All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

carbocisteine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
mucolytics	4160	638-23-3

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: carbocisteine bronchokod carbocit carbocysteine chilvax L-(Carboxymethyl)cysteine lisil lisomucil loviscol muciclar mucocis mucodyne mucofan mucolase mucolex mucopront mucosol mucotab mukinyl PectDrill pectox pulmoclase reomucil rhinathiol rhinatiol thiodril transbronchin carbocisteine sodium	A compound formed when iodoacetic acid reacts with sulfhydryl groups in proteins. It has been used as an anti-infective nasal spray with mucolytic and expectorant action. Molecular weight: 179.19 Formula: C5H9NO4S CLOGP: -2.61 LIPINSKI: 0 HAC: 5 HDO: 3 TPSA: 100.62 ALOGS: -0.92 ROTB: 5

Drug dosage:

Dose	Unit	Route
1.50	g	O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

Property	Description	Value	Unit	Confidence	Similarity
kinase-safety-class	ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AXL,BMX,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT1,FLT3,GRK2,GRK3,GSK3B,IGF1R,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MTOR,NTRK1,NTRK2,PDK1,PDK2,PDK4,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70	67
kinase-selectivity-class	ACVR2B,AXL,BRAF,CDK9,DYRK1B,EIF2AK3,EPHB4,GRK2,MAP2K6,MAP3K14,MAPK7,PIK3CB,PIK3CD,PIK3CG,PRKDC,STK33,TEK,TGFBR1	18
pfas-class	PFAS structural alert (1 = True, 0 = False)	0

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Pulmonary pain	192.83	18.26	54	9980	5060	90613353
Amyloid arthropathy	191.34	18.26	43	9991	1637	90616776
Pneumonia bacterial	95.13	18.26	40	9994	12750	90605663
Upper respiratory tract inflammation	90.71	18.26	26	10008	2646	90615767
Interstitial lung disease	84.46	18.26	69	9965	76336	90542077
Hepatic function abnormal	80.78	18.26	55	9979	46233	90572180
Drug ineffective	76.76	18.26	29	10005	1384269	89234144
Drug eruption	76.26	18.26	48	9986	35359	90583054
Lower respiratory tract infection	61.44	18.26	104	9930	250555	90367858
Platelet count decreased	55.48	18.26	72	9962	136897	90481516
Pain	54.88	18.26	21	10013	996320	89622093
Haemoptysis	54.37	18.26	38	9996	33282	90585131
Adrenal suppression	53.75	18.26	14	10020	995	90617418
Cardiac failure	49.81	18.26	61	9973	109435	90508978
Pneumonia aspiration	49.53	18.26	39	9995	40901	90577512
Hyponatraemia	46.16	18.26	65	9969	133473	90484940
Lip swelling	45.03	18.26	36	9998	38574	90579839
Drug abuse	44.29	18.26	50	9984	82297	90536116
Diarrhoea	42.87	18.26	211	9823	938979	89679434
Intentional product misuse	42.50	18.26	51	9983	89553	90528860
Fatigue	40.55	18.26	41	9993	1153982	89464431
Adjusted calcium decreased	38.10	18.26	8	10026	220	90618193
Upper gastrointestinal haemorrhage	37.01	18.26	26	10008	22950	90595463
Pneumonia	37.01	18.26	154	9880	637905	89980508
Drug interaction	36.78	18.26	89	9945	276364	90342049
Myopathy	35.98	18.26	21	10013	13497	90604916
Product administration error	35.96	18.26	27	10007	26396	90592017
Infective exacerbation of chronic obstructive airways disease	35.40	18.26	11	10023	1475	90616938
Infusion related reaction	35.04	18.26	3	10031	416777	90201636
Asteatosis	34.36	18.26	6	10028	59	90618354
Palpitations	33.80	18.26	57	9977	136671	90481742
Stevens-Johnson syndrome	33.43	18.26	27	10007	29349	90589064
Blood prolactin increased	32.58	18.26	13	10021	3624	90614789
Infective exacerbation of bronchiectasis	32.27	18.26	8	10026	466	90617947
Pyrexia	31.19	18.26	150	9884	660335	89958078
Erythema multiforme	29.92	18.26	18	10016	12228	90606185
Oesophageal irritation	29.60	18.26	7	10027	334	90618079
Sputum retention	29.57	18.26	8	10026	658	90617755
Knee arthroplasty	29.49	18.26	41	9993	83141	90535272
Gastroenteritis	29.37	18.26	25	10009	29204	90589209
Overdose	27.98	18.26	57	9977	157652	90460761
Obesity	27.43	18.26	45	9989	105462	90512951
Systemic lupus erythematosus	26.92	18.26	4	10030	361892	90256521
Glossodynia	25.26	18.26	3	10031	321776	90296637
Anaemia	25.16	18.26	91	9943	352711	90265702
Tendonitis	25.07	18.26	20	10014	21352	90597061
Hypozincaemia	24.80	18.26	4	10030	23	90618390
Enterocolitis	24.55	18.26	15	10019	10475	90607938
Pneumomediastinum	24.43	18.26	9	10025	2022	90616391
Joint swelling	23.89	18.26	13	10021	503287	90115126
Drug dependence	23.36	18.26	22	10012	29305	90589108
Bronchitis	23.34	18.26	52	9982	152875	90465538
Galactorrhoea	23.15	18.26	11	10023	4661	90613752
Asthma	23.13	18.26	69	9965	242091	90376322
Drug-induced liver injury	22.77	18.26	38	9996	90280	90528133
Hypoglycaemia	22.65	18.26	33	10001	69815	90548598
Pharyngitis	22.52	18.26	19	10015	21928	90596485
Urine output decreased	22.03	18.26	15	10019	12588	90605825
Drug hypersensitivity	21.97	18.26	12	10022	463597	90154816
Reversible cerebral vasoconstriction syndrome	21.31	18.26	10	10024	4120	90614293
Sputum increased	21.16	18.26	9	10025	2948	90615465
Maternal exposure during pregnancy	20.74	18.26	7	10027	360056	90258357
Contraindicated product administered	20.70	18.26	5	10029	320134	90298279
Loss of consciousness	19.53	18.26	46	9988	140192	90478221
Enteritis infectious	19.40	18.26	8	10026	2427	90615986
Rheumatoid arthritis	19.29	18.26	8	10026	362606	90255807
Hypoalbuminaemia	18.91	18.26	15	10019	15882	90602531
Depression	18.84	18.26	5	10029	300596	90317817
Atrial fibrillation	18.80	18.26	44	9990	133567	90484846
Pneumothorax	18.46	18.26	16	10018	19151	90599262
Eosinophilic pneumonia	18.39	18.26	8	10026	2765	90615648

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Interstitial lung disease	175.39	16.07	151	10685	78311	42532188
Pneumonia aspiration	129.66	16.07	105	10731	49973	42560526
Hepatic function abnormal	116.64	16.07	100	10736	51467	42559032
Lower respiratory tract infection	93.33	16.07	80	10756	41126	42569373
Pneumonia	90.48	16.07	273	10563	421876	42188623
Radiation inflammation	88.83	16.07	25	10811	1023	42609476
Pulmonary pain	78.73	16.07	25	10811	1553	42608946
Idiopathic pulmonary fibrosis	71.78	16.07	31	10805	4573	42605926
Pneumonia bacterial	60.92	16.07	42	10794	15650	42594849
Drug ineffective	58.70	16.07	45	10791	630152	41980347
Lung neoplasm malignant	51.30	16.07	41	10795	19106	42591393
Fatigue	50.40	16.07	24	10812	435617	42174882
Upper respiratory tract inflammation	44.07	16.07	17	10819	1879	42608620
Genital pain	39.61	16.07	13	10823	897	42609602
Genital ulceration	35.87	16.07	12	10824	879	42609620
Schizophrenia	33.51	16.07	25	10811	10525	42599974
Drug eruption	33.42	16.07	35	10801	23040	42587459
Liver disorder	30.98	16.07	44	10792	39600	42570899
Malignant neoplasm progression	29.79	16.07	77	10759	108323	42502176
Prostate tenderness	29.77	16.07	6	10830	55	42610444
Dyspnoea	29.08	16.07	202	10634	442419	42168080
Pneumothorax	27.66	16.07	32	10804	23511	42586988
Paraneoplastic rash	27.18	16.07	6	10830	88	42610411
Hyponatraemia	26.78	16.07	71	10765	101391	42509108
Drug-induced liver injury	26.32	16.07	40	10796	38233	42572266
Food poisoning	25.90	16.07	13	10823	2693	42607806
Neutrophil count decreased	25.08	16.07	52	10784	63363	42547136
Gastrointestinal pain	25.02	16.07	15	10821	4400	42606099
Hypophagia	24.20	16.07	32	10804	26924	42583575
Antibody test abnormal	23.89	16.07	7	10829	331	42610168
Clumsiness	23.87	16.07	11	10825	1889	42608610
Contusion	23.56	16.07	40	10796	41945	42568554
Malaise	23.20	16.07	111	10725	212045	42398454
Infective exacerbation of chronic obstructive airways disease	23.16	16.07	11	10825	2022	42608477
Sputum retention	22.75	16.07	8	10828	681	42609818
Knee arthroplasty	21.82	16.07	18	10818	8763	42601736
Hallucination	21.39	16.07	46	10790	57461	42553038
Somnambulism	20.39	16.07	12	10824	3403	42607096
Inappropriate antidiuretic hormone secretion	20.30	16.07	23	10813	16518	42593981
Nephrotic syndrome	19.86	16.07	17	10819	8701	42601798
Neuropsychiatric syndrome	19.83	16.07	5	10831	133	42610366
Radiation pneumonitis	19.36	16.07	11	10825	2922	42607577
Irritable bowel syndrome	19.28	16.07	13	10823	4668	42605831
Mouth swelling	19.20	16.07	10	10826	2236	42608263
Toxicity to various agents	19.19	16.07	18	10818	229118	42381381
Gastric mucosal lesion	18.79	16.07	7	10829	703	42609796
Hyperuricaemia	18.72	16.07	17	10819	9407	42601092
Inflammation	18.66	16.07	32	10804	33815	42576684
Sputum increased	18.58	16.07	11	10825	3152	42607347
Duodenal ulcer perforation	18.39	16.07	9	10827	1767	42608732
Cerebral infarction	17.89	16.07	30	10806	31139	42579360
Bronchitis	17.83	16.07	38	10798	47163	42563336
Eye infection	17.69	16.07	12	10824	4349	42606150
Injection site induration	17.59	16.07	11	10825	3476	42607023
Concomitant disease aggravated	17.41	16.07	14	10822	6572	42603927
Fulminant type 1 diabetes mellitus	17.40	16.07	8	10828	1366	42609133
Clonic convulsion	17.37	16.07	7	10829	868	42609631
Lipid metabolism disorder	17.29	16.07	6	10830	491	42610008
Nightmare	16.99	16.07	26	10810	24986	42585513
Orthostatic hypotension	16.98	16.07	29	10807	30541	42579958
Stevens-Johnson syndrome	16.42	16.07	24	10812	22154	42588345
Cardiac failure	16.38	16.07	62	10774	106794	42503705
Platelet count decreased	16.22	16.07	74	10762	138507	42471992
Anxiety	16.19	16.07	5	10831	118555	42491944
Arthralgia	16.17	16.07	17	10819	205221	42405278

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Pulmonary pain	253.23	15.41	79	20981	6214	110562025
Interstitial lung disease	251.76	15.41	210	20850	139124	110429115
Hepatic function abnormal	200.58	15.41	153	20907	89142	110479097
Pneumonia aspiration	184.23	15.41	140	20920	81093	110487146
Amyloid arthropathy	168.10	15.41	43	21017	1637	110566602
Pneumonia bacterial	146.93	15.41	80	20980	26181	110542058
Pneumonia	125.82	15.41	409	20651	876305	109691934
Upper respiratory tract inflammation	123.56	15.41	42	21018	4329	110563910
Drug ineffective	117.10	15.41	73	20987	1520467	109047772
Drug eruption	101.20	15.41	83	20977	53576	110514663
Radiation inflammation	95.98	15.41	25	21035	1023	110567216
Fatigue	88.55	15.41	62	20998	1215896	109352343
Lower respiratory tract infection	86.27	15.41	161	20899	242945	110325294
Pain	73.07	15.41	46	21014	954909	109613330
Platelet count decreased	72.43	15.41	145	20915	230298	110337941
Idiopathic pulmonary fibrosis	71.02	15.41	29	21031	4975	110563264
Hyponatraemia	69.66	15.41	138	20922	217515	110350724
Cardiac failure	62.50	15.41	121	20939	187505	110380734
Haemoptysis	60.06	15.41	71	20989	71283	110496956
Infective exacerbation of chronic obstructive airways disease	54.02	15.41	21	21039	3169	110565070
Pneumothorax	49.24	15.41	46	21014	35239	110533000
Stevens-Johnson syndrome	48.58	15.41	52	21008	46849	110521390
Lip swelling	46.98	15.41	53	21007	50614	110517625
Upper gastrointestinal haemorrhage	45.76	15.41	52	21008	50044	110518195
Knee arthroplasty	45.60	15.41	59	21001	64889	110503350
Neutrophil count decreased	43.98	15.41	81	20979	120860	110447379
Malignant neoplasm progression	43.48	15.41	100	20960	174467	110393772
Dyspnoea	43.47	15.41	359	20701	1106513	109461726
Lung neoplasm malignant	43.20	15.41	42	21018	33800	110534439
Sputum retention	42.13	15.41	14	21046	1345	110566894
Drug hypersensitivity	41.94	15.41	17	21043	454073	110114166
Infusion related reaction	40.92	15.41	11	21049	381151	110187088
Drug-induced liver injury	40.65	15.41	78	20982	119989	110448250
Erythema multiforme	40.53	15.41	33	21027	21064	110547175
Cerebral infarction	39.41	15.41	49	21011	51789	110516450
Sputum increased	39.20	15.41	20	21040	5731	110562508
Genital pain	37.80	15.41	13	21047	1387	110566852
Pyrexia	37.74	15.41	296	20764	897969	109670270
Diarrhoea	37.70	15.41	356	20704	1139149	109429090
Prostate tenderness	36.76	15.41	7	21053	64	110568175
Tendonitis	36.39	15.41	34	21026	26049	110542190
Hypozincaemia	35.59	15.41	7	21053	77	110568162
Adrenal suppression	35.36	15.41	13	21047	1683	110566556
Completed suicide	35.00	15.41	3	21057	242378	110325861
Chronic obstructive pulmonary disease	34.63	15.41	69	20991	109089	110459150
Asthenia	34.11	15.41	49	21011	688950	109879289
Nephrotic syndrome	33.91	15.41	25	21035	13806	110554433
Enterocolitis	32.99	15.41	28	21032	18921	110549318
Intentional product misuse	32.94	15.41	76	20984	132828	110435411
Toxicity to various agents	32.90	15.41	26	21034	480529	110087710
Adjusted calcium decreased	32.82	15.41	8	21052	249	110567990
Bronchitis	32.73	15.41	84	20976	156948	110411291
Febrile convulsion	32.69	15.41	11	21049	1099	110567140
Weight increased	32.30	15.41	20	21040	419624	110148615
Systemic lupus erythematosus	32.13	15.41	5	21055	254333	110313906
Glossodynia	31.38	15.41	3	21057	222001	110346238
Wound	31.03	15.41	4	21056	234433	110333806
Pericarditis	30.87	15.41	3	21057	219111	110349128
Hyperuricaemia	30.62	15.41	24	21036	14507	110553732
Discomfort	30.09	15.41	3	21057	214704	110353535
Pneumomediastinum	30.00	15.41	16	21044	5020	110563219
Genital ulceration	29.93	15.41	12	21048	1963	110566276
Paraneoplastic rash	28.84	15.41	6	21054	89	110568150
Orthostatic hypotension	28.79	15.41	48	21012	66201	110502038
Therapeutic product effect decreased	28.28	15.41	6	21054	244310	110323929
Maternal exposure during pregnancy	28.02	15.41	7	21053	254876	110313363
Treatment failure	27.92	15.41	9	21051	277225	110291014
Respiratory failure	27.60	15.41	97	20963	215235	110353004
Lymphangiosis carcinomatosa	27.29	15.41	12	21048	2470	110565769
Hypophagia	26.81	15.41	41	21019	52585	110515654
Arthralgia	26.75	15.41	69	20991	779563	109788676
Altered state of consciousness	26.72	15.41	43	21017	57583	110510656
Food poisoning	26.49	15.41	16	21044	6356	110561883
Rheumatoid arthritis	26.40	15.41	12	21048	299601	110268638
Constipation	26.24	15.41	136	20924	357650	110210589
Radiation pneumonitis	25.86	15.41	14	21046	4522	110563717
Schizophrenia	25.84	15.41	26	21034	21800	110546439
Disseminated intravascular coagulation	25.14	15.41	35	21025	41251	110526988
Abnormal behaviour	25.14	15.41	34	21026	39005	110529234
Hallucination	25.12	15.41	58	21002	101374	110466865
Malaise	24.73	15.41	215	20845	671604	109896635
Fulminant type 1 diabetes mellitus	24.61	15.41	11	21049	2352	110565887
Pharyngitis	24.54	15.41	27	21033	25071	110543168
Weight decreased	24.43	15.41	32	21028	468025	110100214
Renal impairment	24.24	15.41	85	20975	188360	110379879
Infective exacerbation of bronchiectasis	23.13	15.41	8	21052	868	110567371
Rash	22.97	15.41	248	20812	820716	109747523
Asthma	22.58	15.41	101	20959	250190	110318049
Blood cholesterol increased	22.52	15.41	4	21056	184781	110383458
Asteatosis	22.41	15.41	6	21054	273	110567966
Enteritis infectious	22.19	15.41	12	21048	3870	110564369
Clonic convulsion	21.89	15.41	9	21051	1571	110566668
Oesophageal irritation	21.89	15.41	6	21054	299	110567940
Laryngopharyngitis	21.88	15.41	5	21055	117	110568122
Folliculitis	21.85	15.41	3	21057	167650	110400589
Mobility decreased	21.72	15.41	9	21051	237413	110330826
Sinusitis	21.65	15.41	15	21045	296673	110271566
Palpitations	21.51	15.41	73	20987	159139	110409100
COVID-19	21.44	15.41	98	20962	244962	110323277
Joint swelling	21.39	15.41	32	21028	442813	110125426
Fixed eruption	21.22	15.41	12	21048	4220	110564019
Liver disorder	20.80	15.41	67	20993	142176	110426063
Memory impairment	20.53	15.41	6	21054	196938	110371301
Gastric mucosal lesion	20.43	15.41	8	21052	1231	110567008
Drug reaction with eosinophilia and systemic symptoms	20.39	15.41	47	21013	82048	110486191
Blood prolactin increased	20.19	15.41	12	21048	4630	110563609
Paraesthesia	20.15	15.41	14	21046	276507	110291732
Osteoarthritis	20.10	15.41	5	21055	182618	110385621
Melaena	20.07	15.41	42	21018	68715	110499524
Hepatic enzyme increased	19.96	15.41	19	21041	320873	110247366
Immunosuppressant drug level increased	19.75	15.41	17	21043	11707	110556532
Clumsiness	19.72	15.41	11	21049	3769	110564470
Exposure during pregnancy	19.60	15.41	4	21056	167420	110400819
Gastroenteritis	19.44	15.41	30	21030	38770	110529469
General physical health deterioration	19.33	15.41	32	21028	425263	110142976
Type 2 diabetes mellitus	19.22	15.41	5	21055	177227	110391012
Adrenocorticotropic hormone deficiency	19.10	15.41	9	21051	2173	110566066
Alopecia	18.96	15.41	25	21035	364728	110203511
Neuropsychiatric syndrome	18.89	15.41	5	21055	218	110568021
Asphyxia	18.81	15.41	18	21042	14197	110554042
Diabetes mellitus	18.51	15.41	51	21009	99330	110468909
Depression	18.36	15.41	20	21040	317315	110250924
Product use in unapproved indication	18.24	15.41	36	21024	447341	110120898
Antibody test abnormal	18.04	15.41	7	21053	1051	110567188
Drug abuse	17.84	15.41	74	20986	177337	110390902
Physical deconditioning	17.65	15.41	10	21050	3527	110564712
Lipid metabolism disorder	17.37	15.41	6	21054	648	110567591
Mouth swelling	17.37	15.41	13	21047	7341	110560898
Overdose	17.22	15.41	89	20971	233705	110334534
Lung adenocarcinoma stage II	17.17	15.41	3	21057	16	110568223
Duodenal perforation	17.06	15.41	9	21051	2761	110565478
Inappropriate antidiuretic hormone secretion	16.71	15.41	26	21034	33825	110534414
Concomitant disease aggravated	16.69	15.41	18	21042	16346	110551893
Iron deficiency anaemia	16.66	15.41	25	21035	31534	110536705
Zinc deficiency	16.53	15.41	5	21055	354	110567885
Non-small cell lung cancer	16.49	15.41	13	21047	7922	110560317
Oculomucocutaneous syndrome	16.49	15.41	5	21055	357	110567882
Hyperkalaemia	16.39	15.41	60	21000	135736	110432503
Decreased appetite	16.30	15.41	150	20910	475696	110092543
Contraindicated product administered	16.27	15.41	14	21046	248253	110319986
Pleural effusion	16.23	15.41	72	20988	177637	110390602
Injection site induration	16.19	15.41	15	21045	11368	110556871
Galactorrhoea	16.16	15.41	10	21050	4145	110564094
Urine flow decreased	16.11	15.41	7	21053	1399	110566840
Productive cough	15.95	15.41	53	21007	114252	110453987
Sleep disorder	15.93	15.41	9	21051	198635	110369604
Injection site pain	15.86	15.41	7	21053	177915	110390324
Intentional overdose	15.86	15.41	3	21057	132498	110435741
Musculoskeletal stiffness	15.78	15.41	18	21042	279804	110288435
Gastrointestinal pain	15.66	15.41	15	21045	11845	110556394
Anaemia	15.60	15.41	166	20894	546920	110021319
Cardiac failure acute	15.55	15.41	21	21039	24057	110544182
Myositis	15.50	15.41	24	21036	31092	110537147
Urine output decreased	15.45	15.41	19	21041	19857	110548382

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	R05CB03	RESPIRATORY SYSTEM COUGH AND COLD PREPARATIONS EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS Mucolytics
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000891	Anti-Infective Agents, Local
MeSH PA	D005100	Expectorants
MeSH PA	D019141	Respiratory System Agents
CHEBI has role	CHEBI:77034	mucolytics

Related Drugs by ATC class:

R05CB Mucolytics 13 drugs

acetylcysteineambroxolbromhexinedomiodoldornase alfaeprazinoneerdosteineletosteinemannitolmesnaneltenexinesobrerol show all 13 →

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Gastrointestinal ulcer	contraindication	40845000
Gastrointestinal hemorrhage	contraindication	74474003

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	2.15	acidic
pKa2	2.79	acidic
pKa3	9.51	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
N0000170286	NUI
D06393	KEGG_DRUG
C0006992	UMLSCUI
CHEBI:16163	CHEBI
CAY	PDB_CHEM_ID
CCS	PDB_CHEM_ID
CHEMBL396416	ChEMBL_ID
DB04339	DRUGBANK_ID
193653	PUBCHEM_CID
2023	RXNORM
26469	MMSL
d05062	MMSL
003677	NDDF
395842001	SNOMEDCT_US
772923009	SNOMEDCT_US
D002233	MESH_DESCRIPTOR_UI
2884	INN_ID
740J2QX53R	UNII

Pharmaceutical products:

None