poverty of speech 21.61 14.83 7 33018 321 90595101
Retroperitoneal fibrosis 21.28 14.83 7 33018 337 90595085
Congenital aqueductal stenosis 21.24 14.83 4 33021 16 90595406
Tachyphrenia 21.23 14.83 11 33014 1695 90593727
Nystagmus 21.18 14.83 19 33006 7208 90588214
Water intoxication 21.14 14.83 8 33017 583 90594839
Lower limb fracture 20.99 14.83 3 33022 85010 90510412
Tachycardia 20.93 14.83 113 32912 157560 90437862
Incoherent 20.65 14.83 16 33009 4961 90590461
Hypotonia 20.48 14.83 23 33002 11403 90584019
Differential white blood cell count abnormal 20.42 14.83 9 33016 969 90594453
Knee arthroplasty 20.38 14.83 3 33022 83179 90512243
Mood swings 20.36 14.83 31 32994 20671 90574751
Goitre 20.25 14.83 18 33007 6749 90588673
Red blood cell sedimentation rate increased 20.19 14.83 3 33022 82592 90512830
Hypercholesterolaemia 19.90 14.83 6 33019 100886 90494536
Muscle spasms 19.45 14.83 39 32986 251844 90343578
Weight increased 19.34 14.83 235 32790 417692 90177730
Breast engorgement 19.17 14.83 5 33020 105 90595317
Foetal malnutrition 19.17 14.83 5 33020 105 90595317
Brugada syndrome 19.07 14.83 7 33018 468 90594954
Sinus arrest 18.87 14.83 11 33014 2135 90593287
Drug ineffective 18.80 14.83 374 32651 1383924 89211498
Liver function test increased 18.75 14.83 4 33021 84851 90510571
Refusal of treatment by patient 18.65 14.83 16 33009 5722 90589700
Megacolon 18.55 14.83 11 33014 2203 90593219
Atrial fibrillation 18.54 14.83 13 33012 133598 90461824
Distal intestinal obstruction syndrome 18.42 14.83 7 33018 516 90594906
Camptocormia 18.28 14.83 6 33019 287 90595135
Increased appetite 18.27 14.83 22 33003 11743 90583679
Tubulointerstitial nephritis 18.27 14.83 33 32992 25310 90570112
Hypotension 18.23 14.83 190 32835 325207 90270215
Hip arthroplasty 18.10 14.83 3 33022 76205 90519217
Resting tremor 18.03 14.83 8 33017 875 90594547
Arachnoid cyst 17.89 14.83 6 33019 307 90595115
Electrocardiogram T wave inversion 17.86 14.83 13 33012 3670 90591752
Oscillopsia 17.80 14.83 5 33020 140 90595282
Therapeutic drug monitoring analysis not performed 17.79 14.83 9 33016 1320 90594102
Dyspepsia 17.71 14.83 28 32997 198132 90397290
Troponin increased 17.69 14.83 23 33002 13258 90582164
Parkinsonian gait 17.57 14.83 7 33018 585 90594837
Dehydration 17.43 14.83 126 32899 194321 90401101
Grip strength decreased 17.39 14.83 6 33019 92570 90502852
Radial nerve palsy 17.36 14.83 7 33018 604 90594818
Polyhydramnios 17.28 14.83 11 33014 2497 90592925
Oedema 17.25 14.83 29 32996 200266 90395156
Injection site reaction 17.24 14.83 6 33019 92074 90503348
Slow speech 17.24 14.83 10 33015 1923 90593499
Hypoxic-ischaemic encephalopathy 17.21 14.83 14 33011 4654 90590768
Meconium plug syndrome 17.21 14.83 4 33021 51 90595371
Hyperthermia 17.16 14.83 20 33005 10315 90585107
Inflammation 17.16 14.83 24 33001 178568 90416854
Eosinophil percentage increased 16.97 14.83 8 33017 1006 90594416
Adverse event 16.86 14.83 11 33014 117407 90478015
Muscle twitching 16.80 14.83 31 32994 24171 90571251
Electroconvulsive therapy 16.79 14.83 4 33021 57 90595365
Rapid eye movement sleep behaviour disorder 16.68 14.83 6 33019 379 90595043
Maternal exposure during pregnancy 16.66 14.83 71 32954 359992 90235430
Posture abnormal 16.50 14.83 11 33014 2700 90592722
Drug level above therapeutic 16.49 14.83 15 33010 5794 90589628
Colectomy total 16.44 14.83 5 33020 186 90595236
Amniotic fluid volume increased 16.32 14.83 5 33020 191 90595231
Erythrodermic psoriasis 16.31 14.83 8 33017 1098 90594324
Affective disorder 16.26 14.83 17 33008 7776 90587646
Seizure 16.12 14.83 103 32922 152526 90442896
Interstitial lung disease 16.09 14.83 4 33021 76401 90519021
Insomnia 16.07 14.83 189 32836 333285 90262137
Injection site pain 16.05 14.83 24 33001 173675 90421747
Alexithymia 16.03 14.83 4 33021 70 90595352
Schizoaffective disorder 16.02 14.83 14 33011 5133 90590289
Major depression 15.97 14.83 19 33006 10016 90585406
Tonic clonic movements 15.60 14.83 9 33016 1713 90593709
Electrocardiogram change 15.59 14.83 7 33018 787 90594635
Dry mouth 15.53 14.83 27 32998 184032 90411390
Crying 15.53 14.83 31 32994 25614 90569808
Thyrotoxic crisis 15.50 14.83 8 33017 1223 90594199
Hyperparathyroidism primary 15.49 14.83 6 33019 466 90594956
Amimia 15.48 14.83 4 33021 81 90595341
Urine output increased 15.41 14.83 9 33016 1753 90593669
Postural tremor 15.31 14.83 6 33019 480 90594942
Antidepressant drug level above therapeutic 15.27 14.83 6 33019 484 90594938
Cyclothymic disorder 15.20 14.83 5 33020 241 90595181
Nodal rhythm 15.14 14.83 9 33016 1809 90593613
Diabetes mellitus 15.10 14.83 55 32970 64820 90530602
Electrocardiogram QT interval abnormal 15.08 14.83 5 33020 247 90595175
Psoriasis 15.07 14.83 19 33006 147735 90447687
COVID-19 14.95 14.83 24 33001 168819 90426603
Disorganised speech 14.84 14.83 9 33016 1876 90593546

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Toxicity to various agents 624.27 15.65 703 23319 228433 42368880
Antipsychotic drug level increased 475.89 15.65 154 23868 4512 42592801
Antipsychotic drug level below therapeutic 402.55 15.65 124 23898 3080 42594233
Akathisia 384.64 15.65 163 23859 10288 42587025
Obsessive-compulsive disorder 351.13 15.65 135 23887 6608 42590705
Neuroleptic malignant syndrome 348.72 15.65 191 23831 21281 42576032
Disinhibition 346.67 15.65 116 23906 3779 42593534
Suicide attempt 345.32 15.65 251 23771 45849 42551464
Tremor 332.47 15.65 337 23685 96592 42500721
Therapeutic product effect variable 326.74 15.65 105 23917 3004 42594309
Euphoric mood 296.49 15.65 118 23904 6335 42590978
Increased appetite 266.19 15.65 120 23902 8786 42588527
Nephrogenic diabetes insipidus 263.24 15.65 76 23946 1498 42595815
Mania 228.91 15.65 114 23908 10433 42586880
Extrapyramidal disorder 217.85 15.65 128 23894 16284 42581029
Antipsychotic drug level above therapeutic 162.55 15.65 50 23972 1234 42596079
Sopor 134.50 15.65 87 23935 13115 42584198
Dysarthria 124.61 15.65 132 23890 39675 42557638
Leukaemia 124.07 15.65 62 23960 5710 42591603
Weight increased 122.81 15.65 219 23803 107764 42489549
Confusional state 115.08 15.65 276 23746 167321 42429992
Drug interaction 109.86 15.65 365 23657 266634 42330679
Hypomania 108.73 15.65 44 23978 2464 42594849
Agitation 106.76 15.65 155 23867 64159 42533154
Leukopenia 98.62 15.65 162 23860 74584 42522729
Diabetes insipidus 98.28 15.65 46 23976 3667 42593646
Psychotic disorder 97.02 15.65 100 23922 29108 42568205
Salivary hypersecretion 96.69 15.65 66 23956 10877 42586436
Dyslipidaemia 95.77 15.65 62 23960 9356 42587957
Irritability 92.88 15.65 96 23926 28032 42569281
Psychomotor hyperactivity 91.89 15.65 64 23958 10894 42586419
Parkinsonism 91.33 15.65 63 23959 10560 42586753
Serotonin syndrome 88.58 15.65 90 23932 25755 42571558
Ataxia 84.12 15.65 71 23951 16054 42581259
Therapeutic product effect incomplete 83.31 15.65 146 23876 70793 42526520
Febrile neutropenia 81.71 15.65 6 24016 185697 42411616
Aggression 81.50 15.65 112 23910 44051 42553262
Prescribed overdose 80.25 15.65 63 23959 12864 42584449
Schizoaffective disorder 80.06 15.65 33 23989 1937 42595376
Obesity 78.81 15.65 69 23953 16390 42580923
Poisoning deliberate 77.60 15.65 56 23966 10078 42587235
Suicidal ideation 75.46 15.65 113 23909 48048 42549265
Delusion 75.06 15.65 64 23958 14670 42582643
Coma 74.60 15.65 119 23903 53435 42543878
Dyspnoea 73.52 15.65 85 23937 442536 42154777
Bipolar disorder 72.32 15.65 38 23984 3884 42593429
Somnolence 70.89 15.65 207 23815 140898 42456415
White blood cell count increased 66.69 15.65 103 23919 44984 42552329
Hyperparathyroidism 64.01 15.65 25 23997 1274 42596039
Death 59.12 15.65 110 23912 471075 42126238
Arthralgia 59.03 15.65 21 24001 205217 42392096
Cough 58.96 15.65 14 24008 178089 42419224
Myoclonus 57.69 15.65 59 23963 17006 42580307
Sedation 57.28 15.65 78 23944 30397 42566916
Intentional overdose 56.66 15.65 103 23919 51353 42545960
Disease progression 52.30 15.65 9 24013 143647 42453666
Anaemia 51.86 15.65 49 23973 280229 42317084
Granulocytopenia 51.49 15.65 38 23984 7076 42590237
Hallucination, auditory 51.35 15.65 52 23970 14812 42582501
Dyskinesia 50.80 15.65 67 23955 25323 42571990
Catatonia 48.96 15.65 35 23987 6204 42591109
Intentional self-injury 48.58 15.65 51 23971 15151 42582162
Overdose 47.70 15.65 149 23873 105115 42492198
Fatigue 46.79 15.65 111 23911 435530 42161783
Schizophrenia 46.08 15.65 42 23980 10508 42586805
Mental status changes 45.97 15.65 84 23938 42031 42555282
Hypernatraemia 45.91 15.65 41 23981 9991 42587322
Tardive dyskinesia 45.70 15.65 35 23987 6889 42590424
Disorientation 45.44 15.65 77 23945 36312 42561001
Apraxia 43.69 15.65 20 24002 1515 42595798
Malignant neoplasm progression 43.65 15.65 5 24017 108395 42488918
Abnormal behaviour 42.75 15.65 63 23959 26388 42570925
Thinking abnormal 42.51 15.65 34 23988 7127 42590186
Disturbance in attention 42.44 15.65 67 23955 29799 42567514
Blood creatine phosphokinase increased 40.17 15.65 86 23936 48252 42549061
Atrial fibrillation 38.90 15.65 15 24007 139578 42457735
Patient restraint 37.96 15.65 9 24013 78 42597235
Dystonia 37.50 15.65 41 23981 12749 42584564
Dystonic tremor 37.07 15.65 12 24010 351 42596962
Back pain 36.68 15.65 17 24005 141759 42455554
Delirium 36.47 15.65 87 23935 52432 42544881
Muscle rigidity 35.96 15.65 39 23983 12020 42585293
Pancytopenia 35.66 15.65 11 24011 117732 42479581
Polydipsia 34.81 15.65 25 23997 4463 42592850
Cerebellar syndrome 34.56 15.65 21 24001 2834 42594479
Restlessness 34.04 15.65 60 23962 29189 42568124
Neutrophil count increased 33.21 15.65 48 23974 19756 42577557
Nephropathy 33.13 15.65 29 23993 6882 42590431
Abulia 33.01 15.65 13 24009 677 42596636
Kidney enlargement 32.92 15.65 14 24008 889 42596424
Electrocardiogram QT prolonged 32.83 15.65 79 23943 47866 42549447
Pneumonia 32.74 15.65 125 23897 422024 42175289
Floppy infant 32.69 15.65 9 24013 148 42597165
Pain 32.55 15.65 55 23967 244793 42352520
Off label use 32.48 15.65 219 23803 638116 41959197
Tachycardia foetal 32.26 15.65 11 24011 379 42596934
Protein S decreased 31.94 15.65 8 24014 89 42597224
Pain in extremity 31.93 15.65 23 23999 150581 42446732
Hyperparathyroidism primary 31.42 15.65 9 24013 172 42597141
Hyperthermia 31.25 15.65 37 23985 12537 42584776
General physical health deterioration 30.90 15.65 24 23998 151222 42446091
Brugada syndrome 30.85 15.65 14 24008 1039 42596274
Sexually inappropriate behaviour 30.73 15.65 12 24010 611 42596702
Otospondylomegaepiphyseal dysplasia 30.52 15.65 8 24014 108 42597205
Depressed level of consciousness 29.64 15.65 76 23946 47894 42549419
Bradyphrenia 29.16 15.65 24 23998 5238 42592075
Hypothyroidism 28.89 15.65 59 23963 32025 42565288
Apathy 28.29 15.65 29 23993 8377 42588936
Foetal exposure during pregnancy 28.24 15.65 74 23948 47237 42550076
Gastrointestinal haemorrhage 28.06 15.65 10 24012 97716 42499597
Treatment noncompliance 27.89 15.65 64 23958 37608 42559705
Logorrhoea 27.36 15.65 18 24004 2789 42594524
Completed suicide 27.12 15.65 117 23905 96348 42500965
Insomnia 26.33 15.65 134 23888 118119 42479194
Peripheral swelling 26.32 15.65 9 24013 90261 42507052
Foreign body aspiration 26.32 15.65 9 24013 313 42597000
Sepsis 26.27 15.65 45 23977 199289 42398024
Interstitial lung disease 26.27 15.65 6 24016 78456 42518857
Thrombocytopenia 25.96 15.65 42 23980 190237 42407076
Joint swelling 25.32 15.65 4 24018 68018 42529295
Enuresis 25.28 15.65 17 24005 2731 42594582
Blood sodium increased 25.13 15.65 18 24004 3200 42594113
Drug level above therapeutic 24.79 15.65 23 23999 5883 42591430
Infusion related reaction 23.98 15.65 3 24019 60803 42536510
Leukocytosis 23.70 15.65 52 23970 29656 42567657
Drug level increased 23.37 15.65 48 23974 26152 42571161
Hydrops foetalis 23.29 15.65 11 24011 894 42596419
Stupor 23.17 15.65 17 24005 3136 42594177
Blood prolactin increased 23.04 15.65 15 24007 2283 42595030
Blood thyroid stimulating hormone increased 22.98 15.65 21 24001 5271 42592042
Pruritus 22.75 15.65 45 23977 188726 42408587
Oedema peripheral 22.62 15.65 26 23996 136050 42461263
Respiratory disorder neonatal 22.60 15.65 14 24008 1956 42595357
Grandiosity 22.52 15.65 8 24014 312 42597001
Metabolic syndrome 22.51 15.65 14 24008 1969 42595344
Polyuria 22.51 15.65 28 23994 9983 42587330
Persistent depressive disorder 22.48 15.65 9 24013 490 42596823
Coordination abnormal 22.21 15.65 25 23997 8025 42589288
Hypothermia 21.96 15.65 31 23991 12484 42584829
Thrombosis 21.47 15.65 6 24016 68505 42528808
Electrocardiogram QRS complex prolonged 21.27 15.65 21 24001 5802 42591511
Thyroxine decreased 21.24 15.65 7 24015 217 42597096
Product dose omission issue 21.12 15.65 34 23988 154331 42442982
Anger 21.02 15.65 31 23991 12987 42584326
Wheezing 20.90 15.65 3 24019 54778 42542535
Hypotonia neonatal 20.80 15.65 12 24010 1472 42595841
Neurotoxicity 20.71 15.65 43 23979 23608 42573705
Depression 20.60 15.65 120 23902 111243 42486070
Treatment failure 20.54 15.65 5 24017 62619 42534694
Tri-iodothyronine decreased 20.07 15.65 6 24016 134 42597179
Speech disorder 19.94 15.65 48 23974 29073 42568240
Cognitive disorder 19.93 15.65 53 23969 34119 42563194
Intentional product use issue 19.54 15.65 8 24014 71825 42525488
Platelet count decreased 19.45 15.65 30 23992 138551 42458762
Diarrhoea 19.16 15.65 167 23855 460682 42136631
Hyperreflexia 19.05 15.65 16 24006 3591 42593722
Hyperleukocytosis 19.03 15.65 14 24008 2594 42594719
Anxiety 18.94 15.65 123 23899 118437 42478876
Tachycardia 18.74 15.65 109 23913 100978 42496335
Drooling 18.55 15.65 17 24005 4282 42593031
Hyperammonaemic encephalopathy 18.33 15.65 14 24008 2744 42594569
Injection site pain 18.22 15.65 5 24017 57793 42539520
Toxic encephalopathy 18.18 15.65 21 24001 6932 42590381
Hypokinesia 18.14 15.65 25 23997 9846 42587467
Arrhythmia supraventricular 18.12 15.65 11 24011 1482 42595831
Autoimmune hypothyroidism 18.11 15.65 6 24016 189 42597124
Pulmonary oedema 17.98 15.65 4 24018 53268 42544045
Priapism 17.85 15.65 20 24002 6387 42590926
Non-high-density lipoprotein cholesterol increased 17.79 15.65 6 24016 200 42597113
Left atrial dilatation 17.76 15.65 13 24009 2389 42594924
Weight 17.75 15.65 4 24018 27 42597286
Impulsive behaviour 17.65 15.65 13 24009 2412 42594901
Balance disorder 17.60 15.65 63 23959 47582 42549731
Albuminuria 17.57 15.65 8 24014 598 42596715
Drug abuse 17.53 15.65 110 23912 104661 42492652
Oncocytoma 17.37 15.65 3 24019 3 42597310
COVID-19 17.35 15.65 24 23998 115924 42481389
Cerebral calcification 17.06 15.65 5 24017 104 42597209
Major depression 17.05 15.65 18 24004 5380 42591933
Cardiac failure congestive 16.95 15.65 14 24008 85588 42511725
Sexual dysfunction 16.94 15.65 20 24002 6755 42590558
Psychiatric decompensation 16.87 15.65 16 24006 4206 42593107
Globulins increased 16.71 15.65 7 24015 428 42596885
Self esteem inflated 16.51 15.65 3 24019 5 42597308
Myocardial infarction 16.32 15.65 28 23994 123981 42473332
Distractibility 16.30 15.65 7 24015 455 42596858
Cogwheel rigidity 16.23 15.65 11 24011 1790 42595523
Cardiac failure 16.10 15.65 22 24000 106834 42490479
Agitation neonatal 16.00 15.65 10 24012 1418 42595895
Dysphagia 15.89 15.65 82 23940 72637 42524676
Self-injurious ideation 15.87 15.65 11 24011 1857 42595456
Pneumonia aspiration 15.84 15.65 63 23959 50015 42547298
Septic shock 15.80 15.65 17 24005 91655 42505658
Aphasia 15.75 15.65 39 23983 24044 42573269

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Toxicity to various agents 1413.40 14.38 1364 46909 479191 110061835
Antipsychotic drug level increased 1162.55 14.38 318 47955 6697 110534329
Tremor 969.15 14.38 760 47513 201472 110339554
Neuroleptic malignant syndrome 702.68 14.38 328 47945 33731 110507295
Extrapyramidal disorder 648.63 14.38 295 47978 28572 110512454
Drug interaction 554.13 14.38 869 47404 499314 110041712
Sopor 541.80 14.38 281 47992 36265 110504761
Nephrogenic diabetes insipidus 539.11 14.38 139 48134 2306 110538720
Antipsychotic drug level above therapeutic 495.82 14.38 130 48143 2310 110538716
Mania 409.47 14.38 194 48079 20602 110520424
Agitation 341.53 14.38 327 47946 112724 110428302
Dysarthria 336.38 14.38 285 47988 83836 110457190
Confusional state 334.06 14.38 672 47601 468008 110073018
Suicide attempt 333.22 14.38 310 47963 103084 110437942
Drug abuse 330.37 14.38 397 47876 177014 110364012
Coma 302.50 14.38 312 47961 117557 110423469
Akathisia 292.71 14.38 145 48128 16968 110524058
Somnolence 286.64 14.38 486 47787 296963 110244063
Parkinsonism 273.65 14.38 151 48122 22036 110518990
Ataxia 268.39 14.38 166 48107 29942 110511084
Intentional self-injury 261.34 14.38 177 48096 37252 110503774
Serotonin syndrome 233.52 14.38 199 48074 58954 110482072
Hyperparathyroidism 223.87 14.38 78 48195 3732 110537294
Salivary hypersecretion 216.03 14.38 119 48154 17302 110523724
Overdose 201.65 14.38 364 47909 233430 110307596
Suicidal ideation 201.11 14.38 226 48047 93711 110447315
Antipsychotic drug level below therapeutic 198.77 14.38 59 48214 1676 110539350
Poisoning deliberate 184.94 14.38 125 48148 26206 110514820
Diabetes insipidus 175.99 14.38 76 48197 6494 110534532
Hallucination, auditory 172.83 14.38 120 48153 26277 110514749
Intentional overdose 171.25 14.38 248 48025 132253 110408773
Delusion 167.38 14.38 113 48160 23642 110517384
Tardive dyskinesia 166.29 14.38 92 48181 13487 110527539
Aggression 165.07 14.38 164 48109 59046 110481980
Sedation 160.10 14.38 174 48099 69509 110471517
Dyspnoea 160.04 14.38 149 48124 1106723 109434303
Disorientation 159.81 14.38 175 48098 70496 110470530
Bradyphrenia 159.00 14.38 85 48188 11643 110529383
Altered state of consciousness 157.67 14.38 158 48115 57468 110483558
Psychotic disorder 156.85 14.38 149 48124 50788 110490238
Muscle rigidity 156.75 14.38 109 48164 23922 110517104
Hypomania 155.53 14.38 80 48193 10130 110530896
Polyuria 151.00 14.38 95 48178 17643 110523383
Disturbance in attention 149.80 14.38 159 48114 61836 110479190
Cerebellar syndrome 149.71 14.38 67 48206 6235 110534791
Pain 149.59 14.38 119 48154 954836 109586190
Hypernatraemia 145.55 14.38 93 48180 17740 110523286
Psychomotor hyperactivity 141.78 14.38 96 48177 20181 110520845
Infusion related reaction 140.71 14.38 6 48267 381156 110159870
Arthralgia 138.08 14.38 85 48188 779547 109761479
Disinhibition 131.33 14.38 50 48223 3084 110537942
Euphoric mood 131.10 14.38 68 48205 8759 110532267
Myoclonus 128.13 14.38 110 48163 32888 110508138
Obsessive-compulsive disorder 125.73 14.38 62 48211 7179 110533847
Encephalopathy 123.08 14.38 164 48109 80891 110460135
Dyskinesia 122.61 14.38 131 48142 51315 110489711
Drug level increased 119.93 14.38 125 48148 47594 110493432
Irritability 119.74 14.38 125 48148 47684 110493342
Depressed level of consciousness 119.39 14.38 192 48081 112086 110428940
Electrocardiogram QT prolonged 116.78 14.38 187 48086 108773 110432253
Body tinea 115.47 14.38 41 48232 2074 110538952
Joint swelling 115.44 14.38 26 48247 442819 110098207
Schizophrenia 110.61 14.38 85 48188 21741 110519285
Acute kidney injury 110.24 14.38 558 47715 634872 109906154
Bipolar disorder 110.22 14.38 61 48212 8946 110532080
Completed suicide 108.57 14.38 290 47983 242091 110298935
Restlessness 106.35 14.38 127 48146 56132 110484894
Schizoaffective disorder 103.18 14.38 42 48231 3094 110537932
Systemic lupus erythematosus 97.31 14.38 3 48270 254335 110286691
Swelling 96.87 14.38 18 48255 351023 110190003
Polydipsia 96.64 14.38 53 48220 7635 110533391
Mental status changes 96.15 14.38 141 48132 75981 110465045
Speech disorder 95.66 14.38 126 48147 61443 110479583
Catatonia 94.87 14.38 60 48213 11240 110529786
Hyperreflexia 94.03 14.38 56 48217 9429 110531597
Increased appetite 93.17 14.38 66 48207 14911 110526115
Rheumatoid arthritis 92.70 14.38 11 48262 299602 110241424
Inhibitory drug interaction 90.81 14.38 44 48229 4903 110536123
Febrile neutropenia 90.11 14.38 15 48258 316752 110224274
Hypersensitivity 89.95 14.38 32 48241 403966 110137060
Blood creatine phosphokinase increased 88.90 14.38 133 48140 72944 110468082
Treatment failure 88.76 14.38 9 48264 277225 110263801
Therapeutic product effect variable 88.05 14.38 36 48237 2682 110538344
Hypothyroidism 87.72 14.38 132 48141 72767 110468259
Abnormal behaviour 87.06 14.38 96 48177 38943 110502083
Glucose tolerance impaired 87.04 14.38 54 48219 9783 110531243
Infection susceptibility increased 86.45 14.38 41 48232 4357 110536669
Cough 86.34 14.38 47 48226 461594 110079432
Dystonia 86.19 14.38 79 48194 25726 110515300
Drug intolerance 85.84 14.38 35 48238 406477 110134549
White blood cell count increased 83.64 14.38 151 48122 96691 110444335
Arthropathy 83.16 14.38 13 48260 287509 110253517
Alopecia 82.73 14.38 28 48245 364725 110176301
Pericarditis 82.35 14.38 3 48270 219111 110321915
Electroencephalogram abnormal 81.60 14.38 44 48229 6129 110534897
Granulocytopenia 81.34 14.38 57 48216 12658 110528368
Urticaria 80.53 14.38 20 48253 318837 110222189
Bradykinesia 80.04 14.38 53 48220 10735 110530291
Sinusitis 78.12 14.38 17 48256 296671 110244355
Pruritus 77.26 14.38 84 48189 581476 109959550
Abdominal discomfort 76.75 14.38 38 48235 393820 110147206
Wound 76.65 14.38 7 48266 234430 110306596
Neurotoxicity 74.43 14.38 92 48181 42115 110498911
Glossodynia 74.30 14.38 6 48267 221998 110319028
Peripheral swelling 74.29 14.38 42 48231 403992 110137034
Nasopharyngitis 72.50 14.38 41 48232 394320 110146706
Logorrhoea 70.22 14.38 37 48236 4920 110536106
Delirium 70.21 14.38 171 48102 134854 110406172
Psoriatic arthropathy 69.69 14.38 4 48269 196757 110344269
Stomatitis 68.14 14.38 17 48256 270225 110270801
Hypercalcaemia 67.15 14.38 92 48181 46565 110494461
Impaired healing 66.72 14.38 5 48268 196712 110344314
Blister 66.38 14.38 10 48263 227366 110313660
Contraindicated product administered 65.81 14.38 14 48259 248253 110292773
Hypokinesia 65.56 14.38 63 48210 21763 110519263
Hyperparathyroidism primary 65.03 14.38 19 48254 510 110540516
Aphasia 64.21 14.38 102 48171 58895 110482131
Neutrophil count increased 63.48 14.38 77 48196 34575 110506451
Off label use 63.46 14.38 390 47883 1499795 109041231
Nephropathy 62.94 14.38 50 48223 13417 110527609
Disease progression 62.21 14.38 15 48258 244019 110297007
Sinus bradycardia 61.46 14.38 70 48203 29413 110511613
Wheezing 60.69 14.38 18 48255 255212 110285814
Malignant neoplasm progression 60.47 14.38 4 48269 174563 110366463
Pyramidal tract syndrome 60.19 14.38 20 48253 827 110540199
Cogwheel rigidity 59.29 14.38 30 48243 3668 110537358
Cognitive disorder 59.11 14.38 123 48150 87388 110453638
Pneumonia 58.64 14.38 192 48081 876522 109664504
Leukocytosis 58.49 14.38 93 48180 53735 110487291
Pain in extremity 57.61 14.38 77 48196 487041 110053985
Treatment noncompliance 56.99 14.38 109 48164 72881 110468145
Drug hypersensitivity 56.58 14.38 69 48204 454021 110087005
Gait disturbance 56.54 14.38 256 48017 277952 110263074
Anaemia 56.45 14.38 95 48178 546991 109994035
Persistent depressive disorder 56.31 14.38 22 48251 1455 110539571
Lower respiratory tract infection 56.26 14.38 18 48255 243088 110297938
Fibromyalgia 56.14 14.38 5 48268 170904 110370122
Fatigue 55.12 14.38 309 47964 1215649 109325377
Intentional product use issue 54.53 14.38 20 48253 247886 110293140
Hyperthermia 53.94 14.38 56 48217 21216 110519810
Poisoning 53.84 14.38 65 48208 29040 110511986
Thinking abnormal 53.80 14.38 48 48225 15092 110525934
Death 53.23 14.38 144 48129 698725 109842301
Apathy 52.84 14.38 49 48224 16190 110524836
Poor quality sleep 52.42 14.38 63 48210 28014 110513012
Hypothermia 52.39 14.38 61 48212 26241 110514785
Psychomotor retardation 52.35 14.38 36 48237 7756 110533270
Back pain 52.14 14.38 51 48222 370945 110170081
Gestational diabetes 51.69 14.38 35 48238 7354 110533672
Brugada syndrome 51.33 14.38 21 48252 1567 110539459
Haemodialysis 51.07 14.38 50 48223 17669 110523357
Psychomotor skills impaired 50.73 14.38 34 48239 7024 110534002
Faecaloma 50.49 14.38 46 48227 14862 110526164
Therapeutic product effect decreased 49.99 14.38 22 48251 244294 110296732
Arthritis 49.77 14.38 7 48266 167579 110373447
Asthma 48.95 14.38 24 48249 250267 110290759
Apraxia 48.95 14.38 26 48247 3514 110537512
Leukopenia 48.40 14.38 159 48114 148632 110392394
Stupor 48.15 14.38 35 48238 8230 110532796
Enuresis 48.09 14.38 27 48246 4069 110536957
Hypoaesthesia 47.97 14.38 40 48233 314183 110226843
Behaviour disorder 47.63 14.38 37 48236 9610 110531416
Mobility decreased 47.61 14.38 22 48251 237400 110303626
Cardio-respiratory arrest 47.23 14.38 134 48139 115702 110425324
Psychiatric decompensation 46.88 14.38 30 48243 5735 110535291
Chronic kidney disease 46.65 14.38 103 48170 76188 110464838
Atrial fibrillation 46.48 14.38 21 48252 229621 110311405
Depressed mood 46.48 14.38 90 48183 60719 110480307
Infection 46.21 14.38 54 48219 362146 110178880
Irritable bowel syndrome 46.18 14.38 8 48265 164207 110376819
Dyslipidaemia 45.92 14.38 45 48228 15920 110525106
Toxic encephalopathy 45.86 14.38 44 48229 15170 110525856
Rash 45.59 14.38 194 48079 820770 109720256
Blood sodium increased 45.55 14.38 29 48244 5494 110535532
Musculoskeletal pain 45.19 14.38 12 48261 183011 110358015
Headache 45.11 14.38 215 48058 882162 109658864
General physical health deterioration 44.64 14.38 73 48200 425222 110115804
Dystonic tremor 43.97 14.38 13 48260 364 110540662
Drooling 43.34 14.38 31 48242 7108 110533918
Coordination abnormal 42.89 14.38 54 48219 25174 110515852
Protein C increased 42.73 14.38 9 48264 57 110540969
Impaired work ability 42.47 14.38 55 48218 26364 110514662
Bone density decreased 42.06 14.38 43 48230 15999 110525027
Language disorder 41.57 14.38 24 48249 3814 110537212
Otospondylomegaepiphyseal dysplasia 41.45 14.38 8 48265 30 110540996
Parathyroid tumour benign 41.08 14.38 16 48257 1049 110539977
Hypertonia 40.98 14.38 32 48241 8374 110532652
Lethargy 40.87 14.38 111 48162 93465 110447561
Liver injury 40.85 14.38 8 48265 150405 110390621
Mutism 40.62 14.38 22 48251 3091 110537935
Product use issue 40.26 14.38 46 48227 311649 110229377
Urinary incontinence 39.71 14.38 74 48199 48513 110492513
Osteoarthritis 39.70 14.38 15 48258 182608 110358418
Hepatic enzyme increased 39.69 14.38 49 48224 320843 110220183
Bursitis 39.60 14.38 5 48268 129913 110411113
Abdominal pain upper 39.43 14.38 57 48216 349054 110191972
Ill-defined disorder 39.27 14.38 10 48263 156843 110384183
Balance disorder 39.20 14.38 126 48147 116434 110424592
Blood urea increased 39.18 14.38 79 48194 54878 110486148
Hallucination 39.10 14.38 115 48158 101317 110439709
Self-injurious ideation 38.81 14.38 24 48249 4322 110536704
Depressive symptom 38.81 14.38 31 48242 8383 110532643
Patient restraint 38.65 14.38 9 48264 95 110540931
Clonus 37.84 14.38 31 48242 8685 110532341
Drug level above therapeutic 37.77 14.38 35 48238 11553 110529473
Anger 37.72 14.38 44 48229 18963 110522063
Renal cyst 37.63 14.38 43 48230 18129 110522897
Lung disorder 37.17 14.38 16 48257 180031 110360995
Interstitial lung disease 36.62 14.38 8 48265 139326 110401700
Tachycardia 36.35 14.38 195 48078 226450 110314576
Hyperlipidaemia 36.31 14.38 60 48213 35788 110505238
Pneumonia aspiration 36.11 14.38 97 48176 81136 110459890
Discomfort 35.73 14.38 25 48248 214682 110326344
Paraesthesia 35.50 14.38 41 48232 276480 110264546
Persecutory delusion 35.20 14.38 26 48247 6265 110534761
Bipolar I disorder 35.09 14.38 18 48255 2265 110538761
Status epilepticus 34.92 14.38 55 48218 31516 110509510
Blood prolactin increased 34.91 14.38 23 48250 4619 110536407
Induced abortion failed 34.63 14.38 9 48264 154 110540872
Depression 34.50 14.38 247 48026 317088 110223938
Major depression 34.46 14.38 32 48241 10589 110530437
Anxiety 34.34 14.38 263 48010 344815 110196211
Sinus arrest 34.31 14.38 22 48251 4220 110536806
Gastrointestinal disorder 34.28 14.38 33 48240 241919 110299107
Bundle branch block right 34.15 14.38 34 48239 12257 110528769
Blood creatinine increased 33.98 14.38 164 48109 182725 110358301
Bradycardia 33.76 14.38 146 48127 155371 110385655
Dialysis 33.36 14.38 42 48231 19577 110521449
Rhabdomyolysis 33.35 14.38 122 48151 120279 110420747
Hyperleukocytosis 33.30 14.38 20 48253 3419 110537607
Insomnia 33.23 14.38 270 48003 360320 110180706
Sexually inappropriate behaviour 32.85 14.38 12 48261 659 110540367
Pancytopenia 32.83 14.38 26 48247 209587 110331439
International normalised ratio abnormal 32.74 14.38 25 48248 6332 110534694
Miosis 32.61 14.38 44 48229 21939 110519087
Withdrawal syndrome 32.43 14.38 53 48220 31327 110509699
Psychiatric symptom 32.32 14.38 29 48244 9184 110531842
Gastrointestinal haemorrhage 32.16 14.38 16 48257 165502 110375524
Chest pain 32.16 14.38 73 48200 376302 110164724
Purpura 31.98 14.38 46 48227 24342 110516684
Abulia 31.32 14.38 14 48259 1299 110539727
Hyperthyroidism 31.02 14.38 50 48223 29211 110511815
Grandiosity 30.76 14.38 11 48262 568 110540458
Injection site pain 30.57 14.38 20 48253 177902 110363124
Dysphemia 30.35 14.38 20 48253 4017 110537009
Generalised tonic-clonic seizure 30.29 14.38 71 48202 54609 110486417
Cardiac failure congestive 30.25 14.38 14 48259 150986 110390040
Adams-Stokes syndrome 30.25 14.38 8 48265 147 110540879
Impaired quality of life 30.08 14.38 50 48223 29967 110511059
Protein S decreased 30.05 14.38 8 48265 151 110540875
Sepsis 30.04 14.38 61 48212 327285 110213741
Ileus paralytic 29.94 14.38 31 48242 11706 110529320
Muscle spasms 29.87 14.38 47 48226 278110 110262916
Sciatica 29.55 14.38 3 48270 92396 110448630
Weight increased 29.36 14.38 296 47977 419348 110121678
Paranoia 29.04 14.38 42 48231 22332 110518694
Inflammation 28.98 14.38 25 48248 193213 110347813
Myocarditis septic 28.76 14.38 6 48267 36 110540990
Wound infection 28.71 14.38 4 48269 96461 110444565
COVID-19 28.67 14.38 39 48234 245021 110296005
Mucosal inflammation 28.58 14.38 4 48269 96137 110444889
Electroconvulsive therapy 28.38 14.38 7 48266 96 110540930
Neuropathy peripheral 28.37 14.38 22 48251 179255 110361771
Choreoathetosis 27.88 14.38 14 48259 1684 110539342
Foreign body aspiration 27.81 14.38 10 48263 525 110540501
Mental impairment 27.23 14.38 41 48232 22598 110518428
Electrocardiogram T wave abnormal 27.20 14.38 19 48254 4198 110536828
Asterixis 27.09 14.38 17 48256 3141 110537885
Abdominal pain 26.74 14.38 124 48149 512865 110028161
Differential white blood cell count abnormal 26.67 14.38 15 48258 2269 110538757
Deprescribing error 26.34 14.38 6 48267 57 110540969
Impulsive behaviour 26.33 14.38 17 48256 3298 110537728
Encopresis 26.30 14.38 7 48266 132 110540894
Conversion disorder 26.15 14.38 15 48258 2355 110538671
Dehydration 26.12 14.38 210 48063 279301 110261725
Distractibility 26.04 14.38 11 48262 890 110540136
Night sweats 25.96 14.38 13 48260 133970 110407056
Hyperprolactinaemia 25.68 14.38 22 48251 6553 110534473
Myelosuppression 25.65 14.38 5 48268 94335 110446691
Oncocytoma 25.65 14.38 5 48268 20 110541006
Myasthenic syndrome 25.40 14.38 12 48261 1264 110539762
Galactorrhoea 25.13 14.38 18 48255 4137 110536889
Hyporeflexia 25.11 14.38 18 48255 4142 110536884
Sluggishness 24.94 14.38 23 48250 7544 110533482
Reflexes abnormal 24.45 14.38 11 48262 1036 110539990
Electrocardiogram T wave inversion 24.24 14.38 20 48253 5660 110535366
Neutrophilia 24.07 14.38 26 48247 10303 110530723
Influenza 24.02 14.38 23 48250 169078 110371948
Visuospatial deficit 23.83 14.38 5 48268 31 110540995
Agranulocytosis 23.77 14.38 70 48203 61690 110479336
Merycism 23.71 14.38 8 48265 347 110540679
Injection site reaction 23.64 14.38 5 48268 89065 110451961
Thrombocytopenia 23.53 14.38 76 48197 348809 110192217
Nodal rhythm 23.43 14.38 16 48257 3407 110537619
Nystagmus 23.30 14.38 27 48246 11550 110529476
Irregular sleep wake rhythm disorder 23.20 14.38 8 48265 371 110540655
Urinary retention 23.12 14.38 75 48198 69608 110471418
Poverty of speech 23.08 14.38 9 48264 592 110540434
Rhinorrhoea 23.04 14.38 8 48265 102658 110438368
Progressive supranuclear palsy 23.00 14.38 7 48266 217 110540809
Diarrhoea 22.88 14.38 355 47918 1139150 109401876
Dyspepsia 22.73 14.38 30 48243 190935 110350091
Lower limb fracture 22.72 14.38 3 48270 75345 110465681
Electrocardiogram abnormal 22.67 14.38 34 48239 18675 110522351
Fluid intake reduced 22.57 14.38 21 48252 6965 110534061
Mental disorder 22.18 14.38 51 48222 38740 110502286
Water intoxication 22.15 14.38 10 48263 949 110540077
Restless legs syndrome 22.02 14.38 39 48234 24587 110516439
Blood thyroid stimulating hormone increased 21.98 14.38 27 48246 12274 110528752
Metabolic syndrome 21.81 14.38 15 48258 3232 110537794
Cardiac failure 21.80 14.38 30 48243 187596 110353430
Hallucination, visual 21.47 14.38 51 48222 39554 110501472
Maternal exposure during pregnancy 21.31 14.38 50 48223 254833 110286193
Colitis ulcerative 21.25 14.38 4 48269 77359 110463667
Rectal haemorrhage 21.23 14.38 13 48260 119820 110421206
Dysphagia 21.21 14.38 127 48146 153473 110387553
Incoherent 21.18 14.38 22 48251 8336 110532690
Acquired cystic kidney disease 21.04 14.38 5 48268 58 110540968
Electrocardiogram QRS complex prolonged 20.76 14.38 27 48246 12994 110528032
Gastrooesophageal reflux disease 20.69 14.38 29 48244 179947 110361079
Hypercholesterolaemia 20.52 14.38 7 48266 90830 110450196
Kidney enlargement 20.35 14.38 11 48262 1540 110539486
Pleurothotonus 20.31 14.38 13 48260 2485 110538541
Blood pressure fluctuation 20.27 14.38 4 48269 74820 110466206
Platelet count decreased 20.24 14.38 44 48229 230399 110310627
Melaena 20.11 14.38 3 48270 68754 110472272
Injection site erythema 20.03 14.38 8 48265 94168 110446858
Impaired self-care 20.00 14.38 13 48260 2551 110538475
Hallucination, olfactory 19.69 14.38 8 48265 586 110540440
Upper respiratory tract infection 19.68 14.38 17 48256 131311 110409715
Malaise 19.62 14.38 193 48080 671626 109869400
Drug withdrawal syndrome 19.56 14.38 48 48225 38006 110503020
Anaphylactic reaction 19.42 14.38 13 48260 114287 110426739
Bronchitis 19.38 14.38 24 48249 157008 110384018
Feeling guilty 19.15 14.38 9 48264 937 110540089
Adverse event 19 14.38 12 48261 108797 110432229
Pneumonitis 18.92 14.38 5 48268 76526 110464500
Nausea 18.82 14.38 404 47869 1235286 109305740
Condition aggravated 18.68 14.38 218 48055 734618 109806408
Knee arthroplasty 18.62 14.38 3 48270 64945 110476081
Electrocardiogram repolarisation abnormality 18.61 14.38 12 48261 2323 110538703
Haematochezia 18.50 14.38 14 48259 115510 110425516
Left atrial dilatation 18.33 14.38 14 48259 3546 110537480
Haemorrhage 18.31 14.38 12 48261 106680 110434346
Alexithymia 18.29 14.38 4 48269 31 110540995
Productive cough 18.12 14.38 14 48259 114291 110426735
Hypersexuality 18.05 14.38 11 48262 1929 110539097
Electric shock sensation 18.03 14.38 11 48262 1933 110539093
Mood altered 18.02 14.38 33 48240 21342 110519684
Ascites 17.98 14.38 9 48264 92799 110448227
Cerebral atrophy 17.97 14.38 21 48252 9064 110531962
Seizure 17.92 14.38 161 48112 221024 110320002
Alcohol interaction 17.87 14.38 14 48259 3680 110537346
Muscle twitching 17.83 14.38 40 48233 29895 110511131
Renal impairment 17.82 14.38 142 48131 188303 110352723
Respiratory arrest 17.79 14.38 61 48212 58238 110482788
Borderline personality disorder 17.77 14.38 9 48264 1103 110539923
Ear infection 17.76 14.38 3 48270 62729 110478297
Drug reaction with eosinophilia and systemic symptoms 17.75 14.38 77 48196 82018 110459008
Radial nerve palsy 17.69 14.38 7 48266 479 110540547
Leukaemia 17.65 14.38 19 48254 7499 110533527
Tubulointerstitial nephritis 17.63 14.38 58 48215 54226 110486800
Histrionic personality disorder 17.56 14.38 4 48269 38 110540988
Hepatic cirrhosis 17.53 14.38 4 48269 67622 110473404
Migraine 17.49 14.38 30 48243 171622 110369404
International normalised ratio increased 17.45 14.38 8 48265 86764 110454262
Injection site swelling 17.39 14.38 3 48270 61787 110479239
Weight 17.29 14.38 4 48269 41 110540985
Urine osmolarity increased 17.08 14.38 6 48267 294 110540732
Frequent bowel movements 17.02 14.38 5 48268 71385 110469641
Blood osmolarity increased 17.02 14.38 8 48265 833 110540193
Goitre 16.94 14.38 17 48256 6187 110534839
Blood pressure increased 16.92 14.38 57 48216 258316 110282710
Grip strength decreased 16.74 14.38 7 48266 80167 110460859
Intention tremor 16.55 14.38 8 48265 886 110540140
Acute myocardial infarction 16.42 14.38 8 48265 83769 110457257
Neoplasm progression 16.39 14.38 4 48269 64591 110476435
Feelings of worthlessness 16.38 14.38 7 48266 583 110540443
Neutrophil percentage increased 16.32 14.38 15 48258 4898 110536128
Pressure of speech 16.24 14.38 9 48264 1323 110539703
Oedema 16.14 14.38 43 48230 209933 110331093
Bruxism 16.11 14.38 15 48258 4979 110536047
Antidepressant drug level increased 16.09 14.38 7 48266 609 110540417
Weight decreased 16.05 14.38 129 48144 467928 110073098
Atrioventricular block first degree 16.03 14.38 25 48248 14200 110526826
Oral herpes 15.95 14.38 43 48230 36037 110504989
Breast engorgement 15.95 14.38 4 48269 59 110540967
Skin disorder 15.91 14.38 48 48225 42865 110498161
Priapism 15.89 14.38 16 48257 5845 110535181
Job change 15.82 14.38 3 48270 10 110541016
Myocardial infarction 15.80 14.38 38 48235 192045 110348981
Antipsychotic drug level decreased 15.75 14.38 9 48264 1403 110539623
Arrhythmia supraventricular 15.73 14.38 11 48262 2435 110538591
Fluid retention 15.66 14.38 11 48262 94296 110446730
Psoriasis 15.65 14.38 23 48250 139970 110401056
Posture abnormal 15.63 14.38 14 48259 4424 110536602
Albuminuria 15.62 14.38 8 48265 1003 110540023
Distal intestinal obstruction syndrome 15.52 14.38 8 48265 1017 110540009
Antipsychotic drug level 15.39 14.38 3 48270 12 110541014
Respiratory disorder 15.28 14.38 6 48267 71376 110469650
Haemoptysis 15.27 14.38 6 48267 71348 110469678
Lactic acidosis 15.18 14.38 11 48262 92800 110448226
Hyperthermia malignant 15.13 14.38 13 48260 3887 110537139
Compulsions 15.11 14.38 6 48267 414 110540612
Abdominal distension 14.91 14.38 34 48239 175069 110365957
Cardiomyopathy 14.86 14.38 40 48233 33485 110507541
Lipids decreased 14.84 14.38 3 48270 15 110541011
Mydriasis 14.79 14.38 31 48242 22126 110518900
Arachnoid cyst 14.71 14.38 6 48267 444 110540582
Antidepressant drug level above therapeutic 14.70 14.38 7 48266 750 110540276
Poriomania 14.68 14.38 5 48268 223 110540803
Retroperitoneal fibrosis 14.68 14.38 7 48266 753 110540273
Loss of personal independence in daily activities 14.58 14.38 27 48246 149993 110391033
Amimia 14.58 14.38 4 48269 85 110540941
Sinus arrhythmia 14.52 14.38 10 48263 2160 110538866

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05AN01 NERVOUS SYSTEM
PSYCHOLEPTICS
ANTIPSYCHOTICS
Lithium
CHEBI has role CHEBI:35469 antidepressant
CHEBI has role CHEBI:35474 anxiolytic drug
CHEBI has role CHEBI:35476 antipsychotic agent
CHEBI has role CHEBI:35477 antimanic drug
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:35705 immunosuppressive agent
CHEBI has role CHEBI:48407 antiparkinson drug
CHEBI has role CHEBI:149553 anticoronaviral agent
MeSH PA D000928 Antidepressive Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D011619 Psychotropic Drugs
MeSH PA D018692 Antimanic Agents

Related Drugs by ATC class:

N05AN Lithium 1 drug
lithium citrate

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Bipolar disorder indication 13746004 DOID:3312
Pain indication 22253000
Rheumatoid arthritis indication 69896004 DOID:7148
Bipolar disorder in remission indication 85248005
Bipolar affective disorder, current episode manic indication 191618007
Headache disorder indication 230461009
Dysmenorrhea indication 266599000
Fever indication 386661006
Osteoarthritis indication 396275006
Juvenile rheumatoid arthritis indication 410795001
Vascular headache off-label use 128187005
Bipolar affective disorder, current episode depression off-label use 191627008 DOID:3312
Cluster Headache Prevention off-label use
Rapid Cycling Bipolar Affective Disorder off-label use
Psoriasis contraindication 9014002 DOID:8893
Diabetes insipidus contraindication 15771004 DOID:9409
Polyuria contraindication 28442001
Hypothyroidism contraindication 40930008 DOID:1459
Conduction disorder of the heart contraindication 44808001
Chronic heart failure contraindication 48447003
Acute infectious disease contraindication 63171007
Hyponatremia contraindication 89627008
Kidney disease contraindication 90708001 DOID:557
Organic mental disorder contraindication 111479008
Plaque psoriasis contraindication 200965009
Pregnancy, function contraindication 289908002
Breastfeeding (mother) contraindication 413712001
Severe dehydration contraindication 450316000
Lithium Toxicity contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Glycogen synthase kinase-3 Kinase INHIBITOR CHEMBL CHEMBL
Inositol-1(or 4)-monophosphatase 1 Enzyme INHIBITOR CHEMBL CHEMBL

External reference:

IDSource
4018007 VUID
N0000146351 NUI
D00801 KEGG_DRUG
4018007 VANDF
4019803 VANDF
C0085217 UMLSCUI
CHEBI:6504 CHEBI
CHEMBL1200826 ChEMBL_ID
D016651 MESH_DESCRIPTOR_UI
DB14509 DRUGBANK_ID
2BMD2GNA4V UNII
11125 PUBCHEM_CID
42351 RXNORM
1990 MMSL
4986 MMSL
d00061 MMSL
001532 NDDF
001533 NDDF
16977003 SNOMEDCT_US
321719003 SNOMEDCT_US
387095003 SNOMEDCT_US
85899009 SNOMEDCT_US
C0023870 UMLSCUI
CHEMBL1201333 ChEMBL_ID
7439-93-2 SECONDARY_CAS_RN
3028194 PUBCHEM_CID
D008094 MESH_DESCRIPTOR_UI
9FN79X2M3F UNII
CHEBI:30145 CHEBI
2BMD2GNA4V INXIGHT DRUGS
9FN79X2M3F INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-0020 TABLET, EXTENDED RELEASE 450 mg ORAL ANDA 16 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-0021 TABLET, EXTENDED RELEASE 300 mg ORAL ANDA 13 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-2526 CAPSULE, GELATIN COATED 150 mg ORAL NDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-2527 CAPSULE, GELATIN COATED 300 mg ORAL NDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-2531 CAPSULE, GELATIN COATED 600 mg ORAL NDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-4527 TABLET 300 mg ORAL NDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-8526 CAPSULE, GELATIN COATED 150 mg ORAL NDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-8527 CAPSULE, GELATIN COATED 300 mg ORAL NDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-8528 TABLET 300 mg ORAL NDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0054-8531 CAPSULE, GELATIN COATED 600 mg ORAL NDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 0615-8480 CAPSULE 300 mg ORAL ANDA 26 sections
LITHIUM CARBONATE HUMAN PRESCRIPTION DRUG LABEL 1 16590-781 TABLET 300 mg ORAL NDA 2 sections
Lithium carbonate HUMAN PRESCRIPTION DRUG LABEL 1 23155-763 TABLET, FILM COATED, EXTENDED RELEASE 300 mg ORAL ANDA 15 sections
lithium carbonate HUMAN PRESCRIPTION DRUG LABEL 1 31722-544 CAPSULE 150 mg ORAL ANDA 26 sections
lithium carbonate HUMAN PRESCRIPTION DRUG LABEL 1 31722-545 CAPSULE 300 mg ORAL ANDA 26 sections
lithium carbonate HUMAN PRESCRIPTION DRUG LABEL 1 31722-546 CAPSULE 600 mg ORAL ANDA 26 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 33261-852 CAPSULE 300 mg ORAL ANDA 18 sections
Lithium CarbonateER HUMAN PRESCRIPTION DRUG LABEL 1 42291-496 TABLET 450 mg ORAL ANDA 20 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 43063-901 TABLET, EXTENDED RELEASE 450 mg ORAL ANDA 16 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 43063-901 TABLET, EXTENDED RELEASE 450 mg ORAL ANDA 16 sections
Lithium Carbonate Human Prescription Drug Label 1 46708-148 TABLET, EXTENDED RELEASE 300 mg ORAL ANDA 16 sections
Lithium Carbonate Human Prescription Drug Label 1 46708-303 CAPSULE 150 mg ORAL ANDA 18 sections
Lithium Carbonate Human Prescription Drug Label 1 46708-304 CAPSULE 300 mg ORAL ANDA 18 sections
Lithium Carbonate Human Prescription Drug Label 1 46708-305 CAPSULE 600 mg ORAL ANDA 18 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 50090-1470 TABLET, FILM COATED, EXTENDED RELEASE 300 mg ORAL ANDA 17 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 50090-2754 TABLET, EXTENDED RELEASE 450 mg ORAL ANDA 16 sections
Lithium Carbonate Human Prescription Drug Label 1 50090-3490 TABLET, EXTENDED RELEASE 450 mg ORAL ANDA 13 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 50090-3917 CAPSULE 300 mg ORAL ANDA 25 sections
Lithium Carbonate Human Prescription Drug Label 1 50090-3918 CAPSULE 300 mg ORAL ANDA 24 sections
Lithium Carbonate HUMAN PRESCRIPTION DRUG LABEL 1 50090-6052 TABLET, FILM COATED, EXTENDED RELEASE 300 mg ORAL ANDA 17 sections